Pharmacology & Toxicology

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Acute bacterial inflammation of the mouse prostate

Boehm, B. J., Colopy, S. A., Jerde, T. J., Loftus, C. J. & Bushman, W., Feb 1 2012, In : Prostate. 72, 3, p. 307-317 11 p.

Research output: Contribution to journalArticle

47 Scopus citations

Acute effects of mitoxantrone on the template activity of isolated nuclei from the T-47D human breast tumor cell line

Chegini, N., Safa, A. R. & Tseng, M. T., Jan 1984, In : Cancer Letters. 21, 3, p. 329-336 8 p.

Research output: Contribution to journalArticle

5 Scopus citations

Acute toxicity of Soman, Sarin and Tabun: Neurochemical evaluations related to cholinergic, GABAergic and dopamine systems

Sivam, S. P., Lim, D. K., Hoskins, B. & Ho, I. K., Jan 1 1984, In : Federation Proceedings. 43, 3, p. no. 1635

Research output: Contribution to journalArticle

Adapting AlphaLISA high throughput screen to discover a novel small-molecule inhibitor targeting protein arginine methyltransferase 5 in pancreatic and colorectal cancers

Prabhu, L., Wei, H., Chen, L., Demir, Ö., Sandusky, G., Sun, E., Wang, J., Mo, J., Zeng, L., Fishel, M., Safa, A., Amaro, R., Korc, M., Zhang, Z-Y. & Lu, T., 2017, In : Oncotarget. 8, 25, p. 39963-39977 15 p.

Research output: Contribution to journalArticle

8 Scopus citations
15 Scopus citations

A derivative of amiloride blocks both the light-regulated and cyclic GMP-regulated conductances in rod photoreceptors

Nicol, G. D., Schnetkamp, P. P. M., Saimi, Y., Cragoe, E. J. & Bownds, M. D., Nov 1 1987, In : Journal of General Physiology. 90, 5, p. 651-669 19 p.

Research output: Contribution to journalArticle

Open Access
45 Scopus citations

A developmental switch in acute sensitization of small dorsal root ganglion (DRG) neurons to capsaicin or noxious heating by NGF

Zhu, W., Galoyan, S. M., Petruska, J. C., Oxford, G. S. & Mendell, L. M., Nov 1 2004, In : Journal of Neurophysiology. 92, 5, p. 3148-3152 5 p.

Research output: Contribution to journalArticle

55 Scopus citations

A Dose-escalation Study of Recombinant Human Interleukin-18 in Combination with Ofatumumab after Autologous Peripheral Blood Stem Cell Transplantation for Lymphoma

Robertson, M. J., Stamatkin, C. W., Pelloso, D., Weisenbach, J., Prasad, N. K. & Safa, A. R., Jan 1 2018, In : Journal of Immunotherapy. 41, 3, p. 151-157 7 p.

Research output: Contribution to journalArticle

1 Scopus citations

A double mutation in families with periodic paralysis defines new aspects of sodium channel slow inactivation

Bendahhou, S., Cummins, T. R., Hahn, A. F., Langlois, S., Waxman, S. G. & Ptácek, L. J., Jan 1 2000, In : Journal of Clinical Investigation. 106, 3, p. 431-438 8 p.

Research output: Contribution to journalArticle

Open Access
36 Scopus citations

Adrenergically mediated intrapancreatic control of the glucagon response to glucopenia in the isolated rat pancreas

Hisatomi, A., Maruyama, H., Orci, L., Vasko, M. & Unger, R. H., Jan 1 1985, In : Journal of Clinical Investigation. 75, 2, p. 420-426 7 p.

Research output: Contribution to journalArticle

Open Access
36 Scopus citations

Advanced glycation end (AGE) product modification of laminin downregulates Kir4.1 in retinal Müller cells

Thompson, K., Chen, J., Luo, Q., Xiao, Y., Cummins, T. & Bhatwadekar, A., Feb 1 2018, In : PLoS One. 13, 2, e0193280.

