Gastroenterology & Hepatology

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2020

A clinical decision support tool may help to optimise vedolizumab therapy in Crohn’s disease

the GETAID OBSERV-IBD, VICTORY Cohorts Collaboration*, Mar 1 2020, In : Alimentary Pharmacology and Therapeutics. 51, 5, p. 553-564 12 p.

Research output: Contribution to journalArticle

Open Access
2 Scopus citations

A Comparative Study of 22G versus 19G Needles for EUS-Guided Biopsies for Parenchymal Liver Disease: Are Thinner Needles Better?

Patel, H. K., Saxena, R., Rush, N., Patel, S. K., Dasari, C. S., Mneimneh, W., Quickery, A., Rahal, M. A., Temnykh, L., DeWitt, J. & Al-Haddad, M., Jan 1 2020, (Accepted/In press) In : Digestive diseases and sciences.

Research output: Contribution to journalArticle

1 Scopus citations

ADH1B∗2 Is Associated With Reduced Severity of Nonalcoholic Fatty Liver Disease in Adults, Independent of Alcohol Consumption

Vilar-Gomez, E., Sookoian, S., Pirola, C. J., Liang, T., Gawrieh, S., Cummings, O., Liu, W. & Chalasani, N. P., Sep 2020, In : Gastroenterology. 159, 3, p. 929-943 15 p.

Research output: Contribution to journalArticle

Open Access

Admission Factor V Predicts Transplant-Free Survival in Acute Liver Failure

Patidar, K. R., Davis, B. C., Slaven, J. E., Ghabril, M. S., Kubal, C. A., Lee, W. M. & Stravitz, R. T., Jan 1 2020, (Accepted/In press) In : Digestive diseases and sciences.

Research output: Contribution to journalArticle

Alcohol Rehabilitation Within 30 Days of Hospital Discharge Is Associated With Reduced Readmission, Relapse, and Death in Patients With Alcoholic Hepatitis

Peeraphatdit, T. B., Kamath, P. S., Karpyak, V. M., Davis, B., Desai, V., Liangpunsakul, S., Sanyal, A., Chalasani, N., Shah, V. H. & Simonetto, D. A., Feb 2020, In : Clinical Gastroenterology and Hepatology. 18, 2, p. 477-485.e5

Research output: Contribution to journalArticle

5 Scopus citations

An Open-Label, Dose-Escalation Study to Assess the Safety and Efficacy of IL-22 Agonist F-652 in Patients With Alcohol-associated Hepatitis

Arab, J. P., Sehrawat, T. S., Simonetto, D. A., Verma, V. K., Feng, D., Tang, T., Dreyer, K., Yan, X., Daley, W. L., Sanyal, A., Chalasani, N., Radaeva, S., Yang, L., Vargas, H., Ibacache, M., Gao, B., Gores, G. J., Malhi, H., Kamath, P. S. & Shah, V. H., Aug 1 2020, In : Hepatology. 72, 2, p. 441-453 13 p.

Research output: Contribution to journalArticle

11 Scopus citations

Apolipoprotein B and PNPLA3 Double Heterozygosity in a Father–Son Pair With Advanced Nonalcoholic Fatty Liver Disease

Jansson-Knodell, C. L., Gawrieh, S., McIntyre, A. D., Liang, T., Hegele, R. A. & Chalasani, N., Jan 1 2020, In : Hepatology. 71, 1, p. 383-385 3 p.

Research output: Contribution to journalArticle

A Quantitative Global Proteomics Approach Identifies Candidate Urinary Biomarkers That Correlate With Intraductal Papillary Mucinous Neoplasm Dysplasia

Flick, K. F., Yip-Schneider, M., Sublette, C. M., Simpson, R. E., Colgate, C. L., Wu, H., Soufi, M., DeWitt, J., Mosley, A. L., Ceppa, E. P., Zhang, J. & Schmidt, C. M., Sep 1 2020, In : Pancreas. 49, 8, p. 1044-1051 8 p.

Research output: Contribution to journalArticle

A randomized, placebo-controlled, phase II study of obeticholic acid for primary sclerosing cholangitis

AESOP Study Investigators, Jul 2020, In : Journal of Hepatology. 73, 1, p. 94-101 8 p.

