Medical & Molecular Genetics

Publications

2016

Reduction of Murine Colon Tumorigenesis Driven by Enterotoxigenic Bacteroides fragilis Using Cefoxitin Treatment

Destefano Shields, C. E., Van Meerbeke, S. W., Housseau, F., Wang, H., Huso, D. L., Casero, R. A., O'Hagan, H. M. & Sears, C. L., Jul 1 2016, In : Journal of Infectious Diseases. 214, 1, p. 122-129 8 p.

Research output: Contribution to journalArticle

30 Scopus citations

Rifampin enhances cytochrome P450 (CYP) 2B6-mediated efavirenz 8-hydroxylation in healthy volunteers

Cho, D. Y., Shen, J. H. Q., Lemler, S. M., Skaar, T. C., Li, L., Blievernicht, J., Zanger, U. M., Kim, K. B., Shin, J. G., Flockhart, D. A. & Desta, Z., Apr 2016, In : Drug Metabolism and Pharmacokinetics. 31, 2, p. 107-116 10 p.

Research output: Contribution to journalArticle

6 Scopus citations

Rifampin regulation of drug transporters gene expression and the association of microRNAs in human hepatocytes

Benson, E., Eadon, M., Desta, Z., Liu, Y., Lin, H., Burgess, K. S., Segar, M. W., Gaedigk, A. & Skaar, T., Apr 26 2016, In : Frontiers in Pharmacology. 7, APR, 111.

Research output: Contribution to journalArticle

20 Scopus citations

Robust differentiation of mRNA-reprogrammed human induced pluripotent stem cells toward a retinal lineage

Sridhar, A., Ohlemacher, S. K., Langer, K. B. & Meyer, J. S., Jan 1 2016, In : Stem Cells Translational Medicine. 5, 4, p. 417-426 10 p.

Research output: Contribution to journalArticle

Open Access
20 Scopus citations

Selective suppression of the α isoform of p38 MAPK rescues late-stage tau pathology

Maphis, N., Jiang, S., Xu, G., Kokiko-Cochran, O. N., Roy, S. M., Van Eldik, L. J., Watterson, D. M., Lamb, B. T. & Bhaskar, K., Dec 15 2016, In : Alzheimer's Research and Therapy. 8, 1, p. 1-15 15 p.

Research output: Contribution to journalArticle

30 Scopus citations

Shared genetic contribution to ischemic stroke and Alzheimer's disease

Traylor, M., Adib-Samii, P., Harold, D., Dichgans, M., Williams, J., Lewis, C. M., Markus, H. S., Fornage, M., Holliday, E. G., Sharma, P., Bis, J. C., Psaty, B. M., Seshadri, S., Nalls, M. A., Devan, W. J., Boncoraglio, G., Malik, R., Mitchell, B. D., Kittner, S. J., Ikram, M. A. & 188 others, Clarke, R., Rosand, J., Meschia, J. F., Sudlow, C., Rothwell, P. M., Levi, C., Bevan, S., Kilarski, L. L., Walters, M., Thijs, V., Slowik, A., Lindgren, A., De Bakker, P. I. W., Lambert, J. C., Ibrahim-Verbaas, C. A., Naj, A. C., Sims, R., Bellenguez, C., Jun, G., Destefano, A. L., Beecham, G. W., Grenier-Boley, B., Russo, G., Thornton-Wells, T. A., Jones, N., Smith, A. V., Chouraki, V., Thomas, C., Zelenika, D., Vardarajan, B. N., Kamatani, Y., Lin, C. F., Gerrish, A., Schmidt, H., Kunkle, B., Dunstan, M. L., Ruiz, A., Bihoreau, M. T., Choi, S. H., Reitz, C., Pasquier, F., Hollingworth, P., Ramirez, A., Hanon, O., Fitzpatrick, A. L., Buxbaum, J. D., Campion, D., Crane, P. K., Baldwin, C., Becker, T., Gudnason, V., Cruchaga, C., Craig, D., Amin, N., Berr, C., Lopez, O. L., De Jager, P. L., Deramecourt, V., Johnston, J. A., Evans, D., Lovestone, S., Letenneur, L., Morón, F. J., Rubinsztein, D. C., Eiriksdottir, G., Sleegers, K., Goate, A. M., Fiçvet, N., Huentelman, M. J., Gill, M., Brown, K., Kamboh, M. I., Keller, L., Barberger-Gateau, P., McGuinness, B., Larson, E. B., Green, R., Myers, A. J., Dufouil, C., Todd, S., Wallon, D., Love, S., Rogaeva, E., Gallacher, J., St George-Hyslop, P., Clarimon, J., Lleo, A., Bayer, A., Tsuang, D. W., Yu, L., Tsolaki, M., Bossù, P., Spalletta, G., Proitsi, P., Collinge, J., Sorbi, S., Sanchez-Garcia, F., Fox, N. C., Hardy, J., Deniz Naranjo, M. C., Bosco, P., Brayne, C., Galimberti, D., Mancuso, M., Matthews, F., Moebus, S., Mecocci, P., Del Zompo, M., Maier, W., Hampel, H., Pilotto, A., Bullido, M., Panza, F., Caffarra, P., Nacmias, B., Gilbert, J. R., Mayhaus, M., Lannfelt, L., Hakonarson, H., Pichler, S., Carrasquillo, M. M., Ingelsson, M., Beekly, D., Alvarez, V., Zou, F., Valladares, O., Younkin, S. G., Coto, E., Hamilton-Nelson, K. L., Gu, W., Razquin, C., Pastor, P., Mateo, I., Owen, M. J., Faber, K. M., Jonsson, P. V., Combarros, O., O'Donovan, M. C., Cantwell, L. B., Soininen, H., Blacker, D., Mead, S., Mosley, T. H., Bennett, D. A., Harris, T. B., Fratiglioni, L., Holmes, C., De Bruijn, R. F. A. G., Passmore, P., Montine, T. J., Bettens, K., Rotter, J. I., Brice, A., Morgan, K., Foroud, T. M., Kukull, W. A., Hannequin, D., Powell, J. F., Nalls, M. A., Ritchie, K., Lunetta, K. L., Kauwe, J. S. K., Boerwinkle, E., Riemenschneider, M., Boada, M., Hiltunen, M., Martin, E. R., Schmidt, R., Rujescu, D., Wang, L. S., Dartigues, J. F., Mayeux, R., Tzourio, C., Hofman, A., Nöthen, M. M., Graff, C., Jones, L., Haines, J. L., Holmans, P. A., Lathrop, M., Pericak-Vance, M. A., Launer, L. J., Farrer, L. A., Van Duijn, C. M., Van Broeckhoven, C., Moskvina, V., Schellenberg, G. D. & Amouyel, P., May 1 2016, In : Annals of neurology. 79, 5, p. 739-747 9 p.

