Pharmacology & Toxicology

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±3H-carazolol binding to rabbit renal cortical membranes

Hollingsead, P. S., Queener, S. F., Besch, H. R. & Willis, L. R., Jan 1 1982, In : Clinical research. 30, 2, p. 450A

Research output: Contribution to journalArticle

14-3-3σ contributes to radioresistance by regulating DNA repair and cell cycle via PARP1 and CHK2

Chen, Y., Li, Z., Dong, Z., Beebe, J., Yang, K., Fu, L. & Zhang, J. T., Apr 2017, In : Molecular Cancer Research. 15, 4, p. 418-428 11 p.

Research output: Contribution to journalArticle

13 Scopus citations

14-3-3σ regulation of and interaction with YAP1 in acquired gemcitabine resistance via promoting ribonucleotide reductase expression

Qin, L., Dong, Z. & Zhang, J. T., Jan 1 2016, In : Oncotarget. 7, 14, p. 17726-17736 11 p.

Research output: Contribution to journalArticle

3 Scopus citations

2,4-Diamino-5-chloroquinazoline Analogs of Trimetrexate and Piritrexim: Synthesis and Antifolate Activity

Rosowsky, A., Mota, C. E., Wright, J. E. & Queener, S. F., Dec 1 1994, In : Journal of Medicinal Chemistry. 37, 26, p. 4522-4528 7 p.

Research output: Contribution to journalArticle

44 Scopus citations

2,4-Diamino-5-deaza-6-substituted pyrido[2,3-d]pyrimidine antifolates as potent and selective nonclassical inhibitors of dihydrofolate reductases

Gangjee, A., Vasudevan, A., Queener, S. F. & Kisliuk, R. L., Mar 29 1996, In : Journal of Medicinal Chemistry. 39, 7, p. 1438-1446 9 p.

Research output: Contribution to journalArticle

116 Scopus citations
37 Scopus citations
18 Scopus citations
28 Scopus citations

2,4- Diaminopyrido[3,2-d]pyrimidine Inhibitors of Dihydrofolate Reductase from Pneumocystis carinii and Toxoplasma gondii

Rosowsky, A., Forsch, R. A. & Queener, S. F., Jul 1 1995, In : Journal of Medicinal Chemistry. 38, 14, p. 2615-2620 6 p.

Research output: Contribution to journalArticle

35 Scopus citations

2,4-Diaminothieno[2,3-d]pyrimidine Analogues of Trimetrexate and Piritrexim as Potential Inhibitors of Pneumocystis carinii and Toxoplasma gondii Dihydrofolate Reductase

Rosowsky, A., Mota, C. E., Wright, J. E., Freisheim, J. H., Heusner, J. J., McCormack, J. J. & Queener, S. F., Jan 1 1993, In : Journal of Medicinal Chemistry. 36, 21, p. 3103-3112 10 p.

Research output: Contribution to journalArticle

68 Scopus citations

2,4-Diaminothieno[2,3-d]pyrimidine lipophilic antifolates as inhibitors of Pneumocystis carinii and Toxoplasma gondii dihydrofolate reductase

Rosowsky, A., Papoulis, A. T. & Queener, S. F., Nov 11 1997, In : Journal of Medicinal Chemistry. 40, 22, p. 3694-3699 6 p.

Research output: Contribution to journalArticle

42 Scopus citations

2-amino-4-oxo-5-substituted-pyrrolo[2,3-d]pyrimidines as nonclassical antifolate inhibitors of thymidylate synthase

Gangjee, A., Mavandadi, F., Kisliuk, R. L., McGuire, J. J. & Queener, S. F., Nov 26 1996, In : Journal of Medicinal Chemistry. 39, 23, p. 4563-4568 6 p.

Research output: Contribution to journalArticle

43 Scopus citations

3,4-methylenedioxymethamphetamine increases excitability in the dentate gyrus: Role of 5HT2A receptor-induced PGE2 signaling

Collins, S. A., Huff, C., Chiaia, N., Gudelsky, G. A. & Yamamoto, B. K., Mar 1 2016, In : Journal of Neurochemistry. 136, 5, p. 1074-1084 11 p.

