Medical & Molecular Genetics

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2016

ESR1 and PGR polymorphisms are associated with estrogen and progesterone receptor expression in breast tumors

Hertz, D. L., Henry, N. L., Kidwell, K. M., Thomas, D., Goddard, A., Azzouz, F., Speth, K., Li, L., Banerjee, M., Thibert, J. N., Kleer, C. G., Stearns, V., Hayes, D. F., Skaar, T. C. & Rae, J. M., Sep 2016, In : Physiological Genomics. 48, 9, p. 688-698 11 p.

Research output: Contribution to journalArticle

1 Scopus citations
19 Scopus citations

Excessive Osteocytic Fgf23 Secretion Contributes to Pyrophosphate Accumulation and Mineralization Defect in Hyp Mice

Murali, S. K., Andrukhova, O., Clinkenbeard, E. L., White, K. & Erben, R. G., Apr 1 2016, In : PLoS Biology. 14, 4, e1002427.

Research output: Contribution to journalArticle

43 Scopus citations

Extracting drug-enzyme relation from literature as evidence for drug drug interaction

Zhang, Y., Wu, H. Y., Du, J., Xu, J., Wang, J., Tao, C., Li, L. & Xu, H., Mar 7 2016, In : Journal of Biomedical Semantics. 7, 1, 11.

Research output: Contribution to journalArticle

4 Scopus citations

Functional characterization of a panel of high-grade serous ovarian cancer cell lines as representative experimental models of the disease

Haley, J., Tomar, S., Pulliam, N., Xiong, S., Perkins, S. M., Karpf, A. R., Mitra, S., Nephew, K. P. & Mitra, A. K., May 31 2016, In : Oncotarget. 7, 22, p. 32810-32820 11 p.

Research output: Contribution to journalArticle

15 Scopus citations

Garcinol inhibits GCN5-mediated lysine acetyltransferase activity and prevents replication of the parasite Toxoplasma gondii

Jeffers, V., Gao, H., Checkley, L. A., Liu, Y., Ferdig, M. T. & Sullivan, W. J., Apr 2016, In : Antimicrobial Agents and Chemotherapy. 60, 4, p. 2164-2170 7 p.

Research output: Contribution to journalArticle

13 Scopus citations

Gene-by-diet interactions affect serum 1,25-dihydroxyvitamin D levels in male BXD recombinant inbred mice

Fleet, J. C., Replogle, R. A., Reyes-Fernandez, P., Wang, L., Zhang, M., Clinkenbeard, E. L. & White, K. E., Feb 2016, In : Endocrinology. 157, 2, p. 470-481 12 p.

Research output: Contribution to journalArticle

2 Scopus citations
19 Scopus citations

Gene targets of mouse miR-709: Regulation of distinct pools

Surendran, S., Jideonwo, V. N., Merchun, C., Ahn, M., Murray, J., Ryan, J., Dunn, K. W., Kota, J. & Morral, N., Jan 8 2016, In : Scientific reports. 6, 18958.

Research output: Contribution to journalArticle

2 Scopus citations

Genetic architecture of age-related cognitive decline in African Americans

Raj, T., Chibnik, L. B., McCabe, C., Wong, A., Replogle, J. M., Yu, L., Gao, S., Unverzagt, F. W., Stranger, B., Murrell, J., Barnes, L., Hendrie, H. C., Foroud, T., Krichevsky, A., Bennett, D. A., Hall, K. S., Evans, D. A. & De Jager, P. L., Jan 1 2016, In : Neurology: Genetics. 3, 1, e125.

Research output: Contribution to journalArticle

10 Scopus citations

Genetic influences on schizophrenia and subcortical brain volumes: Large-scale proof of concept

Psychosis Endophenotypes International Consortium, Feb 23 2016, In : Nature Neuroscience. 19, 3, p. 420-431 12 p.

Research output: Contribution to journalArticle

113 Scopus citations

Genome-wide association study of 40,000 individuals identifies two novel loci associated with bipolar disorder

