Pharmacology & Toxicology

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2004

Suppression of 15-Hydroxyprostaglandin Dehydrogenase Messenger RNA Concentration, Protein Expression, and Enzymatic Activity during Human Ureteral Obstruction

Jerde, T. J., Mellon, W. S., Fischer, S. M., Liebert, M., Bjorling, D. E. & Nakada, S. Y., Apr 1 2004, In : Journal of Pharmacology and Experimental Therapeutics. 309, 1, p. 398-403 6 p.

Research output: Contribution to journalArticle

8 Scopus citations
38 Scopus citations

Taxol induces caspase-10-dependent apoptosis

Park, S. J., Wu, C. H., Gordon, J. D., Zhong, X., Emami, A. & Safa, A. R., Dec 3 2004, In : Journal of Biological Chemistry. 279, 49, p. 51057-51067 11 p.

Research output: Contribution to journalArticle

169 Scopus citations

The Biology and Pharmacology of Calcium Channel α2-δ Proteins Pfizer satellite symposium to the 2003 Society for Neuroscience Meeting Sheraton New Orleans Hotel New Orleans, LA November 10, 2003

Taylor, C. P., Catterall, W. A., Hofmann, F., Luo, Z. D., Wustrow, D. J., Vasko, M., Field, M. & Baron, S., Jun 1 2004, In : CNS Drug Reviews. 10, 2, p. 183-188 6 p.

Research output: Contribution to journalArticle

95 Scopus citations
43 Scopus citations

Tyrosine augments clozapine-induced dopamine release in the medial prefrontal cortex of the rat in vivo: Effects of access to food

Jaskiw, G. E., Simpson, C., Bongiovanni, R. & Yamamoto, B. K., Feb 26 2004, In : Neuroscience Letters. 357, 1, p. 5-8 4 p.

Research output: Contribution to journalArticle

9 Scopus citations
2003

7-Methyl trimethoprim analogues as inhibitors of the folate metabolizing enzymes

Gangjee, A., Lin, X. & Queener, S. F., Jan 1 2003, In : Journal of Heterocyclic Chemistry. 40, 3, p. 507-512 6 p.

Research output: Contribution to journalArticle

4 Scopus citations

Activation of epidermal vanilloid receptor-1 induces release of proinflammatory mediators in human keratinocytes

Southall, M. D., Li, T., Gharibova, L. S., Pei, Y., Nicol, G. D. & Travers, J. B., Jan 1 2003, In : Journal of Pharmacology and Experimental Therapeutics. 304, 1, p. 217-222 6 p.

Research output: Contribution to journalArticle

238 Scopus citations

ATP augments peptide release from rat sensory neurons in culture through activation of P2Y receptors

Huang, H., Wu, X., Nicol, G. D., Meller, S. & Vasko, M. R., Sep 1 2003, In : Journal of Pharmacology and Experimental Therapeutics. 306, 3, p. 1137-1144 8 p.

Research output: Contribution to journalArticle

35 Scopus citations

Bipolar Radiofrequency Ablation of the Kidney: Comparison with Monopolar Radiofrequency Ablation

Nakada, S. Y., Jerde, T. J., Warner, T. F., Wright, A. S., Haemmerich, D., Mahvi, D. M. & Lee, F. T., Dec 2003, In : Journal of Endourology. 17, 10, p. 927-933 7 p.

Research output: Contribution to journalArticle

34 Scopus citations

Calmodulin binds to the C terminus of sodium channels Nav1.4 and Navl.6 and differentially modulates their functional properties

Herzog, R. I., Liu, C., Waxman, S. G. & Cummins, T. R., Sep 10 2003, In : Journal of Neuroscience. 23, 23, p. 8261-8270 10 p.

Research output: Contribution to journalArticle

116 Scopus citations

Catecholaminergic microcircuitry controlling the output of airway-related vagal preganglionic neurons

Haxhiu, M. A., Kc, P., Neziri, B., Yamamoto, B. K., Ferguson, D. G. & Massari, V. J., May 1 2003, In : Journal of Applied Physiology. 94, 5, p. 1999-2009 11 p.

