Medical & Molecular Genetics

Publications

2014

Next-generation transcriptome sequencing of the premenopausal breast epithelium using specimens from a normal human breast tissue bank

Pardo, I., Lillemoe, H. A., Blosser, R. J., Choi, M. R., Sauder, C. A. M., Doxey, D. K., Mathieson, T., Hancock, B. A., Baptiste, D., Atale, R., Hickenbotham, M., Zhu, J., Glasscock, J., Storniolo, A. M. V., Zheng, F., Doerge, RW. W., Liu, Y., Badve, S., Radovich, M. & Clare, S. E., Mar 17 2014, In : Breast Cancer Research. 16, 2, R26.

Research output: Contribution to journalArticle

24 Scopus citations

Novel specific microRNA biomarkers in idiopathic inflammatory bowel disease unrelated to disease activity

Lin, J., Welker, N. C., Zhao, Z., Li, Y., Zhang, J., Reuss, S. A., Zhang, X., Lee, H., Liu, Y. & Bronner, M. P., Apr 2014, In : Modern Pathology. 27, 4, p. 602-608 7 p.

Research output: Contribution to journalArticle

44 Scopus citations

Opposing effects of membrane-anchored CX3CL1 on amyloid and tau pathologies via the p38 MAPK pathway

Lee, S., Xu, G., Jay, T. R., Ransohoff, R. M., Lamb, B. T., Bhatta, S., Landreth, G. E., Kim, K. W. & Jung, S., Sep 10 2014, In : Journal of Neuroscience. 34, 37, p. 12538-12546 9 p.

Research output: Contribution to journalArticle

57 Scopus citations

p53 modulates Hsp90 ATPase activity and regulates aryl hydrocarbon receptor signaling

Kochhar, A., Kopelovich, L., Sue, E., Guttenplan, J. B., Herbert, B. S., Dannenberg, A. J. & Subbaramaiah, K., Jun 2014, In : Cancer Prevention Research. 7, 6, p. 596-606 11 p.

Research output: Contribution to journalArticle

15 Scopus citations

P53 protein regulates Hsp90 atpase activity and thereby wnt signaling by modulating Aha1 expression

Okayama, S., Kopelovich, L., Balmus, G., Weiss, R. S., Herbert, B. S., Dannenberg, A. J. & Subbaramaiah, K., Mar 7 2014, In : Journal of Biological Chemistry. 289, 10, p. 6513-6525 13 p.

Research output: Contribution to journalArticle

26 Scopus citations

Parent-of-origin-specific allelic associations among 106 genomic loci for age at menarche

