Medical & Molecular Genetics

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2020

Assessment of executive function declines in presymptomatic and mildly symptomatic familial frontotemporal dementia: NIH-EXAMINER as a potential clinical trial endpoint

on behalf of the ARTFL/LEFFTDS consortium, Jan 1 2020, In : Alzheimer's and Dementia. 16, 1, p. 11-21 11 p.

Research output: Contribution to journalArticle

Open Access
2 Scopus citations

Clinical and volumetric changes with increasing functional impairment in familial frontotemporal lobar degeneration

on behalf of the ARTFL and LEFFTDS consortia, Jan 1 2020, In : Alzheimer's and Dementia. 16, 1, p. 49-59 11 p.

Research output: Contribution to journalArticle

Open Access

Clinical spectrum of individuals with pathogenic NF1 missense variants affecting p.Met1149, p.Arg1276, and p.Lys1423: genotype–phenotype study in neurofibromatosis type 1

Koczkowska, M., Callens, T., Chen, Y., Gomes, A., Hicks, A. D., Sharp, A., Johns, E., Uhas, K. A., Armstrong, L., Bosanko, K. A., Babovic-Vuksanovic, D., Baker, L., Basel, D. G., Bengala, M., Bennett, J. T., Chambers, C., Clarkson, L. K., Clementi, M., Cortés, F. M., Cunningham, M. & 88 others, D'Agostino, M. D., Delatycki, M. B., Digilio, M. C., Dosa, L., Esposito, S., Fox, S., Freckmann, M. L., Fauth, C., Giugliano, T., Giustini, S., Goetsch, A., Goldberg, Y., Greenwood, R. S., Griffis, C., Gripp, K. W., Gupta, P., Haan, E., Hachen, R. K., Haygarth, T. L., Hernández-Chico, C., Hodge, K., Hopkin, R. J., Hudgins, L., Janssens, S., Keller, K., Kelly-Mancuso, G., Kochhar, A., Korf, B. R., Lewis, A. M., Liebelt, J., Lichty, A., Listernick, R. H., Lyons, M. J., Maystadt, I., Martinez Ojeda, M., McDougall, C., McGregor, L. K., Melis, D., Mendelsohn, N., Nowaczyk, M. J. M., Ortenberg, J., Panzer, K., Pappas, J. G., Pierpont, M. E., Piluso, G., Pinna, V., Pivnick, E. K., Pond, D. A., Powell, C. M., Rogers, C., Ruhrman Shahar, N., Rutledge, S. L., Saletti, V., Sandaradura, S. A., Santoro, C., Schatz, U. A., Schreiber, A., Scott, D. A., Sellars, E. A., Sheffer, R., Siqveland, E., Slopis, J. M., Smith, R., Spalice, A., Stockton, D. W., Streff, H., Theos, A., Tomlinson, G. E., Tran, G., Trapane, P. L., Trevisson, E., Ullrich, N. J., Van den Ende, J., Schrier Vergano, S. A., Wallace, S. E., Wangler, M. F., Weaver, D. D., Yohay, K. H., Zackai, E., Zonana, J., Zurcher, V., Claes, K. B. M., Eoli, M., Martin, Y., Wimmer, K., De Luca, A., Legius, E. & Messiaen, L. M., Jan 1 2020, In : Human Mutation. 41, 1, p. 299-315 17 p.

Research output: Contribution to journalArticle

Open Access
2 Scopus citations
1 Scopus citations

Exome-chip association analysis of intracranial aneurysms

van 't Hof, F. N. G., Lai, D., van Setten, J., Bots, M. L., Vaartjes, I., Broderick, J., Woo, D., Foroud, T., Rinkel, G. J. E., de Bakker, P. I. W. & Ruigrok, Y. M., Feb 4 2020, In : Neurology. 94, 5, p. e481-e488

Research output: Contribution to journalArticle

Genome-wide association studies of the self-rating of effects of ethanol (SRE)

Lai, D., Wetherill, L., Kapoor, M., Johnson, E. C., Schwandt, M., Ramchandani, V. A., Goldman, D., Joslyn, G., Rao, X., Liu, Y., Farris, S., Mayfield, R. D., Dick, D., Hesselbrock, V., Kramer, J., McCutcheon, V. V., Nurnberger, J., Tischfield, J., Goate, A., Edenberg, H. J. & 4 others, Porjesz, B., Agrawal, A., Foroud, T. & Schuckit, M., Mar 1 2020, In : Addiction Biology. 25, 2, e12800.