Research output: Contribution to journalArticle

28 Scopus citations

Distinct repriming and closed-state inactivation kinetics of Nav1.6 and Nav1.7 sodium channels in mouse spinal sensory neurons

Herzog, R. I., Cummins, T. R., Ghassemi, F., Dib-Hajj, S. D. & Waxman, S. G., Sep 15 2003, In : Journal of Physiology. 551, 3, p. 741-750 10 p.

Research output: Contribution to journalArticle

233 Scopus citations

Dopaminergic neuronal loss and motor deficits in Caenorhabditis elegans overexpressing human α-synuclein

Lakso, M., Vartiainen, S., Moilanen, A. M., Sirviö, J., Thomas, J. H., Nass, R., Blakely, R. D. & Wong, G., Jul 1 2003, In : Journal of Neurochemistry. 86, 1, p. 165-172 8 p.

Research output: Contribution to journalArticle

248 Scopus citations

Effects of amphetamines on mitochondrial function: Role of free radicals and oxidative stress

Brown, J. M. & Yamamoto, B. K., Jul 1 2003, In : Pharmacology and Therapeutics. 99, 1, p. 45-53 9 p.

Research output: Contribution to journalArticle

136 Scopus citations

Effects of pycnogenol treatment on oxidative stress in streptozotocin-induced diabetic rats

Maritim, A., Dene, B. A., Sanders, R. A. & Watkins, J. B., Jul 18 2003, In : Journal of Biochemical and Molecular Toxicology. 17, 3, p. 193-199 7 p.

Research output: Contribution to journalArticle

74 Scopus citations

Effects of α-lipoic acid on biomarkers of oxidative stress in streptozotocin-induced diabetic rats

Maritim, A. C., Sanders, R. A. & Watkins, J. B., May 1 2003, In : Journal of Nutritional Biochemistry. 14, 5, p. 288-294 7 p.

Research output: Contribution to journalArticle

188 Scopus citations

EIF3 p170, a mediator of mimosine effect on protein synthesis and cell cycle progression

Dong, Z. & Zhang, J. T., Sep 1 2003, In : Molecular Biology of the Cell. 14, 9, p. 3942-3951 10 p.

Research output: Contribution to journalArticle

80 Scopus citations
35 Scopus citations

GTPγS increases Nav1.8 current in small-diameter dorsal root ganglia neurons

Saab, C. Y., Cummins, T. R. & Waxman, S. G., Oct 1 2003, In : Experimental Brain Research. 152, 4, p. 415-419 5 p.

Research output: Contribution to journalArticle

30 Scopus citations
15 Scopus citations

Increased susceptibility of striatal mitochondria to calcium-induced permeability transition

Brustovetsky, N., Brustovetsky, T., Purl, K. J., Capano, M., Crompton, M. & Dubinsky, J. M., Jun 15 2003, In : Journal of Neuroscience. 23, 12, p. 4858-4867 10 p.

Research output: Contribution to journalArticle

122 Scopus citations

Long-lasting effects of chronic stress on doi-induced hyperthermia in male rats

Matuszewich, L. & Yamamoto, B. K., Sep 1 2003, In : Psychopharmacology. 169, 2, p. 169-175 7 p.

Research output: Contribution to journalArticle

36 Scopus citations

Modulation of the cardiac sodium channel Nav1.5 by fibroblast growth factor homologous factor 1B

Liu, C. J., Dib-Hajj, S. D., Renganathan, M., Cummins, T. R. & Waxman, S. G., Jan 10 2003, In : Journal of Biological Chemistry. 278, 2, p. 1029-1036 8 p.

Research output: Contribution to journalArticle

96 Scopus citations

Molecular cloning and characterization of an SRCAP chromatin remodeling homologue in Toxoplasma gondii

Sullivan, W. J., Monroy, M. A., Bohne, W., Nallani, K. C., Chrivia, J., Yaciuk, P., Smith, C. K. & Queener, S. F., May 1 2003, In : Parasitology Research. 90, 1, p. 1-8 8 p.

