Transplant Surgery

Publications 2002 2019

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2019

Combination therapy for severe portopulmonary hypertension in a child allows for liver transplantation

Serrano, R. M., Subbarao, G., Mangus, R., Montgomery, G. & Johansen, M., Jan 1 2019, In : Pediatric Transplantation. e13461.

Research output: Contribution to journalArticle

Liver Transplantation
Hypertension
Pediatrics
Therapeutics
Lung

Comparison of methods of providing analgesia after pancreas transplant: IV opioid analgesia versus transversus abdominis plane block with liposomal bupivacaine or continuous catheter infusion

Yeap, Y. L., Fridell, J. A., Wu, D., Mangus, R., Kroepfl, E., Wolfe, J. & Powelson, J. A., Jan 1 2019, In : Clinical Transplantation. e13581.

Research output: Contribution to journalArticle

Abdominal Muscles
Bupivacaine
Analgesia
Opioid Analgesics
Pancreas

Expanding the Donor Pool With the Use of Extended Criteria Donation After Circulatory Death Livers

Mihaylov, P., Mangus, R., Ekser, B., Cabrales, A., Timsina, L., Fridell, J., Lacerda, M., Ghabril, M., Nephew, L., Chalasani, N. & Kubal, C. A., Jan 1 2019, In : Liver Transplantation.

Research output: Contribution to journalArticle

Liver Transplantation
Liver
Warm Ischemia
Research Ethics Committees
Age Factors

Metabolomic Characterization of Human Model of Liver Rejection Identifies Aberrancies Linked to Cyclooxygenase (COX) and Nitric Oxide Synthase (NOS)

Skill, N., Elliott, C. M., Ceballos, B., Saxena, R., Pepin, R., Bettcher, L., Ellensberg, M., Raftery, D., Maluccio, M., Ekser, B., Mangus, R. & Kubal, C. A., Jun 11 2019, In : Annals of transplantation. 24, p. 341-349 9 p.

Research output: Contribution to journalArticle

Metabolomics
Prostaglandin-Endoperoxide Synthases
Nitric Oxide Synthase
Liver
Biopsy
2 Citations (Scopus)

One-year Incidence of Infection in Pediatric Intestine Transplantation

Clouse, J. W., Kubal, C. A., Fridell, J. A. & Mangus, R., Mar 1 2019, In : The Pediatric infectious disease journal. 38, 3, p. 219-223 5 p.

Research output: Contribution to journalArticle

Intestines
Transplantation
Pediatrics
Transplants
Virus Diseases

Postoperative Atrial Fibrillation and Flutter in Liver Transplantation: An Important Predictor of Early and Late Morbidity and Mortality

Rachwan, R. J., Kutkut, I., Hathaway, T. J., Timsina, L. R., Kubal, C. A., Lacerda, M. A., Ghabril, M. S., Bourdillon, P. D. & Mangus, R. S., Jan 1 2019, (Accepted/In press) In : Liver Transplantation.

Research output: Contribution to journalArticle

Atrial Flutter
Liver Transplantation
Atrial Fibrillation
Morbidity
Mortality

Prognostic Impact of Peritransplant Serum Sodium Concentrations in Liver Transplantation

Mihaylov, P., Nagai, S., Ekser, B., Mangus, R., Fridell, J. & Kubal, C., Jul 16 2019, In : Annals of transplantation. 24, p. 418-425 8 p.

Research output: Contribution to journalArticle

Blood Transfusion
Liver Transplantation
Hyponatremia
Sodium
Serum
2018

Challenges with intestine and multivisceral re-transplantation: Importance of timing of re-transplantation and optimal immunosuppression

Kubal, C. A., Pennington, K., Fridell, J., Ekser, B., Muhaylov, P. & Mangus, R., Jan 1 2018, In : Annals of Transplantation. 23, p. 98-104 7 p.

