Pharmacology & Toxicology

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2006
59 Scopus citations

Low-carbohydrate diet and oxidative stress in diabetic and nondiabetic rats

Kamuren, Z. T., Sanders, R. & Watkins, J. B., Oct 20 2006, In : Journal of Biochemical and Molecular Toxicology. 20, 5, p. 259-269 11 p.

Research output: Contribution to journalArticle

6 Scopus citations

L-tyrosine contributes to (+)-3,4-methylenedioxymethamphetamine-induced serotonin depletions

Breier, J. M., Bankson, M. G. & Yamamoto, B. K., Jan 4 2006, In : Journal of Neuroscience. 26, 1, p. 290-299 10 p.

Research output: Contribution to journalArticle

33 Scopus citations
14 Scopus citations

Pair of unusual GCN5 histone acetyltransferases and ADA2 homologues in the protozoan parasite Toxoplasma gondii

Bhatti, M. M., Livingston, M., Mullapudi, N. & Sullivan, W. J., Jan 2006, In : Eukaryotic Cell. 5, 1, p. 62-76 15 p.

Research output: Contribution to journalArticle

39 Scopus citations

P-glycoprotein enhances TRAIL-triggered apoptosis in multidrug resistant cancer cells by interacting with the death receptor DR5

Park, S. J., Wu, C. H., Choi, M. R., Najafi, F., Emami, A. & Safa, A. R., Jul 28 2006, In : Biochemical Pharmacology. 72, 3, p. 293-307 15 p.

Research output: Contribution to journalArticle

25 Scopus citations
6 Scopus citations

Sensitizing hormone-refractory prostate cancer cells to drug treatment by targeting 14-3-3σ

Han, B., Xie, H., Chen, Q. & Zhang, J. T., Apr 1 2006, In : Molecular cancer therapeutics. 5, 4, p. 903-912 10 p.

Research output: Contribution to journalArticle

30 Scopus citations
63 Scopus citations

Synthesis of 2,6-diamino-5-[(2-substituted phenylamino)ethyl]pyrimidin- 4(3H)-one as inhibitors of folate metabolizing enzymes

Gangjee, A., Wang, Y., Queener, S. F. & Kisliuk, R. L., Nov 1 2006, In : Journal of Heterocyclic Chemistry. 43, 6, p. 1523-1531 9 p.

Research output: Contribution to journalArticle

3 Scopus citations

The amino terminus of the human multidrug resistance transporter ABCC1 has a U-shaped folding with a gating function

Chen, Q., Yang, Y., Li, L. & Zhang, J. T., Oct 13 2006, In : Journal of Biological Chemistry. 281, 41, p. 31152-31163 12 p.

Research output: Contribution to journalArticle

19 Scopus citations

The Role of Sodium Channels in Chronic Inflammatory and Neuropathic Pain

Amir, R., Argoff, C. E., Bennett, G. J., Cummins, T. R., Durieux, M. E., Gerner, P., Gold, M. S., Porreca, F. & Strichartz, G. R., May 1 2006, In : Journal of Pain. 7, 5 SUPPL., p. S1-S29

Research output: Contribution to journalArticle

258 Scopus citations
2005

Activation of calcium-independent phospholipase a2 (iPLA 2) in brain mitochondria and release of apoptogenic factors by BAX and truncated BID

Brustovetsky, T., Antonsson, B., Jemmerson, R., Dubinsky, J. M. & Brustovetsky, N., Aug 1 2005, In : Journal of Neurochemistry. 94, 4, p. 980-994 15 p.

Research output: Contribution to journalArticle

48 Scopus citations

Age-dependent changes in the calcium sensitivity of striatal mitochondria in mouse models of Huntington's disease

Brustovetsky, N., LaFrance, R., Purl, K. J., Brustovetsky, T., Keene, C. D., Low, W. C. & Dubinsky, J. M., Jun 1 2005, In : Journal of Neurochemistry. 93, 6, p. 1361-1370 10 p.

Research output: Contribution to journalArticle

81 Scopus citations

Age-related changes in regional brain mitochondria from Fischer 344 rats

LaFrance, R., Brustovetsky, N., Sherburne, C., DeLong, D. & Dubinsky, J. M., Jun 1 2005, In : Aging Cell. 4, 3, p. 139-145 7 p.

Research output: Contribution to journalArticle

34 Scopus citations

Bioluminescence imaging of Toxoplasma gondii infection in living mice reveals dramatic differences between strains

Saeij, J. P. J., Boyle, J. P., Grigg, M. E., Arrizabalaga, G. & Boothroyd, J. C., Feb 2005, In : Infection and immunity. 73, 2, p. 695-702 8 p.

Research output: Contribution to journalArticle

131 Scopus citations

D2 dopamine receptor activation of potassium channels is selectively decoupled by Gαi-specific GoLoco motif peptides

Webb, C. K., McCudden, C. R., Willard, F. S., Kimple, R. J., Siderovski, D. P. & Oxford, G. S., Mar 1 2005, In : Journal of Neurochemistry. 92, 6, p. 1408-1418 11 p.

