Pharmacology & Toxicology

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2012

Resveratrol attenuates L-DOPA-induced hydrogen peroxide toxicity in neuronal cells

Peritore, C. S., Ho, A., Yamamoto, B. K. & Schaus, S. E., Dec 5 2012, In : NeuroReport. 23, 17, p. 989-994 6 p.

Research output: Contribution to journalArticle

12 Scopus citations

Retigeric Acid b exhibits antitumor activity through suppression of nuclear factor-κB signaling in prostate cancer cells in vitro and in vivo

Liu, Y. Q., Hu, X. Y., Lu, T., Cheng, Y. N., Young, C. Y. F., Yuan, H. Q. & Lou, H. X., May 29 2012, In : PLoS ONE. 7, 5, e38000.

Research output: Contribution to journalArticle

25 Scopus citations
7 Scopus citations

Sphingosine 1-phosphate receptor 2 antagonist JTE-013 increases the excitability of sensory neurons independently of the receptor

Li, C., Chi, X. X., Xie, W., Strong, J. A., Zhang, J. M. & Nicol, G. D., Jan 1 2012, In : Journal of Neurophysiology. 108, 5, p. 1473-1483 11 p.

Research output: Contribution to journalArticle

11 Scopus citations

Synthetic osteogenic extracellular matrix formed by coated silicon dioxide nanosprings

Hass, J. L., Garrison, E. M., Wicher, S. A., Knapp, B., Bridges, N., Mcllroy, D. N. & Arrizabalaga, G., Jan 27 2012, In : Journal of Nanobiotechnology. 10, 6.

Research output: Contribution to journalArticle

7 Scopus citations

The human Nav1.5 F1486 deletion associated with long QT syndrome leads to impaired sodium channel inactivation and reduced lidocaine sensitivity

Song, W., Xiao, Y., Chen, H., Ashpole, N. M., Piekarz, A. D., Ma, P., Hudmon, A., Cummins, T. R. & Shou, W., Oct 1 2012, In : Journal of Physiology. 590, 20, p. 5123-5139 17 p.

Research output: Contribution to journalArticle

13 Scopus citations

Toxoplasma gondii Sis1-like J-domain protein is a cytosolic chaperone associated to HSP90/HSP70 complex

Figueras, M. J., Martin, O. A., Echeverria, P. C., de Miguel, N., Naguleswaran, A., Sullivan, W. J., Corvi, M. M. & Angel, S. O., Apr 1 2012, In : International Journal of Biological Macromolecules. 50, 3, p. 725-733 9 p.

Research output: Contribution to journalArticle

8 Scopus citations

A GCN2-Like eukaryotic initiation factor 2 kinase increases the viability of extracellular toxoplasma gondii parasites

Konrad, C., Wek, R. C. & Sullivan, W. J., Nov 1 2011, In : Eukaryotic Cell. 10, 11, p. 1403-1412 10 p.

Research output: Contribution to journalArticle

28 Scopus citations

Alterations in adult behavioral responses to cocaine and dopamine transporters following juvenile exposure to methamphetamine

McFadden, L., Yamamoto, B. K. & Matuszewich, L., Jan 20 2011, In : Behavioural Brain Research. 216, 2, p. 726-730 5 p.

Research output: Contribution to journalArticle

5 Scopus citations

A novel benzodioxole-containing inhibitor of Toxoplasma gondii growth alters the parasite cell cycle

Kamau, E., Meehan, T., Lavine, M. D., Arrizabalaga, G., Wilson, G. M. & Boyle, J., Dec 1 2011, In : Antimicrobial Agents and Chemotherapy. 55, 12, p. 5438-5451 14 p.

Research output: Contribution to journalArticle

16 Scopus citations

A Toxoplasma gondii protein with homology to intracellular type Na+/H+ exchangers is important for osmoregulation and invasion

Francia, M. E., Wicher, S., Pace, D. A., Sullivan, J., Moreno, S. N. J. & Arrizabalaga, G., Jun 10 2011, In : Experimental Cell Research. 317, 10, p. 1382-1396 15 p.

Research output: Contribution to journalArticle

18 Scopus citations

Base excision repair apurinic/apyrimidinic endonucleases in apicomplexan parasite Toxoplasma gondii

Onyango, D. O., Naguleswaran, A., Delaplane, S., Reed, A., Kelley, M. R., Georgiadis, M. M. & Sullivan, W. J., May 5 2011, In : DNA Repair. 10, 5, p. 466-475 10 p.

