Pharmacology & Toxicology

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1982

An Analysis of GABA Receptor Changes in the Discrete Regions of Mouse Brain After Acute and Chronic Treatments with Morphine

Sivam, S. P., Nabeshima, T. & Ho, I. K., Oct 1982, In : Journal of Neurochemistry. 39, 4, p. 933-939 7 p.

Research output: Contribution to journalArticle

29 Scopus citations

A simple method for scanning electron microscope preparation of cells grown in multiwell culture plates

Safa, A. R. & Tseng, M. T., Jan 1 1982, In : Biotechnic and Histochemistry. 57, 2, p. 107-112 6 p.

Research output: Contribution to journalArticle

2 Scopus citations

Azidoacridines as photoaffinity probes for ionic channels in excitable membranes

Oxford, G. S. & Hudson, R. A., Feb 26 1982, In : Biochemical and Biophysical Research Communications. 104, 4, p. 1579-1584 6 p.

Research output: Contribution to journalArticle

5 Scopus citations

Colony forming capacity of cells derived from 7,12-dimethylbenz(a)anthracene induced mammary tumors in rat

Tseng, M. T., Safa, A. R., Halbig, T. & Bertoloir, S., Jan 1 1982, In : Journal of Cell Biology. 95, 2 II, p. no.9073

Research output: Contribution to journalArticle

Depletion of hepatic UDP-glucuronic acid (UDPGA) decreases the biliary excretion of drugs

Watkins, J. B., Gregus, Z., Thompson, T. B. & Klaassen, C. D., Jan 1 1982, In : Hepatology. 2, 5, p. No. 119

Research output: Contribution to journalArticle

Determination of hepatic uridine 5′-diphosphoglucuronic acid concentration by conjugation with diethylstilbestrol

Watkins, J. B. & Klaassen, C. D., Mar 1982, In : Journal of Pharmacological Methods. 7, 2, p. 145-151 7 p.

Research output: Contribution to journalArticle

33 Scopus citations

Development of dispositional tolerance to phencyclidine by osmotic minipump in the mouse

Toshitaka, N., Sivam, S. P., Tai, C. Y. & Ho, I. K., May 1982, In : Journal of Pharmacological Methods. 7, 3, p. 239-253 15 p.

Research output: Contribution to journalArticle

23 Scopus citations

Effect of inducers and inhibitors of glucuronidation on the biliary excretion and choleretic action of valproic acid in the rat

Watkins, J. B. & Klaassen, C. D., Jan 1 1982, In : Journal of Pharmacology and Experimental Therapeutics. 220, 2, p. 305-310 6 p.

Research output: Contribution to journalArticle

45 Scopus citations

Effect of microsomal enzyme inducers on the soluble enzymes of hepatic phase II biotransformation

Thompson, T. N., Watkins, J. B., Gregus, Z. & Klaassen, C. D., Dec 1982, In : Toxicology and Applied Pharmacology. 66, 3, p. 400-408 9 p.

Research output: Contribution to journalArticle

64 Scopus citations

Induction of UDP-glucuronosyltransferase activities in Gunn, heterozygous, and Wistar rat livers by pregnenolone-16α-carbonitrile

Watkins, J. B. & Klaassen, C. D., Dec 1 1982, In : Drug Metabolism and Disposition. 10, 6, p. 590-594 5 p.

Research output: Contribution to journalArticle

44 Scopus citations

Induction studies on the functional heterogeneity of rat liver UDP-glucuronosyltransferases

Watkins, J. B., Gregus, Z., Thompson, T. N. & Klaassen, C. D., Jul 1982, In : Toxicology and Applied Pharmacology. 64, 3, p. 439-446 8 p.

Research output: Contribution to journalArticle

95 Scopus citations

Influence of inhibitors of plant cell division and wall formation on mammary tumor cells in primary culture

Safa, A. R. & Tseng, M. T., Jan 1 1982, In : Federation Proceedings. 41, 4, p. No. 6090

Research output: Contribution to journalArticle

Influence of morphine dependence on GABA-stimulated benzodiazepine binding to mouse brain synaptic membranes

Sivam, S. P. & Ho, I. K., Apr 23 1982, In : European Journal of Pharmacology. 79, 3-4, p. 335-336 2 p.

Research output: Contribution to journalArticle

21 Scopus citations

Interaction of ouabain and propranolol in the central nervous system. Neurally-mediated effects on the cardiovascular system

Sivam, S. P., Seth, S. D., Nayar, U. & Manchanda, S. C., Jan 1 1982, In : Pharmacology. 25, 5, p. 286-293 8 p.