Hou, L., Bergen, S. E., Akula, N., Song, J., Hultman, C. M., Landén, M., Adli, M., Alda, M., Ardau, R., Arias, B., Aubry, J. M., Backlund, L., Badner, J. A., Barrett, T. B., Bauer, M., Baune, B. T., Bellivier, F., Benabarre, A., Bengesser, S., Berrettini, W. H. & 119 others, Bhattacharjee, A. K., Biernacka, J. M., Birner, A., Bloss, C. S., Brichant-Petitjean, C., Bui, E. T., Byerley, W., Cervantes, P., Chillotti, C., Cichon, S., Colom, F., Coryell, W., Craig, D. W., Cruceanu, C., Czerski, P. M., Davis, T., Dayer, A., Degenhardt, F., Del Zompo, M., DePaulo, J. R., Edenberg, H. J., Étain, B., Falkai, P., Foroud, T., Forstner, A. J., Frisén, L., Frye, M. A., Fullerton, J. M., Gard, S., Garnham, J. S., Gershon, E. S., Goes, F. S., Greenwood, T. A., Grigoroiu-Serbanescu, M., Hauser, J., Heilbronner, U., Heilmann-Heimbach, S., Herms, S., Hipolito, M., Hitturlingappa, S., Hoffmann, P., Hofmann, A., Jamain, S., Jiménez, E., Kahn, J. P., Kassem, L., Kelsoe, J. R., Kittel-Schneider, S., Kliwicki, S., Koller, D. L., König, B., Lackner, N., Laje, G., Lang, M., Lavebratt, C., Lawson, W. B., Leboyer, M., Leckband, S. G., Liu, C., Maaser, A., Mahon, P. B., Maier, W., Maj, M., Manchia, M., Martinsson, L., McCarthy, M. J., McElroy, S. L., McInnis, M. G., McKinney, R., Mitchell, P. B., Mitjans, M., Mondimore, F. M., Monteleone, P., Mühleisen, T. W., Nievergelt, C. M., Nöthen, M. M., Novák, T., Nurnberger, J. I., Nwulia, E. A., Ösby, U., Pfennig, A., Potash, J. B., Propping, P., Reif, A., Reininghaus, E., Rice, J., Rietschel, M., Rouleau, G. A., Rybakowski, J. K., Schalling, M., Scheftner, W. A., Schofield, P. R., Schork, N. J., Schulze, T. G., Schumacher, J., Schweizer, B. W., Severino, G., Shekhtman, T., Shilling, P. D., Simhandl, C., Slaney, C. M., Smith, E. N., Squassina, A., Stamm, T., Stopkova, P., Streit, F., Strohmaier, J., Szelinger, S., Tighe, S. K., Tortorella, A., Turecki, G., Vieta, E., Volkert, J., Witt, S. H., Wright, A., Zandi, P. P., Zhang, P., Zollner, S. & McMahon, F. J., Jan 1 2016, In : Human molecular genetics. 25, 15, p. 3383-3394 12 p.

Research output: Contribution to journalArticle

63 Scopus citations

Genome-wide association study of serum iron phenotypes in premenopausal women of European descent

Koller, D. L., Imel, E. A., Lai, D., Padgett, L. R., Acton, D., Gray, A., Peacock, M., Econs, M. J. & Foroud, T., Mar 1 2016, In : Blood Cells, Molecules, and Diseases. 57, p. 50-53 4 p.

Research output: Contribution to journalArticle

2 Scopus citations

Genome-wide linkage analyses of non-Hispanic white families identify novel loci for familial late-onset Alzheimer's disease

Kunkle, B. W., Jaworski, J., Barral, S., Vardarajan, B., Beecham, G. W., Martin, E. R., Cantwell, L. S., Partch, A., Bird, T. D., Raskind, W. H., Destefano, A. L., Carney, R. M., Cuccaro, M., Vance, J. M., Farrer, L. A., Goate, A. M., Foroud, T., Mayeux, R. P., Schellenberg, G. D., Haines, J. L. & 1 others, Pericak-Vance, M. A., Jan 1 2016, In : Alzheimer's and Dementia. 12, 1, p. 2-10 9 p.

Research output: Contribution to journalArticle

10 Scopus citations

Genome-wide polygenic scores for age at onset of alcohol dependence and association with alcohol-related measures

Kapoor, M., Chou, Y. L., Edenberg, H. J., Foroud, T., Martin, N. G., Madden, P. A. F., Wang, J. C., Bertelsen, S., Wetherill, L., Brooks, A., Chan, G., Hesselbrock, V., Kuperman, S., Medland, S. E., Montgomery, G., Tischfield, J., Whitfield, J. B., Bierut, L. J., Heath, A. C., Bucholz, K. K. & 2 others, Goate, A. M. & Agrawal, A., Jan 1 2016, In : Translational psychiatry. 6, 3, e761.

Research output: Contribution to journalArticle

10 Scopus citations

Global and local ancestry in African-Americans: Implications for Alzheimer's disease risk

Alzheimer Disease Genetics Consortium, Mar 1 2016, In : Alzheimer's and Dementia. 12, 3, p. 233-243 11 p.