Research output: Contribution to journalArticle

Immunosuppression
Intestines
Transplantation
Bone Marrow
Transplants
2 Citations (Scopus)

Class II Human Leukocyte Antigen Epitope Mismatch Predicts De Novo Donor-Specific Antibody Formation After Liver Transplantation

Kubal, C. A., Mangus, R., Ekser, B., Mihaylov, P., Ceballos, B., Higgins, N., Chalasani, N., Ghabril, M., Nephew, L. & Lobashevsky, A., Aug 1 2018, In : Liver Transplantation. 24, 8, p. 1101-1108 8 p.

Research output: Contribution to journalArticle

HLA-D Antigens
HLA Antigens
Liver Transplantation
Antibody Formation
Epitopes

Comparable outcomes in intestinal retransplantation: Single-center cohort study

Ekser, B., Kubal, C. A., Fridell, J. A. & Mangus, R., Jul 1 2018, In : Clinical Transplantation. 32, 7, e13290.

Research output: Contribution to journalArticle

Cohort Studies
Transplantation
Transplants
Graft Survival
Pancreatitis
3 Citations (Scopus)

Comparison of Histidine-Tryptophan-Ketoglutarate and University of Wisconsin preservation solutions in pediatric liver transplantation

Mangus, R., Schroering, J. R., Hathaway, T. J., Kubal, C. A. & Fridell, J. A., Jan 1 2018, In : Pediatric Transplantation. 22, 6, e13252.

Research output: Contribution to journalArticle

Histidine
Tryptophan
Liver Transplantation
Pediatrics
Transplants
1 Citation (Scopus)

Complications in pediatric intestine transplantation in the absence of peri-operative donor or recipient bowel decontamination

Clouse, J. W., Kubal, C. A., Fridell, J. A. & Mangus, R., Jan 1 2018, (Accepted/In press) In : Pediatric Transplantation.

Research output: Contribution to journalArticle

Decontamination
Intestines
Transplantation
Tissue Donors
Pediatrics

Computed Tomography Measures of Nutrition in Patients With End-Stage Liver Disease Provide a Novel Approach to Characterize Deficits

Bush, W. J., Davis, J. P., Maluccio, M., Kubal, C. A., Salisbury, J. B. & Mangus, R., Jan 1 2018, (Accepted/In press) In : Transplantation Proceedings.

Research output: Contribution to journalArticle

End Stage Liver Disease
Tomography
Intra-Abdominal Fat
Subcutaneous Fat
Sarcopenia

De Novo Head and Neck Cancer After Liver Transplant With Antibody-Based Immunosuppression Induction

Graham, R. C., Mella, J. S. & Mangus, R., Dec 1 2018, In : Transplantation Proceedings. 50, 10, p. 3661-3666 6 p.

Research output: Contribution to journalArticle

Liver Neoplasms
Head and Neck Neoplasms
Immunosuppression
Transplants
Antibodies
5 Citations (Scopus)

Excellent outcomes in combined liver-kidney transplantation: Impact of kidney donor profile index and delayed kidney transplantation

Ekser, B., Mangus, R., Kubal, C. A., Powelson, J. A., Fridell, J. A. & Goggins, W. C., Feb 1 2018, In : Liver Transplantation. 24, 2, p. 222-232 11 p.

Research output: Contribution to journalArticle

Liver Transplantation
Kidney Transplantation
Tissue Donors
Kidney
Survival

Impact of deceased donor cardiac arrest time on postpancreas transplant graft function and survival

Schroering, J. R., Mangus, R., Powelson, J. A. & Fridell, J. A., Sep 1 2018, In : Transplantation Direct. 4, 9, e381.

Research output: Contribution to journalArticle

Open Access
Graft Survival
Heart Arrest
Transplants
Lipase
Amylases
1 Citation (Scopus)

Impact of Volatile Anesthetic Agents on Early Clinical Outcomes in Liver Transplantation

Mangus, R., Kinsella, S. B., Farar, D. T., Fridell, J. A., Woolf, L. T. & Kubal, C. A., Jun 1 2018, In : Transplantation Proceedings. 50, 5, p. 1372-1377 6 p.

