Pharmacology & Toxicology

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2009

Local Antinociception Induced by Endothelin-1 in the Hairy Skin of the Rat's Back

Shrestha, S., Gracias, N. G., Mujenda, F., Khodorova, A., Vasko, M. R. & Strichartz, G. R., Jul 1 2009, In : Journal of Pain. 10, 7, p. 702-714 13 p.

Research output: Contribution to journalArticle

9 Scopus citations

MDMA Pretreatment Leads to Mild Chronic Unpredictable Stress-Induced Impairments in Spatial Learning

Cunningham, J. I., Raudensky, J., Tonkiss, J. & Yamamoto, B. K., Oct 1 2009, In : Behavioral Neuroscience. 123, 5, p. 1076-1084 9 p.

Research output: Contribution to journalArticle

19 Scopus citations

Rapid pain modulation with nuclear receptor ligands

Fehrenbacher, J. C., LoVerme, J., Clarke, W., Hargreaves, K. M., Piomelli, D. & Taylor, B. K., Apr 1 2009, In : Brain Research Reviews. 60, 1, p. 114-124 11 p.

Research output: Contribution to journalArticle

43 Scopus citations

Regulation of N-type voltage-gated calcium channels (Cav2.2) and transmitter release by collapsin response mediator protein-2 (CRMP-2) in sensory neurons

Chi, X. X., Schmutzler, B. S., Brittain, J. M., Wang, Y., Hingtgen, C. M., Nicol, G. D. & Khanna, R., Dec 1 2009, In : Journal of cell science. 122, 23, p. 4351-4362 12 p.

Research output: Contribution to journalArticle

85 Scopus citations

Repeated exposure to MDMA provides neuroprotection against subsequent MDMA-induced serotonin depletion in brain

Bhide, N. S., Lipton, J. W., Cunningham, J. I., Yamamoto, B. K. & Gudelsky, G. A., Aug 25 2009, In : Brain research. 1286, p. 32-41 10 p.

Research output: Contribution to journalArticle

18 Scopus citations

RNA interference in cancer: Targeting the anti-apoptotic protein c-FLIP for drug discovery

Day, T. W. & Safa, A. R., Sep 21 2009, In : Mini-Reviews in Medicinal Chemistry. 9, 6, p. 741-748 8 p.

Research output: Contribution to journalArticle

15 Scopus citations
45 Scopus citations

Role of cyclophilin D-dependent mitochondrial permeability transition in glutamate-induced calcium deregulation and excitotoxic neuronal death

Li, V., Brustovetsky, T. & Brustovetsky, N., Aug 1 2009, In : Experimental Neurology. 218, 2, p. 171-182 12 p.

Research output: Contribution to journalArticle

37 Scopus citations

Role of eIF3a in regulating cell cycle progression

Dong, Z., Liu, Z., Cui, P., Pincheira, R., Yang, Y., Liu, J. & Zhang, J. T., Jul 1 2009, In : Experimental Cell Research. 315, 11, p. 1889-1894 6 p.

Research output: Contribution to journalArticle

54 Scopus citations

Selective antifolates for chemically labeling proteins in mammalian cells

Rosa, L. P. E., Reddy, D. R., Queener, S. F. & Miller, L. W., Jun 15 2009, In : ChemBioChem. 10, 9, p. 1462-1464 3 p.

Research output: Contribution to journalArticle

1 Scopus citations

Stimulation of glutamate receptors in cultured hippocampal neurons causes Ca2+-dependent mitochondrial contraction

Brustovetsky, T., Li, V. & Brustovetsky, N., Jul 2009, In : Cell Calcium. 46, 1, p. 18-29 12 p.

Research output: Contribution to journalArticle

29 Scopus citations

The c-kit signaling pathway is involved in the development of persistent pain

Sun, Y. G., Gracias, N. G., Drobish, J. K., Vasko, M. R., Gereau, R. W. & Chen, Z. F., Jul 1 2009, In : Pain. 144, 1-2, p. 178-186 9 p.

Research output: Contribution to journalArticle

14 Scopus citations

The divalent metal transporter homologues SMF-1/2 mediate dopamine neuron sensitivity in Caenorhabditis elegans models of manganism and Parkinson disease

Settivari, R., LeVora, J. & Nass, R., Dec 18 2009, In : Journal of Biological Chemistry. 284, 51, p. 35758-35768 11 p.

