Cardiothoracic Surgery

Publications 1968 2019

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2008
114 Citations (Scopus)

VEGF is critical for stem cell-mediated cardioprotection and a crucial paracrine factor for defining the age threshold in adult and neonatal stem cell function

Markel, T. A., Wang, Y., Herrmann, J. L., Crisostomo, P. R., Wang, M., Novotny, N. M., Herring, C. M., Tan, J., Lahm, T. & Meldrum, D. R., Dec 2008, In : American Journal of Physiology - Heart and Circulatory Physiology. 295, 6

Research output: Contribution to journalArticle

Adult Stem Cells
Age Factors
Vascular Endothelial Growth Factor A
Stem Cells
Mesenchymal Stromal Cells
7 Citations (Scopus)

Ventricular assist device implantation in the pediatric population: Does pump size selection and associated hemodynamics impact outcomes?

Husain, S. A., Wallis, G., Fricker, F. J., Bleiweis, M. S., Staples, E. D., Klodell, C. T., Brown, J. & Turrentine, M., Sep 2008, In : ASAIO Journal. 54, 5, p. 474-478 5 p.

Research output: Contribution to journalArticle

Pediatrics
Heart-Assist Devices
Hemodynamics
Blood
Pumps
2007
32 Citations (Scopus)

Activation of individual tumor necrosis factor receptors differentially affects stem cell growth factor and cytokine production

Markel, T. A., Crisostomo, P. R., Wang, M., Herring, C. M. & Meldrum, D. R., Oct 2007, In : American Journal of Physiology - Gastrointestinal and Liver Physiology. 293, 4

Research output: Contribution to journalArticle

Stem Cell Factor
Tumor Necrosis Factor Receptors
Intercellular Signaling Peptides and Proteins
Vascular Endothelial Growth Factor A
Cytokines
6 Citations (Scopus)

A novel biomarker for the detection of esophageal adenocarcinoma

Hammoud, Z. T., Badve, S., Saxena, R., Kesler, K., Rieger, K., Malkas, L. H. & Hickey, R. J., Jan 2007, In : Journal of Thoracic and Cardiovascular Surgery. 133, 1, p. 82-87 6 p.

Research output: Contribution to journalArticle

Proliferating Cell Nuclear Antigen
Adenocarcinoma
Biomarkers
Neoplasms
Staining and Labeling
1 Citation (Scopus)

A woman with facial papules and pulmonary nodules

Erickson, B. W., Cripe, L., Rieger, K., Cummings, O. & Wilkes, D., Jul 2007, In : Respiration. 74, 4, p. 471-474 4 p.

Research output: Contribution to journalArticle

Lymphomatoid Granulomatosis
X Ray Computed Tomography
Bronchoscopy
Exanthema
Lung Diseases
31 Citations (Scopus)

Deficiency of TNFR1 protects myocardium through SOCS3 and IL-6 but not p38 MAPK or IL-1β

Wang, M., Markel, T., Crisostomo, P., Herring, C., Meldrum, K. K., Lillemoe, K. D. & Meldrum, D. R., Apr 2007, In : American Journal of Physiology - Heart and Circulatory Physiology. 292, 4

Research output: Contribution to journalArticle

Receptors, Tumor Necrosis Factor, Type I
p38 Mitogen-Activated Protein Kinases
Interleukin-1
Interleukin-6
Myocardium
9 Citations (Scopus)

Diagnosis of Esophageal Adenocarcinoma by Serum Proteomic Pattern

Hammoud, Z. T., Dobrolecki, L., Kesler, K., Rahmani, E., Rieger, K., Malkas, L. H. & Hickey, R. J., Aug 2007, In : Annals of Thoracic Surgery. 84, 2, p. 384-392 9 p.

