Pharmacology & Toxicology

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The transcription of bradyzoite genes in Toxoplasma gondii is controlled by autonomous promoter elements

Behnke, M. S., Radke, J. B., Smith, A. T., Sullivan, W. J. & White, M. W., Jun 2008, In : Molecular Microbiology. 68, 6, p. 1502-1518 17 p.

Research output: Contribution to journalArticle

72 Scopus citations

The TrkA receptor mediates experimental thermal hyperalgesia produced by nerve growth factor: Modulation by the p75 neurotrophin receptor

Khodorova, A., Nicol, G. D. & Strichartz, G., Jan 6 2017, In : Neuroscience. 340, p. 384-397 14 p.

Research output: Contribution to journalArticle

11 Scopus citations

The unfolded protein response in the protozoan parasite Toxoplasma gondii features translational and transcriptional control

Joyce, B. R., Tampaki, Z., Kim, K., Wek, R. C. & Sullivan, W. J., Jul 2013, In : Eukaryotic Cell. 12, 7, p. 979-989 11 p.

Research output: Contribution to journalArticle

24 Scopus citations

The Xpc gene markedly affects cell survival in mouse bone marrow

Fischer, J. L., Kumar, M. A. S., Day, T. W., Hardy, T. M., Hamilton, S., Besch-Williford, C., Safa, A. R., Pollok, K. E. & Smith, M. L., Jul 2009, In : Mutagenesis. 24, 4, p. 309-316 8 p.

Research output: Contribution to journalArticle

6 Scopus citations

The α1-adrenergic photoaffinity probe [125I]arylazidoprazosin binds to a specific peptide of P-glycoprotein in multidrug-resistant cells

Sapa, A. R., Agresti, M., Tamai, I., Mehta, N. D. & Vahabi, S., Jan 15 1990, In : Biochemical and Biophysical Research Communications. 166, 1, p. 259-266 8 p.

Research output: Contribution to journalArticle

27 Scopus citations

Tight Control of Platelet-derived Growth Factor B/c-sis Expression by Interplay between the 5′-Untranslated Region Sequence and the Major Upstream Promoter

Han, B., Dong, Z. & Zhang, J. T., Nov 21 2003, In : Journal of Biological Chemistry. 278, 47, p. 46983-46993 11 p.

Research output: Contribution to journalArticle

18 Scopus citations

Tissue-Specific Distribution of Differentially Phosphorylated Forms of Cx43

Kadle, R., Zhang, J. T. & Nicholson, B. J., Jan 1991, In : Molecular and cellular biology. 11, 1, p. 363-369 7 p.

Research output: Contribution to journalArticle

Open Access
101 Scopus citations
26 Scopus citations

Topogenesis of cystic fibrosis transmembrane conductance regulator (CFTR): Regulation by the amino terminal transmembrane sequences

Chen, M. & Zhang, J. T., Apr 27 1999, In : Biochemistry. 38, 17, p. 5471-5477 7 p.

Research output: Contribution to journalArticle

21 Scopus citations

Topological determinants of internal transmembrane segments in P- glycoprotein sequences

Zhang, J. T., Chow Hwee Lee, H. L., Duthie, M. & Ling, V., Jan 1 1995, In : Journal of Biological Chemistry. 270, 4, p. 1742-1746 5 p.

Research output: Contribution to journalArticle

Open Access
41 Scopus citations

Topological folding and proteolysis profile of P-glycoprotein in membranes of multidrug-resistant cells: Implications for the drug-transport mechanism

Zhang, M., Wang, G., Shapiro, A. & Zhang, J. T., Sep 25 1996, In : Biochemistry. 35, 30, p. 9728-9736 9 p.

Research output: Contribution to journalArticle

46 Scopus citations

Toxicological effects of gamma-irradiated sewage solids fed as seven percent of diet to sheep for four years

Smith, G. S., Hallford, D. M. & Watkins, J. B., 1985, In : J. ANIM. SCI.. 61, 4, p. 931-941 11 p.

Research output: Contribution to journalArticle

3 Scopus citations

Toxoplasma gondii AP2IX-4 regulates gene expression during bradyzoite development

Huang, S., Holmes, M. J., Radke, J. B., Hong, D. P., Liu, T. K., White, M. W. & Sullivan, W. J., Mar 1 2017, In : mSphere. 2, 2, e00054-17.