Research output: Contribution to journalArticle

4 Scopus citations

A Forward Genetic Screen Reveals that Calcium-dependent Protein Kinase 3 Regulates Egress in Toxoplasma

Garrison, E., Treeck, M., Ehret, E., Butz, H., Garbuz, T., Oswald, B. P., Settles, M., Boothroyd, J. & Arrizabalaga, G., Nov 1 2012, In : PLoS pathogens. 8, 11, e1003049.

Research output: Contribution to journalArticle

77 Scopus citations

A frequency analysis of behavior components of the serotonin syndrome produced by p-chloroamphetamine

Kutscher, C. L. & Yamamoto, B. K., Dec 1979, In : Pharmacology, Biochemistry and Behavior. 11, 6, p. 611-616 6 p.

Research output: Contribution to journalArticle

12 Scopus citations

A gain-of-function mutation in the sodium channel gene Scn2a results in seizures and behavioral abnormalities

Kearney, J. A., Plummer, N. W., Smith, M. R., Kapur, J., Cummins, T. R., Waxman, S. G., Goldin, A. L. & Meisler, M. H., Jan 15 2001, In : Neuroscience. 102, 2, p. 307-317 11 p.

Research output: Contribution to journalArticle

169 Scopus citations

A GCN2-Like eukaryotic initiation factor 2 kinase increases the viability of extracellular toxoplasma gondii parasites

Konrad, C., Wek, R. C. & Sullivan, W. J., Nov 1 2011, In : Eukaryotic Cell. 10, 11, p. 1403-1412 10 p.

Research output: Contribution to journalArticle

28 Scopus citations

Age-dependent changes in the calcium sensitivity of striatal mitochondria in mouse models of Huntington's disease

Brustovetsky, N., LaFrance, R., Purl, K. J., Brustovetsky, T., Keene, C. D., Low, W. C. & Dubinsky, J. M., Jun 1 2005, In : Journal of Neurochemistry. 93, 6, p. 1361-1370 10 p.

Research output: Contribution to journalArticle

80 Scopus citations

A genetic screen in Caenorhabditis elegans for dopamine neuron insensitivity to 6-hydroxydopamine identifies dopamine transporter mutants impacting transporter biosynthesis and trafficking

Nass, R., Hahn, M. K., Jessen, T., McDonald, P. W., Carvelli, L. & Blakely, R. D., Aug 1 2005, In : Journal of Neurochemistry. 94, 3, p. 774-785 12 p.

Research output: Contribution to journalArticle

53 Scopus citations

Age-related changes in regional brain mitochondria from Fischer 344 rats

LaFrance, R., Brustovetsky, N., Sherburne, C., DeLong, D. & Dubinsky, J. M., Jun 1 2005, In : Aging Cell. 4, 3, p. 139-145 7 p.

Research output: Contribution to journalArticle

34 Scopus citations

A-kinase anchoring protein mediates TRPV1 thermal hyperalgesia through PKA phosphorylation of TRPV1

Jeske, N. A., Diogenes, A., Ruparel, N. B., Fehrenbacher, J. C., Henry, M., Akopian, A. N. & Hargreaves, K. M., Sep 15 2008, In : Pain. 138, 3, p. 604-616 13 p.

Research output: Contribution to journalArticle

77 Scopus citations

A large Ca2+-dependent channel formed by recombinant ADP/ATP carrier from Neurospora crassa resembles the mitochondrial permeability transition pore

Brustovetsky, N., Tropschug, M., Heimpel, S., Heidkämper, D. & Klingenberg, M., Oct 1 2002, In : Biochemistry. 41, 39, p. 11804-11811 8 p.

Research output: Contribution to journalArticle

88 Scopus citations

A latent ability to persist: differentiation in Toxoplasma gondii

Jeffers, V., Tampaki, Z., Kim, K. & Sullivan, W., Mar 30 2018, (Accepted/In press) In : Cellular and Molecular Life Sciences. p. 1-19 19 p.

Research output: Contribution to journalArticle

17 Scopus citations

Albendazole inhibits Pneumocystis carinii proliferation in inoculated immunosuppressed mice

Bartlett, M. S., Edlind, T. D., Lee, C. H., Dean, R., Queener, S. F., Shaw, M. M. & Smith, J. W., Jan 1 1994, In : Antimicrobial Agents and Chemotherapy. 38, 8, p. 1834-1837 4 p.

