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2019

Methionine Adenosyltransferase α1 Is Targeted to the Mitochondrial Matrix and Interacts with Cytochrome P450 2E1 to Lower Its Expression

Murray, B., Peng, H., Barbier-Torres, L., Robinson, A. E., Li, T. W. H., Fan, W., Tomasi, M. L., Gottlieb, R. A., Van Eyk, J., Lu, Z., Martínez-Chantar, M. L., Liangpunsakul, S., Skill, N. J., Mato, J. M. & Lu, S. C., Dec 1 2019, In : Hepatology. 70, 6, p. 2018-2034 17 p.

Research output: Contribution to journalArticle

1 Scopus citations

Microbiome predictors of dysbiosis and vre decolonization in patients with recurrent c. Difficile infections in a multi-center retrospective study

Santiago, M., Eysenbach, L., Allegretti, J., Aroniadis, O., Brandt, L. J., Fischer, M., Grinspan, A., Kelly, C., Morrow, C., Rodriguez, M., Osman, M., Kassam, Z., Smith, M. B. & Timberlake, S., Jan 1 2019, In : AIMS Microbiology. 5, 1, p. 1-18 18 p.

Research output: Contribution to journalArticle

Open Access

MicroRNA 362-3p Reduces hERG-related Current and Inhibits Breast Cancer Cells Proliferation

Assiri, A. A., Mourad, N., Shao, M., Kiel, P., Liu, W., Skaar, T. C. & Overholser, B. R., Nov 1 2019, In : Cancer genomics & proteomics. 16, 6, p. 433-442 10 p.

Research output: Contribution to journalArticle

Open Access

MicroRNA410 Inhibits Pulmonary Vascular Remodeling via Regulation of Nicotinamide Phosphoribosyltransferase

Gao, H., Chen, J., Chen, T., Wang, Y., Song, Y., Dong, Y., Zhao, S. & Machado, R. F., Dec 1 2019, In : Scientific reports. 9, 1, 9949.

Research output: Contribution to journalArticle

Open Access

Microsatellite Instability May Predict Response to Sipuleucel-T in Patients With Prostate Cancer

Zhang, K. J., Schneider, B. & Albany, C., Jan 1 2019, In : Clinical Genitourinary Cancer.

Research output: Contribution to journalArticle

MIND food and speed of processing training in older adults with low education, the MINDSpeed Alzheimer's disease prevention pilot trial

Clark, D. O., Xu, H., Moser, L., Adeoye, P., Lin, A. W., Tangney, C. C., Risacher, S. L., Saykin, A. J., Considine, R. V. & Unverzagt, F. W., Sep 2019, In : Contemporary Clinical Trials. 84, 105814.

Research output: Contribution to journalArticle

Mission reconnect: Protocol for a mobile and web-based self-directed complementary and integrative health program for veterans and their partners

Haun, J. N., Ballistrea, L. M., Melillo, C., Standifer, M., Kip, K., Paykel, J., Murphy, J. L., Fletcher, C. E., Mitchinson, A., Kozak, L., Taylor, S. L., Glynn, S. M. & Bair, M., May 2019, In : Journal of medical Internet research. 21, 5, e13666.

Research output: Contribution to journalArticle

Open Access

Model-guided antipsychotic dose reduction in schizophrenia: A pilot, single-blind randomized controlled trial

Ozawa, C., Bies, R. R., Pillai, N., Suzuki, T., Mimura, M. & Uchida, H., Jul 1 2019, In : Journal of Clinical Psychopharmacology. 39, 4, p. 329-335 7 p.

Research output: Contribution to journalArticle

1 Scopus citations

Modulation of the Tryptophan Hydroxylase 1/Monoamine Oxidase-A/5-Hydroxytryptamine/5-Hydroxytryptamine Receptor 2A/2B/2C Axis Regulates Biliary Proliferation and Liver Fibrosis During Cholestasis

Kyritsi, K., Chen, L., O'Brien, A., Francis, H., Hein, T. W., Venter, J., Wu, N., Ceci, L., Zhou, T., Zawieja, D., Gashev, A. A., Meng, F., Invernizzi, P., Fabris, L., Wu, C., Skill, N. J., Saxena, R., Liangpunsakul, S., Alpini, G. & Glaser, S. S., Jan 1 2019, (Accepted/In press) In : Hepatology.

Research output: Contribution to journalArticle

3 Scopus citations

Multiobjective Calibration of Disease Simulation Models Using Gaussian Processes

Sai, A., Vivas-Valencia, C., Imperiale, T. & Kong, N., Jan 1 2019, (Accepted/In press) In : Medical Decision Making.

