Medical & Molecular Genetics

Publications

Article

Differences in vector-genome processing and illegitimate integration of non-integrating lentiviral vectors

Shaw, A. M., Joseph, G. L., Jasti, A. C., Sastry-Dent, L., Witting, S. & Cornetta, K., Oct 20 2016, (Accepted/In press) In : Gene Therapy.

Research output: Contribution to journalArticle

3 Scopus citations

Different DNA lesions trigger distinct cell death responses in HCT116 colon carcinoma cells

Bai, S. & Goodrich, D. W., May 1 2004, In : Molecular cancer therapeutics. 3, 5, p. 613-619 7 p.

Research output: Contribution to journalArticle

9 Scopus citations

Differential gene induction by type I and type II interferons and their combination

Sanda, C., Weitzel, P., Tsukahara, T., Schaley, J., Edenberg, H. J., Stephens, M. A., McClintick, J. N., Blatt, L. M., Li, L., Brodsky, L. & Taylor, M. W., Jul 1 2006, In : Journal of Interferon and Cytokine Research. 26, 7, p. 462-472 11 p.

Research output: Contribution to journalArticle

79 Scopus citations

Differentially expressed genes strongly correlated with femur strength in rats

Alam, I., Sun, Q., Koller, D. L., Liu, L., Liu, Y., Edenberg, H. J., Li, J., Foroud, T. & Turner, C. H., Oct 1 2009, In : Genomics. 94, 4, p. 257-262 6 p.

Research output: Contribution to journalArticle

7 Scopus citations

Different mutations in the same codon of the proteolipid protein gene, PLP, may help in correlating genotype with phenotype in Pelizaeus-Merzbacher disease/X-linked spastic paraplegia (PMD/SPG2)

Hodes, M. E., Zimmerman, A. W., Aydanian, A., Naidu, S., Miller, N. R., Garcia Oller, J. L., Barker, B., Aleck, K. A., Hurley, T. D. & Dlouhy, S. R., Jan 15 1999, In : American journal of medical genetics. 82, 2, p. 132-139 8 p.

Research output: Contribution to journalArticle

27 Scopus citations

Diffusion-weighted imaging of white matter abnormalities in patients with phenylketonuria

Phillips, M. D., McGraw, P., Lowe, M. J., Mathews, V. P. & Hainline, B. E., Sep 27 2001, In : American Journal of Neuroradiology. 22, 8, p. 1583-1586 4 p.

Research output: Contribution to journalArticle

70 Scopus citations

Direct cDNA selection with DNA microdissected from mouse chromosome 16: Isolation of novel clones and construction of a partial transcription map of the C3-C4 region

Wei, J., Hodes, M. E., Wang, Y., Feng, Y., Ghetti, B. & Dlouhy, S. R., Aug 1996, In : Genome research. 6, 8, p. 678-687 10 p.

Research output: Contribution to journalArticle

Open Access
8 Scopus citations

Disabled-2 downregulation promotes epithelial-to-mesenchymal transition

Martin, J. C., Herbert, B. S. & Hocevar, B. A., Nov 23 2010, In : British Journal of Cancer. 103, 11, p. 1716-1723 8 p.

Research output: Contribution to journalArticle

27 Scopus citations

Disclosure of APOE genotype for risk of Alzheimer's disease

Green, R. C., Roberts, J. S., Cupples, L. A., Relkin, N. R., Whitehouse, P. J., Brown, T., Eckert, S. L., Butson, M., Sadovnick, A. D., Quaid, K. A., Chen, C., Cook-Deegan, R. & Farrer, L. A., Jul 16 2009, In : New England Journal of Medicine. 361, 3, p. 245-254 10 p.

Research output: Contribution to journalArticle

308 Scopus citations

Discriminatory Indices of Typing Methods for Epidemiologic Analysis of Contemporary Staphylococcus aureus Strains

Rodriguez, M., Hogan, P. G., Satola, S. W., Crispell, E., Wylie, T., Gao, H., Sodergren, E., Weinstock, G. M., Burnham, C. A. D. & Fritz, S. A., Sep 1 2015, In : Medicine. 94, 37, p. e1534

Research output: Contribution to journalArticle

21 Scopus citations

Disease progression-dependent effects of TREM2 deficiency in a mouse model of Alzheimer's disease

Jay, T. R., Hirsch, A. M., Broihier, M. L., Miller, C. M., Neilson, L. E., Ransohoff, R. M., Lamb, B. T. & Landreth, G. E., Jan 18 2017, In : Journal of Neuroscience. 37, 3, p. 637-647 11 p.