Research output: Contribution to journalArticle

Open Access
5 Scopus citations
Open Access

Ashwagandha-induced liver injury: A case series from Iceland and the US Drug-Induced Liver Injury Network

Björnsson, H. K., Björnsson, E. S., Avula, B., Khan, I. A., Jonasson, J. G., Ghabril, M., Hayashi, P. H. & Navarro, V., Apr 1 2020, In : Liver International. 40, 4, p. 825-829 5 p.

Research output: Contribution to journalArticle

2 Scopus citations

Associations between Mean Arterial Pressure and Poor ICU Outcomes in Critically Ill Patients with Cirrhosis: Is 65 the Sweet Spot?

Patidar, K. R., Peng, J. L., Pike, F., Orman, E. S., Glick, M., Kettler, C. D., Nephew, L. D., Desai, A. P., Nair, K., Khan, B. A., Buckley, C. A., Machado, R., Chalasani, N. P. & Ghabril, M. S., Sep 1 2020, In : Critical care medicine. p. 753-760 8 p.

Research output: Contribution to journalArticle

Automated quantification and architectural pattern detection of hepatic fibrosis in NAFLD

Gawrieh, S., Sethunath, D., Cummings, O. W., Kleiner, D. E., Vuppalanchi, R., Chalasani, N. & Tuceryan, M., Aug 2020, In : Annals of Diagnostic Pathology. 47, 151518.

Research output: Contribution to journalArticle

Blockade of IL-17 signaling reverses alcohol-induced liver injury and excessive alcohol drinking in mice

Xu, J., Ma, H. Y., Liu, X., Rosenthal, S., Baglieri, J., McCubbin, R., Sun, M., Koyama, Y., Geoffroy, C. G., Saijo, K., Shang, L., Nishio, T., Maricic, I., Kreifeldt, M., Kusumanchi, P., Roberts, A., Zheng, B., Kumar, V., Zengler, K., Pizzo, D. P. & 10 others, Hosseini, M., Contet, C., Glass, C. K., Liangpunsakul, S., Tsukamoto, H., Gao, B., Karin, M., Brenner, D. A., Koob, G. F. & Kisseleva, T., Feb 13 2020, In : JCI Insight. 5, 3, e131277.

Research output: Contribution to journalArticle

Open Access
2 Scopus citations

Cannabidiol (CBD) Consumption and Perceived Impact on Extrahepatic Symptoms in Patients with Autoimmune Hepatitis

Mathur, K., Vuppalanchi, V., Gelow, K., Vuppalanchi, R. & Lammert, C., Jan 1 2020, In : Digestive diseases and sciences. 65, 1, p. 322-328 7 p.

Research output: Contribution to journalArticle

Open Access

Changing epidemiology and outcomes of acute kidney injury in hospitalized patients with cirrhosis – a US population-based study

Desai, A. P., Knapp, S. M., Orman, E., Ghabril, M., Nephew, L. D., Anderson, M., Ginès, P., Chalasani, N. P. & Patidar, K. R., 2020, (Accepted/In press) In : Journal of Hepatology.

Research output: Contribution to journalArticle

Chronic-plus-binge alcohol intake induces production of proinflammatory mtDNA-enriched extracellular vesicles and steatohepatitis via ASK1/ p38MAPKα-dependent mechanisms

Ma, J., Cao, H., Rodrigues, R. M., Xu, M., Ren, T., He, Y., Hwang, S., Feng, D., Ren, R., Yang, P., Liangpunsakul, S., Sun, J. & Gao, B., Jun 23 2020, In : JCI Insight. 5, 14, e136496.

Research output: Contribution to journalArticle

Open Access

Clinical Characteristics and Adverse Impact of Hepatotoxicity due to Immune Checkpoint Inhibitors

Miller, E. D., Abu-Sbeih, H., Styskel, B., Nogueras Gonzalez, G. M., Blechacz, B., Naing, A. & Chalasani, N., Feb 1 2020, In : The American journal of gastroenterology. 115, 2, p. 251-261 11 p.

Research output: Contribution to journalArticle

4 Scopus citations

Colorectal polyp prevalence and aspirational detection targets determined using high definition colonoscopy and a high level detector in 2017

Rex, D. K., Sullivan, A. W., Perkins, A. J. & Vemulapalli, K. C., Jan 2020, In : Digestive and Liver Disease. 52, 1, p. 72-78 7 p.

