Pulmonary & Critical Care Medicine

NIH Grants 1975 2020

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Research project

Expression Analysis to Study Disease Pathogenesis

Geraci, M.

National Institutes of Health

9/30/027/31/08

Project: Research project

National Heart, Lung, and Blood Institute (U.S.)
Research Personnel
Computational Biology
Internet
Oligonucleotide Array Sequence Analysis

Role of anti-Col (V) immunity in primary graft dysfunction

Wilkes, D. & Christie, J.

National Institutes of Health

5/14/104/30/16

Project: Research project

Primary Graft Dysfunction
Immunity
Lung Transplantation
Autoimmunity
Transplants
Genomics
Lung Diseases
Medical Genetics
Genetic Research
Research

IMMUNE RESPONSES IN LUNG ALLOGRAFT REJECTION

Wilkes, D.

National Institutes of Health

3/15/994/30/08

Project: Research project

Allografts
Lung
Major Histocompatibility Complex
Indoleamine-Pyrrole 2,3,-Dioxygenase
Dendritic Cells
Immune Tolerance
Allografts
Lung
Bronchiolitis Obliterans
Major Histocompatibility Complex

Colorado CTSA Planning Grant

Geraci, M.

National Institutes of Health

9/23/0611/7/07

Project: Research project

Organized Financing
Translational Medical Research
Education
Research
Biomedical Research

Lung Genomics Research Consortium

Geraci, M., Quackenbush, J., Spira, A., Kaminski, N., Schwartz, D. A. & Sciurba, F.

National Institutes of Health

9/30/098/31/12

Project: Research project

Genomics
Lung
Research
Lung Diseases
Molecular Biology
Bombesin
Carrier Proteins
Lung
Peptides
Lung Diseases

PI3-K and Akt in Acute Lung Injury

Geraci, M., Nick, J., Leung, D., Abraham, E. & Dinarello, C. A.

National Institutes of Health

7/1/026/30/08

Project: Research project

Molecular Biology
Neutrophils
Bronchoalveolar Lavage
Gene Expression
Endotoxins

CHARACTERIZATION OF P2-PURINERGIC RECEPTORS

Wilkes, D., Goodman, G. A. Y., Martin, W. & Sturek, M.

National Institutes of Health

9/25/884/30/11

Project: Research project

Delirium
Intensive Care Units
Biomarkers
Biostatistics
Translational Medical Research
Antibodies, Monoclonal, Humanized
Emphysema
Lung
Chronic Obstructive Pulmonary Disease
Smoke
alpha 1-Antitrypsin
Chronic Obstructive Pulmonary Disease
Blood Vessels
Emphysema
Smoke
Emphysema
Stem Cells
Bone Marrow
Smoke
Tobacco Products
Endothelial Cells
Apoptosis
Tumor Necrosis Factor-alpha
Cytoskeleton
Lung Injury

Pulmonary Hypertension Breakthrough Initiative

Geraci, M., Rabinovitch, M., Erzurum, S. C., Grizzle, W. E. & McLaughlin, V.

National Institutes of Health

9/15/146/30/18

Project: Research project

Pulmonary Hypertension
National Heart, Lung, and Blood Institute (U.S.)
Cataloging
Pathology
Lung

CANCER CENTER CORE GRANT

Geraci, M., Braun, T., Mmaller, J., Hirs, W. C., Scoggin, C., Hendrick, E., Archer, P., Patterson, D., Miller, G., Schmeler, R., Kolhouse, F., Johnston, M., Krebs, L., Talmage, D., Kraft, A., Johnson, G., Jones, D. N., Pfenninger, K., Irons, R., Garcea, R., Cole, W., Kavanagh, B., Williams, T., Bondy, J., Ullrich, R., Tran, Z., Gutierrez-Hartmann, A., Varella-Garcia, M., Kane, M., Duncan, M., Bellgrau, D., Elias, A., Marcus, A. L., Reardon, C., Anderson, S., Eckhardt, S. G., Gustafson, D., Holt, J., Sclafani, R., Miller, Y., Churchill, M., Byers, T., Theodorescu, D. A. N., Marcus, A., Hendrick, R., Duke, R., McManaman, J. L., McHenry, C., Murphy, J. R., Gemmill, R., Bearman, S., Franklin, W., Bunn, P., Edwards, D., Drabkin, H. A. & Stevens, J.