Research output: Contribution to journalArticle

Liver Transplantation
Anesthetics
Transplants
Reperfusion Injury
Alanine Transaminase

Multivisceral transplant is a viable treatment option for patients with non-resectable intra-abdominal fibromatosis

Chi, Z., Mangus, R., Kubal, C. A., Chen, S. & Lin, J., Jan 1 2018, (Accepted/In press) In : Clinical Transplantation.

Research output: Contribution to journalArticle

Abdominal Fibromatosis
Transplants
Adenomatous Polyposis Coli
Recurrence
Catenins

Pancreas transplantation using compatible but non-identical ABO blood group donors

Nagaraju, S., Mangus, R., Powelson, J. A. & Fridell, J. A., Jul 1 2018, In : Clinical Transplantation. 32, 7, e13284.

Research output: Contribution to journalArticle

Pancreas Transplantation
Blood Group Antigens
Blood Donors
Hemolysis
Pancreas

Post-intestine transplant graft-vs-host disease associated with inclusion of a liver graft and with a high mortality risk

Clouse, J. W., Kubal, C. A., Fridell, J. A., Pearsall, E. J. & Mangus, R., Jan 1 2018, (Accepted/In press) In : Clinical Transplantation. e13409.

Research output: Contribution to journalArticle

Graft vs Host Disease
Intestines
Transplants
Mortality
Liver
4 Citations (Scopus)

Posttransplant complications in adult recipients of intestine grafts without bowel decontamination

Clouse, J. W., Kubal, C. A., Fridell, J. A. & Mangus, R., May 1 2018, In : Journal of Surgical Research. 225, p. 125-130 6 p.

Research output: Contribution to journalArticle

Decontamination
Intestines
Transplants
Abdominal Abscess
Mycoses
1 Citation (Scopus)

Steroid-free three-drug maintenance regimen for pancreas transplant alone: Comparison of induction with rabbit antithymocyte globulin +/− rituximab

Fridell, J. A., Mangus, R., Chen, J. M., Taber, T., Cabrales, A. E., Sharfuddin, A., Yaqub, M. & Powelson, J. A., Dec 1 2018, In : American Journal of Transplantation. 18, 12, p. 3000-3006 7 p.

Research output: Contribution to journalArticle

Antilymphocyte Serum
Pancreas
Steroids
Maintenance
Rabbits
2017
11 Citations (Scopus)

A Novel Approach in Combined Liver and Kidney Transplantation with Long-term Outcomes

Ekser, B., Mangus, R., Fridell, W., Kubal, C. A., Nagai, S., Kinsella, S. B., Bayt, D. R., Bell, T. M., Powelson, J. A., Goggins, W. C. & Tector, A. J., May 1 2017, In : Annals of Surgery. 265, 5, p. 1000-1008 9 p.

Research output: Contribution to journalArticle

Liver Transplantation
Kidney Transplantation
Kidney
Delayed Graft Function
Transplants
1 Citation (Scopus)

Donation After Circulatory Arrest in Pancreas Transplantation: A Report of 10 Cases

Fridell, J. A., Mangus, R., Thomas, C. M., Kubal, C. A. & Powelson, J. A., Dec 1 2017, In : Transplantation Proceedings. 49, 10, p. 2310-2314 5 p.

Research output: Contribution to journalArticle

Pancreas Transplantation
Transplants
Pancreas
Tissue Donors
Graft Survival

Graft quality matters: Impact of KDPI and delayed kidney transplantation in combined liver-kidney transplantation

Ekser, B., Mangus, R., Kubal, C. A., Powelson, J. A., Fridell, J. A. & Goggins, W. C., 2017, (Accepted/In press) In : Clinical Transplantation.

