Pharmacology & Toxicology

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46 Scopus citations

Identification of 14-3-3σ as a contributor to drug resistance in human breast cancer cells using functional proteomic analysis

Liu, Y., Liu, H., Han, B. & Zhang, J. T., Mar 15 2006, In : Cancer Research. 66, 6, p. 3248-3255 8 p.

Research output: Contribution to journalArticle

89 Scopus citations

Identification of a 170-kDa protein over-expressed in lung cancers

Pincheira, R., Chen, Q. & Zhang, J. T., Jun 1 2001, In : British Journal of Cancer. 84, 11, p. 1520-1527 8 p.

Research output: Contribution to journalArticle

83 Scopus citations
Open Access
30 Scopus citations

Identification of fis1 interactors in Toxoplasma gondii reveals a novel protein required for peripheral distribution of the mitochondrion

Jacobs, K., Charvat, R. & Arrizabalaga, G., Jan 1 2020, In : mBio. 11, 1, e02732-19.

Research output: Contribution to journalArticle

Open Access
1 Scopus citations

Identification of highly potent and selective inhibitors of Toxoplasma gondii dihydrofolate reductase

Chio, L. C. & Queener, S. F., 1993, In : Antimicrobial Agents and Chemotherapy. 37, 9, p. 1914-1923 10 p.

Research output: Contribution to journalArticle

Open Access
92 Scopus citations

Identification of novel small molecule inhibitors of the XPA protein using in silico based screening

Neher, T. M., Shuck, S. C., Liu, J. Y., Zhang, J. T. & Turchi, J. J., Oct 15 2010, In : ACS chemical biology. 5, 10, p. 953-965 13 p.

Research output: Contribution to journalArticle

23 Scopus citations

Identification of proteins interacting with Toxoplasma SRCAP by yeast two-hybrid screening

Nallani, K. C. & Sullivan, W. J., Mar 1 2005, In : Parasitology Research. 95, 4, p. 236-242 7 p.

Research output: Contribution to journalArticle

9 Scopus citations

Identification of the benzyloxyphenyl pharmacophore: A structural unit that promotes sodium channel slow inactivation

King, A. M., Yang, X. F., Wang, Y., Dustrude, E. T., Barbosa, C., Due, M. R., Piekarz, A. D., Wilson, S. M., White, F. A., Salomé, C., Cummins, T. R., Khanna, R. & Kohn, H., Dec 19 2012, In : ACS Chemical Neuroscience. 3, 12, p. 1037-1049 13 p.

Research output: Contribution to journalArticle

8 Scopus citations

Identification of the multidrug resistance-related membrane glycoprotein as an acceptor for calcium channel blockers

Safa, A. R., Glover, C. J., Sewell, J. L., Meyers, M. B., Biedler, J. L. & Felsted, R. L., 1987, In : Journal of Biological Chemistry. 262, 16, p. 7884-7888 5 p.

Research output: Contribution to journalArticle

293 Scopus citations

Identification of vimentin as a primaquine-binding protein from pneumocystis cakinii

Queener, S. F. & Bolvard, L. A., Dec 1 1997, In : FASEB Journal. 11, 9, p. A1269

Research output: Contribution to journalArticle

Ifenprodil, a NR2B-selective antagonist of NMDA receptor, inhibits reverse Na+/Ca2+ exchanger in neurons

Brittain, M. K., Brustovetsky, T., Brittain, J. M., Khanna, R., Cummins, T. R. & Brustovetsky, N., Nov 2012, In : Neuropharmacology. 63, 6, p. 974-982 9 p.

Research output: Contribution to journalArticle

17 Scopus citations
39 Scopus citations

Impact of the basic amine on the biological activity and intracellular distribution of an aza-anthrapyrazole: BBR 3422

Chou, K. M., Paul Krapcho, A. & Hacker, M. P., Dec 15 2001, In : Biochemical Pharmacology. 62, 10, p. 1337-1343 7 p.

Research output: Contribution to journalArticle

8 Scopus citations

Impairment of slow inactivation as a common mechanism for periodic paralysis in dIIS4-S5

Bendahhou, S., Cummins, T. R., Kula, R. W., Fu, Y. H. & Ptácek, L. J., Apr 23 2002, In : Neurology. 58, 8, p. 1266-1272 7 p.

Research output: Contribution to journalArticle

59 Scopus citations

IMP dehydrogenase from Pneumocystis carinii as a potential drug target

O'Gara, M. J., Lee, C. H., Weinberg, G. A., Nott, J. M. & Queener, S. F., Jan 1997, In : Antimicrobial Agents and Chemotherapy. 41, 1, p. 40-48 9 p.

Research output: Contribution to journalArticle

Open Access
31 Scopus citations

IMP dehydrogenase from the protozoan parasite Toxoplasma gondii

Sullivan, W. J., Dixon, S. E., Li, C., Striepen, B. & Queener, S. F., Jun 2005, In : Antimicrobial Agents and Chemotherapy. 49, 6, p. 2172-2179 8 p.