Research output: Contribution to journalArticle

Proteomics
Adenocarcinoma
Serum
Biomarkers
Lasers
50 Citations (Scopus)

Endogenous estrogen attenuates pulmonary artery vasoreactivity and acute hypoxic pulmonary vasoconstriction: The effects of sex and menstrual cycle

Lahm, T., Patel, K. M., Crisostomo, P. R., Markel, T. A., Wang, M., Herring, C. & Meldrum, D. R., Sep 2007, In : American Journal of Physiology - Endocrinology and Metabolism. 293, 3

Research output: Contribution to journalArticle

Menstrual Cycle
Vasoconstriction
Pulmonary Artery
Estrogens
Vasoconstrictor Agents
48 Citations (Scopus)

Endothelial STAT3 plays a critical role in generalized myocardial proinflammatory and proapoptotic signaling

Wang, M., Zhang, W., Crisostomo, P., Markel, T., Meldrum, K. K., Fu, X. Y. & Meldrum, D. R., Oct 2007, In : American Journal of Physiology - Heart and Circulatory Physiology. 293, 4

Research output: Contribution to journalArticle

Endothelial Cells
Knockout Mice
Reperfusion
Ischemia
Apoptosis
66 Citations (Scopus)

Fontan Operation: A Comparison of Lateral Tunnel with Extracardiac Conduit

Fiore, A. C., Turrentine, M., Rodefeld, M., Vijay, P., Schwartz, T. L., Virgo, K. S., Fischer, L. K. & Brown, J., Feb 2007, In : Annals of Thoracic Surgery. 83, 2, p. 622-630 9 p.

Research output: Contribution to journalArticle

Fontan Procedure
montirelin
Nervous System
Heterotaxy Syndrome
Hypoplastic Left Heart Syndrome
87 Citations (Scopus)

Gender differences in injury induced mesenchymal stem cell apoptosis and VEGF, TNF, IL-6 expression: Role of the 55 kDa TNF receptor (TNFR1)

Crisostomo, P. R., Wang, M., Herring, C. M., Markel, T. A., Meldrum, K. K., Lillemoe, K. D. & Meldrum, D. R., Jan 2007, In : Journal of Molecular and Cellular Cardiology. 42, 1, p. 142-149 8 p.

Research output: Contribution to journalArticle

Tumor Necrosis Factor Receptors
Mesenchymal Stromal Cells
Vascular Endothelial Growth Factor A
Interleukin-6
Apoptosis
33 Citations (Scopus)

Incidence of and Risk Factors for Pulmonary Autograft Dilation After Ross Aortic Valve Replacement

Brown, J., Ruzmetov, M., Rodefeld, M., Mahomed, Y. & Turrentine, M., May 2007, In : Annals of Thoracic Surgery. 83, 5, p. 1781-1789 9 p.

Research output: Contribution to journalArticle

Autografts
Aortic Valve
Dilatation
Lung
Incidence
65 Citations (Scopus)

In the adult mesenchymal stem cell population, source gender is a biologically relevant aspect of protective power

Crisostomo, P. R., Markel, T. A., Wang, M., Lahm, T., Lillemoe, K. D. & Meldrum, D. R., Aug 2007, In : Surgery. 142, 2, p. 215-221 7 p.

Research output: Contribution to journalArticle

Adult Stem Cells
Mesenchymal Stromal Cells
Population
Intercellular Signaling Peptides and Proteins
Reperfusion
18 Citations (Scopus)

Iron chelation acutely stimulates fetal human intestinal cell production of IL-6 and VEGF while decreasing HGF: The roles of p38, ERK, and JNK MAPK signaling

Markel, T. A., Crisostomo, P. R., Wang, M., Herring, C. M., Lahm, T., Meldrum, K. K., Lillemoe, K. D., Rescorla, F. & Meldrum, D. R., Apr 2007, In : American Journal of Physiology - Gastrointestinal and Liver Physiology. 292, 4

Research output: Contribution to journalArticle

Vascular Endothelial Growth Factor A
Interleukin-6
Iron
Epithelial Cells
Deferoxamine
21 Citations (Scopus)

Mechanical cavopulmonary assist for the univentricular Fontan circulation using a novel folding propeller blood pump

Throckmorton, A. L., Ballman, K. K., Myers, C. D., Litwak, K. N., Frankel, S. H. & Rodefeld, M., Nov 2007, In : ASAIO Journal. 53, 6, p. 734-741 8 p.

