Publications 1986 2020

29 Citations (Scopus)
Sodium Fluoride
Guanine Nucleotides
Pertussis Toxin
Epoprostenol
Phosphatidylinositols
85 Citations (Scopus)

Soluble thrombomodulin protects ischemic kidneys

Sharfuddin, A., Sandoval, R. M., Berg, D. T., McDougal, G. E., Campos-Bilderback, S., Phillips, C., Jones, B. E., Gupta, A., Grinnell, B. W. & Molitoris, B., Mar 2009, In : Journal of the American Society of Nephrology. 20, 3, p. 524-534 11 p.

Research output: Contribution to journalArticle

Thrombomodulin
Kidney
Protein C
Acute Kidney Injury
Microscopy
13 Citations (Scopus)

Soluble thrombomodulin reduces inflammation and prevents microalbuminuria induced by chronic endothelial activation in transgenic mice

Rajashekhar, G., Gupta, A., Marin, A., Friedrich, J., Willuweit, A., Berg, D. T., Cramer, M. S., Sandusky, G., Sutton, T., Basile, D., Grinnell, B. W. & Clauss, M., Mar 2012, In : American Journal of Physiology - Renal Physiology. 302, 6

Research output: Contribution to journalArticle

Thrombomodulin
Transgenic Mice
Inflammation
Chronic Renal Insufficiency
Chemokines
3 Citations (Scopus)

Solute control in acute renal failure: Prescription and delivery of adequate extracorporeal therapy

Clark, W. R., Mueller, B. A., Kraus, M. & Macias, W. L., Mar 1996, In : Seminars in Dialysis. 9, 2, p. 133-139 7 p.

Research output: Contribution to journalArticle

Acute Kidney Injury
Prescriptions
Therapeutics

Spatial Temporal Analysis of Fieldwise Flow in Microvasculature

Clendenon, S. G., Fu, X., Von Hoene, R. A., Clendenon, J. L., Sluka, J. P., Winfree, S., Mang, H., Martinez, M., Filson, A., Klaunig, J. E., Glazier, J. A. & Dunn, K. W., Nov 18 2019, In : Journal of visualized experiments : JoVE. 153

Research output: Contribution to journalArticle

Spatio-Temporal Analysis
Capillary flow
Microvessels
Flow velocity
Blood

Special nutritional needs of chronic kidney disease and end-stage renal disease patients: Rationale for the use of plant-based diets

Moorthi, R. & Moe, S., Jan 1 2017, Dietary Phosphorus: Health, Nutrition, and Regulatory Aspects. CRC Press, p. 235-246 12 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

Chronic Renal Insufficiency
Chronic Kidney Failure
Phosphates
Diet
Kidney Diseases
18 Citations (Scopus)

Starting a home hemodialysis program

Moran, J. & Kraus, M., Jan 2007, In : Seminars in Dialysis. 20, 1, p. 35-39 5 p.

Research output: Contribution to journalArticle

Home Hemodialysis
Dialysis
Patient Selection
Chronic Kidney Failure
Prescriptions
44 Citations (Scopus)

Statin induced proteinuria: Renal injury or renoprotection?

Agarwal, R., Sep 2004, In : Journal of the American Society of Nephrology. 15, 9, p. 2502-2503 2 p.

Research output: Contribution to journalArticle

Hydroxymethylglutaryl-CoA Reductase Inhibitors
Kidney Diseases
Proteinuria
Kidney
Wounds and Injuries
52 Citations (Scopus)

Statistical tests for measures of colocalization in biological microscopy

Mcdonald, J. H. & Dunn, K., Dec 2013, In : Journal of Microscopy. 252, 3, p. 295-302 8 p.

Research output: Contribution to journalArticle

Microscopy
Students
Statistical Data Interpretation
Spatial Analysis
Random Allocation
2 Citations (Scopus)

Steroid-free three-drug maintenance regimen for pancreas transplant alone: Comparison of induction with rabbit antithymocyte globulin +/− rituximab

Fridell, J. A., Mangus, R., Chen, J. M., Taber, T., Cabrales, A. E., Sharfuddin, A., Yaqub, M. & Powelson, J. A., Dec 1 2018, In : American Journal of Transplantation. 18, 12, p. 3000-3006 7 p.

Research output: Contribution to journalArticle

Antilymphocyte Serum
Pancreas
Steroids
Maintenance
Rabbits
12 Citations (Scopus)

Strategies and feasibility of hypertension control in a prevalent hemodialysis cohort

Agarwal, R., 2000, In : Clinical Nephrology. 53, 5, p. 344-353 10 p.

