Pediatric Infectious Disease

Publications

Article

Autoantibody levels are associated with acute kidney injury, anemia and post-discharge morbidity and mortality in Ugandan children with severe malaria

Rivera-Correa, J., Conroy, A. L., Opoka, R. O., Batte, A., Namazzi, R., Ouma, B., Bangirana, P., Idro, R., Schwaderer, A. L., John, C. C. & Rodriguez, A., Dec 1 2019, In : Scientific reports. 9, 1, 14940.

Research output: Contribution to journalArticle

Open Access
1 Scopus citations

Blackwater Fever in Ugandan Children With Severe Anemia is Associated With Poor Postdischarge Outcomes: A Prospective Cohort Study

Opoka, R. O., Waiswa, A., Harriet, N., John, C. C., Tumwine, J. K. & Karamagi, C., May 23 2020, In : Clinical infectious diseases : an official publication of the Infectious Diseases Society of America. 70, 11, p. 2247-2254 8 p.

Research output: Contribution to journalArticle

Open Access
1 Scopus citations

Caregivers and community perceptions of blood transfusion for children with severe anaemia in Uganda

Dhabangi, A., Idro, R., John, C. C., Dzik, W. H., Opoka, R., Siu, G. E., Ayebare, F. & van Hensbroek, M. B., Feb 1 2019, In : Transfusion Medicine. 29, 1, p. 61-67 7 p.

Research output: Contribution to journalArticle

Case report: Birth outcome and neurodevelopment in placental malaria discordant twins

Conroy, A. L., Bangirana, P., Muhindo, M. K., Kakuru, A., Jagannathan, P., Opoka, R. O., Liechty, E. A., Nakalembe, M., Kamya, M. R., Dorsey, G. & John, C. C., Jan 1 2019, In : American Journal of Tropical Medicine and Hygiene. 100, 3, p. 552-555 4 p.

Research output: Contribution to journalArticle

1 Scopus citations
6 Scopus citations

Cerebral malaria is associated with long-term mental health disorders: A cross sectional survey of a long-term cohort

Idro, R., Kakooza-Mwesige, A., Asea, B., Ssebyala, K., Bangirana, P., Opoka, R. O., Lubowa, S. K., Semrud-Clikeman, M., John, C. C. & Nalugya, J., Mar 31 2016, In : Malaria Journal. 15, 1, 184.

Research output: Contribution to journalArticle

25 Scopus citations

Cerebrospinal fluid cytokine levels and cognitive impairment in cerebral malaria

John, C. C., Panoskaltsis-Mortari, A., Opoka, R. O., Park, G. S., Orchard, P. J., Jurek, A. M., Idro, R., Byarugaba, J. & Boivin, M. J., Feb 2008, In : American Journal of Tropical Medicine and Hygiene. 78, 2, p. 198-205 8 p.

Research output: Contribution to journalArticle

Open Access
103 Scopus citations

Cerebrospinal fluid kynurenine and kynurenic acid concentrations are associated with coma duration and long-term neurocognitive impairment in Ugandan children with cerebral malaria

Holmberg, D., Franzén-Röhl, E., Idro, R., Opoka, R. O., Bangirana, P., Sellgren, C. M., Wickström, R., Färnert, A., Schwieler, L., Engberg, G. & John, C. C., Jul 28 2017, In : Malaria Journal. 16, 1, 303.

Research output: Contribution to journalArticle

10 Scopus citations

Changes in B Cell Populations and Merozoite Surface Protein-1-Specific Memory B Cell Responses after Prolonged Absence of Detectable P. falciparum Infection

Ayieko, C., Maue, A. C., Jura, W. G. Z. O., Noland, G. S., Ayodo, G., Rochford, R. & John, C. C., Jun 27 2013, In : PloS one. 8, 6, e67230.

Research output: Contribution to journalArticle

22 Scopus citations

Chitinase-3-like 1 is a biomarker of acute kidney injury and mortality in paediatric severe malaria NCT01255215 NCT

Conroy, A. L., Hawkes, M. T., Elphinstone, R., Opoka, R. O., Namasopo, S., Miller, C., John, C. C. & Kain, K. C., Feb 15 2018, In : Malaria Journal. 17, 1, 82.

Research output: Contribution to journalArticle

4 Scopus citations

Clinical comparison of retinopathy-positive and retinopathy-negative cerebral Malaria

Villaverde, C., Namazzi, R., Shabani, E., Opoka, R. O. & John, C., 2017, In : American Journal of Tropical Medicine and Hygiene. 96, 5, p. 1176-1184 9 p.