Research output: Contribution to journalArticle

1 Scopus citations

Comparative safety and effectiveness of vedolizumab to tumour necrosis factor antagonist therapy for Crohn's disease

Bohm, M., Xu, R., Zhang, Y., Varma, S., Fischer, M., Kochhar, G., Boland, B., Singh, S., Hirten, R., Ungaro, R., Shmidt, E., Lasch, K., Jairaith, V., Hudesman, D., Chang, S., Lukin, D., Swaminath, A., Sands, B. E., Colombel, J. F., Kane, S. & 16 others, Loftus, E. V., Shen, B., Siegel, C. A., Sandborn, W. J., Dulai, P. S., Kadire, S., Tran, G., Rahal, M., Aniwan, S., Meserve, J., Weiss, A., Koliani-Pace, J. L., Campbell, J. P., Faleck, D., Winters, A. & Chablaney, S., 2020, (Accepted/In press) In : Alimentary Pharmacology and Therapeutics.

Research output: Contribution to journalArticle

Open Access
1 Scopus citations

Constant-severe pain in chronic pancreatitis is associated with genetic loci for major depression in the NAPS2 cohort

For the NAPS2 study group, Oct 1 2020, In : Journal of Gastroenterology. 55, 10, p. 1000-1009 10 p.

Research output: Contribution to journalArticle

Correction to: Characterization of Proximal Small Intestinal Microbiota in Patients With Suspected Small Intestinal Bacterial Overgrowth: A Cross-Sectional Study

Shin, A. S., Gao, X., Bohm, M., Lin, H., Gupta, A., Nelson, D. E., Toh, E., Teagarden, S., Siwiec, R., Dong, Q. & Wo, J. M., Feb 1 2020, In : Clinical and translational gastroenterology. 11, 2, p. e00142

Research output: Contribution to journalArticle

Open Access

Diagnosis and Treatment of Alcohol-Associated Liver Diseases: 2019 Practice Guidance From the American Association for the Study of Liver Diseases

Crabb, D. W., Im, G. Y., Szabo, G., Mellinger, J. L. & Lucey, M. R., Jan 1 2020, In : Hepatology. 71, 1, p. 306-333 28 p.

Research output: Contribution to journalArticle

Open Access
33 Scopus citations

Discovery of 318 new risk loci for type 2 diabetes and related vascular outcomes among 1.4 million participants in a multi-ancestry meta-analysis

The HPAP Consortium, Regeneron Genetics Center & VA Million Veteran Program, Jul 1 2020, In : Nature genetics. 52, 7, p. 680-691 12 p.

Research output: Contribution to journalArticle

1 Scopus citations

Distinctive Features and Outcomes of Hepatocellular Carcinoma in Patients With Alcohol-Related Liver Disease: A US Multicenter Study

deLemos, A., Patel, M., Gawrieh, S., Burney, H., Dakhoul, L., Miller, E., Scanga, A., Kettler, C., Liu, H., Roche, P., Wattacheril, J. & Chalasani, N., Mar 1 2020, In : Clinical and translational gastroenterology. 11, 3, p. e00139

Research output: Contribution to journalArticle

Open Access

Effects of Belapectin, an Inhibitor of Galectin-3, in Patients With Nonalcoholic Steatohepatitis With Cirrhosis and Portal Hypertension

The Belapectin (GR-MD-02) Study Investigators, Apr 2020, In : Gastroenterology. 158, 5, p. 1334-1345.e5

Research output: Contribution to journalArticle

Open Access
13 Scopus citations

Endocuff Vision Reduces Inspection Time Without Decreasing Lesion Detection: A Clinical Randomized Trial

Rex, D. K., Slaven, J. E., Garcia, J., Lahr, R., Searight, M. & Gross, S. A., Jan 2020, In : Clinical Gastroenterology and Hepatology. 18, 1, p. 158-162.e1

Research output: Contribution to journalArticle

7 Scopus citations

Endoscopy Staff Are Concerned About Acquiring Coronavirus Disease 2019 Infection When Resuming Elective Endoscopy

Rex, D. K., Vemulapalli, K. C., Lahr, R. E., McHenry, L., Sherman, S. & Al-Haddad, M., Sep 2020, In : Gastroenterology. 159, 3, p. 1167-1169.e3

Research output: Contribution to journalArticle

Open Access

EUS-guided confocal laser endomicroscopy: prediction of dysplasia in intraductal papillary mucinous neoplasms (with video)

