Pharmacology & Toxicology

Publications 1971 2020

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1971
86 Citations (Scopus)

Control of gene expression in carbohydrate, pyrimidine and DNA metabolism

Weber, G., Queener, S. & Ferdinandus, J. A., 1971, In : Advances in Enzyme Regulation. 9, C, p. 63-95 33 p.

Research output: Contribution to journalArticle

Metabolism
Gene expression
Carbohydrates
Gene Expression
Liver
72 Citations (Scopus)

Dihydrouracil dehydrogenase activity in normal, differentiating and regnerating liver and in hepatomas.

Queener, S., Morris, H. P. & Weber, G., Jul 1971, In : Cancer Research. 31, 7, p. 1004-1009 6 p.

Research output: Contribution to journalArticle

Neoplasm Transplantation
Dihydrouracil Dehydrogenase (NAD+)
Experimental Neoplasms
Liver Regeneration
Thymine
1972
39 Citations (Scopus)

Imbalance in ornithine metabolism in hepatomas of different growth rates as expressed in behavior of L-ornithine carbamyl transferase activity.

Weber, G., Queener, S. & Morris, H. P., Sep 1972, In : Cancer Research. 32, 9, p. 1933-1940 8 p.

Research output: Contribution to journalArticle

Experimental Neoplasms
Ornithine Carbamoyltransferase
Inbred Strains Rats
Liver Regeneration
Ornithine
14 Citations (Scopus)

Metabolic Imbalance in Carbohydrate, Pyrimidine and Ornithine Utilization

Weber, G., Ferdinandus, J. A., Queener, S., Dunaway, G. A. & Trailan, L. J. P., 1972, In : Advances in Enzyme Regulation. 10, C, p. 39-62 24 p.

Research output: Contribution to journalArticle

Ornithine
Medical problems
Starvation
Carbohydrates
Metabolism
1974
17 Citations (Scopus)

Stimulation of calcitonin synthesis and release in vitro by calcium and dibutyryl cyclic AMP

Bell, N. H. & Queener, S., 1974, In : Nature. 248, 5446, p. 343-344 2 p.

Research output: Contribution to journalArticle

Gastrointestinal Hormones
Intestinal Absorption
Gastrins
Calcitonin
Adenylyl Cyclases
1975
20 Citations (Scopus)

Calcitonin: A general survey

Queener, S. & Bell, N. H., 1975, In : Metabolism: Clinical and Experimental. 24, 4, p. 555-567 13 p.

Research output: Contribution to journalArticle

Calcitonin
Hormones
Surveys and Questionnaires

On the lipolytic action of parathyroid hormone (PTH) in man

Sinha, T. K., Thajchayapong, P. & Queener, S., 1975, In : Clinical Research. 23, 3

Research output: Contribution to journalArticle

Parathyroid Hormone

On the lipolytic action of parathyroid hormone in man

Sinha, T. K., Thajchayapong, P. & Queener, S., 1975, In : Clinical Research. 23, 1

Research output: Contribution to journalArticle

Parathyroid Hormone
1976
4 Citations (Scopus)

A radioimmunoassay for serum calcitonin in the rat

Bell, N. H. & Queener, S., 1976, In : Proceedings of the Society for Experimental Biology and Medicine. 152, 4, p. 516-519 4 p.

Research output: Contribution to journalArticle

Calcitonin
Radioimmunoassay
Rats
Serum
Assays

Clinical implications of abnormalities in the metabolism of vitamin D

Bell, N. H. & Queener, S., 1976, In : Journal of Chronic Diseases. 29, 12, p. 743-746 4 p.

Research output: Contribution to journalArticle

Infant, Premature, Diseases
Pseudohypoparathyroidism
Hydroxycholecalciferols
Biliary Liver Cirrhosis
Hypocalcemia
3 Citations (Scopus)

Demonstration that cyclic adenosine 3',5' monophosphate mediates the lipolytic action of parathyroid hormone

Thajchayapong, P., Queener, S., McClintock, R., Allen, D. O. & Bell, N. H., 1976, In : Hormone and Metabolic Research. 8, 3, p. 190-195 6 p.

Research output: Contribution to journalArticle

Parathyroid Hormone
Cyclic AMP
Lipolysis
Demonstrations
Hormones
31 Citations (Scopus)

On the lipolytic action of parathyroid hormone in man

Sinha, T. K., Thajchayapong, P., Queener, S., Allen, D. O. & Bell, N. H., 1976, In : Metabolism: Clinical and Experimental. 25, 3, p. 251-260 10 p.