Research output: Contribution to journalArticle

Multi-site investigation of strategies for the clinical implementation of CYP2D6 genotyping to guide drug prescribing

on behalf of the IGNITE Network, Oct 1 2019, In : Genetics in Medicine. 21, 10, p. 2255-2263 9 p.

Research output: Contribution to journalArticle

11 Scopus citations

Mutant p53 drives clonal hematopoiesis through modulating epigenetic pathway

Chen, S., Wang, Q., Yu, H., Capitano, M. L., Vemula, S., Nabinger, S. C., Gao, R., Yao, C., Kobayashi, M., Geng, Z., Fahey, A., Henley, D., Liu, S. Z., Barajas, S., Cai, W., Wolf, E. R., Ramdas, B., Cai, Z., Gao, H., Luo, N. & 12 others, Sun, Y., Wong, T. N., Link, D. C., Liu, Y., Boswell, H. S., Mayo, L. D., Huang, G., Kapur, R., Yoder, M. C., Broxmeyer, H. E., Gao, Z. & Liu, Y., Dec 1 2019, In : Nature communications. 10, 1, 5649.

Research output: Contribution to journalArticle

Open Access

Narrow-Band Imaging for Detection of Neoplasia at Colonoscopy: A Meta-analysis of Data From Individual Patients in Randomized Controlled Trials

Atkinson, N. S. S., Ket, S., Bassett, P., Aponte, D., De Aguiar, S., Gupta, N., Horimatsu, T., Ikematsu, H., Inoue, T., Kaltenbach, T., Leung, W. K., Matsuda, T., Paggi, S., Radaelli, F., Rastogi, A., Rex, D. K., Sabbagh, L. C., Saito, Y., Sano, Y., Saracco, G. M. & 6 others, Saunders, B. P., Senore, C., Soetikno, R., Vemulapalli, K. C., Jairath, V. & East, J. E., Aug 2019, In : Gastroenterology. 157, 2, p. 462-471 10 p.

Research output: Contribution to journalArticle

10 Scopus citations

Neck circumference and cardiovascular outcomes: Insights from the Jackson Heart Study

Pumill, C. A., Bush, C. G., Greiner, M. A., Hall, M. E., Dunlay, S. M., Correa, A., Curtis, L. H., Suzuki, T., Hardy, C., Blackshear, C. T., O'Brien, E. C. & Mentz, R. J., Jun 2019, In : American Heart Journal. 212, p. 72-79 8 p.

Research output: Contribution to journalArticle

New and Recurrent Colorectal Cancers After Resection: a Systematic Review and Meta-analysis of Endoscopic Surveillance Studies

Fuccio, L., Rex, D., Ponchon, T., Frazzoni, L., Dinis-Ribeiro, M., Bhandari, P., Dekker, E., Pellisè, M., Correale, L., van Hooft, J., Jover, R., Libanio, D., Radaelli, F., Alfieri, S., Bazzoli, F., Senore, C., Regula, J., Seufferlein, T., Rösch, T., Sharma, P. & 2 others, Repici, A. & Hassan, C., Apr 2019, In : Gastroenterology. 156, 5, p. 1309-1323.e3

Research output: Contribution to journalArticle

4 Scopus citations

Niraparib monotherapy for late-line treatment of ovarian cancer (QUADRA): a multicentre, open-label, single-arm, phase 2 trial

Moore, K. N., Secord, A. A., Geller, M. A., Miller, D. S., Cloven, N., Fleming, G. F., Wahner Hendrickson, A. E., Azodi, M., DiSilvestro, P., Oza, A. M., Cristea, M., Berek, J. S., Chan, J. K., Rimel, B. J., Matei, D. E., Li, Y., Sun, K., Luptakova, K., Matulonis, U. A. & Monk, B. J., May 2019, In : The lancet oncology. 20, 5, p. 636-648 13 p.

Research output: Contribution to journalArticle

14 Scopus citations

Non-traditional biomarkers and incident diabetes in the Diabetes Prevention Program: comparative effects of lifestyle and metformin interventions

Diabetes Prevention Program Research Group, Jan 1 2019, In : Diabetologia. 62, 1, p. 58-69 12 p.

Research output: Contribution to journalArticle

5 Scopus citations

Novel early life risk factors for adult pulmonary hypertension

Goss, K. N., Austin, E. D., Battiola, T. J., Tepper, R. S. & Lahm, T., Apr 1 2019, In : Pulmonary Circulation. 9, 2

Research output: Contribution to journalArticle

Open Access

Novel HLA class I alleles outside the extended DR3 haplotype are protective against autoimmune hepatitis

Lammert, C., McKinnon, E. J., Chalasani, N. & Phillips, E. J., Jun 1 2019, In : Clinical and translational gastroenterology. 10, 6, e-00032.