Research output: Contribution to journalArticle

3 Scopus citations

4-(4-Chloro-2-methylphenoxy)-N-hydroxybutanamide (CMH) targets mRNA of the c-FLIP variants and induces apoptosis in MCF-7 human breast cancer cells

Bijangi-Vishehsaraei, K., Saadatzadeh, M. R., Huang, S., Murphy, M. P. & Safa, A. R., Sep 1 2010, In : Molecular and Cellular Biochemistry. 342, 1-2, p. 133-142 10 p.

Research output: Contribution to journalArticle

17 Scopus citations

6,7-disubstituted 2,4-diaminopteridines: Novel inhibitors of Pneumocystis carinii and Toxoplasma gondii dihydrofolate reductase

Jackson, H. C., Biggadike, K., McKilligin, E., Kinsman, O. S., Queener, S. F., Lane, A. & Smith, J. E., Jun 1 1996, In : Antimicrobial Agents and Chemotherapy. 40, 6, p. 1371-1375 5 p.

Research output: Contribution to journalArticle

14 Scopus citations

670 Nanometer light treatment attenuates dioxin toxicity in the developing chick embryo

Yeager, R. L., Lim, J., Millsap, D. S., Jasevicius, A. V., Sanders, R. A., Whelan, H. T., Watkins, J. B., Eells, J. T. & Henshel, D. S., Dec 1 2006, In : Journal of Biochemical and Molecular Toxicology. 20, 6, p. 271-278 8 p.

Research output: Contribution to journalArticle

14 Scopus citations
66 Scopus citations
45 Scopus citations

7-Methyl trimethoprim analogues as inhibitors of the folate metabolizing enzymes

Gangjee, A., Lin, X. & Queener, S. F., Jan 1 2003, In : Journal of Heterocyclic Chemistry. 40, 3, p. 507-512 6 p.

Research output: Contribution to journalArticle

4 Scopus citations

8-Aminoquinolines effective against Pneumocystis carinii in vitro and in vivo

Queener, S. F., Bartlett, M. S., Nasr, M. & Smith, J. W., Jan 1 1993, In : Antimicrobial Agents and Chemotherapy. 37, 10, p. 2166-2172 7 p.

Research output: Contribution to journalArticle

Open Access
30 Scopus citations

8-Aminoquinolines from Walter Reed Army Institute for Research for treatment and prophylaxis of Pneumocystis pneumonia in rat models

Bartlett, M. S., Queener, S. F., Tidwell, R. R., Milhous, W. K., Berman, J. D., Ellis, W. Y. & Smith, J. W., Jan 1 1991, In : Antimicrobial Agents and Chemotherapy. 35, 2, p. 277-282 6 p.

Research output: Contribution to journalArticle

Open Access
32 Scopus citations

Aberrant epilepsy-associated mutant Nav1.6 sodium channel activity can be targeted with cannabidiol

Patel, R. R., Barbosa, C., Brustovetsky, T., Brustovetsky, N. & Cummins, T. R., Aug 1 2016, In : Brain. 139, 8, p. 2164-2181 18 p.

Research output: Contribution to journalArticle

42 Scopus citations

Ablation of XP-V gene causes adipose tissue senescence and metabolic abnormalities

Chen, Y. W., Harris, R. A., Hatahet, Z. & Chou, K. M., Aug 18 2015, In : Proceedings of the National Academy of Sciences of the United States of America. 112, 33, p. E4556-E4564

Research output: Contribution to journalArticle

15 Scopus citations

Absence of coupling between D2 dopamine receptors and calcium channels in lactotrophs from cycling female rats

Rendt, J. & Oxford, G. S., Aug 1994, In : Endocrinology. 135, 2, p. 501-508 8 p.

Research output: Contribution to journalArticle

9 Scopus citations

A chromosomal integration system for development of polyvalent vaccine strains

Tu, H. L., Li, S. Q., Dong, Z. Z. & Zhang, Z. S., Dec 1 1998, In : Acta Genetica Sinica. 25, 6, p. 557-558 2 p.

Research output: Contribution to journalArticle

1 Scopus citations

A controlled trial of the cost benefit of computerized bayesian aminoglycosde administration

Burton, M. E., Ash, C. L., Hill, D. P., Handy, T. R., Shepherd, M. D. & Vasko, M. R., Jun 1991, In : Clinical Pharmacology and Therapeutics. 49, 6, p. 685-694 10 p.

