Pharmacology & Toxicology

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2005

Synthesis of three carbon atom bridged 2,4-diaminopyrrolo[2,3-d]- pyrimidines as nonclassical dihydrofolate reductase inhibitors

Gangjee, A., Ye, Z. & Queener, S. F., Jan 1 2005, In : Journal of Heterocyclic Chemistry. 42, 6, p. 1127-1133 7 p.

Research output: Contribution to journalArticle

6 Scopus citations

The multifunctional DNA repair/redox enzyme Ape1/Ref-1 promotes survival of neurons after oxidative stress

Vasko, M. R., Guo, C. & Kelley, M. R., Mar 2 2005, In : DNA Repair. 4, 3, p. 367-379 13 p.

Research output: Contribution to journalArticle

107 Scopus citations

The protozoan parasite Cryptosporidium parvum possesses two functionally and evolutionarily divergent replication protein A large subunits

Rider, S. D., Cai, X., Sullivan, W. J., Smith, A. T., Radke, J., White, M. & Zhu, G., Sep 9 2005, In : Journal of Biological Chemistry. 280, 36, p. 31460-31469 10 p.

Research output: Contribution to journalArticle

16 Scopus citations
55 Scopus citations
2004

A developmental switch in acute sensitization of small dorsal root ganglion (DRG) neurons to capsaicin or noxious heating by NGF

Zhu, W., Galoyan, S. M., Petruska, J. C., Oxford, G. S. & Mendell, L. M., Nov 1 2004, In : Journal of Neurophysiology. 92, 5, p. 3148-3152 5 p.

Research output: Contribution to journalArticle

56 Scopus citations
21 Scopus citations

Changes in the expression of tetrodotoxin-sensitive sodium channels within dorsal root ganglia neurons in inflammatory pain

Black, J. A., Liu, S., Tanaka, M., Cummins, T. R. & Waxman, S. G., Apr 1 2004, In : Pain. 108, 3, p. 237-247 11 p.

Research output: Contribution to journalArticle

317 Scopus citations

Characterization of Oligomeric Human Half-ABC Transporter ATP-binding Cassette G2

Xu, J., Liu, Y., Yang, Y., Bates, S. & Zhang, J. T., May 7 2004, In : Journal of Biological Chemistry. 279, 19, p. 19781-19789 9 p.

Research output: Contribution to journalArticle

221 Scopus citations
36 Scopus citations

Design, synthesis, and computational affinity prediction of ester soft drugs as inhibitors of dihydrofolate reductase from Pneumocystis carinii

Graffner-Nordberg, M., Kolmodin, K., Åqvist, J., Queener, S. F. & Hallberg, A., May 2004, In : European Journal of Pharmaceutical Sciences. 22, 1, p. 43-54 12 p.

Research output: Contribution to journalArticle

20 Scopus citations
10 Scopus citations

Electrophysiological properties of mutant Nav1.7 sodium channels in a painful inherited neuropathy

Cummins, T. R., Dib-Hajj, S. D. & Waxman, S. G., Sep 22 2004, In : Journal of Neuroscience. 24, 38, p. 8232-8236 5 p.

Research output: Contribution to journalArticle

275 Scopus citations

Evaluating metabolic syndrome in a medical physiology laboratory

Martin, B., Watkins, J. B. & Ramsey, J. W., Dec 1 2004, In : American Journal of Physiology - Advances in Physiology Education. 28, 4, p. 195-198 4 p.

Research output: Contribution to journalArticle

4 Scopus citations

Functional selectivity of D2 receptor ligands in a Chinese hamster ovary hD2L cell line: Evidence for induction of ligand-specific receptor states

Gay, E. A., Urban, J. D., Nichols, D. E., Oxford, G. S. & Mailman, R. B., Jul 1 2004, In : Molecular pharmacology. 66, 1, p. 97-105 9 p.

Research output: Contribution to journalArticle

69 Scopus citations

High-dose methamphetamine acutely-activates the striatonigral pathway to increase striatal glutamate and mediate long-term dopamine toxicity

Mark, K. A., Soghomonian, J. J. & Yamamoto, B. K., Dec 15 2004, In : Journal of Neuroscience. 24, 50, p. 11449-11456 8 p.

Research output: Contribution to journalArticle

135 Scopus citations

Ionophore-resistant mutant of Toxoplasma gondii reveals involvement of a sodium/hydrogen exchanger in calcium regulation

Arrizabalaga, G., Ruiz, F., Moreno, S. & Boothroyd, J. C., Jun 7 2004, In : Journal of Cell Biology. 165, 5, p. 653-662 10 p.

Research output: Contribution to journalArticle

52 Scopus citations

Isolation and culture of sensory neurons from the dorsal-root ganglia of embryonic or adult rats.

