Publications 1986 2020

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2019

Admission plasma uromodulin and the risk of acute kidney injury in hospitalized patients with cirrhosis: a pilot study

Patidar, K. R., Garimella, P. S., Macedo, E., Slaven, J. E., Ghabril, M. S., Weber, R. E., Anderson, M., Orman, E. S., Nephew, L. D., Desai, A. P., Chalasani, N. P. & El-Achkar, T. M., Oct 1 2019, In : American journal of physiology. Gastrointestinal and liver physiology. 317, 4, p. G447-G452

Research output: Contribution to journalArticle

Uromodulin
Acute Kidney Injury
Fibrosis
Creatinine
Urine

Adrenocorticotropic Hormone in the Treatment of Focal Segmental Glomerulosclerosis Following Kidney Transplantation

Grafals, M. & Sharfuddin, A., Jul 1 2019, In : Transplantation proceedings. 51, 6, p. 1831-1837 7 p.

Research output: Contribution to journalArticle

Open Access
Focal Segmental Glomerulosclerosis
Kidney Transplantation
Adrenocorticotropic Hormone
Gels
Transplants
1 Citation (Scopus)

Analytical validity of a genotyping assay for use with personalized antihypertensive and chronic kidney disease therapy

Collins, K. S., Pratt, V. M., Stansberry, W. M., Medeiros, E. B., Kannegolla, K., Swart, M., Skaar, T., Chapman, A. B., Decker, B., Moorthi, R. & Eadon, M., Jan 1 2019, In : Pharmacogenetics and Genomics. 29, 1, p. 18-22 5 p.

Research output: Contribution to journalArticle

Chronic Renal Insufficiency
Antihypertensive Agents
Hypertension
Disease Progression
Kidney Diseases
Angiotensin Receptor Antagonists
Angiotensin-Converting Enzyme Inhibitors
Chronic Kidney Failure
Longitudinal Studies
Cohort Studies

Angiotensin-related genetic determinants of cardiovascular disease in patients undergoing hemodialysis

Moe, S. M., Long, J., Schwantes-An, T. H. L., Decker, B. S., Wetherill, L., Edenberg, H. J., Xuei, X., Vatta, M., Foroud, T. M. & Chertow, G. M., Nov 1 2019, In : Nephrology Dialysis Transplantation. 34, 11, p. 1924-1931 8 p.

Research output: Contribution to journalArticle

Open Access
Angiotensins
Peptidyl-Dipeptidase A
Renal Dialysis
Cardiovascular Diseases
Single Nucleotide Polymorphism

A novel fluorescent clinical method to rapidly quantify plasma volume

Molitoris, B. A., George, A. G., Murray, P. T., Meier, D., Reilly, E. S., Barreto, E., Sandoval, R. M., Rizk, D. V., Shaw, A. D. & Peacock, W. F., Mar 1 2019, In : CardioRenal Medicine. 9, 3, p. 168-179 12 p.

Research output: Contribution to journalArticle

Open Access
Plasma Volume
Healthy Volunteers
Blood Volume
Dextrans
Fluorescent Dyes

A simple automated method for continuous fieldwise measurement of microvascular hemodynamics

Clendenon, S. G., Fu, X., Von Hoene, R. A., Clendenon, J. L., Sluka, J. P., Winfree, S., Mang, H., Martinez, M., Filson, A. J., Klaunig, J. E., Glazier, J. A. & Dunn, K., May 1 2019, In : Microvascular Research. 123, p. 7-13 7 p.

Research output: Contribution to journalArticle

Spatio-Temporal Analysis
Hemodynamics
Motion Pictures
Blood Vessels
Spreadsheets

Assessment and management of hypertension among patients on peritoneal dialysis

Vaios, V., Georgianos, P. I., Liakopoulos, V. & Agarwal, R., Feb 7 2019, In : Clinical Journal of the American Society of Nephrology. 14, 2, p. 297-305 9 p.

Research output: Contribution to journalArticle

Peritoneal Dialysis
Hypertension
Renal Dialysis
Dietary Sodium
Renal Replacement Therapy

Automatic segmentation of intravital fluorescence microscopy images by K-means clustering of FLIM phasors

Zhang, Y., Hato, T., Dagher, P., Nichols, E. L., Smith, C. J., Dunn, K. & Howard, S. S., Aug 15 2019, In : Optics Letters. 44, 16, p. 3928-3931 4 p.

