Pharmacology & Toxicology

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9 Scopus citations

Cytoplasmic retraction of the amino terminus of human multidrug resistance protein 1

Chen, Q., Yang, Y., Liu, Y., Han, B. & Zhang, J. T., Jul 23 2002, In : Biochemistry. 41, 29, p. 9052-9062 11 p.

Research output: Contribution to journalArticle

18 Scopus citations
36 Scopus citations

D2 dopamine receptor activation of potassium channels in identified rat lactotrophs: Whole-cell and single-channel recording

Einhorn, L. C., Gregerson, K. A. & Oxford, G. S., Dec 1 1991, In : Journal of Neuroscience. 11, 12, p. 3727-3737 11 p.

Research output: Contribution to journalArticle

65 Scopus citations

D2 dopamine receptor activation of potassium channels is selectively decoupled by Gαi-specific GoLoco motif peptides

Webb, C. K., McCudden, C. R., Willard, F. S., Kimple, R. J., Siderovski, D. P. & Oxford, G. S., Mar 1 2005, In : Journal of Neurochemistry. 92, 6, p. 1408-1418 11 p.

Research output: Contribution to journalArticle

45 Scopus citations

D-501036, a novel selenophene-based triheterocycle derivative, exhibits potent in vitro and in vivo antitumoral activity which involves DNA damage and ataxia telangiectasia-mutated nuclear protein kinase activation

Juang, S. H., Lung, C. C., Hsu, P. C., Hsu, K. S., Li, Y. C., Hong, P. C., Shiah, H. S., Kuo, C. C., Huang, C. W., Wang, Y. C., Huang, L., Chen, T. S., Chen, S. F., Fu, K. C., Hsu, C. L., Lin, M. J., Chang, C. J., Ashendel, C. L., Chan, T. C. K., Chou, K. M. & 1 others, Chang, J. C., Jan 1 2007, In : Molecular cancer therapeutics. 6, 1, p. 193-202 10 p.

Research output: Contribution to journalArticle

42 Scopus citations

Decreased apoptosis as a mechanism for hepatomegaly in streptozotocin- induced diabetic rats

Herrman, C. E., Sanders, R. A., Klaunig, J. E., Schwarz, L. R. & Watkins, J. B., Aug 2 1999, In : Toxicological Sciences. 50, 1, p. 146-151 6 p.

Research output: Contribution to journalArticle

31 Scopus citations

Delayed calcium dysregulation in neurons requires both the NMDA receptor and the reverse Na+/Ca2+ exchanger

Brittain, M. K., Brustovetsky, T., Sheets, P. L., Brittain, J. M., Khanna, R., Cummins, T. R. & Brustovetsky, N., Apr 1 2012, In : Neurobiology of Disease. 46, 1, p. 109-117 9 p.

Research output: Contribution to journalArticle

23 Scopus citations

Deletion of mitochondrial calcium uniporter incompletely inhibits calcium uptake and induction of the permeability transition pore in brain mitochondria

Hamilton, J., Brustovetsky, T., Rysted, J. E., Lin, Z., Usachev, Y. M. & Brustovetsky, N., Oct 5 2018, In : Journal of Biological Chemistry. 293, 40, p. 15652-15663 12 p.

Research output: Contribution to journalArticle

5 Scopus citations

Demonstration of esterase activity in Pneumocystis carinii by cleavage of 4-methylumbelliferyl substrates

Durant, P. J., Bartlett, M. S., Shaw, M. M., Queener, S. F. & Smith, J. W., Sep 1 1996, In : Journal of Eukaryotic Microbiology. 43, 5, p. 45S

Research output: Contribution to journalArticle

Demonstration that cyclic adenosine 3',5' monophosphate mediates the lipolytic action of parathyroid hormone

Thajchayapong, P., Queener, S. F., McClintock, R., Allen, D. O. & Bell, N. H., Jan 1 1976, In : Unknown Journal. 8, 3, p. 190-195 6 p.

