Medical & Molecular Genetics

Publications

2017

Complete Transcriptome RNA-Seq

Miller, D. F. B., Yan, P., Fang, F., Buechlein, A., Kroll, K., Frankhouser, D., Stump, C., Stump, P., Ford, J. B., Tang, H., Michaels, S., Matei, D., Huang, T. H., Chien, J., Liu, Y., Rusch, D. B. & Nephew, K. P., Jan 1 2017, Methods in Molecular Biology. Humana Press Inc., p. 141-162 22 p. (Methods in Molecular Biology; vol. 1513).

Research output: Chapter in Book/Report/Conference proceedingChapter

1 Scopus citations

C-terminal but not intact fibroblast growth factor 23 levels

Knab, V. M., Corbin, B., Andrukhova, O., Hum, J. M., Ni, P., Rabadi, S., Maeda, A., White, K., Erben, R. G., Jüppner, H. & Christov, M., May 1 2017, In : Endocrinology. 158, 5, p. 1130-1139 10 p.

Research output: Contribution to journalArticle

13 Scopus citations

Decreased body mass index in the preclinical stage of autosomal dominant Alzheimer's disease

Müller, S., Preische, O., Sohrabi, H. R., Gräber, S., Jucker, M., Dietzsch, J., Ringman, J. M., Martins, R. N., McDade, E., Schofield, P. R., Ghetti, B., Rossor, M., Graff-Radford, N. R., Levin, J., Galasko, D., Quaid, K. A., Salloway, S., Xiong, C., Benzinger, T., Buckles, V. & 5 others, Masters, C. L., Sperling, R., Bateman, R. J., Morris, J. C. & Laske, C., Dec 1 2017, In : Scientific reports. 7, 1, 1225.

Research output: Contribution to journalArticle

13 Scopus citations

Disease progression-dependent effects of TREM2 deficiency in a mouse model of Alzheimer's disease

Jay, T. R., Hirsch, A. M., Broihier, M. L., Miller, C. M., Neilson, L. E., Ransohoff, R. M., Lamb, B. T. & Landreth, G. E., Jan 18 2017, In : Journal of Neuroscience. 37, 3, p. 637-647 11 p.

Research output: Contribution to journalArticle

Open Access
137 Scopus citations

Editorial

Ruan, J., Huang, K., Zhao, Z. & Liu, Y., Jan 1 2017, In : International Journal of Computational Biology and Drug Design. 10, 2, p. 87-90 4 p.

Research output: Contribution to journalEditorial

Effects of exemestane and letrozole therapy on plasma concentrations of estrogens in a randomized trial of postmenopausal women with breast cancer

Robarge, J. D., Desta, Z., Nguyen, A. T., Li, L., Hertz, D., Rae, J. M., Hayes, D. F., Storniolo, A. M., Stearns, V., Flockhart, D. A., Skaar, T. C. & Henry, N. L., Feb 1 2017, In : Breast Cancer Research and Treatment. 161, 3, p. 453-461 9 p.

Research output: Contribution to journalArticle

7 Scopus citations

Erythropoietin stimulates murine and human fibroblast growth factor-23, revealing novel roles for bone and bone marrow

Clinkenbeard, E. L., Hanudel, M. R., Stayrook, K. R., Appaiah, H. N., Farrow, E. G., Cass, T. A., Summers, L. J., Ip, C. S., Hum, J. M., Thomas, J. C., Ivan, M., Richine, B. M., Chan, R. J., Clemens, T. L., Schipani, E., Sabbagh, Y., Xu, L., Srour, E. F., Alvarez, M. B., Kacena, M. A. & 4 others, Salusky, I. B., Ganz, T., Nemeth, E. & White, K. E., Oct 27 2017, In : Haematologica. 102, 11, p. e427-e430

Research output: Contribution to journalLetter

35 Scopus citations

Evidence for three genetic loci involved in both anorexia nervosa risk and variation of body mass index

Children's Hospital of Philadelphia/Price Foundation, GCAN, WTCCC3, GIANT, EGG & Price Foundation Collaborative Group, Feb 1 2017, In : Molecular Psychiatry. 22, 2, p. 192-201 10 p.

Research output: Contribution to journalArticle

28 Scopus citations

Exome Sequencing Identifies Candidate Genetic Modifiers of Syndromic and Familial Thoracic Aortic Aneurysm Severity

Landis, B. J., Schubert, J. A., Lai, D., Jegga, A. G., Shikany, A. R., Foroud, T., Ware, S. M. & Hinton, R. B., Aug 1 2017, In : Journal of cardiovascular translational research. 10, 4, p. 423-432 10 p.

