Pediatric Hematology/Oncology

Publications

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Review article
2020

Biomarkers for Allogeneic HCT Outcomes

Adom, D., Rowan, C., Adeniyan, T., Yang, J. & Paczesny, S., Apr 21 2020, In : Frontiers in immunology. 11, 673.

Research output: Contribution to journalReview article

Open Access
1 Scopus citations

Post-haematopoietic cell transplantation outcomes: why ST2 became a ‘golden nugget’ biomarker

Paczesny, S., Jan 1 2020, (Accepted/In press) In : British journal of haematology.

Research output: Contribution to journalReview article

2019

Biomarkers for Early Complications After Hematopoietic Stem Cell Transplantation

Rowan, C. M. & Paczesny, S., Mar 2019, In : Clinics in Laboratory Medicine. 39, 1, p. 61-72 12 p.

Research output: Contribution to journalReview article

4 Scopus citations

Clinical Proteomics for Post-Hematopoeitic Stem Cell Transplantation Outcomes

Paczesny, S. & Metzger, J., Mar 2019, In : Proteomics - Clinical Applications. 13, 2, 1800145.

Research output: Contribution to journalReview article

3 Scopus citations
2018

Biomarkers for posttransplantation outcomes

Paczesny, S., May 17 2018, In : Blood. 131, 20, p. 2193-2204 12 p.

Research output: Contribution to journalReview article

20 Scopus citations

Fanconi anaemia and cancer: An intricate relationship

Nalepa, G. & Clapp, D. W., Mar 1 2018, In : Nature Reviews Cancer. 18, 3, p. 168-185 18 p.

Research output: Contribution to journalReview article

67 Scopus citations

Introduction to a review series on emerging immunotherapies for hematologic diseases

Paczesny, S., Pavletic, S. Z. & Bollard, C. M., Jun 14 2018, In : Blood. 131, 24, p. 2617-2620 4 p.

Research output: Contribution to journalReview article

2 Scopus citations

The search for drug-targetable diagnostic, prognostic and predictive biomarkers in chronic graft-versus-host disease

Ren, H. G., Adom, D. & Paczesny, S., May 4 2018, In : Expert Review of Clinical Immunology. 14, 5, p. 389-404 16 p.

Research output: Contribution to journalReview article

4 Scopus citations
2017

Immunotherapeutic concepts to target acute myeloid leukemia: Focusing on the role of monoclonal antibodies, hypomethylating agents and the leukemic microenvironment

Gbolahan, O. B., Zeidan, A. M., Stahl, M., Zaid, M. A., Farag, S., Paczesny, S. & Konig, H., Aug 2017, In : International journal of molecular sciences. 18, 8, 1660.

Research output: Contribution to journalReview article

15 Scopus citations

National Institutes of Health Hematopoietic Cell Transplantation Late Effects Initiative: The Immune Dysregulation and Pathobiology Working Group Report

Gea-Banacloche, J., Komanduri, K. V., Carpenter, P., Paczesny, S., Sarantopoulos, S., Young, J. A., El Kassar, N., Le, R. Q., Schultz, K. R., Griffith, L. M., Savani, B. N. & Wingard, J. R., Jun 2017, In : Biology of Blood and Marrow Transplantation. 23, 6, p. 870-881 12 p.

Research output: Contribution to journalReview article

14 Scopus citations

Sonidegib: Mechanism of action, pharmacology, and clinical utility for advanced basal cell carcinomas

Jain, S., Song, R. & Xie, J., Mar 16 2017, In : OncoTargets and Therapy. 10, p. 1645-1653 9 p.

Research output: Contribution to journalReview article

29 Scopus citations

The Biology of Chronic Graft-versus-Host Disease: A Task Force Report from the National Institutes of Health Consensus Development Project on Criteria for Clinical Trials in Chronic Graft-versus-Host Disease

Cooke, K. R., Luznik, L., Sarantopoulos, S., Hakim, F. T., Jagasia, M., Fowler, D. H., van den Brink, M. R. M., Hansen, J. A., Parkman, R., Miklos, D. B., Martin, P. J., Paczesny, S., Vogelsang, G., Pavletic, S., Ritz, J., Schultz, K. R. & Blazar, B. R., Feb 1 2017, In : Biology of Blood and Marrow Transplantation. 23, 2, p. 211-234 24 p.

Research output: Contribution to journalReview article

104 Scopus citations

The role of MDM2 in promoting genome stability versus instability

Reza Saadatzadeh, M., Elmi, A. N., Pandya, P. H., Bijangi-Vishehsaraei, K., Ding, J., Stamatkin, C. W., Cohen-Gadol, A. A. & Pollok, K. E., Oct 23 2017, In : International journal of molecular sciences. 18, 10, 2216.

Research output: Contribution to journalReview article

10 Scopus citations

The ST2/IL-33 axis in immune cells during inflammatory diseases

Griesenauer, B. & Paczesny, S., Apr 24 2017, In : Frontiers in immunology. 8, APR, 475.

Research output: Contribution to journalReview article

126 Scopus citations
2016

CXCL10: Most consistent cGVHD biomarker?