Research output: Contribution to journalArticle

Open Access
137 Scopus citations

Disentangling the genetics of lean mass

Karasik, D., Zillikens, M. C., Hsu, Y. H., Aghdassi, A., Akesson, K., Amin, N., Barroso, I., Bennett, D. A., Bertram, L., Bochud, M., Borecki, I. B., Broer, L., Buchman, A. S., Byberg, L., Campbell, H., Campos-Obando, N., Cauley, J. A., Cawthon, P. M., Chambers, J. C., Chen, Z. & 137 others, Cho, N. H., Choi, H. J., Chou, W. C., Cummings, S. R., De Groot, L. C. P. G. M., De Jager, P. L., Demuth, I., Diatchenko, L., Econs, M. J., Eiriksdottir, G., Enneman, A. W., Eriksson, J., Eriksson, J. G., Estrada, K., Evans, D. S., Feitosa, M. F., Fu, M., Gieger, C., Grallert, H., Gudnason, V., Lenore, L. J., Hayward, C., Hofman, A., Homuth, G., Huffman, K. M., Husted, L. B., Illig, T., Ingelsson, E., Ittermann, T., Jansson, J. O., Johnson, T., Biffar, R., Jordan, J. M., Jula, A., Karlsson, M., Khaw, K. T., Kilpeläinen, T. O., Klopp, N., Kloth, J. S. L., Koller, D. L., Kooner, J. S., Kraus, W. E., Kritchevsky, S., Kutalik, Z., Kuulasmaa, T., Kuusisto, J., Laakso, M., Lahti, J., Lang, T., Langdahl, B. L., Lerch, M. M., Lewis, J. R., Lill, C., Lind, L., Lindgren, C., Liu, Y., Livshits, G., Ljunggren, Ö., Loos, R. J. F., Lorentzon, M., Luan, JA., Luben, R. N., Malkin, I., McGuigan, F. E., Medina-Gomez, C., Meitinger, T., Melhus, H., Mellström, D., Michaëlsson, K., Mitchell, B. D., Morris, A. P., Mosekilde, L., Nethander, M., Newman, A. B., Oconnell, J. R., Oostra, B. A., Orwoll, E. S., Palotie, A., Peacock, M., Perola, M., Peters, A., Prince, R. L., Psaty, B. M., Räikkönen, K., Ralston, S. H., Ripatti, S., Rivadeneira, F., Robbins, J. A., Rotter, J. I., Rudan, I., Salomaa, V., Satterfield, S., Schipf, S., Shin, C. S., Smith, A. V., Smith, S. B., Soranzo, N., Spector, T. D., StanÄ Áková, A., Stefansson, K., Steinhagen-Thiessen, E., Stolk, L., Streeten, E. A., Styrkarsdottir, U., Swart, K. M. A., Thompson, P., Thomson, C. A., Thorleifsson, G., Thorsteinsdottir, U., Tikkanen, E., Tranah, G. J., Uitterlinden, A. G., Van Duijn, C. M., Van Schoor, N. M., Vandenput, L., Vollenweider, P., Völzke, H., Wactawski-Wende, J., Walker, M., J Wareham, N., Waterworth, D., Weedon, M. N., Wichmann, H. E., Widen, E., Williams, F. M. K., Wilson, J. F., Wright, N. C., Yerges-Armstrong, L. M., Yu, L., Zhang, W., Zhao, J. H., Zhou, Y., Nielson, C. M., Harris, T. B., Demissie, S., Kiel, D. P. & Ohlsson, C., Feb 1 2019, In : American Journal of Clinical Nutrition. 109, 2, p. 276-278 3 p.

