Medical & Molecular Genetics

Publications

2005
16 Scopus citations

Lipid modification of GRN163, an N3′→P5′ thio-phosphoramidate oligonucleotide, enhances the potency of telomerase inhibition

Herbert, B. S., Gellert, G. C., Hochreiter, A., Pongracz, K., Wright, W. E., Zielinska, D., Chin, A. C., Harley, C. B., Shay, J. W. & Gryaznov, S. M., Aug 4 2005, In : Oncogene. 24, 33, p. 5262-5268 7 p.

Research output: Contribution to journalArticle

152 Scopus citations

LRRK2: Both a cause and a risk factor for Parkinson disease?

Foroud, T., Sep 13 2005, In : Neurology. 65, 5, p. 664-665 2 p.

Research output: Contribution to journalEditorial

13 Scopus citations

Mice with a severe deficiency in protein C display prothrombotic and proinflammatory phenotypes and compromised maternal reproductive capabilities

Lay, A. J., Liang, Z., Rosen, E. D. & Castellino, F. J., Jun 2005, In : Journal of Clinical Investigation. 115, 6, p. 1552-1561 10 p.

Research output: Contribution to journalArticle

60 Scopus citations

Multiple mechanisms are implicated in the generation of 5q35 microdeletions in Sotos syndrome

Tatton-Brown, K., Douglas, J., Coleman, K., Baujat, G., Chandler, K., Clarke, A., Collins, A., Davies, S., Faravelli, F., Firth, H., Garrett, C., Hughes, H., Kerr, B., Liebelt, J., Reardon, W., Schaefer, G. B., Splitt, M., Temple, I. K., Waggoner, D., Weaver, D. D. & 5 others, Wilson, L., Cole, T., Cormier-Daire, V., Irrthum, A. & Rahman, N., Apr 2005, In : Journal of Medical Genetics. 42, 4, p. 307-313 7 p.

Research output: Contribution to journalArticle

45 Scopus citations

Mutations that cause osteoglophonic dysplasia define novel roles for FGFR1 in bone elongation

White, K. E., Cabral, J. M., Davis, S. I., Fishburn, T., Evans, W. E., Ichikawa, S., Fields, J., Yu, X., Shaw, N. J., McLellan, N. J., McKeown, C., FitzPatrick, D., Yu, K., Ornitz, D. M. & Econs, M. J., Feb 2005, In : American Journal of Human Genetics. 76, 2, p. 361-367 7 p.

Research output: Contribution to journalArticle

211 Scopus citations

No association of the GABAA receptor genes on chromosome 5 with alcoholism in the collaborative study on the genetics of alcoholism sample

Dick, D. M., Edenberg, H. J., Xuei, X., Goate, A., Hesselbrock, V., Schuckit, M., Crowe, R. & Foroud, T., Jan 5 2005, In : American Journal of Medical Genetics - Neuropsychiatric Genetics. 132 B, 1, p. 24-28 5 p.

Research output: Contribution to journalArticle

29 Scopus citations

Partial trisomy 2q: Report of a patient with dup (2)(q33.1q35)

Sebold, C. D., Romie, S., Szymanska, J., Torres-Martinez, W., Thurston, V., Muesing, C. & Vance, G. H., Apr 1 2005, In : American Journal of Medical Genetics. 134 A, 1, p. 80-83 4 p.

Research output: Contribution to journalArticle

9 Scopus citations
25 Scopus citations

Polymorphisms in the estrogen receptor β (ESR2) gene are associated with bone mineral density in Caucasian men and women

Ichikawa, S., Koller, D. L., Peacock, M., Johnson, M. L., Lai, D., Hui, S. L., Johnston, C. C., Foroud, T. M. & Econs, M. J., Nov 1 2005, In : Journal of Clinical Endocrinology and Metabolism. 90, 11, p. 5921-5927 7 p.

Research output: Contribution to journalArticle

43 Scopus citations

Principal component analysis for predicting transcription-factor binding motifs from array-derived data

Liu, Y., Vincenti, M. P. & Yokota, H., Nov 18 2005, In : BMC bioinformatics. 6, 276.

Research output: Contribution to journalArticle

7 Scopus citations

Product-enhanced reverse transcriptase assay for replication-competent retrovirus and lentivirus detection

Sastry, L., Xu, Y., Duffy, L., Koop, S., Jasti, A., Roehl, H., Jolly, D. & Cornetta, K., Oct 2005, In : Human gene therapy. 16, 10, p. 1227-1236 10 p.