Burkey, T. H., Hingtgen, C. M. & Vasko, M. R., 2004, In : Methods in molecular medicine. 99, p. 189-202 14 p.

Research output: Contribution to journalArticle

31 Scopus citations

Loss of 14-3-3σ in Prostate Cancer and Its Precursors

Cheng, L., Pan, C. X., Zhang, J. T., Zhang, S., Kinch, M. S., Li, L., Baldridge, L. A., Wade, C., Hu, Z., Koch, M. O., Ulbright, T. M. & Eble, J. N., May 1 2004, In : Clinical Cancer Research. 10, 9, p. 3064-3068 5 p.

Research output: Contribution to journalArticle

83 Scopus citations
35 Scopus citations
72 Scopus citations

Nicotine Inhibits Voltage-Dependent Sodium Channels and Sensitizes Vanilloid Receptors

Liu, L., Zhu, W., Zhang, Z. S., Yang, T., Grant, A., Oxford, G. & Simon, S. A., Apr 1 2004, In : Journal of Neurophysiology. 91, 4, p. 1482-1491 10 p.

Research output: Contribution to journalArticle

65 Scopus citations

Parasite-specific eIF2 (eukaryotic initiation factor-2) kinase required for stress-induced translation control

Sullivan, W. J., Narasimhan, J., Bhatti, M. M. & Wek, R. C., Jun 1 2004, In : Biochemical Journal. 380, 2, p. 523-531 9 p.

Research output: Contribution to journalArticle

59 Scopus citations
66 Scopus citations

RNA Helicase A in the MEF1 Transcription Factor Complex Up-regulates the MDR1 Gene in Multidrug-resistant Cancer Cells

Zhong, X. & Safa, A. R., Apr 23 2004, In : Journal of Biological Chemistry. 279, 17, p. 17134-17141 8 p.

Research output: Contribution to journalArticle

32 Scopus citations

Role of eIF3 p170 in controlling synthesis of ribonucleotide reductase M2 and cell growth

Dong, Z., Liu, L. H., Han, B., Pincheira, R. & Zhang, J. T., May 6 2004, In : Oncogene. 23, 21, p. 3790-3801 12 p.

Research output: Contribution to journalArticle

84 Scopus citations

Role of external pallidal segment in primate parkinsonism: Comparison of the effects of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-induced parkinsionism and lesions of the external pallidal segment

Soares, J., Kliem, M. A., Betarbet, R., Greenamyre, J. T., Yamamoto, B. & Wichmann, T., Jul 21 2004, In : Journal of Neuroscience. 24, 29, p. 6417-6426 10 p.

Research output: Contribution to journalArticle

132 Scopus citations

Secreted transforming growth factor β2 activates NF-κB, blocks apoptosis, and is essential for the survival of some tumor cells

Lu, T., Burdelya, L. G., Swiatkowski, S. M., Boiko, A. D., Howe, P. H., Stark, G. R. & Gudkov, A. V., May 4 2004, In : Proceedings of the National Academy of Sciences of the United States of America. 101, 18, p. 7112-7117 6 p.

Research output: Contribution to journalArticle

87 Scopus citations
28 Scopus citations
38 Scopus citations

Taxol induces caspase-10-dependent apoptosis

Park, S. J., Wu, C. H., Gordon, J. D., Zhong, X., Emami, A. & Safa, A. R., Dec 3 2004, In : Journal of Biological Chemistry. 279, 49, p. 51057-51067 11 p.

Research output: Contribution to journalArticle

170 Scopus citations

The Biology and Pharmacology of Calcium Channel α2-δ Proteins Pfizer satellite symposium to the 2003 Society for Neuroscience Meeting Sheraton New Orleans Hotel New Orleans, LA November 10, 2003

Taylor, C. P., Catterall, W. A., Hofmann, F., Luo, Z. D., Wustrow, D. J., Vasko, M., Field, M. & Baron, S., 2004, In : CNS Drug Reviews. 10, 2, p. 183-188 6 p.

Research output: Contribution to journalArticle

95 Scopus citations
44 Scopus citations
2003

7-Methyl trimethoprim analogues as inhibitors of the folate metabolizing enzymes

Gangjee, A., Lin, X. & Queener, S. F., Jan 1 2003, In : Journal of Heterocyclic Chemistry. 40, 3, p. 507-512 6 p.

Research output: Contribution to journalArticle

4 Scopus citations

Activation of epidermal vanilloid receptor-1 induces release of proinflammatory mediators in human keratinocytes

Southall, M. D., Li, T., Gharibova, L. S., Pei, Y., Nicol, G. D. & Travers, J. B., Jan 1 2003, In : Journal of Pharmacology and Experimental Therapeutics. 304, 1, p. 217-222 6 p.