National Institutes of Health

3/1/881/31/17

Project: Research project

Gene Expression
Neoplasms
Oligonucleotide Array Sequence Analysis
Genomics
Technology

Pathobiology of Severe Pulmonary Hypertension

Geraci, M., Franklin, W., Abman, S. H., Tuder, R. & Voelkel, N.

National Institutes of Health

9/17/017/31/07

Project: Research project

Epoprostenol Receptors
Epoprostenol
Smooth Muscle Myocytes
Lung
Vascular Smooth Muscle
Acute Lung Injury
Molecular Imaging
Carbon Monoxide
Lung
Lung Diseases

Affymetrix GeneChip Instrument System

Geraci, M.

National Institutes of Health

3/1/042/28/05

Project: Research project

Fluidics
Gene expression
Microarrays
Chemical vapor deposition
Washing

Type V Collagen Prevents Lung Allograft Rejection

Wilkes, D.

National Institutes of Health

5/1/017/31/12

Project: Research project

Collagen Type V
Allografts
Lung
Autoimmunity
Bronchiolitis
Systems Biology
Lung Diseases
Lung
Research Personnel
Integrative Medicine

TH17 Autoimmunity to Type V Collagen in Heart and Lung Transplant

Wilkes, D., Griep, A., Burlingham, W., Torrealba, J. R. & Greenspan, D.

National Institutes of Health

9/15/108/31/15

Project: Research project

Collagen Type V
Allografts
Lung
Autoimmunity
Interleukin-17

Common targeting of the prostacyclin-PPARy axis in COPD and lung cancer

Geraci, M., Tuder, R. & Tuder, R. M.

National Institutes of Health

8/15/115/31/16

Project: Research project

Epoprostenol
Smoke
Chronic Obstructive Pulmonary Disease
Tobacco
Lung Neoplasms
Epithelial-Mesenchymal Transition
Interleukin-17
Idiopathic Pulmonary Fibrosis
Bronchiolitis
Lung

Genomic Analysis of Immunity and Lung Inflammation in HIV Infection

Twigg, H., Knox, K. & Weinstock, G.

National Institutes of Health

9/26/137/31/18

Project: Research project

HIV Infections
Immunity
Pneumonia
Highly Active Antiretroviral Therapy
HIV
HIV Infections
Cytotoxic T-Lymphocytes
Immunity
Lung
Alveolar Epithelial Cells