Research output: Contribution to journalArticle

28 Scopus citations
90 Scopus citations

Improved rat model for studying Pneumocystis carinii pneumonia

Bartlett, M. S., Queener, S. F., Jay, M. A., Durkin, M. M. & Smith, J. W., 1987, In : Journal of clinical microbiology. 25, 3, p. 480-484 5 p.

Research output: Contribution to journalArticle

Open Access
18 Scopus citations

Inclusion of a competency-based curriculum in medical pharmacology

Near, J. A., Bosin, T. R. & Watkins, J. B., Jun 26 2002, In : Naunyn-Schmiedeberg's Archives of Pharmacology. 366, 1, p. 26-29 4 p.

Research output: Contribution to journalArticle

2 Scopus citations

Incorporation of Fatty Acids and Amino Acids by Cultured Pneumocystis carinii

PAULSRUD, JOHN. R. & QUEENER, SHERRY. F., Nov 1994, In : Journal of Eukaryotic Microbiology. 41, 6, p. 633-638 6 p.

Research output: Contribution to journalArticle

17 Scopus citations
18 Scopus citations

Increased resurgent sodium currents in nav1.8 contribute to nociceptive sensory neuron hyperexcitability associated with peripheral neuropathies

Xiao, Y., Barbosa, C., Pei, Z., Xie, W., Strong, J. A., Zhang, J. M. & Cummins, T. R., Feb 20 2019, In : Journal of Neuroscience. 39, 8, p. 1539-1550 12 p.

Research output: Contribution to journalArticle

7 Scopus citations

Induction of UDP-glucuronosyltransferase activities in Gunn, heterozygous, and Wistar rat livers by pregnenolone-16α-carbonitrile

Watkins, J. B. & Klaassen, C. D., Dec 1 1982, In : Drug Metabolism and Disposition. 10, 6, p. 590-594 5 p.

Research output: Contribution to journalArticle

44 Scopus citations

Induction studies on the functional heterogeneity of rat liver UDP-glucuronosyltransferases

Watkins, J. B., Gregus, Z., Thompson, T. N. & Klaassen, C. D., Jul 1982, In : Toxicology and Applied Pharmacology. 64, 3, p. 439-446 8 p.

Research output: Contribution to journalArticle

95 Scopus citations
5 Scopus citations

Influence of treatment of diabetic rats with combinations of pycnogenol, β-carotene, and α-lipoic acid on parameters of oxidative stress

Berryman, A. M., Maritim, A. C., Sanders, R. A. & Watkins, J. B., Jan 1 2005, In : Journal of Biochemical and Molecular Toxicology. 18, 6, p. 345-352 8 p.

Research output: Contribution to journalArticle

31 Scopus citations

Inhibiting the Plasmodium eIF2α Kinase PK4 Prevents Artemisinin-Induced Latency

Zhang, M., Gallego-Delgado, J., Fernandez-Arias, C., Waters, N. C., Rodriguez, A., Tsuji, M., Wek, R. C., Nussenzweig, V. & Sullivan, W. J., Dec 13 2017, In : Cell Host and Microbe. 22, 6, p. 766-776.e4

Research output: Contribution to journalArticle

32 Scopus citations
10 Scopus citations

Inhibition of Nav1.7 and Nav1.4 sodium channels by trifluoperazine involves the local anesthetic receptor

Sheets, P. L., Gerner, P., Wang, C. F., Wang, S. Y., Ging, K. W. & Cummins, T. R., Oct 1 2006, In : Journal of Neurophysiology. 96, 4, p. 1848-1859 12 p.

Research output: Contribution to journalArticle

14 Scopus citations

Inhibition of Navβ4 peptide-mediated resurgent sodium currents in Nav1.7 channels by carbamazepine, riluzole, and anandamide

Theile, J. W. & Cummins, T. R., Oct 1 2011, In : Molecular Pharmacology. 80, 4, p. 724-734 11 p.

Research output: Contribution to journalArticle

48 Scopus citations
44 Scopus citations
6 Scopus citations

Inhibition of the Ubc9 E2 SUMO-conjugating enzyme-CRMP2 interaction decreases NaV1.7 currents and reverses experimental neuropathic pain

Francois-Moutal, L., Dustrude, E. T., Wang, Y., Brustovetsky, T., Dorame, A., Ju, W., Moutal, A., Perez-Miller, S., Brustovetsky, N., Gokhale, V., Khanna, M. & Khanna, R., Jan 1 2018, In : Pain. 159, 10, p. 2115-2127 13 p.

Research output: Contribution to journalArticle

20 Scopus citations

Inhibition of WY-14,643 induced hepatic lesion growth in mice by rotenone

Isenberg, J. S., Kolaja, K. L., Ayoubi, S. A., Watkins, J. B. & Klaunig, J. E., Aug 1 1997, In : Carcinogenesis. 18, 8, p. 1511-1519 9 p.