Research output: Contribution to journalArticle

7 Scopus citations

ExonImpact: Prioritizing Pathogenic Alternative Splicing Events

Li, M., Feng, W., Zhang, X., Yang, Y., Wang, K., Mort, M., Cooper, D. N., Wang, Y., Zhou, Y. & Liu, Y., Jan 1 2017, In : Human Mutation. 38, 1, p. 16-24 9 p.

Research output: Contribution to journalArticle

8 Scopus citations

Expression quantitative locus mapping for identification of hotspots using an empirical Bayes mixture model

Jiang, G., Fu, Y., Zhang, P., Ardeshir-Rouhani-Fard, S., Cheng, L., Li, L. & Li, Z., Jan 1 2017, In : International Journal of Computational Biology and Drug Design. 10, 2, p. 108-122 15 p.

Research output: Contribution to journalArticle

EZH2 modifies sunitinib resistance in renal cell carcinoma by kinome reprogramming

Adelaiye-Ogala, R., Budka, J., Damayanti, N. P., Arrington, J., Ferris, M., Hsu, C. C., Chintala, S., Orillion, A., Miles, K. M., Shen, L., Elbanna, M., Ciamporcero, E., Arisa, S., Pettazzoni, P., Draetta, G. F., Seshadri, M., Hancock, B., Radovich, M., Kota, J., Buck, M. & 9 others, Keilhack, H., McCarthy, B. P., Persohn, S. A., Territo, P. R., Zang, Y., Irudayaraj, J., Tao, W. A., Hollenhorst, P. & Pili, R., Dec 1 2017, In : Cancer Research. 77, 23, p. 6651-6666 16 p.

Research output: Contribution to journalArticle

18 Scopus citations

Facial Curvature Detects and Explicates Ethnic Differences in Effects of Prenatal Alcohol Exposure

the CIFASD, Aug 2017, In : Alcoholism: Clinical and Experimental Research. 41, 8, p. 1471-1483 13 p.

Research output: Contribution to journalArticle

8 Scopus citations

Factors related to genetic testing in adults at risk for Huntington disease: the prospective Huntington at-risk observational study (PHAROS)

Quaid, K. A., Eberly, S. W., Kayson-Rubin, E., Oakes, D., Shoulson, I. & on behalf of the Huntington Study Group PHAROS Investigators and Coordinators, Jun 1 2017, In : Clinical Genetics. 91, 6, p. 824-831 8 p.

Research output: Contribution to journalArticle

6 Scopus citations

Gene therapy for age-related macular degeneration

Moore, N. A., Bracha, P., Hussain, R. M., Morral, N. & Ciulla, T. A., Oct 3 2017, In : Expert Opinion on Biological Therapy. 17, 10, p. 1235-1244 10 p.

Research output: Contribution to journalReview article

16 Scopus citations

Genetic Overlap Between Attention-Deficit/Hyperactivity Disorder and Bipolar Disorder: Evidence From Genome-wide Association Study Meta-analysis

PGC ADHD Working Group & PGC Bipolar Disorder Working Group, Nov 1 2017, In : Biological psychiatry. 82, 9, p. 634-641 8 p.

Research output: Contribution to journalArticle

32 Scopus citations

Genome-wide association study for anthracycline-induced congestive heart failure

Schneider, B. P., Shen, F., Gardner, L., Radovich, M., Li, L., Miller, K. D., Jiang, G., Lai, D., O'Neill, A., Sparano, J. A., Davidson, N. E., Cameron, D., Gradus-Pizlo, I., Mastouri, R. A., Suter, T. M., Foroud, T. & Sledge, G. W., Jan 1 2017, In : Clinical Cancer Research. 23, 1, p. 43-51 9 p.

Research output: Contribution to journalArticle

19 Scopus citations

Genomewide Association Study of Alcohol Dependence Identifies Risk Loci Altering Ethanol-Response Behaviors in Model Organisms

Collaborative Study of the Genetics of Alcoholism Consortium & the German Study of the Genetics of Addiction Consortium, May 2017, In : Alcoholism: Clinical and Experimental Research. 41, 5, p. 911-928 18 p.

Research output: Contribution to journalArticle

17 Scopus citations

Heritable and acquired disorders of phosphate metabolism: Etiologies involving FGF23 and current therapeutics

Clinkenbeard, E. L. & White, K. E., Sep 2017, In : Bone. 102, p. 31-39 9 p.

Research output: Contribution to journalArticle

9 Scopus citations

Impact of genetic ancestry on outcomes in ECOG-ACRIN-5103

Schneider, B. P., Shen, F., Jiang, G., O'Neill, A., Radovich, M., Li, L., Gardner, L., Lai, D., Foroud, T., Sparano, J. A., Sledge, G. W. & Miller, K. D., Jan 1 2017, In : JCO Precision Oncology. 2017, 1, p. 1-9 9 p.

