A. Dunker

  • 31362 Citations
  • 84 h-Index
1969 …2020

Research output per year

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Publications

2013

Interplay between estrogen receptor and AKT in Estradiol-induced alternative splicing

Bhat-Nakshatri, P., Song, E. K., Collins, N. R., Uversky, V. N., Dunker, A. K., O'Malley, B. W., Geistlinger, T. R., Carroll, J. S., Brown, M. & Nakshatri, H., Jun 13 2013, In : BMC Medical Genomics. 6, 1, 21.

Research output: Contribution to journalArticle

13 Scopus citations

Intrinsically disordered regions of p53 family are highly diversified in evolution

Xue, B., Brown, C. J., Dunker, A. K. & Uversky, V. N., Apr 1 2013, In : Biochimica et Biophysica Acta - Proteins and Proteomics. 1834, 4, p. 725-738 14 p.

Research output: Contribution to journalArticle

43 Scopus citations

Pacific symposium on biocomputing 2013

Altman, R. B., Dunker, A. K., Hunter, L. & Klein, T. E., Jan 1 2013, In : Pacific Symposium on Biocomputing. p. 1-4 4 p.

Research output: Contribution to journalEditorial

Prediction of intrinsic disorder in MERS-CoV/HCoV-EMC supports a high oral-fecal transmission

Goh, G. K. M., Dunker, A. & Uversky, V., 2013, In : PLoS Currents. 5, Outbreaks

Research output: Contribution to journalArticle

28 Scopus citations

Sequences and topology: Disorder, modularity, and post/pre translation modification

Gough, J. & Dunker, A. K., Jun 1 2013, In : Current Opinion in Structural Biology. 23, 3, p. 417-419 3 p.

Research output: Contribution to journalEditorial

4 Scopus citations

Stochastic machines as a colocalization mechanism for scaffold protein function

Xue, B., Romero, P. R., Noutsou, M., Maurice, M. M., Rüdiger, S. G. D., William, A. M., Mizianty, M. J., Kurgan, L., Uversky, V. N. & Dunker, A. K., Jun 5 2013, In : FEBS Letters. 587, 11, p. 1587-1591 5 p.

Research output: Contribution to journalArticle

26 Scopus citations
60 Scopus citations

Utilization of protein intrinsic disorder knowledge in structural proteomics

Oldfield, C. J., Xue, B., Van, Y. Y., Ulrich, E. L., Markley, J. L., Dunker, A. K. & Uversky, V. N., Feb 1 2013, In : Biochimica et Biophysica Acta - Proteins and Proteomics. 1834, 2, p. 487-498 12 p.

Research output: Contribution to journalArticle

32 Scopus citations
2012

Binding promiscuity of unfolded peptides

Oldfield, C. J., Xue, B., Dunker, A. K. & Uversky, V. N., Feb 22 2012, Protein and Peptide Folding, Misfolding, and Non-Folding. John Wiley and Sons, p. 239-277 39 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

Erratum: A protein domain-based interactome network for C. elegans early embryogenesis (Cell (2008) 134 (534-545))

Boxem, M., Maliga, Z., Klitgord, N., Li, N., Lemmens, I., Mana, M., De Lichtervelde, L., Mul, J. D., Van De Peut, D., Devos, M., Simonis, N., Yildirim, M. A., Cokol, M., Kao, H. L., De Smet, A. S., Wang, H., Schlaitz, A. L., Hao, T., Milstein, S., Fan, C. & 17 others, Tipsword, M., Drew, K., Galli, M., Rhrissorrakrai, K., Drechsel, D., Koller, D., Roth, F. P., Iakoucheva, L. M., Dunker, A. K., Bonneau, R., Gunsalus, K. C., Hill, D. E., Piano, F., Tavernier, J., Van Den Heuvel, S., Hyman, A. A. & Vidal, M., Dec 21 2012, In : Cell. 151, 7, 1 p.

Research output: Contribution to journalComment/debate

2 Scopus citations

High-throughput characterization of intrinsic disorder in proteins from the Protein Structure Initiative

Johnson, D. E., Xue, B., Sickmeier, M. D., Meng, J., Cortese, M. S., Oldfield, C. J., Le Gall, T., Dunker, A. K. & Uversky, V. N., Oct 1 2012, In : Journal of Structural Biology. 180, 1, p. 201-215 15 p.