Research output: Contribution to journalArticle

17 Scopus citations

Toxoplasma gondii co-opts the unfolded protein response to enhance migration and dissemination of infected host cells

Augusto, L., Martynowicz, J., Amin, P. H., Alakhras, N. S., Kaplan, M. H., Wek, R. C. & Sullivan, W. J., Aug 2020, In : mBio. 11, 4, p. 1-13 13 p., e00915-20.

Research output: Contribution to journalArticle

Open Access

Toxoplasma gondii lysine acetyltransferase GCN5-a functions in the cellular response to alkaline stress and expression of cyst genes

Naguleswaran, A., Elias, E. V., McClintick, J., Edenberg, H. J. & Sullivan, W. J., 2010, In : PLoS pathogens. 6, 12, e1001232.

Research output: Contribution to journalArticle

29 Scopus citations

Toxoplasma gondii-positive human sera recognise intracellular tachyzoites and bradyzoites with diverse patterns of immunoreactivity

Roiko, M. S., LaFavers, K., Leland, D. & Arrizabalaga, G., Mar 2018, In : International Journal for Parasitology. 48, 3-4, p. 225-232 8 p.

Research output: Contribution to journalArticle

2 Scopus citations

Toxoplasma gondii Sis1-like J-domain protein is a cytosolic chaperone associated to HSP90/HSP70 complex

Figueras, M. J., Martin, O. A., Echeverria, P. C., de Miguel, N., Naguleswaran, A., Sullivan, W. J., Corvi, M. M. & Angel, S. O., Apr 1 2012, In : International Journal of Biological Macromolecules. 50, 3, p. 725-733 9 p.

Research output: Contribution to journalArticle

8 Scopus citations

Toxoplasma H2A Variants Reveal Novel Insights into Nucleosome Composition and Functions for this Histone Family

Dalmasso, M. C., Onyango, D. O., Naguleswaran, A., Sullivan, W. J. & Angel, S. O., Sep 11 2009, In : Journal of molecular biology. 392, 1, p. 33-47 15 p.

Research output: Contribution to journalArticle

34 Scopus citations

TRAIL recombinant adenovirus triggers robust apoptosis in multidrug-resistant HL-60/Vinc cells preferentially through death receptor DR5

Wu, C. H., Kao, C. H. & Safa, A. R., Jul 1 2008, In : Human gene therapy. 19, 7, p. 731-743 13 p.

Research output: Contribution to journalArticle

6 Scopus citations

Trails of discovery: Unbreak my heart: A short history of the defibrillator and CPR

Sullivan, W., 2016, In : Dialogues in Cardiovascular Medicine. 21, 3, p. 217-221 5 p.

Research output: Contribution to journalArticle

Transcriptional repression by ApiAP2 factors is central to chronic toxoplasmosis

Radke, J. B., Worth, D., Hong, D., Huang, S., Sullivan, W. J., Wilson, E. H. & White, M. W., May 2018, In : PLoS pathogens. 14, 5, e1007035.

Research output: Contribution to journalArticle

19 Scopus citations

Transduction persists in rod photoreceptors after depletion of intracellular calcium

Nicol, G. D., Benjamin Kaupp, U. & Deric Bownds, M., Feb 1 1987, In : Journal of General Physiology. 89, 2, p. 297-319 23 p.

Research output: Contribution to journalArticle

Open Access
12 Scopus citations

Transfection of rat or mouse neurons by biolistics or electroporation

Dib-Hajj, S. D., Choi, J. S., Macala, L. J., Tyrrell, L., Black, J. A., Cummins, T. R. & Waxman, S. G., Aug 17 2009, In : Nature protocols. 4, 8, p. 1118-1126 9 p.

Research output: Contribution to journalArticle

87 Scopus citations

Translational regulation of RPA2 via internal ribosomal entry site and by eIF3a

Yin, J. Y., Dong, Z. Z., Liu, R. Y., Chen, J., Liu, Z. Q. & Zhang, J. T., Jun 1 2013, In : Carcinogenesis. 34, 6, p. 1224-1231 8 p.

