Publications 1986 2019

2019

Admission plasma uromodulin and the risk of acute kidney injury in hospitalized patients with cirrhosis: a pilot study

Patidar, K. R., Garimella, P. S., Macedo, E., Slaven, J. E., Ghabril, M. S., Weber, R. E., Anderson, M., Orman, E. S., Nephew, L. D., Desai, A. P., Chalasani, N. P. & El-Achkar, T. M., Oct 1 2019, In : American journal of physiology. Gastrointestinal and liver physiology. 317, 4, p. G447-G452

Research output: Contribution to journalArticle

Uromodulin
Acute Kidney Injury
Fibrosis
Creatinine
Urine

Adrenocorticotropic Hormone in the Treatment of Focal Segmental Glomerulosclerosis Following Kidney Transplantation

Grafals, M. & Sharfuddin, A., Jul 1 2019, In : Transplantation proceedings. 51, 6, p. 1831-1837 7 p.

Research output: Contribution to journalArticle

Open Access
Focal Segmental Glomerulosclerosis
Kidney Transplantation
Adrenocorticotropic Hormone
Gels
Transplants

Ambulatory Blood Pressure Reduction With SGLT-2 Inhibitors: Dose-Response Meta-analysis and Comparative Evaluation With Low-Dose Hydrochlorothiazide

Georgianos, P. I. & Agarwal, R., Apr 1 2019, In : Diabetes care. 42, 4, p. 693-700 8 p.

Research output: Contribution to journalReview article

Sodium-Glucose Transport Proteins
Hydrochlorothiazide
Meta-Analysis
Blood Pressure
Randomized Controlled Trials
1 Citation (Scopus)

Analytical validity of a genotyping assay for use with personalized antihypertensive and chronic kidney disease therapy

Collins, K. S., Pratt, V. M., Stansberry, W. M., Medeiros, E. B., Kannegolla, K., Swart, M., Skaar, T., Chapman, A. B., Decker, B., Moorthi, R. & Eadon, M., Jan 1 2019, In : Pharmacogenetics and Genomics. 29, 1, p. 18-22 5 p.

Research output: Contribution to journalArticle

Chronic Renal Insufficiency
Antihypertensive Agents
Hypertension
Disease Progression
Kidney Diseases
Angiotensin Receptor Antagonists
Angiotensin-Converting Enzyme Inhibitors
Chronic Kidney Failure
Longitudinal Studies
Cohort Studies

Application of physiological shear stress to renal tubular epithelial cells

Ferrell, N., Sandoval, R. M., Molitoris, B., Brakeman, P., Roy, S. & Fissell, W. H., Jan 1 2019, Methods in Cell Biology. Academic Press Inc., (Methods in Cell Biology).

Research output: Chapter in Book/Report/Conference proceedingChapter

Epithelial Cells
Kidney
Lab-On-A-Chip Devices
Kidney Tubules
Nephrons

A simple automated method for continuous fieldwise measurement of microvascular hemodynamics

Clendenon, S. G., Fu, X., Von Hoene, R. A., Clendenon, J. L., Sluka, J. P., Winfree, S., Mang, H., Martinez, M., Filson, A. J., Klaunig, J. E., Glazier, J. A. & Dunn, K., May 1 2019, In : Microvascular Research. 123, p. 7-13 7 p.

Research output: Contribution to journalArticle

Spatio-Temporal Analysis
Hemodynamics
Motion Pictures
Blood Vessels
Spreadsheets

Assessment and management of hypertension among patients on peritoneal dialysis

Vaios, V., Georgianos, P. I., Liakopoulos, V. & Agarwal, R., Feb 7 2019, In : Clinical Journal of the American Society of Nephrology. 14, 2, p. 297-305 9 p.