Research output: Contribution to journalArticle

71 Scopus citations

Action of zolpidem on responses to GABA in relation to mRNAs for GABA(A) receptor alpha subunits within single cells: Evidence for multiple functional GABA(A) isoreceptors on individual neurons

Criswell, H. E., McCown, T. J., Moy, S. S., Oxford, G. S., Mueller, R. A., Morrow, A. L. & Breese, G. R., Jan 1 1997, In : Neuropharmacology. 36, 11-12, p. 1641-1652 12 p.

Research output: Contribution to journalArticle

24 Scopus citations

Activation and inactivation of the voltage-gated sodium channel: Role of segment S5 revealed by a novel hyperkalaemic periodic paralysis mutation

Bendahhou, S., Cummins, T. R., Tawil, R., Waxman, S. G. & Ptácek, L. J., Jun 15 1999, In : Journal of Neuroscience. 19, 12, p. 4762-4771 10 p.

Research output: Contribution to journalArticle

Open Access
69 Scopus citations

Activation and recovery of the PGE2-mediated sensitization of the capsaicin response in rat sensory neurons

Lopshire, J. C. & Nicol, G. D., Dec 1997, In : Journal of Neurophysiology. 78, 6, p. 3154-3164 11 p.

Research output: Contribution to journalArticle

67 Scopus citations

Activation of calcium-independent phospholipase a2 (iPLA 2) in brain mitochondria and release of apoptogenic factors by BAX and truncated BID

Brustovetsky, T., Antonsson, B., Jemmerson, R., Dubinsky, J. M. & Brustovetsky, N., Aug 1 2005, In : Journal of Neurochemistry. 94, 4, p. 980-994 15 p.

Research output: Contribution to journalArticle

48 Scopus citations

Activation of epidermal vanilloid receptor-1 induces release of proinflammatory mediators in human keratinocytes

Southall, M. D., Li, T., Gharibova, L. S., Pei, Y., Nicol, G. D. & Travers, J. B., Jan 1 2003, In : Journal of Pharmacology and Experimental Therapeutics. 304, 1, p. 217-222 6 p.

Research output: Contribution to journalArticle

238 Scopus citations

Activation of human D3 dopamine receptor inhibits P/Q-type calcium channels and secretory activity in AtT-20 cells

Kuzhikandathil, E. V. & Oxford, G. S., Mar 1 1999, In : Journal of Neuroscience. 19, 5, p. 1698-1707 10 p.

Research output: Contribution to journalArticle

48 Scopus citations

Activation of protein kinase C augments peptide release from rat sensory neurons

Barber, L. A. & Vasko, M. R., Jul 1996, In : Journal of Neurochemistry. 67, 1, p. 72-80 9 p.

Research output: Contribution to journalArticle

83 Scopus citations

Activation of protein kinase C enhances peptide release from rat spinal cord slices

Frayer, S. M., Barber, L. A. & Vasko, M. R., Apr 9 1999, In : Neuroscience Letters. 265, 1, p. 17-20 4 p.

Research output: Contribution to journalArticle

17 Scopus citations

Activin acutely sensitizes dorsal root ganglion neurons and induces hyperalgesia via PKC-mediated potentiation of transient receptor potential vanilloid I

Zhu, W., Xu, P., Cuascut, F. X., Hall, A. K. & Oxford, G. S., Dec 12 2007, In : Journal of Neuroscience. 27, 50, p. 13770-13780 11 p.

Research output: Contribution to journalArticle

40 Scopus citations

Activity of clindamycin with primaquine against Pneumocystis carinii in vitro and in vivo

Queener, S. F., Bartlett, M. S., Richardson, J. D., Durkin, M. M., Jay, M. A. & Smith, J. W., Jan 1 1988, In : Antimicrobial Agents and Chemotherapy. 32, 6, p. 807-813 7 p.

Research output: Contribution to journalArticle

Open Access
64 Scopus citations

Activity of inosine analogs against Pneumocystis carinii in culture

Bartlett, M. S., Marr, J. J., Queener, S. F., Klein, R. S. & Smith, J. W., 1986, In : Antimicrobial Agents and Chemotherapy. 30, 1, p. 181-183 3 p.