Perry, J. R. B., Day, F., Elks, C. E., Sulem, P., Thompson, D. J., Ferreira, T., He, C., Chasman, D. I., Esko, T., Thorleifsson, G., Albrecht, E., Ang, W. Q., Corre, T., Cousminer, D. L., Feenstra, B., Franceschini, N., Ganna, A., Johnson, A. D., Kjellqvist, S., Lunetta, K. L. & 178 others, McMahon, G., Nolte, I. M., Paternoster, L., Porcu, E., Smith, A. V., Stolk, L., Teumer, A., Tšernikova, N., Tikkanen, E., Ulivi, S., Wagner, E. K., Amin, N., Bierut, L. J., Byrne, E. M., Hottenga, J. J., Koller, D. L., Mangino, M., Pers, T. H., Yerges-Armstrong, L. M., Zhao, J. H., Andrulis, I. L., Anton-Culver, H., Atsma, F., Bandinelli, S., Beckmann, M. W., Benitez, J., Blomqvist, C., Bojesen, S. E., Bolla, M. K., Bonanni, B., Brauch, H., Brenner, H., Buring, J. E., Chang-Claude, J., Chanock, S., Chen, J., Chenevix-Trench, G., Collée, J. M., Couch, F. J., Couper, D., Coviello, A. D., Cox, A., Czene, K., D'adamo, A. P., Smith, G. D., De Vivo, I., Demerath, E. W., Dennis, J., Devilee, P., Dieffenbach, A. K., Dunning, A. M., Eiriksdottir, G., Eriksson, J. G., Fasching, P. A., Ferrucci, L., Flesch-Janys, D., Flyger, H., Foroud, T., Franke, L., Garcia, M. E., García-Closas, M., Geller, F., De Geus, E. E. J., Giles, G. G., Gudbjartsson, D. F., Gudnason, V., Guénel, P., Guo, S., Hall, P., Hamann, U., Haring, R., Hartman, C. A., Heath, A. C., Hofman, A., Hooning, M. J., Hopper, J. L., Hu, F. B., Hunter, D. J., Karasik, D., Kiel, D. P., Knight, J. A., Kosma, V. M., Kutalik, Z., Lai, S., Lambrechts, D., Lindblom, A., Mägi, R., Magnusson, P. K., Mannermaa, A., Martin, N. G., Masson, G., McArdle, P. F., McArdle, W. L., Melbye, M., Michailidou, K., Mihailov, E., Milani, L., Milne, R. L., Nevanlinna, H., Neven, P., Nohr, E. A., Oldehinkel, A. J., Oostra, B. A., Palotie, A., Peacock, M., Pedersen, N. L., Peterlongo, P., Peto, J., Pharoah, P. D. P., Postma, D. S., Pouta, A., Pylkäs, K., Radice, P., Ring, S., Rivadeneira, F., Robino, A., Rose, L. M., Rudolph, A., Salomaa, V., Sanna, S., Schlessinger, D., Schmidt, M. K., Southey, M. C., Sovio, U., Stampfer, M. J., Stöckl, D., Storniolo, A. M., Timpson, N. J., Tyrer, J., Visser, J. A., Vollenweider, P., Völzke, H., Waeber, G., Waldenberger, M., Wallaschofski, H., Wang, Q., Willemsen, G., Winqvist, R., Wolffenbuttel, B. H. R., Wright, M. J., Boomsma, D. I., Econs, M. J., Khaw, K. T., Loos, R. J. F., McCarthy, M. I., Montgomery, G. W., Rice, J. P., Streeten, E. A., Thorsteinsdottir, U., Van Duijn, C. M., Alizadeh, B. Z., Bergmann, S., Boerwinkle, E., Boyd, H. A., Crisponi, L., Gasparini, P., Gieger, C., Harris, T. B., Ingelsson, E., Järvelin, M. R., Kraft, P., Lawlor, D., Metspalu, A., Pennell, C. E., Ridker, P. M., Snieder, H., Sørensen, T. I. A., Spector, T. D., Strachan, D. P., Uitterlinden, A. G., Wareham, N. J., Widen, E., Zygmunt, M., Murray, A., Easton, D. F., Stefansson, K., Murabito, J. M. & Ong, K. K., Oct 2 2014, In : Nature. 514, 7520, p. 92-97 6 p.

Research output: Contribution to journalArticle

260 Scopus citations

Pharmacoepidemiologic and in vitro evaluation of potential drug-drug interactions of sulfonylureas with fibrates and statins

Schelleman, H., Han, X., Brensinger, C. M., Quinney, S. K., Bilker, W. B., Flockhart, D. A., Li, L. & Hennessy, S., Sep 2014, In : British Journal of Clinical Pharmacology. 78, 3, p. 639-648 10 p.

Research output: Contribution to journalArticle

13 Scopus citations

Phenotypic Dissection of Bone Mineral Density Reveals Skeletal Site Specificity and Facilitates the Identification of Novel Loci in the Genetic Regulation of Bone Mass Attainment

Kemp, J. P., Medina-Gomez, C., Estrada, K., St Pourcain, B., Heppe, D. H. M., Warrington, N. M., Oei, L., Ring, S. M., Kruithof, C. J., Timpson, N. J., Wolber, L. E., Reppe, S., Gautvik, K., Grundberg, E., Ge, B., van der Eerden, B., van de Peppel, J., Hibbs, M. A., Ackert-Bicknell, C. L., Choi, K. & 13 others, Koller, D. L., Econs, M. J., Williams, F. M. K., Foroud, T., Carola Zillikens, M., Ohlsson, C., Hofman, A., Uitterlinden, A. G., Davey Smith, G., Jaddoe, V. W. V., Tobias, J. H., Rivadeneira, F. & Evans, D. M., Jun 2014, In : PLoS Genetics. 10, 6, e1004423.

