Publications

Filter
Article
2013

Aromatase inhibitor-induced modulation of breast density: Clinical and genetic effects

Henry, N. L., Chan, H. P., Dantzer, J., Goswami, C. P., Li, L., Skaar, T. C., Rae, J. M., Desta, Z., Khouri, N., Pinsky, R., Oesterreich, S., Zhou, C., Hadjiiski, L., Philips, S., Robarge, J., Nguyen, A. T., Storniolo, A. M., Flockhart, D. A., Hayes, D. F., Helvie, M. A. & 1 others, Stearns, V., Oct 29 2013, In : British Journal of Cancer. 109, 9, p. 2331-2339 9 p.

Research output: Contribution to journalArticle

16 Scopus citations

C-reactive protein and fibrin clot strength measured by thrombelastography after coronary stenting

Kreutz, R. P., Owens, J., Breall, J. A., Lu, D., Lohe, E. V. D., Bolad, I., Sinha, A. & Flockhart, D. A., Apr 2013, In : Blood Coagulation and Fibrinolysis. 24, 3, p. 321-326 6 p.

Research output: Contribution to journalArticle

16 Scopus citations

CYP2D6 genotypes, endoxifen levels, and disease recurrence in 224 Filipino and Vietnamese women receiving adjuvant tamoxifen for operable breast cancer

Love, R. R., Desta, Z., Flockhart, D., Skaar, T., Ogburn, E. T., Ramamoorthy, A., Uy, G. B., Laudico, A. V., van Dinh, N., Quang, L. H., van To, T., Young, G. S., Hade, E. & Jarjoura, D., Jan 1 2013, In : SpringerPlus. 2, 1, p. 1-5 5 p., 52.

Research output: Contribution to journalArticle

22 Scopus citations

Cytochrome P450 3A4*22, PPAR-α, and ARNT polymorphisms and clopidogrel response

Kreutz, R. P., Owens, J., Jin, Y., Nystrom, P., Desta, Z., Kreutz, Y., Breall, J. A., Li, L., Chiang, C. W., Kovacs, R. J. & Flockhart, D. A., Dec 9 2013, In : Clinical Pharmacology: Advances and Applications. 5, p. 185-192 8 p.

Research output: Contribution to journalArticle

13 Scopus citations

Effects of clopidogrel and itraconazole on the disposition of efavirenz and its hydroxyl metabolites: Exploration of a novel CYP2B6 phenotyping index

Jiang, F., Desta, Z., Shon, J. H., Yeo, C. W., Kim, H. S., Liu, K. H., Bae, S. K., Lee, S. S., Flockhart, D. A. & Shin, J. G., Jan 2013, In : British Journal of Clinical Pharmacology. 75, 1, p. 244-253 10 p.

Research output: Contribution to journalArticle

20 Scopus citations

Genetic associations with toxicity-related discontinuation of aromatase inhibitor therapy for breast cancer

Henry, N. L., Skaar, T. C., Dantzer, J., Li, L., Kidwell, K., Gersch, C., Nguyen, A. T., Rae, J. M., Desta, Z., Oesterreich, S., Philips, S., Carpenter, J. S., Storniolo, A. M., Stearns, V., Hayes, D. F. & Flockhart, D. A., Apr 2013, In : Breast Cancer Research and Treatment. 138, 3, p. 807-816 10 p.

Research output: Contribution to journalArticle

34 Scopus citations

Genome-wide discovery of genetic variants affecting tamoxifen sensitivity and their clinical and functional validation

Weng, L., Ziliak, D., Im, H. K., Gamazon, E. R., Philips, S., Nguyen, A. T., Desta, Z., Skaar, T. C., Flockhart, D. A. & Huang, R. S., Jul 1 2013, In : Annals of Oncology. 24, 7, p. 1867-1873 7 p., mdt125.

