A. Dunker

  • 31420 Citations
  • 84 h-Index
1969 …2020

Research output per year

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Publications

2K09 and thereafter: The coming era of integrative bioinformatics, systems biology and intelligent computing for functional genomics and personalized medicine research

Yang, J. Y., Niemierko, A., Bajcsy, R., Xu, D., Athey, B. D., Zhang, A., Ersoy, O. K., Li, G. Z., Borodovsky, M., Zhang, J. C., Arabnia, H. R., Deng, Y., Dunker, A. K., Liu, Y. & Ghafoor, A., Nov 29 2010, In : BMC genomics. 11, SUPPL. 3, I1.

Research output: Contribution to journalArticle

5 Scopus citations

Aberrant mobility phenomena of the DNA repair protein XPA

Iakoucheva, L. M., Kimzey, A. L., Masselon, C. D., Smith, R. D., Dunker, A. K. & Ackerman, E. J., Jul 4 2001, In : Protein Science. 10, 7, p. 1353-1362 10 p.

Research output: Contribution to journalArticle

96 Scopus citations

Abundance and functional roles of intrinsic disorder in allergenic proteins and allergen representative peptides

Xue, B., Soeria-Atmadja, D., Gustafsson, M. G., Hammerling, U., Dunker, A. K. & Uversky, V. N., Sep 1 2011, In : Proteins: Structure, Function and Bioinformatics. 79, 9, p. 2595-2606 12 p.

Research output: Contribution to journalArticle

5 Scopus citations

Abundance of intrinsic disorder in protein associated with cardiovascular disease

Cheng, Y., LeGall, T., Oldfield, C. J., Dunker, A. K. & Uversky, V. N., Sep 5 2006, In : Biochemistry. 45, 35, p. 10448-10460 13 p.

Research output: Contribution to journalArticle

131 Scopus citations

A comparative analysis of viral matrix proteins using disorder predictors

Goh, G. K. M., Dunker, A. K. & Uversky, V. N., Nov 10 2008, In : Virology Journal. 5, 126.

Research output: Contribution to journalArticle

41 Scopus citations

A computational investigation of allostery in the catabolite activator protein

Li, W., Uversky, V. N., Dunker, A. K. & Meroueh, S. O., Dec 19 2007, In : Journal of the American Chemical Society. 129, 50, p. 15668-15676 9 p.

Research output: Contribution to journalArticle

60 Scopus citations

A creature with a hundred waggly tails: Intrinsically disordered proteins in the ribosome

Peng, Z., Oldfield, C. J., Xue, B., Mizianty, M. J., Dunker, A. K., Kurgan, L. & Uversky, V. N., Apr 2014, In : Cellular and Molecular Life Sciences. 71, 8, p. 1477-1504 28 p.

Research output: Contribution to journalArticle

64 Scopus citations

Addressing the intrinsic disorder bottleneck in structural proteomics

Oldfield, C. J., Ulrich, E. L., Cheng, Y., Dunker, A. K. & Markley, J. L., May 15 2005, In : Proteins: Structure, Function and Genetics. 59, 3, p. 444-453 10 p.

Research output: Contribution to journalArticle

69 Scopus citations

Advances in translational bioinformatics facilitate revealing the landscape of complex disease mechanisms

Yang, J. Y., Dunker, A. K., Liu, J. S., Qin, X., Arabnia, H. R., Yang, W., Niemierko, A., Chen, Z., Luo, Z., Wang, L., Liu, Y., Xu, D., Deng, Y., Tong, W. & Yang, M. Q., Dec 16 2014, In : BMC bioinformatics. 15, 17, I1.

Research output: Contribution to journalEditorial

8 Scopus citations

A functionally required unfoldome from the plant kingdom: Intrinsically disordered N-terminal domains of GRAS proteins are involved in molecular recognition during plant development

Sun, X., Xue, B., Jones, W. T., Rikkerink, E., Dunker, A. K. & Uversky, V. N., Oct 1 2011, In : Plant Molecular Biology. 77, 3, p. 205-223 19 p.

Research output: Contribution to journalArticle

78 Scopus citations

Alternative splicing in concert with protein intrinsic disorder enables increased functional diversity in multicellular organisms

Romero, P. R., Zaidi, S., Fang, Y. Y., Uversky, V. N., Radivojac, P., Oldfield, C. J., Cortese, M. S., Sickmeier, M., LeGall, T., Obradovic, Z. & Dunker, A. K., May 30 2006, In : Proceedings of the National Academy of Sciences of the United States of America. 103, 22, p. 8390-8395 6 p.