Research output: Contribution to journalArticle

76 Scopus citations

Phenotypic plasticity in normal breast derived epithelial cells

Sauder, C. A. M., Koziel, J. E., Choi, M. R., Fox, M. J., Grimes, B. R., Badve, S., Blosser, R. J., Radovich, M., Lam, C. C., Vaughan, M. B., Herbert, B. S. & Clare, S. E., Jun 10 2014, In : BMC Cell Biology. 15, 1, 20.

Research output: Contribution to journalArticle

10 Scopus citations

Preclinical demonstration of lentiviral vector-mediated correction of immunological and metabolic abnormalities in models of adenosine deaminase deficiency

Carbonaro, D. A., Zhang, L., Jin, X., Montiel-Equihua, C., Geiger, S., Carmo, M., Cooper, A., Fairbanks, L., Kaufman, M. L., Sebire, N. J., Hollis, R. P., Blundell, M. P., Senadheera, S., Fu, P. Y., Sahaghian, A., Chan, R. Y., Wang, X., Cornetta, K., Thrasher, A. J., Kohn, D. B. & 1 others, Gaspar, H. B., Mar 2014, In : Molecular Therapy. 22, 3, p. 607-622 16 p.

Research output: Contribution to journalArticle

52 Scopus citations

Preclinical safety and efficacy of an anti-HIV-1 lentiviral vector containing a short hairpin RNA to CCR5 and the C46 fusion inhibitor

Wolstein, O., Boyd, M., Millington, M., Impey, H., Boyer, J., Howe, A., Delebecque, F., Cornetta, K., Rothe, M., Baum, C., Nicolson, T., Koldej, R., Zhang, J., Keech, N., Camba Colón, J., Breton, L., Bartlett, J., An, D. S., Chen, I. S., Burke, B. & 1 others, Symonds, G. P., Jan 8 2014, In : Molecular Therapy - Methods and Clinical Development. 1, 1 p., 11.

Research output: Contribution to journalArticle

32 Scopus citations

Prenatal diagnosis of Carpenter syndrome: Looking beyond craniosynostosis and polysyndactyly

Victorine, A. S., Weida, J., Hines, K. A., Robinson, B., Torres-Martinez, W. & Weaver, D. D., Mar 2014, In : American Journal of Medical Genetics, Part A. 164, 3, p. 820-823 4 p.

Research output: Contribution to journalArticle

4 Scopus citations

Recommendations for human epidermal growth factor receptor 2 testing in breast cancer: American society of clinical oncology/college of American pathologists clinical practice guideline update

Wolff, A. C., Hammond, M. E. H., Hicks, D. G., Dowsett, M., McShane, L. M., Allison, K. H., Allred, D. C., Bartlett, J. M. S., Bilous, M., Fitzgibbons, P., Hanna, W., Jenkins, R. B., Mangu, P. B., Paik, S., Perez, E. A., Press, M. F., Spears, P. A., Vance, G. H., Viale, G. & Hayes, D. F., Feb 2014, In : Archives of Pathology and Laboratory Medicine. 138, 2, p. 241-256 16 p.

Research output: Contribution to journalArticle

587 Scopus citations

Resveratrol augments paclitaxel treatment in MDA-MB-231 and paclitaxel-resistant MDA-MB-231 breast cancer cells

Sprouse, A. A. & Herbert, B. S., Oct 1 2014, In : Anticancer Research. 34, 10, p. 5363-5374 12 p.