Research output: Contribution to journalArticle

12 Scopus citations

Community perceptions of paediatric severe anaemia in Uganda

Dhabangi, A., Idro, R., John, C., Dzik, W. H., Siu, G. E., Opoka, R. O., Ayebare, F. & Van Hensbroek, M. B., Jan 1 2019, In : PLoS One. 14, 1, e0209476.

Research output: Contribution to journalArticle

Comparison of non-magnetic and magnetic beads multiplex assay for assessment of Plasmodium falciparum antibodies

Ondigo, B. N., Park, G. S., Ayieko, C., Nyangahu, D. D., Wasswa, R. & John, C. C., Jan 1 2019, In : PeerJ. 2019, 1, e6120.

Research output: Contribution to journalArticle

Comparison of Risk of Recrudescent Fever in Children With Kawasaki Disease Treated With Intravenous Immunoglobulin and Low-Dose vs High-Dose Aspirin

Platt, B., Belarski, E., Manaloor, J., Ofner, S., Carroll, A. E., John, C. C. & Wood, J. B., Jan 3 2020, In : JAMA Network Open. 3, 1, p. e1918565

Research output: Contribution to journalArticle

Open Access

Concomitant fundoplication with gastrostomy: A two-state comparison showing continued use of reflux medications

Fox, D., Campagna, E. J., Finnell, S. M. E., Partrick, D. A. & Kempe, A., Jan 1 2016, In : Journal of pediatric gastroenterology and nutrition. 63, 6, p. e163-e168

Research output: Contribution to journalArticle

Conversion of a single-facility pediatric antimicrobial stewardship program to multi-facility application with computerized provider order entry and clinical decision support

Webber, E. C., Warhurst, H. M., Smith, S. S., Cox, E. G., Crumby, A. S. & Nichols, K. R., Dec 1 2013, In : Applied Clinical Informatics. 4, 4, p. 556-568 13 p.

Research output: Contribution to journalArticle

6 Scopus citations
2 Scopus citations

Decrease in numbers of naive and resting B cells in HIV-infected Kenyan Adults leads to a proportional increase in total and plasmodium falciparum-specific atypical memory B cells

Frosch, A. E., Odumade, O. A., Taylor, J. J., Ireland, K., Ayodo, G., Ondigo, B., Narum, D. L., Vulule, J. & John, C. C., Jun 15 2017, In : Journal of Immunology. 198, 12, p. 4629-4638 10 p.

Research output: Contribution to journalArticle

7 Scopus citations

Delayed iron does not alter cognition or behavior among children with severe malaria and iron deficiency

Ssemata, A. S., Hickson, M., Ssenkusu, J. M., Cusick, S. E., Nakasujja, N., Opoka, R. O., Kroupina, M., Georgieff, M. K., Bangirana, P. & John, C. C., Jan 1 2020, (Accepted/In press) In : Pediatric Research.

Research output: Contribution to journalArticle

Delaying Iron therapy until 28 days after antimalarial treatment is associated with greater Iron incorporation and equivalent hematologic recovery after 56 days in children: A randomized controlled trial

Cusick, S. E., Opoka, R. O., Abrams, S. A., John, C. C., Georgieff, M. K. & Mupere, E., Jan 1 2016, In : Journal of Nutrition. 146, 9, p. 1769-1774 6 p.

Research output: Contribution to journalArticle

10 Scopus citations

Delaying the start of iron until 28 days after antimalarial treatment is associated with lower incidence of subsequent illness in children with malaria and iron deficiency

Jaramillo, E. G., Mupere, E., Opoka, R. O., Hodges, J. S., Lund, T. C., Georgieff, M. K., John, C. & Cusick, S. E., Aug 1 2017, In : PLoS One. 12, 8, e0183977.

Research output: Contribution to journalArticle

2 Scopus citations
9 Scopus citations

Differing causes of lactic acidosis and deep breathing in cerebral malaria and severe malarial anemia may explain differences in acidosis-related mortality

Brand, N. R., Opoka, R. O., Hamre, K. E. S. & John, C., Sep 1 2016, In : PLoS One. 11, 9, e0163728.

Research output: Contribution to journalArticle

6 Scopus citations

Effect of transmission intensity on hotspots and micro-epidemiology of malaria in sub-Saharan Africa

on behalf of The Hotspot Group Authors, Jun 30 2017, In : BMC medicine. 15, 1, 121.

Research output: Contribution to journalArticle

12 Scopus citations

Efficacy of limited cefuroxime prophylaxis in pediatric patients after cardiovascular surgery

Knoderer, C. A., Cox, E. G., Berg, M. D., Webster, A. H. & Turrentine, M. W., May 15 2011, In : American Journal of Health-System Pharmacy. 68, 10, p. 909-914 6 p.