Krishna, S. G., Hart, P. A., DeWitt, J. M., DiMaio, C. J., Kongkam, P., Napoleon, B., Othman, M. O., Yew Tan, D. M., Strobel, S. G., Stanich, P. P., Patel, A., Luthra, A. K., Chan, M. Q., Blaszczak, A. M., Lee, D., El-Dika, S., McCarthy, S. T., Walker, J. P., Arnold, C. A., Porter, K. & 1 others, Conwell, D. L., Mar 2020, In : Gastrointestinal endoscopy. 91, 3, p. 551-563.e5

Research output: Contribution to journalArticle

2 Scopus citations

Extra-hepatic comorbidity burden significantly increases 90-day mortality in patients with cirrhosis and high model for endstage liver disease

Coppel, S., Mathur, K., Ekser, B., Patidar, K. R., Orman, E., Desai, A. P., Vilar-Gomez, E., Kubal, C., Chalasani, N., Nephew, L. & Ghabril, M., Sep 16 2020, In : BMC Gastroenterology. 20, 1, 302.

Research output: Contribution to journalArticle

Open Access

Features of Blood Clotting on Thromboelastography in Hospitalized Patients With Cirrhosis

Shamseddeen, H., Patidar, K. R., Ghabril, M., Desai, A. P., Nephew, L., Kuehl, S., Chalasani, N. & Orman, E. S., 2020, (Accepted/In press) In : American Journal of Medicine.

Research output: Contribution to journalArticle

Fecal Microbiome Distinguishes Alcohol Consumption From Alcoholic Hepatitis But Does Not Discriminate Disease Severity

Smirnova, E., Puri, P., Muthiah, M. D., Daitya, K., Brown, R., Chalasani, N., Liangpunsakul, S., Shah, V. H., Gelow, K., Siddiqui, M. S., Boyett, S., Mirshahi, F., Sikaroodi, M., Gillevet, P. & Sanyal, A. J., Jul 1 2020, In : Hepatology. 72, 1, p. 271-286 16 p.

Research output: Contribution to journalArticle

5 Scopus citations

Fecal Microbiota Transplantation: Redefining Surgical Management of Refractory Clostridium difficile Infection

Cheng, Y. W. & Fischer, M., Mar 1 2020, In : Clinics in Colon and Rectal Surgery. 33, 2, p. 92-97 6 p.

Research output: Contribution to journalArticle

Fecal Microbiota Transplant Decreases Mortality in Patients with Refractory Severe or Fulminant Clostridioides difficile Infection

Cheng, Y. W., Phelps, E., Nemes, S., Rogers, N., Sagi, S., Bohm, M., El-Halabi, M., Allegretti, J. R., Kassam, Z., Xu, H. & Fischer, M., Sep 2020, In : Clinical Gastroenterology and Hepatology. 18, 10, p. 2234-2243.e1

Research output: Contribution to journalArticle

3 Scopus citations

Gender Matters: Characteristics of Hepatocellular Carcinoma in Women From a Large, Multicenter Study in the United States

Phipps, M., Livanos, A., Guo, A., Pomenti, S., Yeh, J., Dakhoul, L., Burney, H., Kettler, C., Liu, H., Miller, E., Gawrieh, S., deLemos, A., Scanga, A., Chalasani, N. & Wattacheril, J., Sep 1 2020, In : The American journal of gastroenterology. 115, 9, p. 1486-1495 10 p.

Research output: Contribution to journalArticle

Hospital-Acquired Versus Community-Acquired Acute Kidney Injury in Patients With Cirrhosis: A Prospective Study

Patidar, K. R., Shamseddeen, H., Xu, C., Ghabril, M., Nephew, L. D., Desai, A. P., Anderson, M., Ashkar (El-Achkar), T., Ginès, P., Chalasani, N. P. & Orman, E., Sep 1 2020, In : The American journal of gastroenterology. 115, 9, p. 1505-1512 8 p.

Research output: Contribution to journalArticle

Impact of a ring-fitted cap on insertion time and adenoma detection: a randomized controlled trial

Rex, D. K., Kessler, W. R., Sagi, S. V., Rogers, N. A., Fischer, M., Bohm, M. E., Wo, J. M., Dewitt, J. M., McHenry, L., Lahr, R. E., Searight, M. P., MacPhail, M., Sullivan, A. W., McWhinney, C. D. & Vemulapalli, K. C., Jan 2020, In : Gastrointestinal endoscopy. 91, 1, p. 115-120 6 p.