Research output: Contribution to journalArticle

Renal Dialysis
Dialysis
Blood Pressure
Hypertension
Antihypertensive Agents
8 Citations (Scopus)

Strategies for successful patient oriented research: why did I (not) get funded?

Agarwal, R., Chertow, G. M. & Mehta, R. L., Mar 2006, In : Clinical Journal of the American Society of Nephrology. 1, 2, p. 340-343 4 p.

Research output: Contribution to journalArticle

Organized Financing
Research
Mentors
Ownership
Sample Size
21 Citations (Scopus)

Stress response proteins and renal ischemia

Kelly, K., Jun 2002, In : Minerva Urologica e Nefrologica. 54, 2, p. 81-91 11 p.

Research output: Contribution to journalArticle

Heat-Shock Proteins
Ischemia
Kidney
Ischemic Preconditioning
Peptides
15 Citations (Scopus)

Studies of renal injury. I. Gentamicin toxicity and expression of basolateral transporters

Dominguez, J., Hale, C. C. & Qulali, M., 1996, In : American Journal of Physiology - Renal Physiology. 270, 2 PART 2

Research output: Contribution to journalArticle

Gentamicins
Kidney
Messenger RNA
Wounds and Injuries
Proteins
20 Citations (Scopus)

Studies of renal injury. II. Activation of the glucose transporter 1 (GLUT1) gene and glycolysis in LLC-PK1 cells under Ca2+ stress

Dominguez, J., Song, B., Liu-Chen, S., Qulali, M., Howard, R., Lee, C-H. & McAteer, J., Jul 15 1996, In : Journal of Clinical Investigation. 98, 2, p. 395-404 10 p.

Research output: Contribution to journalArticle

LLC-PK1 Cells
Facilitative Glucose Transport Proteins
Glycolysis
Kidney
Wounds and Injuries
62 Citations (Scopus)

Studies of renal injury III: Lipid-induced nephropathy in type II diabetes

Dominguez, J., Tang, N., Xu, W., Evan, A., Siakotos, A. N., Agarwal, R., Walsh, J., Deeg, M., Pratt, J. H., March, K. L., Monnier, V. M., Weiss, M. F., Baynes, J. W. & Peterson, R., 2000, In : Kidney International. 57, 1, p. 92-104 13 p.

Research output: Contribution to journalArticle

Type 2 Diabetes Mellitus
Kidney
Wounds and Injuries
Carbohydrates
Renal Insufficiency
8 Citations (Scopus)

Studies of renal injury IV: The GLUT1 gene protects renal cells from cyclosporine A toxicity

Dominguez, J., Soleimani, M. & Batiuk, T., 2002, In : Kidney International. 62, 1, p. 127-136 10 p.

Research output: Contribution to journalArticle

Cyclosporine
Kidney
Wounds and Injuries
Glucose
Genes
78 Citations (Scopus)

Study of blood flow impact on growth of thrombi using a multiscale model

Xu, Z., Chen, N., Shadden, S. C., Marsden, J. E., Kamocka, M., Rosen, E. & Alber, M., 2009, In : Soft Matter. 5, 4, p. 769-779 11 p.

Research output: Contribution to journalArticle

multiscale models
blood flow
platelets
Blood
Platelets
7 Citations (Scopus)

Subcutaneous nerve activity and mechanisms of sudden death in a rat model of chronic kidney disease

Zhao, Y., Chen, X. N., Shirazi, J. T., Shen, C., Lin, S-F., Fishbein, M. C., Moe, S. & Chen, P-S., 2016, (Accepted/In press) In : Heart Rhythm.

Research output: Contribution to journalArticle

Sudden Death
Chronic Renal Insufficiency
Heart Rate
Chemical Sympathectomy
Atrioventricular Block
2 Citations (Scopus)

Subgroup analyses in nephrology clinical trials

Fishbane, S., Shah, H. H., Kataria, A., Shirazian, S. & Agarwal, R., Nov 7 2012, In : Clinical Journal of the American Society of Nephrology. 7, 11, p. 1872-1876 5 p.

Research output: Contribution to journalArticle

Amlodipine
Statistical Data Interpretation
Nephrology
Heart Failure
Clinical Trials

Sudden cardiac death in patients undergoing dialysis: More than a single toxin

Moe, S. M., Jan 1 2018, (Accepted/In press) In : Heart Rhythm.