Research output: Contribution to journalArticle

6 Scopus citations

Gingival evaluation of the pediatric cardiac patient

Nosrati, E., Eckert, G. J., Kowolik, M. J., Ho, J. G., Schamberger, M. S. & Kowolik, J. E., Sep 2013, In : Pediatric dentistry. 35, 5, p. 456-462 7 p.

Research output: Contribution to journalArticle

6 Scopus citations

Inhibition of cytochrome P450 enzymes by the E-and Z-isomers of norendoxifen

Liu, J., Flockhart, P. J., Lu, D., Lv, W., Lu, W. J., Han, X., Cushman, M. & Flockhart, D. A., Sep 2013, In : Drug Metabolism and Disposition. 41, 9, p. 1715-1720 6 p.

Research output: Contribution to journalArticle

11 Scopus citations

Inhibition of platelet aggregation by prostaglandin E1 (PGE1) in diabetic patients during therapy with clopidogrel and aspirin

Kreutz, R. P., Nystrom, P., Kreutz, Y., Miao, J., Kovacs, R., Desta, Z., Flockhart, D. A. & Jin, Y., Feb 11 2013, In : Platelets. 24, 2, p. 145-150 6 p.

Research output: Contribution to journalArticle

16 Scopus citations

Is (+)-[13C]-pantoprazole better than (±)-[ 13C]-pantoprazole for the breath test to evaluate CYP2C19 enzyme activity?

Thacker, D. L., Modak, A., Flockhart, D. A. & Desta, Z., Mar 2013, In : Journal of Breath Research. 7, 1, 016001.

Research output: Contribution to journalArticle

7 Scopus citations

Knowledge and attitude of dental trauma among mothers in Iraq

Yassen, G. H., Chin, J. R., Younus, M. S. & Eckert, G. J., Aug 1 2013, In : European Archives of Paediatric Dentistry. 14, 4, p. 259-265 7 p.

Research output: Contribution to journalArticle

4 Scopus citations

Pharmacogenomics of selective serotonin reuptake inhibitor treatment for major depressive disorder: Genome-wide associations and functional genomics

Ji, Y., Biernacka, J. M., Hebbring, S., Chai, Y., Jenkins, G. D., Batzler, A., Snyder, K. A., Drews, M. S., Desta, Z., Flockhart, D., Mushiroda, T., Kubo, M., Nakamura, Y., Kamatani, N., Schaid, D., Weinshilboum, R. M. & Mrazek, D. A., Oct 1 2013, In : Pharmacogenomics Journal. 13, 5, p. 456-463 8 p.

Research output: Contribution to journalArticle

44 Scopus citations

PharmGKB summary: Tamoxifen pathway, pharmacokinetics

Klein, D. J., Thorn, C. F., Desta, Z., Flockhart, D. A., Altman, R. B. & Klein, T. E., Nov 2013, In : Pharmacogenetics and Genomics. 23, 11, p. 643-647 5 p.

Research output: Contribution to journalArticle

41 Scopus citations

Regulation of microRNA expression by rifampin in human hepatocytes

Ramamoorthy, A., Liu, Y., Philips, S., Desta, Z., Lin, H., Goswami, C., Gaedigk, A., Li, L., Flockhart, D. A. & Skaar, T. C., Oct 2013, In : Drug Metabolism and Disposition. 41, 10, p. 1763-1768 6 p.

Research output: Contribution to journalArticle

27 Scopus citations

Results of an International Randomized Phase III Trial of the Mammalian Target of Rapamycin Inhibitor Ridaforolimus Versus Placebo to Control Metastatic Sarcomas in Patients after Benefit from Prior Chemotherapy

Demetri, G. D., Chawla, S. P., Ray-Coquard, I., Le Cesne, A., Staddon, A. P., Milhem, M. M., Penel, N., Riedel, R. F., Bui-Nguyen, B., Cranmer, L. D., Reichardt, P., Bompas, E., Alcindor, T., Rushing, D., Song, Y., Lee, R. M., Ebbinghaus, S., Eid, J. E., Loewy, J. W., Haluska, F. G. & 2 others, Dodion, P. F. & Blay, J. Y., Jul 1 2013, In : Journal of Clinical Oncology. 31, 19, p. 2485-2492 8 p.