Paczesny, S. & Zaid, M. A., Jun 16 2016, In : Blood. 127, 24, p. 2950-2951 2 p.

Research output: Contribution to journalReview article

6 Scopus citations

Deciphering the role of hedgehog signaling in pancreatic cancer

Gu, D., Schlotman, K. E. & Xie, J., Jan 1 2016, In : Journal of Biomedical Research. 30, 5, p. 353-360 8 p.

Research output: Contribution to journalReview article

23 Scopus citations

Emerging non-canonical functions and regulation by p53: p53 and stemness

Olivos, D. J. & Mayo, L. D., Dec 2016, In : International journal of molecular sciences. 17, 12, 1982.

Research output: Contribution to journalReview article

21 Scopus citations

Emerging targets for glioblastoma stem cell therapy

Safa, A. R., Saadatzadeh, M. R., Cohen-Gadol, A. A., Pollok, K. E. & Bijangi-Vishehsaraei, K., 2016, In : Journal of Biomedical Research. 30, 1, p. 19-31 13 p.

Research output: Contribution to journalReview article

24 Scopus citations

STAT3 in the systemic inflammation of cancer cachexia

Zimmers, T. A., Fishel, M. L. & Bonetto, A., Jun 1 2016, In : Seminars in Cell and Developmental Biology. 54, p. 28-41 14 p.

Research output: Contribution to journalReview article

74 Scopus citations

The Impact of Genomic Profiling for Novel Cancer Therapy - Recent Progress in Non-Small Cell Lung Cancer

Xie, J. & Zhang, X., Jan 20 2016, In : Journal of Genetics and Genomics. 43, 1, p. 3-10 8 p.

Research output: Contribution to journalReview article

4 Scopus citations
2015

Glioblastoma stem cells (GSCs) epigenetic plasticity and interconversion between differentiated non-GSCs and GSCs

Safa, A. R., Saadatzadeh, M. R., Cohen-Gadol, A. A., Pollok, K. E. & Bijangi-Vishehsaraei, K., Jun 1 2015, In : Genes and Diseases. 2, 2, p. 152-163 12 p.

Research output: Contribution to journalReview article

80 Scopus citations

Identifying therapeutic targets in gastric cancer: The current status and future direction

Yu, B. & Xie, J., May 27 2015, In : Acta Biochimica et Biophysica Sinica. 48, 1, p. 90-96 7 p.

Research output: Contribution to journalReview article

15 Scopus citations

Non-canonical Hh signaling in cancer—Current understanding and future directions

Gu, D. & Xie, J., Aug 27 2015, In : Cancers. 7, 3, p. 1684-1698 15 p.

Research output: Contribution to journalReview article

32 Scopus citations

Promising molecular mechanisms responsible for gemcitabine resistance in cancer

Jia, Y. & Xie, J., Dec 1 2015, In : Genes and Diseases. 2, 4, p. 299-306 8 p.

Research output: Contribution to journalReview article

27 Scopus citations

The Hedgehog pathway: role in cell differentiation, polarity and proliferation

Jia, Y., Wang, Y. & Xie, J., Jan 1 2015, In : Archives of Toxicology. 89, 2, p. 179-191 13 p.

Research output: Contribution to journalReview article

38 Scopus citations

Various forms of tissue damage and danger signals following hematopoietic stem-cell transplantation

Ramadan, A. & Paczesny, S., Jan 1 2015, In : Frontiers in immunology. 6, JAN, 00014.

Research output: Contribution to journalReview article

26 Scopus citations
2014

Biomarkers for fatal immune response to stem cell treatment could reduce mortality

Paczesny, S., Jan 1 2014, In : Biomarkers in Medicine. 8, 1, p. 65-68 4 p.

Research output: Contribution to journalReview article

3 Scopus citations

Opportunities and challenges of proteomics in pediatric patients: Circulating biomarkers after hematopoietic stem cell transplantation as a successful example

Paczesny, S., Duncan, C., Jacobsohn, D., Krance, R., Leung, K., Carpenter, P., Bollard, C., Renbarger, J. & Cooke, K., Dec 1 2014, In : Proteomics - Clinical Applications. 8, 11-12, p. 837-850 14 p.

Research output: Contribution to journalReview article

3 Scopus citations

Targeting DNA repair pathways for cancer treatment: What's new?

Kelley, M. R., Logsdon, D. & Fishel, M. L., May 2014, In : Future Oncology. 10, 7, p. 1215-1237 23 p.

Research output: Contribution to journalReview article

91 Scopus citations
2013

Discovery and validation of graft-versus-host disease biomarkers

Paczesny, S., Jan 24 2013, In : Blood. 121, 4, p. 585-594 10 p.

Research output: Contribution to journalReview article

95 Scopus citations

Manufacturing and banking of mesenchymal stem cells

Thirumala, S., Goebel, W. S. & Woods, E. J., May 1 2013, In : Expert Opinion on Biological Therapy. 13, 5, p. 673-691 19 p.

Research output: Contribution to journalReview article

56 Scopus citations

Targeting hedgehog signaling in cancer: Research and clinical developments

Xie, J., Bartels, C. M., Barton, S. W. & Gu, D., Oct 25 2013, In : OncoTargets and Therapy. 6, p. 1425-1435 11 p.