Research output: Contribution to journalArticle

Sestrin 3 Protects Against Diet-Induced Nonalcoholic Steatohepatitis in Mice Through Suppression of Transforming Growth Factor β Signal Transduction

Huang, M., Kim, H. G., Zhong, X., Dong, C., Zhang, B., Fang, Z., Zhang, Y., Lu, X., Saxena, R., Liu, Y., Zhang, C., Liangpunsakul, S. & Dong, X. C., Jan 1 2020, In : Hepatology. 71, 1, p. 76-92 17 p.

Research output: Contribution to journalArticle

1 Scopus citations

The longitudinal evaluation of familial frontotemporal dementia subjects protocol: Framework and methodology

on Behalf of the LEFFTDS Consortium, Jan 1 2020, In : Alzheimer's and Dementia. 16, 1, p. 22-36 15 p.

Research output: Contribution to journalArticle

Open Access
2 Scopus citations
2019

Allele-specific expression and high-throughput reporter assay reveal functional genetic variants associated with alcohol use disorders

Rao, X., Thapa, K. S., Chen, A. B., Lin, H., Gao, H., Reiter, J. L., Hargreaves, K. A., Ipe, J., Lai, D., Xuei, X., Wang, Y., Gu, H., Kapoor, M., Farris, S. P., Tischfield, J., Foroud, T., Goate, A. M., Skaar, T. C., Mayfield, R. D., Edenberg, H. J. & 1 others, Liu, Y., Jan 1 2019, (Accepted/In press) In : Molecular Psychiatry.

Research output: Contribution to journalArticle

1 Scopus citations

Analysis of whole genome-transcriptomic organization in brain to identify genes associated with alcoholism

Kapoor, M., Wang, J. C., Farris, S. P., Liu, Y., McClintick, J., Gupta, I., Meyers, J. L., Bertelsen, S., Chao, M., Nurnberger, J., Tischfield, J., Harari, O., Zeran, L., Hesselbrock, V., Bauer, L., Raj, T., Porjesz, B., Agrawal, A., Foroud, T., Edenberg, H. J. & 2 others, Mayfield, R. D. & Goate, A., Dec 1 2019, In : Translational psychiatry. 9, 1, 89.

Research output: Contribution to journalArticle

6 Scopus citations

Angiotensin-related genetic determinants of cardiovascular disease in patients undergoing hemodialysis

Moe, S. M., Long, J., Schwantes-An, T. H. L., Decker, B. S., Wetherill, L., Edenberg, H. J., Xuei, X., Vatta, M., Foroud, T. M. & Chertow, G. M., Nov 1 2019, In : Nephrology Dialysis Transplantation. 34, 11, p. 1924-1931 8 p.

Research output: Contribution to journalArticle

Open Access

A nonsynonymous mutation in PLCG2 reduces the risk of Alzheimer’s disease, dementia with Lewy bodies and frontotemporal dementia, and increases the likelihood of longevity

DESGESCO (Dementia Genetics Spanish Consortium), EADB (Alzheimer Disease European DNA biobank), EADB (Alzheimer Disease European DNA biobank), IFGC (International FTD-Genomics Consortium), IPDGC (The International Parkinson Disease Genomics Consortium), IPDGC (The International Parkinson Disease Genomics Consortium), RiMod-FTD (Risk and Modifying factors in Fronto-Temporal Dementia), Netherlands Brain Bank (NBB) & The GIFT (Genetic Investigation in Frontotemporal Dementia and Alzheimer’s Disease) Study Group, Aug 1 2019, In : Acta Neuropathologica. 138, 2, p. 237-250 14 p.