Research output: Contribution to journalArticle

6 Scopus citations

Canonical and variant histones of protozoan parasites

Dalmasso, M. C., Sullivan, W. J. & Angel, S. O., Jun 1 2011, In : Frontiers in Bioscience. 16, 6, p. 2086-2105 20 p.

Research output: Contribution to journalArticle

13 Scopus citations

Common molecular determinants of tarantula huwentoxin-IV inhibition of Na + channel voltage sensors in domains II and IV

Xiao, Y., Jackson, J. O., Liang, S. & Cummins, T. R., Aug 5 2011, In : Journal of Biological Chemistry. 286, 31, p. 27301-27310 10 p.

Research output: Contribution to journalArticle

38 Scopus citations

Corticospinal-specific HCN expression in mouse motor cortex: I h)-dependent synaptic integration as a candidate microcircuit mechanism involved in motor control

Sheets, P. L., Suter, B. A., Kiritani, T., Savio Chan, C. S., James Surmeier, D. & Shepherd, G. M. G., Nov 1 2011, In : Journal of Neurophysiology. 106, 5, p. 2216-2231 16 p.

Research output: Contribution to journalArticle

71 Scopus citations

Critical residue that promotes protein dimerization: A story of partially exposed Phe25 in 14-3-3σ

Liu, J. Y., Li, Z., Li, H. & Zhang, J. T., Oct 24 2011, In : Journal of Chemical Information and Modeling. 51, 10, p. 2612-2625 14 p.

Research output: Contribution to journalArticle

11 Scopus citations

Crystallographic analysis reveals a novel second binding site for trimethoprim in active site double mutants of human dihydrofolate reductase

Cody, V., Pace, J., Piraino, J. & Queener, S. F., Oct 1 2011, In : Journal of Structural Biology. 176, 1, p. 52-59 8 p.

Research output: Contribution to journalArticle

11 Scopus citations

Differential gene expression of neonatal and adult DRG neurons correlates with the differential sensitization of TRPV1 responses to nerve growth factor

Zhu, W. & Oxford, G. S., Aug 18 2011, In : Neuroscience Letters. 500, 3, p. 192-196 5 p.

Research output: Contribution to journalArticle

24 Scopus citations

Direct effects of HIV-1 tat on excitability and survival of primary dorsal root ganglion neurons: Possible contribution to HIV-1-associated pain

Chi, X., Amet, T., Byrd, D., Chang, K. H., Shah, K., Hu, N., Grantham, A., Hu, S., Duan, J., Tao, F., Nicol, G. & Yu, Q., Sep 2 2011, In : PLoS ONE. 6, 9, e24412.

Research output: Contribution to journalArticle

15 Scopus citations

DNA lesion bypass polymerases and 4'-thio-β-D-arabinofuranosylcytosine (T-arac)

Chen, Y. W. & Chou, K. M., Dec 1 2011, In : International Journal of Biochemistry and Molecular Biology. 2, 4, p. 340-346 7 p.

Research output: Contribution to journalArticle

3 Scopus citations

Effect of eIF3a on response of lung cancer patients to platinum-based chemotherapy by regulating DNA repair

Yin, J. Y., Shen, J., Dong, Z. Z., Huang, Q., Zhong, M. Z., Feng, D. Y., Zhou, H. H., Zhang, J. T. & Liu, Z. Q., Jul 1 2011, In : Clinical Cancer Research. 17, 13, p. 4600-4609 10 p.

Research output: Contribution to journalArticle

49 Scopus citations

Effects of imatinib mesylate (gleevec) on human islet NF-kappaB activation and chemokine production in vitro

Mokhtari, D., Li, T., Lu, T. & Welsh, N., Sep 14 2011, In : PLoS ONE. 6, 9, e24831.

Research output: Contribution to journalArticle

16 Scopus citations

Enhancement of non-homologous end joining DNA repair capacity confers cancer cells resistance to the novel selenophene compound, D-501036

Yang, Y. N., Chou, K. M., Pan, W. Y., Chen, Y. W., Tsou, T. C., Yeh, S. C., Cheung, C. H. A., Chen, L. T. & Chang, J. Y., Oct 1 2011, In : Cancer Letters. 309, 1, p. 110-118 9 p.

Research output: Contribution to journalArticle

5 Scopus citations

Extended passaging increases the efficiency of neural differentiation from induced pluripotent stem cells

Koehler, K. R., Tropel, P., Theile, J. W., Kondo, T., Cummins, T. R., Viville, S. & Hashino, E., Aug 10 2011, In : BMC Neuroscience. 12, 82.