Research output: Contribution to journalArticle

26 Scopus citations

Shared genetic risk factors of intracranial, abdominal, and thoracic aneurysms

Aneurysm Consortium, Vascular Research Consortium of New Zealand, Jul 2016, In : Journal of the American Heart Association. 5, 7, e002603.

Research output: Contribution to journalArticle

17 Scopus citations

Statistical modeling for sensitive detection of low-frequency single nucleotide variants

Hao, Y., Zhang, P., Xuei, X., Nakshatri, H., Edenberg, H. J., Li, L. & Liu, Y., Aug 22 2016, In : BMC genomics. 17, 514.

Research output: Contribution to journalArticle

3 Scopus citations

Stepwise Differentiation of Retinal Ganglion Cells from Human Pluripotent Stem Cells Enables Analysis of Glaucomatous Neurodegeneration

Ohlemacher, S. K., Sridhar, A., Xiao, Y., Hochstetler, A. E., Sarfarazi, M., Cummins, T. R. & Meyer, J. S., Jun 1 2016, In : STEM CELLS. 34, 6, p. 1553-1562 10 p.

Research output: Contribution to journalArticle

49 Scopus citations

Steroid Pathway Genes and Neonatal Respiratory Distress after Betamethasone Use in Anticipated Preterm Birth

Haas, D. M., Lai, D., Sharma, S., Then, J., Kho, A., Flockhart, D. A., Tantisira, K. & Foroud, T., Jan 1 2016, In : Reproductive Sciences. 23, 5, p. 680-686 7 p.

Research output: Contribution to journalArticle

6 Scopus citations

Systematic quality control analysis of LINCS data

Cheng, L. & Li, L., Nov 1 2016, In : CPT: Pharmacometrics and Systems Pharmacology. 5, 11, p. 588-598 11 p.

Research output: Contribution to journalArticle

8 Scopus citations

The impact of oculomotor functioning on neuropsychological performance in Huntington disease

