Pharmacology & Toxicology

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1986

Biliary excretion of organic anions in diabetic rats

Watkins, J. B. & Noda, H., Dec 1 1986, In : Journal of Pharmacology and Experimental Therapeutics. 239, 2, p. 467-473 7 p.

Research output: Contribution to journalArticle

25 Scopus citations

Dopaminergic regulation of proenkephalin-A gene expression in the basal ganglia.

Sivam, S. P., Breese, G. R., Napier, T. C., Mueller, R. A. & Hong, J. S., 1986, In : NIDA research monograph. 75, p. 389-392 4 p.

Research output: Contribution to journalArticle

9 Scopus citations

Modulation of aminopyridine block of potassium currents in squid axon

Kirsch, G. E., Yeh, J. Z. & Oxford, G. S., Jan 1 1986, In : Biophysical journal. 50, 4, p. 637-644 8 p.

Research output: Contribution to journalArticle

Open Access
33 Scopus citations

Noradrenaline modulates calcium channels in avian dorsal root ganglion cells through tight receptor‐channel coupling.

Forscher, P., Oxford, G. S. & Schulz, D., Oct 1 1986, In : The Journal of Physiology. 379, 1, p. 131-144 14 p.

Research output: Contribution to journalArticle

75 Scopus citations

Translocatable estrogen receptors in rat splenocytes

Myers, M. J., Heim, M. C., Hirsch, K. S., Queener, S. F. & Petersen, B. H., Jul 28 1986, In : Life Sciences. 39, 4, p. 313-320 8 p.

Research output: Contribution to journalArticle

10 Scopus citations

Xenobiotic biotransformation in livestock: comparison to other species commonly used in toxicity testing.

Watkins, J. B. & Klaassen, C. D., Sep 1 1986, In : Journal of animal science. 63, 3, p. 933-942 10 p.

Research output: Contribution to journalArticle

64 Scopus citations
1985

Adrenergically mediated intrapancreatic control of the glucagon response to glucopenia in the isolated rat pancreas

Hisatomi, A., Maruyama, H., Orci, L., Vasko, M. & Unger, R. H., 1985, In : Journal of Clinical Investigation. 75, 2, p. 420-426 7 p.

Research output: Contribution to journalArticle

Open Access
37 Scopus citations

Development of UDP-glucuronosyltransferase activity toward digitoxigenin-monodigitoxoside in neonatal rats

Watkins, J. B. & Klaassen, C. D., Jan 1 1985, In : Drug Metabolism and Disposition. 13, 2, p. 186-191 6 p.

Research output: Contribution to journalArticle

21 Scopus citations

Dual modulation of K channels by thyrotropin-releasing hormone in clonal pituitary cells

Dubinsky, J. M. & Oxford, G. S., Jan 1 1985, In : Proceedings of the National Academy of Sciences of the United States of America. 82, 12, p. 4282-4286 5 p.

Research output: Contribution to journalArticle

Open Access
78 Scopus citations

Effects of diabetes mellitus on renal fatty acid activation and desaturation

Clark, D. L. & Queener, S. F., Dec 15 1985, In : Biochemical Pharmacology. 34, 24, p. 4305-4310 6 p.

Research output: Contribution to journalArticle

13 Scopus citations

Interactions of monovalent cations with sodium channels in squid axon: II. Modification of pharmacological inactivation gating

Yeh, J. Z. & Oxford, G. S., Apr 1 1985, In : Journal of General Physiology. 85, 4, p. 603-620 18 p.

Research output: Contribution to journalArticle

Open Access
7 Scopus citations

Interactions of monovalent cations with sodium channels in squid axon: I. Modification of physiological inactivation gating

Oxford, G. S. & Yeh, J. Z., Apr 1 1985, In : Journal of General Physiology. 85, 4, p. 583-602 20 p.

Research output: Contribution to journalArticle

Open Access
24 Scopus citations

Modulation of calcium channels by norepinephrine in internally dialyzed avian sensory neurons

Forscher, P. & Oxford, G. S., May 1 1985, In : Journal of General Physiology. 85, 5, p. 743-763 21 p.

Research output: Contribution to journalArticle

Open Access
158 Scopus citations

Toxicological effects of gamma-irradiated sewage solids fed as seven percent of diet to sheep for four years

Smith, G. S., Hallford, D. M. & Watkins, J. B., Jan 1 1985, In : J. ANIM. SCI.. 61, 4, p. 931-941 11 p.

Research output: Contribution to journalArticle

3 Scopus citations
1984

Effect of Diethyl Ether on the Biliary Excretion of Acetaminophen

Watkins, J. B., Siegers, C. P. & Klaassen, C. D., Oct 1984, In : Proceedings of the Society for Experimental Biology and Medicine. 177, 1, p. 168-175 8 p.

Research output: Contribution to journalArticle

7 Scopus citations

Ionic currents in two strains of rat anterior pituitary tumor cells

Dubinsky, J. M. & Oxford, G. S., Mar 1 1984, In : Journal of General Physiology. 83, 3, p. 309-339 31 p.