Research output: Contribution to journalArticle

Lipolysis
Parathyroid Hormone
Pseudohypoparathyroidism
Adenosine
Fats
3 Citations (Scopus)

Treatment of experimental vitamin D3 intoxication in the rat with cholestyramine

Queener, S. & Bell, N. H., 1976, In : Clinical Research. 24, 4

Research output: Contribution to journalArticle

Cholestyramine Resin
Vitamins
1977
12 Citations (Scopus)

Effects of acetazolamide on the renal excretion of phosphate in hypoparathyroidism and pseudohypoparathyroidism

Sinha, T. K., Allen, D. O., Queener, S. & Bell, N. H., 1977, In : Journal of Laboratory and Clinical Medicine. 89, 6, p. 1188-1197 10 p.

Research output: Contribution to journalArticle

Pseudohypoparathyroidism
Hypoparathyroidism
Acetazolamide
Phosphates
Adenosine
18 Citations (Scopus)

Pentobarbital sleeping time and waking blood levels in spontaneously hypertensive rats

Willis, L. R. & Queener, S. F., 1977, In : Canadian Journal of Physiology and Pharmacology. 55, 5, p. 1205-1207 3 p.

Research output: Contribution to journalArticle

Metabolic Clearance Rate
Inbred SHR Rats
Pentobarbital
Sleep
Hypertension
1978
2 Citations (Scopus)

Analysis of sodium fluoride enhancement of calcitonin stimulation of renal cortical adenylate cyclase

Queener, S., Fleming, J. W. & Bell, N. H., 1978, In : Journal of Biological Chemistry. 253, 24, p. 9033-9040 8 p.

Research output: Contribution to journalArticle

Sodium Fluoride
Calcitonin
Adenylyl Cyclases
Kidney
Enzymes
1980
1 Citation (Scopus)

Cardiac adenylate cyclase: Kinetics of synergistic activation by guanosine-5′-triphosphate (GTP) and glucagon

Fricke, R. F., Queener, S. & Clark, C. M., 1980, In : Journal of Molecular and Cellular Cardiology. 12, 6, p. 595-608 14 p.

Research output: Contribution to journalArticle

Guanosine Triphosphate
Glucagon
Adenylyl Cyclases
Proteins
Adenosine Triphosphate
10 Citations (Scopus)

Comparison of the regulation of calcitonin in serum of old and young Buffalo rats

Queener, S., Bell, N. H., Larson, S. M., Henry, D. P. & Slatopolsky, E., 1980, In : Journal of Endocrinology. 87, 1, p. 73-80 8 p.

Research output: Contribution to journalArticle

Buffaloes
Calcitonin
Serum
Calcium
Pentagastrin
1982

±3H-carazolol binding to rabbit renal cortical membranes

Hollingsead, P. S., Queener, S., Besch, H. R. & Willis, L. R., 1982, In : Clinical Research. 30, 2

Research output: Contribution to journalArticle

Rabbits
Kidney
Membranes
carazolol
1 Citation (Scopus)

Solubilization of hormone-responsive adenylate cyclase from human renal cortex

Hamel, F. G. & Queener, S., Sep 30 1982, In : Biochemical and Biophysical Research Communications. 108, 2, p. 567-575 9 p.

Research output: Contribution to journalArticle

Adenylyl Cyclases
Calcitonin
Hormones
Glucagon
Kidney
1983
33 Citations (Scopus)

Changes in renal phospholipid fatty acids in diabetes mellitus: Correlation with changes in adenylate cyclase activity

Clark, D. L., Hamel, F. G. & Queener, S., Oct 1983, In : Lipids. 18, 10, p. 696-705 10 p.

Research output: Contribution to journalArticle

adenylate cyclase
Medical problems
diabetes mellitus
Adenylyl Cyclases
Cell membranes
6 Citations (Scopus)

Effect of gentamicin treatment on adenylate cyclase and Na+,K+-ATPase activities in renal tissues of rats

Queener, S., Luft, F. C. & Hamel, F. G., 1983, In : Antimicrobial Agents and Chemotherapy. 24, 5, p. 815-818 4 p.

Research output: Contribution to journalArticle

Gentamicins
Adenylyl Cyclases
Kidney
Cell Membrane
Isoproterenol
1984

Renal lipid desaturation in diabetes mellitus

Clark, D. L. & Queener, S., 1984, In : Federation Proceedings. 43, 7

Research output: Contribution to journalArticle

Diabetes Mellitus
Kidney
Lipids
1985
13 Citations (Scopus)

Effects of diabetes mellitus on renal fatty acid activation and desaturation

Clark, D. L. & Queener, S., Dec 15 1985, In : Biochemical Pharmacology. 34, 24, p. 4305-4310 6 p.

Research output: Contribution to journalArticle

Linoleoyl-CoA Desaturase
Stearoyl-CoA Desaturase
Coenzyme A Ligases
Acyl Coenzyme A
Medical problems
1986
12 Citations (Scopus)

Activity of inosine analogs against Pneumocystis carinii in culture

Bartlett, M. S., Marr, J. J., Queener, S., Klein, R. S. & Smith, J. W., 1986, In : Antimicrobial Agents and Chemotherapy. 30, 1, p. 181-183 3 p.