Research output: Contribution to journalArticle

148 Scopus citations

Riga-Fede Disease: A Case Report

Dunlop, R., Barton, D. & Jones, J., Mar 1 2013, In : Journal of Pediatric Health Care. 27, 2, p. 155-157 3 p.

Research output: Contribution to journalArticle

2 Scopus citations

Selective estrogen receptor modulators and pharmacogenomic variation in ZNF423 regulation of BRCA1 expression: Individualized breast cancer prevention

Ingle, J. N., Liu, M., Lawrence Wickerham, D., Schaid, D. J., Wang, L., Mushiroda, T., Kubo, M., Costantino, J. P., Vogel, V. G., Paik, S., Goetz, M. P., Ames, M. M., Jenkins, G. D., Batzler, A., Carlson, E. E., Flockhart, D. A., Wolmark, N., Nakamura, Y. & Weinshilboum, R. M., Jul 2013, In : Cancer Discovery. 3, 7, p. 812-825 14 p.

Research output: Contribution to journalArticle

38 Scopus citations

Synthesis of mixed (E, Z)-, (E)-, and (Z)-norendoxifen with dual aromatase inhibitory and estrogen receptor modulatory activities

Lv, W., Liu, J., Lu, D., Flockhart, D. A. & Cushman, M., Jun 13 2013, In : Journal of Medicinal Chemistry. 56, 11, p. 4611-4618 8 p.

Research output: Contribution to journalArticle

32 Scopus citations

Traumatic injuries of permanent teeth among 6- to 12-year-old iraqi children: A 4-year retrospective study

Yassen, G. H., Chin, J. R., Al-Rawi, B. A. O., Mohammedsharif, A. G., Alsoufy, S. S., Hassan, L. A. R., Salim, L. H. & Eckert, G., Jan 1 2013, In : Journal of Dentistry for Children. 80, 1, p. 3-8 6 p.

Research output: Contribution to journalArticle

10 Scopus citations
2014

Antenatal and intrapartum risk factors for use of emergency and restorative medicaid dental services for children

Yepes, J. F., Bush, H. M., Li, H. F., Talbert, J. & Nash, D. A., Sep 1 2014, In : Pediatric dentistry. 36, 5, p. 405-410 6 p.

Research output: Contribution to journalArticle

1 Scopus citations

Citalopram and escitalopram plasma drug and metabolite concentrations: Genome-wide associations

Ji, Y., Schaid, D. J., Desta, Z., Kubo, M., Batzler, A. J., Snyder, K., Mushiroda, T., Kamatani, N., Ogburn, E., Hall-Flavin, D., Flockhart, D., Nakamura, Y., Mrazek, D. A. & Weinshilboum, R. M., Aug 2014, In : British Journal of Clinical Pharmacology. 78, 2, p. 373-383 11 p.

Research output: Contribution to journalArticle

45 Scopus citations

Efavirenz-mediated induction of omeprazole metabolism is CYP2C19 genotype dependent

Michaud, V., Kreutz, Y., Skaar, T., Ogburn, E., Thong, N., Flockhart, D. A. & Desta, Z., Apr 2014, In : Pharmacogenomics Journal. 14, 2, p. 151-159 9 p.

Research output: Contribution to journalArticle

8 Scopus citations

Factor XIII Val34Leu polymorphism and recurrent myocardial infarction in patients with coronary artery disease

Kreutz, R. P., Bitar, A., Owens, J., Desta, Z., Breall, J. A., Von Der Lohe, E., Sinha, A., Vatta, M., Nystrom, P., Jin, Y. & Flockhart, D. A., Oct 2014, In : Journal of Thrombosis and Thrombolysis. 38, 3, p. 380-387 8 p.