Research output: Contribution to journalArticle

microscopy
life (durability)
fluorescence
marking
machine learning
1 Citation (Scopus)

A Versatile, Portable Intravital Microscopy Platform for Studying Beta-cell Biology In Vivo

Reissaus, C. A., Piñeros, A. R., Twigg, A. N., Orr, K. S., Conteh, A. M., Martinez, M. M., Kamocka, M., Day, R., Tersey, S. A., Mirmira, R., Dunn, K. & Linnemann, A., Dec 1 2019, In : Scientific Reports. 9, 1, 8449.

Research output: Contribution to journalArticle

Open Access
Biosensing Techniques
Cell Biology
Cell Physiological Phenomena
Aptitude
Calcium Signaling
5 Citations (Scopus)

Bacterial sepsis triggers an antiviral response that causes translation shutdown

Hato, T., Maier, B., Syed, F., Myslinski, J., Zollman, A., Plotkin, Z., Eadon, M. & Dagher, P., Jan 2 2019, In : Journal of Clinical Investigation. 129, 1, CI123284.

Research output: Contribution to journalArticle

Antiviral Agents
Sepsis
Eukaryotic Initiation Factor-2
Eukaryotic Initiation Factors
Kidney
225 Citations (Scopus)

Canagliflozin and renal outcomes in type 2 diabetes and nephropathy

for the CREDENCE Trial Investigators, Jun 13 2019, In : New England Journal of Medicine. 380, 24, p. 2295-2306 12 p.

Research output: Contribution to journalArticle

Type 2 Diabetes Mellitus
Kidney
Confidence Intervals
Chronic Kidney Failure
Placebos
3 Citations (Scopus)

Cardiovascular disease in the kidney transplant recipient: epidemiology, diagnosis and management strategies

Rangaswami, J., Mathew, R. O., Parasuraman, R., Tantisattamo, E., Lubetzky, M., Rao, S., Yaqub, M., Birdwell, K. A., Bennett, W., Dalal, P., Kapoor, R., Lerma, E. V., Lerman, M., McCormick, N., Bangalore, S., McCullough, P. A. & Dadhania, D. M., May 1 2019, In : Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association. 34, 5, p. 760-773 14 p.

Research output: Contribution to journalArticle

Open Access
Kidney Transplantation
Epidemiology
Cardiovascular Diseases
Kidney
Chronic Kidney Failure
8 Citations (Scopus)

Cardiovascular outcome trials in patients with chronic kidney disease: Challenges associated with selection of patients and endpoints

Rossignol, P., Agarwal, R., Canaud, B., Charney, A., Chatellier, G., Craig, J. C., Cushman, W. C., Gansevoort, R. T., Fellström, B., Garza, D., Guzman, N., Holtkamp, F. A., London, G. M., Massy, Z. A., Mebazaa, A., Mol, P. G. M., Pfeffer, M. A., Rosenberg, Y., Ruilope, L. M., Seltzer, J. & 15 others, Shah, A. M., Shah, S., Singh, B., Stefánsson, B. V., Stockbridge, N., Stough, W. G., Thygesen, K., Walsh, M., Wanner, C., Warnock, D. G., Wilcox, C. S., Wittes, J., Pitt, B., Thompson, A. & Zannad, F., Mar 14 2019, In : European Heart Journal. 40, 11, p. 880-886 7 p.

Research output: Contribution to journalArticle

Chronic Renal Insufficiency
Patient Selection
Cardiovascular Diseases
Kidney
Chronic Kidney Failure

Characterizing Dysgeusia in Hemodialysis Patients

Fitzgerald, C., Wiese, G., Moorthi, R., Moe, S., Hill Gallant, K. & Running, C. A., Mar 11 2019, In : Chemical Senses. 44, 3, p. 165-171 7 p.

Research output: Contribution to journalArticle

Dysgeusia
Renal Dialysis
Dialysis
Taste Perception
Sodium Glutamate
4 Citations (Scopus)

Chronic kidney disease and peripheral nerve function in the Health, Aging and Body Composition Study

Moorthi, R., Doshi, S., Fried, L. F., Moe, S., Sarnak, M. J., Satterfield, S., Schwartz, A. V., Shlipak, M., Lange-Maia, B. S., Harris, T. B., Newman, A. B. & Strotmeyer, E. S., Apr 1 2019, In : Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association. 34, 4, p. 625-632 8 p.