Research output: Contribution to journalArticle

Pneumocystis carinii
Inosine
allopurinol riboside
9-deazainosine
formycin B
24 Citations (Scopus)

Biliary excretion of organic anions in diabetic rats

Watkins, J. B. & Noda, H., 1986, In : Journal of Pharmacology and Experimental Therapeutics. 239, 2, p. 467-473 7 p.

Research output: Contribution to journalArticle

10 Citations (Scopus)

Translocatable estrogen receptors in rat splenocytes

Myers, M. J., Heim, M. C., Hirsch, K. S., Queener, S. & Petersen, B. H., Jul 28 1986, In : Life Sciences. 39, 4, p. 313-320 8 p.

Research output: Contribution to journalArticle

Estrogen Receptors
Rats
Estradiol
Immune system
Immune System
1987
56 Citations (Scopus)

Activity of lipid-soluble inhibitors of dihydrofolate reductase against Pneumocystis carinii in culture and in a rat model of infection

Queener, S., Bartlett, M. S., Jay, M. A., Durkin, M. M. & Smith, J. W., 1987, In : Antimicrobial Agents and Chemotherapy. 31, 9, p. 1323-1327 5 p.

Research output: Contribution to journalArticle

Folic Acid Antagonists
Pneumocystis carinii
Trimetrexate
Lipids
Infection
36 Citations (Scopus)

Alterations in biliary excretory function by streptozotocin-induced diabetes

Watkins, J. B. & Dykstra, T. P., 1987, In : Drug Metabolism and Disposition. 15, 2, p. 177-183 7 p.

Research output: Contribution to journalArticle

Experimental Diabetes Mellitus
Streptozocin
Medical problems
Rats
Phenolsulfonphthalein
5 Citations (Scopus)
Inbred WKY Rats
Streptozocin
Biotransformation
Sprague Dawley Rats
Sulfobromophthalein
18 Citations (Scopus)

Improved rat model for studying Pneumocystis carinii pneumonia

Bartlett, M. S., Queener, S., Jay, M. A., Durkin, M. M. & Smith, J. W., 1987, In : Journal of Clinical Microbiology. 25, 3, p. 480-484 5 p.

Research output: Contribution to journalArticle

Pneumocystis Pneumonia
Pneumocystis Infections
T-Lymphocytes
Immunosuppression
Hydrocortisone
16 Citations (Scopus)

Lithium and haloperidol differentially alter the dynorphin A (1-8) and enkephalin levels in the neurointermediate lobe of rat pituitary

Sivam, S., Smith, D. R., Takeuchi, K. & Hong, J. S., 1987, In : Neuropeptides. 10, 3, p. 291-298 8 p.

Research output: Contribution to journalArticle

dynorphin (1-8)
Enkephalins
Haloperidol
Lithium
Rats
1988
64 Citations (Scopus)

Activity of clindamycin with primaquine against Pneumocystis carinii in vitro and in vivo

Queener, S., Bartlett, M. S., Richardson, J. D., Durkin, M. M., Jay, M. A. & Smith, J. W., 1988, In : Antimicrobial Agents and Chemotherapy. 32, 6, p. 807-813 7 p.

Research output: Contribution to journalArticle

Primaquine
Pneumocystis carinii
Clindamycin
Pneumocystis Infections
Pneumocystis Pneumonia
3 Citations (Scopus)

Hepatic phase II biotransformation in C57Bl/KsJ db/db mice: comparison to that in swiss webster and 129 REJ mice

Watkins, J. B. & klueber, K. M., 1988, In : Comparative Biochemistry and Physiology. Part C: Comparative. 90, 2, p. 417-421 5 p.

Research output: Contribution to journalArticle

129 Strain Mouse
Biotransformation
Liver
Ethacrynic Acid
Dinitrochlorobenzene
35 Citations (Scopus)

Lithium increases dynorphin A(1-8) and prodynorphin mRNA levels in the basal ganglia of rats

Sivam, S., Takeuchi, K., Li, S., Douglass, J., Civelli, O., Calvetta, L., Herbert, E., McGinty, J. F. & Hong, J. S., 1988, In : Molecular Brain Research. 3, 2, p. 155-163 9 p.

Research output: Contribution to journalArticle

dynorphin (1-8)
Basal Ganglia
Lithium
Messenger RNA
Haloperidol
98 Citations (Scopus)

New rat model of Pneumocystis carinii infection

Bartlett, M. S., Fishman, J. A., Queener, S., Durkin, M. M., Jay, M. A. & Smith, J. W., 1988, In : Journal of Clinical Microbiology. 26, 6, p. 1100-1102 3 p.