Research output: Contribution to journalArticle

67 Scopus citations

The Xpc gene markedly affects cell survival in mouse bone marrow

Fischer, J. L., Kumar, M. A. S., Day, T. W., Hardy, T. M., Hamilton, S., Besch-Williford, C., Safa, A. R., Pollok, K. E. & Smith, M. L., Jul 1 2009, In : Mutagenesis. 24, 4, p. 309-316 8 p.

Research output: Contribution to journalArticle

6 Scopus citations

Toxoplasma H2A Variants Reveal Novel Insights into Nucleosome Composition and Functions for this Histone Family

Dalmasso, M. C., Onyango, D. O., Naguleswaran, A., Sullivan, W. J. & Angel, S. O., Sep 11 2009, In : Journal of molecular biology. 392, 1, p. 33-47 15 p.

Research output: Contribution to journalArticle

33 Scopus citations

Transfection of rat or mouse neurons by biolistics or electroporation

Dib-Hajj, S. D., Choi, J. S., Macala, L. J., Tyrrell, L., Black, J. A., Cummins, T. R. & Waxman, S. G., Aug 17 2009, In : Nature protocols. 4, 8, p. 1118-1126 9 p.

Research output: Contribution to journalArticle

86 Scopus citations

Understanding mechanisms and the role of differentiation in pathogenesis of Toxoplasma gondii - A Review

Sullivan, W. J., Smith, A. T. & Joyce, B. R., Mar 1 2009, In : Memorias do Instituto Oswaldo Cruz. 104, 2, p. 155-161 7 p.

Research output: Contribution to journalArticle

26 Scopus citations

Validation-based insertional mutagenesis identifies lysine demethylase FBXL11 as a negative regulator of NFκB

Lu, T., Jackson, M. W., Singhi, A. D., Kandel, E. S., Yang, M., Zhang, Y., Gudkov, A. V. & Stark, G. R., Sep 22 2009, In : Proceedings of the National Academy of Sciences of the United States of America. 106, 38, p. 16339-16344 6 p.

Research output: Contribution to journalArticle

57 Scopus citations

Voltage-clamp and current-clamp recordings from mammalian DRG neurons

Cummins, T. R., Rush, A. M., Estacion, M., Dib-Hajj, S. D. & Waxman, S. G., Aug 17 2009, In : Nature protocols. 4, 8, p. 1103-1112 10 p.

Research output: Contribution to journalArticle

62 Scopus citations
2008

A cluster of four surface antigen genes specifically expressed in bradyzoites, SAG2CDXY, plays an important role in Toxoplasma gondii persistence

Saeij, J. P. J., Arrizabalaga, G. & Boothroyd, J. C., Jun 1 2008, In : Infection and immunity. 76, 6, p. 2402-2410 9 p.

Research output: Contribution to journalArticle

45 Scopus citations

A-kinase anchoring protein mediates TRPV1 thermal hyperalgesia through PKA phosphorylation of TRPV1

Jeske, N. A., Diogenes, A., Ruparel, N. B., Fehrenbacher, J. C., Henry, M., Akopian, A. N. & Hargreaves, K. M., Sep 15 2008, In : Pain. 138, 3, p. 604-616 13 p.

Research output: Contribution to journalArticle

77 Scopus citations

Analysis of changes in the proteome of HL-60 promyeloid leukemia cells induced by the proteasome inhibitor PSI

Choi, M. R., Najafi, F., Safa, A. R. & Drexler, H. C. A., Jun 15 2008, In : Biochemical Pharmacology. 75, 12, p. 2276-2288 13 p.

Research output: Contribution to journalArticle

8 Scopus citations

A new mechanism of drug resistance in breast cancer cells: Fatty acid synthase overexpression-mediated palmitate overproduction

Liu, H., Liu, Y. & Zhang, J. T., Feb 1 2008, In : Molecular cancer therapeutics. 7, 2, p. 263-270 8 p.

Research output: Contribution to journalArticle

106 Scopus citations

Attenuation of TCDD-induced oxidative stress by 670 nm photobiomodulation in developmental chicken kidney

Lim, J., Sanders, R. A., Yeager, R. L., Millsap, D. S., Watkins, J. B., Eells, J. T. & Henshel, D. S., Sep 9 2008, In : Journal of Biochemical and Molecular Toxicology. 22, 4, p. 230-239 10 p.