Research output: Contribution to journalArticle

Open Access
12 Scopus citations

An unusual cause for Coffin–Lowry syndrome: Three brothers with a novel microduplication in RPS6KA3

Castelluccio, V. J., Vetrini, F., Lynnes, T., Jones, J., Holloway, L., Belonis, A., Breman, A. M., Graham, B. H., Sapp, K., Wilson, T., Schwartz, C. E., Pratt, V. M. & Weaver, D. D., Dec 1 2019, In : American Journal of Medical Genetics, Part A. 179, 12, p. 2357-2364 8 p.

Research output: Contribution to journalArticle

A rare missense variant of CASP7 is associated with familial late-onset Alzheimer's disease

Alzheimer's Disease Sequencing Project, Mar 2019, In : Alzheimer's and Dementia. 15, 3, p. 441-452 12 p.

Research output: Contribution to journalArticle

Open Access
5 Scopus citations

Association of polygenic liability for alcohol dependence and EEG connectivity in adolescence and young adulthood

Meyers, J. L., Chorlian, D. B., Johnson, E. C., Pandey, A. K., Kamarajan, C., Salvatore, J. E., Aliev, F., de Viteri, S. S. S., Zhang, J., Chao, M., Kapoor, M., Hesselbrock, V., Kramer, J., Kuperman, S., Nurnberger, J., Tischfield, J., Goate, A., Foroud, T., Dick, D. M., Edenberg, H. J. & 2 others, Agrawal, A. & Porjesz, B., Oct 2019, In : Brain Sciences. 9, 10, 280.

Research output: Contribution to journalArticle

Open Access
1 Scopus citations

Astrocytes Regulate the Development and Maturation of Retinal Ganglion Cells Derived from Human Pluripotent Stem Cells

VanderWall, K. B., Vij, R., Ohlemacher, S. K., Sridhar, A., Fligor, C. M., Feder, E. M., Edler, M. C., Baucum, A. J., Cummins, T. R. & Meyer, J. S., Feb 12 2019, In : Stem Cell Reports. 12, 2, p. 201-212 12 p.

Research output: Contribution to journalArticle

2 Scopus citations

BERMUDA: A novel deep transfer learning method for single-cell RNA sequencing batch correction reveals hidden high-resolution cellular subtypes

Wang, T., Johnson, T. S., Shao, W., Lu, Z., Helm, B. R., Zhang, J. & Huang, K., Aug 12 2019, In : Genome biology. 20, 1, 165.

Research output: Contribution to journalArticle

Open Access
4 Scopus citations

Bipolar multiplex families have an increased burden of common risk variants for psychiatric disorders

Bipolar Disorder Working Group of the Psychiatric Genomics Consortium & Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium, Jan 1 2019, (Accepted/In press) In : Molecular Psychiatry.

Research output: Contribution to journalArticle

Open Access

Blood biomarkers for memory: toward early detection of risk for Alzheimer disease, pharmacogenomics, and repurposed drugs

Niculescu, A. B., Le-Niculescu, H., Roseberry, K., Wang, S., Hart, J., Kaur, A., Robertson, H., Jones, T., Strasburger, A., Williams, A., Kurian, S. M., Lamb, B., Shekhar, A., Lahiri, D. K. & Saykin, A. J., Jan 1 2019, (Accepted/In press) In : Molecular Psychiatry.

Research output: Contribution to journalArticle

Open Access
1 Scopus citations

Cancer outcomes among Parkinson's disease patients with leucine rich repeat kinase 2 mutations, idiopathic Parkinson's disease patients, and nonaffected controls

Agalliu, I., Ortega, R. A., Luciano, M. S., Mirelman, A., Pont-Sunyer, C., Brockmann, K., Vilas, D., Tolosa, E., Berg, D., Warø, B., Glickman, A., Raymond, D., Inzelberg, R., Ruiz-Martinez, J., Mondragon, E., Friedman, E., Hassin-Baer, S., Alcalay, R. N., Mejia-Santana, H., Aasly, J. & 5 others, Foroud, T., Marder, K., Giladi, N., Bressman, S. & Saunders-Pullman, R., Sep 1 2019, In : Movement Disorders. 34, 9, p. 1392-1398 7 p.