Research output: Contribution to journalArticle

Pneumocystis Infections
Pneumocystis carinii
Injections
Pneumocystis Pneumonia
Infection
32 Citations (Scopus)

The effect of long-term streptozotocin-induced diabetes on the hepatotoxicity of bromobenzene and carbon tetrachloride and hepatic biotransformation in rats

Watkins, J. B., Sanders, R. A. & Beck, L. V., 1988, In : Toxicology and Applied Pharmacology. 93, 2, p. 329-338 10 p.

Research output: Contribution to journalArticle

Experimental Diabetes Mellitus
Carbon Tetrachloride
Streptozocin
Medical problems
Biotransformation
1989
5 Citations (Scopus)

A culture method allowing production of relatively pure Pneumocystis carinii trophozoites

Durkin, M. M., Bartlett, M. S., Queener, S., Shaw, M. M. & Smith, J. W., 1989, In : Journal of Protozoology. 36, 1

Research output: Contribution to journalArticle

Pneumocystis carinii
Trophozoites
Dextrans
Microspheres
Culture Media
1 Citation (Scopus)

An improved rat model to study efficacy of drugs for treatment or prophylaxis of Pneumocystis carinii pneumonia

Barlett, M. S., Fishman, J. A., Durkin, M. M., Queener, S. & Smith, J. W., 1989, In : Journal of Protozoology. 36, 1

Research output: Contribution to journalArticle

Inbred Strains Rats
Animal Disease Models
Sulfamethoxazole
Drug Evaluation
Trimethoprim
12 Citations (Scopus)

Binary fission of Pneumocystis carinii trophozoites grown in vitro

Richardson, J. D., Queener, S., Bartlett, M. & Smith, J., 1989, In : Journal of Protozoology. 36, 1

Research output: Contribution to journalArticle

Pneumocystis carinii
Trophozoites
Cell Division
Cacodylic Acid
Osmium Tetroxide
25 Citations (Scopus)

Calcium regulates some, but not all, aspects of light adaptation in rod photoreceptors

Nicol, G. & Bownds, M. D., 1989, In : Journal of General Physiology. 94, 2, p. 233-259 27 p.

Research output: Contribution to journalArticle

Ocular Adaptation
Retinal Rod Photoreceptor Cells
Rhodopsin
Calcimycin
Calcium
6 Citations (Scopus)

Carbon tetrachloride and the sorbitol pathway in the diabetic mouse

Gaynes, B. I. & Watkins, J. B., 1989, In : Comparative Biochemistry and Physiology -- Part B: Biochemistry and. 94, 1, p. 213-217 5 p.

Research output: Contribution to journalArticle

Sorbitol
Carbon Tetrachloride
Fructose
L-Iditol 2-Dehydrogenase
Liver
147 Citations (Scopus)
Dynorphins
Cocaine
Enkephalins
Corpus Striatum
Dopamine
19 Citations (Scopus)
Sorbitol
Fructose
Liver
Lenses
Rats
36 Citations (Scopus)
Self-Injurious Behavior
Dopamine D1 Receptors
Denervation
Substance P
Oxidopamine
13 Citations (Scopus)
Xenobiotics
Anesthetics
Digoxin
Halothane
Acetaminophen
35 Citations (Scopus)

Lithium increases rat striatal beta- and gamma-preprotachykinin messenger RNAs

Sivam, S., Krause, J. E., Takeuchi, K., Li, S., McGinty, J. F. & Hong, J. S., 1989, In : Journal of Pharmacology and Experimental Therapeutics. 248, 3, p. 1297-1301 5 p.

Research output: Contribution to journalArticle

Corpus Striatum
Lithium
Messenger RNA
Substance P
Haloperidol
21 Citations (Scopus)

Skeletal muscle in the diabetic mouse: histochemical and morphometric analysis

Klueber, K. M., Feczko, J. D., Schmidt, G. & Watkins, J. B., 1989, In : Anatomical Record. 225, 1, p. 41-45 5 p.

Research output: Contribution to journalArticle

skeletal muscle
Skeletal Muscle
Muscles
muscles
mice
14 Citations (Scopus)

Tricyclic 2,4-diaminopyrimidines with broad antifolate activity and the ability to inhibit pneumocystis carinii growth in cultured human lung fibroblasts in the presence of leucovorin

Rosowsky, A., Freisheim, J. H., Hynes, J. B., Queener, S., Bartlett, M., Smith, J. W., Lazarus, H. & Modest, E. J., Aug 15 1989, In : Biochemical Pharmacology. 38, 16, p. 2677-2684 8 p.

Research output: Contribution to journalArticle

Quinazolines
Folic Acid Antagonists
Pneumocystis carinii
Leucovorin
Fibroblasts
1990
15 Citations (Scopus)
Substance P
Adenosine
Spinal Cord
Potassium
Morphine