Research output: Contribution to journalArticle

31 Scopus citations

Role of semaphorin-1a in the developing visual system of the disease vector mosquito Aedes aegypti

Mysore, K., Flannery, E., Leming, M. T., Tomchaney, M., Shi, L., Sun, L., O'Tousa, J. E., Severson, D. W. & Duman-Scheel, M., Nov 1 2014, In : Developmental Dynamics. 243, 11, p. 1457-1469 13 p.

Research output: Contribution to journalArticle

11 Scopus citations

Selective inhibition of pancreatic ductal adenocarcinoma cell growth by the mitotic mps1 kinase inhibitor NMS-P715

Slee, R. B., Grimes, B. R., Bansal, R., Gore, J., Blackburn, C., Brown, L., Gasaway, R., Jeong, J., Victorino, J., March, K. L., Colombo, R., Herbert, B. S. & Korc, M., Feb 2014, In : Molecular cancer therapeutics. 13, 2, p. 307-315 9 p.

Research output: Contribution to journalArticle

28 Scopus citations

Severe vascular calcification and tumoral calcinosis in a family with hyperphosphatemia: A fibroblast growth factor 23 mutation identified by exome sequencing

Shah, A., Miller, C. J., Nast, C. C., Adams, M. D., Truitt, B., Tayek, J. A., Tong, L., Mehtani, P., Monteon, F., Sedor, J. R., Clinkenbeard, E. L., White, K., Mehrotra, R., LaPage, J., Dickson, P., Adler, S. G. & Iyengar, S. K., Dec 1 2014, In : Nephrology Dialysis Transplantation. 29, 12, p. 2235-2243 9 p.

Research output: Contribution to journalArticle

18 Scopus citations

SIBLING family genes and bone mineral density: Association and allele-specific expression in humans

Alam, I., Padgett, L. R., Ichikawa, S., Alkhouli, M., Koller, D. L., Lai, D., Peacock, M., Xuei, X., Foroud, T., Edenberg, H. J. & Econs, M. J., Jul 2014, In : Bone. 64, p. 166-172 7 p.

Research output: Contribution to journalArticle

5 Scopus citations
6 Scopus citations

Sterol regulatory element-binding protein-1 (SREBP-1) is required to regulate glycogen synthesis and gluconeogenic gene expression in mouse liver

Ruiz, R., Jideonwo, V., Ahn, M., Surendran, S., Tagliabracci, V. S., Hou, Y., Gamble, A., Kerner, J., Irimia-Dominguez, J. M., Puchowicz, M. A., DePaoli-Roach, A., Hoppel, C., Roach, P. & Morral, N., Feb 28 2014, In : Journal of Biological Chemistry. 289, 9, p. 5510-5517 8 p.

Research output: Contribution to journalArticle

49 Scopus citations

Survivin-induced abnormal ploidy contributes to cystic kidney and aneurysm formation

Abou Alaiwi, W. A., Muntean, B. S., Ratnam, S., Joe, B., Liu, L., Booth, R. L., Rodriguez, I., Herbert, B. S., Bacallao, R. L., Fruttiger, M., Mak, T. W., Zhou, J. & Nauli, S. M., Feb 11 2014, In : Circulation. 129, 6, p. 660-672 13 p.

Research output: Contribution to journalArticle

26 Scopus citations

Text mining for drug-drug interaction

Wu, H. Y., Chiang, C. W. & Li, L., Jan 1 2014, In : Methods in Molecular Biology. 1159, p. 47-75 29 p.

Research output: Contribution to journalArticle

8 Scopus citations

TGF-β induces global changes in DNA methylation during the epithelial-to-mesenchymal transition in ovarian cancer cells

Cardenas, H., Vieth, E., Lee, J., Segar, M., Liu, Y., Nephew, K. P. & Matei, D., Dec 18 2014, In : Epigenetics. 9, 11, p. 1461-1472 12 p.

Research output: Contribution to journalArticle

71 Scopus citations

The Presence of Telomere Fusion in Sporadic Colon Cancer Independently of Disease Stage, TP53/KRAS Mutation Status, Mean Telomere Length, and Telomerase Activity

Tanaka, H., Beam, M. J. & Caruana, K., Jan 1 2014, In : Neoplasia. 16, 10, p. 814-823 10 p.