Carvalho, J. O., Long, J. D., Westervelt, H. J., Smith, M. M., Bruce, J. M., Kim, J. I., Mills, J. A., Paulsen, J. S., De Soriano, I., Shadrick, C., Miller, A., Chiu, E., Preston, J., Goh, A., Antonopoulos, S., Loi, S., Chua, P., Komiti, A., Raymond, L., Decolongon, J. & 107 others, Fan, M., Coleman, A., Ross, C. A., Varvaris, M., Ong, M., Yoritomo, N., Mallonee, W. M., Suter, G., Samii, A., Freney, E. P., Macaraeg, A., Jones, R., Wood-Siverio, C., Factor, S. A., Barker, R. A., Mason, S., Guzman, N. V., McCusker, E., Griffith, J., Loy, C., McMillan, J., Gunn, D., Orth, M., Süßmuth, S., Barth, K., Trautmann, S., Schwenk, D., Eschenbach, C., Quaid, K., Wesson, M., Wojcieszek, J., Guttman, M., Sheinberg, A., Law, A., Karmalkar, I., Perlman, S., Clemente, B., Geschwind, M. D., Sha, S., Winer, J., Satris, G., Warner, T., Burrows, M., Rosser, A., Price, K., Hunt, S., Marshall, F., Chesire, A., Wodarski, M., Hickey, C., Panegyres, P., Lee, J., Tedesco, M., Maxwell, B., Perlmutter, J., Barton, S., Smith, S., Miedzybrodzka, Z., Rae, D., Vaughan, V., D'Alessandro, M., Craufurd, D., Bek, J., Howard, E., Mazzoni, P., Marder, K., Wasserman, P., Kumar, R., Erickson, D., Reeves, C., Nickels, B., Wheelock, V., Kjer, L., Martin, A., Farias, S., Martin, W., Suchowersky, O., King, P., Wieler, M., Sran, S., Ahmed, A., Rao, S., Reece, C., Bura, A., Mourany, L., Danzer, P., Montross, K., Harrington, D., Westervalt, H., Aylward, E., Moser, D. J., Williams, J., Downing, N., Magnotta, V. A., Johnson, H. J., Brashers-Krug, T., Vaidya, J., O'Leary, D., Young Kim, E., Lourens, S., Zhang, Y., Lu, W., Erwin, C., Nance, M., Bockholt, H. J., Evans, J. & Zschiegner, R., Feb 7 2016, In : Journal of Clinical and Experimental Neuropsychology. 38, 2, p. 217-226 10 p.

Research output: Contribution to journalArticle

3 Scopus citations

The role of cardiovascular risk factors and stroke in familial Alzheimer disease

Tosto, G., Bird, T. D., Bennett, D. A., Boeve, B. F., Brickman, A. M., Cruchaga, C., Faber, K., Foroud, T. M., Farlow, M., Goate, A. M., Graff-Radford, N. R., Lantigua, R., Manly, J., Ottman, R., Rosenberg, R., Schaid, D. J., Schupf, N., Stern, Y., Sweet, R. A. & Mayeux, R., Oct 1 2016, In : JAMA Neurology. 73, 10, p. 1231-1237 7 p.

Research output: Contribution to journalArticle

24 Scopus citations

The social symbiome framework: Linking genes-to-global cultures in public health using network science

Pescosolido, B. A., Olafsdottir, S., Sporns, O., Perry, B. L., Meslin, E. M., Grubesic, T. H., Martin, J. K., Koehly, L. M., Pridemore, W., Vespignani, A., Foroud, T. & Shekhar, A., Nov 25 2016, Handbook of Applied System Science. Taylor and Francis Inc., p. 25-48 24 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

4 Scopus citations

Tissue-specific Co-expression of Long Non-coding and Coding RNAs Associated with Breast Cancer

Wu, W., Wagner, E. K., Hao, Y., Rao, X., Dai, H., Han, J., Chen, J., Storniolo, A. M. V., Liu, Y. & He, C., Sep 6 2016, In : Scientific reports. 6, 32731.

Research output: Contribution to journalArticle

15 Scopus citations

Transcriptome analysis reveals manifold mechanisms of cyst development in ADPKD

De Almeida, R. M. C., Clendenon, S. G., Richards, W. G., Boedigheimer, M., Damore, M., Rossetti, S., Harris, P. C., Herbert, B. S., Xu, W. M., Wandinger-Ness, A., Ward, H. H., Glazier, J. A. & Bacallao, R. L., Nov 21 2016, In : Human genomics. 10, 1, p. 1-24 24 p.

Research output: Contribution to journalArticle

9 Scopus citations

Transmembrane protein 88 (TMEM88) promoter hypomethylation is associated with platinum resistance in ovarian cancer

de Leon, M., Cardenas, H., Vieth, E., Emerson, R., Segar, M., Liu, Y., Nephew, K. & Matei, D., Sep 1 2016, In : Gynecologic oncology. 142, 3, p. 539-547 9 p.

Research output: Contribution to journalArticle

16 Scopus citations

Weaver Syndrome-Associated EZH2 Protein Variants Show Impaired Histone Methyltransferase Function In Vitro

Cohen, A. S. A., Yap, D. B., Lewis, M. E. S., Chijiwa, C., Ramos-Arroyo, M. A., Tkachenko, N., Milano, V., Fradin, M., Mckinnon, M. L., Townsend, K. N., Xu, J., Van Allen, M. I., Ross, C. J. D., Dobyns, W. B., Weaver, D. D. & Gibson, W. T., Mar 1 2016, In : Human Mutation. 37, 3, p. 301-307 7 p.