Research output: Contribution to journalArticle

4 Scopus citations

Depletion of hepatic UDP-glucuronic acid (UDPGA) decreases the biliary excretion of drugs

Watkins, J. B., Gregus, Z., Thompson, T. B. & Klaassen, C. D., Jan 1 1982, In : Hepatology. 2, 5, p. No. 119

Research output: Contribution to journalArticle

Depletion of hepatic uridine diphosphoglucuronic acid decreases the biliary excretion of drugs

Gregus, Z., Watkins, J. B., Thompson, T. N. & Klaassen, C. D., Jan 1 1983, In : Journal of Pharmacology and Experimental Therapeutics. 225, 2, p. 256-262 7 p.

Research output: Contribution to journalArticle

30 Scopus citations
52 Scopus citations
36 Scopus citations

Design, synthesis, and computational affinity prediction of ester soft drugs as inhibitors of dihydrofolate reductase from Pneumocystis carinii

Graffner-Nordberg, M., Kolmodin, K., Åqvist, J., Queener, S. F. & Hallberg, A., May 2004, In : European Journal of Pharmaceutical Sciences. 22, 1, p. 43-54 12 p.

Research output: Contribution to journalArticle

20 Scopus citations

Design, synthesis, and molecular modeling of novel pyrido[2,3-d]pyrimidine analogues as antifolates; Application of buchwald-hartwig aminations of heterocycles

Gangjee, A., Namjoshi, O. A., Raghavan, S., Queener, S. F., Kisliuk, R. L. & Cody, V., Jun 13 2013, In : Journal of Medicinal Chemistry. 56, 11, p. 4422-4441 20 p.

Research output: Contribution to journalArticle

32 Scopus citations

Design, synthesis, and x-ray crystal structure of a potent dual inhibitor of thymidylate synthase and dihydrofolate reductase as an antitumor agent

Gangjee, A., Yu, J., McGuire, J. J., Cody, V., Galitsky, N., Kisliuk, R. L. & Queener, S. F., Oct 19 2000, In : Journal of Medicinal Chemistry. 43, 21, p. 3837-3851 15 p.

Research output: Contribution to journalArticle

72 Scopus citations

Design, synthesis, and X-ray crystal structures of 2,4-diaminofuro[2,3-d]pyrimidines as multireceptor tyrosine kinase and dihydrofolate reductase inhibitors

Gangjee, A., Li, W., Lin, L., Zeng, Y., Ihnat, M., Warnke, L. A., Green, D. W., Cody, V., Pace, J. & Queener, S. F., Oct 15 2009, In : Bioorganic and Medicinal Chemistry. 17, 20, p. 7324-7336 13 p.

Research output: Contribution to journalArticle

29 Scopus citations

Design, synthesis, biological evaluation and computational investigation of novel inhibitors of dihydrofolate reductase of opportunistic pathogens

Bag, S., Tawari, N. R., Degani, M. S. & Queener, S. F., May 1 2010, In : Bioorganic and Medicinal Chemistry. 18, 9, p. 3187-3197 11 p.

Research output: Contribution to journalArticle

23 Scopus citations

Design, synthesis, computational prediction, and biological evaluation of ester soft drugs as inhibitors of dihydrofolate reductase from pneumocystis carinii

Graffner-Nordberg, M., Kolmodin, K., Åqvist, J., Queener, S. F. & Hallberg, A., Jul 19 2001, In : Journal of Medicinal Chemistry. 44, 15, p. 2391-2402 12 p.

Research output: Contribution to journalArticle

84 Scopus citations
8 Scopus citations

Design and synthesis of classical and nonclassical 6-arylthio-2,4-diamino- 5-ethylpyrrolo[2,3-d]pyrimidines as antifolates

Gangjee, A., Zeng, Y., Talreja, T., McGuire, J. J., Kisliuk, R. L. & Queener, S. F., Jun 28 2007, In : Journal of Medicinal Chemistry. 50, 13, p. 3046-3053 8 p.

Research output: Contribution to journalArticle

203 Scopus citations

Determinant of the extracellular location of the N-terminus of human multidrug-resistance-associated protein

Zhang, J. T., Jun 15 2000, In : Biochemical Journal. 348, 3, p. 597-606 10 p.

Research output: Contribution to journalArticle

11 Scopus citations

Determinants of 14-3-3σ protein dimerization and function in drug and radiation resistance

Li, Z., Peng, H., Qin, L., Qi, J., Zuo, X., Liu, J. Y. & Zhang, J. T., Nov 1 2013, In : Journal of Biological Chemistry. 288, 44, p. 31447-31457 11 p.

