Pharmacology & Toxicology

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1 Citation (Scopus)

Effects of PERK eIF2α Kinase Inhibitor against Toxoplasma gondii

Augusto, L., Martynowicz, J., Staschke, K. A., Wek, R. & Sullivan, W., Nov 1 2018, In : Antimicrobial Agents and Chemotherapy. 62, 11

Research output: Contribution to journalArticle

Eukaryotic Initiation Factor-2
Toxoplasma
Parasites
Phosphotransferases
Endoplasmic Reticulum Stress
72 Citations (Scopus)

Effects of piperine on antioxidant pathways in tissues from normal and streptozotocin-induced diabetic rats

Rauscher, F. M., Sanders, R. A. & Watkins, J. B., Jan 1 2000, In : Journal of Biochemical and Molecular Toxicology. 14, 6, p. 329-334 6 p.

Research output: Contribution to journalArticle

piperine
Streptozocin
Glutathione Disulfide
Rats
Medical problems
73 Citations (Scopus)

Effects of pycnogenol treatment on oxidative stress in streptozotocin-induced diabetic rats

Maritim, A., Dene, B. A., Sanders, R. A. & Watkins, J. B., Jul 18 2003, In : Journal of Biochemical and Molecular Toxicology. 17, 3, p. 193-199 7 p.

Research output: Contribution to journalArticle

Oxidative stress
Streptozocin
Rats
Oxidative Stress
Body Weight
121 Citations (Scopus)

Effects of Quercetin on antioxidant defense in streptozotocin-induced diabetic rats

Sanders, R. A., Rauscher, F. M. & Watkins, J. B., Jun 19 2001, In : Journal of Biochemical and Molecular Toxicology. 15, 3, p. 143-149 7 p.

Research output: Contribution to journalArticle

Quercetin
Streptozocin
Rats
Antioxidants
Glutathione Disulfide
22 Citations (Scopus)

Effects of sphingosine stereoisomers on P-glycoprotein phosphorylation and vinblastine accumulation in multidrug-resistant MCF-7 cells

Sachs, C. W., Balks, L. M., Mascarella, S. W., Safa, A. R., Lewin, A. H., Loomis, C., Carroll, F. I., Bell, R. M. & Fine, R. L., Jan 1 1996, In : Biochemical Pharmacology. 52, 4, p. 603-612 10 p.

Research output: Contribution to journalArticle

Phosphorylation
Stereoisomerism
Sphingosine
Vinblastine
MCF-7 Cells
9 Citations (Scopus)

Effects of stress and MDMA on hippocampal gene expression

Weber, G. F., Johnson, B. N., Yamamoto, B. K. & Gudelsky, G. A., Feb 5 2014, In : BioMed research international. 2014, 141396.

Research output: Contribution to journalArticle

N-Methyl-3,4-methylenedioxyamphetamine
Gene expression
Gene Expression
Serotonin
Rats
45 Citations (Scopus)
Methamphetamine
Nucleus Accumbens
Dopamine
Dopamine Plasma Membrane Transport Proteins
Norepinephrine Plasma Membrane Transport Proteins

Effects of tamoxifen on cell subpopulations of 7,12-dimethylbenz(α)anthracene (DMBA)-induced rat mammary tumor in primary culture

Ballou, R. J., Safa, A. R. & Tseng, M. T., Jan 1 1981, In : Anatomical Record. 199, 3, p. 17A

Research output: Contribution to journalArticle

tamoxifen
9,10-Dimethyl-1,2-benzanthracene
mammary neoplasms (animal)
Tamoxifen
Breast Neoplasms
14 Citations (Scopus)

Effects of the dipolar form of phloretin on potassium conductance in squid giant axons

Strichartz, G. R., Oxford, G. S. & Ramon, F., Jan 1 1980, In : Biophysical Journal. 31, 2, p. 229-246 18 p.

Research output: Contribution to journalArticle

Open Access
Phloretin
Decapodiformes
Axons
Potassium
Perfusion
186 Citations (Scopus)

Effects of α-lipoic acid on biomarkers of oxidative stress in streptozotocin-induced diabetic rats

Maritim, A. C., Sanders, R. A. & Watkins, J. B., May 1 2003, In : Journal of Nutritional Biochemistry. 14, 5, p. 288-294 7 p.

Research output: Contribution to journalArticle

Thioctic Acid
Oxidative stress
Biomarkers
Streptozocin
Rats
24 Citations (Scopus)

Effects of β-carotene on oxidative stress in normal and diabetic rats

Maritim, A., Dene, B. A., Sanders, R. A. & Watkins, J. B., Oct 23 2002, In : Journal of Biochemical and Molecular Toxicology. 16, 4, p. 203-208 6 p.