Research output: Contribution to journalArticle

23 Scopus citations

Whole-exome sequencing in familial Parkinson disease

Farlow, J. L., Robak, L. A., Hetrick, K., Bowling, K., Boerwinkle, E., Coban-Akdemir, Z. H., Gambin, T., Gibbs, R. A., Gu, S., Jain, P., Jankovic, J., Jhangiani, S., Kaw, K., Lai, D., Lin, H., Ling, H., Liu, Y., Lupski, J. R., Muzny, D., Porter, P. & 6 others, Pugh, E., White, J., Doheny, K., Myers, R. M., Shulman, J. M. & Foroud, T., Jan 2016, In : JAMA Neurology. 73, 1, p. 68-75 8 p.

Research output: Contribution to journalArticle

32 Scopus citations

Widespread telomere instability in prostatic lesions

Tu, L., Huda, N., Grimes, B. R., Slee, R. B., Bates, A. M., Cheng, L. & Gilley, D., May 1 2016, In : Molecular Carcinogenesis. 55, 5, p. 842-852 11 p.

Research output: Contribution to journalArticle

5 Scopus citations
2015

Aberrant reduction of telomere repetitive sequences in plasma cell-free DNA for early breast cancer detection

Wu, X. & Tanaka, H., Jan 1 2015, In : Oncotarget. 6, 30, p. 29795-29807 13 p.

Research output: Contribution to journalArticle

7 Scopus citations
13 Scopus citations

Affected twins in the familial intracranial aneurysm study

Mackey, J., Brown, R. D., Sauerbeck, L., Hornung, R., Moomaw, C. J., Koller, D. L., Foroud, T., Deka, R., Woo, D., Kleindorfer, D., Flaherty, M. L., Meissner, I., Anderson, C., Rouleau, G., Connolly, E. S., Huston, J. & Broderick, J. P., Mar 6 2015, In : Cerebrovascular Diseases. 39, 2, p. 82-86 5 p.

Research output: Contribution to journalArticle

9 Scopus citations

Age-related changes in MicroRNA expression and pharmacogenes in human liver

Burgess, K. S., Philips, S., Benson, E. A., Desta, Z., Gaedigk, A., Gaedigk, R., Segar, M. W., Liu, Y. & Skaar, T. C., Aug 1 2015, In : Clinical Pharmacology and Therapeutics. 98, 2, p. 205-215 11 p.

Research output: Contribution to journalArticle

19 Scopus citations

AluY-mediated germline deletion, duplication and somatic stem cell reversion in UBE2T defines a new subtype of Fanconi anemia

Virts, E. L., Jankowska, A., Mackay, C., Glaas, M. F., Wiek, C., Kelich, S. L., Lottmann, N., Kennedy, F. M., Marchal, C., Lehnert, E., Scharf, R. E., Dufour, C., Lanciotti, M., Farruggia, P., Santoro, A., Savasan, S., Scheckenbach, K., Schipper, J., Wagenmann, M., Lewis, T. & 12 others, Leffak, M., Farlow, J. L., Foroud, T. M., Honisch, E., Niederacher, D., Chakraborty, S. C., Vance, G. H., Pruss, D., Timms, K. M., Lanchbury, J. S., Alpi, A. F. & Hanenberg, H., Apr 9 2015, In : Human molecular genetics. 24, 18, p. 5093-5108 16 p.

Research output: Contribution to journalArticle

42 Scopus citations

A Mixture Dose-Response Model for Identifying High-Dimensional Drug Interaction Effects on Myopathy Using Electronic Medical Record Databases

Zhang, P., Du, L., Wang, L., Liu, M., Cheng, L., Chiang, C. W., Wu, H. Y., Quinney, S. K., Shen, L. & Li, L., Aug 1 2015, In : CPT: Pharmacometrics and Systems Pharmacology. 4, 8, p. 474-480 7 p.

Research output: Contribution to journalArticle

9 Scopus citations

A multiancestral genome-wide exome array study of Alzheimer Disease, frontotemporal dementia, and progressive supranuclear palsy

Chen, J. A., Wang, Q., Davis-Turak, J., Li, Y., Karydas, A. M., Hsu, S. C., Sears, R. L., Chatzopoulou, D., Huang, A. Y., Wojta, K. J., Klein, E., Lee, J., Beekly, D. L., Boxer, A., Faber, K. M., Haase, C. M., Miller, J., Poon, W. W., Rosen, A., Rosen, H. & 15 others, Sapozhnikova, A., Shapira, J., Varpetian, A., Foroud, T. M., Levenson, R. W., Levey, A. I., Kukull, W. A., Mendez, M. F., Ringman, J., Chui, H., Cotman, C., DeCarli, C., Miller, B. L., Geschwind, D. H. & Coppola, G., Apr 1 2015, In : JAMA Neurology. 72, 4, p. 414-422 9 p.

Research output: Contribution to journalArticle

20 Scopus citations

An atypical case of canavan disease with stroke-like presentation

Delaney, K. E., Kralik, S. F., Hainline, B. E. & Golomb, M. R., Feb 1 2015, In : Pediatric Neurology. 52, 2, p. 218-221 4 p.