Research output: Contribution to journalArticle

45 Scopus citations
53 Scopus citations
8 Scopus citations

Effects of antioxidant treatment on normal and diabetic rat retinal enzyme activities

Dene, B. A., Maritim, A. C., Sanders, R. A. & Watkins, J. B., Feb 2005, In : Journal of Ocular Pharmacology and Therapeutics. 21, 1, p. 28-35 8 p.

Research output: Contribution to journalArticle

32 Scopus citations

Expression profiling of ABC transporters in a drug-resistant breast cancer cell line using AmpArray

Liu, Y., Peng, H. & Zhang, J. T., Aug 2005, In : Molecular pharmacology. 68, 2, p. 430-438 9 p.

Research output: Contribution to journalArticle

47 Scopus citations

Externalization and recognition by macrophages of large subunit of eukaryotic translation initiation factor 3 in apoptotic cells

Nakai, Y., Shiratsuchi, A., Manaka, J., Nakayama, H., Takio, K., Zhang, J. T., Suganuma, T. & Nakanishi, Y., Sep 10 2005, In : Experimental Cell Research. 309, 1, p. 137-148 12 p.

Research output: Contribution to journalArticle

15 Scopus citations

Gain-of-function mutation in Nav1.7 in familial erythromelalgia induces bursting of sensory neurons

Dib-Hajj, S. D., Rush, A. M., Cummins, T. R., Hisama, F. M., Novella, S., Tyrrell, L., Marshall, L. & Waxman, S. G., Aug 1 2005, In : Brain. 128, 8, p. 1847-1854 8 p.

Research output: Contribution to journalArticle

312 Scopus citations

Histone acetylase GCN5 enters the nucleus via importin-α in protozoan parasite Toxoplasma gondii

Bhatti, M. M. & Sullivan, W. J., Feb 18 2005, In : Journal of Biological Chemistry. 280, 7, p. 5902-5908 7 p.

Research output: Contribution to journalArticle

33 Scopus citations

Histone-modifying complexes regulate gene expression pertinent to the differentiation of the protozoan parasite Toxoplasma gondii

Saksouk, N., Bhatti, M. M., Kieffer, S., Smith, A. T., Musset, K., Garin, J., Sullivan, W. J., Cesbron-Delauw, M. F. & Hakimi, M. A., Dec 2005, In : Molecular and cellular biology. 25, 23, p. 10301-10314 14 p.

Research output: Contribution to journalArticle

124 Scopus citations

Identification of proteins interacting with Toxoplasma SRCAP by yeast two-hybrid screening

Nallani, K. C. & Sullivan, W. J., Mar 1 2005, In : Parasitology Research. 95, 4, p. 236-242 7 p.

Research output: Contribution to journalArticle

9 Scopus citations

IMP dehydrogenase from the protozoan parasite Toxoplasma gondii

Sullivan, W. J., Dixon, S. E., Li, C., Striepen, B. & Queener, S. F., Jun 1 2005, In : Antimicrobial Agents and Chemotherapy. 49, 6, p. 2172-2179 8 p.

Research output: Contribution to journalArticle

28 Scopus citations

Influence of treatment of diabetic rats with combinations of pycnogenol, β-carotene, and α-lipoic acid on parameters of oxidative stress

Berryman, A. M., Maritim, A. C., Sanders, R. A. & Watkins, J. B., Jan 1 2005, In : Journal of Biochemical and Molecular Toxicology. 18, 6, p. 345-352 8 p.

Research output: Contribution to journalArticle

30 Scopus citations

Lack of manifestations of diazoxide/5-hydroxydecanoate-sensitive KATP channel in rat brain nonsynaptosomal mitochondria

Brustovetsky, T., Shalbuyeva, N. & Brustovetsky, N., Oct 1 2005, In : Journal of Physiology. 568, 1, p. 47-59 13 p.

Research output: Contribution to journalArticle

40 Scopus citations

Modulation of differentiation-related gene 1 expression by cell cycle blocker mimosine, revealed by proteomic analysis

Dong, Z., Arnold, R. J., Yang, Y., Park, M. H., Hrncirova, P., Mechref, Y., Novotny, M. V. & Zhang, J. T., Jul 1 2005, In : Molecular and Cellular Proteomics. 4, 7, p. 993-1001 9 p.

Research output: Contribution to journalArticle

40 Scopus citations

MYST family histone acetyltransferases in the protozoan parasite Toxoplasma gondii

Smith, A. T., Tucker-Samaras, S. D., Fairlamb, A. H. & Sullivan, W. J., Dec 2005, In : Eukaryotic Cell. 4, 12, p. 2057-2065 9 p.

Research output: Contribution to journalArticle

36 Scopus citations

Nav1.6 channels generate resurgent sodium currents in spinal sensory neurons

Cummins, T. R., Dib-Hajj, S. D., Herzog, R. I. & Waxman, S. G., Apr 11 2005, In : FEBS Letters. 579, 10, p. 2166-2170 5 p.