Research output: Contribution to journalArticle

Oxidative stress
Carotenoids
Rats
Oxidative Stress
Medical problems
18 Citations (Scopus)

Efficacy of Intermittent Dosage of 8-Aminoquinolines for Therapy or Prophylaxis of Pneumocystis Pneumonia in Rats

Queener, S. F., Dean, R. A., Bartlett, M. S., Milhous, W. K., Berman, J. D., Ellis, W. Y. & Smith, J. W., Apr 1 1992, In : Journal of Infectious Diseases. 165, 4, p. 764-768 5 p.

Research output: Contribution to journalArticle

Pneumocystis Pneumonia
Primaquine
Therapeutics
Sulfamethoxazole Drug Combination Trimethoprim
8-aminoquinoline
28 Citations (Scopus)

eGFP expression under UCHL1 promoter genetically labels corticospinal motor neurons and a subpopulation of degeneration-resistant spinal motor neurons in an ALS mouse model

Yasvoina, M. V., Genç, B., Jara, J. H., Sheets, P. L., Quinlan, K. A., Milosevic, A., Shepherd, G. M. G., Heckman, C. J. & Özdinler, P. H., May 10 2013, In : Journal of Neuroscience. 33, 18, p. 7890-7904 15 p.

Research output: Contribution to journalArticle

Motor Neurons
Dendrites
Motor Cortex
Neurons
Genetic Hybridization
19 Citations (Scopus)

EIF3i promotes colon oncogenesis by regulating COX-2 protein synthesis and β-catenin activation

Qi, J., Dong, Z., Liu, J. & Zhang, J. T., Aug 7 2014, In : Oncogene. 33, 32, p. 4156-4163 8 p.

Research output: Contribution to journalArticle

Catenins
Cyclooxygenase 2
Colon
Carcinogenesis
Eukaryotic Initiation Factors
80 Citations (Scopus)

EIF3 p170, a mediator of mimosine effect on protein synthesis and cell cycle progression

Dong, Z. & Zhang, J. T., Sep 1 2003, In : Molecular Biology of the Cell. 14, 9, p. 3942-3951 10 p.

Research output: Contribution to journalArticle

Eukaryotic Initiation Factor-3
Mimosine
Cell Cycle Proteins
Protein Biosynthesis
Tubulin
39 Citations (Scopus)

Electrical currents associated with nucleotide transport by the reconstituted mitochondrial ADP/ATP carrier

Brustovetsky, N., Becker, A., Klingenberg, M. & Bamberg, E., Jan 23 1996, In : Proceedings of the National Academy of Sciences of the United States of America. 93, 2, p. 664-668 5 p.

Research output: Contribution to journalArticle

ATP Translocases Mitochondrial ADP
Adenosine Diphosphate
Nucleotides
Adenosine Triphosphate
Photolysis
9 Citations (Scopus)
Chlorides
Cell Line
Bile Ducts
Baths
Glutamic Acid
267 Citations (Scopus)

Electrophysiological properties of mutant Nav1.7 sodium channels in a painful inherited neuropathy

Cummins, T. R., Dib-Hajj, S. D. & Waxman, S. G., Sep 22 2004, In : Journal of Neuroscience. 24, 38, p. 8232-8236 5 p.

Research output: Contribution to journalArticle

Erythromelalgia
Sodium Channels
Spinal Ganglia
Mutation
Neurons
15 Citations (Scopus)

Elongator protein 3 (Elp3) lysine acetyltransferase is a tail-anchored mitochondrial protein in toxoplasma gondii

Stilger, K. L. & Sullivan, W. J., Aug 30 2013, In : Journal of Biological Chemistry. 288, 35, p. 25318-25329 12 p.

Research output: Contribution to journalArticle

Acetyltransferases
Mitochondrial Proteins
Toxoplasma
Lysine
Mitochondria
1 Citation (Scopus)

Elp3 and RlmN: A tale of two mitochondrial tail-anchored radical SAM enzymes in Toxoplasma gondii

Padgett, L. R., Lentini, J. M., Holmes, M. J., Stilger, K. L., Fu, D. & Sullivan, W., Jan 1 2018, In : PLoS One. 13, 1, e0189688.