Research output: Contribution to journalArticle

Peritoneal Dialysis
Hypertension
Renal Dialysis
Dietary Sodium
Renal Replacement Therapy

A stepwise approach to implementing pharmacogenetic testing in the primary care setting

Weitzel, K. W., Duong, B. Q., Arwood, M. J., Owusu-Obeng, A., Abul-Husn, N. S., Bernhardt, B. A., Decker, B., Denny, J. C., Dietrich, E., Gums, J., Madden, E. B., Pollin, T. I., Wu, R. R., Haga, S. B. & Horowitz, C. R., Jan 1 2019, In : Pharmacogenomics. 20, 15, p. 1103-1112 10 p.

Research output: Contribution to journalReview article

Primary Health Care
Pharmacogenetics
Genomics
National Human Genome Research Institute (U.S.)
Patient Education

Automatic segmentation of intravital fluorescence microscopy images by K-means clustering of FLIM phasors

Zhang, Y., Hato, T., Dagher, P., Nichols, E. L., Smith, C. J., Dunn, K. & Howard, S. S., Aug 15 2019, In : Optics Letters. 44, 16, p. 3928-3931 4 p.

Research output: Contribution to journalArticle

microscopy
life (durability)
fluorescence
marking
machine learning

A Versatile, Portable Intravital Microscopy Platform for Studying Beta-cell Biology In Vivo

Reissaus, C. A., Piñeros, A. R., Twigg, A. N., Orr, K. S., Conteh, A. M., Martinez, M. M., Kamocka, M., Day, R., Tersey, S. A., Mirmira, R., Dunn, K. & Linnemann, A., Dec 1 2019, In : Scientific Reports. 9, 1, 8449.

Research output: Contribution to journalArticle

Open Access
Biosensing Techniques
Cell Biology
Cell Physiological Phenomena
Aptitude
Calcium Signaling
5 Citations (Scopus)

Bacterial sepsis triggers an antiviral response that causes translation shutdown

Hato, T., Maier, B., Syed, F., Myslinski, J., Zollman, A., Plotkin, Z., Eadon, M. & Dagher, P., Jan 2 2019, In : Journal of Clinical Investigation. 129, 1, CI123284.

Research output: Contribution to journalArticle

Antiviral Agents
Sepsis
Eukaryotic Initiation Factor-2
Eukaryotic Initiation Factors
Kidney

Bariatric surgery as a renoprotective intervention

Friedman, A. & Cohen, R. V., Jan 1 2019, (Accepted/In press) In : Current Opinion in Nephrology and Hypertension.

Research output: Contribution to journalReview article

Bariatric Surgery
Chronic Renal Insufficiency
Kidney
Type 2 Diabetes Mellitus
Hypertension

Beyond Biomarkers: Machine Learning in Diagnosing Acute Kidney Injury

Molitoris, B., May 1 2019, In : Mayo Clinic Proceedings. 94, 5, p. 748-750 3 p.

Research output: Contribution to journalEditorial

Acute Kidney Injury
Biomarkers
Machine Learning
1 Citation (Scopus)

Canagliflozin and Cardiovascular and Renal Outcomes in Type 2 Diabetes Mellitus and Chronic Kidney Disease in Primary and Secondary Cardiovascular Prevention Groups

Mahaffey, K. W., Jardine, M. J., Bompoint, S., Cannon, C. P., Neal, B., Heerspink, H. J. L., Charytan, D. M., Edwards, R., Agarwal, R., Bakris, G., Bull, S., Capuano, G., de Zeeuw, D., Greene, T., Levin, A., Pollock, C., Sun, T., Wheeler, D. C., Yavin, Y., Zhang, H. & 4 others, Zinman, B., Rosenthal, N., Brenner, B. M. & Perkovic, V., Aug 27 2019, In : Circulation. 140, 9, p. 739-750 12 p.

Research output: Contribution to journalArticle

Open Access
Secondary Prevention
Chronic Renal Insufficiency
Type 2 Diabetes Mellitus
Kidney
Primary Prevention
131 Citations (Scopus)

Canagliflozin and renal outcomes in type 2 diabetes and nephropathy

for the CREDENCE Trial Investigators, Jun 13 2019, In : New England Journal of Medicine. 380, 24, p. 2295-2306 12 p.

