Pharmacology & Toxicology

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Nerve growth factor, sphingomyelins, and sensitization in sensory neurons

Nicol, G. D., Oct 25 2008, In : Sheng li xue bao : [Acta physiologica Sinica]. 60, 5, p. 603-604 2 p.

Research output: Contribution to journalArticle

11 Scopus citations

Nerve growth factor/p75 neurotrophin receptor-mediated sensitization of rat sensory neurons depends on membrane cholesterol

Zhang, Y. H., Khanna, R. & Nicol, G. D., Sep 17 2013, In : Neuroscience. 248, p. 562-570 9 p.

Research output: Contribution to journalArticle

6 Scopus citations

Nerve growth factor alters microtubule targeting agent-induced neurotransmitter release but not MTA-induced neurite retraction in sensory neurons

Pittman, S. K., Gracias, N. G. & Fehrenbacher, J. C., May 1 2016, In : Experimental Neurology. 279, p. 104-115 12 p.

Research output: Contribution to journalArticle

6 Scopus citations

Nerve growth factor enhances the excitability of rat sensory neurons through activation of the atypical protein kinase C isoform, PKMζ

Zhang, Y. H., Kays, J., Hodgdon, K. E., Sacktor, T. C. & Nicol, G. D., Jan 2012, In : Journal of Neurophysiology. 107, 1, p. 315-335 21 p.

Research output: Contribution to journalArticle

24 Scopus citations

Nerve growth factor mediates a switch in intracellular signaling for PGE2-induced sensitization of sensory neurons from protein kinase A to Epac

Vasko, M. R., Habashy Malty, R., Guo, C., Duarte, D. B., Zhang, Y. & Nicol, G. D., Aug 15 2014, In : PloS one. 9, 8, e104529.

Research output: Contribution to journalArticle

12 Scopus citations

Neuroprotection against traumatic brain Injury by a peptide derived from the Collapsin Response Mediator Protein 2 (CRMP2)

Brittain, J. M., Chen, L., Wilson, S. M., Brustovetsky, T., Gao, X., Ashpole, N. M., Molosh, A. I., You, H., Hudmon, A., Shekhar, A., White, F. A., Zamponi, G. W., Brustovetsky, N., Chen, J. & Khanna, R., Oct 28 2011, In : Journal of Biological Chemistry. 286, 43, p. 37778-37792 15 p.

Research output: Contribution to journalArticle

64 Scopus citations

Neuroprotective effect of KB-r7943 against glutamate excitotoxicity is related to mild mitochondrial depolarization

Storozhevykh, T. P., Senilova, Y. E., Brustovetsky, T., Pinelis, V. G. & Brustovetsky, N., Feb 1 2010, In : Neurochemical Research. 35, 2, p. 323-335 13 p.

Research output: Contribution to journalArticle

10 Scopus citations

Neurotoxicity to dopamine neurons after the serial exposure to alcohol and methamphetamine: Protection by COX-2 antagonism

Blaker, A. L., Rodriguez, E. A. & Yamamoto, B. K., Oct 2019, In : Brain, Behavior, and Immunity. 81, p. 317-328 12 p.

Research output: Contribution to journalArticle

2 Scopus citations

Neurotoxin-induced degeneration of dopamine neurons in Caenorhabditis elegans

Nass, R., Hall, D. H., Miller, D. M. & Blakely, R. D., Mar 5 2002, In : Proceedings of the National Academy of Sciences of the United States of America. 99, 5, p. 3264-3269 6 p.

Research output: Contribution to journalArticle

247 Scopus citations
35 Scopus citations

New Drug Developments for Opportunistic Infections in Immunosuppressed Patients: Pneumocystis carnii

Queener, S. F., Nov 1 1995, In : Journal of Medicinal Chemistry. 38, 24, p. 4739-4759 21 p.

Research output: Contribution to journalArticle

73 Scopus citations

New rat model of Pneumocystis carinii infection

Bartlett, M. S., Fishman, J. A., Queener, S. F., Durkin, M. M., Jay, M. A. & Smith, J. W., 1988, In : Journal of clinical microbiology. 26, 6, p. 1100-1102 3 p.

Research output: Contribution to journalArticle

Open Access
99 Scopus citations

NF-κB: Regulation by methylation

Lu, T. & Stark, G. R., Sep 15 2015, In : Cancer Research. 75, 18, p. 3692-3695 4 p.