Research output: Contribution to journalArticle

Liver Transplantation
Kidney Transplantation
Transplants
11 Citations (Scopus)

Severe Sarcopenia and Increased Fat Stores in Pediatric Patients With Liver, Kidney, or Intestine Failure

Mangus, R., Bush, W. J., Kubal, C. A. & Miller, C., Jun 9 2017, (Accepted/In press) In : Journal of Pediatric Gastroenterology and Nutrition.

Research output: Contribution to journalArticle

Sarcopenia
Intestines
Subcutaneous Fat
Fats
Pediatrics
2016
10 Citations (Scopus)

Cytomegalovirus Infection after Intestinal/Multivisceral Transplantation: A Single-Center Experience with 210 Cases

Nagai, S., Mangus, R., Anderson, E., Ekser, B., Kubal, C. A., Fridell, J. A. & Tector, A. J., Feb 1 2016, In : Transplantation. 100, 2, p. 451-460 10 p.

Research output: Contribution to journalArticle

Cytomegalovirus Infections
Transplantation
Cytomegalovirus
Immunoglobulins
Antilymphocyte Serum
9 Citations (Scopus)

Immunogenicity of renal microvascular endothelial cells from genetically modified pigs

Wang, Z. Y., Li, P., Butler, J. R., Blankenship, R. L., Downey, S. M., Montgomery, J. B., Nagai, S., Estrada, J. L., Tector, M. F. & Joseph Tector, A., 2016, In : Transplantation. 100, 3, p. 533-537 5 p.

Research output: Contribution to journalArticle

Swine
Endothelial Cells
Kidney
Antibodies
Immunoglobulin G
6 Citations (Scopus)

Intestinal Graft Failure: Should We Perform the Allograft Enterectomy Before or With Retransplantation?

Nagai, S., Mangus, R., Anderson, E., Ekser, B., Kubal, C. A., Fridell, J. A. & Tector, A. J., Feb 19 2016, (Accepted/In press) In : Transplantation.

Research output: Contribution to journalArticle

Allografts
Transplants
Transplantation
Enteritis
Graft Rejection
7 Citations (Scopus)

Modified glycan models of pig-to-human xenotransplantation do not enhance the human-anti-pig T cell response

Butler, J. R., Wang, Z. Y., Martens, G. R., Ladowski, J. M., Li, P., Tector, M. & Tector, A. J., Mar 1 2016, In : Transplant Immunology. 35, p. 47-51 5 p.

Research output: Contribution to journalArticle

Heterologous Transplantation
Polysaccharides
Swine
T-Lymphocytes
Clustered Regularly Interspaced Short Palindromic Repeats
5 Citations (Scopus)

New Hope for Liver Xenotransplantation

Tector, J., Mar 4 2016, (Accepted/In press) In : Annals of Surgery.

Research output: Contribution to journalArticle

Heterologous Transplantation
Liver
17 Citations (Scopus)

Optimization of Perioperative Conditions to Prevent Ischemic Cholangiopathy in Donation After Circulatory Death Donor Liver Transplantation

Kubal, C., Mangus, R., Fridell, J., Saxena, R., Rush, N., Wingler, M., Ekser, B. & Tector, J., Apr 29 2016, (Accepted/In press) In : Transplantation.

Research output: Contribution to journalArticle

Liver Transplantation
Tissue Donors
Cold Ischemia
Warm Ischemia
Tissue Plasminogen Activator
37 Citations (Scopus)
Portal Vein
Liver Transplantation
Thrombosis
Tissue and Organ Procurement
Graft Survival
1 Citation (Scopus)

Recurrence of Hyperoxaluria and Kidney Disease after Combined Intestine-Kidney Transplantation for Enteric Hyperoxaluria

Ekser, B., Mangus, R., Kubal, C. A., Fridell, J. A., Powelson, J. A., Nagaraju, S., Mihaylov, P., Phillips, C., Saxena, R. & Goggins, W. C., Jul 14 2016, (Accepted/In press) In : American Journal of Nephrology. p. 85-91 7 p.