Research output: Contribution to journalArticle

S-Adenosylmethionine
Toxoplasma
Toxoplasma gondii
S-adenosylmethionine
Tail
19 Citations (Scopus)

Emerging targets for glioblastoma stem cell therapy

Safa, A., Saadatzadeh, M. R., Cohen-Gadol, A., Pollok, K. & Bijangi-Vishehsaraei, K., 2016, In : Journal of Biomedical Research. 30, 1, p. 19-31 13 p.

Research output: Contribution to journalArticle

Glioblastoma
Cell- and Tissue-Based Therapy
Stem cells
Stem Cells
Tumors
44 Citations (Scopus)

Endothelin-1 enhances capsaicin-induced peptide release and cGMP accumulation in cultures of rat sensory neurons

Dymshitz, J. & Vasko, M. R., Feb 14 1994, In : Neuroscience Letters. 167, 1-2, p. 128-132 5 p.

Research output: Contribution to journalArticle

Capsaicin
Endothelin-1
Sensory Receptor Cells
Peptides
Calcitonin Gene-Related Peptide
1 Citation (Scopus)
Corpus Striatum
Induced Pluripotent Stem Cells
Superoxides
Energy Metabolism
Neurons
2 Citations (Scopus)

Enhanced brain distribution of modified aspartoacylase

Poddar, N. K., Zano, S., Natarajan, R., Yamamoto, B. & Viola, R. E., Nov 1 2014, In : Molecular Genetics and Metabolism. 113, 3, p. 219-224 6 p.

Research output: Contribution to journalArticle

Brain
Enzymes
Canavan Disease
Enzyme Replacement Therapy
Tissue Distribution
71 Citations (Scopus)

Enhancement by prostaglandin E2 of bradykinin activation of embryonic rat sensory neurones.

Nicol, G. D. & Cui, M., Nov 1 1994, In : The Journal of Physiology. 480, 3, p. 485-492 8 p.

Research output: Contribution to journalArticle

Bradykinin
Sensory Receptor Cells
Dinoprostone
Action Potentials
Membrane Potentials
48 Citations (Scopus)

Enhancement of 3,4-methylenedioxymethamphetamine neurotoxicity by the energy inhibitor malonate

Nixdorf, W. L., Burrows, K. B., Gudelsky, G. A. & Yamamoto, B. K., Apr 25 2001, In : Journal of Neurochemistry. 77, 2, p. 647-654 8 p.

Research output: Contribution to journalArticle

N-Methyl-3,4-methylenedioxyamphetamine
Dopamine
Serotonin
Tissue
Neurons
6 Citations (Scopus)

Enhancement of bovine pancreatic ribonuclease activity by mercaptoethanol

Watkins, J. B. & Benz, F. W., Jan 1 1978, In : Science. 199, 4333, p. 1084-1087 4 p.

Research output: Contribution to journalArticle

Pancreatic Ribonuclease
Mercaptoethanol
Ribonucleases
Cyclic CMP
Cytidine
5 Citations (Scopus)

Enhancement of non-homologous end joining DNA repair capacity confers cancer cells resistance to the novel selenophene compound, D-501036

Yang, Y. N., Chou, K. M., Pan, W. Y., Chen, Y. W., Tsou, T. C., Yeh, S. C., Cheung, C. H. A., Chen, L. T. & Chang, J. Y., Oct 1 2011, In : Cancer Letters. 309, 1, p. 110-118 9 p.

Research output: Contribution to journalArticle

DNA Repair
Drug Resistance
DNA
KB Cells
Neoplasms

Enhancement of sodium channel inactivation by octanol and decanol

Swenson, R. P., Oxford, G. S. & Narahashi, T., Jan 1 1978, In : Biophysical Journal. 21, 3, p. 41a

Research output: Contribution to journalArticle

Octanols
Sodium Channels
114 Citations (Scopus)

Enhancing Hematopoietic Stem Cell Transplantation Efficacy by Mitigating Oxygen Shock

Mantel, C. R., O'Leary, H. A., Chitteti, B. R., Huang, X., Cooper, S., Hangoc, G., Brustovetsky, N., Srour, E. F., Lee, M. R., Messina-Graham, S., Haas, D. M., Falah, N., Kapur, R., Pelus, L. M., Bardeesy, N., Fitamant, J., Ivan, M., Kim, K. S. & Broxmeyer, H. E., Jun 18 2015, In : Cell. 161, 7, p. 1553-1565 13 p.