Research output: Contribution to journalArticle

3 Scopus citations
12 Scopus citations

Individualized breast cancer characterization through single-cell analysis of tumor and adjacent normal cells

Anjanappa, M., Cardoso, A., Cheng, L., Mohamad, S., Gunawan, A., Rice, S., Dong, Y., Li, L., Sandusky, G. E., Srour, E. F. & Nakshatri, H., May 15 2017, In : Cancer Research. 77, 10, p. 2759-2769 11 p.

Research output: Contribution to journalArticle

7 Scopus citations

Inflammatory profile discriminates clinical subtypes in LRRK2-associated Parkinson's disease

Brockmann, K., Schulte, C., Schneiderhan-Marra, N., Apel, A., Pont-Sunyer, C., Vilas, D., Ruiz-Martinez, J., Langkamp, M., Corvol, J. C., Cormier, F., Knorpp, T., Joos, T. O., Bernard, A., Gasser, T., Marras, C., Schüle, B., Aasly, J. O., Foroud, T., Marti-Masso, J. F., Brice, A. & 3 others, Tolosa, E., Berg, D. & Maetzler, W., Feb 1 2017, In : European Journal of Neurology. 24, 2, p. 427-e6

Research output: Contribution to journalArticle

14 Scopus citations

Integrative analysis of histopathological images and genomic data predicts clear cell renal cell carcinoma prognosis

Cheng, J., Zhang, J., Han, Y., Wang, X., Ye, X., Meng, Y., Parwani, A., Han, Z., Feng, Q. & Huang, K., Nov 1 2017, In : Cancer Research. 77, 21, p. e91-e100

Research output: Contribution to journalArticle

17 Scopus citations

Investigating DNA-, RNA-, and protein-based features as a means to discriminate pathogenic synonymous variants

Livingstone, M., Folkman, L., Yang, Y., Zhang, P., Mort, M., Cooper, D. N., Liu, Y., Stantic, B. & Zhou, Y., Oct 2017, In : Human Mutation. 38, 10, p. 1336-1347 12 p.

Research output: Contribution to journalArticle

12 Scopus citations

Lentivirus mediated correction of artemis-deficient severe combined immunodeficiency

Punwani, D., Kawahara, M., Yu, J., Sanford, U., Roy, S., Patel, K., Carbonaro, D. A., Karlen, A. D., Khan, S., Cornetta, K., Rothe, M., Schambach, A., Kohn, D. B., Malech, H. L., McIvor, R. S., Puck, J. M. & Cowan, M. J., Jan 1 2017, In : Human gene therapy. 28, 1, p. 112-124 13 p.

Research output: Contribution to journalArticle

12 Scopus citations

Long-term outcome of NPM1 mutated acute myeloid leukemia: A single-institution experience

Sayar, H., Bashardoust, P., Cripe, L., Chakraborty, S. & Bai, S., Feb 1 2017, In : American Journal of Hematology. 92, 2, p. E17-E18

Research output: Contribution to journalLetter

2 Scopus citations

Lure-And-Kill Yeast Interfering RNA Larvicides Targeting Neural Genes in the Human Disease Vector Mosquito Aedes aegypti

Hapairai, L. K., Mysore, K., Chen, Y., Harper, E. I., Scheel, M. P., Lesnik, A. M., Sun, L., Severson, D. W., Wei, N. & Duman-Scheel, M., Dec 1 2017, In : Scientific reports. 7, 1, 13223.

Research output: Contribution to journalArticle

9 Scopus citations

Methods for microRNA profiling in cancer

Yarlagadda, S., Thota, A., Bansal, R., Kwon, J., Korc, M. & Kota, J., Jan 1 2017, Methods in Pharmacology and Toxicology. Humana Press Inc., p. 97-113 17 p. (Methods in Pharmacology and Toxicology).

Research output: Chapter in Book/Report/Conference proceedingChapter

1 Scopus citations

Neurology Individualized Medicine: When to Use Next-Generation Sequencing Panels

Klein, C. J. & Foroud, T., Feb 1 2017, In : Mayo Clinic Proceedings. 92, 2, p. 292-305 14 p.

Research output: Contribution to journalReview article

21 Scopus citations

Novel functions of circulating Klotho

Hum, J. M., O'Bryan, L., Smith, R. C. & White, K. E., Jul 2017, In : Bone. 100, p. 36-40 5 p.