Research output: Contribution to journalArticle

Propellers
Blood
Pumps
Hydraulics
Hydrodynamics

Mediastinal germ cell tumors.

Kesler, K. & Einhorn, L., May 2007, In : Annals of Thoracic Surgery. 83, 5, p. 1915 1 p.

Research output: Contribution to journalArticle

Mediastinal Neoplasms
Germ Cell and Embryonal Neoplasms
53 Citations (Scopus)

Mesenchymal Stem Cells Attenuate Hypoxic Pulmonary Vasoconstriction by a Paracrine Mechanism

Patel, K. M., Crisostomo, P., Lahm, T., Markel, T., Herring, C., Wang, M., Meldrum, K. K., Lillemoe, K. D. & Meldrum, D. R., Dec 2007, In : Journal of Surgical Research. 143, 2, p. 281-285 5 p.

Research output: Contribution to journalArticle

Vasoconstriction
Mesenchymal Stromal Cells
Lung
Pulmonary Artery
Conditioned Culture Medium
5 Citations (Scopus)

Off-Pump Aortic Valve Bypass Using a Valved Apical-Aortic Conduit

Brown, J. & Gammie, J. S., Jun 2007, In : Operative Techniques in Thoracic and Cardiovascular Surgery. 12, 2, p. 85-94 10 p.

Research output: Contribution to journalArticle

Aortic Valve
17 Citations (Scopus)

Postoperative Outpatient Chest Tube Management: Initial Experience With a New Portable System

Rieger, K., Wroblewski, H. A., Brooks, J. A., Hammoud, Z. T. & Kesler, K., Aug 2007, In : Annals of Thoracic Surgery. 84, 2, p. 630-632 3 p.

Research output: Contribution to journalArticle

Chest Tubes
Outpatients
Air
Drainage
Hospital Costs
5 Citations (Scopus)

Prospective evaluation of serum amiodarone concentrations when administered via a nasogastric tube into the stomach conduit after transthoracic esophagectomy

Tisdale, J. E., Wroblewski, H. A., Hammoud, Z. T., Rieger, K., Young, J. V., Wall, D. S. & Kesler, K., Oct 2007, In : Clinical Therapeutics. 29, 10, p. 2226-2234 9 p.

Research output: Contribution to journalArticle

Esophagectomy
Amiodarone
Stomach
Serum
Lung
60 Citations (Scopus)
Polytetrafluoroethylene
Lung
Reoperation
Pathologic Constriction
Pulmonary Atresia
10 Citations (Scopus)

Right ventricular TNF resistance during endotoxemia: The differential effects on ventricular function

Markel, T. A., Crisostomo, P. R., Wang, M., Herrmann, J. L., Abarbanell, A. M. & Meldrum, D. R., Nov 2007, In : American Journal of Physiology - Regulatory Integrative and Comparative Physiology. 293, 5

Research output: Contribution to journalArticle

Endotoxemia
Ventricular Function
Endotoxins
Heart Ventricles
Receptors, Tumor Necrosis Factor, Type II
4 Citations (Scopus)

Selective protein kinase C inhibition attenuates pulmonary artery cytokine expression without affecting hypoxic pulmonary vasoconstriction

Tsai, B. M., Patel, K., Wang, M., Morrell, E. D., Crisostomo, P. R. & Meldrum, D. R., Jan 2007, In : Shock. 27, 1, p. 36-39 4 p.