Research output: Contribution to journalArticle

27 Scopus citations

Rapid communication: A novel recessive mutation in fibroblast growth factor-23 causes familial tumoral calcinosis

Larsson, T., Yu, X., Davis, S. I., Draman, M. S., Mooney, S. D., Cullen, M. J. & White, K. E., Apr 2005, In : Journal of Clinical Endocrinology and Metabolism. 90, 4, p. 2424-2427 4 p.

Research output: Contribution to journalArticle

172 Scopus citations

Real-Time PCR: An effective tool for measuring transduction efficiency in human hematopoietic progenitor cells

Villella, A. D., Yao, J., Getty, R. R., Juliar, B. E., Yiannoutsos, C., Hartwell, J. R., Cai, S., Sadat, M. A., Cornetta, K., Williams, D. A. & Pollok, K. E., Mar 2005, In : Molecular Therapy. 11, 3, p. 483-491 9 p.

Research output: Contribution to journalArticle

7 Scopus citations

Regulation of renal calcium receptor gene expression by 1,25-dihydroxyvitamin D3 in genetic hypercalciuric stone-forming rats

Yao, J. J., Bai, S., Karnauskas, A. J., Bushinsky, D. A. & Favus, M. J., Dec 9 2005, In : Journal of the American Society of Nephrology. 16, 5, p. 1300-1308 9 p.

Research output: Contribution to journalArticle

55 Scopus citations

Relationship of age of first drink to child behavioral problems and family psychopathology

Kuperman, S., Chan, G., Kramer, J. R., Bierut, L., Bucholz, K. K., Fox, L., Hesselbrock, V., Numberger, J. I., Reich, T., Reich, W., Schuckit, M. A., Edenberg, H., Connealfy, P. M., Foroud, T., Crowe, R., Porjesz, B., Begleiter, H., Rice, J., Goate, A., Taylor, R. & 2 others, Tischfield, J. & Almasy, L., Oct 2005, In : Alcoholism: Clinical and Experimental Research. 29, 10, p. 1869-1876 8 p.

Research output: Contribution to journalArticle

59 Scopus citations

Retroviral vector production in the National Gene Vector Laboratory at Indiana University

Cornetta, K., Matheson, L. & Ballas, C., Oct 2005, In : Gene Therapy. 12, p. S28-S35

Research output: Contribution to journalArticle

15 Scopus citations

Role of biomarkers in studies of presymptomatic Alzheimer's disease

Morris, J. C., Quaid K, K. A., Holtzman, D. M., Kantarci, K., Kaye, J., Reiman, E. M., Klunk, W. E. & Siemers, E. R., Oct 2005, In : Alzheimer's and Dementia. 1, 2, p. 145-151 7 p.

Research output: Contribution to journalReview article

21 Scopus citations

Sensory neurons from Nf1 haploinsufficient mice exhibit increased excitability

Wang, Y., Nicol, G. D., Clapp, D. W. & Hingtgen, C. M., Dec 2005, In : Journal of Neurophysiology. 94, 6, p. 3670-3676 7 p.

Research output: Contribution to journalArticle

27 Scopus citations

Sex-specific and non-sex-specific quantitative trait loci contribute to normal variation in bone mineral density in men

Peacock, M., Koller, D. L., Fishburn, T., Krishnan, S., Lai, D., Hui, S., Johnston, C. C., Foroud, T. & Econs, M. J., May 2005, In : Journal of Clinical Endocrinology and Metabolism. 90, 5, p. 3060-3066 7 p.

Research output: Contribution to journalArticle

60 Scopus citations

Sex-specific quantitative trait loci contribute to normal variation in bone structure at the proximal femur in men

Peacock, M., Koller, D. L., Lai, D., Hui, S., Foroud, T. & Econs, M. J., Oct 2005, In : Bone. 37, 4, p. 467-473 7 p.

Research output: Contribution to journalArticle

32 Scopus citations

Standard linkage and association methods identify the mechanism of four susceptibility genes for a simulated complex disease

Pankratz, N., Edenberg, E. & Foroud, T., Dec 30 2005, In : BMC genetics. 6, SUPPL.1, S142.