Research output: Contribution to journalArticle

Open Access
20 Scopus citations

Alcohol‐Induced Inhibition of Alveolar Macrophage Oxidant Release in Vivo and in Vitro

Antony, V. B., Godbey, S. W., Hott, J. W. & Queener, S. F., Apr 1993, In : Alcoholism: Clinical and Experimental Research. 17, 2, p. 389-393 5 p.

Research output: Contribution to journalArticle

26 Scopus citations

Alterations in adult behavioral responses to cocaine and dopamine transporters following juvenile exposure to methamphetamine

McFadden, L., Yamamoto, B. K. & Matuszewich, L., Jan 20 2011, In : Behavioural Brain Research. 216, 2, p. 726-730 5 p.

Research output: Contribution to journalArticle

6 Scopus citations

Alterations in biliary excretory function by streptozotocin-induced diabetes

Watkins, J. B. & Dykstra, T. P., Jan 1 1987, In : Drug Metabolism and Disposition. 15, 2, p. 177-183 7 p.

Research output: Contribution to journalArticle

36 Scopus citations

Alterations in respiratory behavior, brain neurochemistry and receptor density induced by pharmacologic suppression of sleep in the neonatal period

Thomas, A. J., Erokwu, B. O., Yamamoto, B. K., Ernsberger, P., Bishara, O. & Strohl, K. P., Apr 14 2000, In : Developmental Brain Research. 120, 2, p. 181-189 9 p.

Research output: Contribution to journalArticle

17 Scopus citations

Alterations of regional γ-aminobutyric acid receptors in morphine tolerant mice

Sivam, S. P., Nabeshima, T. & Ho, I. K., Aug 1 1981, In : Biochemical Pharmacology. 30, 15, p. 2187-2190 4 p.

Research output: Contribution to journalArticle

22 Scopus citations
12 Scopus citations

Altered excitability and local connectivity of mPFC-PAG neurons in a mouse model of neuropathic pain

Cheriyan, J. & Sheets, P. L., May 16 2018, In : Journal of Neuroscience. 38, 20, p. 4829-4839 11 p.

Research output: Contribution to journalArticle

18 Scopus citations

Altered forebrain neurotransmitter responses to immobilization stress following 3,4-methylenedioxymethamphetamine

Matuszewich, L., Filon, M. E., Finn, D. A. & Yamamoto, B. K., Mar 1 2002, In : Neuroscience. 110, 1, p. 41-48 8 p.

Research output: Contribution to journalArticle

40 Scopus citations

Altered saccharin preference during chronic dietary administration of lead in adult rats

Kutscher, C. L. & Yamamoto, B. K., Dec 1 1979, In : Neurobehavioral Toxicology and Teratology. 1, 4, p. 259-262 4 p.

Research output: Contribution to journalArticle

6 Scopus citations

Alternative splicing of NaV1.7 exon 5 increases the impact of the painful PEPD mutant channel I1461T

Jarecki, B. W., Sheets, P. L., Xiao, Y., Jackson, J. O. & Cummins, T. R., Jan 1 2009, In : Channels. 3, 4

Research output: Contribution to journalArticle

Open Access
16 Scopus citations

A minimalistic approach to develop new anti-apicomplexa polyamines analogs

Panozzo-Zénere, E. A., Porta, E. O. J., Arrizabalaga, G., Fargnoli, L., Khan, S. I., Tekwani, B. L. & Labadie, G. R., Jan 1 2018, In : European Journal of Medicinal Chemistry. 143, p. 866-880 15 p.

Research output: Contribution to journalArticle

2 Scopus citations

Aminopyridines block an inactivating potassium current having slow recovery kinetics

Wagoner, P. K. & Oxford, G. S., Jan 1 1990, In : Biophysical journal. 58, 6, p. 1481-1489 9 p.

Research output: Contribution to journalArticle

Open Access
27 Scopus citations

Ammonia mediates methamphetamine-induced increases in glutamate and excitotoxicity

Halpin, L. E., Northrop, N. A. & Yamamoto, B. K., Mar 1 2014, In : Neuropsychopharmacology. 39, 4, p. 1031-1038 8 p.