Research output: Contribution to journalReview article

10 Scopus citations

Novel genetic loci associated with hippocampal volume

Hibar, D. P., Adams, H. H. H., Jahanshad, N., Chauhan, G., Stein, J. L., Hofer, E., Renteria, M. E., Bis, J. C., Arias-Vasquez, A., Ikram, M. K., Desrivières, S., Vernooij, M. W., Abramovic, L., Alhusaini, S., Amin, N., Andersson, M., Arfanakis, K., Aribisala, B. S., Armstrong, N. J., Athanasiu, L. & 312 others, Axelsson, T., Beecham, A. H., Beiser, A., Bernard, M., Blanton, S. H., Bohlken, M. M., Boks, M. P., Bralten, J., Brickman, A. M., Carmichael, O., Chakravarty, M. M., Chen, Q., Ching, C. R. K., Chouraki, V., Cuellar-Partida, G., Crivello, F., Den Braber, A., Doan, N. T., Ehrlich, S., Giddaluru, S., Goldman, A. L., Gottesman, R. F., Grimm, O., Griswold, M. E., Guadalupe, T., Gutman, B. A., Hass, J., Haukvik, U. K., Hoehn, D., Holmes, A. J., Hoogman, M., Janowitz, D., Jia, T., Jørgensen, K. N., Karbalai, N., Kasperaviciute, D., Kim, S., Klein, M., Kraemer, B., Lee, P. H., Liewald, D. C. M., Lopez, L. M., Luciano, M., MacAre, C., Marquand, A. F., Matarin, M., Mather, K. A., Mattheisen, M., McKay, D. R., Milaneschi, Y., Muñoz Maniega, S., Nho, K., Nugent, A. C., Nyquist, P., Loohuis, L. M. O., Oosterlaan, J., Papmeyer, M., Pirpamer, L., Pütz, B., Ramasamy, A., Richards, J. S., Risacher, S. L., Roiz-Santiañez, R., Rommelse, N., Ropele, S., Rose, E. J., Royle, N. A., Rundek, T., Sämann, P. G., Saremi, A., Satizabal, C. L., Schmaal, L., Schork, A. J., Shen, L., Shin, J., Shumskaya, E., Smith, A. V., Sprooten, E., Strike, L. T., Teumer, A., Tordesillas-Gutierrez, D., Toro, R., Trabzuni, D., Trompet, S., Vaidya, D., Van Der Grond, J., Van Der Lee, S. J., Van Der Meer, D., Van Donkelaar, M. M. J., Van Eijk, K. R., Van Erp, T. G. M., Van Rooij, D., Walton, E., Westlye, L. T., Whelan, C. D., Windham, B. G., Winkler, A. M., Wittfeld, K., Woldehawariat, G., Wolf, C., Wolfers, T., Yanek, L. R., Yang, J., Zijdenbos, A., Zwiers, M. P., Agartz, I., Almasy, L., Ames, D., Amouyel, P., Andreassen, O. A., Arepalli, S., Assareh, A. A., Barral, S., Bastin, M. E., Becker, D. M., Becker, J. T., Bennett, D. A., Blangero, J., Van Bokhoven, H., Boomsma, D. I., Brodaty, H., Brouwer, R. M., Brunner, H. G., Buckner, R. L., Buitelaar, J. K., Bulayeva, K. B., Cahn, W., Calhoun, V. D., Cannon, D. M., Cavalleri, G. L., Cheng, C. Y., Cichon, S., Cookson, M. R., Corvin, A., Crespo-Facorro, B., Curran, J. E., Czisch, M., Dale, A. M., Davies, G. E., De Craen, A. J. M., De Geus, E. J. C., De Jager, P. L., De Zubicaray, G. I., Deary, I. J., Debette, S., Decarli, C., Delanty, N., Depondt, C., Destefano, A., Dillman, A., Djurovic, S., Donohoe, G., Drevets, W. C., Duggirala, R., Dyer, T. D., Enzinger, C., Erk, S., Espeseth, T., Fedko, I. O., Fernández, G., Ferrucci, L., Fisher, S. E., Fleischman, D. A., Ford, I., Fornage, M., Foroud, T., Fox, P. T., Francks, C., Fukunaga, M., Gibbs, J. R., Glahn, D. C., Gollub, R. L., Göring, H. H. H., Green, R. C., Gruber, O., Gudnason, V., Guelfi, S., Håberg, A. K., Hansell, N. K., Hardy, J., Hartman, C. A., Hashimoto, R., Hegenscheid, K., Heinz, A., Le Hellard, S., Hernandez, D. G., Heslenfeld, D. J., Ho, B. C., Hoekstra, P. J., Hoffmann, W., Hofman, A., Holsboer, F., Homuth, G., Hosten, N., Hottenga, J. J., Huentelman, M., Pol, H. E. H., Ikeda, M., Jack, C. R., Jenkinson, M., Johnson, R., Jönsson, E. G., Jukema, J. W., Kahn, R. S., Kanai, R., Kloszewska, I., Knopman, D. S., Kochunov, P., Kwok, J. B., Lawrie, S. M., Lemaître, H., Liu, X., Longo, D. L., Lopez, O. L., Lovestone, S., Martinez, O., Martinot, J. L., Mattay, V. S., McDonald, C., McIntosh, A. M., McMahon, F. J., McMahon, K. L., Mecocci, P., Melle, I., Meyer-Lindenberg, A., Mohnke, S., Montgomery, G. W., Morris, D. W., Mosley, T. H., Mühleisen, T. W., Müller-Myhsok, B., Nalls, M. A., Nauck, M., Nichols, T. E., Niessen, W. J., Nöthen, M. M., Nyberg, L., Ohi, K., Olvera, R. L., Ophoff, R. A., Pandolfo, M., Paus, T., Pausova, Z., Penninx, B. W. J. H., Pike, G. B., Potkin, S. G., Psaty, B. M., Reppermund, S., Rietschel, M., Roffman, J. L., Romanczuk-Seiferth, N., Rotter, J. I., Ryten, M., Sacco, R. L., Sachdev, P. S., Saykin, A., Schmidt, R., Schmidt, H., Schofield, P. R., Sigursson, S., Simmons, A., Singleton, A., Sisodiya, S. M., Smith, C., Smoller, J. W., Soininen, H., Steen, V. M., Stott, D. J., Sussmann, J. E., Thalamuthu, A., Toga, A. W., Traynor, B. J., Troncoso, J., Tsolaki, M., Tzourio, C., Uitterlinden, A. G., Hernández, M. C. V., Van Der Brug, M., Van Der Lugt, A., Van Der Wee, N. J. A., Van Haren, N. E. M., Van 'T Ent, D., Van Tol, M. J., Vardarajan, B. N., Vellas, B., Veltman, D. J., Völzke, H., Walter, H., Wardlaw, J. M., Wassink, T. H., Weale, M. E., Weinberger, D. R., Weiner, M. W., Wen, W., Westman, E., White, T., Wong, T. Y., Wright, C. B., Zielke, R. H., Zonderman, A. B., Martin, N. G., Van Duijn, C. M., Wright, M. J., Longstreth, W. T., Schumann, G., Grabe, H. J., Franke, B., Launer, L. J., Medland, S. E., Seshadri, S., Thompson, P. M. & Ikram, M. A., Jan 18 2017, In : Nature communications. 8, 13624.