Research output: Contribution to journalArticle

10 Scopus citations

Disorders of phosphate metabolism

DiMeglio, L. A., White, K. E. & Econs, M. J., Jan 1 2000, In : Endocrinology and Metabolism Clinics of North America. 29, 3, p. 591-609 19 p.

Research output: Contribution to journalArticle

41 Scopus citations

Disparate effects of telomere attrition on gene expression during replicative senescence of human mammary epithelial cells cultured under different conditions

Zhang, H., Herbert, B. S., Pan, K. H., Shay, J. W. & Cohen, S. N., Aug 19 2004, In : Oncogene. 23, 37, p. 6193-6198 6 p.

Research output: Contribution to journalArticle

25 Scopus citations

Disruption of Aedes aegypti Olfactory System Development through Chitosan/siRNA Nanoparticle Targeting of semaphorin-1a

Mysore, K., Flannery, E. M., Tomchaney, M., Severson, D. W. & Duman-Scheel, M., May 2013, In : PLoS neglected tropical diseases. 7, 5, e2215.

Research output: Contribution to journalArticle

35 Scopus citations
57 Scopus citations

Diverse cell death pathways result from a single missense mutation in weaver mouse

Migheli, A., Piva, R., Wei, J., Attanasio, A., Casolino, S., Hodes, M. E., Dlouhy, S. R., Bayer, S. A. & Ghetti, B., Dec 1 1997, In : American Journal of Pathology. 151, 6, p. 1629-1638 10 p.

Research output: Contribution to journalArticle

39 Scopus citations

Diverse gene expression and DNA methylation profiles correlate with differential adaptation of breast cancer cells to the antiestrogens tamoxifen and fulvestrant

Fan, M., Yan, P. S., Hartman-Frey, C., Chen, L., Paik, H., Oyer, S. L., Salisbury, J. D., Cheng, A. S. L., Li, L., Abbosh, P. H., Huang, T. H. M. & Nephew, K. P., Dec 15 2006, In : Cancer Research. 66, 24, p. 11954-11966 13 p.

Research output: Contribution to journalArticle

176 Scopus citations

Diverse spatial, temporal, and sexual expression of recently duplicated androgen-binding protein genes in Mus musculus

Laukaitis, C. M., Dlouhy, S. R., Emes, R. D., Ponting, C. P. & Karn, R. C., Jul 14 2005, In : BMC Evolutionary Biology. 5

Research output: Contribution to journalArticle

25 Scopus citations

DksA and (p)ppGpp have unique and overlapping contributions to Haemophilus ducreyi pathogenesis in humans

Holley, C. L., Zhang, X., Fortney, K. R., Ellinger, S., Johnson, P., Baker, B., Liu, Y., Janowicz, D. M., Katz, B. P., Munson, R. S. & Spinola, S. M., Jan 1 2015, In : Infection and immunity. 83, 8, p. 3281-3292 12 p.

Research output: Contribution to journalArticle

12 Scopus citations

DNA damage-induced phosphorylation of the human telomere-associated protein TRF2

Tanaka, H., Mendonca, M. S., Bradshaw, P. S., Hoelz, D. J., Malkas, L. H., Meyn, M. S. & Gilley, D., Oct 25 2005, In : Proceedings of the National Academy of Sciences of the United States of America. 102, 43, p. 15539-15544 6 p.

Research output: Contribution to journalArticle

74 Scopus citations
30 Scopus citations

DNA methyltransferase inhibition reduces inflammation-induced colon tumorigenesis

Maiuri, A. R., Savant, S. S., Podicheti, R., Rusch, D. B. & O’Hagan, H. M., Dec 2 2019, In : Epigenetics. 14, 12, p. 1209-1223 15 p.

Research output: Contribution to journalArticle

2 Scopus citations

DNA-PKcs is critical for telomere capping

Gilley, D., Tanaka, H., Hande, M. P., Kurimasa, A., Li, G. C., Oshimura, M. & Chen, D. J., Dec 18 2001, In : Proceedings of the National Academy of Sciences of the United States of America. 98, 26, p. 15084-15088 5 p.