Research output: Contribution to journalArticle

10 Scopus citations

Haemophilus ducreyi seeks alternative carbon sources and adapts to nutrient stress and anaerobiosis during experimental infection of human volunteers

Gangaiah, D., Zhang, X., Baker, B., Fortney, K. R., Gao, H., Holley, C. L., Munson, R. S., Liu, Y. & Spinola, S. M., May 1 2016, In : Infection and immunity. 84, 5, p. 1514-1525 12 p.

Research output: Contribution to journalArticle

5 Scopus citations

HDQLIFE: development and assessment of health-related quality of life in Huntington disease (HD)

Carlozzi, N. E., Schilling, S. G., Lai, J. S., Paulsen, J. S., Hahn, E. A., Perlmutter, J. S., Ross, C. A., Downing, N. R., Kratz, A. L., McCormack, M. K., Nance, M. A., Quaid, K. A., Stout, J. C., Gershon, R. C., Ready, R. E., Miner, J. A., Barton, S. K., Perlman, S. L., Rao, S. M., Frank, S. & 6 others, Shoulson, I., Marin, H., Geschwind, M. D., Dayalu, P., Goodnight, S. M. & Cella, D., Oct 1 2016, In : Quality of Life Research. 25, 10, p. 2441-2455 15 p.

Research output: Contribution to journalArticle

23 Scopus citations

High Resolution Genomic Scans Reveal Genetic Architecture Controlling Alcohol Preference in Bidirectionally Selected Rat Model

Lo, C. L., Lossie, A. C., Liang, T., Liu, Y., Xuei, X., Lumeng, L., Zhou, F. C. & Muir, W. M., Aug 2016, In : PLoS Genetics. 12, 8, e1006178.

Research output: Contribution to journalArticle

12 Scopus citations

High-throughput cis-regulatory element discovery in the vector mosquito Aedes aegypti

Behura, S. K., Sarro, J., Li, P., Mysore, K., Severson, D. W., Emrich, S. J. & Duman-Scheel, M., May 10 2016, In : BMC genomics. 17, 1, 341.

Research output: Contribution to journalArticle

9 Scopus citations

Hsp90 and PKM2 drive the expression of aromatase in Li-Fraumeni syndrome breast adipose stromal cells

Subbaramaiah, K., Brown, K. A., Zahid, H., Balmus, G., Weiss, R. S., Herbert, B. S. & Dannenberg, A. J., Jul 29 2016, In : Journal of Biological Chemistry. 291, 31, p. 16011-16023 13 p.

Research output: Contribution to journalArticle

5 Scopus citations

Identification of rifampin-regulated functional modules and related microRNAs in human hepatocytes based on the protein interaction network

Li, J., Wang, Y., Wang, L., Dai, X., Cong, W., Feng, W., Xu, C., Deng, Y., Wang, Y., Skaar, T. C., Liang, H. & Liu, Y., Aug 22 2016, In : BMC genomics. 17, 517.

Research output: Contribution to journalArticle

3 Scopus citations

Identification of TMEM230 mutations in familial Parkinson's disease

Deng, H. X., Shi, Y., Yang, Y., Ahmeti, K. B., Miller, N., Huang, C., Cheng, L., Zhai, H., Deng, S., Nuytemans, K., Corbett, N. J., Kim, M. J., Deng, H., Tang, B., Yang, Z., Xu, Y., Chan, P., Huang, B., Gao, X. P., Song, Z. & 14 others, Liu, Z., Fecto, F., Siddique, N., Foroud, T., Jankovic, J., Ghetti, B., Nicholson, D. A., Krainc, D., Melen, O., Vance, J. M., Pericak-Vance, M. A., Ma, Y. C., Rajput, A. H. & Siddique, T., Jul 1 2016, In : Nature genetics. 48, 7, p. 733-739 7 p.

Research output: Contribution to journalArticle

90 Scopus citations

Improving alignment accuracy on homopolymer regions for semiconductor-based sequencing technologies

Feng, W., Zhao, S., Xue, D., Song, F., Li, Z., Chen, D., He, B., Hao, Y., Wang, Y. & Liu, Y., Aug 22 2016, In : BMC genomics. 17, 521.