Research output: Contribution to journalArticle

1 Scopus citations

Characterization of a broad-based mosquito yeast interfering RNA larvicide with a conserved target site in mosquito semaphorin-1a genes

Mysore, K., Li, P., Wang, C. W., Hapairai, L. K., Scheel, N. D., Realey, J. S., Sun, L., Severson, D. W., Wei, N. & Duman-Scheel, M., May 22 2019, In : Parasites and Vectors. 12, 1, 256.

Research output: Contribution to journalArticle

Open Access
1 Scopus citations

Characterization of a yeast interfering RNA larvicide with a target site conserved in the synaptotagmin gene of multiple disease vector mosquitoes

Mysore, K., Li, P., Wang, C. W., Hapairai, L. K., Scheel, N. D., Realey, J. S., Sun, L., Roethele, J. B., Severson, D. W., Wei, N. & Duman-Scheel, M., May 2019, In : PLoS neglected tropical diseases. 13, 5, e0007422.

Research output: Contribution to journalArticle

Open Access
1 Scopus citations

Comprehensive Cis-Regulation Analysis of Genetic Variants in Human Lymphoblastoid Cell Lines

Wang, Y., He, B., Zhao, Y., Reiter, J. L., Chen, S. X., Simpson, E., Feng, W. & Liu, Y., Sep 10 2019, In : Frontiers in Genetics. 10, 806.

Research output: Contribution to journalArticle

Open Access
1 Scopus citations

Correlation analysis of histopathology and proteogenomics data for breast cancer

Zhan, X., Cheng, J., Huang, Z., Han, Z., Helm, B., Liu, X., Zhang, J., Wang, T. F., Ni, D. & Huang, K., Jan 1 2019, In : Molecular and Cellular Proteomics. 18, 8, p. S37-S51

Research output: Contribution to journalArticle

Open Access
2 Scopus citations

Determination of an interaction network between an extracellular bacterial pathogen and the human host

Griesenauer, B., Tran, T. M., Fortney, K. R., Janowicz, D. M., Johnson, P., Gao, H., Barnes, S., Wilson, L. S., Liu, Y. & Spinola, S. M., May 1 2019, In : mBio. 10, 3, e01193-19.

Research output: Contribution to journalArticle

Open Access
3 Scopus citations

DNA methyltransferase inhibition reduces inflammation-induced colon tumorigenesis

Maiuri, A. R., Savant, S. S., Podicheti, R., Rusch, D. B. & O’Hagan, H. M., Dec 2 2019, In : Epigenetics. 14, 12, p. 1209-1223 15 p.

Research output: Contribution to journalArticle

1 Scopus citations

Efficient region-based test strategy uncovers genetic risk factors for functional outcome in bipolar disorder

Budde, M., Friedrichs, S., Alliey-Rodriguez, N., Ament, S., Badner, J. A., Berrettini, W. H., Bloss, C. S., Byerley, W., Cichon, S., Comes, A. L., Coryell, W., Craig, D. W., Degenhardt, F., Edenberg, H. J., Foroud, T., Forstner, A. J., Frank, J., Gershon, E. S., Goes, F. S., Greenwood, T. A. & 40 others, Guo, Y., Hipolito, M., Hood, L., Keating, B. J., Koller, D. L., Lawson, W. B., Liu, C., Mahon, P. B., McInnis, M. G., McMahon, F. J., Meier, S. M., Mühleisen, T. W., Murray, S. S., Nievergelt, C. M., Nurnberger, J. I., Nwulia, E. A., Potash, J. B., Quarless, D., Rice, J., Roach, J. C., Scheftner, W. A., Schork, N. J., Shekhtman, T., Shilling, P. D., Smith, E. N., Streit, F., Strohmaier, J., Szelinger, S., Treutlein, J., Witt, S. H., Zandi, P. P., Zhang, P., Zöllner, S., Bickeböller, H., Falkai, P. G., Kelsoe, J. R., Nöthen, M. M., Rietschel, M., Schulze, T. G. & Malzahn, D., Jan 2019, In : European Neuropsychopharmacology. 29, 1, p. 156-170 15 p.