Research output: Contribution to journalArticle

239 Scopus citations

ATP augments peptide release from rat sensory neurons in culture through activation of P2Y receptors

Huang, H., Wu, X., Nicol, G. D., Meller, S. & Vasko, M. R., Sep 1 2003, In : Journal of Pharmacology and Experimental Therapeutics. 306, 3, p. 1137-1144 8 p.

Research output: Contribution to journalArticle

35 Scopus citations

Calmodulin binds to the C terminus of sodium channels Nav1.4 and Navl.6 and differentially modulates their functional properties

Herzog, R. I., Liu, C., Waxman, S. G. & Cummins, T. R., Sep 10 2003, In : Journal of Neuroscience. 23, 23, p. 8261-8270 10 p.

Research output: Contribution to journalArticle

Open Access
118 Scopus citations

Effects of pycnogenol treatment on oxidative stress in streptozotocin-induced diabetic rats

Maritim, A., Dene, B. A., Sanders, R. A. & Watkins, J. B., Jul 18 2003, In : Journal of Biochemical and Molecular Toxicology. 17, 3, p. 193-199 7 p.

Research output: Contribution to journalArticle

75 Scopus citations

Effects of α-lipoic acid on biomarkers of oxidative stress in streptozotocin-induced diabetic rats

Maritim, A. C., Sanders, R. A. & Watkins, J. B., May 1 2003, In : Journal of Nutritional Biochemistry. 14, 5, p. 288-294 7 p.

Research output: Contribution to journalArticle

193 Scopus citations

EIF3 p170, a mediator of mimosine effect on protein synthesis and cell cycle progression

Dong, Z. & Zhang, J. T., Sep 1 2003, In : Molecular Biology of the Cell. 14, 9, p. 3942-3951 10 p.

Research output: Contribution to journalArticle

80 Scopus citations
36 Scopus citations
15 Scopus citations

Molecular cloning and characterization of an SRCAP chromatin remodeling homologue in Toxoplasma gondii

Sullivan, W. J., Monroy, M. A., Bohne, W., Nallani, K. C., Chrivia, J., Yaciuk, P., Smith, C. K. & Queener, S. F., May 1 2003, In : Parasitology Research. 90, 1, p. 1-8 8 p.

Research output: Contribution to journalArticle

21 Scopus citations

Oxidative Stress in Rats after 60 Days of Hypergalactosemia or Hyperglycemia

Otsyula, M., King, M. S., Ketcham, T. G., Sanders, R. A. & Watkins, J. B., Jan 1 2003, In : International Journal of Toxicology. 22, 6, p. 423-427 5 p.

Research output: Contribution to journalArticle

14 Scopus citations
280 Scopus citations

Prostaglandin E2 inhibits the potassium current in sensory neurons from hyperalgesic Kv1.1 knockout mice

Jiang, X., Zhang, Y. H., Clark, J. D., Tempel, B. L. & Nicol, G. D., Jun 18 2003, In : Neuroscience. 119, 1, p. 65-72 8 p.

Research output: Contribution to journalArticle

17 Scopus citations

Protein kinase C phosphorylation sensitizes but does not activate the capsaicin receptor transient receptor potential vanilloid 1 (TRPV1)

Bhave, G., Hu, H. J., Glauner, K. S., Zhu, W., Wang, H., Brasier, D. J., Oxford, G. S. & Gereau IV, R. W., Oct 14 2003, In : Proceedings of the National Academy of Sciences of the United States of America. 100, 21, p. 12480-12485 6 p.

Research output: Contribution to journalArticle

304 Scopus citations

Regulation of constitutive expression of mouse PTEN by the 5′-untranslated region

Han, B., Dong, Z., Liu, Y., Chen, Q., Hashimoto, K. & Zhang, J. T., Aug 14 2003, In : Oncogene. 22, 34, p. 5325-5337 13 p.

Research output: Contribution to journalArticle

52 Scopus citations

Synaptic and membrane properties of neurons in the dorsomedial hypothalamus

Bailey, T. W., Nicol, G. D., Schild, J. H. & DiMicco, J. A., Sep 26 2003, In : Brain research. 985, 2, p. 150-162 13 p.

Research output: Contribution to journalArticle

16 Scopus citations
55 Scopus citations

Synthesis and DHFR inhibitory activity of a series of 6-substituted-2,4-diaminothieno[2,3-d]pyrimidines

Donkor, I. O., Li, H. & Queener, S. F., Jun 1 2003, In : European Journal of Medicinal Chemistry. 38, 6, p. 605-611 7 p.

Research output: Contribution to journalArticle

44 Scopus citations