Research output: Contribution to journalArticle

7 Scopus citations

Inflammatory profile in LRRK2-associated prodromal and clinical PD

Brockmann, K., Apel, A., Schulte, C., Schneiderhan-Marra, N., Pont-Sunyer, C., Vilas, D., Ruiz-Martinez, J., Langkamp, M., Corvol, J. C., Cormier, F., Knorpp, T., Joos, T. O., Gasser, T., Schüle, B., Aasly, J. O., Foroud, T., Marti-Masso, J. F., Brice, A., Tolosa, E., Marras, C. & 2 others, Berg, D. & Maetzler, W., May 24 2016, In : Journal of Neuroinflammation. 13, 1, 122.

Research output: Contribution to journalArticle

17 Scopus citations

Integration of bioinformatics and imaging informatics for identifying rare PSEN1 variants in Alzheimer's disease

Nho, K., Horgusluoglu, E., Kim, S., Risacher, S. L., Kim, D., Foroud, T., Aisen, P. S., Petersen, R. C., Jack, C. R., Shaw, L. M., Trojanowski, J. Q., Weiner, M. W., Green, R. C., Toga, A. W. & Saykin, A. J., Aug 12 2016, In : BMC Medical Genomics. 9, 30.

Research output: Contribution to journalArticle

9 Scopus citations

Intelligent biology and medicine in 2015: Advancing interdisciplinary education, collaboration, and data science

Huang, K., Liu, Y., Huang, Y., Li, L., Cooper, L., Ruan, J. & Zhao, Z., Aug 22 2016, In : BMC genomics. 17, 524.

Research output: Contribution to journalArticle

7 Scopus citations

Intragenic CFTR Duplication and 5T/12TG Variant in a Patient with Non-Classic Cystic Fibrosis

Celestino-Soper, P. B. S., Simpson, E., Tumbleson Brink, D., Lynnes, T. C., Dlouhy, S., Vatta, M., Yeley, J., Brown, C. & Bai, S., Dec 20 2016, In : Scientific reports. 6, 38776.

Research output: Contribution to journalArticle

Leveraging syntactic and semantic graph kernels to extract pharmacokinetic drug drug interactions from biomedical literature

Zhang, Y., Wu, H. Y., Xu, J., Wang, J., Soysal, E., Li, L. & Xu, H., Aug 26 2016, In : BMC Systems Biology. 10, 67.

Research output: Contribution to journalArticle

10 Scopus citations

Lipopolysaccharide treatment induces genome-wide pre-mRNA splicing pattern changes in mouse bone marrow stromal stem cells

Zhou, A., Li, M., He, B., Feng, W., Huang, F., Xu, B., Dunker, A. K., Balch, C., Li, B., Liu, Y. & Wang, Y., Aug 22 2016, In : BMC genomics. 17, 509.

Research output: Contribution to journalArticle

3 Scopus citations

Mismatch repair proteins recruit DNA methyltransferase 1 to sites of oxidative DNA damage

Ding, N., Bonham, E. M., Hannon, B. E., Amick, T. R., Baylin, S. B. & O'Hagan, H. M., Jun 1 2016, In : Journal of Molecular Cell Biology. 8, 3, p. 244-254 11 p.

Research output: Contribution to journalArticle

26 Scopus citations

Molecular diagnosis of myotonic dystrophy

Chakraborty, S., Vatta, M., Bachinski, L. L., Krahe, R., Dlouhy, S. & Bai, S., 2016, In : Current Protocols in Human Genetics. 2016, p. 9.29.1-9.29.19

Research output: Contribution to journalArticle

3 Scopus citations

New measures to capture end of life concerns in Huntington disease: Meaning and Purpose and Concern with Death and Dying from HDQLIFE (a patient-reported outcomes measurement system)

Carlozzi, N. E., Downing, N. R., McCormack, M. K., Schilling, S. G., Perlmutter, J. S., Hahn, E. A., Lai, J. S., Frank, S., Quaid, K. A., Paulsen, J. S., Cella, D., Goodnight, S. M., Miner, J. A. & Nance, M. A., Oct 1 2016, In : Quality of Life Research. 25, 10, p. 2403-2415 13 p.

Research output: Contribution to journalArticle

18 Scopus citations

NF-κB-HOTAIR axis links DNA damage response, chemoresistance and cellular senescence in ovarian cancer

Özeş, A. R., Miller, D. F., Özeş, O. N., Fang, F., Liu, Y., Matei, D., Huang, T. & Nephew, K. P., Oct 13 2016, In : Oncogene. 35, 41, p. 5350-5361 12 p.

Research output: Contribution to journalArticle

118 Scopus citations

NIPT and Informed Consent: an Assessment of Patient Understanding of a Negative NIPT Result

Piechan, J. L., Hines, K. A., Koller, D. L., Stone, K., Quaid, K., Torres-Martinez, W., Wilson Mathews, D., Foroud, T. & Cook, L., Apr 1 2016, (Accepted/In press) In : Journal of Genetic Counseling. p. 1-11 11 p.