Research output: Contribution to journalArticle

1 Scopus citations

Telomere dysfunction in aging and cancer

Gilley, D., Tanaka, H. & Herbert, B. S., May 2005, In : International Journal of Biochemistry and Cell Biology. 37, 5 SPEC. ISS., p. 1000-1013 14 p.

Research output: Contribution to journalReview article

68 Scopus citations

The C. elegans Frizzled CFZ-2 is required for cell migration and interacts with multiple Wnt signaling pathways

Zinovyeva, A. Y. & Forrester, W. C., Sep 15 2005, In : Developmental Biology. 285, 2, p. 447-461 15 p.

Research output: Contribution to journalArticle

41 Scopus citations

The Familial Intracranial Aneurysm (FIA) study protocol

Broderick, J. P., Sauerbeck, L. R., Foroud, T., Huston, J., Pankratz, N., Meissner, I. & Brown, R. D., Apr 26 2005, In : BMC Medical Genetics. 6, 17.

Research output: Contribution to journalArticle

50 Scopus citations

The North American Multiple System Atrophy Study Group

Gilman, S., May, S. J., Shults, C. W., Tanner, C. M., Kukull, W., Lee, V. M. Y., Masliah, E., Low, P., Sandroni, P., Trojanowski, J. Q., Ozelius, L. & Foroud, T., Dec 2005, In : Journal of Neural Transmission. 112, 12, p. 1687-1694 8 p.

Research output: Contribution to journalArticle

57 Scopus citations

The Ter mutation in the dead end gene causes germ cell loss and testicular germ cell tumours

Youngren, K. K., Coveney, D., Peng, X., Bhattacharya, C., Schmidt, L. S., Nickerson, M. L., Lamb, B. T., Deng, J. M., Behringer, R. R., Capel, B., Rubin, E. M., Nadeau, J. H. & Matin, A., May 19 2005, In : Nature. 435, 7040, p. 360-364 5 p.

Research output: Contribution to journalArticle

254 Scopus citations

Time-resolved electrometric and optical studies on cytochrome bd suggest a mechanism of electron-proton coupling in the di-heme active site

Belevich, I., Borisov, V. B., Zhang, J., Yang, K., Konstantinov, A. A., Gennis, R. B. & Verkhovsky, M. I., Mar 8 2005, In : Proceedings of the National Academy of Sciences of the United States of America. 102, 10, p. 3657-3662 6 p.

Research output: Contribution to journalArticle

52 Scopus citations

Tissue distribution of fetal liver cells following in utero transplantation in mice

Suckow, M. A., Zollman, A., Cornelissen, I., Casad, M., Roahrig, J., Castellino, F. J. & Rosen, E. D., Dec 2005, In : Experimental Biology and Medicine. 230, 11, p. 860-864 5 p.

Research output: Contribution to journalArticle

2 Scopus citations

Umbilical cord blood transplantation in adults: Results of the prospective cord blood transplantation (COBLT)

Cornetta, K., Laughlin, M., Carter, S., Wall, D., Weinthal, J., Delaney, C., Wagner, J., Sweetman, R., McCarthy, P. & Chao, N., Feb 1 2005, In : Biology of Blood and Marrow Transplantation. 11, 2, p. 149-160 12 p.

Research output: Contribution to journalArticle

113 Scopus citations

Unrelated patients with a rearrangement of chromosome 2 causing duplication of 2p23 and deletion of 2q37

Armstrong, L., Allanson, J. E., Weaver, D. D., Bevan, C. J. & Hobart, H. H., Apr 30 2005, In : American Journal of Medical Genetics. 134 A, 3, p. 299-304 6 p.

Research output: Contribution to journalArticle

3 Scopus citations

Vascular-type disruptive defects in fetuses with homozygous α-thalassemia: Report of two cases and review of the literature

Adam, M. P., Chueh, J., El-Sayed, Y. Y., Stenzel, A., Vogel, H., Weaver, D. D. & Hoyme, H. E., Dec 1 2005, In : Prenatal Diagnosis. 25, 12, p. 1088-1096 9 p.

Research output: Contribution to journalArticle

17 Scopus citations

Whole-genome scan for linkage to bone strength and structure in inbred Fischer 344 and Lewis rats

Alam, I., Sun, Q., Liu, L., Koller, D. L., Fishburn, T., Carr, L. G., Econs, M. J., Foroud, T. & Turner, C. H., Sep 2005, In : Journal of Bone and Mineral Research. 20, 9, p. 1589-1596 8 p.