Research output: Contribution to journalArticle

Vasoconstriction
Protein Kinase C
Pulmonary Artery
Cytokines
Lung
9 Citations (Scopus)

Sex differences in endothelial STAT3 mediate sex differences in myocardial inflammation

Wang, M., Zhang, W., Crisostomo, P., Markel, T., Meldrum, K. K., Fu, X. Y. & Meldrum, D. R., Sep 2007, In : American Journal of Physiology - Endocrinology and Metabolism. 293, 3

Research output: Contribution to journalArticle

Endothelial cells
Sex Characteristics
Endothelial Cells
Inflammation
Chemical activation
76 Citations (Scopus)

STAT3 mediates bone marrow mesenchymal stem cell VEGF production

Wang, M., Zhang, W., Crisostomo, P., Markel, T., Meldrum, K. K., Fu, X. Y. & Meldrum, D. R., Jun 2007, In : Journal of Molecular and Cellular Cardiology. 42, 6, p. 1009-1015 7 p.

Research output: Contribution to journalArticle

Mesenchymal Stromal Cells
Vascular Endothelial Growth Factor A
Bone Marrow
p38 Mitogen-Activated Protein Kinases
Knockout Mice
53 Citations (Scopus)

Stem cell mechanisms and paracrine effects: Potential in cardiac surgery

Crisostomo, P. R., Wang, M., Markel, T. A., Lahm, T., Abarbanell, A. M., Herrmann, J. L. & Meldrum, D. R., Oct 2007, In : Shock. 28, 4, p. 375-383 9 p.

Research output: Contribution to journalArticle

Thoracic Surgery
Stem Cells
Heart Diseases
Cytoprotection
Cell- and Tissue-Based Therapy
23 Citations (Scopus)

Stem Cells Improve Right Ventricular Functional Recovery After Acute Pressure Overload and Ischemia Reperfusion Injury

Wairiuko, G. M., Crisostomo, P. R., Wang, M., Morrell, E. D., Meldrum, K. K., Lillemoe, K. D. & Meldrum, D. R., Aug 2007, In : Journal of Surgical Research. 141, 2, p. 241-246 6 p.

Research output: Contribution to journalArticle

Reperfusion Injury
Stem Cells
Ventricular Pressure
Pressure
Heart Ventricles
16 Citations (Scopus)

Surgical Results of Arterial Switch Operation for Taussig-Bing Anomaly: Is Position of the Great Arteries a Risk Factor?

Rodefeld, M., Ruzmetov, M., Vijay, P., Fiore, A. C., Turrentine, M. & Brown, J., Apr 2007, In : Annals of Thoracic Surgery. 83, 4, p. 1451-1457 7 p.

Research output: Contribution to journalArticle

Double Outlet Right Ventricle
Arteries
Thoracic Aorta
Reoperation
Ventricular Outflow Obstruction
42 Citations (Scopus)

The critical role of vascular endothelial growth factor in pulmonary vascular remodeling after lung injury

Lahm, T., Crisostomo, P. R., Markel, T. A., Wang, M., Lillemoe, K. D. & Meldrum, D. R., Jul 2007, In : Shock. 28, 1, p. 4-14 11 p.

Research output: Contribution to journalArticle

Lung Injury
Vascular Endothelial Growth Factor A
Lung
Endothelial Cells
Emphysema
18 Citations (Scopus)

The Effect of Chronic Exogenous Androgen on Myocardial Function Following Acute Ischemia-Reperfusion in Hosts with Different Baseline Levels of Sex Steroids

Nam, U. H., Wang, M., Crisostomo, P. R., Markel, T. A., Lahm, T., Meldrum, K. K., Lillemoe, K. D. & Meldrum, D. R., Sep 2007, In : Journal of Surgical Research. 142, 1, p. 113-118 6 p.

Research output: Contribution to journalArticle

Androgens
Reperfusion
Testosterone
Ischemia
Dihydrotestosterone
40 Citations (Scopus)

The struggle for iron: Gastrointestinal microbes modulate the host immune response during infection

Markel, T. A., Crisostomo, P. R., Wang, M., Herring, C. M., Meldrum, K. K., Lillemoe, K. D. & Meldrum, D. R., Feb 1 2007, In : Journal of Leukocyte Biology. 81, 2, p. 393-400 8 p.