Research output: Contribution to journalArticle

Hyperoxaluria
Kidney Diseases
Kidney Transplantation
Intestines
Oxalates
17 Citations (Scopus)

Silencing porcine CMAH and GGTA1 genes significantly reduces xenogeneic consumption of human platelets by porcine livers

Butler, J. R., Paris, L. L., Blankenship, R. L., Sidner, R. A., Martens, G. R., Ladowski, J. M., Li, P., Estrada, J. L., Tector, M. & Joseph Tector, A., 2016, In : Transplantation. 100, 3, p. 571-576 6 p.

Research output: Contribution to journalArticle

Swine
Blood Platelets
Liver
Genes
Heterologous Transplantation
23 Citations (Scopus)

Silencing porcine genes significantly reduces human-anti-pig cytotoxicity profiles: an alternative to direct complement regulation

Butler, J. R., Martens, G. R., Estrada, J. L., Reyes, L. M., Ladowski, J. M., Galli, C., Perota, A., Cunningham, C. M., Tector, M. & Joseph Tector, A., Apr 21 2016, (Accepted/In press) In : Transgenic Research. p. 1-9 9 p.

Research output: Contribution to journalArticle

Gene Silencing
cytotoxicity
complement
Swine
swine
9 Citations (Scopus)

Silencing the porcine iGb3s gene does not affect Galα3Gal levels or measures of anticipated pig-to-human and pig-to-primate acute rejection

Butler, J. R., Skill, N., Priestman, D. L., Platt, F. M., Li, P., Estrada, J. L., Martens, G. R., Ladowski, J. M., Tector, M. & Tector, A. J., Mar 1 2016, In : Xenotransplantation. 23, 2, p. 106-116 11 p.

Research output: Contribution to journalArticle

Glycosyltransferases
Primates
Swine
Genes
Glycosphingolipids

Spontaneous bacterial peritonitis

Ekser, B. & Mangus, R., 2016, (Accepted/In press) In : The Lancet.

Research output: Contribution to journalArticle

Tissue Adhesions
End Stage Liver Disease
Chronic Hepatitis C
Peritonitis
Bacterial Infections
2 Citations (Scopus)

The fate of human platelets exposed to porcine renal endothelium: a single-pass model of platelet uptake in domestic and genetically modified porcine organs

Butler, J. R., Martens, G. R., Li, P., Wang, Z. Y., Estrada, J. L., Ladowski, J. M., Tector, M. & Tector, A. J., Feb 1 2016, In : Journal of Surgical Research. 200, 2, p. 698-706 9 p.

Research output: Contribution to journalArticle

Endothelium
Swine
Blood Platelets
Kidney
Heterologous Transplantation
2015
16 Citations (Scopus)

A brief history of clinical xenotransplantation

Cooper, D. K. C., Ekser, B. & Tector, A. J., Nov 1 2015, In : International Journal of Surgery. 23, p. 205-210 6 p.

Research output: Contribution to journalArticle

Heterologous Transplantation
Pan troglodytes
Transplants
Testis
Swine
4 Citations (Scopus)

Alcohol abuse in deceased liver donors: Impact on post-transplant outcomes

Mangus, R., Kubal, C. A., Fridell, J. A., Pena, J. M., Frost, E. M. & Joseph Tector, A., Jan 1 2015, In : Liver International. 35, 1, p. 171-175 5 p.

Research output: Contribution to journalArticle

Alcoholism
Tissue Donors
Transplants
Liver
Graft Survival
11 Citations (Scopus)

Allograft Pancreatectomy: Indications and Outcomes

Nagai, S., Powelson, J. A., Taber, T., Goble, M. L., Mangus, R. & Fridell, J. A., Sep 1 2015, In : American Journal of Transplantation. 15, 9, p. 2456-2464 9 p.