Research output: Contribution to journalArticle

Type 2 Diabetes Mellitus
Kidney
Confidence Intervals
Chronic Kidney Failure
Placebos
1 Citation (Scopus)

Cardiovascular disease in the kidney transplant recipient: epidemiology, diagnosis and management strategies

Rangaswami, J., Mathew, R. O., Parasuraman, R., Tantisattamo, E., Lubetzky, M., Rao, S., Yaqub, M., Birdwell, K. A., Bennett, W., Dalal, P., Kapoor, R., Lerma, E. V., Lerman, M., McCormick, N., Bangalore, S., McCullough, P. A. & Dadhania, D. M., May 1 2019, In : Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association. 34, 5, p. 760-773 14 p.

Research output: Contribution to journalArticle

Open Access
Kidney Transplantation
Epidemiology
Cardiovascular Diseases
Kidney
Chronic Kidney Failure
8 Citations (Scopus)

Cardiovascular outcome trials in patients with chronic kidney disease: Challenges associated with selection of patients and endpoints

Rossignol, P., Agarwal, R., Canaud, B., Charney, A., Chatellier, G., Craig, J. C., Cushman, W. C., Gansevoort, R. T., Fellström, B., Garza, D., Guzman, N., Holtkamp, F. A., London, G. M., Massy, Z. A., Mebazaa, A., Mol, P. G. M., Pfeffer, M. A., Rosenberg, Y., Ruilope, L. M., Seltzer, J. & 15 others, Shah, A. M., Shah, S., Singh, B., Stefánsson, B. V., Stockbridge, N., Stough, W. G., Thygesen, K., Walsh, M., Wanner, C., Warnock, D. G., Wilcox, C. S., Wittes, J., Pitt, B., Thompson, A. & Zannad, F., Mar 14 2019, In : European Heart Journal. 40, 11, p. 880-886 7 p.

Research output: Contribution to journalArticle

Chronic Renal Insufficiency
Patient Selection
Cardiovascular Diseases
Kidney
Chronic Kidney Failure

Caring for individuals with hypertension in CKD, especially those with low education

Agarwal, R., Oct 1 2019, In : Kidney international. 96, 4, p. 820-822 3 p.

Research output: Contribution to journalComment/debate

Hypertension
Education
Spironolactone
Albuminuria
Potassium

Center-extraction-based three dimensional nuclei instance segmentation of fluorescence microscopy images

Ho, D. J., Han, S., Fu, C., Salama, P., Dunn, K. W. & Delp, E. J., May 2019, 2019 IEEE EMBS International Conference on Biomedical and Health Informatics, BHI 2019 - Proceedings. Institute of Electrical and Electronics Engineers Inc., 8834516. (2019 IEEE EMBS International Conference on Biomedical and Health Informatics, BHI 2019 - Proceedings).

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Fluorescence microscopy
Fluorescence Microscopy
Microscopic examination
Tissue
Microscopy

Characterizing Dysgeusia in Hemodialysis Patients

Fitzgerald, C., Wiese, G., Moorthi, R., Moe, S., Hill Gallant, K. & Running, C. A., Mar 11 2019, In : Chemical Senses. 44, 3, p. 165-171 7 p.

Research output: Contribution to journalArticle

Dysgeusia
Renal Dialysis
Dialysis
Taste Perception
Sodium Glutamate
2 Citations (Scopus)

Chronic kidney disease and peripheral nerve function in the Health, Aging and Body Composition Study

Moorthi, R., Doshi, S., Fried, L. F., Moe, S., Sarnak, M. J., Satterfield, S., Schwartz, A. V., Shlipak, M., Lange-Maia, B. S., Harris, T. B., Newman, A. B. & Strotmeyer, E. S., Apr 1 2019, In : Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association. 34, 4, p. 625-632 8 p.