Research output: Contribution to journalArticle

Sudden Cardiac Death
Dialysis
5 Citations (Scopus)

Sulforaphane suppresses the growth of glioblastoma cells, glioblastoma stem cell-like spheroids, and tumor xenografts through multiple cell signaling pathways

Bijangi-Vishehsaraei, K., Saadatzadeh, M. R., Wang, H., Nguyen, A., Kamocka, M., Cai, W., Cohen-Gadol, A., Halum, S. L., Sarkaria, J. N., Pollok, K. & Safa, A., Dec 1 2017, In : Journal of Neurosurgery. 127, 6, p. 1219-1230 12 p.

Research output: Contribution to journalArticle

Glioblastoma
Heterografts
Stem Cells
Growth
Neoplasms
86 Citations (Scopus)

Supervised atenolol therapy in the management of hemodialysis hypertension

Agarwal, R., 1999, In : Kidney International. 55, 4, p. 1528-1535 8 p.

Research output: Contribution to journalArticle

Atenolol
Renal Dialysis
Blood Pressure
Hypertension
Antihypertensive Agents
31 Citations (Scopus)

Surface membrane polarity of proximal tubular cells: Alterations as a basis for malfunction

Molitoris, B. & Wagner, M., 1996, In : Kidney International. 49, 6, p. 1592-1597 6 p.

Research output: Contribution to journalArticle

Membranes
Actin Cytoskeleton
Membrane Proteins
Cell-Matrix Junctions
Membrane Lipids
23 Citations (Scopus)

Survivin-induced abnormal ploidy contributes to cystic kidney and aneurysm formation

Abou Alaiwi, W. A., Muntean, B. S., Ratnam, S., Joe, B., Liu, L., Booth, R. L., Rodriguez, I., Herbert, B-S., Bacallao, R., Fruttiger, M., Mak, T. W., Zhou, J. & Nauli, S. M., Feb 11 2014, In : Circulation. 129, 6, p. 660-672 13 p.

Research output: Contribution to journalArticle

Cystic Kidney Diseases
Ploidies
Aneurysm
Cilia
Polycystic Kidney Diseases

Systolic and diastolic hypertension among patients on hemodialysis: Musings on volume overload, arterial stiffness, and erythropoietin

Georgianos, P. I. & Agarwal, R., Jan 1 2019, (Accepted/In press) In : Seminars in Dialysis.

Research output: Contribution to journalReview article

Vascular Stiffness
Erythropoietin
Renal Dialysis
Hypertension
Antihypertensive Agents

Systolic Blood Pressure Intervention Trial and Statins, a Story of Statistical Interaction

Tu, W. & Agarwal, R., Jan 1 2019, In : American Journal of Nephrology. p. 294-296 3 p.

Research output: Contribution to journalReview article

Open Access
Hydroxymethylglutaryl-CoA Reductase Inhibitors
Blood Pressure
35 Citations (Scopus)

Systolic Hypertension in Hemodialysis Patients

Agarwal, R., May 2003, In : Seminars in Dialysis. 16, 3, p. 208-213 6 p.

Research output: Contribution to journalArticle

Renal Dialysis
Blood Pressure
Hypertension
Mortality
Dialysis
8 Citations (Scopus)

Tamm-horsfall protein/uromodulin deficiency elicits tubular compensatory responses leading to hypertension and hyperuricemia

Liu, Y., Goldfarb, D. S., Ashkar (El-Achkar), T., Lieske, J. C. & Wu, X. R., Jun 1 2018, In : American Journal of Physiology - Renal Physiology. 314, 6, p. F1062-F1076

Research output: Contribution to journalArticle

Uromodulin
Protein Deficiency
Hyperuricemia
Knockout Mice
Sodium-Potassium-Chloride Symporters
38 Citations (Scopus)

Tamm-horsfall protein-deficient thick ascending limbs promote injury to neighboring S3 segments in an MIP-2-dependent mechanism

Ashkar (El-Achkar), T., Mccracken, R., Rauchman, M., Heitmeier, M. R., Al-Aly, Z., Dagher, P. & Wu, X. R., Apr 1 2011, In : American Journal of Physiology - Renal Physiology. 300, 4, p. 999-1007 9 p.