Research output: Contribution to journalArticle

26 Scopus citations

Further insights into the antinociceptive potential of a peptide disrupting the N-type calcium channel-CRMP-2 signaling complex

Wilson, S. M., Brittain, J. M., Piekarz, A. D., Ballard, C. J., Ripsch, M. S., Cummins, T. R., Hurley, J. H., Khanna, M., Hammes, N. M., Samuels, B. C., White, F. A. & Khanna, R., Jan 1 2011, In : Channels. 5, 5

Research output: Contribution to journalArticle

Open Access
33 Scopus citations

Hypertension incidence after tap-water implementation: A 13-year follow-up study in the arseniasis-endemic area of southwestern Taiwan

Wang, S. L., Li, W. F., Chen, C. J., Huang, Y. L., Chen, J. W., Chang, K. H., Tsai, L. Y. & Chou, K. M., Oct 1 2011, In : Science of the Total Environment. 409, 21, p. 4528-4535 8 p.

Research output: Contribution to journalArticle

11 Scopus citations

Inhibition of Navβ4 peptide-mediated resurgent sodium currents in Nav1.7 channels by carbamazepine, riluzole, and anandamide

Theile, J. W. & Cummins, T. R., Oct 1 2011, In : Molecular Pharmacology. 80, 4, p. 724-734 11 p.

Research output: Contribution to journalArticle

46 Scopus citations

Isolation and characterization of CvIV4: A pain inducing α- scorpion toxin

Rowe, A. H., Xiao, Y., Scales, J., Linse, K. D., Rowe, M. P., Cummins, T. R. & Zakon, H. H., Aug 24 2011, In : PLoS ONE. 6, 8, e23520.

Research output: Contribution to journalArticle

17 Scopus citations

KB-R7943, an inhibitor of the reverse Na +/Ca 2+ exchanger, blocks N-methyl-D-aspartate receptor and inhibits mitochondrial complex i

Brustovetsky, T., Brittain, M. K., Sheets, P. L., Cummins, T. R., Pinelis, V. & Brustovetsky, N., Jan 1 2011, In : British Journal of Pharmacology. 162, 1, p. 255-270 16 p.

Research output: Contribution to journalArticle

36 Scopus citations

Lidocaine reduces the transition to slow inactivation in Na v1.7 voltage-gated sodium channels

Sheets, P. L., Jarecki, B. W. & Cummins, T. R., Sep 1 2011, In : British Journal of Pharmacology. 164, 2 B, p. 719-730 12 p.

Research output: Contribution to journalArticle

24 Scopus citations

Methamphetamine oxidatively damages parkin and decreases the activity of 26S proteasome in vivo

Moszczynska, A. & Yamamoto, B. K., Mar 1 2011, In : Journal of Neurochemistry. 116, 6, p. 1005-1017 13 p.

Research output: Contribution to journalArticle

30 Scopus citations

Nav1.7 mutations associated with paroxysmal extreme pain disorder, but not erythromelalgia, enhance Navβ4 peptide-mediated resurgent sodium currents

Theile, J. W., Jarecki, B. W., Piekarz, A. D. & Cummins, T. R., Feb 1 2011, In : Journal of Physiology. 589, 3, p. 597-608 12 p.

Research output: Contribution to journalArticle

57 Scopus citations

Neuroprotection against traumatic brain Injury by a peptide derived from the Collapsin Response Mediator Protein 2 (CRMP2)

Brittain, J. M., Chen, L., Wilson, S. M., Brustovetsky, T., Gao, X., Ashpole, N. M., Molosh, A. I., You, H., Hudmon, A., Shekhar, A., White, F. A., Zamponi, G. W., Brustovetsky, N., Chen, J. & Khanna, R., Oct 28 2011, In : Journal of Biological Chemistry. 286, 43, p. 37778-37792 15 p.

Research output: Contribution to journalArticle

59 Scopus citations
8 Scopus citations
72 Scopus citations

Reduced expression of SynGAP, a neuronal GTPase-activating protein, enhances capsaicin-induced peripheral sensitization

Duarte, D. B., Jian-Hong, D., Nicol, G. D., Vasko, M. R. & Hingtgen, C. M., Jul 1 2011, In : Journal of Neurophysiology. 106, 1, p. 309-318 10 p.

Research output: Contribution to journalArticle

4 Scopus citations

Regions of intrinsic disorder help identify a novel nuclear localization signal in Toxoplasma gondii histone acetyltransferase TgGCN5-B

Dixon, S. E., Bhatti, M. M., Uversky, V. N., Dunker, A. K. & Sullivan, W. J., Feb 1 2011, In : Molecular and Biochemical Parasitology. 175, 2, p. 192-195 4 p.