Research output: Contribution to journalArticle

4 Scopus citations

Normal rats trained to circle show asymmetric caudate dopamine release

Yamamoto, B. K., Lane, R. F. & Freed, C. R., Jun 21 1982, In : Life Sciences. 30, 25, p. 2155-2162 8 p.

Research output: Contribution to journalArticle

63 Scopus citations

Preparing autoradiographs of monolayer cell culture grown in polystyrene multiwell plates for scoring labeling indices

Safa, A. R. & Tseng, M. T., Jan 1 1982, In : Biotechnic and Histochemistry. 57, 5, p. 319-321 3 p.

Research output: Contribution to journalArticle

5 Scopus citations

Resistance of some biotransformation pathways to hepatotoxins

Watkins, J. B., Gregus, Z., Thompson, T. N. & Klaassen, C. D., Jan 1 1982, In : Federation Proceedings. 41, 5, 1 p.

Research output: Contribution to journalArticle

Resistance of some phase II biotransformation pathways to hepatotoxins

Gregus, Z., Watkins, J. B., Thompson, T. N. & Klaassen, C. D., Jan 1 1982, In : Journal of Pharmacology and Experimental Therapeutics. 222, 2, p. 471-479 9 p.

Research output: Contribution to journalArticle

42 Scopus citations

Solubilization of hormone-responsive adenylate cyclase from human renal cortex

Hamel, F. G. & Queener, S. F., Sep 30 1982, In : Biochemical and Biophysical Research Communications. 108, 2, p. 567-575 9 p.

Research output: Contribution to journalArticle

1 Scopus citations

The trained circling rat: A model for studying asymmetric caudate dopamine metabolism in normal animals

Yamamoto, B. K. & Freed, C. R., Jan 1 1982, In : Federation Proceedings. 41, 5, p. No. 7399

Research output: Contribution to journalArticle

The trained circling rat: A model for inducing unilateral caudate dopamine metabolism

Yamamoto, B. K. & Freed, C. R., Dec 1 1982, In : Nature. 298, 5873, p. 467-468 2 p.

Research output: Contribution to journalArticle

63 Scopus citations
1983

Changes in renal phospholipid fatty acids in diabetes mellitus: Correlation with changes in adenylate cyclase activity

Clark, D. L., Hamel, F. G. & Queener, S. F., Oct 1 1983, In : Lipids. 18, 10, p. 696-705 10 p.

Research output: Contribution to journalArticle

33 Scopus citations

Chemically-induced alteration of UDP-glucuronic acid concentration in rat liver

Watkins, J. B. & Klaassen, C. D., Jan 1 1983, In : Drug Metabolism and Disposition. 11, 1, p. 37-40 4 p.

Research output: Contribution to journalArticle

56 Scopus citations

Choleretic effect of structural analogs of valproic acid in the rat

Watkins, J. B. & Klaassen, C. D., Jan 1 1983, In : Research Communications in Chemical Pathology and Pharmacology. 39, 3, p. 355-366 12 p.

Research output: Contribution to journalArticle

3 Scopus citations

Depletion of hepatic uridine diphosphoglucuronic acid decreases the biliary excretion of drugs

Gregus, Z., Watkins, J. B., Thompson, T. N. & Klaassen, C. D., Jan 1 1983, In : Journal of Pharmacology and Experimental Therapeutics. 225, 2, p. 256-262 7 p.

Research output: Contribution to journalArticle

30 Scopus citations

Diisopropylfluorophosphate and GABA synaptic function: Effect on levels, enzymes, release and uptake in the rat striatum

Sivam, S. P., Nabeshima, T., Lim, D. K., Hoskins, B. & Ho, I. K., Dec 1 1983, In : Research Communications in Chemical Pathology and Pharmacology. 42, 1, p. 51-60 10 p.

Research output: Contribution to journalArticle

17 Scopus citations
12 Scopus citations

Effect of Acute and Chronic Cholinesterase Inhibition with Diisopropylfluorophosphate on Muscarinic, Dopamine, and GABA Receptors of the Rat Striatum

Sivam, S. P., Norris, J. C., Lim, D. K., Hoskins, B. & Ho, I. K., May 1983, In : Journal of Neurochemistry. 40, 5, p. 1414-1422 9 p.

Research output: Contribution to journalArticle

90 Scopus citations

Effect of gentamicin treatment on adenylate cyclase and Na+,K+-ATPase activities in renal tissues of rats

Queener, S. F., Luft, F. C. & Hamel, F. G., Jan 1 1983, In : Antimicrobial Agents and Chemotherapy. 24, 5, p. 815-818 4 p.

Research output: Contribution to journalArticle

Open Access
6 Scopus citations
17 Scopus citations

Gabaergic drugs, morphine and morphine tolerance: A study in relation to nociception and gastrointestinal transit in mice

Sivam, S. P. & Ho, I. K., Jun 1983, In : Neuropharmacology. 22, 6, p. 767-774 8 p.