Research output: Contribution to journalArticle

21 Scopus citations

Oxidative Stress in Rats after 60 Days of Hypergalactosemia or Hyperglycemia

Otsyula, M., King, M. S., Ketcham, T. G., Sanders, R. A. & Watkins, J. B., Jan 1 2003, In : International Journal of Toxicology. 22, 6, p. 423-427 5 p.

Research output: Contribution to journalArticle

14 Scopus citations

Pet-1 ETS gene plays a critical role in 5-HT neuron development and is required for normal anxiety-like and aggressive behavior

Hendricks, T. J., Fyodorov, D. V., Wegman, L. J., Lelutiu, N. B., Pehek, E. A., Yamamoto, B., Silver, J., Weeber, E. J., Sweatt, J. D. & Deneris, E. S., Jan 23 2003, In : Neuron. 37, 2, p. 233-247 15 p.

Research output: Contribution to journalArticle

348 Scopus citations

Pharmacokinetics of systemically administered tyrosine: A comparison of serum, brain tissue and in vivo microdialysate levels in the rat

Bongiovanni, R., Yamamoto, B. K., Simpson, C. & Jaskiw, G. E., Oct 1 2003, In : Journal of Neurochemistry. 87, 2, p. 310-317 8 p.

Research output: Contribution to journalArticle

36 Scopus citations
273 Scopus citations

Prostaglandin E2 inhibits the potassium current in sensory neurons from hyperalgesic Kv1.1 knockout mice

Jiang, X., Zhang, Y. H., Clark, J. D., Tempel, B. L. & Nicol, G. D., Jun 18 2003, In : Neuroscience. 119, 1, p. 65-72 8 p.

Research output: Contribution to journalArticle

17 Scopus citations

Protein kinase C phosphorylation sensitizes but does not activate the capsaicin receptor transient receptor potential vanilloid 1 (TRPV1)

Bhave, G., Hu, H. J., Glauner, K. S., Zhu, W., Wang, H., Brasier, D. J., Oxford, G. S. & Gereau IV, R. W., Oct 14 2003, In : Proceedings of the National Academy of Sciences of the United States of America. 100, 21, p. 12480-12485 6 p.

Research output: Contribution to journalArticle

299 Scopus citations

Regulation of constitutive expression of mouse PTEN by the 5′-untranslated region

Han, B., Dong, Z., Liu, Y., Chen, Q., Hashimoto, K. & Zhang, J. T., Aug 14 2003, In : Oncogene. 22, 34, p. 5325-5337 13 p.

Research output: Contribution to journalArticle

52 Scopus citations

Synaptic and membrane properties of neurons in the dorsomedial hypothalamus

Bailey, T. W., Nicol, G. D., Schild, J. H. & DiMicco, J. A., Sep 26 2003, In : Brain research. 985, 2, p. 150-162 13 p.

Research output: Contribution to journalArticle

16 Scopus citations
55 Scopus citations

Synthesis and DHFR inhibitory activity of a series of 6-substituted-2,4-diaminothieno[2,3-d]pyrimidines

Donkor, I. O., Li, H. & Queener, S. F., Jun 1 2003, In : European Journal of Medicinal Chemistry. 38, 6, p. 605-611 7 p.

Research output: Contribution to journalArticle

43 Scopus citations
89 Scopus citations

Tetrodotoxin-resistant sodium channels Nav1.8/SNS and Nav1.9/NaN in afferent neurons innervating urinary bladder in control and spinal cord injured rats

Black, J. A., Cummins, T. R., Yoshimura, N., De Groat, W. C. & Waxman, S. G., Feb 14 2003, In : Brain research. 963, 1-2, p. 132-138 7 p.

Research output: Contribution to journalArticle

43 Scopus citations

The exonuclease activity of human apurinic/apyrimidinic endonuclease (APE1). Biochemical properties and inhibition by the natural dinucleotide Gp4G

Chou, K. M. & Cheng, Y. C., May 16 2003, In : Journal of Biological Chemistry. 278, 20, p. 18289-18296 8 p.