Research output: Contribution to journalArticle

26 Scopus citations

Intrinsically disordered proteins: Analysis, prediction, simulation, and biology

Chen, J., Cheng, J. & Dunker, A. K., Jan 1 2012, In : Pacific Symposium on Biocomputing. p. 67-69 3 p.

Research output: Contribution to journalEditorial

2 Scopus citations

Intrinsically disordered proteins

Uversky, V. N. & Dunker, A. K., Dec 1 2012, Comprehensive Biophysics. Elsevier Inc., Vol. 3. p. 170-211 42 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

Intrinsic protein disorder and protein-protein interactions

Hsu, W. L., Oldfield, C., Meng, J., Huang, F., Xue, B., Uversky, V. N., Romero, P. & Dunker, A. K., Jan 1 2012, In : Pacific Symposium on Biocomputing. p. 116-127 12 p.

Research output: Contribution to journalConference article

50 Scopus citations

Molecular profiling - An essential technology enabling personalized medicine in breast cancer

Liu, J., Li, S., Dunker, A. K. & Uversky, V. N., Apr 1 2012, In : Current Drug Targets. 13, 4, p. 541-554 14 p.

Research output: Contribution to journalArticle

5 Scopus citations

MoRFpred, a computational tool for sequence-based prediction and characterization of short disorder-to-order transitioning binding regions in proteins

Disfani, F. M., Hsu, W. L., Mizianty, M. J., Oldfield, C. J., Xue, B., Keith Dunker, A., Uversky, V. N. & Kurgan, L., Jun 1 2012, In : Bioinformatics. 28, 12, p. i75-i83 bts209.

Research output: Contribution to journalArticle

199 Scopus citations

Multiparametric analysis of intrinsically disordered proteins: Looking at intrinsic disorder through compound eyes

Uversky, V. N. & Dunker, A. K., Mar 6 2012, In : Analytical Chemistry. 84, 5, p. 2096-2104 9 p.

Research output: Contribution to journalReview article

56 Scopus citations
264 Scopus citations

Pacific symposium on biocomputing 2012

Altman, R. B., Dunker, A., Hunter, L. & Klein, T. E., 2012, In : Unknown Journal. p. v-vi

Research output: Contribution to journalArticle

Preface

Uversky, V. N. & Dunker, A., 2012, In : Methods in molecular biology (Clifton, N.J.). 895

Research output: Contribution to journalArticle

Proline rich motifs as drug targets in immune mediated disorders

Srinivasan, M. & Dunker, A. K., Jun 20 2012, In : International Journal of Peptides. 2012, 634769.

Research output: Contribution to journalReview article

16 Scopus citations

Protein intrinsic disorder and induced pluripotent stem cells

Xue, B., Oldfield, C. J., Van, Y. Y., Dunker, A. K. & Uversky, V. N., Jan 1 2012, In : Molecular BioSystems. 8, 1, p. 134-150 17 p.

Research output: Contribution to journalReview article

24 Scopus citations

Secondary Structure, a Missing Component of Sequence-Based Minimotif Definitions

Sargeant, D. P., Gryk, M. R., Maciejewski, M. W., Thapar, V., Kundeti, V., Rajasekaran, S., Romero, P., Dunker, K., Li, S. C., Kaneko, T. & Schiller, M. R., Dec 7 2012, In : PLoS ONE. 7, 12, e49957.

Research output: Contribution to journalReview article

6 Scopus citations

Spine-d: Accurate prediction of short and long disordered regions by a single neural-network based method

Zhang, T., Faraggi, E., Xue, B., Dunker, A. K., Uversky, V. N. & Zhou, Y., Feb 2012, In : Journal of Biomolecular Structure and Dynamics. 29, 4, p. 799-813 15 p.

Research output: Contribution to journalArticle

102 Scopus citations

Structural basis for activation of calcineurin by calmodulin

Rumi-Masante, J., Rusinga, F. I., Lester, T. E., Dunlap, T. B., Williams, T. D., Dunker, A. K., Weis, D. D. & Creamer, T. P., Jan 13 2012, In : Journal of molecular biology. 415, 2, p. 307-317 11 p.

Research output: Contribution to journalArticle

51 Scopus citations

Subclassifying disordered proteins by the CH-CDF plot method

Huang, F., Oldfield, C., Meng, J., Hsu, W. L., Xue, B., Uversky, V. N., Romero, P. & Dunker, A. K., Jan 1 2012, In : Pacific Symposium on Biocomputing. p. 128-139 12 p.