Research output: Contribution to journalArticle

84 Scopus citations

Novel serine 176 phosphorylation of YBX1 activates NF-κB in colon cancer

Martin, M., Hua, L., Wang, B., Wei, H., Prabhu, L., Hartley, A. V., Jiang, G., Liu, Y. & Lu, T., Feb 24 2017, In : Journal of Biological Chemistry. 292, 8, p. 3433-3444 12 p.

Research output: Contribution to journalArticle

14 Scopus citations

Pancreatic cancer: Stroma and its current and emerging targeted therapies

Kota, J., Hancock, J., Kwon, J. & Korc, M., Apr 10 2017, In : Cancer Letters. 391, p. 38-49 12 p.

Research output: Contribution to journalShort survey

52 Scopus citations

Parkinson's disease biomarkers: Perspective from the NINDS Parkinson's Disease Biomarkers Program

Gwinn, K., David, K. K., Swanson-Fischer, C., Albin, R., Hillaire-Clarke, C. S., Sieber, B. A., Lungu, C., Bowman, F. D., Alcalay, R. N., Babcock, D., Dawson, T. M., Dewey, R. B., Foroud, T., German, D., Huang, X., Petyuk, V., Potashkin, J. A., Saunders-Pullman, R., Sutherland, M., Walt, D. R. & 6 others, West, A. B., Zhang, J., Chen-Plotkin, A., Scherzer, C. R., Vaillancourt, D. E. & Rosenthal, L. S., Jun 2017, In : Biomarkers in Medicine. 11, 6, p. 451-473 23 p.

Research output: Contribution to journalReview article

18 Scopus citations

Pattern Discovery from Directional High-Order Drug-Drug Interaction Relations

Ning, X., Schleyer, T., Shen, L. & Li, L., Sep 8 2017, Proceedings - 2017 IEEE International Conference on Healthcare Informatics, ICHI 2017. Cummins, M., Facelli, J., Meixner, G., Giraud-Carrier, C. & Nakajima, H. (eds.). Institute of Electrical and Electronics Engineers Inc., p. 154-162 9 p. 8031143. (Proceedings - 2017 IEEE International Conference on Healthcare Informatics, ICHI 2017).