Research output: Contribution to journalArticle

10 Scopus citations

Genetic variant predicts bevacizumab-induced hypertension in ECOG-5103 and ECOG-2100

Schneider, B. P., Li, L., Shen, F., Miller, K. D., Radovich, M., O'Neill, A., Gray, R. J., Lane, D., Flockhart, D. A., Jiang, G., Wang, Z., Lai, D., Koller, D., Pratt, J. H., Dang, C. T., Northfelt, D., Perez, E. A., Shenkier, T., Cobleigh, M., Smith, M. L. & 7 others, Railey, E., Partridge, A., Gralow, J., Sparano, J., Davidson, N. E., Foroud, T. & Sledge, G. W., Sep 9 2014, In : British Journal of Cancer. 111, 6, p. 1241-1248 8 p.

Research output: Contribution to journalArticle

26 Scopus citations

One Size Fits One: Pharmacogenetics in Gastroenterology

Porayette, P., Flockhart, D. & Gupta, S. K., Apr 2014, In : Clinical Gastroenterology and Hepatology. 12, 4, p. 565-570 6 p.

Research output: Contribution to journalArticle

2 Scopus citations

Patient-reported symptoms and discontinuation of adjuvant aromatase inhibitor therapy

Kidwell, K. M., Harte, S. E., Hayes, D. F., Storniolo, A. M., Carpenter, J., Flockhart, D. A., Stearns, V., Clauw, D. J., Williams, D. A. & Henry, N. L., Aug 15 2014, In : Cancer. 120, 16, p. 2403-2411 9 p.

Research output: Contribution to journalArticle

38 Scopus citations

Pharmacoepidemiologic and in vitro evaluation of potential drug-drug interactions of sulfonylureas with fibrates and statins

Schelleman, H., Han, X., Brensinger, C. M., Quinney, S. K., Bilker, W. B., Flockhart, D. A., Li, L. & Hennessy, S., Sep 2014, In : British Journal of Clinical Pharmacology. 78, 3, p. 639-648 10 p.

Research output: Contribution to journalArticle

13 Scopus citations

PharmGKB summary: Ifosfamide pathways, pharmacokinetics and pharmacodynamics

Lowenberg, D., Thorn, C. F., Desta, Z., Flockhart, D. A., Altman, R. B. & Klein, T. E., Feb 2014, In : Pharmacogenetics and Genomics. 24, 2, p. 133-138 6 p.

Research output: Contribution to journalArticle

3 Scopus citations

Prerequisites to implementing a pharmacogenomics program in a large health-care system

Levy, K. D., Decker, B. S., Carpenter, J. S., Flockhart, D. A., Dexter, P. R., Desta, Z. & Skaar, T. C., Sep 2014, In : Clinical Pharmacology and Therapeutics. 96, 3, p. 307-309 3 p.

Research output: Contribution to journalArticle

23 Scopus citations

Simulation with cells in vitro of tamoxifen treatment in premenopausal breast cancer patients with different CYP2D6 genotypes

Maximov, P. Y., McDaniel, R. E., Fernandes, D. J., Korostyshevskiy, V. R., Bhatta, P., Mürdter, T. E., Flockhart, D. A. & Jordan, V. C., Dec 2014, In : British Journal of Pharmacology. 171, 24, p. 5624-5635 12 p.

Research output: Contribution to journalArticle

16 Scopus citations

Soluble toll like receptor 2 (TLR-2) is increased in saliva of children with dental caries

Zhao, A., Blackburn, C., Chin, J. & Srinivasan, M., Aug 31 2014, In : BMC Oral Health. 14, 1, 108.

Research output: Contribution to journalArticle

16 Scopus citations

The effect of intraoral suction on oxygen-enriched surgical environments: A mechanism for reducing the risk of surgical fires

Van Cleave, A. M., Jones, J. E., McGlothlin, J. D., Saxen, M. A., Sanders, B. J. & Vinson, L. A., Dec 1 2014, In : Anesthesia progress. 61, 4, p. 155-161 7 p.