Research output: Contribution to journalArticle

5 Scopus citations

A new drug combinatory effect prediction algorithm on the cancer cell based on gene expression and dose-response curve

Goswami, C. P., Cheng, L., Alexander, P. S., Singal, A. & Li, L., Feb 1 2015, In : CPT: Pharmacometrics and Systems Pharmacology. 4, 2, p. 80-90 11 p.

Research output: Contribution to journalArticle

11 Scopus citations

An infant with large fontanelles, aplasia cutis congenita, tessier facial cleft, polydactyly inversus, and toe syndactyly: A previously undescribed syndrome?

Jackson, J., Delk, P., Farrow, E., Griffith, C., Lah, M. & Weaver, D. D., Apr 1 2015, In : American Journal of Medical Genetics, Part A. 167, 4, p. 683-687 5 p.

Research output: Contribution to journalArticle

APOE effect on Alzheimer's disease biomarkers in older adults with significant memory concern

Risacher, S. L., Kim, S., Nho, K., Foroud, T., Shen, L., Petersen, R. C., Jack, C. R., Beckett, L. A., Aisen, P. S., Koeppe, R. A., Jagust, W. J., Shaw, L. M., Trojanowski, J. Q., Weiner, M. W., Saykin, A. J. & Alzheimer's Disease Neuroimaging Initiative (ADNI), D. N. I. ADNI., Dec 1 2015, In : Alzheimer's and Dementia. 11, 12, p. 1417-1429 13 p.

Research output: Contribution to journalArticle

76 Scopus citations

A randomized noninferiority trial of condensed protocols for genetic risk disclosure of Alzheimer's disease

Green, R. C., Christensen, K. D., Cupples, L. A., Relkin, N. R., Whitehouse, P. J., Royal, C. D. M., Obisesan, T. O., Cook-Deegan, R., Linnenbringer, E., Butson, M. B., Fasaye, G. A., Levinson, E., Roberts, J. S., Bhatt, D., Biesecker, B., Blacker, D., Chen, C., Cox, E., Davis, J. G., Farrer, L. & 22 others, Griffith, P., Harkins, K., Hiraki, S., Johnson, M., Johnson, S., Juengst, E., Karlawish, J., Le, L., McCarty Wood, E., Obisesan, T., Post, S., Quaid, K., Ravdin, L., Roter, D., Stern, R., Sadovnick, A., Sami, S., Sankar, P., Topol, E., Uhlmann, W., Waterston, L. & Wright, L., Oct 2015, In : Alzheimer's and Dementia. 11, 10, p. 1222-1230 9 p.

Research output: Contribution to journalArticle

19 Scopus citations

Association of long runs of homozygosity with Alzheimer disease among African American individuals

Ghani, M., Reitz, C., Cheng, R., Vardarajan, B. N., Jun, G., Sato, C., Naj, A., Rajbhandary, R., Wang, L. S., Valladares, O., Lin, C. F., Larson, E. B., Graff-Radford, N. R., Evans, D., De Jager, P. L., Crane, P. K., Buxbaum, J. D., Murrell, J. R., Raj, T., Ertekin-Taner, N. & 153 others, Logue, M., Baldwin, C. T., Green, R. C., Barnes, L. L., Cantwell, L. B., Fallin, M. D., Go, R. C. P., Griffith, P. A., Obisesan, T. O., Manly, J. J., Lunetta, K. L., Kamboh, M. I., Lopez, O. L., Bennett, D. A., Hendrie, H., Hall, K. S., Goate, A. M., Byrd, G. S., Kukull, W. A., Foroud, T. M., Haines, J. L., Farrer, L. A., Pericak-Vance, M. A., Lee, J. H., Schellenberg, G. D., St. George-Hyslop, P., Mayeux, R., Rogaeva, E., Albert, M. S., Albin, R. L., Apostolova, L. G., Arnold, S. E., Barber, R., Barmada, M. M., Beach, T. G., Beecham, G. W., Beekly, D., Bigio, E. H., Bird, T. D., Blacker, D., Boeve, B. F., Bowen, J. D., Boxer, A., Burke, J. R., Cai, G., Cairns, N. J., Cao, C., Carlson, C. S., Carney, R. M., Carroll, S. L., Chui, H. C., Clark, D. G., Cribbs, D. H., Crocco, E. A., Cruchaga, C., DeCarli, C., DeKosky, S. T., Demirci, F. Y., Dick, M., Faber, K. M., Fallon, K. B., Ferris, S., Frosch, M. P., Galasko, D. R., Ganguli, M., Gearing, M., Geschwind, D. H., Ghetti, B., Gilbert, J. R., Gilman, S., Glass, J. D., Growdon, J. H., Hakonarson, H., Hamilton, R. L., Hamilton-Nelson, K. L., Haroutunian, V., Harrell, L. E., Honig, L. S., Hulette, C. M., Hyman, B. T., Jarvik, G. P., Jicha, G. A., Jin, L. W., Karydas, A., Kauwe, J. S. K., Kaye, J. A., Kim, R., Koo, E. H., Kowall, N. W., Kramer, J. H., Kramer, P., LaFerla, F. M., Lah, J. J., Lang-Walker, R., Leverenz, J. B., Levey, A. I., Li, G., Lieberman, A. P., Lyketsos, C. G., Mack, W. J., Marson, D. C., Martiniuk, F., Mash, D. C., Masliah, E., McCormick, W. C., McCurry, S. M., McDavid, A. N., McKee, A. C., Mesulam, M., Miller, B. L., Miller, C. A., Miller, J. W., Montine, T. J., Morris, J. C., Olichney, J. M., Parisi, J. E., Peskind, E., Petersen, R. C., Pierce, A., Poon, W. W., Potter, H., Quinn, J. F., Raj, A., Raskind, M., Reiman, E. M., Reisberg, B., Ringman, J. M., Roberson, E. D., Sano, M., Saykin, A. J., Schneider, J. A., Schneider, L. S., Seeley, W. W., Smith, A. G., Sonnen, J. A., Spina, S., Stern, R. A., Tanzi, R. E., Trojanowski, J. Q., Troncoso, J. C., Tsuang, D. W., Van Deerlin, V. M., Van Eldik, L. J., Vinters, H. V., Vonsattel, J. P., Weintraub, S., Welsh-Bohmer, K. A., Williamson, J., Woltjer, R. L., Wright, C. B., Younkin, S. G., Yu, C. E. & Yu, L., Nov 2015, In : JAMA Neurology. 72, 11, p. 1313-1323 11 p.