Research output: Contribution to journalArticle

20 Scopus citations

Novel genetic loci underlying human intracranial volume identified through genome-wide association

Adams, H. H. H., Hibar, D. P., Chouraki, V., Stein, J. L., Nyquist, P. A., Rentería, M. E., Trompet, S., Arias-Vasquez, A., Seshadri, S., Desrivières, S., Beecham, A. H., Jahanshad, N., Wittfeld, K., Van Der Lee, S. J., Abramovic, L., Alhusaini, S., Amin, N., Andersson, M., Arfanakis, K., Aribisala, B. S. & 322 others, Armstrong, N. J., Athanasiu, L., Axelsson, T., Beiser, A., Bernard, M., Bis, J. C., Blanken, L. M. E., Blanton, S. H., Bohlken, M. M., Boks, M. P., Bralten, J., Brickman, A. M., Carmichael, O., Chakravarty, M. M., Chauhan, G., Chen, Q., Ching, C. R. K., Cuellar-Partida, G., Braber, A. D., Doan, N. T., Ehrlich, S., Filippi, I., Ge, T., Giddaluru, S., Goldman, A. L., Gottesman, R. F., Greven, C. U., Grimm, O., Griswold, M. E., Guadalupe, T., Hass, J., Haukvik, U. K., Hilal, S., Hofer, E., Hoehn, D., Holmes, A. J., Hoogman, M., Janowitz, D., Jia, T., Kasperaviciute, D., Kim, S., Klein, M., Kraemer, B., Lee, P. H., Liao, J., Liewald, D. C. M., Lopez, L. M., Luciano, M., Macare, C., Marquand, A., Matarin, M., Mather, K. A., Mattheisen, M., Mazoyer, B., McKay, D. R., McWhirter, R., Milaneschi, Y., Mirza-Schreiber, N., Muetzel, R. L., Maniega, S. M., Nho, K., Nugent, A. C., Loohuis, L. M. O., Oosterlaan, J., Papmeyer, M., Pappa, I., Pirpamer, L., Pudas, S., Pütz, B., Rajan, K. B., Ramasamy, A., Richards, J. S., Risacher, S. L., Roiz-Santiañez, R., Rommelse, N., Rose, E. J., Royle, N. A., Rundek, T., Sämann, P. G., Satizabal, C. L., Schmaal, L., Schork, A. J., Shen, L., Shin, J., Shumskaya, E., Smith, A. V., Sprooten, E., Strike, L. T., Teumer, A., Thomson, R., Tordesillas-Gutierrez, D., Toro, R., Trabzuni, D., Vaidya, D., Van Der Grond, J., Van Der Meer, D., Van Donkelaar, M. M. J., Van Eijk, K. R., Van Erp, T. G. M., Van Rooij, D., Walton, E., Westlye, L. T., Whelan, C. D., Windham, B. G., Winkler, A. M., Woldehawariat, G., Wolf, C., Wolfers, T., Xu, B., Yanek, L. R., Yang, J., Zijdenbos, A., Zwiers, M. P., Agartz, I., Aggarwal, N. T., Almasy, L., Ames, D., Amouyel, P., Andreassen, O. A., Arepalli, S., Assareh, A. A., Barral, S., Bastin, M. E., Becker, D. M., Becker, J. T., Bennett, D. A., Blangero, J., Van Bokhoven, H., Boomsma, D. I., Brodaty, H., Brouwer, R. M., Brunner, H. G., Buckner, R. L., Buitelaar, J. K., Bulayeva, K. B., Cahn, W., Calhoun, V. D., Cannon, D. M., Cavalleri, G. L., Chen, C., Cheng, C. Y., Cichon, S., Cookson, M. R., Corvin, A., Crespo-Facorro, B., Curran, J. E., Czisch, M., Dale, A. M., Davies, G. E., De