Research output: Contribution to journalArticle

147 Scopus citations

DNM3 and genetic modifiers of age of onset in LRRK2 Gly2019Ser parkinsonism: a genome-wide linkage and association study

Trinh, J., Gustavsson, E. K., Vilariño-Güell, C., Bortnick, S., Latourelle, J., McKenzie, M. B., Tu, C. S., Nosova, E., Khinda, J., Milnerwood, A., Lesage, S., Brice, A., Tazir, M., Aasly, J. O., Parkkinen, L., Haytural, H., Foroud, T., Myers, R. H., Sassi, S. B., Hentati, E. & 5 others, Nabli, F., Farhat, E., Amouri, R., Hentati, F. & Farrer, M. J., Nov 1 2016, In : The Lancet Neurology. 15, 12, p. 1248-1256 9 p.

Research output: Contribution to journalArticle

32 Scopus citations

Dopaminergic parameters in the striatum and substantia nigra of seven strains of mice: Higher density in striatum of CAST compared to BALB mice

Richter, J. A., Brenneman, M. G., Dlouhy, S. R. & Ghetti, B., Apr 1 1995, In : Neurochemical Research. 20, 4, p. 395-400 6 p.

Research output: Contribution to journalArticle

1 Scopus citations

Dose-intensification of procarbazine, CCNU (lomustine), vincristine (PCV) with peripheral blood stem cell support in young patients with gliomas

Jakacki, R. I., Jamison, C., Mathews, V. P., Hellman, D. K., Dropcho, E., Cornetta, K., Macdonald, D. R. & Williams, D. A., Dec 5 1998, In : Medical and Pediatric Oncology. 31, 6, p. 483-490 8 p.

Research output: Contribution to journalArticle

18 Scopus citations

Downregulation of Organic Anion Transporting Polypeptide (OATP) 1B1 Transport Function by Lysosomotropic Drug Chloroquine: Implication in OATP-Mediated Drug-Drug Interactions

Alam, K., Pahwa, S., Wang, X., Zhang, P., Ding, K., Abuznait, A. H., Li, L. & Yue, W., Mar 7 2016, In : Molecular Pharmaceutics. 13, 3, p. 839-851 13 p.

Research output: Contribution to journalArticle

13 Scopus citations

Drug-drug interaction prediction: A Bayesian meta-analysis approach

Li, L., Yu, M., Chin, R., Lucksiri, A., Flockhart, D. A. & Hall, S. D., Sep 10 2007, In : Statistics in Medicine. 26, 20, p. 3700-3721 22 p.

Research output: Contribution to journalArticle

18 Scopus citations

Drug-drug interaction prediction assessment

Zhou, J., Qin, Z., Sara, Q. K., Kim, S., Wang, Z., Hall, S. D. & Li, L., Jul 1 2009, In : Journal of biopharmaceutical statistics. 19, 4, p. 641-657 17 p.

Research output: Contribution to journalArticle

1 Scopus citations

Dynamic regulation of FGF23 by Fam20C phosphorylation, GalNAc-T3 glycosylation, and furin proteolysis

Tagliabracci, V. S., Engel, J. L., Wiley, S. E., Xiao, J., Gonzalez, D. J., Appaiah, H. N., Koller, A., Nizet, V., White, K. E. & Dixon, J. E., Apr 15 2014, In : Proceedings of the National Academy of Sciences of the United States of America. 111, 15, p. 5520-5525 6 p.

Research output: Contribution to journalArticle

142 Scopus citations

Early-onset Alzheimer disease caused by a new mutation (V717L) in the amyloid precursor protein gene

Murrell, J. R., Hake, A. M., Quaid, K. A., Farlow, M. R. & Ghetti, B., Jun 2000, In : Archives of Neurology. 57, 6, p. 885-887 3 p.

Research output: Contribution to journalArticle

Open Access
69 Scopus citations

Early role of vascular dysregulation on late-onset Alzheimer's disease based on multifactorial data-driven analysis

The Alzheimer's Disease Neuroimaging Initiative, Jun 21 2016, In : Nature communications. 7, 11934.

Research output: Contribution to journalArticle

275 Scopus citations

Ectopic cell cycle events link human Alzheimer's disease and amyloid precursor protein transgenic mouse models

Yang, Y., Varvel, N. H., Lamb, B. T. & Herrup, K., Jan 18 2006, In : Journal of Neuroscience. 26, 3, p. 775-784 10 p.