Research output: Contribution to journalArticle

36 Scopus citations

Hepatic phase I and phase II biotransformations in quail and trout: Comparison to other species commonly used in toxicity testing

Gregus, Z., Watkins, J. B., Thompson, T. N., Harvey, M. J., Rozman, K. & Klaassen, C. D., Mar 15 1983, In : Toxicology and Applied Pharmacology. 67, 3, p. 430-441 12 p.

Research output: Contribution to journalArticle

95 Scopus citations

Improved visualization of cell nuclei in unstained cultured cells

Ballou, R. J., Safa, A. R. & Tseng, M. T., Jan 1 1983, In : Biotechnic and Histochemistry. 58, 4, p. 233-235 3 p.

Research output: Contribution to journalArticle

Influence of mitoxantrone on nucleic acid synthesis on the T‐47D breast tumor cell line

Safa, A. R., Chegini, N. & Tseng, M. T., 1983, In : Journal of Cellular Biochemistry. 22, 2, p. 111-120 10 p.

Research output: Contribution to journalArticle

15 Scopus citations

Interaction of internal anions with potassium channels of the squid giant axon

Adams, D. J. & Oxford, G. S., Oct 1 1983, In : Journal of General Physiology. 82, 4, p. 429-448 20 p.

Research output: Contribution to journalArticle

Open Access
20 Scopus citations

In vitro drug screening and individualized treatment planning for cancer patients.

Tseng, M. T. & Safa, A. R., Jan 1 1983, In : Cancer detection and prevention. 6, 3, p. 371-379 9 p.

Research output: Contribution to journalArticle

3 Scopus citations

Isolation and preparation of colonies grown on soft agar for ultrastructural investigation

Safa, A. R. & Tseng, M. T., Apr 1983, In : Journal of Microscopy. 130, 1, p. 119-122 4 p.

Research output: Contribution to journalArticle

Lactate dehydrogenase activity in cell subpopulations of 7,12-dimethylbenz(a)anthracene-induced mammary tumors

Safa, A. R. & Tseng, M. T., Mar 1983, In : Experientia. 39, 3, p. 283-285 3 p.

Research output: Contribution to journalArticle

2 Scopus citations
6 Scopus citations

Mechanism of tolerance development to pentobarbital in relation to GABA-ergic neuronal and dispositional functions in mice

Nabeshima, T., Kameyama, T., Sivam, S. & Ho, I. K., Jan 1 1983, In : Journal of Pharmacobio-Dynamics. 6, 3, p. s-61

Research output: Contribution to journalArticle

Minimal role of metallothionein in decreased chelator efficacy for cadmium

Waalkes, M. P., Watkins, J. B. & Klaassen, C. D., May 1983, In : Toxicology and Applied Pharmacology. 68, 3, p. 392-398 7 p.

Research output: Contribution to journalArticle

43 Scopus citations

Response of 7,12-Dimethylbenz(a)anthracene-Induced Rat Mammary Tumor Cells to Tamoxifen, in Vitro

Ballou, R. J., Safa, A. R. & Tseng, M. T., Jun 1983, In : Proceedings of the Society for Experimental Biology and Medicine. 173, 2, p. 256-263 8 p.

Research output: Contribution to journalArticle

3 Scopus citations

Selective maintenance of cultured epithelial cells from DMBA-induced mammary tumours by bovine colostrum supplement

Tseng, M. T., Safa, A. R. & Ballou, R., Jan 1 1983, In : Cell and Tissue Kinetics. 16, 1, p. 85-92 8 p.

Research output: Contribution to journalArticle

1 Scopus citations
3 Scopus citations
1984

Acute effects of mitoxantrone on the template activity of isolated nuclei from the T-47D human breast tumor cell line

Chegini, N., Safa, A. R. & Tseng, M. T., Jan 1984, In : Cancer Letters. 21, 3, p. 329-336 8 p.

Research output: Contribution to journalArticle

5 Scopus citations

Acute toxicity of Soman, Sarin and Tabun: Neurochemical evaluations related to cholinergic, GABAergic and dopamine systems

Sivam, S. P., Lim, D. K., Hoskins, B. & Ho, I. K., Jan 1 1984, In : Federation Proceedings. 43, 3, p. no. 1635

Research output: Contribution to journalArticle

Analgesic cross-tolerance between morphine and opioid peptides

Sivam, S. P. & Ho, I. K., Sep 1 1984, In : Psychopharmacology. 84, 1, p. 64-65 2 p.

Research output: Contribution to journalArticle

9 Scopus citations
46 Scopus citations
2 Scopus citations