Research output: Contribution to journalArticle

43 Scopus citations
72 Scopus citations

Nicotine Inhibits Voltage-Dependent Sodium Channels and Sensitizes Vanilloid Receptors

Liu, L., Zhu, W., Zhang, Z. S., Yang, T., Grant, A., Oxford, G. & Simon, S. A., Apr 1 2004, In : Journal of Neurophysiology. 91, 4, p. 1482-1491 10 p.

Research output: Contribution to journalArticle

65 Scopus citations

Nitric oxide and cyclic guanosine 3',5'-monophosphate do not alter neuropeptide release from rat sensory neurons grown in culture

Dymshitz, J. & Vasko, M. R., Oct 1994, In : Neuroscience. 62, 4, p. 1279-1286 8 p.

Research output: Contribution to journalArticle

19 Scopus citations

Nonclassical 2,4-diamino-5-aryl-6-ethylpyrimidine antifolates: Activity as inhibitors of dihydrofolate reductase from Pneumocystis carinii and Toxoplasma gondii and as antitumor agents

Robson, C., Meek, M. A., Grunwaldt, J. D., Lambert, P. A., Queener, S. F., Schmidt, D. & Griffin, R. J., 1997, In : Journal of Medicinal Chemistry. 40, 19, p. 3040-3048 9 p.

Research output: Contribution to journalArticle

31 Scopus citations

Nonclassical 2,4-Diamino-6-(aminomethyl)-5,6,7,8-tetrahydroquinazoline Antifolates: Synthesis and Biological Activities

Gangjee, A., Zaveri, N., Kothare, M. & Queener, S. F., Sep 1 1995, In : Journal of Medicinal Chemistry. 38, 18, p. 3660-3668 9 p.

Research output: Contribution to journalArticle

22 Scopus citations

Nonclassical 2,4-diamino-8-deazafolate analogues as inhibitors of dihydrofolate reductases from rat liver, Pneumocystis carinii, and Toxoplasma gondii

Gangjee, A., Zhu, Y., Queener, S. F., Francom, P. & Broom, A. D., Apr 26 1996, In : Journal of Medicinal Chemistry. 39, 9, p. 1836-1845 10 p.

Research output: Contribution to journalArticle

30 Scopus citations

Noradrenaline modulates calcium channels in avian dorsal root ganglion cells through tight receptor‐channel coupling.

Forscher, P., Oxford, G. S. & Schulz, D., Oct 1 1986, In : The Journal of Physiology. 379, 1, p. 131-144 14 p.

Research output: Contribution to journalArticle

77 Scopus citations

Novel 2, 4-Diamino-5-Substituted-pyrrolo[2, 3-d]pyrimidines as Classical and Nonclassical Antifolate Inhibitors of Dihydrofolate Reductases

Gangjee, A., Mavandadi, F., Queener, S. F. & McGuire, J. J., Jun 1 1995, In : Journal of Medicinal Chemistry. 38, 12, p. 2158-2165 8 p.

Research output: Contribution to journalArticle

55 Scopus citations

Novel boron-containing, nonclassical antifolates: Synthesis and preliminary biological and structural evaluation

Reynolds, R. C., Campbell, S. R., Fairchild, R. G., Kisliuk, R. L., Micca, P. L., Queener, S. F., Riordan, J. M., Sedwick, W. D., Waud, W. R., Leung, A. K. W., Dixon, R. W., Suling, W. J. & Borhani, D. W., Jul 12 2007, In : Journal of Medicinal Chemistry. 50, 14, p. 3283-3289 7 p.

Research output: Contribution to journalArticle

51 Scopus citations
14 Scopus citations

Novel serine 176 phosphorylation of YBX1 activates NF-κB in colon cancer

Martin, M., Hua, L., Wang, B., Wei, H., Prabhu, L., Hartley, A. V., Jiang, G., Liu, Y. & Lu, T., Feb 24 2017, In : Journal of Biological Chemistry. 292, 8, p. 3433-3444 12 p.