Research output: Contribution to journalArticle

10 Scopus citations

Azurin-like protein blocks invasion of Toxoplasma gondii through potential interactions with parasite surface antigen SAG1

Naguleswaran, A., Fialho, A. M., Chaudhari, A., Chang, S. H., Chakrabarty, A. M. & Sullivan, W. J., Feb 1 2008, In : Antimicrobial Agents and Chemotherapy. 52, 2, p. 402-408 7 p.

Research output: Contribution to journalArticle

14 Scopus citations
36 Scopus citations

c-FLIP knockdown induces ligand-independent DR5-, FADD-, caspase-8-, and caspase-9-dependent apoptosis in breast cancer cells

Day, T. W., Huang, S. & Safa, A. R., Dec 15 2008, In : Biochemical Pharmacology. 76, 12, p. 1694-1704 11 p.

Research output: Contribution to journalArticle

60 Scopus citations

Chronic stress enhances methamphetamine-induced extracellular glutamate and excitotoxicity in the rat striatum

Tata, D. A. & Yamamoto, B. K., May 1 2008, In : Synapse. 62, 5, p. 325-336 12 p.

Research output: Contribution to journalArticle

39 Scopus citations
142 Scopus citations

Effect of cysteine mutagenesis on the function and disulfide bond formation of human ABCG2

Liu, Y., Yang, Y., Qi, J., Peng, H. & Zhang, J. T., Jul 1 2008, In : Journal of Pharmacology and Experimental Therapeutics. 326, 1, p. 33-40 8 p.

Research output: Contribution to journalArticle

30 Scopus citations

Exit from host cells by the pathogenic parasite Toxoplasma gondii does not require motility

Lavine, M. D. & Arrizabalaga, G., Jan 1 2008, In : Eukaryotic Cell. 7, 1, p. 131-140 10 p.

Research output: Contribution to journalArticle

25 Scopus citations

Gender differences in zebrafish responses to cocaine withdrawal

López Patiño, M. A., Yu, L., Yamamoto, B. K. & Zhdanova, I. V., Sep 3 2008, In : Physiology and Behavior. 95, 1-2, p. 36-47 12 p.

Research output: Contribution to journalArticle

70 Scopus citations

Human DNA polymerase η activity and translocation is regulated by phosphorylation

Chen, Y. W., Cleaver, J. E., Hatahet, Z., Honkanen, R. E., Chang, J. Y., Yen, Y. & Chou, K. M., Oct 28 2008, In : Proceedings of the National Academy of Sciences of the United States of America. 105, 43, p. 16578-16583 6 p.

Research output: Contribution to journalArticle

47 Scopus citations
86 Scopus citations

Intrinsic disorder in pathogenic and non-pathogenic microbes: Discovering and analyzing the unfoldomes of early-branching eukaryotes

Mohan, A., Sullivan, W. J., Radivojac, P., Dunker, A. K. & Uversky, V. N., Mar 28 2008, In : Molecular BioSystems. 4, 4, p. 328-340 13 p.

Research output: Contribution to journalArticle

90 Scopus citations

Ketorolac effectively inhibits ureteral contractility in vitro

Wen, C. C., Coyle, T. L. C., Jerde, T. J. & Nakada, S. Y., Apr 1 2008, In : Journal of Endourology. 22, 4, p. 739-742 4 p.

Research output: Contribution to journalArticle

7 Scopus citations

L-DOPA-induced activation of striatal p38MAPK and CREB in neonatal dopaminergic denervated rat: Relevance to self-injurious behavior

Sivam, S. P., Pugazhenthi, S., Pugazhenthi, V. & Brown, H., Feb 1 2008, In : Journal of Neuroscience Research. 86, 2, p. 339-349 11 p.

Research output: Contribution to journalArticle

5 Scopus citations

Local-circuit phenotypes of layer 5 neurons in motor-frontal cortex of YFP-H mice

Yu, J., Anderson, C. T., Kiritani, T., Sheets, P. L., Wokosin, D. L., Wood, L. & Shepherd, G. M. G., Dec 24 2008, In : Frontiers in Neural Circuits. 2, DEC, 6.

Research output: Contribution to journalArticle

42 Scopus citations

Measurements of mitochondrial pH in cultured cortical neurons clarify contribution of mitochondrial pore to the mechanism of glutamate-induced delayed Ca2+ deregulation

Bolshakov, A. P., Mikhailova, M. M., Szabadkai, G., Pinelis, V. G., Brustovetsky, N., Rizzuto, R. & Khodorov, B. I., Jun 2008, In : Cell Calcium. 43, 6, p. 602-614 13 p.