Research output: Contribution to journalArticle

Hematopoietic Stem Cell Transplantation
Hematopoietic Stem Cells
Stem cells
Shock
Oxygen
17 Citations (Scopus)

Enterocyte-like differentiation of the Caco-2 intestinal cell line is associated with increases in AP-1 protein binding

Ding, Q., Dong, Z. & Evers, B. M., Dec 11 1998, In : Life Sciences. 64, 3, p. 175-182 8 p.

Research output: Contribution to journalArticle

Caco-2 Cells
Enterocytes
Transcription Factor AP-1
Protein Binding
Cells
7 Citations (Scopus)

Epac activation sensitizes rat sensory neurons through activation of Ras

Shariati, B., Thompson, E. L., Nicol, G. & Vasko, M., Jan 1 2016, In : Molecular and Cellular Neuroscience. 70, p. 54-67 14 p.

Research output: Contribution to journalArticle

Sensory Receptor Cells
Action Potentials
Calcitonin Gene-Related Peptide
Perfusion
Capsaicin
244 Citations (Scopus)

Essential features of the P-glycoprotein pharmacophore as defined by a series of reserpine analogs that modulate multidrug resistance

Pearce, H. L., Safa, A. R., Bach, N. J., Winter, M. A., Cirtain, M. C. & Beck, W. T., Jan 1 1989, In : Proceedings of the National Academy of Sciences of the United States of America. 86, 13, p. 5128-5132 5 p.

Research output: Contribution to journalArticle

Open Access
Reserpine
Multiple Drug Resistance
P-Glycoprotein
Vinblastine
Nitrogen
23 Citations (Scopus)

Etoposide induces protein kinase Cδ- and caspase-3-dependent apoptosis in neuroblastoma cancer cells

Day, T. W., Wu, C. H. & Safa, A. R., Sep 1 2009, In : Molecular Pharmacology. 76, 3, p. 632-640 9 p.

Research output: Contribution to journalArticle

Etoposide
Neuroblastoma
Caspase 3
Protein Kinase C
Caspase 8
4 Citations (Scopus)

Evaluating metabolic syndrome in a medical physiology laboratory

Martin, B., Watkins, J. B. & Ramsey, J. W., Dec 1 2004, In : American Journal of Physiology - Advances in Physiology Education. 28, 4, p. 195-198 4 p.

Research output: Contribution to journalArticle

Cholesterol
Meals
Triglycerides
Diet
Dietary Carbohydrates
21 Citations (Scopus)

Evaluation of a Bayesian method for predicting vancomycin dosing

Burton, M. E., Gentle, D. L. & Vasko, M. R., Jan 1 1989, In : DICP, Annals of Pharmacotherapy. 23, 4, p. 294-300 7 p.

Research output: Contribution to journalArticle

Bayes Theorem
Vancomycin
Population
Serum
Pharmacokinetics
3 Citations (Scopus)

Evaluation of ATM Kinase Inhibitor KU-55933 as Potential Anti-Toxoplasma gondii Agent

Munera López, J., Ganuza, A., Bogado, S. S., Muñoz, D., Ruiz, D. M., Sullivan, W., Vanagas, L. & Angel, S. O., Jan 1 2019, In : Frontiers in cellular and infection microbiology. 9, 1 p.

Research output: Contribution to journalArticle

Open Access
Toxoplasma
Phosphotransferases
Parasites
Phosphatidylinositol 3-Kinase
Camptothecin
Open Access
Methamphetamine
Microglia
Prefrontal Cortex
Macrophages
RNA Sequence Analysis
28 Citations (Scopus)

Evaluation of potent inhibitors of dihydrofolate reductase in a culture model for growth of Pneumocystis carinii

Bartlett, M. S., Shaw, M., Navaran, P., Smith, J. W. & Queener, S. F., Jan 1 1995, In : Antimicrobial Agents and Chemotherapy. 39, 11, p. 2436-2441 6 p.

Research output: Contribution to journalArticle

Open Access
Folic Acid Antagonists
Pneumocystis carinii
Trimetrexate
Tetrahydrofolate Dehydrogenase
Growth
2 Citations (Scopus)

Evaluation of sulfa drugs against recombinant Pneumocystis carinii dihydropteroate synthetase and in vivo

Hong, Y. L., Hossler, P., Bartlett, M., Queener, S., Smith, J. & Meshnick, S., Sep 1 1996, In : Journal of Eukaryotic Microbiology. 43, 5, p. 40S

Research output: Contribution to journalArticle

Sulfanilamides
Sulfamethoxypyridazine
Dihydropteroate Synthase
Pneumocystis
Pneumocystis carinii
20 Citations (Scopus)

Evaluation of ureteric contraction: A comparison among ring, spiral-cut and longitudinal segments

Jerde, T. J., Saban, R. & Nakada, S. Y., Apr 13 1999, In : BJU International. 83, 1, p. 95-100 6 p.