Research output: Contribution to journalArticle

12 Scopus citations

Therapy-related myeloid neoplasm with bonemarrow involvement, myelosarcoma, and a t(8;16)(p11.2;p13.3)-a case report

Chakraborty, S., Adams, J., Nassiri, M. & Vance, G. H., Oct 1 2014, In : Cancer Genetics. 207, 10-12, p. 511-515 5 p.

Research output: Contribution to journalArticle

2 Scopus citations

Tracking motor impairments in the progression of Huntington's disease

Long, J. D., Paulsen, J. S., Marder, K., Zhang, Y., Kim, J. I., Mills, J. A., Cross, S., Ryan, P., Epping, E. A., Vik, S., Chiu, E., Preston, J., Goh, A., Antonopoulos, S., Loi, S., Chua, P., Komiti, A., Raymond, L., Decolongon, J., Fan, M. & 78 others, Coleman, A., Ross, C. A., Varvaris, M., Yoritomo, N., Mallonee, W. M., Suter, G., Samii, A., Macaraeg, A., Jones, R., Wood-Siverio, C., Factor, S. A., Barker, R. A., Mason, S., Guzman, N. V., McCusker, E., Griffith, J., Loy, C., Gunn, D., Orth, M., Sübmuth, S., Barth, K., Trautmann, S., Schwenk, D., Eschenbach, C., Quaid, K., Wesson, M., Wojcieszek, J., Guttman, M., Sheinberg, A., Law, A., Perlman, S., Clemente, B., Geschwind, M. D., Sha, S., Satris, G., Warner, T., Burrows, M., Rosser, A., Price, K., Hunt, S., Marshall, F., Chesire, A., Wodarski, M., Hickey, C., Panegyres, P., Lee, J., Tedesco, M., Maxwell, B., Perlmutter, J., Barton, S., Smith, S., Miedzybrodzka, Z., Rae, D., D'Alessandro, M., Craufurd, D., Bek, J., Howard, E., Mazzoni, P., Marder, K., Wasserman, P., Kumar, R., Erickson, D., Nickels, B., Wheelock, V., Kjer, L., Martin, A., Farias, S., Martin, W., King, P., Wieler, M., Sran, S., Suchowersky, O., Ahmed, A., Rao, S., Reece, C., Bura, A., Mourany, L. & Pallai, J., Mar 2014, In : Movement Disorders. 29, 3, p. 311-319 9 p.

Research output: Contribution to journalArticle

29 Scopus citations
4 Scopus citations

Two rare AKAP9 variants are associated with Alzheimer's disease in African Americans

Logue, M. W., Schu, M., Vardarajan, B. N., Farrell, J., Bennett, D. A., Buxbaum, J. D., Byrd, G. S., Ertekin-Taner, N., Evans, D., Foroud, T., Goate, A., Graff-Radford, N. R., Kamboh, M. I., Kukull, W. A., Manly, J. J., Hainesm, J. L., Mayeuxl, R., Pericak-Vancen, M. A., Schellenbergo, G. D., Lunettab, K. L. & 3 others, Baldwina, C. T., Daniele Fallinp, M. & Farrer, L. A., Nov 1 2014, In : Alzheimer's and Dementia. 10, 6, p. 609-618.e11

Research output: Contribution to journalArticle

52 Scopus citations
2013

Activation of CpxRA in Haemophilus ducreyi primarily inhibits the expression of Its targets, including major virulence determinants

Gangaiah, D., Zhang, X., Fortney, K. R., Baker, B., Liu, Y., Munson, R. S. & Spinola, S. M., Aug 1 2013, In : Journal of Bacteriology. 195, 15, p. 3486-3502 17 p.