Research output: Contribution to journalArticle

143 Scopus citations

Effect of cirrhosis and liver transplantation on the gender difference in QT interval

Adigun, A. Q., Pinto, A. G., Flockhart, D. A., Gorski, J. C., Li, L., Hall, S. D. & Chalasani, N., Mar 1 2005, In : American Journal of Cardiology. 95, 5, p. 691-694 4 p.

Research output: Contribution to journalArticle

23 Scopus citations

Effects of chronic intermittent ethanol exposure and withdrawal on neuroblastoma cell transcriptome

McClintick, J. N., Thapa, K., Liu, Y., Xuei, X. & Edenberg, H. J., Jun 2020, In : Alcohol. 85, p. 119-126 8 p.

Research output: Contribution to journalArticle

Effects of exemestane and letrozole therapy on plasma concentrations of estrogens in a randomized trial of postmenopausal women with breast cancer

Robarge, J. D., Desta, Z., Nguyen, A. T., Li, L., Hertz, D., Rae, J. M., Hayes, D. F., Storniolo, A. M., Stearns, V., Flockhart, D. A., Skaar, T. C. & Henry, N. L., Feb 1 2017, In : Breast Cancer Research and Treatment. 161, 3, p. 453-461 9 p.

Research output: Contribution to journalArticle

7 Scopus citations

Effects of glucose metabolism on the regulation of genes of fatty acid synthesis and triglyceride secretion in the liver

Morral, N., Edenberg, H. J., Witting, S. R., Altomonte, J., Chu, T. & Brown, M., Jul 1 2007, In : Journal of Lipid Research. 48, 7, p. 1499-1510 12 p.

Research output: Contribution to journalArticle

36 Scopus citations

Effects of high-impact mechanical loading on synovial cell cultures

Sun, I., Liu, Y., Tanaka, S. M., Lee, C. W., Sun, H. B. & Yokota, H., Dec 1 2004, In : Journal of Sports Science and Medicine. 3, 1, p. 37-43 7 p.

Research output: Contribution to journalArticle

2 Scopus citations

Effects of HIV protease inhibitor ritonavir on Akt-regulated cell proliferation in breast cancer

Srirangam, A., Mitra, R., Wang, M., Gorski, J. C., Badve, S., Baldridge, L. A., Hamilton, J., Kishimoto, H., Hawes, J., Li, L., Orschell, C. M., Srour, E. F., Blum, J. S., Donner, D., Sledge, G. W., Nakshatri, H. & Potter, D. A., Mar 15 2006, In : Clinical Cancer Research. 12, 6, p. 1883-1896 14 p.

Research output: Contribution to journalArticle

69 Scopus citations

Efficient and stable gene expression into human osteoclasts using an HIV-1-based lentiviral vector

Chu, K., Cornetta, K. G. & Econs, M. J., Jun 1 2008, In : DNA and Cell Biology. 27, 6, p. 315-320 6 p.

Research output: Contribution to journalArticle

7 Scopus citations

Efficient large volume lentiviral vector production using flow electroporation

Witting, S. R., Li, L. H., Jasti, A., Allen, C., Cornetta, K., Brady, J., Shivakumar, R. & Peshwa, M. V., Feb 1 2012, In : Human gene therapy. 23, 2, p. 243-249 7 p.

Research output: Contribution to journalArticle

22 Scopus citations

Efficient region-based test strategy uncovers genetic risk factors for functional outcome in bipolar disorder