Geus, E. J. C., De Jager, P. L., De Zubicaray, G. I., Delanty, N., Depondt, C., Destefano, A. L., Dillman, A., Djurovic, S., Donohoe, G., Drevets, W. C., Duggirala, R., Dyer, T. D., Erk, S., Espeseth, T., Evans, D. A., Fedko, I. O., Fernández, G., Ferrucci, L., Fisher, S. E., Fleischman, D. A., Ford, I., Foroud, T., Fox, P. T., Francks, C., Fukunaga, M., Gibbs, J. R., Glahn, D. C., Gollub, R. L., Göring, H. H. H., Grabe, H. J., Green, R. C., Gruber, O., Gudnason, V., Guelfi, S., Hansell, N. K., Hardy, J., Hartman, C. A., Hashimoto, R., Hegenscheid, K., Heinz, A., Le Hellard, S., Hernandez, D. G., Heslenfeld, D. J., Ho, B. C., Hoekstra, P. J., Hoffmann, W., Hofman, A., Holsboer, F., Homuth, G., Hosten, N., Hottenga, J. J., Pol, H. E. H., Ikeda, M., Ikram, M. K., Jack, C. R., Jenkinson, M., Johnson, R., Jönsson, E. G., Jukema, J. W., Kahn, R. S., Kanai, R., Kloszewska, I., Knopman, D. S., Kochunov, P., Kwok, J. B., Lawrie, S. M., Lemaître, H., Liu, X., Longo, D. L., Longstreth, W. T., Lopez, O. L., Lovestone, S., Martinez, O., Martinot, J. L., Mattay, V. S., McDonald, C., McIntosh, A. M., McMahon, K. L., McMahon, F. J., Mecocci, P., Melle, I., Meyer-Lindenberg, A., Mohnke, S., Montgomery, G. W., Morris, D. W., Mosley, T. H., Mühleisen, T. W., Müller-Myhsok, B., Nalls, M. A., Nauck, M., Nichols, T. E., Niessen, W. J., Nöthen, M. M., Nyberg, L., Ohi, K., Olvera, R. L., Ophoff, R. A., Pandolfo, M., Paus, T., Pausova, Z., Penninx, B. W. J. H., Pike, G. B., Potkin, S. G., Psaty, B. M., Reppermund, S., Rietschel, M., Roffman, J. L., Romanczuk-Seiferth, N., Rotter, J. I., Ryten, M., Sacco, R. L., Sachdev, P. S., Saykin, A., Schmidt, R., Schofield, P. R., Sigurdsson, S., Simmons, A., Singleton, A., Sisodiya, S. M., Smith, C., Smoller, J. W., Soininen, H., Srikanth, V., Steen, V. M., Stott, D. J., Sussmann, J. E., Thalamuthu, A., Tiemeier, H., Toga, A. W., Traynor, B. J., Troncoso, J., Turner, J. A., Tzourio, C., Uitterlinden, A. G., Hernández, M. C. V., Van Der Brug, M., Van Der Lugt, A., Van Der Wee, N. J. A., Van Duijn, C. M., Van Haren, N. E. M., Van't Ent, D., Van Tol, M. J., Vardarajan, B. N., Veltman, D. J., Vernooij, M. W., Völzke, H., Walter, H., Wardlaw, J. M., Wassink, T. H., Weale, M. E., Weinberger, D. R., Weiner, M. W., Wen, W., Westman, E., White, T., Wong, T. Y., Wright, C. B., Zielke, H. R., Zonderman, A. B., Deary, I. J., Decarli, C., Schmidt, H., Martin, N. G., De Craen, A. J. M., Wright, M. J., Launer, L. J., Schumann, G., Fornage, M., Franke, B., Debette, S., Medland, S. E., Ikram, M. A. & Thompson, P. M., Dec 1 2016, In : Nature Neuroscience. 19, 12, p. 1569-1582 14 p.