GENERAL CLINICAL RESEARCH CENTER

Wilkes, D., Crabb, D., Rex, D., Einhorn, L., Zipes, D., Benson, M., Moe, S., Abonour, R., Farlow, M., Miller, K., Loehrer, P., Cripe, L., Peacock, M., DiMeglio, L., Econs, M., Spinola, S., de Cordon, K., Denne, S., Kwo, P., Agarwal, R., Considine, R., Poindexter, B., Stevens, J., Kraus, M., Chalasani, N., Robertson, M., Logan, T., Croop, J., Groh, W., Robertson, M., Hannon, T., Wojcieszek, J., Considine, R., Mather, K., Chalasani, N., Flockhart, D. A., Foroud, T., Desta, Z., Benson, M., Kareken, D., Poindexter, B., Friedman, A., Gupta, S., Schneider, B., Carpenter, J., Steiner, S., Storniolo, A. M., Cripe, L., Murphy, M., Molleston, J., Hui, S., Von Ah, D., Logan, T., Sawada, S., Fineberg, S. E., Edmondson, J. W., Lumeng, L., O'Connor, K., Clark, C. M., Maxwell, D., Scott, P., Prystowsky, E., Hoffman, R., Brater, C. D., Brandt, I., Bradley, J., Vinicor, F., Williams, S., Weir, C., Heger, J., Thomasson, H., Manolagas, S., Duckworth, W., MacLaren, N., Mohler, E., Baker, J., Vargo, D., Lehman, G., Einhorm, L., Luft, F., Scheller, C., Rudy, D., Merritt, D. H., Kleit, S., Williams, D., Wheeler, M., Twigg, H., Weinberger, M., Wheat, L. J., Holden, R., Rawl, S., Smith, F. O., Shankar, R., Kirkman, S. U. E., Richardson, J., Pratt, J. H., Rodriguez, H., Hall, S., McDougle, C., Brater, D. C., Dropco, E., Krause, M., Baker, S., Wilensky, R., Hamburger, R., Jakacki, R., Oconnor, S., Rink, R., Biller, J., Prince, M., Klaunig, J., Reed, T. E., Harris, A., Myers, S., Jackson, R., Jindal, R., Haehner, B., Johnston, C. C., Black, J., McCaskill-Steve, W., Clark, C., Roos, K., Batiuk, T., Brady, M., Oconner, S., Keck, J., Brashear, A., Timmerman, R., Goldmna, M., Mohler, E. R., Guare, J., Frank, M., Siemers, E., Dropcho, E. J., Davidson, D., Pompili, V., Patrick Loehrer, M. D., Gumbiner, B., Michael Frank, M. D., Wheat, L. J., O'Connor, S., Dusick, A., Ernst, J., Sowinski, K., Batiuk, T., Rushing, D., Stout, J., Bangs, M., Sokol, G., Lemons, J., Gorski, J. C., Johnson, R., Sweeney, C., Dennis Chua, A., Dube, M., Galinsky, R. E., Steinberg, H., Pescovitz, M. D., Twigg, H., Fife, K. H., O'Connor, S. J., Tisdale, J. E., Vik, T., Govani, M., Gardner, T. W., Blekher, T., Kays, M., Johnston, C., Howenstine, M., Dusick, A., Yaqub, M., Kreher, N., Morris, E., Posey, D., Nebesio, T., Ragg, S., Kowolik, M., Ellett, M., Shankar, S., Walvoord, E., Shore, C., Deeg, M., Matei, D., Tisdale, J. E., Bruno, A., Knox, K., Stout, J., Blekher, T., Saifullah, A., Jin, Y. A. N., Griest, A., Nurnberger, J., Hathaway, D., Voelker, J., Abel, L., Faust, H., Brater, C., Garcia, J. O. E., Garvey, T., Johnston, C. C., Fergusson, J., O'Connor, S., Greist, A., Shapiro, A. M. Y., Eigen, H., Roth, B. J., Pescovitz, O., Lemons, J., Pescovitz, M., Rickard, K., Christian, J., Sokol, G., Bradley, J. D., Steinberg, H., Freidenberg, G., Wheat, J., Fife, K., Gordon, M., Pratt, H., Mannix, E., Sledge, G., Sandler, A., Baron, A., Leitch, C. & Goldman, M.

National Institutes of Health

12/1/7611/30/09

Project: Research project

salmon calcitonin
Haemophilus ducreyi
Amyloidosis
Osteoporotic Fractures
Osteoporosis

ACCESSORY CELLS AND LUNG ALLOGRAFT REJECTION

Wilkes, D.

National Institutes of Health

8/1/967/31/02

Project: Research project

Allografts
Lung
Critical Care
Medicine
Dendritic Cells
Epoprostenol Receptors
Pulmonary Hypertension
Peroxisome Proliferator-Activated Receptors
Epoprostenol
Modifier Genes

MMPs in Alloimmune and Autoimmune Lung Disease

Wilkes, D.

National Institutes of Health

7/12/055/31/09

Project: Research project

Matrix Metalloproteinases
Lung Diseases
Autoimmune Diseases
Lung
Allografts
Microbiota
Virus Diseases
Immunity
Pneumonia
HIV

MULTIPURPOSE ARTHRITIS &MUSCULOSKELETAL DISEASES CENTER

Wilkes, D., Vasko, M., Vilensky, J., Benson, M., Hugenberg, S., Katz, B., Buckwalter, K., Dines, K., Fitzgerald, J., Brandt, K., Weinberger, M., Mikesky, A., Yokota, H., Bradley, J., Slemenda, C., Jacobs, M. & Mazzuca, S.

National Institutes of Health

9/15/773/31/04

Project: Research project

Joints
Feasibility Studies
Knee
Collagen Type V
Osteoarthritis
Pulmonary Emphysema
Emphysema
Apoptosis
Inflammation
Lung

Signaling Sphingolipids in COPD

Petrache, I., Berdyshev, E. & Petrache, I.

National Institutes of Health

9/19/087/31/11

Project: Research project

Sphingolipids
Chronic Obstructive Pulmonary Disease
Emphysema
Lung
Ceramides

Endothelial mechanisms of impaired lung gas exchange by HIV

Petrache, I., Crothers, K. A. & Schnapp, L.

National Institutes of Health

9/11/1410/31/15

Project: Research project

Gases
HIV
Lung
Emphysema
Chronic Obstructive Pulmonary Disease
Ceramides
Emphysema
Lung
Alveolar Epithelial Cells
Smoke
Ceramides
Smoke
Tobacco Products
Wounds and Injuries
Lung