Research output: Contribution to journalArticle

Open Access
1 Scopus citations

Exome Chip Meta-analysis Fine Maps Causal Variants and Elucidates the Genetic Architecture of Rare Coding Variants in Smoking and Alcohol Use

CHD Exome+ Consortium & Consortium for Genetics of Smoking Behaviour, Jun 1 2019, In : Biological psychiatry. 85, 11, p. 946-955 10 p.

Research output: Contribution to journalArticle

8 Scopus citations

Feasibility and safety of lumbar puncture in the Parkinson's disease research participants: Parkinson's Progression Marker Initiative (PPMI)

The Parkinson's Progression Markers InitiativeSteering Committee, Study Cores, Site Investigators, Coordinators & Industry and Scientific Advisory Board, May 2019, In : Parkinsonism and Related Disorders. 62, p. 201-209 9 p.

Research output: Contribution to journalArticle

1 Scopus citations

Fibroblast growth factor 23 genotype and cardiovascular disease in patients undergoing hemodialysis

Schwantes-An, T. H., Liu, S., Stedman, M., Decker, B. S., Wetherill, L., Edenberg, H. J., Vatta, M., Foroud, T. M., Chertow, G. M. & Moe, S. M., Feb 1 2019, In : American journal of nephrology. 49, 2, p. 125-132 8 p.

Research output: Contribution to journalArticle

2 Scopus citations

Gene co-expression networks restructured gene fusion in rhabdomyosarcoma cancers

Helm, B. R., Zhan, X., Pandya, P. H., Murray, M. E., Pollok, K. E., Renbarger, J. L., Ferguson, M. J., Han, Z., Ni, D., Zhang, J. & Huang, K., Sep 2019, In : Genes. 10, 9, 665.

Research output: Contribution to journalArticle

Open Access
2 Scopus citations

Generalized gene co-expression analysis via subspace clustering using low-rank representation

Wang, T., Zhang, J. & Huang, K., May 1 2019, In : BMC bioinformatics. 20, 196.