Research output: Contribution to journalArticle

Uromodulin
Chemokine CXCL2
Extremities
Wounds and Injuries
Inflammation
90 Citations (Scopus)
Uromodulin
Toll-Like Receptor 4
Inflammation
Kidney
Wounds and Injuries
11 Citations (Scopus)

Tamm-horsfall protein regulates granulopoiesis and systemic neutrophil homeostasis

Micanovic, R., Chitteti, B. R., Dagher, P., Srour, E., Khan, S., Hato, T., Lyle, A., Tong, Y., Wu, X. R. & Ashkar (El-Achkar), T., Sep 1 2015, In : Journal of the American Society of Nephrology. 26, 9, p. 2172-2182 11 p.

Research output: Contribution to journalArticle

Uromodulin
Neutrophils
Homeostasis
Kidney
Interleukin-23
10 Citations (Scopus)

Tamm-Horsfall protein regulates mononuclear phagocytes in the kidney

Micanovic, R., Khan, S., Janosevic, D., Lee, M. E., Hato, T., Srour, E., Winfree, S., Ghosh, J., Tong, Y., Rice, S. E., Dagher, P., Wu, X. R. & Ashkar (El-Achkar), T., Mar 1 2018, In : Journal of the American Society of Nephrology. 29, 3, p. 841-856 16 p.

Research output: Contribution to journalArticle

Uromodulin
Phagocytes
Kidney
Reperfusion Injury
Macrophages
42 Citations (Scopus)

Tamm-Horsfall protein translocates to the basolateral domain of thick ascending limbs, interstitium, and circulation during recovery from acute kidney injury

Ashkar (El-Achkar), T., Mccracken, R., Liu, Y., Heitmeier, M. R., Bourgeois, S., Ryerse, J. & Wu, X. R., 2013, In : American Journal of Physiology - Renal Physiology. 304, 8, p. 1066-1075 10 p.

Research output: Contribution to journalArticle

Uromodulin
Acute Kidney Injury
Extremities
Reperfusion
Ischemia
4 Citations (Scopus)

Targeting the hepcidin–ferroportin pathway in anaemia of chronic kidney disease

Sheetz, M., Barrington, P., Callies, S., Berg, P. H., McColm, J., Marbury, T., Decker, B., Dyas, G. L., Truhlar, S. M. E., Benschop, R., Leung, D., Berg, J. & Witcher, D. R., Jan 1 2019, In : British Journal of Clinical Pharmacology.

Research output: Contribution to journalArticle

Chronic Renal Insufficiency
Anemia
Hepcidins
Iron
Ferritins
11 Citations (Scopus)

Techniques to study nephron function: Microscopy and imaging

Molitoris, B. & Sandoval, R. M., May 2009, In : Pflugers Archiv European Journal of Physiology. 458, 1, p. 203-209 7 p.

Research output: Contribution to journalArticle

Fluorophores
Nephrons
Microscopy
Microscopic examination
Animals
56 Citations (Scopus)

Technology Insight: Biomarker development in acute kidney injury - What can we anticipate?

Molitoris, B., Melnikov, V. Y., Okusa, M. D. & Himmelfarb, J., Mar 2008, In : Nature Clinical Practice Nephrology. 4, 3, p. 154-165 12 p.

Research output: Contribution to journalArticle

Acute Kidney Injury
Biomarkers
Technology
Early Diagnosis
Blood Urea Nitrogen
6 Citations (Scopus)

Temperature sensitivity and fluorescence detection

Agarwal, R., Jan 2008, In : Journal of Separation Science. 31, 1, p. 128-132 5 p.

Research output: Contribution to journalArticle

Fluorescence
Temperature
Detectors
Malondialdehyde
Trace analysis

Tester and testing procedure influence clinically determined gait speed

Warden, S. J., Kemp, A. C., Liu, Z. & Moe, S., Oct 1 2019, In : Gait and Posture. 74, p. 83-86 4 p.

Research output: Contribution to journalArticle

Walking Speed
Research Personnel
Morbidity
Mortality
Research

Testing effects of signal transduction pathways on cadherin junctional complex assembly using quantitative image analysis

Gopalakrishnan, S., Dunn, K. & Marrs, J. A., Jul 1 2003, In : Methods. 30, 3, p. 218-227 10 p.