Research output: Contribution to journalArticle

8 Scopus citations

Determination of hepatic uridine 5'-diphosphoglucuronic acid (UDPGA) by conjugation with dimethylstilbestrol (DES)

Watkins, J. B. & Klaassen, C. D., Jan 1 1981, In : Pharmacologist. 23, 3, p. No. 237

Research output: Contribution to journalArticle

Determination of hepatic uridine 5′-diphosphoglucuronic acid concentration by conjugation with diethylstilbestrol

Watkins, J. B. & Klaassen, C. D., Mar 1982, In : Journal of Pharmacological Methods. 7, 2, p. 145-151 7 p.

Research output: Contribution to journalArticle

33 Scopus citations

Determination of mouse bladder inflammatory response to E. coli lipopolysaccharide

Jerde, T. J., Bjorling, D. E., Steinberg, H., Warner, T. & Saban, R., Jan 1 2000, In : Urological Research. 28, 4, p. 269-273 5 p.

Research output: Contribution to journalArticle

24 Scopus citations

Developmental changes in neuromuscular transmission in the rat diaphragm

Feldman, J. D., Bazzy, A. R., Cummins, T. R. & Haddad, G. G., Jan 1 1991, In : Journal of Applied Physiology. 71, 1, p. 280-286 7 p.

Research output: Contribution to journalArticle

14 Scopus citations

Development of an AlphaLISA high throughput technique to screen for small molecule inhibitors targeting protein arginine methyltransferases

Prabhu, L., Chen, L., Wei, H., Demir, Ö., Safa, A., Zeng, L., Amaro, R. E., O'Neil, B. H., Zhang, Z. Y. & Lu, T., Jan 1 2017, In : Molecular BioSystems. 13, 12, p. 2509-2520 12 p.

Research output: Contribution to journalArticle

5 Scopus citations

Development of dispositional tolerance to phencyclidine by osmotic minipump in the mouse

Toshitaka, N., Sivam, S. P., Tai, C. Y. & Ho, I. K., May 1982, In : Journal of Pharmacological Methods. 7, 3, p. 239-253 15 p.

Research output: Contribution to journalArticle

23 Scopus citations

Development of substituted pyrido[3,2-d]pyrimidines as potent and selective dihydrofolate reductase inhibitors for pneumocystis pneumonia infection

Shah, K., Queener, S., Cody, V., Pace, J. & Gangjee, A., Aug 1 2019, In : Bioorganic and Medicinal Chemistry Letters. 29, 15, p. 1874-1880 7 p.

Research output: Contribution to journalArticle

Development of UDP-glucuronosyltransferase activity toward digitoxigenin-monodigitoxoside in neonatal rats

Watkins, J. B. & Klaassen, C. D., Jan 1 1985, In : Drug Metabolism and Disposition. 13, 2, p. 186-191 6 p.

Research output: Contribution to journalArticle

21 Scopus citations

DHA2, a synthesized derivative of bisbibenzyl, exerts antitumor activity against ovarian cancer through inhibition of XIAP and Akt/mTOR pathway

Pang, Y., Si, M., Sun, B., Niu, L., Xu, X., Lu, T., Yuan, H. & Lou, H., Jul 2014, In : Food and Chemical Toxicology. 69, p. 163-174 12 p.

Research output: Contribution to journalArticle

9 Scopus citations

Diacylglycerol modulates action potential frequency in GH3 pituitary cells: correlative biochemical and electrophysiological studies

Gammon, C. M., Oxford, G. S., Allen, A. C., McCarthy, K. D. & Morell, P., Feb 13 1989, In : Brain research. 479, 2, p. 217-224 8 p.

Research output: Contribution to journalArticle

20 Scopus citations

Diagnosis of pneumocystis carinii pneumonia in aids patients by using polymerase chain reactions on serum specimens

Atzori, C., Lu, J. J., Jiang, B., Bartlett, M. S., Orlando, G., Queener, S. F., Smith, J. W., Cargnel, A. & Lee, C. H., Dec 1995, In : Journal of Infectious Diseases. 172, 6, p. 1623-1626 4 p.