Research output: Contribution to journalArticle

294 Scopus citations

Alternative splicing of intrinsically disordered regions and rewiring of protein interactions

Buljan, M., Chalancon, G., Dunker, A. K., Bateman, A., Balaji, S., Fuxreiter, M. & Babu, M. M., Jun 1 2013, In : Current Opinion in Structural Biology. 23, 3, p. 443-450 8 p.

Research output: Contribution to journalReview article

100 Scopus citations

A model for fd phage penetration and assembly

Dunker, A. K., Ensign, L. D., Arnold, G. E. & Roberts, L. M., Nov 4 1991, In : FEBS Letters. 292, 1-2, p. 271-274 4 p.

Research output: Contribution to journalArticle

25 Scopus citations

A model for membrane transport through α-helical protein pores

Keith Dunker, A. & Marvin, D. A., May 8 1978, In : Journal of Theoretical Biology. 72, 1, p. 9-16 8 p.

Research output: Contribution to journalArticle

51 Scopus citations

An alphabet of amino acid conformations in protein

Miller, R. T., Douthart, R. J. & Dunker, A. K., Jan 1 1993, Proceedings of the 26th Hawaii International Conference on System Sciences, HICSS 1993. IEEE Computer Society, p. 689-698 10 p. 270672. (Proceedings of the Annual Hawaii International Conference on System Sciences; vol. 1).

Research output: Chapter in Book/Report/Conference proceedingConference contribution

1 Scopus citations

Analysis of Molecular Recognition Features (MoRFs)

Mohan, A., Oldfield, C. J., Radivojac, P., Vacic, V., Cortese, M. S., Dunker, A. K. & Uversky, V. N., Oct 6 2006, In : Journal of molecular biology. 362, 5, p. 1043-1059 17 p.

Research output: Contribution to journalArticle

483 Scopus citations

Analysis of protein-nucleic acid filter binding using the poisson distribution: A method to estimate co-operativity

Dunker, A. K., Apr 1 1975, In : FEBS Letters. 52, 2, p. 323-326 4 p.

Research output: Contribution to journalArticle

7 Scopus citations

Analysis of structured and intrinsically disordered regions of transmembrane proteins

Xue, B., Li, L., Meroueh, S. O., Uversky, V. N. & Dunker, A. K., Dec 1 2009, In : Molecular BioSystems. 5, 12, p. 1688-1702 15 p.

Research output: Contribution to journalArticle

47 Scopus citations

An assignment of intrinsically disordered regions of proteins based on NMR structures

Ota, M., Koike, R., Amemiya, T., Tenno, T., Romero, P. R., Hiroaki, H., Dunker, A. K. & Fukuchi, S., Jan 1 2013, In : Journal of Structural Biology. 181, 1, p. 29-36 8 p.

Research output: Contribution to journalArticle

15 Scopus citations

A new machine learning approach for protein phosphorylation site prediction in plants

Gao, J., Agrawal, G. K., Thelen, J. J., Obradovic, Z., Dunker, A. K. & Xu, D., Aug 11 2009, Bioinformatics and Computational Biology - First International Conference, BICoB 2009, Proceedings. p. 18-29 12 p. (Lecture Notes in Computer Science (including subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics); vol. 5462 LNBI).

Research output: Chapter in Book/Report/Conference proceedingConference contribution

17 Scopus citations

A new method for determining protein secondary structure by laser raman spectroscopy applied to FD phage

Williams, R. W., Dunker, A. K. & Peticolas, W. L., Jan 1 1980, In : Biophysical journal. 32, 1, p. 232-234 3 p.

Research output: Contribution to journalArticle

18 Scopus citations

Another disordered chameleon: The micro-exon gene 14 protein from schistosomiasis

Dunker, A. K., Jun 4 2013, In : Biophysical journal. 104, 11, p. 2326-2328 3 p.

Research output: Contribution to journalShort survey

2 Scopus citations

Another Window into Disordered Protein Function

Dunker, A. K., Sep 11 2007, In : Structure. 15, 9, p. 1026-1028 3 p.