Research output: Contribution to journalArticle

Carbachol
Electric Stimulation
Suspensions
Ureter
Neurotransmitter Agents
2 Citations (Scopus)

Evaluation of urothelial stretch-induced cyclooxygenase-2 expression in a mouse ureteral obstruction model

Sterrett, S. P., Wilkinson, E. R., Jerde, T. J., Mellon, W. S. & Nakada, S. Y., Mar 1 2009, In : Journal of Endourology. 23, 3, p. 541-544 4 p.

Research output: Contribution to journalArticle

Ureteral Obstruction
Cyclooxygenase 2
Prostaglandins
Cyclooxygenase 1
Ligation
15 Citations (Scopus)

Evaluation of urothelial stretch-induced cyclooxygenase-2 expression in novel human cell culture and porcine in vivo ureteral obstruction models

Jerde, T. J., Mellon, W. S., Bjorling, D. E. & Nakada, S. Y., Jun 1 2006, In : Journal of Pharmacology and Experimental Therapeutics. 317, 3, p. 965-972 8 p.

Research output: Contribution to journalArticle

Ureteral Obstruction
Cyclooxygenase 2
Swine
Cell Culture Techniques
RNA Stability
45 Citations (Scopus)
N-Methyl-3,4-methylenedioxyamphetamine
Serotonin
Nitric Oxide
Brain
Dopamine
25 Citations (Scopus)

Exit from host cells by the pathogenic parasite Toxoplasma gondii does not require motility

Lavine, M. D. & Arrizabalaga, G., Jan 1 2008, In : Eukaryotic Cell. 7, 1, p. 131-140 10 p.

Research output: Contribution to journalArticle

Toxoplasma
Toxoplasma gondii
Parasites
parasites
actin
5 Citations (Scopus)

Expansion of prostate epithelial progenitor cells after inflammation of the mouse prostate

Wang, L., Zoetemelk, M., Chitteti, B. R., Ratliff, T. L., Myers, J. D., Srour, E. F., Broxmeyer, H. & Jerde, T. J., Jun 15 2015, In : American Journal of Physiology - Renal Physiology. 308, 12, p. F1421-F1430

Research output: Contribution to journalArticle

Prostate
Stem Cells
Epithelial Cells
Inflammation
Hyperplasia
13 Citations (Scopus)

Exposure of rats to inhalational anesthetics alters the hepatobiliary clearance of cholephilic xenobiotics

Watkins, J. B., Jan 1 1989, In : Journal of Pharmacology and Experimental Therapeutics. 250, 2, p. 421-427 7 p.

Research output: Contribution to journalArticle

Xenobiotics
Anesthetics
Digoxin
Halothane
Acetaminophen
27 Citations (Scopus)

Expression of DNA translesion synthesis polymerase η in head and neck squamous cell cancer predicts resistance to gemcitabine and cisplatin-based chemotherapy

Zhou, W., Chen, Y. W., Liu, X., Chu, P., Loria, S., Wang, Y., Yen, Y. & Chou, K. M., Dec 20 2013, In : PLoS ONE. 8, 12, e83978.

Research output: Contribution to journalArticle

gemcitabine
Squamous Cell Neoplasms
cisplatin
Chemotherapy
Head and Neck Neoplasms
17 Citations (Scopus)

Expression of sphingosine 1-phosphate receptors in the rat dorsal root ganglia and defined single isolated sensory neurons

Kays, J. S., Li, C. & Nicol, G. D., Sep 1 2012, In : Physiological Genomics. 44, 18, p. 889-901 13 p.

Research output: Contribution to journalArticle

Lysosphingolipid Receptors
Spinal Ganglia
Sensory Receptor Cells
Neurons
Messenger RNA
9 Citations (Scopus)

Expression of the essential kinase PFCDPK1 from plasmodium falciparum in toxoplasma gondii facilitates the discovery of novel antimalarial drugs

Gaji, R. Y., Checkley, L., Reese, M. L., Ferdig, M. T. & Arrizabalaga, G., May 2014, In : Antimicrobial Agents and Chemotherapy. 58, 5, p. 2598-2607 10 p.

Research output: Contribution to journalArticle

Toxoplasma
Antimalarials
Plasmodium falciparum
Phosphotransferases
Merozoites