Research output: Contribution to journalArticle

89 Scopus citations

Pharmacological properties of neuronal TTX-resistant sodium channels and the role of a critical serine pore residue

Leffler, A., Herzog, R. I., Dib-Hajj, S. D., Waxman, S. G. & Cummins, T. R., Dec 1 2005, In : Pflugers Archiv European Journal of Physiology. 451, 3, p. 454-463 10 p.

Research output: Contribution to journalArticle

62 Scopus citations
5 Scopus citations

Regulation of expression by promoters versus internal ribosome entry site in the 5′-untranslated sequence of the human cyclin-dependent kinase inhibitor p27kip1

Liu, Z., Dong, Z., Han, B., Yang, Y., Liu, Y. & Zhang, J. T., Oct 17 2005, In : Nucleic acids research. 33, 12, p. 3763-3771 9 p.

Research output: Contribution to journalArticle

37 Scopus citations

Regulation of ribonucleotide reductase M2 expression by the upstream AUGs

Dong, Z., Liu, Y. & Zhang, J. T., Nov 3 2005, In : Nucleic acids research. 33, 8, p. 2715-2725 11 p.

Research output: Contribution to journalArticle

17 Scopus citations

Sensory neurons from Nf1 haploinsufficient mice exhibit increased excitability

Wang, Y., Nicol, G. D., Clapp, D. W. & Hingtgen, C. M., Dec 1 2005, In : Journal of Neurophysiology. 94, 6, p. 3670-3676 7 p.

Research output: Contribution to journalArticle

26 Scopus citations

Synthesis of three carbon atom bridged 2,4-diaminopyrrolo[2,3-d]- pyrimidines as nonclassical dihydrofolate reductase inhibitors

Gangjee, A., Ye, Z. & Queener, S. F., Jan 1 2005, In : Journal of Heterocyclic Chemistry. 42, 6, p. 1127-1133 7 p.

Research output: Contribution to journalArticle

6 Scopus citations

The multifunctional DNA repair/redox enzyme Ape1/Ref-1 promotes survival of neurons after oxidative stress

Vasko, M. R., Guo, C. & Kelley, M. R., Mar 2 2005, In : DNA Repair. 4, 3, p. 367-379 13 p.

Research output: Contribution to journalArticle

106 Scopus citations

The protozoan parasite Cryptosporidium parvum possesses two functionally and evolutionarily divergent replication protein A large subunits

Rider, S. D., Cai, X., Sullivan, W. J., Smith, A. T., Radke, J., White, M. & Zhu, G., Sep 9 2005, In : Journal of Biological Chemistry. 280, 36, p. 31460-31469 10 p.

Research output: Contribution to journalArticle

16 Scopus citations
55 Scopus citations
2004

A developmental switch in acute sensitization of small dorsal root ganglion (DRG) neurons to capsaicin or noxious heating by NGF

Zhu, W., Galoyan, S. M., Petruska, J. C., Oxford, G. S. & Mendell, L. M., Nov 1 2004, In : Journal of Neurophysiology. 92, 5, p. 3148-3152 5 p.

Research output: Contribution to journalArticle

56 Scopus citations
21 Scopus citations

Changes in the expression of tetrodotoxin-sensitive sodium channels within dorsal root ganglia neurons in inflammatory pain

Black, J. A., Liu, S., Tanaka, M., Cummins, T. R. & Waxman, S. G., Apr 1 2004, In : Pain. 108, 3, p. 237-247 11 p.

Research output: Contribution to journalArticle

313 Scopus citations

Characterization of Oligomeric Human Half-ABC Transporter ATP-binding Cassette G2

Xu, J., Liu, Y., Yang, Y., Bates, S. & Zhang, J. T., May 7 2004, In : Journal of Biological Chemistry. 279, 19, p. 19781-19789 9 p.

Research output: Contribution to journalArticle

221 Scopus citations
36 Scopus citations

Design, synthesis, and computational affinity prediction of ester soft drugs as inhibitors of dihydrofolate reductase from Pneumocystis carinii

Graffner-Nordberg, M., Kolmodin, K., Åqvist, J., Queener, S. F. & Hallberg, A., May 2004, In : European Journal of Pharmaceutical Sciences. 22, 1, p. 43-54 12 p.

Research output: Contribution to journalArticle

20 Scopus citations
10 Scopus citations

Electrophysiological properties of mutant Nav1.7 sodium channels in a painful inherited neuropathy

Cummins, T. R., Dib-Hajj, S. D. & Waxman, S. G., Sep 22 2004, In : Journal of Neuroscience. 24, 38, p. 8232-8236 5 p.

Research output: Contribution to journalArticle

275 Scopus citations

Evaluating metabolic syndrome in a medical physiology laboratory

Martin, B., Watkins, J. B. & Ramsey, J. W., Dec 1 2004, In : American Journal of Physiology - Advances in Physiology Education. 28, 4, p. 195-198 4 p.

Research output: Contribution to journalArticle

4 Scopus citations