Research output: Contribution to journalArticle

Open Access

Obesity and insulin sensitivity effects on cardiovascular risk factors: Comparisons of obese dysglycemic youth and adults

The RISE Consortium, Nov 1 2019, In : Pediatric Diabetes. 20, 7, p. 849-860 12 p.

Research output: Contribution to journalArticle

Obeticholic acid for the treatment of non-alcoholic steatohepatitis: interim analysis from a multicentre, randomised, placebo-controlled phase 3 trial

REGENERATE Study Investigators, Dec 14 2019, In : The Lancet. 394, 10215, p. 2184-2196 13 p.

Research output: Contribution to journalArticle

8 Scopus citations

Older Age and Disease Duration Are Highly Associated with Hepatocellular Carcinoma in Patients with Autoimmune Hepatitis

Dakhoul, L., Jones, K. R., Gawrieh, S., Ghabril, M., McShane, C., Vuppalanchi, R., Vilar-Gomez, E., Nephew, L., Chalasani, N. & Lammert, C., Jan 1 2019, (Accepted/In press) In : Digestive Diseases and Sciences.

Research output: Contribution to journalArticle

1 Scopus citations

Oncologic Outcomes Following Surgical Management of Clinical Stage II Sex Cord Stromal Tumors

Calaway, A. C., Tachibana, I., Masterson, T. A., Foster, R. S., Einhorn, L. H. & Cary, C., May 2019, In : Urology. 127, p. 74-79 6 p.

Research output: Contribution to journalArticle

Ophthalmology in Critical Care

Parekh, P. H., Boente, C. S., Boente, R. D., Meeker, J. W. & Carlos, W., Aug 1 2019, In : Annals of the American Thoracic Society. 16, 8, p. 957-966 10 p.

Research output: Contribution to journalArticle

Opportunities to implement a sustainable genomic medicine program: lessons learned from the IGNITE Network

Levy, K. D., Blake, K., Fletcher-Hoppe, C., Franciosi, J., Goto, D., Hicks, J. K., Holmes, A. M., Kanuri, S. H., Madden, E. B., Musty, M. D., Orlando, L., Pratt, V. M., Ramos, M., Wu, R. & Ginsburg, G. S., Mar 1 2019, In : Genetics in Medicine. 21, 3, p. 743-747 5 p.

Research output: Contribution to journalArticle

2 Scopus citations

Outcomes of an RCT of videoconference vs. in-person or in-clinic nutrition and exercise in midlife adults with obesity

Clark, D. O., Keith, N., Weiner, M. & Xu, H., Apr 2019, In : Obesity Science and Practice. 5, 2, p. 111-119 9 p.

Research output: Contribution to journalArticle

Open Access

Overall survival of patients with recurrent pancreatic cancer treated with systemic therapy: A retrospective study

Gbolahan, O. B., Tong, Y., Sehdev, A., O'neil, B. & Shahda, S., May 17 2019, In : BMC Cancer. 19, 1, 468.

Research output: Contribution to journalArticle

Open Access
3 Scopus citations

Oxidative Stress in Response to Saturated Fat Ingestion Is Linked to Insulin Resistance and Hyperandrogenism in Polycystic Ovary Syndrome

González, F., Considine, R. V., Abdelhadi, O. A. & Acton, A. J., Nov 1 2019, In : The Journal of clinical endocrinology and metabolism. 104, 11, p. 5360-5371 12 p.

Research output: Contribution to journalArticle

1 Scopus citations

Oxidized Derivatives of Linoleic Acid in Pediatric Metabolic Syndrome: Is Their Pathogenic Role Modulated by the Genetic Background and the Gut Microbiota?

Tricò, D., Di Sessa, A., Caprio, S., Chalasani, N., Liu, W., Liang, T., Graf, J., Herzog, R. I., Johnson, C. D., Umano, G. R., Feldstein, A. E. & Santoro, N., Jan 10 2019, In : Antioxidants and Redox Signaling. 30, 2, p. 241-250 10 p.

Research output: Contribution to journalArticle

5 Scopus citations

Pain coping skills training for patients who catastrophize about pain prior to knee arthroplasty: A multisite randomized clinical trial

Riddle, D. L., Keefe, F. J., Ang, D. C., Slover, J., Jensen, M. P., Bair, M. J., Kroenke, K., Perera, R. A., Reed, S. D., McKee, D. & Dumenci, L., Feb 6 2019, In : Journal of Bone and Joint Surgery - American Volume. 101, 3, p. 218-227 10 p.

