Biochemistry & Molecular Biology

Fingerprint The fingerprint is based on mining the text of the scientific documents related to the associated persons. Based on that an index of weighted terms is created, which defines the key subjects of research unit

Proteins Medicine & Life Sciences
Phosphorylation Chemical Compounds
Genes Medicine & Life Sciences
Alcoholism Medicine & Life Sciences
Glycogen Synthase Medicine & Life Sciences
3-Methyl-2-Oxobutanoate Dehydrogenase (Lipoamide) Medicine & Life Sciences
Liver Medicine & Life Sciences
Phosphotransferases Medicine & Life Sciences

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Profiles

No photo of Karen Cowden Dahl

Karen Cowden Dahl

Person: Academic

20012018
No photo of Anna De Paoli-Roach

Anna De Paoli-Roach

Person: Academic

19742017
No photo of X. Dong

X. Dong

Person: Academic

20002020

NIH Grants 1975 2021

Autophagy
Lipid Metabolism
Non-alcoholic Fatty Liver Disease
Alcohols
Liver
Lafora Disease
Glycogen
Glycogen Synthase
Therapeutics
Pharmaceutical Chemistry
Genomics
Psychiatry
National Institute of Mental Health (U.S.)
Therapeutic Human Experimentation
Genome-Wide Association Study

Publications 1971 2019

A high throughput substrate binding assay reveals hexachlorophene as an inhibitor of the ER-resident HSP70 chaperone GRP78

Ambrose, A. J., Zerio, C. J., Sivinski, J., Schmidlin, C. J., Shi, T., Ross, A. B., Widrick, K. J., Johnson, S., Zhang, D. D. & Chapman, E., Jul 15 2019, In : Bioorganic and Medicinal Chemistry Letters. 29, 14, p. 1689-1693 5 p.

Research output: Contribution to journalArticle

Hexachlorophene
HSP70 Heat-Shock Proteins
Assays
Throughput
Substrates

Analysis of whole genome-transcriptomic organization in brain to identify genes associated with alcoholism

Kapoor, M., Wang, J. C., Farris, S. P., Liu, Y., McClintick, J., Gupta, I., Meyers, J. L., Bertelsen, S., Chao, M., Nurnberger, J., Tischfield, J., Harari, O., Zeran, L., Hesselbrock, V., Bauer, L., Raj, T., Porjesz, B., Agrawal, A., Foroud, T., Edenberg, H. & 2 othersMayfield, R. D. & Goate, A., Dec 1 2019, In : Translational psychiatry. 9, 1, 89.

Research output: Contribution to journalArticle

Alcoholism
Genome
Alcohol Drinking
Brain
Genes

A novel aldh1a1 inhibitor targets cells with stem cell characteristics in ovarian cancer

Nwani, N. G., Condello, S., Wang, Y., Swetzig, W. M., Barber, E., Hurley, T. & Matei, D., Apr 1 2019, In : Cancers. 11, 4, 502.

Research output: Contribution to journalArticle

Open Access
Ovarian Neoplasms
Stem Cells
Aldehyde Dehydrogenase
DNA Damage
Cell Proliferation