Research output: Contribution to journalArticle

27 Scopus citations

Amylin modulates β-cell glucose sensing via effects on stimulus-secretion coupling

Wagoner, P. K., Chen, C., Worley, J. F., Dukes, I. D. & Oxford, G. S., Oct 1 1993, In : Proceedings of the National Academy of Sciences of the United States of America. 90, 19, p. 9145-9149 5 p.

Research output: Contribution to journalArticle

Open Access
58 Scopus citations
26 Scopus citations

Analgesic cross-tolerance between morphine and opioid peptides

Sivam, S. P. & Ho, I. K., Sep 1 1984, In : Psychopharmacology. 84, 1, p. 64-65 2 p.

Research output: Contribution to journalArticle

9 Scopus citations

Analysis of changes in the proteome of HL-60 promyeloid leukemia cells induced by the proteasome inhibitor PSI

Choi, M. R., Najafi, F., Safa, A. R. & Drexler, H. C. A., Jun 15 2008, In : Biochemical Pharmacology. 75, 12, p. 2276-2288 13 p.

Research output: Contribution to journalArticle

8 Scopus citations

Analysis of monensin sensitivity in toxoplasma gondii reveals autophagy as a mechanism for drug induced death

Lavine, M. D. & Arrizabalaga, G., Jul 25 2012, In : PLoS ONE. 7, 7, e42107.

Research output: Contribution to journalArticle

37 Scopus citations

Analysis of MRP gene expression and function in HL60 cells isolated for resistance to adriamycin

Krishnamachary, N., Ma, L., Zheng, L., Safa, A. R. & Center, M. S., Dec 1 1994, In : Oncology Research. 6, 3, p. 119-127 9 p.

Research output: Contribution to journalArticle

60 Scopus citations

Analysis of quinazoline and pyrido[2,3-d]-pyrimidine N9-C10 reversed-bridge antifolates in complex with NADP+ and Pneumocystis carinii dihydrofolate reductase

Cody, V., Galitsky, N., Luft, J. R., Pangborn, W., Queener, S. F. & Gangjee, A., Sep 1 2002, In : Acta Crystallographica Section D: Biological Crystallography. 58, 9, p. 1393-1399 7 p.

Research output: Contribution to journalArticle

20 Scopus citations

Analysis of sodium fluoride enhancement of calcitonin stimulation of renal cortical adenylate cyclase

Queener, S. F., Fleming, J. W. & Bell, N. H., Dec 1 1978, In : Journal of Biological Chemistry. 253, 24, p. 9033-9040 8 p.

Research output: Contribution to journalArticle

2 Scopus citations
6 Scopus citations

An Analysis of GABA Receptor Changes in the Discrete Regions of Mouse Brain After Acute and Chronic Treatments with Morphine

Sivam, S. P., Nabeshima, T. & Ho, I. K., Oct 1982, In : Journal of Neurochemistry. 39, 4, p. 933-939 7 p.

Research output: Contribution to journalArticle

29 Scopus citations
46 Scopus citations

An atypical role for collapsin response mediator protein 2 (CRMP-2) in neurotransmitter release via interaction with presynaptic voltage-gated calcium channels

Brittain, J. M., Piekarz, A. D., Wang, Y., Kondo, T., Cummins, T. R. & Khanna, R., Nov 6 2009, In : Journal of Biological Chemistry. 284, 45, p. 31375-31390 16 p.

Research output: Contribution to journalArticle

130 Scopus citations

A Nav 1.7 channel mutation associated with hereditary erythromelalgia contributes to neuronal hyperexcitability and displays reduced lidocaine sensitivity

Sheets, P. L., Jackson, J. O., Waxman, S. G., Dib-hajj, S. D. & Cummins, T. R., Jun 1 2007, In : Journal of Physiology. 581, 3, p. 1019-1031 13 p.

Research output: Contribution to journalArticle

126 Scopus citations

An ELISA method for quantitation of Pneumocystis carinii in culture and lung.

Durkin, M. M., Bartlett, M. S., Queener, S. F., Shaw, M. M., Lee, C. H. & Smith, J. W., Jan 1 1991, In : The Journal of Protozoology. 38, 6, p. 208S-210S

Research output: Contribution to journalArticle

1 Scopus citations