Research output: Contribution to journalArticle

9 Scopus citations

The success of stainless steel crowns placed with the Hall technique :A retrospective study

Ludwig, K. H., Fontana, M., Vinson, L. Q. A., Platt, J. A. & Dean, J. A., Dec 1 2014, In : Journal of the American Dental Association. 145, 12, p. 1248-1253 6 p.

Research output: Contribution to journalArticle

35 Scopus citations
2015

Alternative use of an oral endotracheal tube fastener in a patient with junctional epidermolysis bullosa

Mummert, L., Jones, J. & Christopher, J., Jan 1 2015, In : AANA Journal. 83, 5, p. 326-328 3 p.

Research output: Contribution to journalArticle

Associations between genetic variants and the effect of letrozole and exemestane on bone mass and bone turnover

Oesterreich, S., Henry, N. L., Kidwell, K. M., Van Poznak, C. H., Skaar, T. C., Dantzer, J., Li, L., Hangartner, T. N., Peacock, M., Nguyen, A. T., Rae, J. M., Desta, Z., Philips, S., Storniolo, A. M., Stearns, V., Hayes, D. F. & Flockhart, D. A., Nov 1 2015, In : Breast Cancer Research and Treatment. 154, 2, p. 263-273 11 p.

Research output: Contribution to journalArticle

17 Scopus citations

Cypiripi: Exact genotyping of CYP2D6 using high-throughput sequencing data

Numanagić, I., Malikić, S., Pratt, V. M., Skaar, T. C., Flockhart, D. A. & Sahinalp, S. C., Jun 15 2015, In : Bioinformatics. 31, 12, p. i27-i34

Research output: Contribution to journalArticle

18 Scopus citations

Design and synthesis of norendoxifen analogues with dual aromatase inhibitory and estrogen receptor modulatory activities

Lv, W., Liu, J., Skaar, T. C., Flockhart, D. A. & Cushman, M., Mar 26 2015, In : Journal of Medicinal Chemistry. 58, 6, p. 2623-2648 26 p.

Research output: Contribution to journalArticle

22 Scopus citations

Effect of human milk and its components on streptococcus mutans biofilm formation

Allison, L. M., Walker, L. A., Sanders, B. J., Yang, Z., Eckert, G. & Gregory, R. L., 2015, In : Journal of Clinical Pediatric Dentistry. 39, 3, p. 255-261 7 p.

Research output: Contribution to journalArticle

14 Scopus citations

Estrogens and their precursors in postmenopausal women with early breast cancer receiving anastrozole

Ingle, J. N., Kalari, K. R., Buzdar, A. U., Robson, M. E., Goetz, M. P., Desta, Z., Barman, P., Dudenkov, T. T., Northfelt, D. W., Perez, E. A., Flockhart, D. A., Williard, C. V., Wang, L. & Weinshilboum, R. M., May 26 2015, In : Steroids. 99, Part A, p. 32-38 7 p.

Research output: Contribution to journalArticle

25 Scopus citations

In vivo assessment of the metabolic activity of CYP2D6 diplotypes and alleles

Hertz, D. L., Snavely, A. C., McLeod, H. L., Walko, C. M., Ibrahim, J. G., Anderson, S., Weck, K. E., Magrinat, G., Olajide, O., Moore, S., Raab, R., Carrizosa, D. R., Corso, S., Schwartz, G., Peppercorn, J. M., Evans, J. P., Jones, D. R., Desta, Z., Flockhart, D. A., Carey, L. A. & 1 others, Irvin, W. J., Nov 1 2015, In : British Journal of Clinical Pharmacology. 80, 5, p. 1122-1130 9 p.