Research output: Contribution to journalArticle

24 Scopus citations

Translation regulation by eukaryotic initiation factor-2 kinases in the development of latent cysts in Toxoplasma gondii

Narasimhan, J., Joyce, B. R., Naguleswaran, A., Smith, A. T., Livingston, M. R., Dixon, S. E., Coppens, I., Wek, R. C. & Sullivan, W. J., Jun 13 2008, In : Journal of Biological Chemistry. 283, 24, p. 16591-16601 11 p.

Research output: Contribution to journalArticle

75 Scopus citations

Translocatable estrogen receptors in rat splenocytes

Myers, M. J., Heim, M. C., Hirsch, K. S., Queener, S. F. & Petersen, B. H., Jul 28 1986, In : Life Sciences. 39, 4, p. 313-320 8 p.

Research output: Contribution to journalArticle

10 Scopus citations

Treatment of experimental vitamin D3 intoxication in the rat with cholestyramine

Queener, S. F. & Bell, N. H., Jan 1 1976, In : Clinical Research. 24, 4, p. 583A

Research output: Contribution to journalArticle

3 Scopus citations

Tricyclic 2,4-diaminopyrimidines with broad antifolate activity and the ability to inhibit pneumocystis carinii growth in cultured human lung fibroblasts in the presence of leucovorin

Rosowsky, A., Freisheim, J. H., Hynes, J. B., Queener, S. F., Bartlett, M., Smith, J. W., Lazarus, H. & Modest, E. J., Aug 15 1989, In : Biochemical Pharmacology. 38, 16, p. 2677-2684 8 p.

Research output: Contribution to journalArticle

14 Scopus citations

Trimethoprim resistance of dihydrofolate reductase variants from clinical isolates of Pneumocystis jirovecii

Queener, S. F., Cody, V., Pace, J., Torkelson, P. & Gangjee, A., Oct 2013, In : Antimicrobial Agents and Chemotherapy. 57, 10, p. 4990-4998 9 p.

Research output: Contribution to journalArticle

25 Scopus citations

TRPA1 receptors mediate environmental irritant-induced meningeal vasodilatation

Kunkler, P. E., Ballard, C. J., Oxford, G. S. & Hurley, J. H., Jan 1 2011, In : Pain. 152, 1, p. 38-44 7 p.

Research output: Contribution to journalArticle

93 Scopus citations

Tumor necrosis factor enhances the capsaicin sensitivity of rat sensory neurons

Nicol, G. D., Lopshire, J. C. & Pafford, C. M., 1997, In : Journal of Neuroscience. 17, 3, p. 975-982 8 p.

Research output: Contribution to journalArticle

Open Access
121 Scopus citations
55 Scopus citations
44 Scopus citations

Twenty-four hour exposure to prostaglandin downregulates prostanoid receptor binding but does not alter PGE2-mediated sensitization of rat sensory neurons

Southall, M. D., Bolyard, L. A. & Vasko, M. R., Apr 27 2002, In : Pain. 96, 3, p. 285-296 12 p.

Research output: Contribution to journalArticle

13 Scopus citations

Two subcellular localizations of eIF3 p170 and its interaction with membrane-bound microfilaments: Implications for alternative functions of p170

Pincheira, R., Chen, Q., Huang, Z. & Zhang, J. T., Jan 1 2001, In : European Journal of Cell Biology. 80, 6, p. 410-418 9 p.

Research output: Contribution to journalArticle

29 Scopus citations

Types of Pneumocystis carinii detected in air samples

Bartlett, M. S., Lu, J. J., Lee, C. H., Durant, P. J., Queener, S. F. & Smith, J. W., 1996, In : Journal of Eukaryotic Microbiology. 43, 5, p. 44S

Research output: Contribution to journalArticle

17 Scopus citations

Typing of Pneumocystis carinii strains that infect humans based on nucleotide sequence variations of internal transcribed spacers of rRNA genes

Lu, J. J., Bartlett, M. S., Shaw, M. M., Queener, S. F., Smith, J. W., Rivera, M. O., Leibowitz, M. J. & Chao Hung Lee, H. L., 1994, In : Journal of clinical microbiology. 32, 12, p. 2904-2912 9 p.