Research output: Contribution to journalArticle

Open Access

Genetic architecture of subcortical brain structures in 38,851 individuals

Satizabal, C. L., Adams, H. H. H., Hibar, D. P., White, C. C., Knol, M. J., Stein, J. L., Scholz, M., Sargurupremraj, M., Jahanshad, N., Roshchupkin, G. V., Smith, A. V., Bis, J. C., Jian, X., Luciano, M., Hofer, E., Teumer, A., van der Lee, S. J., Yang, J., Yanek, L. R., Lee, T. V. & 269 others, Li, S., Hu, Y., Koh, J. Y., Eicher, J. D., Desrivières, S., Arias-Vasquez, A., Chauhan, G., Athanasiu, L., Rentería, M. E., Kim, S., Hoehn, D., Armstrong, N. J., Chen, Q., Holmes, A. J., den Braber, A., Kloszewska, I., Andersson, M., Espeseth, T., Grimm, O., Abramovic, L., Alhusaini, S., Milaneschi, Y., Papmeyer, M., Axelsson, T., Ehrlich, S., Roiz-Santiañez, R., Kraemer, B., Håberg, A. K., Jones, H. J., Pike, G. B., Stein, D. J., Stevens, A., Bralten, J., Vernooij, M. W., Harris, T. B., Filippi, I., Witte, A. V., Guadalupe, T., Wittfeld, K., Mosley, T. H., Becker, J. T., Doan, N. T., Hagenaars, S. P., Saba, Y., Cuellar-Partida, G., Amin, N., Hilal, S., Nho, K., Mirza-Schreiber, N., Arfanakis, K., Becker, D. M., Ames, D., Goldman, A. L., Lee, P. H., Boomsma, D. I., Lovestone, S., Giddaluru, S., Le Hellard, S., Mattheisen, M., Bohlken, M. M., Kasperaviciute, D., Schmaal, L., Lawrie, S. M., Agartz, I., Walton, E., Tordesillas-Gutierrez, D., Davies, G. E., Shin, J., Ipser, J. C., Vinke, L. N., Hoogman, M., Jia, T., Burkhardt, R., Klein, M., Crivello, F., Janowitz, D., Carmichael, O., Haukvik, U. K., Aribisala, B. S., Schmidt, H., Strike, L. T., Cheng, C. Y., Risacher, S. L., Pütz, B., Fleischman, D. A., Assareh, A. A., Mattay, V. S., Buckner, R. L., Mecocci, P., Dale, A. M., Cichon, S., Boks, M. P., Matarin, M., Penninx, B. W. J. H., Calhoun, V. D., Chakravarty, M. M., Marquand, A. F., Macare, C., Kharabian Masouleh, S., Oosterlaan, J., Amouyel, P., Hegenscheid, K., Rotter, J. I., Schork, A. J., Liewald, D. C. M., de Zubicaray, G. I., Wong, T. Y., Shen, L., Sämann, P. G., Brodaty, H., Roffman, J. L., de Geus, E. J. C., Tsolaki, M., Erk, S., van Eijk, K. R., Cavalleri, G. L., van der Wee, N. J. A., McIntosh, A. M., Gollub, R. L., Bulayeva, K. B., Bernard, M., Richards, J. S., Himali, J. J., Loeffler, M., Rommelse, N., Hoffmann, W., Westlye, L. T., Valdés Hernández, M. C., Hansell, N. K., van Erp, T. G. M., Wolf, C., Kwok, J. B. J., Vellas, B., Heinz, A., Olde Loohuis, L. M., Delanty, N., Ho, B. C., Ching, C. R. K., Shumskaya, E., Singh, B., Hofman, A., van der Meer, D., Homuth, G., Psaty, B. M., Bastin, M. E., Montgomery, G. W., Foroud, T. M., Reppermund, S., Hottenga, J. J., Simmons, A., Meyer-Lindenberg, A., Cahn, W., Whelan, C. D., van Donkelaar, M. M. J., Yang, Q., Hosten, N., Green, R. C., Thalamuthu, A., Mohnke, S., Hulshoff Pol, H. E., Lin, H., Jack, C. R., Schofield, P. R., Mühleisen, T. W., Maillard, P., Potkin, S. G., Wen, W., Fletcher, E., Toga, A. W., Gruber, O., Huentelman, M., Davey Smith, G., Launer, L. J., Nyberg, L., Jönsson, E. G., Crespo-Facorro, B., Koen, N., Greve, D. N., Uitterlinden, A. G., Weinberger, D. R., Steen, V. M., Fedko, I. O., Groenewold, N. A., Niessen, W. J., Toro, R., Tzourio, C., Longstreth, W. T., Ikram, M. K., Smoller, J. W., van Tol, M. J., Sussmann, J. E., Paus, T., Lemaître, H., Schroeter, M. L., Mazoyer, B., Andreassen, O. A., Holsboer, F., Depondt, C., Veltman, D. J., Turner, J. A., Pausova, Z., Schumann, G., van Rooij, D., Djurovic, S., Deary, I. J., McMahon, K. L., Müller-Myhsok, B., Brouwer, R. M., Soininen, H., Pandolfo, M., Wassink, T. H., Cheung, J. W., Wolfers, T., Martinot, J. L., Zwiers, M. P., Nauck, M., Melle, I., Martin, N. G., Kanai, R., Westman, E., Kahn, R. S., Sisodiya, S. M., White, T., Saremi, A., van Bokhoven, H., Brunner, H. G., Völzke, H., Wright, M. J., van ‘t Ent, D., Nöthen, M. M., Ophoff, R. A., Buitelaar, J. K., Fernández, G., Sachdev, P. S., Rietschel, M., van Haren, N. E. M., Fisher, S. E., Beiser, A. S., Francks, C., Saykin, A. J., Mather, K. A., Romanczuk-Seiferth, N., Hartman, C. A., DeStefano, A. L., Heslenfeld, D. J., Weiner, M. W., Walter, H., Hoekstra, P. J., Nyquist, P. A., Franke, B., Bennett, D. A., Grabe, H. J., Johnson, A. D., Chen, C., van Duijn, C. M., Lopez, O. L., Fornage, M., Wardlaw, J. M., Schmidt, R., DeCarli, C., De Jager, P. L., Villringer, A., Debette, S., Gudnason, V., Medland, S. E., Shulman, J. M., Thompson, P. M., Seshadri, S. & Ikram, M. A., Nov 1 2019, In : Nature genetics. 51, 11, p. 1624-1636 13 p.