Research output: Contribution to journalArticle

28 Scopus citations
2004

Aberrant expression of CARM1, a transcriptional coactivator of androgen receptor, in the development of prostate carcinoma and androgen-independent status

Hong, H., Kao, C., Jeng, M. H., Eble, J. N., Koch, M. O., Gardner, T. A., Zhang, S., Li, L., Pan, C. X., Hu, Z., MacLennan, G. T. & Cheng, L., Jul 1 2004, In : Cancer. 101, 1, p. 83-89 7 p.

Research output: Contribution to journalArticle

138 Scopus citations

A genome-wide screen for genes influencing conduct disorder

Dick, D. M., Li, T. K., Edenberg, H. J., Hesselbrock, V., Kramer, J., Kuperman, S., Porjesz, B., Bucholz, K., Goate, A., Nurnberger, J. & Foroud, T., Feb 17 2004, In : Molecular Psychiatry. 9, 1, p. 81-86 6 p.

Research output: Contribution to journalArticle

73 Scopus citations

A Genomic Scan for Habitual Smoking in Families of Alcoholics: Common and Specific Genetic Factors in Substance Dependence

Bierut, L. J., Rice, J. P., Goate, A., Hinrichs, A. L., Saccone, N. L., Foroud, T., Edenberg, H. J., Cloninger, C. R., Begleiter, H., Conneally, P. M., Crowe, R. R., Hesselbrock, V., Li, T. K., Nurnberger, J. I., Porjesz, B., Schuckit, M. A. & Reich, T., Jan 1 2004, In : American Journal of Medical Genetics. 124 A, 1, p. 19-27 9 p.

Research output: Contribution to journalArticle

Open Access
100 Scopus citations

Altered amyloid-β metabolism and deposition in genomic-based β-secretaee transgenic mice

Chiocco, M. J., Kulnane, L. S., Younkin, L., Younkin, S., Evin, G. & Lamb, B. T., Dec 10 2004, In : Journal of Biological Chemistry. 279, 50, p. 52535-52542 8 p.

Research output: Contribution to journalArticle

34 Scopus citations

A population pharmacokinetic model with time-dependent covariates measured with errors

Li, L., Lin, X., Brown, M. B., Gupta, S. & Lee, K. H., Jun 2004, In : Biometrics. 60, 2, p. 451-460 10 p.

Research output: Contribution to journalArticle

9 Scopus citations

Association of GABRG3 with Alcohol Dependence

Dick, D. M., Edenberg, H. J., Xuei, X., Goate, A., Kuperman, S., Schuckit, M., Crowe, R., Smith, T. L., Porjesz, B., Begleiter, H. & Foroud, T., Jan 2004, In : Alcoholism: Clinical and Experimental Research. 28, 1, p. 4-9 6 p.

Research output: Contribution to journalArticle

114 Scopus citations

Cell-type-specific responses to chemotherapeutics in breast cancer

Troester, M. A., Hoadley, K. A., Sørlie, T., Herbert, B. S., Børresen-Dale, A. L., Lønning, P. E., Shay, J. W., Kaufmann, W. K. & Perou, C. M., Jun 15 2004, In : Cancer Research. 64, 12, p. 4218-4226 9 p.

Research output: Contribution to journalArticle

146 Scopus citations

Characterization of gains, losses, and regional amplification in testicular germ cell tumor cell lines by comparative genomic hybridization

Henegariu, O., Heerema, N. A., Thurston, V., Jung, S. H., Pera, M. & Vance, G. H., Jan 1 2004, In : Cancer Genetics and Cytogenetics. 148, 1, p. 14-20 7 p.

Research output: Contribution to journalArticle

15 Scopus citations

Clinical and cytogenetic manifestations of subtelomeric aberrations: Report of six cases

Font-Montgomery, E., Weaver, D. D., Walsh, L., Christensen, C. & Thurston, V. C., Jun 1 2004, In : Birth Defects Research Part A - Clinical and Molecular Teratology. 70, 6, p. 408-415 8 p.