Research output: Chapter in Book/Report/Conference proceedingConference contribution

3 Scopus citations

Pattern Discovery in Brain Imaging Genetics via SCCA Modeling with a Generic Non-convex Penalty

Du, L., Liu, K., Yao, X., Yan, J., Risacher, S. L., Han, J., Guo, L., Saykin, A. J., Shen, L., Weiner, M. W., Aisen, P., Petersen, R., Jack, C. R., Jagust, W., Trojanowki, J. Q., Toga, A. W., Beckett, L., Green, R. C., Morris, J., Shaw, L. M. & 293 others, Khachaturian, Z., Sorensen, G., Carrillo, M., Kuller, L., Raichle, M., Paul, S., Davies, P., Fillit, H., Hefti, F., Holtzman, D., Mesulam, M. M., Potter, W., Snyder, P., Schwartz, A., Montine, T., Thomas, R. G., Donohue, M., Walter, S., Gessert, D., Sather, T., Jiminez, G., Balasubramanian, A. B., Mason, J., Sim, I., Harvey, D., Bernstein, M., Fox, N., Thompson, P., Schuff, N., Decarli, C., Borowski, B., Gunter, J., Senjem, M., Vemuri, P., Jones, D., Kantarci, K., Ward, C., Koeppe, R. A., Foster, N., Reiman, E. M., Chen, K., Mathis, C., Landau, S., Cairns, N. J., Franklin, E., Taylor-Reinwald, L., Lee, V., Korecka, M., Figurski, M., Crawford, K., Neu, S., Foroud, T. M., Potkin, S., Faber, K., Kim, S., Nho, K., Thal, L., Buckholtz, N., Albert, M., Frank, R., Hsiao, J., Kaye, J., Quinn, J., Silbert, L., Lind, B., Carter, R., Dolen, S., Schneider, L. S., Pawluczyk, S., Beccera, M., Teodoro, L., Spann, B. M., Brewer, J., Vanderswag, H., Fleisher, A., Heidebrink, J. L., Lord, J. L., Mason, S. S., Albers, C. S., Knopman, D., Johnson, K., Doody, R. S., Villanueva-Meyer, J., Pavlik, V., Shibley, V., Chowdhury, M., Rountree, S., Dang, M., Stern, Y., Honig, L. S., Bell, K. L., Ances, B., Carroll, M., Creech, M. L., Franklin, E., Mintun, M. A., Schneider, S., Oliver, A., Marson, D., Geldmacher, D., Love, M. N., Griffith, R., Clark, D., Brockington, J., Roberson, E., Grossman, H., Mitsis, E., Shah, R. C., Detoledo-Morrell, L., Duara, R., Greig-Custo, M. T., Barker, W., Onyike, C., D'Agostino, D., Kielb, S., Sadowski, M., Sheikh, M. O., Ulysse, A., Gaikwad, M., Murali Doraiswamy, P., Petrella, J. R., Borges-Neto, S., Wong, T. Z., Coleman, E., Arnold, S. E., Karlawish, J. H., Wolk, D. A., Clark, C. M., Smith, C. D., Jicha, G., Hardy, P., Sinha, P., Oates, E., Conrad, G., Lopez, O. L., Oakley, M. A., Simpson, D. M., Porsteinsson, A. P., Goldstein, B. S., Martin, K., Makino, K. M., Ismail, M. S., Brand, C., Preda, A., Nguyen, D., Womack, K., Mathews, D., Quiceno, M., Levey, A. I., Lah, J. J., Cellar, J. S., Burns, J. M., Swerdlow, R. H., Brooks, W. M., Apostolova, L., Tingus, K., Woo, E., Silverman, D. H. S., Lu, P. H., Bartzokis, G., Graff-Radford, N. R., Parfitt, F., Poki-Walker, K., Farlow, M. R., Marie Hake, A., Matthews, B. R., Brosch, J. R., Herring, S., Van Dyck, C. H., Carson, R. E., MacAvoy, M. G., Varma, P., Chertkow, H., Bergman, H., Hosein, C., Black, S., Stefanovic, B., Caldwell, C., Robin Hsiung, G. Y., Mudge, B., Sossi, V., Feldman, H., Assaly, M., Finger, E., Pasternack, S., Rachisky, I., Rogers, J., Trost, D., Kertesz, A., Bernick, C., Munic, D., Rogalski, E., Lipowski, K., Weintraub, S., Bonakdarpour, B., Kerwin, D., Wu, C. K., Johnson, N., Sadowsky, C., Villena, T., Scott Turner, R., Johnson, K., Reynolds, B., Sperling, R. A., Johnson, K. A., Marshall, G., Yesavage, J., Taylor, J. L., Lane, B., Rosen, A., Tinklenberg, J., Sabbagh, M. N., Belden, C. M., Jacobson, S. A., Sirrel, S. A., Kowall, N., Killiany, R., Budson, A. E., Norbash, A., Lynn Johnson, P., Obisesan, T. O., Wolday, S., Allard, J., Lerner, A., Ogrocki, P., Tatsuoka, C., Fatica, P., Fletcher, E., Maillard, P., Olichney, J., Decarli, C., Carmichael, O., Kittur, S., Borrie, M., Lee, T. Y., Bartha, R., Johnson, S., Asthana, S., Carlsson, C. M., Tariot, P., Burke, A., Milliken, A. M., Trncic, N., Fleisher, A., Reeder, S., Bates, V., Capote, H., Rainka, M., Scharre, D. W., Kataki, M., Kelly, B., Zimmerman, E. A., Celmins, D., Brown, A. D., Pearlson, G. D., Blank, K., Anderson, K., Flashman, L. A., Seltzer, M., Hynes, M. L., Santulli, R. B., Sink, K. M., Gordineer, L., Williamson, J. D., Garg, P., Watkins, F., Ott, B. R., Tremont, G., Daiello, L. A., Salloway, S., Malloy, P., Correia, S., Rosen, H. J., Miller, B. L., Perry, D., Mintzer, J., Spicer, K., Bachman, D., Pomara, N., Hernando, R., Sarrael, A., Schultz, S. K., Ekstam Smith, K., Koleva, H., Nam, K. W., Shim, H., Relkin, N., Chaing, G., Lin, M., Ravdin, L., Smith, A., Ashok Raj, B. & Fargher, K., Dec 1 2017, In : Scientific reports. 7, 1, 14052.