Research output: Contribution to journalArticle

Open Access
104 Scopus citations

Ultraviolet photoalteration of ion channels in voltage-clamped lobster giant axons

Oxford, G. S. & Pooler, J. P., Dec 1 1975, In : The Journal of Membrane Biology. 20, 1, p. 13-30 18 p.

Research output: Contribution to journalArticle

27 Scopus citations

Understanding mechanisms and the role of differentiation in pathogenesis of Toxoplasma gondii - A Review

Sullivan, W. J., Smith, A. T. & Joyce, B. R., Mar 2009, In : Memorias do Instituto Oswaldo Cruz. 104, 2, p. 155-161 7 p.

Research output: Contribution to journalArticle

Open Access
29 Scopus citations

Unusual Voltage-Gated Sodium Currents as Targets for Pain

Barbosa, C. & Cummins, T., 2016, (Accepted/In press) In : Current Topics in Membranes.

Research output: Contribution to journalArticle

4 Scopus citations

Upregulation of the sodium channel Na v β4 subunit and its contributions to mechanical hypersensitivity and neuronal hyperexcitability in a rat model of radicular pain induced by local dorsal root ganglion inflammation

Xie, W., Tan, Z. Y., Barbosa, C., Strong, J. A., Cummins, T. R. & Zhang, J. M., Apr 1 2016, In : Pain. 157, 4, p. 879-891 13 p.

Research output: Contribution to journalArticle

19 Scopus citations
12 Scopus citations

Use of cell-free systems to determine P-glycoprotein transmembrane topology

Zhang, J. T., Jan 1 1998, In : Methods in Enzymology. 292, p. 279-289 11 p.

Research output: Contribution to journalArticle

Use of non-mammalian alternative models for neurotoxicological study

Peterson, R. T., Nass, R., Boyd, W. A., Freedman, J. H., Dong, K. & Narahashi, T., May 2008, In : NeuroToxicology. 29, 3, p. 546-555 10 p.

Research output: Contribution to journalArticle

122 Scopus citations

Validation-based insertional mutagenesis identifies lysine demethylase FBXL11 as a negative regulator of NFκB

Lu, T., Jackson, M. W., Singhi, A. D., Kandel, E. S., Yang, M., Zhang, Y., Gudkov, A. V. & Stark, G. R., Sep 22 2009, In : Proceedings of the National Academy of Sciences of the United States of America. 106, 38, p. 16339-16344 6 p.

Research output: Contribution to journalArticle

59 Scopus citations

Vasodilatation in the rat dorsal hindpaw induced by activation of sensory neurons is reduced by paclitaxel

Gracias, N. G., Cummins, T. R., Kelley, M. R., Basile, D. P., Iqbal, T. & Vasko, M. R., Jan 2011, In : NeuroToxicology. 32, 1, p. 140-149 10 p.

Research output: Contribution to journalArticle

18 Scopus citations

Venipuncture in the medical physiology laboratory

Martin, B. J., Watkins, J. B. & Ramsey, J., 1998, In : American Journal of Physiology. 274, 6 PART 2, p. S62-S67

Research output: Contribution to journalArticle

3 Scopus citations

Vinblastine photoaffinity labeling of a high molecular weight surface membrane glycoprotein specific for multidrug-resistant cells

Safa, A. R., Glover, C. J., Meyers, M. B., Biedler, J. L. & Felsted, R. L., 1986, In : Journal of Biological Chemistry. 261, 14, p. 6137-6140 4 p.

Research output: Contribution to journalArticle

240 Scopus citations

Voltage-clamp and current-clamp recordings from mammalian DRG neurons

Cummins, T. R., Rush, A. M., Estacion, M., Dib-Hajj, S. D. & Waxman, S. G., Aug 17 2009, In : Nature protocols. 4, 8, p. 1103-1112 10 p.

Research output: Contribution to journalArticle

69 Scopus citations

Voltage-dependent ion channels in CAD cells: A catecholaminergic neuronal line that exhibits inducible differentiation

Wang, H. & Oxford, G. S., Dec 27 2000, In : Journal of Neurophysiology. 84, 6, p. 2888-2895 8 p.

Research output: Contribution to journalArticle

26 Scopus citations