Pediatric Infectious Disease

Publications 1991 2019

2017
10 Citations (Scopus)

Plasmodium falciparum EPCR-binding PfEMP1 expression increases with malaria disease severity and is elevated in retinopathy negative cerebral malaria

Shabani, E., Hanisch, B., Opoka, R. O., Lavstsen, T. & John, C., Oct 13 2017, In : BMC Medicine. 15, 1, 183.

Research output: Contribution to journalArticle

Cerebral Malaria
Plasmodium falciparum
Protein C
Malaria
Plasmodium falciparum erythrocyte membrane protein 1
1 Citation (Scopus)

Sero-catalytic and Antibody Acquisition Models to Estimate Differing Malaria Transmission Intensities in Western Kenya

Weber, G. E., White, M. T., Babakhanyan, A., Sumba, P. O., Vulule, J., Ely, D., John, C., Angov, E., Lanar, D., Dutta, S., Narum, D. L., Horii, T., Cowman, A., Beeson, J., Smith, J., Kazura, J. W. & Dent, A. E., Dec 1 2017, In : Scientific Reports. 7, 1, 16821.

Research output: Contribution to journalArticle

Catalytic Antibodies
Kenya
Malaria
Antibodies
Antigens
6 Citations (Scopus)

Supporting global health at the pediatric department level: Why and how

Pitt, M. B., Moore, M. A., John, C., Batra, M., Butteris, S. M., Airewele, G. E., Suchdev, P. S. & Steinhoff, M. C., Jun 1 2017, In : Pediatrics. 139, 6, e20163939.

Research output: Contribution to journalArticle

Pediatrics
Global Health

The Benjamin H. Kean travel fellowship in tropical medicine: Assessment of impact at 15 years

Carman, A. S. & John, C., 2017, In : American Journal of Tropical Medicine and Hygiene. 97, 3, p. 958-963 6 p.

Research output: Contribution to journalArticle

Tropical Medicine
Foster Home Care
Professional Practice
Manuscripts
Postal Service
2018
4 Citations (Scopus)

Admission EEG findings in diverse paediatric cerebral malaria populations predict outcomes

Postels, D. G., Wu, X., Li, C., Kaplan, P. W., Seydel, K. B., Taylor, T. E., Kousa, Y. A., Idro, R., Opoka, R., John, C. & Birbeck, G. L., May 22 2018, In : Malaria Journal. 17, 1, 208.

Research output: Contribution to journalArticle

Cerebral Malaria
Electroencephalography
Pediatrics
Uganda
Population
3 Citations (Scopus)

Chitinase-3-like 1 is a biomarker of acute kidney injury and mortality in paediatric severe malaria NCT01255215 NCT

Conroy, A. L., Hawkes, M. T., Elphinstone, R., Opoka, R. O., Namasopo, S., Miller, C., John, C. & Kain, K. C., Feb 15 2018, In : Malaria Journal. 17, 1, 82.

Research output: Contribution to journalArticle

Chitinases
Acute Kidney Injury
Malaria
Biomarkers
Pediatrics
4 Citations (Scopus)

High rate of inappropriate blood transfusions in the management of children with severe anemia in Ugandan hospitals

Opoka, R. O., Ssemata, A. S., Oyang, W., Nambuya, H., John, C., Tumwine, J. K. & Karamagi, C., Jul 18 2018, In : BMC Health Services Research. 18, 1, 566.

Research output: Contribution to journalArticle

Blood Transfusion
Anemia
Hemoglobins
Inpatients
Uganda
5 Citations (Scopus)

Inhaled nitric oxide and cognition in pediatric severe malaria: A randomized double-blind placebo controlled trial

Bangirana, P., Conroy, A. L., Opoka, R. O., Hawkes, M. T., Hermann, L., Miller, C., Namasopo, S., Liles, W. C., John, C. & Kain, K. C., Jan 1 2018, In : PLoS One. 13, 1, e0191550.