Research output: Contribution to journalArticle

6 Scopus citations

Elevated Cerebrospinal Fluid Tau Protein Concentrations on Admission Are Associated with Long-term Neurologic and Cognitive Impairment in Ugandan Children with Cerebral Malaria

Datta, D., Conroy, A. L., Castelluccio, P. F., Ssenkusu, J. M., Park, G. S., Opoka, R. O., Bangirana, P., Idro, R., Saykin, A. J. & John, C. C., Mar 3 2020, In : Clinical Infectious Diseases. 70, 6, p. 1161-1168 8 p.

Research output: Contribution to journalArticle

Elevated cerebrospinal fluid tumour necrosis factor is associated with acute and long-term neurocognitive impairment in cerebral malaria

Shabani, E., Ouma, B. J., Idro, R., Bangirana, P., Opoka, R. O., Park, G. S., Conroy, A. L. & John, C. C., Jul 2017, In : Parasite Immunology. 39, 7, e12438.

Research output: Contribution to journalArticle

12 Scopus citations

Escherichia coli bacteremia, epididymo-orchitis, and scrotal abscess in a neonate

Stark, J. E., Bellman, L. A., Kamel, S. H., Whittam, B. M., Christenson, J. C. & Webber, E. C., Jan 1 2012, In : Journal of the Pediatric Infectious Diseases Society. 1, 4, p. 340-342 3 p., pis057.

Research output: Contribution to journalArticle

1 Scopus citations

Esophageal diverticulum: A complication of histoplasmosis in children

Steiner, S. J., Cox, E. G., Gupta, S. K., Kleiman, M. B. & Fitzgerald, J. F., Mar 2005, In : Journal of Pediatrics. 146, 3, p. 426-428 3 p.

Research output: Contribution to journalArticle

7 Scopus citations

Exploring experimental cerebral malaria pathogenesis through the characterisation of host-derived plasma microparticle protein content

Tiberti, N., Latham, S. L., Bush, S., Cohen, A., Opoka, R. O., John, C. C., Juillard, A., Grau, G. E. & Combes, V., Dec 5 2016, In : Scientific reports. 6, 37871.

Research output: Contribution to journalArticle

14 Scopus citations

Fluorosis because of prolonged voriconazole therapy in a teenager with acute myelogenous leukemia

Skiles, J. L., Imel, E. A., Christenson, J. C., Bell, J. E. & Hulbert, M. L., Nov 10 2011, In : Journal of Clinical Oncology. 29, 32, p. e779-e782

Research output: Contribution to journalArticle

22 Scopus citations

Hepatitis A, B, and C

Christenson, J. & Manaloor, J. J., Oct 1 2016, In : Pediatrics in Review. 37, 10, p. 426-438 13 p.

Research output: Contribution to journalArticle

High rate of inappropriate blood transfusions in the management of children with severe anemia in Ugandan hospitals

Opoka, R. O., Ssemata, A. S., Oyang, W., Nambuya, H., John, C. C., Tumwine, J. K. & Karamagi, C., Jul 18 2018, In : BMC Health Services Research. 18, 1, 566.

Research output: Contribution to journalArticle

4 Scopus citations

HIV infection drives IgM and IgG3 subclass bias in Plasmodium falciparum-specific and total immunoglobulin concentration in Western Kenya

Odhiambo, E. O., Datta, D., Guyah, B., Ayodo, G., Ondigo, B. N., Abong'O, B. O., John, C. C. & Frosch, A. E. P., Aug 30 2019, In : Malaria Journal. 18, 1, 297.

Research output: Contribution to journalArticle

Open Access

Host biomarkers are associated with response to therapy and long-term mortality in pediatric severe malaria

Conroy, A. L., Hawkes, M., McDonald, C. R., Kim, H., Higgins, S. J., Barker, K. R., Namasopo, S., Opoka, R. O., John, C., Liles, W. C. & Kain, K. C., 2016, In : Open Forum Infectious Diseases. 3, 3, ofw134.

Research output: Contribution to journalArticle

9 Scopus citations

Ileocecal histoplasmosis simulating crohn disease in a patient with hyperimmunoglobulin e syndrome

Steiner, S. J., Kleiman, M. B., Corkins, M. R., Christenson, J. C. & Wheat, L. J., Aug 2009, In : Pediatric Infectious Disease Journal. 28, 8, p. 744-746 3 p.

Research output: Contribution to journalArticle

20 Scopus citations

Impact of a national guideline on antibiotic selection for hospitalized pneumonia

Pediatric Research in Inpatient Settings Network, Apr 2017, In : Pediatrics. 139, 4, e20163231.