Research output: Contribution to journalArticle

27 Scopus citations

Native language spoken as a risk marker for tooth decay

Carson, J., Walker, L. A., Sanders, B. J., Jones, J. E., Weddell, J. A. & Tomlin, A. M., 2015, In : Journal of Clinical Pediatric Dentistry. 39, 5, p. 415-418 4 p.

Research output: Contribution to journalArticle

Platelet factor XIIIa release during platelet aggregation and plasma clot strength measured by thrombelastography in patients with coronary artery disease treated with clopidogrel

Kreutz, R. P., Owens, J., Lu, D., Nystrom, P., Jin, Y., Kreutz, Y., Desta, Z. & Flockhart, D. A., Jun 1 2015, In : Platelets. 26, 4, p. 358-363 6 p.

Research output: Contribution to journalArticle

6 Scopus citations
2016

Clinical benefit of a precision medicine based approach for guiding treatment of refractory cancers

Radovich, M., Kiel, P. J., Nance, S. M., Niland, E. E., Parsley, M. E., Ferguson, M. E., Jiang, G., Ammakkanavar, N. R., Einhorn, L. H., Cheng, L., Nassiri, M., Davidson, D. D., Rushing, D. A., Loehrer, P. J., Pili, R., Hanna, N., Thomas Callaghan, J., Skaar, T. C., Helft, P. R., Shahda, S. & 2 others, O'Neil, B. H. & Schneider, B. P., 2016, In : Oncotarget. 7, 35, p. 56491-56500 10 p.

Research output: Contribution to journalArticle

38 Scopus citations

Radiation Safety and Protection in Pediatric Dentistry: Rectangular Collimation

Yepes, J. F., Mar 1 2016, In : Journal (Indiana Dental Association). 95, 2, p. 24-27 4 p.

Research output: Contribution to journalArticle

SARC009: Phase 2 study of dasatinib in patients with previously treated, high-grade, advanced sarcoma

Schuetze, S. M., Wathen, J. K., Lucas, D. R., Choy, E., Samuels, B. L., Staddon, A. P., Ganjoo, K. N., Von Mehren, M., Chow, W. A., Loeb, D. M., Tawbi, H. A., Rushing, D. A., Patel, S. R., Thomas, D. G., Chugh, R., Reinke, D. K. & Baker, L. H., Mar 15 2016, In : Cancer. 122, 6, p. 868-874 7 p.

Research output: Contribution to journalArticle

43 Scopus citations
2017

Comparison of anesthesia for dental/oral surgery by office-based dentist anesthesiologists versus operating room-based physician anesthesiologists

Saxen, M. A., Urman, R. D., Yepes, J. F., Gabriel, R. A. & Jones, J. E., Dec 1 2017, In : Anesthesia progress. 64, 4, p. 212-220 9 p.

Research output: Contribution to journalArticle

2 Scopus citations

Effect of commonly prescribed liquid medications on streptococcus mutans biofilm. An in vitro study

Clark, S. A., Vinson, L. A., Eckert, G. & Gregory, R. L., 2017, In : Journal of Clinical Pediatric Dentistry. 41, 2, p. 141-146 6 p.

Research output: Contribution to journalArticle

4 Scopus citations

Fluoride in the diet of 2-years-old children

Martinez-Mier, E. A., Spencer, K. L., Sanders, B. J., Jones, J. E., Soto-Rojas, A. E., Tomlin, A. M., Vinson, L. Q. A., Weddell, J. A. & Eckert, G. J., Jun 1 2017, In : Community Dentistry and Oral Epidemiology. 45, 3, p. 251-257 7 p.

Research output: Contribution to journalArticle

3 Scopus citations

In vitro effects of sports and energy drinks on streptococcus mutans biofilm formation and metabolic activity

Vinson, L. A., Goodlett, A. K., Huang, R., Eckert, G. J. & Gregory, R. L., Sep 1 2017, In : Journal of Dentistry for Children. 84, 3, p. 108-114 7 p.

Research output: Contribution to journalArticle