Research output: Contribution to journalArticle

Body Composition
Chronic Renal Insufficiency
Peripheral Nerves
Health
Odds Ratio
1 Citation (Scopus)

Circulating uromodulin inhibits systemic oxidative stress by inactivating the TRPM2 channel

LaFavers, K. A., Macedo, E., Garimella, P. S., Lima, C., Khan, S., Myslinski, J., McClintick, J., Witzmann, F. A., Winfree, S., Phillips, C. L., Hato, T., Dagher, P. C., Wu, X. R., El-Achkar, T. M. & Micanovic, R., Oct 2 2019, In : Science translational medicine. 11, 512

Research output: Contribution to journalArticle

Uromodulin
Oxidative Stress
Acute Kidney Injury
Protein Deficiency
Reactive Oxygen Species
3 Citations (Scopus)
Open Access
Clinical Pharmacology
Antihypertensive Agents
Hypertension
Sodium Chloride Symporter Inhibitors
Adrenergic Antagonists

Comparison of risk factors for pediatric kidney stone formation: The effects of sex

Schwaderer, A. L., Raina, R., Khare, A., Safadi, F., Moe, S. & Kusumi, K., Jan 1 2019, In : Frontiers in Pediatrics. 7, FEB, 32.

Research output: Contribution to journalArticle

Open Access
Kidney Calculi
Pediatrics
International Classification of Diseases
Pyuria
Flank Pain

DeepSynth: Three-dimensional nuclear segmentation of biological images using neural networks trained with synthetic data

Dunn, K. W., Fu, C., Ho, D. J., Lee, S., Han, S., Salama, P. & Delp, E. J., Dec 1 2019, In : Scientific reports. 9, 1, 18295.

Research output: Contribution to journalArticle

Open Access
Learning
Three-Dimensional Imaging
Workflow
Microscopy
Fluorescence

Development and Validation of a Model to Predict Acute Kidney Injury in Hospitalized Patients With Cirrhosis

Patidar, K. R., Xu, C., Shamseddeen, H., Cheng, Y. W., Ghabril, M. S., Mukthinuthalapati, V. V. P. K., Fricker, Z. P., Akinyeye, S., Nephew, L. D., Desai, A. P., Anderson, M., El-Achkar, T. M., Chalasani, N. P. & Orman, E. S., Sep 1 2019, In : Clinical and translational gastroenterology. 10, 9, p. e00075

Research output: Contribution to journalArticle

Open Access
Acute Kidney Injury
Fibrosis
End Stage Liver Disease
International Normalized Ratio
Leukocyte Count

Drug-gene and drug-drug interactions associated with tramadol and codeine therapy in the INGENIOUS trial

Fulton, C. R., Zang, Y., Desta, Z., Rosenman, M., Holmes, A., Decker, B., Zhang, Y., T Callaghan, J., Pratt, V. M., Levy, K., Gufford, B. T., Dexter, P., Skaar, T. & Eadon, M., Apr 1 2019, In : Pharmacogenomics. 20, 6, p. 397-408 12 p.

Research output: Contribution to journalArticle

Tramadol
Codeine
Drug Interactions
Cytochrome P-450 CYP2D6
Pharmaceutical Preparations
1 Citation (Scopus)

Effect of ovariectomy on the progression of chronic kidney disease-mineral bone disorder (CKD-MBD) in female Cy/+ rats

Vorland, C. J., Lachcik, P. J., Swallow, E. A., Metzger, C. E., Allen, M., Chen, X. N., Moe, S. & Hill Gallant, K. M., May 28 2019, In : Scientific reports. 9, 1, 1 p.

Research output: Contribution to journalArticle

Open Access
Chronic Kidney Disease-Mineral and Bone Disorder
Ovariectomy
Porosity
Kidney Diseases
Phosphorus

Fibroblast Growth Factor 23 Genotype and Cardiovascular Disease in Patients Undergoing Hemodialysis

Schwantes-An, T. H., Liu, S., Stedman, M., Decker, B., Wetherill, L., Edenberg, H., Vatta, M., Foroud, T., Chertow, G. M. & Moe, S., Jan 1 2019, (Accepted/In press) In : American Journal of Nephrology. p. 125-132 8 p.