Research output: Contribution to journalArticle

Open Access
18 Scopus citations

Associations between genetic variants and the effect of letrozole and exemestane on bone mass and bone turnover

Oesterreich, S., Henry, N. L., Kidwell, K. M., Van Poznak, C. H., Skaar, T. C., Dantzer, J., Li, L., Hangartner, T. N., Peacock, M., Nguyen, A. T., Rae, J. M., Desta, Z., Philips, S., Storniolo, A. M., Stearns, V., Hayes, D. F. & Flockhart, D. A., Nov 1 2015, In : Breast Cancer Research and Treatment. 154, 2, p. 263-273 11 p.

Research output: Contribution to journalArticle

15 Scopus citations

A translational bioinformatic approach in identifying and validating an interaction between Vitamin A and CYP19A1

Philips, S., Zhou, J., Li, Z., Skaar, T. C. & Li, L., Jun 11 2015, In : BMC genomics. 16, 7, S17.

Research output: Contribution to journalArticle

2 Scopus citations

Autonomous and nonautonomous regulation of Wnt-mediated neuronal polarity by the C. elegans Ror kinase CAM-1

Chien, S. C. J., Gurling, M., Kim, C., Craft, T., Forrester, W. & Garriga, G., Aug 1 2015, In : Developmental Biology. 404, 1, p. 55-65 11 p.

Research output: Contribution to journalArticle

9 Scopus citations

Bioinformatics methods and biological interpretation for next-generation sequencing data

Wang, G., Liu, Y., Zhu, D., Klau, G. W. & Feng, W., Jan 1 2015, In : BioMed research international. 2015, 690873.

Research output: Contribution to journalEditorial

1 Scopus citations

Bone structure and function

Burr, D. B., Bellido, T. & White, K. E., Jan 1 2015, Rheumatology: Sixth Edition. Elsevier Inc., Vol. 1-2. p. 42-55 14 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

1 Scopus citations

Brief report: Genetics of alcoholic Cirrhosis-GenomALC multinational study

the GenomALC Consortium, May 1 2015, In : Alcoholism: Clinical and Experimental Research. 39, 5, p. 836-842 7 p.

Research output: Contribution to journalArticle

15 Scopus citations
27 Scopus citations

Characteristics of Bipolar I patients grouped by externalizing disorders

Swaminathan, S., Koller, D. L., Foroud, T., Edenberg, H. J., Xuei, X., Niculescu, A. B. & Nurnberger, J. I., Jul 1 2015, In : Journal of Affective Disorders. 178, p. 206-214 9 p., 7324.

Research output: Contribution to journalArticle

5 Scopus citations

Characterization of hepatic enzyme activity in older adults with dementia: Potential impact on personalizing pharmacotherapy

Campbell, N. L., Skaar, T. C., Perkins, A. J., Gao, S., Li, L., Khan, B. A. & Boustani, M. A., Jan 13 2015, In : Clinical interventions in aging. 10, p. 269-275 7 p.

Research output: Contribution to journalArticle

7 Scopus citations

Chitosan/interfering RNA nanoparticle mediated gene silencing in disease vector mosquito larvae

Zhang, X., Mysore, K., Flannery, E., Michel, K., Severson, D. W., Zhu, K. Y. & Duman-Scheel, M., Mar 25 2015, In : Journal of Visualized Experiments. 2015, 97, e52523.