Research output: Contribution to journalArticle

Iron
Infection
Macrophages
Immune Tolerance
Necrotizing Enterocolitis
118 Citations (Scopus)

Treatment of non-small cell lung cancer, stage IIIB: ACCP evidence-based clinical practice guidelines (2nd edition)

Jett, J. R., Schild, S. E., Keith, R. L. & Kesler, K., Sep 2007, In : Chest. 132, 3 SUPPL.

Research output: Contribution to journalArticle

Evidence-Based Practice
Chemoradiotherapy
Practice Guidelines
Non-Small Cell Lung Carcinoma
Radiotherapy
8 Citations (Scopus)

When Reconstruction Fails or is Not Feasible: Valve Replacement Options in the Pediatric Population

Husain, S. A. & Brown, J., 2007, In : Pediatric Cardiac Surgery Annual. 10, 1, p. 117-124 8 p.

Research output: Contribution to journalArticle

Pediatrics
Population
Anatomy
Pathology
Growth
2006
80 Citations (Scopus)

17-β-Estradiol decreases p38 MAPK-mediated myocardial inflammation and dysfunction following acute ischemia

Wang, M., Tsai, B. M., Reiger, K. M., Brown, J. & Meldrum, D. R., Feb 2006, In : Journal of Molecular and Cellular Cardiology. 40, 2, p. 205-212 8 p.

Research output: Contribution to journalArticle

p38 Mitogen-Activated Protein Kinases
Estradiol
Ischemia
Inflammation
Estrogens
3 Citations (Scopus)
Heart Murmurs
Choristoma
Heart Neoplasms
Myocarditis
Heart Ventricles
45 Citations (Scopus)

Aortic Valve Bypass for the High-Risk Patient With Aortic Stenosis

Gammie, J. S., Brown, J., Brown, J. M., Poston, R. S., Pierson, R. N., Odonkor, P. N., White, C. S., Gottdiener, J. S. & Griffith, B. P., May 2006, In : Annals of Thoracic Surgery. 81, 5, p. 1605-1610 6 p.

Research output: Contribution to journalArticle

Aortic Valve Stenosis
Aortic Valve
Cardiopulmonary Bypass
Thoracic Aorta
Transplants
74 Citations (Scopus)

A prospective analysis of the incidence and risk factors associated with junctional ectopic tachycardia following surgery for congenital heart disease

Batra, A. S., Chun, D. S., Johnson, T., Maldonado, E. M., Kashyap, B. A., Maiers, J., Lindblade, C. L., Rodefeld, M., Brown, J. & Hubbard, J. E., Feb 2006, In : Pediatric Cardiology. 27, 1, p. 51-55 5 p.

Research output: Contribution to journalArticle

Ectopic Junctional Tachycardia
Heart Diseases
Incidence
Bundle of His
Cardiopulmonary Bypass
60 Citations (Scopus)

Can pulmonary conduit dysfunction and failure be reduced in infants and children less than age 2 years at initial implantation?

Karamlou, T., Blackstone, E. H., Hawkins, J. A., Jacobs, M. L., Kanter, K. R., Brown, J., Mavroudis, C., Caldarone, C. A., Williams, W. G. & McCrindle, B. W., Oct 2006, In : Journal of Thoracic and Cardiovascular Surgery. 132, 4

Research output: Contribution to journalArticle

Lung
Allografts
Neck
Pulmonary Valve Insufficiency
Heterografts
51 Citations (Scopus)
Venae Cavae
Lung
Superior Vena Cava
Veins
Superior Vena Cava Syndrome
13 Citations (Scopus)
Aortic Valve Stenosis
Reoperation
Newborn Infant
Heart Ventricles
Endocardial Fibroelastosis
9 Citations (Scopus)

Disparate IL-1β and iNOS gene expression in the aorta and pulmonary artery after endotoxemia

Tsai, B. M., Wang, M., Pitcher, J. M., Kher, A. & Meldrum, D. R., Feb 2006, In : Surgical Infections. 7, 1, p. 21-27 7 p.