Research output: Contribution to journalArticle

Renal Dialysis
Cardiovascular Diseases
Genotype
Heart Failure
Mortality
4 Citations (Scopus)

Increased FGF23 protects against detrimental cardio-renal consequences during elevated blood phosphate in CKD

Clinkenbeard, E. L., Noonan, M. L., Thomas, J. C., Ni, P., Hum, J. M., Aref, M., Swallow, E. A., Moe, S., Allen, M. & White, K., Feb 21 2019, In : JCI insight. 4, 4

Research output: Contribution to journalArticle

Chronic Renal Insufficiency
Phosphates
Adenine
Kidney
Caseins

Increasing Nephrologist Awareness of Symptom Burden in Older Hospitalized End-Stage Renal Disease Patients

Jawed, A., Moe, S. M., Moorthi, R. N., Torke, A. M. & Eadon, M. T., Jan 1 2019, (Accepted/In press) In : American Journal of Nephrology.

Research output: Contribution to journalArticle

Chronic Kidney Failure
Symptom Assessment
Physicians
Pruritus
Palliative Care
3 Citations (Scopus)

KDOQI US Commentary on the 2017 ACC/AHA Hypertension Guideline

Kramer, H. J., Townsend, R. R., Griffin, K., Flynn, J. T., Weiner, D. E., Rocco, M. V., Choi, M. J., Weir, M. R., Chang, T. I., Agarwal, R. & Beddhu, S., Apr 1 2019, In : American Journal of Kidney Diseases. 73, 4, p. 437-458 22 p.

Research output: Contribution to journalArticle

American Heart Association
Kidney Diseases
Cardiology
Guidelines
Hypertension

Kidney Disease Progression Does Not Decrease Intestinal Phosphorus Absorption in a Rat Model of Chronic Kidney Disease–Mineral Bone Disorder

Vorland, C. J., Biruete, A., Lachcik, P. J., Srinivasan, S., Chen, N. X., Moe, S. M. & Hill Gallant, K. M., Jan 1 2019, (Accepted/In press) In : Journal of Bone and Mineral Research.

Research output: Contribution to journalArticle

Intestinal Absorption
Kidney Diseases
Phosphorus
Disease Progression
Kidney
Panniculitis
Allografts
Pancreas
Transplants
Kidney
1 Citation (Scopus)
Chronic Renal Insufficiency
Blood Vessels
Perfusion
Parathyroid Hormone
Therapeutics
3 Citations (Scopus)

Patiromer versus placebo to enable spironolactone use in patients with resistant hypertension and chronic kidney disease (AMBER): a phase 2, randomised, double-blind, placebo-controlled trial

Agarwal, R., Rossignol, P., Romero, A., Garza, D., Mayo, M. R., Warren, S., Ma, J., White, W. B. & Williams, B., Oct 26 2019, In : The Lancet. 394, 10208, p. 1540-1550 11 p.

Research output: Contribution to journalArticle

Spironolactone
Chronic Renal Insufficiency
Placebos
Hypertension
Hyperkalemia

Prediction of Nephropathy in Type 2 Diabetes: An Analysis of the ACCORD Trial Applying Machine Learning Techniques

Rodriguez-Romero, V., Bergstrom, R. F., Decker, B., Lahu, G., Vakilynejad, M. & Bies, R., Jan 1 2019, In : Clinical and translational science.

Research output: Contribution to journalArticle

Open Access
Diabetic Nephropathies
Medical problems
Glomerular Filtration Rate
Type 2 Diabetes Mellitus
Learning systems

Quantitative Kinetic Models from Intravital Microscopy: A Case Study Using Hepatic Transport

Tavakoli, M., Tsekouras, K., Day, R., Dunn, K. W. & Pressé, S., Jan 1 2019, (Accepted/In press) In : Journal of Physical Chemistry B.