Research output: Contribution to journalArticle

14 Scopus citations
18 Scopus citations

Regulation of phosphatase homologue of tensin protein expression by bone morphogenetic proteins in prostate epithelial cells

Jerde, T. J., Wu, Z., Theodorescu, D. & Bushman, W., Jun 1 2011, In : Prostate. 71, 8, p. 791-800 10 p.

Research output: Contribution to journalArticle

5 Scopus citations

Role of eIF3a in regulating cisplatin sensitivity and in translational control of nucleotide excision repair of nasopharyngeal carcinoma

Liu, R. Y., Dong, Z., Liu, J., Yin, J. Y., Zhou, L., Wu, X., Yang, Y., Mo, W., Huang, W., Khoo, S. K., Chen, J., Petillo, D., Teh, B. T., Qian, C. N. & Zhang, J. T., Dec 1 2011, In : Oncogene. 30, 48, p. 4814-4823 10 p.

Research output: Contribution to journalArticle

48 Scopus citations

Role of fatty acid synthase in gemcitabine and radiation resistance of pancreatic cancers

Yang, Y., Liu, H., Li, Z., Zhao, Z., Yip-Schneider, M., Fan, Q., Max Schmidt, C., Gabriela Chiorean, E., Xie, J., Cheng, L., Chen, J. H. & Zhang, J. T., Mar 7 2011, In : International Journal of Biochemistry and Molecular Biology. 2, 1, p. 89-98 10 p.

Research output: Contribution to journalArticle

48 Scopus citations

Suppression of inflammatory and neuropathic pain by uncoupling CRMP-2 from the presynaptic Ca2+ channel complex

Brittain, J. M., Duarte, D. B., Wilson, S. M., Zhu, W., Ballard, C., Johnson, P. L., Liu, N., Xiong, W., Ripsch, M. S., Wang, Y., Fehrenbacher, J. C., Fitz, S. D., Khanna, M., Park, C. K., Schmutzler, B. S., Cheon, B. M., Due, M. R., Brustovetsky, T., Ashpole, N. M., Hudmon, A. & 12 others, Meroueh, S. O., Hingtgen, C. M., Brustovetsky, N., Ji, R. R., Hurley, J. H., Jin, X., Shekhar, A., Xu, X. M., Oxford, G. S., Vasko, M. R., White, F. A. & Khanna, R., Jul 1 2011, In : Nature Medicine. 17, 7, p. 822-829 8 p.

Research output: Contribution to journalArticle

130 Scopus citations
14 Scopus citations

The repair function of the multifunctional DNA repair/redox protein APE1 is neuroprotective after ionizing radiation

Vasko, M. R., Guo, C., Thompson, E. L. & Kelley, M. R., Sep 5 2011, In : DNA Repair. 10, 9, p. 942-952 11 p.

Research output: Contribution to journalArticle

26 Scopus citations

TRPA1 receptors mediate environmental irritant-induced meningeal vasodilatation

Kunkler, P. E., Ballard, C. J., Oxford, G. S. & Hurley, J. H., Jan 1 2011, In : Pain. 152, 1, p. 38-44 7 p.

Research output: Contribution to journalArticle

85 Scopus citations

Vasodilatation in the rat dorsal hindpaw induced by activation of sensory neurons is reduced by paclitaxel

Gracias, N. G., Cummins, T. R., Kelley, M. R., Basile, D. P., Iqbal, T. & Vasko, M. R., Jan 1 2011, In : NeuroToxicology. 32, 1, p. 140-149 10 p.

Research output: Contribution to journalArticle

18 Scopus citations
2010
37 Scopus citations

4-(4-Chloro-2-methylphenoxy)-N-hydroxybutanamide (CMH) targets mRNA of the c-FLIP variants and induces apoptosis in MCF-7 human breast cancer cells

Bijangi-Vishehsaraei, K., Saadatzadeh, M. R., Huang, S., Murphy, M. P. & Safa, A. R., Sep 1 2010, In : Molecular and Cellular Biochemistry. 342, 1-2, p. 133-142 10 p.

Research output: Contribution to journalArticle

17 Scopus citations

Activation of cAMP-responsive-element-binding protein by PI3 kinase and p38 MAPK is essential for elevated expression of transforming growth factor β2 in cancer cells

Wan, Y., Yang, M., Kolattukudy, S., Stark, G. R. & Lu, T., Sep 1 2010, In : Journal of Interferon and Cytokine Research. 30, 9, p. 677-681 5 p.

Research output: Contribution to journalArticle

3 Scopus citations