Research output: Contribution to journalArticle

4 Scopus citations

Genetic meta-analysis of diagnosed Alzheimer’s disease identifies new risk loci and implicates Aβ, tau, immunity and lipid processing

Alzheimer Disease Genetics Consortium (ADGC), The European Alzheimer’s Disease Initiative (EADI), Cohorts for Heart and Aging Research in Genomic Epidemiology Consortium (CHARGE), & Genetic and Environmental Risk in AD/Defining Genetic, Polygenic and Environmental Risk for Alzheimer’s Disease Consortium (GERAD/PERADES), Mar 1 2019, In : Nature genetics. 51, 3, p. 414-430 17 p.

Research output: Contribution to journalArticle

117 Scopus citations

Genome-wide association studies of alcohol dependence, DSM-IV criterion count and individual criteria

Lai, D., Wetherill, L., Bertelsen, S., Carey, C. E., Kamarajan, C., Kapoor, M., Meyers, J. L., Anokhin, A. P., Bennett, D. A., Bucholz, K. K., Chang, K. K., De Jager, P. L., Dick, D. M., Hesselbrock, V., Kramer, J., Kuperman, S., Nurnberger, J. I., Raj, T., Schuckit, M., Scott, D. M. & 9 others, Taylor, R. E., Tischfield, J., Hariri, A. R., Edenberg, H. J., Agrawal, A., Bogdan, R., Porjesz, B., Goate, A. M. & Foroud, T., Jul 2019, In : Genes, Brain and Behavior. 18, 6, e12579.

Research output: Contribution to journalArticle

6 Scopus citations

Genome-wide association study identifies 30 loci associated with bipolar disorder

eQTLGen Consortium, BIOS Consortium & the Bipolar Disorder Working Group of the Psychiatric Genomics Consortium, May 1 2019, In : Nature genetics. 51, 5, p. 793-803 11 p.

Research output: Contribution to journalArticle

90 Scopus citations

Genome-wide association study identifies loci associated with liability to alcohol and drug dependence that is associated with variability in reward-related ventral striatum activity in African- and European-Americans

Wetherill, L., Lai, D., Johnson, E. C., Anokhin, A., Bauer, L., Bucholz, K. K., Dick, D. M., Hariri, A. R., Hesselbrock, V., Kamarajan, C., Kramer, J., Kuperman, S., Meyers, J. L., Nurnberger, J. I., Schuckit, M., Scott, D. M., Taylor, R. E., Tischfield, J., Porjesz, B., Goate, A. M. & 4 others, Edenberg, H. J., Foroud, T., Bogdan, R. & Agrawal, A., Jul 2019, In : Genes, Brain and Behavior. 18, 6, e12580.

Research output: Contribution to journalArticle

1 Scopus citations

Global gene expression of histologically normal primary skin cells from BCNS subjects reveals "single-hit" effects that are influenced by rapamycin

Phatak, A., Athar, M., Crowell, J. A., Leffel, D., Herbert, B-S., Bale, A. E. & Kopelovich, L., Feb 1 2019, In : Oncotarget. 10, 14, p. 1360-1387 28 p.

Research output: Contribution to journalArticle

2 Scopus citations

Hypusine biosynthesis in β cells links polyamine metabolism to facultative cellular proliferation to maintain glucose homeostasis

Levasseur, E. M., Yamada, K., Piñeros, A. R., Wu, W., Syed, F., Orr, K. S., Anderson-Baucum, E., Mastracci, T. L., Maier, B., Mosley, A. L., Liu, Y., Bernal-Mizrachi, E., Alonso, L. C., Scott, D., Garcia-Ocaña, A., Tersey, S. A. & Mirmira, R. G., Dec 3 2019, In : Science Signaling. 12, 610, eaax0715.