Research output: Contribution to journalArticle

liver
Liver
microscopy
drugs
compartments

RegSNPs-intron: A computational framework for predicting pathogenic impact of intronic single nucleotide variants

Lin, H., Hargreaves, K. A., Li, R., Reiter, J. L., Wang, Y., Mort, M., Cooper, D. N., Zhou, Y., Zhang, C., Eadon, M. T., Dolan, M. E., Ipe, J., Skaar, T. C. & Liu, Y., Nov 28 2019, In : Genome Biology. 20, 1, 254.

Research output: Contribution to journalArticle

Open Access
Introns
introns
Nucleotides
nucleotides
assay

Skeletal levels of bisphosphonate in the setting of chronic kidney disease are independent of remodeling rate and lower with fractionated dosing

Swallow, E. A., Aref, M. W., Metzger, C. E., Sacks, S., Lehmkuhler, D. R., Chen, X. N., Hammond, M. A., Territo, P., Nickolas, T. L., Moe, S. & Allen, M., Oct 1 2019, In : Bone. 127, p. 419-426 8 p.

Research output: Contribution to journalArticle

zoledronic acid
Diphosphonates
Chronic Renal Insufficiency
Ulna
Bone Remodeling

Spatial Temporal Analysis of Fieldwise Flow in Microvasculature

Clendenon, S. G., Fu, X., Von Hoene, R. A., Clendenon, J. L., Sluka, J. P., Winfree, S., Mang, H., Martinez, M., Filson, A., Klaunig, J. E., Glazier, J. A. & Dunn, K. W., Nov 18 2019, In : Journal of visualized experiments : JoVE. 153

Research output: Contribution to journalArticle

Spatio-Temporal Analysis
Capillary flow
Microvessels
Flow velocity
Blood
4 Citations (Scopus)

Targeting the hepcidin–ferroportin pathway in anaemia of chronic kidney disease

Sheetz, M., Barrington, P., Callies, S., Berg, P. H., McColm, J., Marbury, T., Decker, B., Dyas, G. L., Truhlar, S. M. E., Benschop, R., Leung, D., Berg, J. & Witcher, D. R., Jan 1 2019, In : British Journal of Clinical Pharmacology.

Research output: Contribution to journalArticle

Chronic Renal Insufficiency
Anemia
Hepcidins
Iron
Ferritins

Tester and testing procedure influence clinically determined gait speed

Warden, S. J., Kemp, A. C., Liu, Z. & Moe, S., Oct 1 2019, In : Gait and Posture. 74, p. 83-86 4 p.

Research output: Contribution to journalArticle

Walking Speed
Research Personnel
Morbidity
Mortality
Research
1 Citation (Scopus)

The archaeal Dps nanocage targets kidney proximal tubules via glomerular filtration

Uchida, M., Maier, B., Waghwani, H. K., Selivanovitch, E., Louise Pay, S., Avera, J., Jun Yun, E., Sandoval, R. M., Molitoris, B., Zollman, A., Douglas, T. & Hato, T., Sep 3 2019, In : Journal of Clinical Investigation. 129, 9, p. 3941-3951 11 p.

Research output: Contribution to journalArticle

Open Access
Proximal Kidney Tubule
Glomerular Filtration Barrier
Endocytosis
Proteins
Antioxidants

The Association Between Kidney Disease and Diabetes Remission in Bariatric Surgery Patients With Type 2 Diabetes

Friedman, A., Wang, J., Wahed, A. S., Docherty, N. G., Fennern, E., Pomp, A., Purnell, J. Q., le Roux, C. W. & Wolfe, B., Jan 1 2019, In : American Journal of Kidney Diseases.

Research output: Contribution to journalArticle

Bariatric Surgery
Kidney Diseases
Chronic Renal Insufficiency
Type 2 Diabetes Mellitus
Glomerular Filtration Rate

The case for a bariatric-centered approach to CKD care

Friedman, A., Feb 7 2019, In : Clinical Journal of the American Society of Nephrology. 14, 2, p. 291-293 3 p.

Research output: Contribution to journalArticle

Open Access
Bariatrics
Open Access
Text Messaging
Medication Adherence
Telemedicine
Chronic Renal Insufficiency
Hispanic Americans
2 Citations (Scopus)

Time course of rapid bone loss and cortical porosity formation observed by longitudinal μCT in a rat model of CKD

McNerny, E. M. B., Buening, D. T., Aref, M. W., Chen, X. N., Moe, S. & Allen, M., Aug 1 2019, In : Bone. 125, p. 16-24 9 p.