Research output: Contribution to journalArticle

Open Access
97 Scopus citations

Oxidative and conjugative metabolism of xenobiotics by livers of cattle, sheep, swine and rats.

Smith, G. S., Watkins, J. B., Thompson, T. N., Rozman, K. & Klaassen, C. D., Feb 1984, In : Journal of animal science. 58, 2, p. 386-395 10 p.

Research output: Contribution to journalArticle

54 Scopus citations

Renal lipid desaturation in diabetes mellitus

Clark, D. L. & Queener, S. F., Jan 1 1984, In : Federation Proceedings. 43, 7, p. no. 3637

Research output: Contribution to journalArticle

1983

Changes in renal phospholipid fatty acids in diabetes mellitus: Correlation with changes in adenylate cyclase activity

Clark, D. L., Hamel, F. G. & Queener, S. F., Oct 1 1983, In : Lipids. 18, 10, p. 696-705 10 p.

Research output: Contribution to journalArticle

33 Scopus citations

Chemically-induced alteration of UDP-glucuronic acid concentration in rat liver

Watkins, J. B. & Klaassen, C. D., Jan 1 1983, In : Drug Metabolism and Disposition. 11, 1, p. 37-40 4 p.

Research output: Contribution to journalArticle

56 Scopus citations

Choleretic effect of structural analogs of valproic acid in the rat

Watkins, J. B. & Klaassen, C. D., Jan 1 1983, In : Research Communications in Chemical Pathology and Pharmacology. 39, 3, p. 355-366 12 p.

Research output: Contribution to journalArticle

3 Scopus citations

Depletion of hepatic uridine diphosphoglucuronic acid decreases the biliary excretion of drugs

Gregus, Z., Watkins, J. B., Thompson, T. N. & Klaassen, C. D., Jan 1 1983, In : Journal of Pharmacology and Experimental Therapeutics. 225, 2, p. 256-262 7 p.

Research output: Contribution to journalArticle

30 Scopus citations

Effect of gentamicin treatment on adenylate cyclase and Na+,K+-ATPase activities in renal tissues of rats

Queener, S. F., Luft, F. C. & Hamel, F. G., Jan 1 1983, In : Antimicrobial Agents and Chemotherapy. 24, 5, p. 815-818 4 p.

Research output: Contribution to journalArticle

Open Access
6 Scopus citations

Hepatic phase I and phase II biotransformations in quail and trout: Comparison to other species commonly used in toxicity testing

Gregus, Z., Watkins, J. B., Thompson, T. N., Harvey, M. J., Rozman, K. & Klaassen, C. D., Mar 15 1983, In : Toxicology and Applied Pharmacology. 67, 3, p. 430-441 12 p.

Research output: Contribution to journalArticle

95 Scopus citations

Interaction of internal anions with potassium channels of the squid giant axon

Adams, D. J. & Oxford, G. S., Oct 1 1983, In : Journal of General Physiology. 82, 4, p. 429-448 20 p.

Research output: Contribution to journalArticle

Open Access
20 Scopus citations

Minimal role of metallothionein in decreased chelator efficacy for cadmium

Waalkes, M. P., Watkins, J. B. & Klaassen, C. D., May 1983, In : Toxicology and Applied Pharmacology. 68, 3, p. 392-398 7 p.

Research output: Contribution to journalArticle

43 Scopus citations
1982

±3H-carazolol binding to rabbit renal cortical membranes

Hollingsead, P. S., Queener, S. F., Besch, H. R. & Willis, L. R., Jan 1 1982, In : Clinical research. 30, 2, p. 450A

Research output: Contribution to journalArticle

Azidoacridines as photoaffinity probes for ionic channels in excitable membranes

Oxford, G. S. & Hudson, R. A., Feb 26 1982, In : Biochemical and Biophysical Research Communications. 104, 4, p. 1579-1584 6 p.

Research output: Contribution to journalArticle

5 Scopus citations

Depletion of hepatic UDP-glucuronic acid (UDPGA) decreases the biliary excretion of drugs

Watkins, J. B., Gregus, Z., Thompson, T. B. & Klaassen, C. D., Jan 1 1982, In : Hepatology. 2, 5, p. No. 119

Research output: Contribution to journalArticle

Determination of hepatic uridine 5′-diphosphoglucuronic acid concentration by conjugation with diethylstilbestrol

Watkins, J. B. & Klaassen, C. D., Mar 1982, In : Journal of Pharmacological Methods. 7, 2, p. 145-151 7 p.

Research output: Contribution to journalArticle

33 Scopus citations

Effect of inducers and inhibitors of glucuronidation on the biliary excretion and choleretic action of valproic acid in the rat

Watkins, J. B. & Klaassen, C. D., Jan 1 1982, In : Journal of Pharmacology and Experimental Therapeutics. 220, 2, p. 305-310 6 p.

Research output: Contribution to journalArticle

45 Scopus citations

Effect of microsomal enzyme inducers on the soluble enzymes of hepatic phase II biotransformation

Thompson, T. N., Watkins, J. B., Gregus, Z. & Klaassen, C. D., Dec 1982, In : Toxicology and Applied Pharmacology. 66, 3, p. 400-408 9 p.