Research output: Contribution to journalArticle

37 Scopus citations
33 Scopus citations

Nerve growth factor, sphingomyelins, and sensitization in sensory neurons

Nicol, G. D., Oct 25 2008, In : Sheng li xue bao : [Acta physiologica Sinica]. 60, 5, p. 603-604 2 p.

Research output: Contribution to journalArticle

10 Scopus citations

N-palmitoyl glycine, a novel endogenous lipid that acts as a modulator of calcium influx and nitric oxide production in sensory neurons

Rimmerman, N., Bradshaw, H. B., Hughes, H. V., Chen, J. S. C., Hu, S. S. J., McHugh, D., Vefring, E., Jahnsen, J. A., Thompson, E. L., Masuda, K., Cravatt, B. F., Burstein, S., Vasko, M. R., Prieto, A. L., O'Dell, D. K. & Walker, J. M., Jul 1 2008, In : Molecular pharmacology. 74, 1, p. 213-224 12 p.

Research output: Contribution to journalArticle

60 Scopus citations

Oligomeric BAX induces mitochondrial permeability transition and complete cytochrome c release without oxidative stress

Li, T., Brustovetsky, T., Antonsson, B. & Brustovetsky, N., Nov 1 2008, In : Biochimica et Biophysica Acta - Bioenergetics. 1777, 11, p. 1409-1421 13 p.

Research output: Contribution to journalArticle

16 Scopus citations

Paroxysmal extreme pain disorder M1627K mutation in human Nav 1.7 renders DRG neurons hyperexcitable

Dib-Hajj, S. D., Estacion, M., Jarecki, B. W., Tyrrell, L., Fischer, T. Z., Lawden, M., Cummins, T. R. & Waxman, S. G., Sep 19 2008, In : Molecular Pain. 4, 37.

Research output: Contribution to journalArticle

85 Scopus citations

Paroxysmal extreme pain disorder mutations within the D3/S4-S5 linker of Nav1.7 cause moderate destabilization of fast inactivation

Jarecki, B. W., Sheets, P. L., Jackson, J. O. & Cummins, T. R., Jan 1 2008, In : Journal of Physiology. 586, 17, p. 4137-4153 17 p.

Research output: Contribution to journalArticle

58 Scopus citations

Preparation and evaluation of a high-strength biocompatible glass-ionomer cement for improved dental restoratives.

Xie, D., Zhao, J., Yang, Y., Park, J., Chu, T. M. & Zhang, J. T., Jun 2008, In : Biomedical materials (Bristol, England). 3, 2, 1 p.

Research output: Contribution to journalArticle

4 Scopus citations

Recombinant bovine dihydrofolate reductase produced by mutagenesis and nested PCR of murine dihydrofolate reductase cDNA

Cody, V., Mao, Q. & Queener, S. F., Nov 1 2008, In : Protein Expression and Purification. 62, 1, p. 104-110 7 p.

Research output: Contribution to journalArticle

2 Scopus citations

Silencing S1P1 receptors regulates collagen-V reactive lymphocyte-mediated immunobiology in the transplanted lung

Chiyo, M., Iwata, T., Webb, T. J., Vasko, M. R., Thompson, E. L., Heidler, K. M., Cummings, O. W., Yoshida, S., Fujisawa, T., Brand, D. D. & Wilkes, D. S., Mar 1 2008, In : American Journal of Transplantation. 8, 3, p. 537-546 10 p.

Research output: Contribution to journalArticle

4 Scopus citations

Spinal N-methyl-d-aspartate receptors and nociception-evoked release of primary afferent substance P

Nazarian, A., Gu, G., Gracias, N. G., Wilkinson, K., Hua, X. Y., Vasko, M. R. & Yaksh, T. L., Mar 3 2008, In : Neuroscience. 152, 1, p. 119-127 9 p.

Research output: Contribution to journalArticle

33 Scopus citations

Stretch induction of cyclooxygenase-2 expression in human urothelial cells is calcium- and protein kinase C ζ-dependent

Jerde, T. J., Mellon, W. S., Bjorling, D. E., Checura, C. M., Owusu-Ofori, K., Parrish, J. J. & Nakada, S. Y., Jan 1 2008, In : Molecular pharmacology. 73, 1, p. 18-26 9 p.

Research output: Contribution to journalArticle

8 Scopus citations