Research output: Contribution to journalArticle

14 Scopus citations

Novel synthetic bisindolylmaleimide alkaloids inhibit STAT3 activation by binding to the SH2 domain and suppress breast xenograft tumor growth

Li, X., Ma, H., Li, L., Chen, Y., Sun, X., Dong, Z., Liu, J. Y., Zhu, W. & Zhang, J. T., May 1 2018, In : Oncogene. 37, 18, p. 2469-2480 12 p.

Research output: Contribution to journalArticle

7 Scopus citations

N-palmitoyl glycine, a novel endogenous lipid that acts as a modulator of calcium influx and nitric oxide production in sensory neurons

Rimmerman, N., Bradshaw, H. B., Hughes, H. V., Chen, J. S. C., Hu, S. S. J., McHugh, D., Vefring, E., Jahnsen, J. A., Thompson, E. L., Masuda, K., Cravatt, B. F., Burstein, S., Vasko, M. R., Prieto, A. L., O'Dell, D. K. & Walker, J. M., Jul 2008, In : Molecular pharmacology. 74, 1, p. 213-224 12 p.

Research output: Contribution to journalArticle

61 Scopus citations

NPY y 1 receptors differentially modulate gaba a and nmda receptors via divergent signal-transduction pathways to reduce excitability of amygdala neurons

Molosh, A. I., Sajdyk, T. J., Truitt, W. A., Zhu, W., Oxford, G. S. & Shekhar, A., Jun 1 2013, In : Neuropsychopharmacology. 38, 7, p. 1352-1364 13 p.

Research output: Contribution to journalArticle

32 Scopus citations

N-type calcium current, Cav2.2, is enhanced in small-diameter sensory neurons isolated from Nf1 +/- mice

Duan, J. H., Hodgdon, K. E., Hingtgen, C. M. & Nicol, G. D., Jun 13 2014, In : Neuroscience. 270, p. 192-202 11 p.

Research output: Contribution to journalArticle

10 Scopus citations

Observations of sodium channel activation gating in squid axons internally perfused with pronase or N bromoacetamide

Oxford, G. S. & Yeh, J. Z., Jan 1 1977, In : Biophysical journal. 17, 2, p. 207a

Research output: Contribution to journalArticle

2 Scopus citations

Oligomeric BAX induces mitochondrial permeability transition and complete cytochrome c release without oxidative stress

Li, T., Brustovetsky, T., Antonsson, B. & Brustovetsky, N., Nov 1 2008, In : Biochimica et Biophysica Acta - Bioenergetics. 1777, 11, p. 1409-1421 13 p.

Research output: Contribution to journalArticle

17 Scopus citations

Oligomerization domain of the multidrug resistance-associated transporter ABCG2 and its dominant inhibitory activity

Xu, J., Peng, H., Chen, Q., Liu, Y., Dong, Z. & Zhang, J. T., May 1 2007, In : Cancer Research. 67, 9, p. 4373-4381 9 p.

Research output: Contribution to journalArticle

52 Scopus citations

One-step synthesis of novel 2,4-diaminopyrimidine antifolates from bridged alicyclic ketones and cyanoguanidine

Rosowsky, A., Papoulis, A. T. & Queener, S. F., Jan 1 1999, In : Journal of Heterocyclic Chemistry. 36, 3, p. 723-728 6 p.

Research output: Contribution to journalArticle

14 Scopus citations

On the lipolytic action of parathyroid hormone (PTH) in man

Sinha, T. K., Thajchayapong, P. & Queener, S. F., Jan 1 1975, In : Clinical Research. 23, 3, p. 423A

Research output: Contribution to journalArticle

On the lipolytic action of parathyroid hormone in man

Sinha, T. K., Thajchayapong, P., Queener, S. F., Allen, D. O. & Bell, N. H., Mar 1976, In : Metabolism. 25, 3, p. 251-260 10 p.

Research output: Contribution to journalArticle

32 Scopus citations

On the lipolytic action of parathyroid hormone in man

Sinha, T. K., Thajchayapong, P. & Queener, S., Jan 1 1975, In : Clinical research. 23, 1, p. 45A

Research output: Contribution to journalArticle

Overexpression of asparagine synthetase and matrix metalloproteinase 19 confers cisplatin sensitivity in nasopharyngeal carcinoma cells

Liu, R. Y., Dong, Z., Liu, J., Zhou, L., Huang, W., Khoo, S. K., Zhang, Z., Petillo, D., Teh, B. T., Qian, C. N. & Zhang, J. T., Oct 1 2013, In : Molecular cancer therapeutics. 12, 10, p. 2157-2166 10 p.