Research output: Contribution to journalArticle

Open Access
12 Scopus citations

Activity of lipid-soluble inhibitors of dihydrofolate reductase against Pneumocystis carinii in culture and in a rat model of infection

Queener, S. F., Bartlett, M. S., Jay, M. A., Durkin, M. M. & Smith, J. W., Jan 1 1987, In : Antimicrobial Agents and Chemotherapy. 31, 9, p. 1323-1327 5 p.

Research output: Contribution to journalArticle

Open Access
57 Scopus citations

A Culture Method Allowing Production of Relatively Pure Pneumocystis carinii Trophozoites

DL'RKIN, MICHELLE. M., BARTLETT, MARILYN. S., QUEENER, SHERRY. F., SHAW, MARGARET. M. & SMITH, JAMES. W., Jan 1989, In : The Journal of Protozoology. 36, 1, p. 31S-32S

Research output: Contribution to journalArticle

5 Scopus citations

Acute bacterial inflammation of the mouse prostate

Boehm, B. J., Colopy, S. A., Jerde, T. J., Loftus, C. J. & Bushman, W., Feb 1 2012, In : Prostate. 72, 3, p. 307-317 11 p.

Research output: Contribution to journalArticle

49 Scopus citations

Adapting AlphaLISA high throughput screen to discover a novel small-molecule inhibitor targeting protein arginine methyltransferase 5 in pancreatic and colorectal cancers

Prabhu, L., Wei, H., Chen, L., Demir, Ö., Sandusky, G., Sun, E., Wang, J., Mo, J., Zeng, L., Fishel, M., Safa, A., Amaro, R., Korc, M., Zhang, Z. Y. & Lu, T., Jan 1 2017, In : Oncotarget. 8, 25, p. 39963-39977 15 p.

Research output: Contribution to journalArticle

9 Scopus citations
15 Scopus citations

A developmental switch in acute sensitization of small dorsal root ganglion (DRG) neurons to capsaicin or noxious heating by NGF

Zhu, W., Galoyan, S. M., Petruska, J. C., Oxford, G. S. & Mendell, L. M., Nov 1 2004, In : Journal of Neurophysiology. 92, 5, p. 3148-3152 5 p.

Research output: Contribution to journalArticle

56 Scopus citations

A Dose-escalation Study of Recombinant Human Interleukin-18 in Combination with Ofatumumab after Autologous Peripheral Blood Stem Cell Transplantation for Lymphoma

Robertson, M. J., Stamatkin, C. W., Pelloso, D., Weisenbach, J., Prasad, N. K. & Safa, A. R., Jan 1 2018, In : Journal of Immunotherapy. 41, 3, p. 151-157 7 p.

Research output: Contribution to journalArticle

1 Scopus citations

A double mutation in families with periodic paralysis defines new aspects of sodium channel slow inactivation

Bendahhou, S., Cummins, T. R., Hahn, A. F., Langlois, S., Waxman, S. G. & Ptácek, L. J., 2000, In : Journal of Clinical Investigation. 106, 3, p. 431-438 8 p.

Research output: Contribution to journalArticle

Open Access
36 Scopus citations

Adrenergically mediated intrapancreatic control of the glucagon response to glucopenia in the isolated rat pancreas

Hisatomi, A., Maruyama, H., Orci, L., Vasko, M. & Unger, R. H., 1985, In : Journal of Clinical Investigation. 75, 2, p. 420-426 7 p.

Research output: Contribution to journalArticle

Open Access
37 Scopus citations

Advanced glycation end (AGE) product modification of laminin downregulates Kir4.1 in retinal Müller cells

Thompson, K., Chen, J., Luo, Q., Xiao, Y., Cummins, T. & Bhatwadekar, A., Feb 1 2018, In : PLoS One. 13, 2, e0193280.

Research output: Contribution to journalArticle

7 Scopus citations

A Forward Genetic Screen Reveals that Calcium-dependent Protein Kinase 3 Regulates Egress in Toxoplasma

Garrison, E., Treeck, M., Ehret, E., Butz, H., Garbuz, T., Oswald, B. P., Settles, M., Boothroyd, J. & Arrizabalaga, G., Nov 1 2012, In : PLoS pathogens. 8, 11, e1003049.

Research output: Contribution to journalArticle

77 Scopus citations