Research output: Contribution to journalArticle

9 Scopus citations

Parathyroid suppression therapy normalizes chronic kidney disease-induced elevations in cortical bone vascular perfusion: a pilot study

Aref, M. W., Swallow, E. A., Metzger, C. E., Chen, N., Moe, S. M. & Allen, M. R., Aug 1 2019, In : Osteoporosis International. 30, 8, p. 1693-1698 6 p.

Research output: Contribution to journalArticle

1 Scopus citations

Parental perspectives on decision-making about hypospadias surgery

Chan, K. H., Panoch, J., Carroll, A., Wiehe, S., Downs, S., Cain, M. P. & Frankel, R., Oct 2019, In : Journal of Pediatric Urology. 15, 5, p. 449.e1-449.e8

Research output: Contribution to journalArticle

2 Scopus citations

Patient and provider characteristics associated with communication about opioids: An observational study

Shields, C. G., Fuzzell, L. N., Christ, S. L. & Matthias, M. S., May 2019, In : Patient Education and Counseling. 102, 5, p. 888-894 7 p.

Research output: Contribution to journalArticle

1 Scopus citations

Patient-derived organoids as a potential model to predict response to PD-1/PD-L1 checkpoint inhibitors

Scognamiglio, G., De Chiara, A., Parafioriti, A., Armiraglio, E., Fazioli, F., Gallo, M., Aversa, L., Camerlingo, R., Cacciatore, F., Colella, G., Pili, R. & de Nigris, F., Jan 1 2019, (Accepted/In press) In : British Journal of Cancer.

Research output: Contribution to journalArticle

Open Access

Patiromer versus placebo to enable spironolactone use in patients with resistant hypertension and chronic kidney disease (AMBER): a phase 2, randomised, double-blind, placebo-controlled trial

Agarwal, R., Rossignol, P., Romero, A., Garza, D., Mayo, M. R., Warren, S., Ma, J., White, W. B. & Williams, B., Oct 26 2019, In : The Lancet. 394, 10208, p. 1540-1550 11 p.

Research output: Contribution to journalArticle

6 Scopus citations

PDK4 augments ER–mitochondria contact to dampen skeletal muscle insulin signaling during obesity

Thoudam, T., Ha, C. M., Leem, J., Chanda, D., Park, J. S., Kim, H. J., Jeon, J. H., Choi, Y. K., Liangpunsakul, S., Huh, Y. H., Kwon, T. H., Park, K. G., Harris, R. A., Park, K. S., Rhee, H. W. & Lee, I. K., Mar 1 2019, In : Diabetes. 68, 3, p. 571-586 16 p.

Research output: Contribution to journalArticle

6 Scopus citations

Peak post-transplant lung function in bilateral lung transplant recipients using a prediction model based on donor and recipient demographic characteristics

Azar, M., Krishnan, S., Stump, T. E., Gutteridge, D., Roe, D. W. & Hage, C., Aug 1 2019, In : Respiratory Medicine. 155, p. 29-35 7 p.

Research output: Contribution to journalArticle

1 Scopus citations

Pembrolizumab alone or in combination with chemotherapy as first-line therapy for patients with advanced gastric or gastroesophageal junction adenocarcinoma: results from the phase II nonrandomized KEYNOTE-059 study

Bang, Y. J., Kang, Y. K., Catenacci, D. V., Muro, K., Fuchs, C. S., Geva, R., Hara, H., Golan, T., Garrido, M., Jalal, S. I., Borg, C., Doi, T., Yoon, H. H., Savage, M. J., Wang, J., Dalal, R. P., Shah, S., Wainberg, Z. A. & Chung, H. C., Jan 1 2019, In : Gastric Cancer.

Research output: Contribution to journalArticle

Open Access
9 Scopus citations

Pembrolizumab in combination with ipilimumab as second-line or later therapy for advanced non–small-cell lung cancer: KEYNOTE-021 cohorts D and H

Gubens, M. A., Sequist, L. V., Stevenson, J. P., Powell, S. F., Villaruz, L. C., Gadgeel, S. M., Langer, C. J., Patnaik, A., Borghaei, H., Jalal, S., Fiore, J., Saraf, S., Raftopoulos, H. & Gandhi, L., Apr 1 2019, In : Lung Cancer. 130, p. 59-66 8 p.