Budde, M., Friedrichs, S., Alliey-Rodriguez, N., Ament, S., Badner, J. A., Berrettini, W. H., Bloss, C. S., Byerley, W., Cichon, S., Comes, A. L., Coryell, W., Craig, D. W., Degenhardt, F., Edenberg, H. J., Foroud, T., Forstner, A. J., Frank, J., Gershon, E. S., Goes, F. S., Greenwood, T. A. & 40 others, Guo, Y., Hipolito, M., Hood, L., Keating, B. J., Koller, D. L., Lawson, W. B., Liu, C., Mahon, P. B., McInnis, M. G., McMahon, F. J., Meier, S. M., Mühleisen, T. W., Murray, S. S., Nievergelt, C. M., Nurnberger, J. I., Nwulia, E. A., Potash, J. B., Quarless, D., Rice, J., Roach, J. C., Scheftner, W. A., Schork, N. J., Shekhtman, T., Shilling, P. D., Smith, E. N., Streit, F., Strohmaier, J., Szelinger, S., Treutlein, J., Witt, S. H., Zandi, P. P., Zhang, P., Zöllner, S., Bickeböller, H., Falkai, P. G., Kelsoe, J. R., Nöthen, M. M., Rietschel, M., Schulze, T. G. & Malzahn, D., Jan 2019, In : European Neuropsychopharmacology. 29, 1, p. 156-170 15 p.

Research output: Contribution to journalArticle

Open Access
1 Scopus citations

Efficient retrovirus-mediated transfer of the multidrug resistance 1 gene into autologous human long-term repopulating hematopoietic stem cells

Abonour, R., Williams, D. A., Einhorn, L., Hall, K. M., Chen, J., Coffman, J., Traycoff, C. M., Bank, A., Kato, I., Ward, M., Williams, S. D., Hromas, R., Robertson, M. J., Smith, F. O., Woo, D., Mills, B., Srour, E. F. & Cornetta, K., Jun 1 2000, In : Nature Medicine. 6, 6, p. 652-658 7 p.

Research output: Contribution to journalArticle

239 Scopus citations

Elevated expression of cancer-associated proliferating cell nuclear antigen in high-grade prostatic intraepithelial neoplasia and prostate cancer

Wang, X., Hickey, R. J., Malkas, L. H., Koch, M. O., Li, L., Zhang, S., Sandusky, G. E., Grignon, D. J., Eble, J. N. & Cheng, L., May 15 2011, In : Prostate. 71, 7, p. 748-754 7 p.

Research output: Contribution to journalArticle

17 Scopus citations

Elevated vitamin D receptor levels in genetic hypercalciuric stone-forming rats are associated with downregulation of snail

Bai, S., Wang, H., Shen, J., Zhou, R., Bushinsky, D. A. & Favus, M. J., Apr 2010, In : Journal of Bone and Mineral Research. 25, 4, p. 830-840 11 p.

Research output: Contribution to journalArticle

22 Scopus citations

Embryonic stem cells attenuate myocardial dysfunction and inflammation after surgical global ischemia via paracrine actions

Crisostomo, P. R., Abarbanell, A. M., Wang, M., Lahm, T., Wang, Y. & Meldrum, D. R., Oct 1 2008, In : American Journal of Physiology - Heart and Circulatory Physiology. 295, 4, p. H1726-H1735

Research output: Contribution to journalArticle

60 Scopus citations

Empirical bayes model comparisons for differential methylation analysis

Teng, M., Wang, Y., Kim, S., Li, L., Shen, C., Wang, G., Liu, Y., Huang, T. H. M., Nephew, K. P. & Balch, C., 2012, In : Comparative and Functional Genomics. 2012, 376706.

Research output: Contribution to journalArticle

1 Scopus citations

Endocrine and genetic characterization of cousins with male pseudohermaphroditism: evidence that the Lubs pheno‐type can result from a mutation that alters the structure of the androgen receptor

Wilson, J. D., Carlson, B. R., Weaver, D. D., Kovacs, W. J. & Griffin, J. E., Oct 1984, In : Clinical Genetics. 26, 4, p. 363-370 8 p.

Research output: Contribution to journalArticle

2 Scopus citations

Endophenotypes successfully lead to gene identification: Results from the collaborative study on the genetics of alcoholism

Dick, D. M., Jones, K., Saccone, N., Hinrichs, A., Wang, J. C., Goate, A., Bierut, L., Almasy, L., Schuckit, M., Hesselbrock, V., Tischfield, J., Foroud, T., Edenberg, H., Porjesz, B. & Begleiter, H., Jan 1 2006, In : Behavior Genetics. 36, 1, p. 112-126 15 p.

Research output: Contribution to journalArticle

84 Scopus citations