Research output: Contribution to journalArticle

26 Scopus citations

A genome-wide association study of alcohol-dependence symptom counts in extended pedigrees identifies C15orf53

Wang, J. C., Foroud, T., Hinrichs, A. L., Le, N. X. H., Bertelsen, S., Budde, J. P., Harari, O., Koller, D. L., Wetherill, L., Agrawal, A., Almasy, L., Brooks, A. I., Bucholz, K., Dick, D., Hesselbrock, V., Johnson, E. O., Kang, S., Kapoor, M., Kramer, J., Kuperman, S. & 17 others, Madden, P. A. F., Manz, N., Martin, N. G., McClintick, J. N., Montgomery, G. W., Nurnberger, J. I., Rangaswamy, M., Rice, J., Schuckit, M., Tischfield, J. A., Whitfield, J. B., Xuei, X., Porjesz, B., Heath, A. C., Edenberg, H. J., Bierut, L. J. & Goate, A. M., Nov 1 2013, In : Molecular Psychiatry. 18, 11, p. 1218-1224 7 p.

Research output: Contribution to journalArticle

57 Scopus citations

A meta-analysis of two genome-wide association studies to identify novel loci for maximum number of alcoholic drinks

Kapoor, M., Wang, J. C., Wetherill, L., Le, N., Bertelsen, S., Hinrichs, A. L., Budde, J., Agrawal, A., Bucholz, K., Dick, D., Harari, O., Hesselbrock, V., Kramer, J., Nurnberger, J. I., Rice, J., Saccone, N., Schuckit, M., Tischfield, J., Porjesz, B., Edenberg, H. J. & 3 others, Bierut, L., Foroud, T. & Goate, A., Oct 1 2013, In : Human genetics. 132, 10, p. 1141-1151 11 p.

Research output: Contribution to journalArticle

52 Scopus citations

Amplification of distant estrogen response elements deregulates target genes associated with tamoxifen resistance in breast cancer

Hsu, P. Y., Hsu, H. K., Lan, X., Juan, L., Yan, P. S., Labanowska, J., Heerema, N., Hsiao, T. H., Chiu, Y. C., Chen, Y., Liu, Y., Li, L., Li, R., Thompson, I. M., Nephew, K. P., Sharp, Z. D., Kirma, N. B., Jin, V. X. & Huang, T. H. M., Aug 12 2013, In : Cancer Cell. 24, 2, p. 197-212 16 p.

Research output: Contribution to journalArticle

33 Scopus citations

A new assay for measuring chromosome instability (CIN) and identification of drugs that elevate CIN in cancer cells

Lee, H. S., Lee, N. C. O., Grimes, B. R., Samoshkin, A., Kononenko, A. V., Bansal, R., Masumoto, H., Earnshaw, W. C., Kouprina, N. & Larionov, V., May 22 2013, In : BMC Cancer. 13, 252.

Research output: Contribution to journalArticle

25 Scopus citations

A new method for stranded whole transcriptome RNA-seq

Miller, D. F. B., Yan, P. S., Buechlein, A., Rodriguez, B. A., Yilmaz, A. S., Goel, S., Lin, H., Collins-Burow, B., Rhodes, L. V., Braun, C., Pradeep, S., Rupaimoole, R., Dalkilic, M., Sood, A. K., Burow, M. E., Tang, H., Huang, T. H., Liu, Y., Rusch, D. B. & Nephew, K. P., Sep 15 2013, In : Methods. 63, 2, p. 126-134 9 p.

Research output: Contribution to journalArticle

31 Scopus citations

An integrated pharmacokinetics ontology and corpus for text mining

Wu, H. Y., Karnik, S., Subhadarshini, A., Wang, Z., Philips, S., Han, X., Chiang, C., Liu, L., Boustani, M., Rocha, L. M., Quinney, S. K., Flockhart, D. & Li, L., Feb 1 2013, In : BMC bioinformatics. 14, 1, 35.