Research output: Contribution to journalArticle

Pediatrics
cognition
malaria
Cognition
Malaria
3 Citations (Scopus)

Lack of mortality in 22 children with sickle cell anemia and severe malarial anemia

Opoka, R. O., Bangirana, P., Idro, R., Shabani, E., Namazzi, R. & John, C., Jan 1 2018, In : Pediatric Blood and Cancer. 65, 1, e26745.

Research output: Contribution to journalArticle

Sickle Cell Anemia
Sickle Hemoglobin
Anemia
Child Mortality
Malaria

Malaria

Bhumbra, S. S. & John, C., Jan 1 2018, The 5-Minute Pediatric Consult, 8th Edition. Wolters Kluwer Health, p. 568-569 2 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

Malaria
8 Citations (Scopus)

Sharing antimicrobial reports for pediatric stewardship (SHARPS): A quality improvement collaborative

SHARPS Collaborative, Jan 1 2018, In : Journal of the Pediatric Infectious Diseases Society. 7, 2, p. 124-128 5 p.

Research output: Contribution to journalArticle

Quality Improvement
Pediatrics
Benchmarking
Learning
Hospitalized Child
1 Citation (Scopus)

Single low-dose primaquine for blocking transmission of Plasmodium falciparum malaria - a proposed model-derived age-based regimen for sub-Saharan Africa

Taylor, W. R., Naw, H. K., Maitland, K., Williams, T. N., Kapulu, M., D'Alessandro, U., Berkley, J. A., Bejon, P., Okebe, J., Achan, J., Amambua, A. N., Affara, M., Nwakanma, D., van Geertruyden, J. P., Mavoko, M., Lutumba, P., Matangila, J., Brasseur, P., Piola, P., Randremanana, R. & 24 others, Lasry, E., Fanello, C., Onyamboko, M., Schramm, B., Yah, Z., Jones, J., Fairhurst, R. M., Diakite, M., Malenga, G., Molyneux, M., Rwagacondo, C., Obonyo, C., Gadisa, E., Aseffa, A., Loolpapit, M., Henry, M. C., Dorsey, G., John, C., Sirima, S. B., Barnes, K. I., Kremsner, P., Day, N. P., White, N. J. & Mukaka, M., Jan 18 2018, In : BMC Medicine. 16, 1, 11.

Research output: Contribution to journalArticle

Primaquine
Falciparum Malaria
Africa South of the Sahara
Anemia
Glucosephosphate Dehydrogenase Deficiency
2 Citations (Scopus)

Travelers' diarrhea in children: A blind spot in the expert panel guidelines on prevention and treatment

on behalf of the Pediatric Interest Group, International Society of Travel Medicine, Feb 1 2018, In : Journal of Travel Medicine. 25, 1, tax075.

Research output: Contribution to journalLetter

Optic Disk
Diarrhea
Guidelines
Therapeutics
2019
2 Citations (Scopus)

Acute kidney injury is associated with impaired cognition and chronic kidney disease in a prospective cohort of children with severe malaria

Conroy, A. L., Opoka, R. O., Bangirana, P., Idro, R., Ssenkusu, J. M., Datta, D., Hodges, J. S., Morgan, C. & John, C., May 21 2019, In : BMC medicine. 17, 1, 1 p.

Research output: Contribution to journalArticle

Open Access
Chronic Renal Insufficiency
Acute Kidney Injury
Cognition
Malaria
Odds Ratio
1 Citation (Scopus)

Adherence to clinical guidelines is associated with reduced inpatient mortality among children with severe anemia in Ugandan hospitals

Opoka, R. O., Ssemata, A. S., Oyang, W., Nambuya, H., John, C., Karamagi, C. & Tumwine, J. K., Jan 1 2019, In : PLoS One. 14, 1, e0210982.

Research output: Contribution to journalArticle

Child Mortality
anemia
Anemia
Inpatients
Guidelines
1 Citation (Scopus)

Autoantibody levels are associated with acute kidney injury, anemia and post-discharge morbidity and mortality in Ugandan children with severe malaria

Rivera-Correa, J., Conroy, A. L., Opoka, R. O., Batte, A., Namazzi, R., Ouma, B., Bangirana, P., Idro, R., Schwaderer, A. L., John, C. C. & Rodriguez, A., Dec 1 2019, In : Scientific reports. 9, 1, 14940.