Research output: Contribution to journalArticle

Pancreatectomy
Allografts
Transplants
Pancreas
False Aneurysm
12 Citations (Scopus)

Current status of pig liver xenotransplantation

Ekser, B., Markmann, J. F. & Tector, A. J., Nov 1 2015, In : International Journal of Surgery. 23, p. 240-246 7 p.

Research output: Contribution to journalArticle

Heterologous Transplantation
Swine
Liver
Gene Deletion
Graft Survival
67 Citations (Scopus)

Efficient generation of genetically distinct pigs in a single pregnancy using multiplexed single-guide RNA and carbohydrate selection

Li, P., Estrada, J. L., Burlak, C., Montgomery, J., Butler, J. R., Santos, R. M., Wang, Z. Y., Paris, L. L., Blankenship, R. L., Downey, S. M., Tector, M. & Tector, A. J., Jan 1 2015, In : Xenotransplantation. 22, 1, p. 20-31 12 p.

Research output: Contribution to journalArticle

Guide RNA
Swine
Carbohydrates
Pregnancy
CRISPR-Cas Systems
9 Citations (Scopus)

Elevated alanine aminotransferase (ALT) in the deceased donor: Impact on early post-transplant liver allograft function

Mangus, R., Fridell, J. A., Kubal, C. A., Davis, J. P. & Joseph Tector, A., Feb 1 2015, In : Liver International. 35, 2, p. 524-531 8 p.

Research output: Contribution to journalArticle

Alanine Transaminase
Allografts
Tissue Donors
Graft Survival
Transplants
92 Citations (Scopus)

Evaluation of human and non-human primate antibody binding to pig cells lacking GGTA1/CMAH/β4GalNT2 genes

Estrada, J. L., Martens, G., Li, P., Adams, A., Newell, K. A., Ford, M. L., Butler, J. R., Sidner, R., Tector, M. & Tector, J., May 1 2015, In : Xenotransplantation. 22, 3, p. 194-202 9 p.

Research output: Contribution to journalArticle

Primates
Swine
Heterophile Antigens
Antibodies
Genes
13 Citations (Scopus)

Expression of NeuGc on Pig Corneas and Its Potential Significance in Pig Corneal Xenotransplantation

Lee, W., Miyagawa, Y., Long, C., Ekser, B., Walters, E., Ramsoondar, J., Ayares, D., Tector, A. J., Cooper, D. K. C. & Hara, H., Nov 12 2015, In : Cornea. 35, 1, p. 105-113 9 p.

Research output: Contribution to journalArticle

Heterologous Transplantation
Cornea
Swine
Galactose
Endothelial Cells
28 Citations (Scopus)

Immunobiological barriers to xenotransplantation

Cooper, D. K. C., Ekser, B. & Tector, A. J., Nov 1 2015, In : International Journal of Surgery. 23, p. 211-216 6 p.

Research output: Contribution to journalArticle

Heterologous Transplantation
Swine
Galactose
Primates
Immunosuppressive Agents

Impact of duration of diabetes on outcome following pancreas transplantation

Ekser, B., Mangus, R., Powelson, J. A., Goble, M. L., Mujtaba, M. A., Taber, T. & Fridell, J. A., Jun 1 2015, In : International Journal of Surgery. 18, p. 21-27 7 p.

Research output: Contribution to journalArticle

Pancreas Transplantation
Pancreas
Kidney Transplantation
Transplants
Allografts
13 Citations (Scopus)

Intestine and Multivisceral Transplantation: Current Status and Future Directions

Kubal, C. A., Mangus, R. & Tector, A. J., 2015, In : Current Gastroenterology Reports. 17, 1

Research output: Contribution to journalArticle

Intestines
Parenteral Nutrition
Transplantation
Lipids
Liver Diseases