Research output: Contribution to journalArticle

36 Scopus citations

Chromosome 1p36.22p36.21 duplications/triplication causes Setleis syndrome (focal facial dermal dysplasia type III)

Weaver, D. D., Norby, A. R., Rosenfeld, J. A., Proud, V. K., Spangler, B. E., Ming, J. E., Chisholm, E., Zackai, E. H., Lee, B. H., Edelmann, L. & Desnick, R. J., May 1 2015, In : American Journal of Medical Genetics, Part A. 167, 5, p. 1061-1070 10 p.

Research output: Contribution to journalArticle

7 Scopus citations

Clinical use of amyloid-positron emission tomography neuroimaging: Practical and bioethical considerations

Witte, M. M., Foster, N. L., Fleisher, A. S., Williams, M. M., Quaid, K., Wasserman, M., Hunt, G., Roberts, J. S., Rabinovici, G. D., Levenson, J. L., Hake, A. M., Hunter, C. A., Van Campen, L. E., Pontecorvo, M. J., Hochstetler, H. M., Tabas, L. B. & Trzepacz, P. T., Sep 1 2015, In : Alzheimer's and Dementia: Diagnosis, Assessment and Disease Monitoring. 1, 3, p. 358-367 10 p.

Research output: Contribution to journalArticle

25 Scopus citations

Common genetic variants influence human subcortical brain structures

Hibar, D. P., Stein, J. L., Renteria, M. E., Arias-Vasquez, A., Desrivières, S., Jahanshad, N., Toro, R., Wittfeld, K., Abramovic, L., Andersson, M., Aribisala, B. S., Armstrong, N. J., Bernard, M., Bohlken, M. M., Boks, M. P., Bralten, J., Brown, A. A., Mallar Chakravarty, M., Chen, Q., Ching, C. R. K. & 267 others, Cuellar-Partida, G., Den Braber, A., Giddaluru, S., Goldman, A. L., Grimm, O., Guadalupe, T., Hass, J., Woldehawariat, G., Holmes, A. J., Hoogman, M., Janowitz, D., Jia, T., Kim, S., Klein, M., Kraemer, B., Lee, P. H., Olde Loohuis, L. M., Luciano, M., MacAre, C., Mather, K. A., Mattheisen, M., Milaneschi, Y., Nho, K., Papmeyer, M., Ramasamy, A., Risacher, S. L., Roiz-Santiañez, R., Rose, E. J., Salami, A., Sämann, P. G., Schmaal, L., Schork, A. J., Shin, J., Strike, L. T., Teumer, A., Van Donkelaar, M. M. J., Van Eijk, K. R., Walters, R. K., Westlye, L. T., Whelan, C. D., Winkler, A. M., Zwiers, M. P., Alhusaini, S., Athanasiu, L., Ehrlich, S., Hakobjan, M. M. H., Hartberg, C. B., Haukvik, U. K., Heister, A. J. G. A. M., Hoehn, D., Kasperaviciute, D., Liewald, D. C. M., Lopez, L. M., Makkinje, R. R. R., Matarin, M., Naber, M. A. M., Reese McKay, D., Needham, M., Nugent, A. C., Pütz, B., Royle, N. A., Shen, L., Sprooten, E., Trabzuni, D., Van Der Marel, S. S. L., Van Hulzen, K. J. E., Walton, E., Wolf, C., Almasy, L., Ames, D., Arepalli, S., Assareh, A. A., Bastin, M. E., Brodaty, H., Bulayeva, K. B., Carless, M. A., Cichon, S., Corvin, A., Curran, J. E., Czisch, M., De Zubicaray, G. I., Dillman, A., Duggirala, R., Dyer, T. D., Erk, S., Fedko, I. O., Ferrucci, L., Foroud, T. M., Fox, P. T., Fukunaga, M., Raphael Gibbs, J., Göring, H. H. H., Green, R. C., Guelfi, S., Hansell, N. K., Hartman, C. A., Hegenscheid, K., Heinz, A., Hernandez, D. G., Heslenfeld, D. J., Hoekstra, P. J., Holsboer, F., Homuth, G., Hottenga, J. J., Ikeda, M., Jack, C. R., Jenkinson, M., Johnson, R., Kanai, R., Keil, M., Kent, J. W., Kochunov, P., Kwok, J. B., Lawrie, S. M., Liu, X., Longo, D. L., McMahon, K. L., Meisenzahl, E., Melle, I., Mohnke, S., Montgomery, G. W., Mostert, J. C., Mühleisen, T. W., Nalls, M. A., Nichols, T. E., Nilsson, L. G., Nöthen, M. M., Ohi, K., Olvera, R. L., Perez-Iglesias, R., Bruce Pike, G., Potkin, S. G., Reinvang, I., Reppermund, S., Rietschel, M., Romanczuk-Seiferth, N., Rosen, G. D., Rujescu, D., Schnell, K., Schofield, P. R., Smith, C., Steen, V. M., Sussmann, J. E., Thalamuthu, A., Toga, A. W., Traynor, B. J., Troncoso, J., Turner, J. A., Valdés Hernández, M. C., Van 'T Ent, D., Van Der Brug, M., Van Der Wee, N. J. A., Van Tol, M. J., Veltman, D. J., Wassink, T. H., Westman, E., Zielke, R. H., Zonderman, A. B., Ashbrook, D. G., Hager, R., Lu, L., McMahon, F. J., Morris, D. W., Williams, R. W., Brunner, H. G., Buckner, R. L., Buitelaar, J. K., Cahn, W., Calhoun, V. D., Cavalleri, G. L., Crespo-Facorro, B., Dale, A. M., Davies, G. E., Delanty, N., Depondt, C., Djurovic, S., Drevets, W. C., Espeseth, T., Gollub, R. L., Ho, B. C., Hoffmann, W., Hosten, N., Kahn, R. S., Le Hellard, S., Meyer-Lindenberg, A., Müller-Myhsok, B., Nauck, M., Nyberg, L., Pandolfo, M., Penninx, B. W. J. H., Roffman, J. L., Sisodiya, S. M., Smoller, J. W., Van Bokhoven, H., Van Haren, N. E. M., Völzke, H., Walter, H., Weiner, M. W., Wen, W., White, T., Agartz, I., Andreassen, O. A., Blangero, J., Boomsma, D. I., Brouwer, R. M., Cannon, D. M., Cookson, M. R., De Geus, E. J. C., Deary, I. J., Donohoe, G., Fernández, G., Fisher, S. E., Francks, C., Glahn, D. C., Grabe, H. J., Gruber, O., Hardy, J., Hashimoto, R., Hulshoff Pol, H. E., Jönsson, E. G., Kloszewska, I., Lovestone, S., Mattay, V. S., Mecocci, P., McDonald, C., McIntosh, A. M., Ophoff, R. A., Paus, T., Pausova, Z., Ryten, M., Sachdev, P. S., Saykin, A. J., Simmons, A., Singleton, A., Soininen, H., Wardlaw, J. M., Weale, M. E., Weinberger, D. R., Adams, H. H. H., Launer, L. J., Seiler, S., Schmidt, R., Chauhan, G., Satizabal, C. L., Becker, J. T., Yanek, L., Van Der Lee, S. J., Ebling, M., Fischl, B., Longstreth, W. T., Greve, D., Schmidt, H., Nyquist, P., Vinke, L. N., Van Duijn, C. M., Xue, L., Mazoyer, B., Bis, J. C., Gudnason, V., Seshadri, S., Ikram, M. A., Martin, N. G., Wright, M. J., Schumann, G., Franke, B., Thompson, P. M. & Medland, S. E., Apr 9 2015, In : Nature. 520, 7546, p. 224-229 6 p.