Research output: Contribution to journalArticle

Open Access
Phosphatidylserines
Acute Kidney Injury
Autoantibodies
Malaria
Anemia

Blood use in sub-Saharan Africa: a systematic review of current data

Dhabangi, A., Dzik, W. H., Idro, R., John, C., Butler, E. K., Spijker, R. & van Hensbroek, M. B., Jan 1 2019, In : Transfusion.

Research output: Contribution to journalReview article

Africa South of the Sahara

Caregivers and community perceptions of blood transfusion for children with severe anaemia in Uganda

Dhabangi, A., Idro, R., John, C., Dzik, W. H., Opoka, R., Siu, G. E., Ayebare, F. & van Hensbroek, M. B., Feb 1 2019, In : Transfusion Medicine. 29, 1, p. 61-67 7 p.

Research output: Contribution to journalArticle

Uganda
Blood Transfusion
Caregivers
Anemia
HIV
1 Citation (Scopus)

Case Report: Birth Outcome and Neurodevelopment in Placental Malaria Discordant Twins

Conroy, A. L., Bangirana, P., Muhindo, M. K., Kakuru, A., Jagannathan, P., Opoka, R. O., Liechty, E. A., Nakalembe, M., Kamya, M. R., Dorsey, G. & John, C., Mar 1 2019, In : The American journal of tropical medicine and hygiene. 100, 3, p. 552-555 4 p.

Research output: Contribution to journalArticle

Malaria
Parturition
Pregnancy
Placenta
Language

Community perceptions of paediatric severe anaemia in Uganda

Dhabangi, A., Idro, R., John, C., Dzik, W. H., Siu, G. E., Opoka, R. O., Ayebare, F. & Van Hensbroek, M. B., Jan 1 2019, In : PLoS One. 14, 1, e0209476.

Research output: Contribution to journalArticle

Pediatrics
Uganda
anemia
Anemia
splenomegaly

Comparison of non-magnetic and magnetic beads multiplex assay for assessment of Plasmodium falciparum antibodies

Ondigo, B. N., Park, G. S., Ayieko, C., Nyangahu, D. D., Wasswa, R. & John, C., Jan 1 2019, In : PeerJ. 2019, 1, e6120.

Research output: Contribution to journalArticle

Plasmodium falciparum
Assays
Antigens
antibodies
Antibodies

HIV infection drives IgM and IgG3 subclass bias in Plasmodium falciparum-specific and total immunoglobulin concentration in Western Kenya

Odhiambo, E. O., Datta, D., Guyah, B., Ayodo, G., Ondigo, B. N., Abong'O, B. O., John, C. & Frosch, A. E. P., Aug 30 2019, In : Malaria Journal. 18, 1, 297.

Research output: Contribution to journalArticle

Open Access
Kenya
Plasmodium falciparum
HIV Infections
Immunoglobulin M
Immunoglobulins
3 Citations (Scopus)
Open Access
Microbiology
Malaria
Health
Mortality
6 Citations (Scopus)

Whole-Blood Transcriptional Signatures Composed of Erythropoietic and NRF2-Regulated Genes Differ Between Cerebral Malaria and Severe Malarial Anemia

Nallandhighal, S., Park, G. S., Ho, Y. Y., Opoka, R. O., John, C. & Tran, T., Jan 1 2019, In : The Journal of infectious diseases. 219, 1, p. 154-164 11 p.

Research output: Contribution to journalArticle

Cerebral Malaria
Anemia
Genes
Reticulocytes
Malaria

Zinc for infection prevention in sickle cell anemia (zips): Study protocol for a randomized placebo-controlled trial in ugandan children with sickle cell anemia

Datta, D., Namazzi, R., Conroy, A. L., Cusick, S. E., Hume, H. A., Tagoola, A., Ware, R. E., Opoka, R. O. & John, C., Jul 26 2019, In : Trials. 20, 1, 460.

Research output: Contribution to journalArticle

Open Access
Sickle Cell Anemia
Zinc
Randomized Controlled Trials
Placebos
Infection