Research output: Contribution to journalArticle

82 Scopus citations

Novel role of miR-29a in pancreatic cancer autophagy and its therapeutic potential

Kwon, J. J., Willy, J. A., Quirin, K. A., Wek, R. C., Korc, M., Yin, X. M. & Kota, J., Jan 1 2016, In : Oncotarget. 7, 44, p. 71635-71650 16 p.

Research output: Contribution to journalArticle

26 Scopus citations

Phenotypic and Genotypic Characterization and Treatment of a Cohort With Familial Tumoral Calcinosis/Hyperostosis-Hyperphosphatemia Syndrome

Ramnitz, M. S., Gourh, P., Goldbach-Mansky, R., Wodajo, F., Ichikawa, S., Econs, M. J., White, K. E., Molinolo, A., Chen, M. Y., Heller, T., Del Rivero, J., Seo-Mayer, P., Arabshahi, B., Jackson, M. B., Hatab, S., McCarthy, E., Guthrie, L. C., Brillante, B. A., Gafni, R. I. & Collins, M. T., Oct 1 2016, In : Journal of Bone and Mineral Research. 31, 10, p. 1845-1854 10 p.

Research output: Contribution to journalArticle

30 Scopus citations

Prevalence of maternal cell contamination in amniotic fluid samples

Weida, J., Patil, A. S., Schubert, F., Vance, G., Drendel, H., Reese, A., Dlouhy, S., Bai, S. & Lee, M. J., Oct 12 2016, (Accepted/In press) In : Journal of Maternal-Fetal and Neonatal Medicine. p. 1-5 5 p.

Research output: Contribution to journalArticle

7 Scopus citations

PSRna: Prediction of small RNA secondary structures based on reverse complementary folding method

Li, J., Xu, C., Wang, L., Liang, H., Feng, W., Cai, Z., Wang, Y., Cong, W. & Liu, Y., 2016, (Accepted/In press) In : Journal of Bioinformatics and Computational Biology.

Research output: Contribution to journalArticle

Redeployment of a conserved gene regulatory network during Aedes aegypti development

Suryamohan, K., Hanson, C., Andrews, E., Sinha, S., Scheel, M. D. & Halfon, M. S., Aug 15 2016, In : Developmental Biology. 416, 2, p. 402-413 12 p.

Research output: Contribution to journalArticle

8 Scopus citations

Reduction of Murine Colon Tumorigenesis Driven by Enterotoxigenic Bacteroides fragilis Using Cefoxitin Treatment

Destefano Shields, C. E., Van Meerbeke, S. W., Housseau, F., Wang, H., Huso, D. L., Casero, R. A., O'Hagan, H. M. & Sears, C. L., Jul 1 2016, In : Journal of Infectious Diseases. 214, 1, p. 122-129 8 p.

Research output: Contribution to journalArticle

30 Scopus citations

Rifampin enhances cytochrome P450 (CYP) 2B6-mediated efavirenz 8-hydroxylation in healthy volunteers

Cho, D. Y., Shen, J. H. Q., Lemler, S. M., Skaar, T. C., Li, L., Blievernicht, J., Zanger, U. M., Kim, K. B., Shin, J. G., Flockhart, D. A. & Desta, Z., Apr 2016, In : Drug Metabolism and Pharmacokinetics. 31, 2, p. 107-116 10 p.

Research output: Contribution to journalArticle

6 Scopus citations

Rifampin regulation of drug transporters gene expression and the association of microRNAs in human hepatocytes

Benson, E., Eadon, M., Desta, Z., Liu, Y., Lin, H., Burgess, K. S., Segar, M. W., Gaedigk, A. & Skaar, T., Apr 26 2016, In : Frontiers in Pharmacology. 7, APR, 111.

Research output: Contribution to journalArticle

20 Scopus citations

Robust differentiation of mRNA-reprogrammed human induced pluripotent stem cells toward a retinal lineage

Sridhar, A., Ohlemacher, S. K., Langer, K. B. & Meyer, J. S., Jan 1 2016, In : Stem Cells Translational Medicine. 5, 4, p. 417-426 10 p.

Research output: Contribution to journalArticle

Open Access
20 Scopus citations

Selective suppression of the α isoform of p38 MAPK rescues late-stage tau pathology

Maphis, N., Jiang, S., Xu, G., Kokiko-Cochran, O. N., Roy, S. M., Van Eldik, L. J., Watterson, D. M., Lamb, B. T. & Bhaskar, K., Dec 15 2016, In : Alzheimer's Research and Therapy. 8, 1, p. 1-15 15 p.