Research output: Contribution to journalArticle

Porosity
Tibia
Bone and Bones
X-Ray Microtomography
Chronic Renal Insufficiency
1 Citation (Scopus)

Voluntary wheel running has beneficial effects in a rat model of CKD-mineral bone disorder (CKD-MBD)

Avin, K. G., Allen, M. R., Chen, N. X., Srinivasan, S., O'Neill, K. D., Troutman, A. D., Mast, G., Swallow, E. A., Brown, M. B., Wallace, J. M., Zimmers, T. A., Warden, S. J. & Moe, S. M., Jan 1 2019, In : Journal of the American Society of Nephrology. 30, 10, p. 1898-1909 12 p.

Research output: Contribution to journalArticle

Running
Minerals
Bone and Bones
Cystic Kidney Diseases
Biochemistry
2018
13 Citations (Scopus)

18F-NaF and 18F-FDG as molecular probes in the evaluation of atherosclerosis

McKenney-Drake, M. L., Moghbel, M. C., Paydary, K., Alloosh, M., Houshmand, S., Moe, S., Salavati, A., Sturek, J. M., Territo, P., Weaver, C., Werner, T. J., Høilund-Carlsen, P. F., Sturek, M. & Alavi, A., Jul 6 2018, (Accepted/In press) In : European Journal of Nuclear Medicine and Molecular Imaging. p. 1-11 11 p.

Research output: Contribution to journalArticle

Molecular Probes
Fluorodeoxyglucose F18
Positron-Emission Tomography
Atherosclerosis
Vascular Calcification
6 Citations (Scopus)

A novel method for rapid bedside measurement of GFR

Rizk, D. V., Meier, D., Sandoval, R. M., Chacana, T., Reilly, E. S., Seegmiller, J. C., DeNoia, E., Strickland, J. S., Muldoon, J. & Molitoris, B., Jun 1 2018, In : Journal of the American Society of Nephrology. 29, 6, p. 1609-1613 5 p.

Research output: Contribution to journalArticle

Iohexol
Rhodamines
Plasma Volume
Biomarkers
Cystatin C
2 Citations (Scopus)

A prospective study of the influence of the skeleton on calcium mass transfer during hemodialysis

Goldenstein, P. T., Graciolli, F. G., Antunes, G. L., Dominguez, W. V., dos Reis, L. M., Moe, S., Elias, R. M., Jorgetti, V. & Moysés, R. M. A., Jul 1 2018, In : PLoS One. 13, 7, e0198946.

Research output: Contribution to journalArticle

hemodialysis
prospective studies
mass transfer
Skeleton
skeleton
3 Citations (Scopus)

Blocking HIF signaling via novel inhibitors of CA9 and APE1/Ref-1 dramatically affects pancreatic cancer cell survival

Logsdon, D. P., Shah, F., Carta, F., Supuran, C. T., Kamocka, M., Jacobsen, M. H., Sandusky, G., Kelley, M. & Fishel, M., Dec 1 2018, In : Scientific Reports. 8, 1, 13759.

Research output: Contribution to journalArticle

Pancreatic Neoplasms
Cell Survival
Adenocarcinoma
Oxidation-Reduction
Neoplasms
2 Citations (Scopus)

Blood pressure control in conventional hemodialysis

Georgianos, P. I. & Agarwal, R., Jan 1 2018, (Accepted/In press) In : Seminars in Dialysis.

Research output: Contribution to journalArticle

Renal Dialysis
Blood Pressure
Sodium
Renin-Angiotensin System
Antihypertensive Agents
30 Citations (Scopus)

Effect of bariatric surgery on CKD risk

Friedman, A., Wahed, A. S., Wang, J., Courcoulas, A. P., Dakin, G., Hinojosa, M. W., Kimmel, P. L., Mitchell, J. E., Pomp, A., Pories, W. J., Purnell, J. Q., Le Roux, C., Spaniolas, K., Steffen, K. J., Thirlby, R. & Wolfe, B., Apr 1 2018, In : Journal of the American Society of Nephrology. 29, 4, p. 1289-1300 12 p.

Research output: Contribution to journalArticle

Bariatric Surgery
Albuminuria
Kidney Diseases
Chronic Kidney Failure
Weight Loss