Research output: Contribution to journalArticle

Body Composition
Chronic Renal Insufficiency
Peripheral Nerves
Health
Odds Ratio

Circulating uromodulin inhibits systemic oxidative stress by inactivating the TRPM2 channel

LaFavers, K. A., Macedo, E., Garimella, P. S., Lima, C., Khan, S., Myslinski, J., McClintick, J., Witzmann, F. A., Winfree, S., Phillips, C. L., Hato, T., Dagher, P. C., Wu, X. R., El-Achkar, T. M. & Micanovic, R., Oct 2 2019, In : Science translational medicine. 11, 512

Research output: Contribution to journalArticle

Uromodulin
Oxidative Stress
Acute Kidney Injury
Protein Deficiency
Reactive Oxygen Species
2 Citations (Scopus)
Open Access
Clinical Pharmacology
Antihypertensive Agents
Hypertension
Sodium Chloride Symporter Inhibitors
Adrenergic Antagonists

Comparison of risk factors for pediatric kidney stone formation: The effects of sex

Schwaderer, A. L., Raina, R., Khare, A., Safadi, F., Moe, S. & Kusumi, K., Jan 1 2019, In : Frontiers in Pediatrics. 7, FEB, 32.

Research output: Contribution to journalArticle

Open Access
Kidney Calculi
Pediatrics
International Classification of Diseases
Pyuria
Flank Pain

Development and Validation of a Model to Predict Acute Kidney Injury in Hospitalized Patients With Cirrhosis

Patidar, K. R., Xu, C., Shamseddeen, H., Cheng, Y. W., Ghabril, M. S., Mukthinuthalapati, V. V. P. K., Fricker, Z. P., Akinyeye, S., Nephew, L. D., Desai, A. P., Anderson, M., El-Achkar, T. M., Chalasani, N. P. & Orman, E. S., Sep 1 2019, In : Clinical and translational gastroenterology. 10, 9, p. e00075

Research output: Contribution to journalArticle

Open Access
Acute Kidney Injury
Fibrosis
End Stage Liver Disease
International Normalized Ratio
Leukocyte Count
1 Citation (Scopus)

Does an apple (or many) each day, keep mortality away?

Moorthi, R., Feb 7 2019, In : Clinical Journal of the American Society of Nephrology. 14, 2, p. 180-181 2 p.

Research output: Contribution to journalEditorial

Malus
Mortality

Drug-gene and drug-drug interactions associated with tramadol and codeine therapy in the INGENIOUS trial

Fulton, C. R., Zang, Y., Desta, Z., Rosenman, M., Holmes, A., Decker, B., Zhang, Y., T Callaghan, J., Pratt, V. M., Levy, K., Gufford, B. T., Dexter, P., Skaar, T. & Eadon, M., Apr 1 2019, In : Pharmacogenomics. 20, 6, p. 397-408 12 p.

Research output: Contribution to journalArticle

Tramadol
Codeine
Drug Interactions
Cytochrome P-450 CYP2D6
Pharmaceutical Preparations
1 Citation (Scopus)

Effect of ovariectomy on the progression of chronic kidney disease-mineral bone disorder (CKD-MBD) in female Cy/+ rats

Vorland, C. J., Lachcik, P. J., Swallow, E. A., Metzger, C. E., Allen, M., Chen, X. N., Moe, S. & Hill Gallant, K. M., May 28 2019, In : Scientific reports. 9, 1, 1 p.

Research output: Contribution to journalArticle

Open Access
Chronic Kidney Disease-Mineral and Bone Disorder
Ovariectomy
Porosity
Kidney Diseases
Phosphorus

Fibroblast Growth Factor 23 Genotype and Cardiovascular Disease in Patients Undergoing Hemodialysis

Schwantes-An, T. H., Liu, S., Stedman, M., Decker, B., Wetherill, L., Edenberg, H., Vatta, M., Foroud, T., Chertow, G. M. & Moe, S., Jan 1 2019, (Accepted/In press) In : American Journal of Nephrology. p. 125-132 8 p.

Research output: Contribution to journalArticle

Renal Dialysis
Cardiovascular Diseases
Genotype
Heart Failure
Mortality

Fluorescent Imaging and Microscopy for Dynamic Processes in Rats

Sandoval, R. M., Molitoris, B. & Palygin, O., Jan 1 2019, Methods in Molecular Biology. Humana Press Inc., p. 151-175 25 p. (Methods in Molecular Biology; vol. 2018).