Research output: Contribution to journalArticle

30 Scopus citations

Shared genetic contribution to ischemic stroke and Alzheimer's disease

Traylor, M., Adib-Samii, P., Harold, D., Dichgans, M., Williams, J., Lewis, C. M., Markus, H. S., Fornage, M., Holliday, E. G., Sharma, P., Bis, J. C., Psaty, B. M., Seshadri, S., Nalls, M. A., Devan, W. J., Boncoraglio, G., Malik, R., Mitchell, B. D., Kittner, S. J., Ikram, M. A. & 188 others, Clarke, R., Rosand, J., Meschia, J. F., Sudlow, C., Rothwell, P. M., Levi, C., Bevan, S., Kilarski, L. L., Walters, M., Thijs, V., Slowik, A., Lindgren, A., De Bakker, P. I. W., Lambert, J. C., Ibrahim-Verbaas, C. A., Naj, A. C., Sims, R., Bellenguez, C., Jun, G., Destefano, A. L., Beecham, G. W., Grenier-Boley, B., Russo, G., Thornton-Wells, T. A., Jones, N., Smith, A. V., Chouraki, V., Thomas, C., Zelenika, D., Vardarajan, B. N., Kamatani, Y., Lin, C. F., Gerrish, A., Schmidt, H., Kunkle, B., Dunstan, M. L., Ruiz, A., Bihoreau, M. T., Choi, S. H., Reitz, C., Pasquier, F., Hollingworth, P., Ramirez, A., Hanon, O., Fitzpatrick, A. L., Buxbaum, J. D., Campion, D., Crane, P. K., Baldwin, C., Becker, T., Gudnason, V., Cruchaga, C., Craig, D., Amin, N., Berr, C., Lopez, O. L., De Jager, P. L., Deramecourt, V., Johnston, J. A., Evans, D., Lovestone, S., Letenneur, L., Morón, F. J., Rubinsztein, D. C., Eiriksdottir, G., Sleegers, K., Goate, A. M., Fiçvet, N., Huentelman, M. J., Gill, M., Brown, K., Kamboh, M. I., Keller, L., Barberger-Gateau, P., McGuinness, B., Larson, E. B., Green, R., Myers, A. J., Dufouil, C., Todd, S., Wallon, D., Love, S., Rogaeva, E., Gallacher, J., St George-Hyslop, P., Clarimon, J., Lleo, A., Bayer, A., Tsuang, D. W., Yu, L., Tsolaki, M., Bossù, P., Spalletta, G., Proitsi, P., Collinge, J., Sorbi, S., Sanchez-Garcia, F., Fox, N. C., Hardy, J., Deniz Naranjo, M. C., Bosco, P., Brayne, C., Galimberti, D., Mancuso, M., Matthews, F., Moebus, S., Mecocci, P., Del Zompo, M., Maier, W., Hampel, H., Pilotto, A., Bullido, M., Panza, F., Caffarra, P., Nacmias, B., Gilbert, J. R., Mayhaus, M., Lannfelt, L., Hakonarson, H., Pichler, S., Carrasquillo, M. M., Ingelsson, M., Beekly, D., Alvarez, V., Zou, F., Valladares, O., Younkin, S. G., Coto, E., Hamilton-Nelson, K. L., Gu, W., Razquin, C., Pastor, P., Mateo, I., Owen, M. J., Faber, K. M., Jonsson, P. V., Combarros, O., O'Donovan, M. C., Cantwell, L. B., Soininen, H., Blacker, D., Mead, S., Mosley, T. H., Bennett, D. A., Harris, T. B., Fratiglioni, L., Holmes, C., De Bruijn, R. F. A. G., Passmore, P., Montine, T. J., Bettens, K., Rotter, J. I., Brice, A., Morgan, K., Foroud, T. M., Kukull, W. A., Hannequin, D., Powell, J. F., Nalls, M. A., Ritchie, K., Lunetta, K. L., Kauwe, J. S. K., Boerwinkle, E., Riemenschneider, M., Boada, M., Hiltunen, M., Martin, E. R., Schmidt, R., Rujescu, D., Wang, L. S., Dartigues, J. F., Mayeux, R., Tzourio, C., Hofman, A., Nöthen, M. M., Graff, C., Jones, L., Haines, J. L., Holmans, P. A., Lathrop, M., Pericak-Vance, M. A., Launer, L. J., Farrer, L. A., Van Duijn, C. M., Van Broeckhoven, C., Moskvina, V., Schellenberg, G. D. & Amouyel, P., May 1 2016, In : Annals of neurology. 79, 5, p. 739-747 9 p.

Research output: Contribution to journalArticle

26 Scopus citations

Shared genetic risk factors of intracranial, abdominal, and thoracic aneurysms

Aneurysm Consortium, Vascular Research Consortium of New Zealand, Jul 2016, In : Journal of the American Heart Association. 5, 7, e002603.

Research output: Contribution to journalArticle

17 Scopus citations

Statistical modeling for sensitive detection of low-frequency single nucleotide variants

Hao, Y., Zhang, P., Xuei, X., Nakshatri, H., Edenberg, H. J., Li, L. & Liu, Y., Aug 22 2016, In : BMC genomics. 17, 514.

Research output: Contribution to journalArticle

3 Scopus citations

Stepwise Differentiation of Retinal Ganglion Cells from Human Pluripotent Stem Cells Enables Analysis of Glaucomatous Neurodegeneration

Ohlemacher, S. K., Sridhar, A., Xiao, Y., Hochstetler, A. E., Sarfarazi, M., Cummins, T. R. & Meyer, J. S., Jun 1 2016, In : STEM CELLS. 34, 6, p. 1553-1562 10 p.

Research output: Contribution to journalArticle

49 Scopus citations