Research output: Contribution to journalArticle

5 Scopus citations

Pembrolizumab in patients with programmed death ligand 1–positive advanced ovarian cancer: Analysis of KEYNOTE-028

Varga, A., Piha-Paul, S., Ott, P. A., Mehnert, J. M., Berton-Rigaud, D., Morosky, A., Yang, P., Ruman, J. & Matei, D., Feb 2019, In : Gynecologic oncology. 152, 2, p. 243-250 8 p.

Research output: Contribution to journalArticle

16 Scopus citations

Percutaneous Gastrostomy in Necrotizing Pancreatitis: Friend or Foe?

Roch, A. M., Carr, R. A., Watkins, J. L., Lehman, G., House, M. G., Nakeeb, A., Schmidt, C. M., Ceppa, E. P. & Zyromski, N. J., Jan 1 2019, (Accepted/In press) In : Journal of Gastrointestinal Surgery.

Research output: Contribution to journalArticle

Perioperative Risk Factors for Postoperative Delirium in Patients Undergoing Esophagectomy

Fuchita, M., Khan, S. H., Perkins, A. J., Gao, S., Wang, S., Kesler, K. & Khan, B., Jan 1 2019, In : Annals of Thoracic Surgery.

Research output: Contribution to journalArticle

3 Scopus citations

Personalized Decision Making in Early Stage Breast Cancer: Applying Clinical Prediction Models for Anthracycline Cardiotoxicity and Breast Cancer Mortality Demonstrates Substantial Heterogeneity of Benefit-Harm Trade-off

Upshaw, J. N., Ruthazer, R., Miller, K. D., Parsons, S. K., Erban, J. K., O'Neill, A. M., Demissei, B., Sledge, G., Wagner, L., Ky, B. & Kent, D. M., Aug 2019, In : Clinical breast cancer. 19, 4, p. 259-267.e1

Research output: Contribution to journalArticle

1 Scopus citations

Pharmacist-driven multidisciplinary pretreatment workup process for hepatitis C care: A novel model for same-day pretreatment workup

Houck, K. K., Ifeachor, A. P., Fleming, B. S., Andres, A. M., O'Donovan, K. N., Johnson, A. J. & Liangpunsakul, S., Jan 1 2019, In : Journal of the American Pharmacists Association.

Research output: Contribution to journalArticle

Open Access
4 Scopus citations

Pharmacokinetics and pharmacodynamics of ropinirole in patients with prolactinomas

Liu, S., Hu, C., Peters, J., Tsang, A., Cremers, S., Bies, R. & Page-Wilson, G., Feb 2019, In : British Journal of Clinical Pharmacology. 85, 2, p. 366-376 11 p.

Research output: Contribution to journalArticle

Pharmacological, mechanistic, and pharmacokinetic assessment of novel_ melatonin-tamoxifen drug conjugates as breast cancer drugs

Hasan, M., Marzouk, M. A., Adhikari, S., Wright, T. D., Miller, B. P., Matossian, M. D., Elliott, S., Wright, M., Alzoubi, M., Collins-Burow, B. M., Burow, M. E., Holzgrabe, U., Zlotos, D. P., Stratford, R. E. & Witt-Enderby, P. A., Jan 1 2019, In : Molecular pharmacology. 96, 2, p. 272-296 25 p.

Research output: Contribution to journalArticle

2 Scopus citations

Pharmacological Management of Delirium in the Intensive Care Unit: A Randomized Pragmatic Clinical Trial

Khan, B. A., Perkins, A. J., Campbell, N. L., Gao, S., Farber, M. O., Wang, S., Khan, S. H., Zarzaur, B. L. & Boustani, M. A., May 2019, In : Journal of the American Geriatrics Society. 67, 5, p. 1057-1065 9 p.

Research output: Contribution to journalArticle

4 Scopus citations

Phase 1 study of EUS-guided photodynamic therapy for locally advanced pancreatic cancer

DeWitt, J. M., Sandrasegaran, K., O'Neil, B., House, M. G., Zyromski, N. J., Sehdev, A., Perkins, S. M., Flynn, J., McCranor, L. & Shahda, S., Feb 2019, In : Gastrointestinal endoscopy. 89, 2, p. 390-398 9 p.

Research output: Contribution to journalArticle

5 Scopus citations

Phase II trial of single agent amrubicin in patients with previously treated advanced thymic malignancies

Hellyer, J. A., Gubens, M. A., Cunanan, K. M., Padda, S. K., Burns, M., Spittler, A. J., Riess, J. W., San Pedro-Salcedo, M., Ramchandran, K. J., Neal, J. W., Wakelee, H. A. & Loehrer, P. J., Nov 2019, In : Lung Cancer. 137, p. 71-75 5 p.

Research output: Contribution to journalArticle