Research output: Contribution to journalArticle

71 Scopus citations

The pentapeptide QYNAD does not block voltage-gated sodium channels

Cummins, T. R., Renganathan, M., Stys, P. K., Herzog, R. I., Scarfo, K., Horn, R., Dib-Hajj, S. D. & Waxman, S. G., Jan 28 2003, In : Neurology. 60, 2, p. 224-229 6 p.

Research output: Contribution to journalArticle

22 Scopus citations

Tight Control of Platelet-derived Growth Factor B/c-sis Expression by Interplay between the 5′-Untranslated Region Sequence and the Major Upstream Promoter

Han, B., Dong, Z. & Zhang, J. T., Nov 21 2003, In : Journal of Biological Chemistry. 278, 47, p. 46983-46993 11 p.

Research output: Contribution to journalArticle

18 Scopus citations

Two pathways for tBID-induced cytochrome c release from rat brain mitochondria: BAK- versus BAX-dependence

Brustovetsky, N., Dubinsky, J. M., Antonssont, B. & Jemmerson, R., Jan 1 2003, In : Journal of Neurochemistry. 84, 1, p. 196-207 12 p.

Research output: Contribution to journalArticle

56 Scopus citations
28 Scopus citations
2002

Activation of the midbrain periaqueductal gray induces airway smooth muscle relaxation

Haxhiu, M. A., Yamamoto, B. K., Dreshaj, I. A. & Ferguson, D. G., Jan 1 2002, In : Journal of Applied Physiology. 93, 2, p. 440-449 10 p.

Research output: Contribution to journalArticle

18 Scopus citations

A large Ca2+-dependent channel formed by recombinant ADP/ATP carrier from Neurospora crassa resembles the mitochondrial permeability transition pore

Brustovetsky, N., Tropschug, M., Heimpel, S., Heidkämper, D. & Klingenberg, M., Oct 1 2002, In : Biochemistry. 41, 39, p. 11804-11811 8 p.

Research output: Contribution to journalArticle

88 Scopus citations

Altered forebrain neurotransmitter responses to immobilization stress following 3,4-methylenedioxymethamphetamine

Matuszewich, L., Filon, M. E., Finn, D. A. & Yamamoto, B. K., Mar 1 2002, In : Neuroscience. 110, 1, p. 41-48 8 p.

Research output: Contribution to journalArticle

40 Scopus citations

Analysis of quinazoline and pyrido[2,3-d]-pyrimidine N9-C10 reversed-bridge antifolates in complex with NADP+ and Pneumocystis carinii dihydrofolate reductase

Cody, V., Galitsky, N., Luft, J. R., Pangborn, W., Queener, S. F. & Gangjee, A., Sep 1 2002, In : Acta Crystallographica Section D: Biological Crystallography. 58, 9, p. 1393-1399 7 p.

Research output: Contribution to journalArticle

20 Scopus citations

An exonucleolytic activity of human apurinic/apyrimidinic endonuclease on 3′ mispaired DNA

Chou, K. M. & Cheng, Y. C., Feb 7 2002, In : Nature. 415, 6872, p. 655-659 5 p.

Research output: Contribution to journalArticle

174 Scopus citations

An rRNA mutation identifies the apicoplast as the target for clindamycin in Toxoplasma gondii

Camps, M., Arrizabalaga, G. & Boothroyd, J., Apr 23 2002, In : Molecular Microbiology. 43, 5, p. 1309-1318 10 p.

Research output: Contribution to journalArticle

78 Scopus citations

Calcium-induced Cytochrome c release from CNS mitochondria is associated with the permeability transition and rupture of the outer membrane

Brustovetsky, N., Brustovetsky, T., Jemmerson, R. & Dubinsky, J. M., Aug 5 2002, In : Journal of Neurochemistry. 80, 2, p. 207-218 12 p.

Research output: Contribution to journalArticle

188 Scopus citations

Calcium-induced Cytochrome c release from rat brain mitochondria is altered by digitonin

Brustovetsky, N., Jemmerson, R. & Dubinsky, J. M., Oct 31 2002, In : Neuroscience Letters. 332, 2, p. 91-94 4 p.

Research output: Contribution to journalArticle

19 Scopus citations