Research output: Contribution to journalReview article

53 Scopus citations
2012
96 Scopus citations

Integration of DNA damage and repair with murine double-minute 2 (Mdm2) in Tumorigenesis

Lehman, J. A. & Mayo, L. D., Dec 2012, In : International journal of molecular sciences. 13, 12, p. 16373-16386 14 p.

Research output: Contribution to journalReview article

2 Scopus citations
24 Scopus citations

Squamous cell carcinomas of the head and neck in Fanconi anemia: Risk, prevention, therapy, and the need for guidelines

Scheckenbach, K., Wagenmann, M., Freund, M., Schipper, J. & Hanenberg, H., 2012, In : Klinische Padiatrie. 224, 3, p. 132-138 7 p.

Research output: Contribution to journalReview article

21 Scopus citations
2011

Clinical implications of hedgehog signaling pathway inhibitors

Liu, H., Gu, D. & Xie, J., 2011, In : Chinese Journal of Cancer. 30, 1, p. 13-26 14 p.

Research output: Contribution to journalReview article

Open Access
20 Scopus citations

Hedgehog signaling in skin cancers

Li, C., Chi, S. & Xie, J., Aug 2011, In : Cellular Signalling. 23, 8, p. 1235-1243 9 p.

Research output: Contribution to journalReview article

36 Scopus citations

Mutations of the SLX4 gene in Fanconi anemia

Kim, Y., Lach, F. P., Desetty, R., Hanenberg, H., Auerbach, A. D. & Smogorzewska, A., Feb 1 2011, In : Nature genetics. 43, 2, p. 142-146 5 p.

Research output: Contribution to journalReview article

238 Scopus citations

Targeting the anti-apoptotic protein c-FLIP for cancer therapy

Safa, A. R. & Pollok, K. E., Jun 1 2011, In : Cancers. 3, 2, p. 1639-1671 33 p.

Research output: Contribution to journalReview article

96 Scopus citations
2010

Activation of the hedgehog-signaling pathway in human cancer and the clinical implications

Yang, L., Xie, G., Fan, Q. & Xie, J., Jan 1 2010, In : Oncogene. 29, 4, p. 469-481 13 p.

Research output: Contribution to journalReview article

222 Scopus citations

Controlling the Mdm2-Mdmx-p53 circuit

Waning, D. L., Lehman, J. A., Batuello, C. N. & Mayo, L. D., 2010, In : Pharmaceuticals. 3, 5, p. 1576-1593 18 p.

Research output: Contribution to journalReview article

22 Scopus citations

Redox regulation of DNA repair: Implications for human health and cancer therapeutic development

Luo, M., He, H., Kelley, M. R. & Georgiadis, M. M., Jun 1 2010, In : Antioxidants and Redox Signaling. 12, 11, p. 1247-1269 23 p.

Research output: Contribution to journalReview article

84 Scopus citations

The centrosome and mitotic spindle apparatus in cancer and senescence

Schmidt, S., Essmann, F., Cirstea, I. C., Kuck, F., Thakur, H. C., Singh, M., Kletke, A., Jänicke, R. U., Wiek, C., Hanenberg, H., Ahmadian, M. R., Schulze-Osthoff, K., Nürnberg, B. & Piekorz, R. P., Nov 15 2010, In : Cell Cycle. 9, 22, p. 4469-4473 5 p.

Research output: Contribution to journalReview article

21 Scopus citations
2009

Acute graft-versus-host disease: New treatment strategies

Paczesny, S., Choi, S. W. & Ferrara, J. L. M., Nov 2009, In : Current opinion in hematology. 16, 6, p. 427-436 10 p.

Research output: Contribution to journalReview article

49 Scopus citations

Clinical grade adult stem cell banking

Thirumala, S., Goebel, W. S. & Woods, E. J., Oct 14 2009, In : Organogenesis. 5, 3, p. 143-154 12 p.

Research output: Contribution to journalReview article

74 Scopus citations

Going ape as an approach to cancer therapeutics

Bapat, A., Fishel, M. L. & Kelley, M. R., Mar 1 2009, In : Antioxidants and Redox Signaling. 11, 3, p. 651-667 17 p.

Research output: Contribution to journalReview article

78 Scopus citations

Mesenchymal stem cells for treatment and prevention of graft-versus-host disease after allogeneic hematopoietic cell transplantation

Toubai, T., Paczesny, S., Shono, Y., Tanaka, J., Lowler, K. P., Malter, C. T., Kasai, M. & Imamura, M., 2009, In : Current Stem Cell Research and Therapy. 4, 4, p. 252-259 8 p.

Research output: Contribution to journalReview article

43 Scopus citations
26 Scopus citations

The many functions of APE1/Ref-1: Not only a DNA repair enzyme

Tell, G., Quadrifoglio, F., Tiribelli, C. & Kelley, M. R., Mar 1 2009, In : Antioxidants and Redox Signaling. 11, 3, p. 601-619 19 p.

Research output: Contribution to journalReview article

309 Scopus citations