Research output: Contribution to journalArticle

Endotoxemia
Nitric Oxide Synthase Type II
Interleukin-1
Pulmonary Artery
Aorta
4 Citations (Scopus)

Does endogenous testosterone mediate the lower preconditioning threshold in males?

Nelson, N. T., Mahomed, A. J., Pitcher, J. M., Tsai, B. M., Wang, M., Mahomed, Y., Brown, J., Crisostomo, P. & Meldrum, D. R., Mar 2006, In : Journal of Surgical Research. 131, 1, p. 86-90 5 p.

Research output: Contribution to journalArticle

Testosterone
Wounds and Injuries
Intraperitoneal Injections
Salmonella typhimurium
Sprague Dawley Rats
14 Citations (Scopus)

Endogenous estrogen mediates a higher threshold for endotoxin-induced myocardial protection in females

Pitcher, J. M., Wang, M., Tsai, B. M., Kher, A., Nelson, N. T. & Meldrum, D. R., Jan 2006, In : American Journal of Physiology - Regulatory Integrative and Comparative Physiology. 290, 1

Research output: Contribution to journalArticle

Endotoxins
Estrogens
Proestrus
Wounds and Injuries
p38 Mitogen-Activated Protein Kinases
124 Citations (Scopus)

Estrogen receptor-α mediates acute myocardial protection in females

Wang, M., Crisostomo, P., Wairiuko, G. M. & Meldrum, D. R., Jun 2006, In : American Journal of Physiology - Heart and Circulatory Physiology. 290, 6

Research output: Contribution to journalArticle

Estrogen Receptors
Ischemia
Sex Characteristics
Reperfusion
Cytokines
32 Citations (Scopus)

Evolution of aortic valve replacement in children: A single center experience

Ruzmetov, M., Vijay, P., Rodefeld, M., Turrentine, M. & Brown, J., Nov 10 2006, In : International Journal of Cardiology. 113, 2, p. 194-200 7 p.

Research output: Contribution to journalArticle

Aortic Valve
Reoperation
Heterografts
Prostheses and Implants
Aortic Valve Stenosis
26 Citations (Scopus)

Fate of the autograft and homograft following ross aortic valve replacement: Reoperative frequency, outcome, and management

Brown, J., Ruzmetov, M., Fukui, T., Rodefeld, M., Mahomed, Y. & Turrentine, M., Mar 2006, In : Journal of Heart Valve Disease. 15, 2, p. 253-260 8 p.

Research output: Contribution to journalArticle

Autografts
Aortic Valve
Allografts
Lung
Pediatrics
121 Citations (Scopus)

High passage number of stem cells adversely affects stem cell activation and myocardial protection

Crisostomo, P. R., Wang, M., Wairiuko, G. M., Morrell, E. D., Terrell, A. M., Seshadri, P., Nam, U. H. & Meldrum, D. R., Dec 2006, In : Shock. 26, 6, p. 575-580 6 p.

Research output: Contribution to journalArticle

Mesenchymal Stromal Cells
Stem Cells
Ischemia
Vascular Endothelial Growth Factor A
Lipopolysaccharides
219 Citations (Scopus)
Hepatocyte Growth Factor
p38 Mitogen-Activated Protein Kinases
Insulin-Like Growth Factor I
Vascular Endothelial Growth Factor A
Adipose Tissue
70 Citations (Scopus)

JAK/STAT/SOCS signaling circuits and associated cytokine-mediated inflammation and hypertrophy in the heart

Terrell, A. M., Crisostomo, P. R., Wairiuko, G. M., Wang, M., Morrell, E. D. & Meldrum, D. R., Sep 2006, In : Shock. 26, 3, p. 226-234 9 p.

Research output: Contribution to journalArticle

Suppressor of Cytokine Signaling Proteins
Janus Kinases
Cardiomegaly
Transducers
Cytokines