Research output: Contribution to journalArticle

386 Scopus citations

Comprehensive gene- and pathway-based analysis of depressive symptoms in older adults

the Alzheimer's Disease Neuroimaging Initiative (ADNI), Jan 1 2015, In : Journal of Alzheimer's Disease. 45, 4, p. 1197-1206 10 p.

Research output: Contribution to journalArticle

17 Scopus citations

Comprehensive gene- and pathway-based analysis of depressive symptoms in older adults

Alzheimer’s Disease Neuroimaging Initiative (ADNI), Jan 1 2015, Handbook of Depression in Alzheimer's Disease. IOS Press, p. 313-322 10 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

Comprehensive Gene- and Pathway-Based Analysis of Depressive Symptoms in Older Adults

Nho, K., Ramanan, V. K., Horgusluoglu, E., Kim, S., Inlow, M. H., Risacher, S. L., McDonald, B. C., Farlow, M. R., Foroud, T. M., Gao, S., Callahan, C. M., Hendrie, H. C., Niculescu, A. B. & Saykin, A. J., Jan 1 2015, Handbook of Depression in Alzheimer's Disease. Smith, G. S. (ed.). IOS Press, p. 313-322 10 p. (Advances in Alzheimer's Disease; vol. 4).

Research output: Chapter in Book/Report/Conference proceedingChapter

1 Scopus citations

Critical role of phosphorylation of serine 165 of YBX1 on the activation of NF-κB in colon cancer

Prabhu, L., Mundade, R., Wang, B., Wei, H., Hartley, A. V., Martin, M., McElyea, K., Temm, C. J., Sandusky, G., Liu, Y. & Lu, T., Jan 1 2015, In : Oncotarget. 6, 30, p. 29396-29412 17 p.

Research output: Contribution to journalArticle

17 Scopus citations