Research output: Contribution to journalArticle

11 Scopus citations

Confirmation of Linkage to Chromosome 1q for Peak Vertebral Bone Mineral Density in Premenopausal White Women

Econs, M. J., Koller, D. L., Hui, S. L., Fishburn, T., Conneally, P. M., Johnston, C. C., Peacock, M. & Foroud, T. M., Feb 2004, In : American Journal of Human Genetics. 74, 2, p. 223-228 6 p.

Research output: Contribution to journalArticle

47 Scopus citations

Different DNA lesions trigger distinct cell death responses in HCT116 colon carcinoma cells

Bai, S. & Goodrich, D. W., May 2004, In : Molecular cancer therapeutics. 3, 5, p. 613-619 7 p.

Research output: Contribution to journalArticle

9 Scopus citations

Disclosure of genetic information obtained through research

Quaid, K. A., Jessup, N. M. & Meslin, E. M., Jan 1 2004, In : Genetic Testing. 8, 3, p. 347-355 9 p.

Research output: Contribution to journalReview article

26 Scopus citations

Disparate effects of telomere attrition on gene expression during replicative senescence of human mammary epithelial cells cultured under different conditions

Zhang, H., Herbert, B. S., Pan, K. H., Shay, J. W. & Cohen, S. N., Aug 19 2004, In : Oncogene. 23, 37, p. 6193-6198 6 p.

Research output: Contribution to journalArticle

25 Scopus citations

Effects of high-impact mechanical loading on synovial cell cultures

Sun, I., Liu, Y., Tanaka, S. M., Lee, C. W., Sun, H. B. & Yokota, H., Dec 1 2004, In : Journal of Sports Science and Medicine. 3, 1, p. 37-43 7 p.

Research output: Contribution to journalArticle

2 Scopus citations

Ethical issues in the collection, storage, and research use of human biological materials

Meslin, E. M. & Quaid, K. A., Nov 1 2004, In : Journal of Laboratory and Clinical Medicine. 144, 5, p. 229-234 6 p.

Research output: Contribution to journalReview article

43 Scopus citations

Evaluation of Plasmid DNA Removal from Lentiviral Vectors by Benzonase Treatment

Sastry, L., Xu, Y., Cooper, R., Pollok, K. & Cornetta, K., Feb 1 2004, In : Human gene therapy. 15, 2, p. 221-226 6 p.

Research output: Contribution to journalArticle

49 Scopus citations

Evaluation of the role of Nurr1 in a large sample of familial Parkinson's disease

Nichols, W. C., Uniacke, S. K., Pankratz, N., Reed, T., Simon, D. K., Halter, C., Rudolph, A., Shults, C. W., Conneally, P. M., Foroud, T., Wojcieszek, J., Belden, J., Carter, J., Camicioli, R., Andrews, P., Panisset, M., Hall, J., Hubble, J., Fernandez, M., Reider, C. & 79 others, Rajput, A., Rajput, A., Shirley, T., Mendis, T., Grimes, D. A., Gray, P., Ramos, C. S., Roque, S., Pfeiffer, R., Pfeiffer, B., Elmer, L., Davis, K., Friedman, J., Fernandez, H., Lannon, M., Reich, S., Dunlop, B., Seeberger, L., O'Brien, C., Judd, D., Hauser, R., Zesiewicz, T., Delgado, H., Shults, C., Fontaine, D., Jennings, D., Marek, K., Mendick, S., Aminoff, M., DiMinno, M., Lewitt, P., DeAngelis, M., Pahwa, R., Thomas, S., Truong, D., Pathak, M., Tran, A., Rodnitzky, R., Dobson, J., Koller, W., Weiner, W., Lyons, K., Kurlan, R., Berry, D., Bertoni, J., Peterson, C., Martin, W., Tuite, P., Schacherer, R., Marder, K., Harris, J., Jankovic, J., Hunter, C., Lang, A., Kleimer-Fisman, G., Nieves, A., So, J., Factor, S., Evans, S., Manyam, B., Wulbrecht, B., Walker, F., Hunt, V., Gordon, M. F., Hamman, J., Kang, U. J., Young, J., Blindauer, K., Petit, J., Rao, J., Cook, M., Stacy, M., Williamson, K., Pullman, R. S., Boyar, K., Leehey, M., Derian, T., Gordon, P. & Werner, J., Jun 2004, In : Movement Disorders. 19, 6, p. 649-655 7 p.

Research output: Contribution to journalArticle

32 Scopus citations