Research output: Chapter in Book/Report/Conference proceedingChapter

Microscopy
Photons
Kidney
Genetically Modified Animals
Translational Medical Research

Hypertension in chronic kidney disease: Nephrology Dialysis Transplantation notable 2017 advances

Georgianos, P. I. & Agarwal, R., Jan 1 2019, In : Nephrology Dialysis Transplantation. 34, 1, p. 1-4 4 p.

Research output: Contribution to journalReview article

Open Access
Nephrology
Chronic Renal Insufficiency
Dialysis
Transplantation
Hypertension
2 Citations (Scopus)

Increased FGF23 protects against detrimental cardio-renal consequences during elevated blood phosphate in CKD

Clinkenbeard, E. L., Noonan, M. L., Thomas, J. C., Ni, P., Hum, J. M., Aref, M., Swallow, E. A., Moe, S., Allen, M. & White, K., Feb 21 2019, In : JCI insight. 4, 4

Research output: Contribution to journalArticle

Chronic Renal Insufficiency
Phosphates
Adenine
Kidney
Caseins

Intravenous iron and maintenance hemodialysis

Agarwal, R., Jun 13 2019, In : New England Journal of Medicine. 380, 24, p. E46

Research output: Contribution to journalLetter

Renal Dialysis
Iron
Maintenance
3 Citations (Scopus)

KDOQI US Commentary on the 2017 ACC/AHA Hypertension Guideline

Kramer, H. J., Townsend, R. R., Griffin, K., Flynn, J. T., Weiner, D. E., Rocco, M. V., Choi, M. J., Weir, M. R., Chang, T. I., Agarwal, R. & Beddhu, S., Apr 1 2019, In : American Journal of Kidney Diseases. 73, 4, p. 437-458 22 p.

Research output: Contribution to journalArticle

American Heart Association
Kidney Diseases
Cardiology
Guidelines
Hypertension

Lack of Benefit and Potential Harm of Induction Therapy in Simultaneous Liver-Kidney Transplants

Ekser, B., Kubal, C. A., Fridell, J. A., Sharfuddin, A., Taber, T., Lacerda, M. A., Ghabril, M., Powelson, J. A. & Goggins, W. C., Jan 1 2019, In : Liver Transplantation.

Research output: Contribution to journalLetter

Transplants
Kidney
Liver
Therapeutics
Panniculitis
Allografts
Pancreas
Transplants
Kidney

Nuclei counting in microscopy images with three dimensional generative adversarial networks

Han, S., Lee, S., Fu, C., Salama, P., Dunn, K. & Delp, E. J., Jan 1 2019, Medical Imaging 2019: Image Processing. Landman, B. A., Angelini, E. D., Angelini, E. D. & Angelini, E. D. (eds.). SPIE, 109492Y. (Progress in Biomedical Optics and Imaging - Proceedings of SPIE; vol. 10949).

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Three-Dimensional Imaging
Fluorescence microscopy
Fluorescence Microscopy
Microscopy
Microscopic examination
Chronic Renal Insufficiency
Blood Vessels
Perfusion
Parathyroid Hormone
Therapeutics

Patiromer versus placebo to enable spironolactone use in patients with resistant hypertension and chronic kidney disease (AMBER): a phase 2, randomised, double-blind, placebo-controlled trial

Agarwal, R., Rossignol, P., Romero, A., Garza, D., Mayo, M. R., Warren, S., Ma, J., White, W. B. & Williams, B., Oct 26 2019, In : The Lancet. 394, 10208, p. 1540-1550 11 p.

Research output: Contribution to journalArticle

Spironolactone
Chronic Renal Insufficiency
Placebos
Hypertension
Hyperkalemia

Prediction of Nephropathy in Type 2 Diabetes: An Analysis of the ACCORD Trial Applying Machine Learning Techniques

Rodriguez-Romero, V., Bergstrom, R. F., Decker, B., Lahu, G., Vakilynejad, M. & Bies, R., Jan 1 2019, In : Clinical and translational science.