Research output: Contribution to journalShort survey

14 Scopus citations

A Protein Domain-Based Interactome Network for C. elegans Early Embryogenesis

Boxem, M., Maliga, Z., Klitgord, N., Li, N., Lemmens, I., Mana, M., de Lichtervelde, L., Mul, J. D., van de Peut, D., Devos, M., Simonis, N., Yildirim, M. A., Cokol, M., Kao, H. L., de Smet, A. S., Wang, H., Schlaitz, A. L., Hao, T., Milstein, S., Fan, C. & 17 others, Tipsword, M., Drew, K., Galli, M., Rhrissorrakrai, K., Drechsel, D., Koller, D., Roth, F. P., Iakoucheva, L. M., Dunker, A. K., Bonneau, R., Gunsalus, K. C., Hill, D. E., Piano, F., Tavernier, J., van den Heuvel, S., Hyman, A. A. & Vidal, M., Aug 8 2008, In : Cell. 134, 3, p. 534-545 12 p.

Research output: Contribution to journalArticle

144 Scopus citations
34 Scopus citations

Archaic chaos: Intrinsically disordered proteins in Archaea

Xue, B., Williams, R. W., Oldfield, C. J., Dunker, A. K. & Uversky, V. N., May 28 2010, In : BMC Systems Biology. 4, SUPPL. 1, S1.

Research output: Contribution to journalArticle

82 Scopus citations

Assessing secondary structure assignment of protein structures by using pairwise sequence-alignment benchmarks

Zhang, W., Dunker, A. K. & Zhou, Y., Apr 1 2008, In : Proteins: Structure, Function and Genetics. 71, 1, p. 61-67 7 p.

Research output: Contribution to journalArticle

21 Scopus citations

Atomic force microscopy of DNA and bacteriophage in air, water and propanol: The role of adhesion forces

Lyubchenko, Y. L., Oden, P. I., Lampner, D., Lindsay, S. M. & Dunker, K. A., Mar 11 1993, In : Nucleic acids research. 21, 5, p. 1117-1123 7 p.

Research output: Contribution to journalArticle

149 Scopus citations

Back to the future: Nuclear magnetic resonance and bioinformatics studies on intrinsically disordered proteins

Dunker, A. & Oldfield, C. J., Sep 19 2015, Intrinsically Disordered Proteins Studied by NMR Spectroscopy. Springer International Publishing, p. 1-34 34 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

4 Scopus citations

Back to the future: Nuclear magnetic resonance and bioinformatics studies on intrinsically disordered proteins

Dunker, A. K. & Oldfield, C. J., Sep 22 2015, Advances in Experimental Medicine and Biology. Springer New York LLC, p. 1-34 34 p. (Advances in Experimental Medicine and Biology; vol. 870).

Research output: Chapter in Book/Report/Conference proceedingChapter

7 Scopus citations

Binding promiscuity of unfolded peptides

Oldfield, C. J., Xue, B., Dunker, A. K. & Uversky, V. N., Feb 22 2012, Protein and Peptide Folding, Misfolding, and Non-Folding. John Wiley and Sons, p. 239-277 39 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

Biochemistry: Controlled chaos

Uversky, V. N. & Dunker, A. K., Nov 28 2008, In : Science. 322, 5906, p. 1340-1341 2 p.

Research output: Contribution to journalShort survey

54 Scopus citations

Ca2+-induced folding and aggregation of skeletal muscle sarcoplasmic reticulum calsequestrin. The involvement of the trifluoperazine-binding site

He, Z., Dunker, A. K., Wesson, C. R. & Trumble, W. R., Jan 1 1993, In : Journal of Biological Chemistry. 268, 33, p. 24635-24641 7 p.

Research output: Contribution to journalArticle

55 Scopus citations

Calmodulin signaling: Analysis and prediction of a disorder-dependent molecular recognition

Radivojac, P., Vucetic, S., O'Connor, T. R., Uversky, V. N., Obradovic, Z. & Dunker, A. K., May 1 2006, In : Proteins: Structure, Function and Genetics. 63, 2, p. 398-410 13 p.

Research output: Contribution to journalArticle

84 Scopus citations

CDF it all: Consensus prediction of intrinsically disordered proteins based on various cumulative distribution functions

Xue, B., Oldfield, C. J., Dunker, A. K. & Uversky, V. N., May 6 2009, In : FEBS Letters. 583, 9, p. 1469-1474 6 p.

Research output: Contribution to journalArticle

95 Scopus citations

Changes in predicted protein disorder tendency may contribute to disease risk

Hu, Y., Liu, Y., Jung, J., Dunker, A. K. & Wang, Y., Dec 23 2011, In : BMC genomics. 12, SUPPL. 5, S2.