Research output: Contribution to journalArticle

17 Scopus citations

Overexpression of BCL-x protein in primary breast cancer is associated with high tumor grade and nodal metastases

Olopade, O. I., Adeyanju, M. O., Safa, A. R., Hagos, F., Mick, R., Thompson, C. B. & Recant, W. M., 1997, In : Cancer Journal from Scientific American. 3, 4, p. 230-237 8 p.

Research output: Contribution to journalArticle

188 Scopus citations

Oxidative and conjugative metabolism of xenobiotics by livers of cattle, sheep, swine and rats.

Smith, G. S., Watkins, J. B., Thompson, T. N., Rozman, K. & Klaassen, C. D., Feb 1984, In : Journal of animal science. 58, 2, p. 386-395 10 p.

Research output: Contribution to journalArticle

54 Scopus citations

Oxidative metabolism and Ca2+ handling in isolated brain mitochondria and striatal neurons from R6/2 mice, a model of Huntington's disease

Hamilton, J., Pellman, J. J., Brustovetsky, T., Harris, R. A. & Brustovetsky, N., 2016, In : Human molecular genetics. 25, 13, p. 2762-2775 14 p.

Research output: Contribution to journalArticle

15 Scopus citations

Oxidative metabolism and Ca2+ handling in striatal mitochondria from YAC128 mice, a model of Huntington's disease

Hamilton, J., Brustovetsky, T. & Brustovetsky, N., Oct 2017, In : Neurochemistry International. 109, p. 24-33 10 p.

Research output: Contribution to journalArticle

7 Scopus citations

Oxidative metabolism in YAC128 mouse model of Huntington's disease

Hamilton, J., Pellman, J. J., Brustovetsky, T., Harris, R. A. & Brustovetsky, N., 2015, In : Human molecular genetics. 24, 17, p. 4862-4878 17 p.

Research output: Contribution to journalArticle

23 Scopus citations
19 Scopus citations

Oxidative Stress in Rats after 60 Days of Hypergalactosemia or Hyperglycemia

Otsyula, M., King, M. S., Ketcham, T. G., Sanders, R. A. & Watkins, J. B., Jan 1 2003, In : International Journal of Toxicology. 22, 6, p. 423-427 5 p.

Research output: Contribution to journalArticle

14 Scopus citations

Paclitaxel alters the evoked release of calcitonin gene-related peptide from rat sensory neurons in culture

Pittman, S. K., Gracias, N. G., Vasko, M. R. & Fehrenbacher, J. C., Mar 1 2014, In : Experimental Neurology. 253, p. 146-153 8 p.

Research output: Contribution to journalArticle

17 Scopus citations
3 Scopus citations

Pair of unusual GCN5 histone acetyltransferases and ADA2 homologues in the protozoan parasite Toxoplasma gondii

Bhatti, M. M., Livingston, M., Mullapudi, N. & Sullivan, W. J., Jan 2006, In : Eukaryotic Cell. 5, 1, p. 62-76 15 p.

Research output: Contribution to journalArticle

40 Scopus citations

Paracetamol Pharmacokinetics are Independent of Caloric Intake and Physical Activity

Yiamouyiannis, C. A., Harris, A., Sanders, R. A., Martin, B. J. & Watkins, J. B., Dec 1994, In : Drug Investigation. 8, 6, p. 361-368 8 p.

Research output: Contribution to journalArticle

3 Scopus citations

Parasite-specific eIF2 (eukaryotic initiation factor-2) kinase required for stress-induced translation control

Sullivan, W. J., Narasimhan, J., Bhatti, M. M. & Wek, R. C., Jun 1 2004, In : Biochemical Journal. 380, 2, p. 523-531 9 p.

Research output: Contribution to journalArticle

59 Scopus citations

Paroxysmal extreme pain disorder M1627K mutation in human Nav 1.7 renders DRG neurons hyperexcitable

Dib-Hajj, S. D., Estacion, M., Jarecki, B. W., Tyrrell, L., Fischer, T. Z., Lawden, M., Cummins, T. R. & Waxman, S. G., Sep 19 2008, In : Molecular Pain. 4, 37.

Research output: Contribution to journalArticle

87 Scopus citations