Research output: Contribution to journalArticle

64 Scopus citations

Induction of UDP-glucuronosyltransferase activities in Gunn, heterozygous, and Wistar rat livers by pregnenolone-16α-carbonitrile

Watkins, J. B. & Klaassen, C. D., Dec 1 1982, In : Drug Metabolism and Disposition. 10, 6, p. 590-594 5 p.

Research output: Contribution to journalArticle

44 Scopus citations

Induction studies on the functional heterogeneity of rat liver UDP-glucuronosyltransferases

Watkins, J. B., Gregus, Z., Thompson, T. N. & Klaassen, C. D., Jul 1982, In : Toxicology and Applied Pharmacology. 64, 3, p. 439-446 8 p.

Research output: Contribution to journalArticle

95 Scopus citations

Resistance of some biotransformation pathways to hepatotoxins

Watkins, J. B., Gregus, Z., Thompson, T. N. & Klaassen, C. D., Jan 1 1982, In : Federation Proceedings. 41, 5, 1 p.

Research output: Contribution to journalArticle

Resistance of some phase II biotransformation pathways to hepatotoxins

Gregus, Z., Watkins, J. B., Thompson, T. N. & Klaassen, C. D., Jan 1 1982, In : Journal of Pharmacology and Experimental Therapeutics. 222, 2, p. 471-479 9 p.

Research output: Contribution to journalArticle

42 Scopus citations

Solubilization of hormone-responsive adenylate cyclase from human renal cortex

Hamel, F. G. & Queener, S. F., Sep 30 1982, In : Biochemical and Biophysical Research Communications. 108, 2, p. 567-575 9 p.

Research output: Contribution to journalArticle

1 Scopus citations
1981

Choleretic effect of valproic acid in the rat

Watkins, J. B. & Klaassen, C. D., Jan 1 1981, In : Hepatology. 1, 4, p. 341-347 7 p.

Research output: Contribution to journalArticle

20 Scopus citations

Determination of hepatic uridine 5'-diphosphoglucuronic acid (UDPGA) by conjugation with dimethylstilbestrol (DES)

Watkins, J. B. & Klaassen, C. D., Jan 1 1981, In : Pharmacologist. 23, 3, p. No. 237

Research output: Contribution to journalArticle

Effect of inducers and inhibitors of glucuronidation on the choleretic action of valproic acid in the rat

Watkins, J. B. & Klaassen, C. D., Jan 1 1981, In : Federation Proceedings. 40, 6, 1 p.

Research output: Contribution to journalArticle

Effect of repeated oral administration of taurocholate on hepatic excretory function in the rat

Watkins, J. B. & Klaassen, C. D., Jan 1 1981, In : Journal of Pharmacology and Experimental Therapeutics. 218, 1, p. 182-187 6 p.

Research output: Contribution to journalArticle

6 Scopus citations

Internal anions modulate potassium channel gating in squid axons

Adams, D. J. & Oxford, G. S., Jan 1 1981, In : Biophysical journal. 33, 2 II, p. M-PM-C2

Research output: Contribution to journalArticle

1 Scopus citations

Permeant cations alter K channel kinetics and permeability

Oxford, G. S. & Adams, D. J., Jan 1 1981, In : Biophysical Journal. 33, 2 II, p. M-PM-C1

Research output: Contribution to journalArticle

6 Scopus citations

Pregnenoline-16α-carbonitrile (PCN), an effective inducer of hepatic phase II biotransformation in the rat

Thompson, T. N., Watkins, J. B., Gregus, Z. & Klaassen, C. D., Jan 1 1981, In : Hepatology. 1, 5, p. 63C

Research output: Contribution to journalArticle

Some kinetic and steady-state properties of sodium channels after removal of inactivation

Oxford, G. S., Jan 1 1981, In : Journal of General Physiology. 77, 1, p. 1-22 22 p.

Research output: Contribution to journalArticle

Open Access
77 Scopus citations
1980

Cardiac adenylate cyclase: Kinetics of synergistic activation by guanosine-5′-triphosphate (GTP) and glucagon

Fricke, R. F., Queener, S. F. & Clark, C. M., Jun 1980, In : Journal of Molecular and Cellular Cardiology. 12, 6, p. 595-608 14 p.

Research output: Contribution to journalArticle

1 Scopus citations

Choleretic effect of valproic acid in the rat

Watkins, J. B. & Klaassen, C. D., Jan 1 1980, In : Gastroenterology. 79, 5 II, 1 p.

Research output: Contribution to journalArticle

Comparison of the regulation of calcitonin in serum of old and young Buffalo rats

Queener, S. F., Bell, N. H., Larson, S. M., Henry, D. P. & Slatopolsky, E., Jan 1 1980, In : Journal of Endocrinology. 87, 1, p. 73-80 8 p.

Research output: Contribution to journalArticle

10 Scopus citations

Effect of repeated oral administration of taurocholate on hepatic excretory function in the rat

Watkins, J. B. & Klaasen, C. D., Jan 1 1980, In : Pharmacologist. 22, 3, 1 p.

Research output: Contribution to journalArticle