Research output: Contribution to journalArticle

26 Scopus citations

A pharmacogenetics study to predict outcome in patients receiving anti-VEGF therapy in age related macular degeneration

Kitchens, J. W., Kassem, N., Wood, W., Stone, T. W., Isernhagen, R., Wood, E., Hancock, B. A., Radovich, M., Waymire, J., Li, L. & Schneider, B. P., Oct 9 2013, In : Clinical Ophthalmology. 7, p. 1987-1993 7 p.

Research output: Contribution to journalArticle

24 Scopus citations

A reporter system for replication-competent gammaretroviruses: the inGluc-MLV-DERSE assay

Aloia, A. L., Duffy, L., Pak, V., Lee, K. E., Sanchez-Martinez, S., Derse, D., Heidecker, G., Cornetta, K. & Rein, A., Feb 1 2013, In : Gene Therapy. 20, 2, p. 169-176 8 p.

Research output: Contribution to journalArticle

6 Scopus citations

Aromatase inhibitor-induced modulation of breast density: Clinical and genetic effects

Henry, N. L., Chan, H. P., Dantzer, J., Goswami, C. P., Li, L., Skaar, T. C., Rae, J. M., Desta, Z., Khouri, N., Pinsky, R., Oesterreich, S., Zhou, C., Hadjiiski, L., Philips, S., Robarge, J., Nguyen, A. T., Storniolo, A. M., Flockhart, D. A., Hayes, D. F., Helvie, M. A. & 1 others, Stearns, V., Oct 29 2013, In : British Journal of Cancer. 109, 9, p. 2331-2339 9 p.

Research output: Contribution to journalArticle

16 Scopus citations

A Telomerase Immortalized Human Proximal Tubule Cell Line with a Truncation Mutation (Q4004X) in Polycystin-1

Herbert, B. S., Grimes, B. R., Xu, W. M., Werner, M., Ward, C., Rossetti, S., Harris, P., Bello-Reuss, E., Ward, H. H., Miller, C., Gattone, V. H., Phillips, C. L., Wandinger-Ness, A. & Bacallao, R. L., Jan 28 2013, In : PloS one. 8, 1, e55191.

Research output: Contribution to journalArticle

9 Scopus citations

Balancing personalized medicine and personalized care

Cornetta, K. & Brown, C. G., Mar 2013, In : Academic Medicine. 88, 3, p. 309-313 5 p.

Research output: Contribution to journalReview article

42 Scopus citations

Biogeography of the ecosystems of the healthy human body

Zhou, Y., Gao, H., Mihindukulasuriya, K. A., Rosa, P. S. L., Wylie, K. M., Vishnivetskaya, T., Podar, M., Warner, B., Tarr, P. I., Nelson, D. E., Fortenberry, J. D., Holland, M. J., Burr, S. E., Shannon, W. D., Sodergren, E. & Weinstock, G. M., Jan 14 2013, In : Genome biology. 14, 1, R1.

Research output: Contribution to journalArticle

116 Scopus citations

Biomedicines-moving biologic agents into approved treatment options

Cornetta, K., Dec 1 2013, In : Biomedicines. 1, 1, p. 1-2 2 p.

Research output: Contribution to journalEditorial

C9orf72 hexanucleotide repeat expansions in clinical alzheimer disease

Harms, M., Benitez, B. A., Cairns, N., Cooper, B., Cooper, P., Mayo, K., Carrell, D., Faber, K., Williamson, J., Bird, T., Diaz-Arrastia, R., Foroud, T. M., Boeve, B. F., Graff-Radford, N. R., Mayeux, R., Chakraverty, S., Goate, A. M. & Cruchaga, C., Jun 2013, In : JAMA Neurology. 70, 6, p. 736-741 6 p.

Research output: Contribution to journalArticle

66 Scopus citations

Characterization of a third generation lentiviral vector pseudotyped with Nipah virus envelope proteins for endothelial cell transduction

Witting, S. R., Vallanda, P. & Gamble, A. L., May 24 2013, In : Gene Therapy. 20, 10, p. 997-1005 9 p.