Research output: Contribution to journalArticle

38 Scopus citations

Dichloroacetate alters Warburg metabolism, inhibits cell growth, and increases the X-ray sensitivity of human A549 and H1299 NSC lung cancer cells

Tan Allen, K., Chin-Sinex, H., DeLuca, T., Pomerening, J. R., Sherer, J., Watkins, J. B., Foley, J., Jesseph, J. M. & Mendonca, M. S., Dec 1 2015, In : Free Radical Biology and Medicine. 89, p. 263-273 11 p., 12539.

Research output: Contribution to journalArticle

16 Scopus citations
143 Scopus citations

Differential effects of chronic antipsychotic drug treatment on extracellular glutamate and dopamine concentrations

Yamamoto, B. K. & Cooperman, M. A., Jul 1 1994, In : Journal of Neuroscience. 14, 7, p. 4159-4166 8 p.

Research output: Contribution to journalArticle

205 Scopus citations

Differential effects of d-amphetamine on brain acetylcholine in young, adult and geriatric rats

Vasko, M. R., Domino, L. E. & Domino, E. F., Jun 1974, In : European Journal of Pharmacology. 27, 1, p. 145-147 3 p.

Research output: Contribution to journalArticle

7 Scopus citations
76 Scopus citations

Differential expression of P‐glycoprotein genes in primary rat hepatocyte culture

Lee, C. H., Bradley, G., Zhang, JT. T. & Ling, V., Nov 1993, In : Journal of cellular physiology. 157, 2, p. 392-402 11 p.

Research output: Contribution to journalArticle

75 Scopus citations

Differential gene expression of neonatal and adult DRG neurons correlates with the differential sensitization of TRPV1 responses to nerve growth factor

Zhu, W. & Oxford, G. S., Aug 18 2011, In : Neuroscience Letters. 500, 3, p. 192-196 5 p.

Research output: Contribution to journalArticle

24 Scopus citations

Differential regulation of evoked peptide release by voltage-sensitive calcium channels in rat sensory neurons

Evans, A. R., Nicol, G. D. & Vasko, M. R., Mar 18 1996, In : Brain research. 712, 2, p. 265-273 9 p.

Research output: Contribution to journalArticle

88 Scopus citations

Differential responses of Ca-activated K channels to bradykinin in sensory neurons and F-11 cells

Naruse, K., McGehee, D. S. & Oxford, G. S., Apr 6 1992, In : American Journal of Physiology - Cell Physiology. 262, 2 31-2, p. C453-C460

Research output: Contribution to journalArticle

16 Scopus citations

Differential response to doxorubicin in breast cancer subtypes simulated by a microfluidic tumor model

Ozcelikkale, A., Shin, K., Noe-Kim, V., Elzey, B. D., Dong, Z., Zhang, J. T., Kim, K., Kwon, I. C., Park, K. & Han, B., Nov 28 2017, In : Journal of Controlled Release. 266, p. 129-139 11 p.

Research output: Contribution to journalArticle

16 Scopus citations

Differential role of GDNF and NGF in the maintenance of two TTX- resistant sodium channels in adult DRG neurons

Fjell, J., Cummins, T. R., Dib-Hajj, S. D., Fried, K., Black, J. A. & Waxman, S. G., Apr 20 1999, In : Molecular Brain Research. 67, 2, p. 267-282 16 p.

Research output: Contribution to journalArticle

176 Scopus citations

Differential splicing of Pneumocystis carinii f. sp. carinii inosine 5′-monophosphate dehydrogenase pre-mRNA

Ye, D., Lee, C. H. & Queener, S. F., Jan 24 2001, In : Gene. 263, 1-2, p. 151-158 8 p.

Research output: Contribution to journalArticle

16 Scopus citations

Different roles of TM5, TM6, and ECL3 in the oligomerization and function of human ABCG2

Mo, W., Qi, J. & Zhang, J. T., May 1 2012, In : Biochemistry. 51, 17, p. 3634-3641 8 p.

Research output: Contribution to journalArticle

7 Scopus citations

Dihydropyridine receptor isoform expression in adult rat skeletal muscle

Péréon, Y., Dettbarn, C., Lu, Y., Westlund, K. N., Zhang, J. T. & Palade, P., Jul 27 1998, In : Pflugers Archiv European Journal of Physiology. 436, 3, p. 309-314 6 p.

Research output: Contribution to journalArticle

21 Scopus citations