Research output: Contribution to journalArticle

1 Scopus citations

Increased FGF23 protects against detrimental cardio-renal consequences during elevated blood phosphate in CKD

Clinkenbeard, E. L., Noonan, M. L., Thomas, J. C., Ni, P., Hum, J. M., Aref, M., Swallow, E. A., Moe, S. M., Allen, M. R. & White, K. E., Feb 21 2019, In : JCI Insight. 4, 4

Research output: Contribution to journalArticle

6 Scopus citations

Ind-enabling studies for a clinical trial to genetically program a persistent cancer-targeted immune system

Puig-Saus, C., Parisi, G., Garcia-Diaz, A., Krystofinski, P. E., Sandoval, S., Zhang, R., Champhekar, A. S., McCabe, J., Cheung-Lau, G. C., Truong, N. A., Vega-Crespo, A., Komenan, M. D. S., Pang, J., Macabali, M. H., Saco, J. D., Goodwin, J. L., Bolon, B., Seet, C. S., Montel-Hagen, A., Crooks, G. M. & 17 others, Hollis, R. P., Campo-Fernandez, B., Bischof, D., Cornetta, K., Gschweng, E. H., Adelson, C., Nguyen, A., Yang, L., Witte, O. N., Baltimore, D., Comin-Anduix, B., Kohn, D. B., Wang, X., Cabrera, P., Kaplan-Lefko, P. J., Berent-Maoz, B. & Ribas, A., Feb 1 2019, In : Clinical Cancer Research. 25, 3, p. 1000-1011 12 p.

Research output: Contribution to journalArticle

3 Scopus citations

Individualized atrophy scores predict dementia onset in familial frontotemporal lobar degeneration

ARTFL/LEFFTDS consortium, Jan 1 2019, In : Alzheimer's and Dementia.

Research output: Contribution to journalArticle

Open Access
6 Scopus citations

Integration of molecular features with clinical information for predicting outcomes for neuroblastoma patients

Han, Y., Ye, X., Wang, C., Liu, Y., Zhang, S., Feng, W., Huang, K. & Zhang, J., Aug 23 2019, In : Biology Direct. 14, 1, 16.

Research output: Contribution to journalArticle

Open Access

Integrative analysis based on survival associated co-expression gene modules for predicting Neuroblastoma patients' survival time

Han, Y., Ye, X., Cheng, J., Zhang, S., Feng, W., Han, Z., Zhang, J. & Huang, K., Feb 13 2019, In : Biology Direct. 14, 1, 4.

Research output: Contribution to journalArticle

Open Access
1 Scopus citations

JAK2 regulates mismatch repair protein-mediated epigenetic alterations in response to oxidative damage

Ding, N., Miller, S. A., Savant, S. S. & O'Hagan, H. M., May 2019, In : Environmental and Molecular Mutagenesis. 60, 4, p. 308-319 12 p.

Research output: Contribution to journalArticle

5 Scopus citations

Key inflammatory pathway activations in the MCI stage of Alzheimer’s disease

for the Alzheimer’s Disease Neuroimaging Initiative, Jul 2019, In : Annals of Clinical and Translational Neurology. 6, 7, p. 1248-1262 15 p.

Research output: Contribution to journalArticle

Open Access
4 Scopus citations

LAmbDA: Label ambiguous domain adaptation dataset integration reduces batch effects and improves subtype detection

Johnson, T. S., Wang, T., Huang, Z., Yu, C. Y., Wu, Y., Han, Y., Zhang, Y., Huang, K., Zhang, J. & Berger, B., Nov 1 2019, In : Bioinformatics. 35, 22, p. 4696-4706 11 p.

Research output: Contribution to journalArticle

3 Scopus citations
3 Scopus citations
Open Access
1 Scopus citations