Research output: Contribution to journalArticle

21 Scopus citations

Combined sequence-based and genetic mapping analysis of complex traits in outbred rats

Baud, A., Hermsen, R., Guryev, V., Stridh, P., Graham, D., McBride, M. W., Foroud, T., Calderari, S., Diez, M., Ockinger, J., Beyeen, A. D., Gillett, A., Abdelmagid, N., Guerreiro-Cacais, A. O., Jagodic, M., Tuncel, J., Norin, U., Beattie, E., Huynh, N., Miller, W. H. & 50 others, Koller, D. L., Alam, I., Falak, S., Osborne-Pellegrin, M., Martinez-Membrives, E., Canete, T., Blazquez, G., Vicens-Costa, E., Mont-Cardona, C., Diaz-Moran, S., Tobena, A., Hummel, O., Zelenika, D., Saar, K., Patone, G., Bauerfeind, A., Bihoreau, M. T., Heinig, M., Lee, Y. A., Rintisch, C., Schulz, H., Wheeler, D. A., Worley, K. C., Muzny, D. M., Gibbs, R. A., Lathrop, M., Lansu, N., Toonen, P., Ruzius, F. P., De Bruijn, E., Hauser, H., Adams, D. J., Keane, T., Atanur, S. S., Aitman, T. J., Flicek, P., Malinauskas, T., Jones, E. Y., Ekman, D., Lopez-Aumatell, R., Dominiczak, A. F., Johannesson, M., Holmdahl, R., Olsson, T., Gauguier, D., Hubner, N., Fernandez-Teruel, A., Cuppen, E., Mott, R. & Flint, J., Jul 2013, In : Nature genetics. 45, 7, p. 767-775 9 p.

Research output: Contribution to journalArticle

102 Scopus citations

Common biological networks underlie genetic risk for alcoholism in African- and European-American populations

Kos, M. Z., Yan, J., Dick, D. M., Agrawal, A., Bucholz, K. K., Rice, J. P., Johnson, E. O., Schuckit, M., Kuperman, S., Kramer, J., Goate, A. M., Tischfield, J. A., Foroud, T., Nurnberger, J., Hesselbrock, V., Porjesz, B., Bierut, L. J., Edenberg, H. J. & Almasy, L., Jul 1 2013, In : Genes, Brain and Behavior. 12, 5, p. 532-542 11 p.

Research output: Contribution to journalArticle

18 Scopus citations

Comprehensive genomic profiling in diabetic nephropathy reveals the predominance of proinflammatory pathways

Kelly, K. J., Liu, Y., Zhang, J., Goswami, C., Lin, H. & Dominguez, J. H., Aug 15 2013, In : Physiological Genomics. 45, 16, p. 710-719 10 p.

Research output: Contribution to journalArticle

13 Scopus citations

COPI transport complexes bind to specific RNAs in neuronal cells

Todd, A. G., Lin, H., Ebert, A. D., Liu, Y. & Androphy, E. J., Feb 1 2013, In : Human molecular genetics. 22, 4, p. 729-736 8 p., dds480.

Research output: Contribution to journalArticle

29 Scopus citations

CpG island shore methylation regulates caveolin-1 expression in breast cancer

Rao, X., Evans, J., Chae, H., Pilrose, J., Kim, S., Yan, P., Huang, R. L., Lai, H. C., Lin, H., Liu, Y., Miller, D., Rhee, J. K., Huang, Y. W., Gu, F., Gray, J. W., Huang, T. M. & Nephew, K. P., Sep 19 2013, In : Oncogene. 32, 38, p. 4519-4528 10 p.

Research output: Contribution to journalArticle

82 Scopus citations

CYP2B6 pharmacogenetics-based in vitro-in vivo extrapolation of efavirenz clearance by physiologically based pharmacokinetic modeling

Xu, C., Quinney, S. K., Guo, Y., Hall, S. D., Li, L. & Desta, Z., Dec 1 2013, In : Drug Metabolism and Disposition. 41, 12, p. 2004-2011 8 p.

Research output: Contribution to journalArticle

19 Scopus citations