Research output: Contribution to journalArticle

9 Scopus citations

Characterization of aleutian mink disease virus

Yoon, J. W., Dunker, A. K. & Kenyon, A. J., Apr 1975, In : Virology. 64, 2, p. 575-580 6 p.

Research output: Contribution to journalArticle

3 Scopus citations

Characterization of hepatic carnitine palmitoyltransferase. Use of bromoacyl derivatives and antibodies

Brady, P. S., Dunker, A. K. & Brady, L. J., Jan 1 1987, In : Biochemical Journal. 241, 3, p. 751-757 7 p.

Research output: Contribution to journalArticle

6 Scopus citations

Characterization of molecular recognition features, MoRFs, and their binding partners

Vacic, V., Oldfield, C. J., Mohan, A., Radivojac, P., Cortese, M. S., Uversky, V. N. & Dunker, A. K., Jun 1 2007, In : Journal of Proteome Research. 6, 6, p. 2351-2366 16 p.

Research output: Contribution to journalArticle

319 Scopus citations

Circular dichroism studies of fd coat protein in membrane vesicles

Williams, R. W. & Dunker, A. K., Dec 1 1977, In : Journal of Biological Chemistry. 252, 18, p. 6253-6255 3 p.

Research output: Contribution to journalArticle

34 Scopus citations

Classification and knowledge discovery in protein databases

Radivojac, P., Chawla, N. V., Dunker, A. K. & Obradovic, Z., Aug 1 2004, In : Journal of biomedical informatics. 37, 4, p. 224-239 16 p.

Research output: Contribution to journalArticle

63 Scopus citations

Classification of intrinsically disordered regions and proteins

Van Der Lee, R., Buljan, M., Lang, B., Weatheritt, R. J., Daughdrill, G. W., Dunker, A. K., Fuxreiter, M., Gough, J., Gsponer, J., Jones, D. T., Kim, P. M., Kriwacki, R. W., Oldfield, C. J., Pappu, R. V., Tompa, P., Uversky, V. N., Wright, P. E. & Babu, M. M., Jul 9 2014, In : Chemical Reviews. 114, 13, p. 6589-6631 43 p.

Research output: Contribution to journalReview article

687 Scopus citations

Close encounters of the third kind: Disordered domains and the interactions of proteins

Tompa, P., Fuxreiter, M., Oldfield, C. J., Simon, I., Dunker, A. K. & Uversky, V. N., Apr 27 2009, In : BioEssays. 31, 3, p. 328-335 8 p.

Research output: Contribution to journalArticle

180 Scopus citations

Clusterin, a binding protein with a molten globule-like region

Bailey, R. W., Dunker, A. K., Brown, C. J., Garner, E. C. & Griswold, M. D., Oct 2 2001, In : Biochemistry. 40, 39, p. 11828-11840 13 p.

Research output: Contribution to journalArticle

78 Scopus citations

Combining prediction, computation and experiment for the characterization of protein disorder

Bracken, C., Iakoucheva, L. M., Romero, P. R. & Dunker, A. K., Oct 1 2004, In : Current Opinion in Structural Biology. 14, 5, p. 570-576 7 p.

Research output: Contribution to journalReview article

104 Scopus citations

Comments on filamentous phage assembly.

Dunker, A. K., Dec 1 1981, In : Progress in clinical and biological research. 64, p. 383-388 6 p.

Research output: Contribution to journalArticle

Comparing NMR and X-ray protein structure: Lindemann-like parameters and NMR disorder

Faraggi, E., Dunker, A., Sussman, J. L. & Kloczkowski, A., Aug 8 2017, (Accepted/In press) In : Journal of Biomolecular Structure and Dynamics. p. 1-11 11 p.

Research output: Contribution to journalArticle

3 Scopus citations

Comparing predictors of disordered protein.

Li, X., Obradovic, Z., Brown, C. J., Garner, E. C. & Dunker, A. K., 2000, In : Genome informatics. Workshop on Genome Informatics. 11, p. 172-184 13 p.

Research output: Contribution to journalArticle

34 Scopus citations

Comparing skeletal and cardiac calsequestrin structures and their calcium binding: A proposed mechanism for coupled calcium binding and protein polymerization

Park, H. J., Park, Y. I., Kim, E. J., Youn, B., Fields, K., Dunker, A. K. & Kang, C. H., Apr 23 2004, In : Journal of Biological Chemistry. 279, 17, p. 18026-18033 8 p.

Research output: Contribution to journalArticle

109 Scopus citations