Research output: Contribution to journalArticle

3 Scopus citations

Penetrance estimate of LRRK2 p.G2019S mutation in individuals of non-Ashkenazi Jewish ancestry

for the Michael J. Fox LRRK2 Cohort Consortium, Oct 2017, In : Movement Disorders. 32, 10, p. 1432-1438 7 p.

Research output: Contribution to journalArticle

35 Scopus citations

Polo-like kinase 1 (Plk1) overexpression enhances ionizing radiation-induced cancer formation in mice

Li, Z., Liu, J., Li, J., Kong, Y., Sandusky, G., Rao, X., Liu, Y., Wan, J. & Liu, X., Oct 20 2017, In : Journal of Biological Chemistry. 292, 42, p. 17461-17472 12 p.

Research output: Contribution to journalArticle

12 Scopus citations

Polygenic risk scores in familial Alzheimer disease

Tosto, G., Bird, T. D., Tsuang, D., Bennett, D. A., Boeve, B. F., Cruchaga, C., Faber, K., Foroud, T. M., Farlow, M., Goate, A. M., Bertlesen, S., Graff-Radford, N. R., Medrano, M., Lantigua, R., Manly, J., Ottman, R., Rosenberg, R., Schaid, D. J., Schupf, N., Stern, Y. & 2 others, Sweet, R. A. & Mayeux, R., Mar 21 2017, In : Neurology. 88, 12, p. 1180-1186 7 p.

Research output: Contribution to journalArticle

14 Scopus citations

Polygenic Scores for Major Depressive Disorder and Risk of Alcohol Dependence

Andersen, A. M., Pietrzak, R. H., Kranzler, H. R., Ma, L., Zhou, H., Liu, X., Kramer, J., Kuperman, S., Edenberg, H. J., Nurnberger, J. I., Rice, J. P., Tischfield, J. A., Goate, A., Foroud, T. M., Meyers, J. L., Porjesz, B., Dick, D. M., Hesselbrock, V., Boerwinkle, E., Southwick, S. M. & 6 others, Krystal, J. H., Weissman, M. M., Levinson, D. F., Potash, J. B., Gelernter, J. & Han, S., Nov 1 2017, In : JAMA psychiatry. 74, 11, p. 1153-1160 8 p.

Research output: Contribution to journalArticle

25 Scopus citations

Potential role of antiestrogens in treating ovarian cancer

Mitra, S. & Mitra, A. K., May 1 2017, In : Translational Cancer Research. 6, p. S614-S616

Research output: Contribution to journalEditorial

Precision medicine in pharmacometrics and systems pharmacology

Li, L., Mar 1 2017, In : CPT: Pharmacometrics and Systems Pharmacology. 6, 3, p. 151-152 2 p.

Research output: Contribution to journalEditorial

Predicting High-Order Directional Drug-Drug Interaction Relations

Ning, X., Shen, L. & Li, L., Sep 8 2017, Proceedings - 2017 IEEE International Conference on Healthcare Informatics, ICHI 2017. Cummins, M., Facelli, J., Meixner, G., Giraud-Carrier, C. & Nakajima, H. (eds.). Institute of Electrical and Electronics Engineers Inc., p. 556-561 6 p. 8031212. (Proceedings - 2017 IEEE International Conference on Healthcare Informatics, ICHI 2017).

Research output: Chapter in Book/Report/Conference proceedingConference contribution

3 Scopus citations

Predictive accuracy of serial transvaginal cervical lengths and quantitative vaginal fetal fibronectin levels for spontaneous preterm birth among nulliparous women

Sean Esplin, M., Elovitz, M. A., Iams, J. D., Parker, C. B., Wapner, R. J., Grobman, W. A., Simhan, H. N., Wing, D. A., Haas, D. M., Silver, R. M., Hoffman, M. K., Peaceman, A. M., Caritis, S. N., Parry, S., Wadhwa, P., Foroud, T., Mercer, B. M., Hunter, S. M., Saade, G. R. & Reddy, U. M., Jan 1 2017, In : Obstetrical and Gynecological Survey. 72, 7, p. 397-399 3 p.