Research output: Contribution to journalArticle

2 Scopus citations

Impact of Recipient Age in Combined Liver-Kidney Transplantation: Caution Is Needed for Patients ≥70 Years

Ekser, B., Goggins, W. C., Fridell, J. A., Mihaylov, P., Mangus, R. S., Lutz, A. J., Soma, D., Ghabril, M. S., Lacerda, M. A., Powelson, J. A. & Kubal, C. A., 2020, (Accepted/In press) In : Transplantation Direct. e563.

Research output: Contribution to journalArticle

Open Access

Incidence and risk factors of recurrent clostridioides difficile infection in patients with cirrhosis

Phatharacharukul, P., Purpura, R. D., Gandhi, D., Xu, H., Bickett-Burkhart, K., Chalasani, N., Fischer, M. & Orman, E. S., 2020, In : Clinical and translational gastroenterology. 11, 7, e00189.

Research output: Contribution to journalArticle

Open Access

In search of stool donors: a multicenter study of prior knowledge, perceptions, motivators, and deterrents among potential donors for fecal microbiota transplantation

McSweeney, B., Allegretti, J. R., Fischer, M., Xu, H., Goodman, K. J., Monaghan, T., McLeod, C., Mullish, B. H., Petrof, E. O., Phelps, E. L., Chis, R., Edmison, A., Juby, A., Ennis-Davis, R., Roach, B., Wong, K. & Kao, D., Jan 2 2020, In : Gut Microbes. 11, 1, p. 51-62 12 p.

Research output: Contribution to journalArticle

Open Access
3 Scopus citations

Liver Injury in Patients With Cholestatic Liver Disease Treated With Obeticholic Acid

Eaton, J. E., Vuppalanchi, R., Reddy, R., Sathapathy, S., Ali, B. & Kamath, P. S., Apr 1 2020, In : Hepatology. 71, 4, p. 1511-1514 4 p.

Research output: Contribution to journalArticle

3 Scopus citations

Long-Term Assessment of the Cecal Intubation Rates in High-Performing Colonoscopists: Time for Review

Vemulapalli, K. C., Wilder, S. W., Kahi, C. J. & Rex, D., Mar 1 2020, In : Clinical and translational gastroenterology. 11, 3, p. e00153

Research output: Contribution to journalArticle

Open Access

Long-Term Efficacy and Safety of Fecal Microbiota Transplantation for Treatment of Recurrent Clostridioides difficile Infection

Perler, B. K., Chen, B., Phelps, E., Allegretti, J. R., Fischer, M., Ganapini, V., Krajiceck, E., Kumar, V., Marcus, J., Nativ, L. & Kelly, C. R., Sep 1 2020, In : Journal of Clinical Gastroenterology. 54, 8, p. 701-706 6 p.

Research output: Contribution to journalArticle

3 Scopus citations

Low Incidence of Aerodigestive Cancers in Patients With Negative Results From Colonoscopies, Regardless of Findings From Multitarget Stool DNA Tests

Berger, B. M., Kisiel, J. B., Imperiale, T. F., Geenen, D. J., Heigh, R. I., Mahoney, D. W. & Hilsden, R. J., Apr 2020, In : Clinical Gastroenterology and Hepatology. 18, 4, p. 864-871 8 p.

Research output: Contribution to journalArticle

Open Access
3 Scopus citations

Modulation of the Tryptophan Hydroxylase 1/Monoamine Oxidase-A/5-Hydroxytryptamine/5-Hydroxytryptamine Receptor 2A/2B/2C Axis Regulates Biliary Proliferation and Liver Fibrosis During Cholestasis

Kyritsi, K., Chen, L., O’Brien, A., Francis, H., Hein, T. W., Venter, J., Wu, N., Ceci, L., Zhou, T., Zawieja, D., Gashev, A. A., Meng, F., Invernizzi, P., Fabris, L., Wu, C., Skill, N. J., Saxena, R., Liangpunsakul, S., Alpini, G. & Glaser, S. S., Mar 1 2020, In : Hepatology. 71, 3, p. 990-1008 19 p.

Research output: Contribution to journalArticle

2 Scopus citations

Most Patients Are Willing to Undergo Elective Endoscopic Procedures During the Reopening Period of the Coronavirus 2019 Pandemic

Rex, D. K., Vemulapalli, K. C., Kane, M. J., McHenry, L., Sherman, S. & Al-Haddad, M., Sep 2020, In : Gastroenterology. 159, 3, p. 1173-1175.e4

Research output: Contribution to journalArticle

Open Access
Open Access
1 Scopus citations