Research output: Contribution to journalArticle

Signal transduction
Cadherins
Image analysis
Signal Transduction
Molecules
4 Citations (Scopus)

The antibiotic gentamicin inhibits specific protein trafficking functions of the arf1/2 family of GTPases

Lin, L., Wagner, M., Cocklin, R., Kuzma, A., Harrington, M., Molitoris, B. & Goebl, M., Jan 2011, In : Antimicrobial Agents and Chemotherapy. 55, 1, p. 246-254 9 p.

Research output: Contribution to journalArticle

GTP Phosphohydrolases
Protein Transport
Gentamicins
Anti-Bacterial Agents
Translational Peptide Chain Termination
1 Citation (Scopus)

The archaeal Dps nanocage targets kidney proximal tubules via glomerular filtration

Uchida, M., Maier, B., Waghwani, H. K., Selivanovitch, E., Louise Pay, S., Avera, J., Jun Yun, E., Sandoval, R. M., Molitoris, B., Zollman, A., Douglas, T. & Hato, T., Sep 3 2019, In : Journal of Clinical Investigation. 129, 9, p. 3941-3951 11 p.

Research output: Contribution to journalArticle

Open Access
Proximal Kidney Tubule
Glomerular Filtration Barrier
Endocytosis
Proteins
Antioxidants

The Association Between Kidney Disease and Diabetes Remission in Bariatric Surgery Patients With Type 2 Diabetes

Friedman, A., Wang, J., Wahed, A. S., Docherty, N. G., Fennern, E., Pomp, A., Purnell, J. Q., le Roux, C. W. & Wolfe, B., Jan 1 2019, In : American Journal of Kidney Diseases.

Research output: Contribution to journalArticle

Bariatric Surgery
Kidney Diseases
Chronic Renal Insufficiency
Type 2 Diabetes Mellitus
Glomerular Filtration Rate
1 Citation (Scopus)

The Author Replies

Agarwal, R., Dec 1 2015, In : Kidney International. 88, 6, p. 1446-1447 2 p.

Research output: Contribution to journalArticle

The authors reply

Drueke, T. B. & Moe, S., May 2010, In : Kidney International. 77, 10, p. 928-929 2 p.

Research output: Contribution to journalArticle

The authors reply

Ott, S. M., Moe, S. & Drüeke, T. B., Dec 2010, In : Kidney International. 78, 11, p. 1186 1 p.

Research output: Contribution to journalArticle

The Authors Reply

Ott, S. M., Drueke, T. B. & Moe, S., Sep 1 2011, In : Kidney International. 80, 5, p. 554 1 p.

Research output: Contribution to journalArticle

6 Citations (Scopus)

The biomarker enriched proteome of autosomal dominant polycystic kidney disease cyst fluid

Mason, S. B., Lai, X., Bacallao, R., Biazer-Yost, B. L., Gattone, V. H., Wang, K. C. & Witzmann, F., 2009, In : Proteomics - Clinical Applications. 3, 10, p. 1247-1250 4 p.

Research output: Contribution to journalArticle

Cyst Fluid
Autosomal Dominant Polycystic Kidney
Biomarkers
Proteome
Fluids
206 Citations (Scopus)

The calcimimetic AMG 073 reduces parathyroid hormone and calcium x phosphorus in secondary hyperparathyroidism

Lindberg, J. S., Moe, S., Goodman, W. G., Coburn, J. W., Sprague, S. M., Liu, W., Blaisdell, P. W., Brenner, R. M., Turner, S. A. & Martin, K. J., 2003, In : Kidney International. 63, 1, p. 248-254 7 p.

Research output: Contribution to journalArticle

Secondary Hyperparathyroidism
Parathyroid Hormone
Phosphorus
Calcium
Placebos
70 Citations (Scopus)

The Canagliflozin and Renal Endpoints in Diabetes with Established Nephropathy Clinical Evaluation (CREDENCE) Study Rationale, Design, and Baseline Characteristics

Jardine, M. J., Mahaffey, K. W., Neal, B., Agarwal, R., Bakris, G. L., Brenner, B. M., Bull, S., Cannon, C. P., Charytan, D. M., de Zeeuw, D., Edwards, R., Greene, T., Heerspink, H. J. L., Levin, A., Pollock, C., Wheeler, D. C., Xie, J., Zhang, H., Zinman, B., Desai, M. & 1 others, Perkovic, V., Dec 13 2017, (Accepted/In press) In : American Journal of Nephrology. p. 462-472 11 p.

Research output: Contribution to journalArticle

Kidney Diseases
Kidney
Type 2 Diabetes Mellitus
Glucose
Sodium-Glucose Transporter 2