Research output: Contribution to journalArticle

7 Scopus citations

Implementing Extended-Infusion Cefepime as Standard of Care in a Children’s Hospital: A Prospective Descriptive Study

Nichols, K. R., Karmire, L. C., Cox, E. G., Kays, M. B. & Knoderer, C. A., Apr 16 2015, In : Annals of Pharmacotherapy. 49, 4, p. 419-426 8 p.

Research output: Contribution to journalArticle

5 Scopus citations

Increased length of stay and costs associated with weekend admissions for failure to thrive

Thompson, R. T., Bennett, W. E., Finnell, S. M. E., Downs, S. M. & Carroll, A. E., Mar 2013, In : Pediatrics. 131, 3, p. e805-e810

Research output: Contribution to journalArticle

12 Scopus citations

Influenza and parainfluenza viral infections in children

Fox, T. G. & Christenson, J. C., Jun 1 2014, In : Pediatrics in Review. 35, 6, p. 217-228 12 p.

Research output: Contribution to journalArticle

6 Scopus citations

Inhaled nitric oxide and cognition in pediatric severe malaria: A randomized double-blind placebo controlled trial

Bangirana, P., Conroy, A. L., Opoka, R. O., Hawkes, M. T., Hermann, L., Miller, C., Namasopo, S., Liles, W. C., John, C. C. & Kain, K. C., Jan 2018, In : PloS one. 13, 1, e0191550.

Research output: Contribution to journalArticle

6 Scopus citations

Inhaled nitric oxide as adjunctive therapy for severe malaria: a randomized controlled trial

Hawkes, M. T., Conroy, A. L., Opoka, R. O., Hermann, L., Thorpe, K. E., McDonald, C., Kim, H., Higgins, S., Namasopo, S., John, C., Miller, C., Liles, W. C. & Kain, K. C., Oct 29 2015, In : Malaria Journal. 14, 1, 946.

Research output: Contribution to journalArticle

32 Scopus citations

Interferon- γ responses to Plasmodium falciparum vaccine candidate antigens decrease in the absence of malaria transmission

Ayieko, C., Ogola, B. S., Ochola, L., Ngwena, G. A. M., Ayodo, G., Hodges, J. S., Noland, G. S. & John, C., 2017, In : PeerJ. 2017, 1, e2855.

Research output: Contribution to journalArticle

2 Scopus citations

Invasive serotype a Haemophilus influenzae infections with a virulence genotype resembling Haemophilus influenzae type b: emerging pathogen in the vaccine era?

Adderson, E. E., Byington, C. L., Spencer, L., Kimball, A., Hindiyeh, M., Carroll, K., Mottice, S., Korgenski, E. K., Christenson, J. C. & Pavia, A. T., Jul 2001, In : Pediatrics. 108, 1, p. E18

Research output: Contribution to journalArticle

Open Access
78 Scopus citations

Lack of mortality in 22 children with sickle cell anemia and severe malarial anemia

Opoka, R. O., Bangirana, P., Idro, R., Shabani, E., Namazzi, R. & John, C. C., Jan 2018, In : Pediatric Blood and Cancer. 65, 1, e26745.

Research output: Contribution to journalArticle

3 Scopus citations

Latent tuberculosis infection in children: A call for revised treatment guidelines

Finnell, S. M. E., Christenson, J. C. & Downs, S. M., Mar 1 2009, In : Pediatrics. 123, 3, p. 816-822 7 p.

Research output: Contribution to journalArticle

16 Scopus citations

Linezolid-associated thrombocytopenia in children with renal impairment

Jones, S. J., Nichols, K. R., DeYoung, H. L., Cox, E. G. & Knoderer, C. A., Jan 1 2015, In : Journal of the Pediatric Infectious Diseases Society. 4, 3, p. 272-275 4 p.

Research output: Contribution to journalArticle

2 Scopus citations

Lipoid pneumonia and Mycobacterium smegmatis

Cox, E. G., Heil, S. A. & Kleiman, M. B., Jan 1 1994, In : Pediatric Infectious Disease Journal. 13, 5, p. 414-415 2 p.

Research output: Contribution to journalArticle

16 Scopus citations

Longevity of genotype-specific immune responses to Plasmodium falciparum merozoite surface protein 1 in Kenyan children from regions of different malaria transmission intensity

Bowman, N. M., Juliano, J. J., Snider, C. J., Kharabora, O., Meshnick, S. R., Vulule, J., John, C. C. & Moormann, A. M., Sep 2016, In : American Journal of Tropical Medicine and Hygiene. 95, 3, p. 580-587 8 p.

Research output: Contribution to journalArticle

2 Scopus citations