Research output: Contribution to journalArticle

30 Scopus citations
21 Scopus citations

Inhibitory effects of clonidine and tizanidine on release of substance P from slices of rat spinal cord and antagonism by α-adrenergic receptor antagonists

Ono, H., Mishima, A., Ono, S., Fukuda, H. & Vasko, M. R., Jun 1991, In : Neuropharmacology. 30, 6, p. 585-589 5 p.

Research output: Contribution to journalArticle

83 Scopus citations

Inoculated mouse model of Pneumocystis carinii infection

Bartlett, M. S., Queener, S. F., Durkin, M. M., Shaw, M. A. & Smith, J. W., Feb 1992, In : Diagnostic Microbiology and Infectious Disease. 15, 2, p. 129-134 6 p.

Research output: Contribution to journalArticle

23 Scopus citations

Inoculated mouse model of Pneumocystis carinii pneumonia.

Bartlett, M. S., Queener, S. F., Durkin, M. M., Shaw, M. M. & Smith, J. W., 1991, In : The Journal of Protozoology. 38, 6, p. 130S-131S

Research output: Contribution to journalArticle

2 Scopus citations

In Silico docking and electrophysiological characterization of lacosamide binding sites on collapsin response mediator protein-2 identifies a pocket important in modulating sodium channel slow inactivation

Wang, Y., Brittain, J. M., Jarecki, B. W., Park, K. D., Wilson, S. M., Wang, B., Hale, R., Meroueh, S. O., Cummins, T. R. & Khanna, R., Aug 13 2010, In : Journal of Biological Chemistry. 285, 33, p. 25296-25307 12 p.

Research output: Contribution to journalArticle

61 Scopus citations

Integration of pharmacology into a problem–based learning curriculum for medical students

Sivam, S. P., Iatridis, P. G. & Vaughn, S., Jul 1995, In : Medical Education. 29, 4, p. 289-296 8 p.

Research output: Contribution to journalArticle

33 Scopus citations

Interaction between DNA polymerase λ and anticancer nucleoside analogs

Garcia-Diaz, M., Murray, M. S., Kunkel, T. A. & Chou, K. M., May 28 2010, In : Journal of Biological Chemistry. 285, 22, p. 16874-16879 6 p.

Research output: Contribution to journalArticle

12 Scopus citations

Interaction of a DDT analog with the sodium channel of lobster axon

Wu, C. H., Oxford, G. S., Narahashi, T. & Holan, G., 1980, In : Journal of Pharmacology and Experimental Therapeutics. 212, 2, p. 287-293 7 p.

Research output: Contribution to journalArticle

10 Scopus citations

Interaction of internal anions with potassium channels of the squid giant axon

Adams, D. J. & Oxford, G. S., Oct 1 1983, In : Journal of General Physiology. 82, 4, p. 429-448 20 p.

Research output: Contribution to journalArticle

Open Access
20 Scopus citations

Interactions of aminopyridines with potassium channels of squid axon membranes

Yeh, J. Z., Oxford, G. S., Wu, C. H. & Narahashi, T., 1976, In : Biophysical journal. 16, 1, p. 77-81 5 p.

Research output: Contribution to journalArticle

Open Access
167 Scopus citations

Interactions of monovalent cations with sodium channels in squid axon: I. Modification of physiological inactivation gating

Oxford, G. S. & Yeh, J. Z., Apr 1 1985, In : Journal of General Physiology. 85, 4, p. 583-602 20 p.

Research output: Contribution to journalArticle

Open Access
24 Scopus citations

Interactions of monovalent cations with sodium channels in squid axon: II. Modification of pharmacological inactivation gating

Yeh, J. Z. & Oxford, G. S., Apr 1 1985, In : Journal of General Physiology. 85, 4, p. 603-620 18 p.

Research output: Contribution to journalArticle

Open Access
7 Scopus citations

Interactions of peripheral endothelin-1 and nerve growth factor as contributors to persistent Cutaneous Pain

Khodorova, A., Zhang, Y., Nicol, G. & Strichartz, G., 2018, In : Physiological Research. 67, p. S215-S225

Research output: Contribution to journalArticle

Open Access
1 Scopus citations

Interleukin-driven insulin-like growth factor promotes prostatic inflammatory hyperplasia

Hahn, A. M., Myers, J. D., McFarland, E. K., Lee, S. & Jerde, T. J., Dec 1 2014, In : Journal of Pharmacology and Experimental Therapeutics. 351, 3, p. 606-615 10 p.

Research output: Contribution to journalArticle

8 Scopus citations

Internal and external application of photodynamic sensitizers on squid giant axons

Oxford, G. S., Pooler, J. P. & Narahashi, T., Dec 1977, In : The Journal of Membrane Biology. 36, 1, p. 159-173 15 p.

Research output: Contribution to journalArticle

37 Scopus citations