Research output: Contribution to journalArticle

Open Access
Diabetic Nephropathies
Medical problems
Glomerular Filtration Rate
Type 2 Diabetes Mellitus
Learning systems

Rehospitalization Rates in Hypertensive Emergency

Agarwal, R., Jan 1 2019, In : Hypertension (Dallas, Tex. : 1979). 73, 1, p. 49-51 3 p.

Research output: Contribution to journalEditorial

Emergencies

Skeletal levels of bisphosphonate in the setting of chronic kidney disease are independent of remodeling rate and lower with fractionated dosing

Swallow, E. A., Aref, M. W., Metzger, C. E., Sacks, S., Lehmkuhler, D. R., Chen, X. N., Hammond, M. A., Territo, P., Nickolas, T. L., Moe, S. & Allen, M., Oct 1 2019, In : Bone. 127, p. 419-426 8 p.

Research output: Contribution to journalArticle

zoledronic acid
Diphosphonates
Chronic Renal Insufficiency
Animal Models
Bone and Bones

Systolic and diastolic hypertension among patients on hemodialysis: Musings on volume overload, arterial stiffness, and erythropoietin

Georgianos, P. I. & Agarwal, R., Jan 1 2019, (Accepted/In press) In : Seminars in Dialysis.

Research output: Contribution to journalReview article

Vascular Stiffness
Erythropoietin
Renal Dialysis
Hypertension
Antihypertensive Agents

Systolic Blood Pressure Intervention Trial and Statins, a Story of Statistical Interaction

Tu, W. & Agarwal, R., Jan 1 2019, In : American Journal of Nephrology. p. 294-296 3 p.

Research output: Contribution to journalReview article

Open Access
Hydroxymethylglutaryl-CoA Reductase Inhibitors
Blood Pressure
3 Citations (Scopus)

Targeting the hepcidin–ferroportin pathway in anaemia of chronic kidney disease

Sheetz, M., Barrington, P., Callies, S., Berg, P. H., McColm, J., Marbury, T., Decker, B., Dyas, G. L., Truhlar, S. M. E., Benschop, R., Leung, D., Berg, J. & Witcher, D. R., Jan 1 2019, In : British Journal of Clinical Pharmacology.

Research output: Contribution to journalArticle

Chronic Renal Insufficiency
Anemia
Hepcidins
Iron
Ferritins

Tester and testing procedure influence clinically determined gait speed

Warden, S. J., Kemp, A. C., Liu, Z. & Moe, S., Oct 1 2019, In : Gait and Posture. 74, p. 83-86 4 p.

Research output: Contribution to journalArticle

Walking Speed
Research Personnel
Morbidity
Mortality
Research

The archaeal Dps nanocage targets kidney proximal tubules via glomerular filtration

Uchida, M., Maier, B., Waghwani, H. K., Selivanovitch, E., Louise Pay, S., Avera, J., Jun Yun, E., Sandoval, R. M., Molitoris, B., Zollman, A., Douglas, T. & Hato, T., Sep 3 2019, In : Journal of Clinical Investigation. 129, 9, p. 3941-3951 11 p.

Research output: Contribution to journalArticle

Open Access
Proximal Kidney Tubule
Glomerular Filtration Barrier
Endocytosis
Proteins
Antioxidants

The Association Between Kidney Disease and Diabetes Remission in Bariatric Surgery Patients With Type 2 Diabetes

Friedman, A., Wang, J., Wahed, A. S., Docherty, N. G., Fennern, E., Pomp, A., Purnell, J. Q., le Roux, C. W. & Wolfe, B., Jan 1 2019, In : American Journal of Kidney Diseases.

Research output: Contribution to journalArticle

Bariatric Surgery
Kidney Diseases
Chronic Renal Insufficiency
Type 2 Diabetes Mellitus
Glomerular Filtration Rate

The case for a bariatric-centered approach to CKD care

Friedman, A., Feb 7 2019, In : Clinical Journal of the American Society of Nephrology. 14, 2, p. 291-293 3 p.

Research output: Contribution to journalArticle

Open Access
Bariatrics