Research output: Contribution to journalComment/debate

Predictive accuracy of serial transvaginal cervical lengths and quantitative vaginal fetal fibronectin levels for spontaneous preterm birth among nulliparous women

Esplin, M. S., Elovitz, M. A., Iams, J. D., Parker, C. B., Wapner, R. J., Grobman, W. A., Simhan, H. N., Wing, D. A., Haas, D. M., Silver, R. M., Hoffman, M. K., Peaceman, A. M., Caritis, S. N., Parry, S., Wadhwa, P., Foroud, T., Mercer, B. M., Hunter, S. M., Saade, G. R. & Reddy, U. M., Mar 14 2017, In : JAMA - Journal of the American Medical Association. 317, 10, p. 1047-1056 10 p.

Research output: Contribution to journalArticle

55 Scopus citations

Rare coding variants in PLCG2, ABI3, and TREM2 implicate microglial-mediated innate immunity in Alzheimer's disease

Sims, R., Van Der Lee, S. J., Naj, A. C., Bellenguez, C., Badarinarayan, N., Jakobsdottir, J., Kunkle, B. W., Boland, A., Raybould, R., Bis, J. C., Martin, E. R., Grenier-Boley, B., Heilmann-Heimbach, S., Chouraki, V., Kuzma, A. B., Sleegers, K., Vronskaya, M., Ruiz, A., Graham, R. R., Olaso, R. & 426 others, Hoffmann, P., Grove, M. L., Vardarajan, B. N., Hiltunen, M., Nöthen, M. M., White, C. C., Hamilton-Nelson, K. L., Epelbaum, J., Maier, W., Choi, S. H., Beecham, G. W., Dulary, C., Herms, S., Smith, A. V., Funk, C. C., Derbois, C., Forstner, A. J., Ahmad, S., Li, H., Bacq, D., Harold, D., Satizabal, C. L., Valladares, O., Squassina, A., Thomas, R., Brody, J. A., Qu, L., Sánchez-Juan, P., Morgan, T., Wolters, F. J., Zhao, Y., Garcia, F. S., Denning, N., Fornage, M., Malamon, J., Naranjo, M. C. D., Majounie, E., Mosley, T. H., Dombroski, B., Wallon, D., Lupton, M. 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A., Powell, J., Golde, T. E., Graff, C., De Jager, P. L., Morgan, K., Ertekin-Taner, N., Combarros, O., Psaty, B. M., Passmore, P., Younkin, S. G., Berr, C., Gudnason, V., Rujescu, D., Dickson, D. W., Dartigues, J. F., Destefano, A. L., Ortega-Cubero, S., Hakonarson, H., Campion, D., Boada, M., Kauwe, J. K., Farrer, L. A., Van Broeckhoven, C., Ikram, M. A., Jones, L., Haines, J. L., Tzourio, C., Launer, L. J., Escott-Price, V., Mayeux, R., Deleuze, J. F., Amin, N., Goate, A. M., Pericak-Vance, M. A., Holmans, P. A., Van Duijn, C. M., Ramirez, A., Wang, L. S., Lambert, J. C., Seshadri, S., Williams, J. & Schellenberg, G. D., Sep 1 2017, In : Nature genetics. 49, 9, p. 1373-1384 12 p.

Research output: Contribution to journalArticle

232 Scopus citations

RareVar: A Framework for Detecting Low-Frequency Single-Nucleotide Variants

Hao, Y., Xuei, X., Li, L., Nakshatri, H., Edenberg, H. J. & Liu, Y., Jul 1 2017, In : Journal of Computational Biology. 24, 7, p. 637-646 10 p.

Research output: Contribution to journalArticle

3 Scopus citations

Reduction in Migratory Phenotype in a Metastasized Breast Cancer Cell Line via Downregulation of S100A4 and GRM3

Chen, A., Wang, L., Li, B. Y., Sherman, J., Ryu, J. E., Hamamura, K., Liu, Y., Nakshatri, H. & Yokota, H., Dec 1 2017, In : Scientific reports. 7, 1, 3459.

Research output: Contribution to journalArticle

10 Scopus citations

regSNPs-splicing: a tool for prioritizing synonymous single-nucleotide substitution

Zhang, X., Li, M., Lin, H., Rao, X., Feng, W., Yang, Y., Mort, M., Cooper, D. N., Wang, Y., Wang, Y., Wells, C., Zhou, Y. & Liu, Y., Sep 1 2017, In : Human genetics. 136, 9, p. 1279-1289 11 p.

Research output: Contribution to journalArticle

4 Scopus citations