Research output: Contribution to journalConference article

49 Scopus citations

Sweeping away protein aggregation with entropic bristles: Intrinsically disordered protein fusions enhance soluble expression

Santner, A. A., Croy, C. H., Vasanwala, F. H., Uversky, V. N., Van, Y. Y. J. & Dunker, A. K., Sep 18 2012, In : Biochemistry. 51, 37, p. 7250-7262 13 p.

Research output: Contribution to journalArticle

58 Scopus citations

The roles of intrinsic disorder in orchestrating the wnt-pathway

Xue, B., Dunker, A. K. & Uversky, V. N., Apr 2012, In : Journal of Biomolecular Structure and Dynamics. 29, 5, p. 843-861 19 p.

Research output: Contribution to journalArticle

31 Scopus citations

Uncertainty analysis in protein disorder prediction

Ghalwash, M. F., Dunker, A. K. & Obradović, Z., Jan 1 2012, In : Molecular BioSystems. 8, 1, p. 381-391 11 p.

Research output: Contribution to journalArticle

8 Scopus citations

Why are we Interested in the Unfolded Peptides and Proteins?

Uversky, V. N. & Dunker, A. K., Feb 22 2012, Protein and Peptide Folding, Misfolding, and Non-Folding. John Wiley and Sons, p. 1-54 54 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

4 Scopus citations
2011

Abundance and functional roles of intrinsic disorder in allergenic proteins and allergen representative peptides

Xue, B., Soeria-Atmadja, D., Gustafsson, M. G., Hammerling, U., Dunker, A. K. & Uversky, V. N., Sep 1 2011, In : Proteins: Structure, Function and Bioinformatics. 79, 9, p. 2595-2606 12 p.

Research output: Contribution to journalArticle

5 Scopus citations

A functionally required unfoldome from the plant kingdom: Intrinsically disordered N-terminal domains of GRAS proteins are involved in molecular recognition during plant development

Sun, X., Xue, B., Jones, W. T., Rikkerink, E., Dunker, A. K. & Uversky, V. N., Oct 1 2011, In : Plant Molecular Biology. 77, 3, p. 205-223 19 p.

Research output: Contribution to journalArticle

78 Scopus citations

Changes in predicted protein disorder tendency may contribute to disease risk

Hu, Y., Liu, Y., Jung, J., Dunker, A. K. & Wang, Y., Dec 23 2011, In : BMC genomics. 12, SUPPL. 5, S2.

Research output: Contribution to journalArticle

9 Scopus citations

Do Viral Proteins Possess Unique Features?

Xue, B., Williams, R. W., Oldfield, C. J., Goh, G. K. M., Dunker, A. K. & Uversky, V. N., Oct 24 2011, Flexible Viruses: Structural Disorder in Viral Proteins. John Wiley and Sons, p. 1-34 34 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

2 Scopus citations

Erratum: (Biophysical Journal)

Morales, C., Oldfield, C. J., Hsu, W. L., Huang, F., Meng, J., Wagle, M. R., Rehlander, R. J., Williams, R. W., Peyetti, S., Xia, Y., Obradovic, Z., Uversky, V. N. & Keith Dunker, A., May 4 2011, In : Biophysical journal. 100, 9, 1 p.

Research output: Contribution to journalComment/debate

Erratum: (Biophysical Journal)

Huang, F., Oldfield, C. J., Bin, X., Meng, J., Hsu, W., Uversky, V. N. & Keith Dunker, A., May 4 2011, In : Biophysical journal. 100, 9, 1 p.

Research output: Contribution to journalComment/debate

Erratum: (Biophysical Journal)

Hsu, W. L., Oldfield, C. J., Xue, B., Wagle, M., Meng, J., Huang, F., Morales, C., Uversky, V. N. & Keith Dunker, A., May 4 2011, In : Biophysical journal. 100, 9, 1 p.

Research output: Contribution to journalComment/debate

Evolution and disorder

Brown, C. J., Johnson, A. K., Dunker, A. K. & Daughdrill, G. W., Jun 1 2011, In : Current Opinion in Structural Biology. 21, 3, p. 441-446 6 p.

Research output: Contribution to journalReview article

150 Scopus citations

In-silico prediction of disorder content using hybrid sequence representation

Mizianty, M. J., Zhang, T., Xue, B., Zhou, Y., Dunker, A. K., Uversky, V. N. & Kurgan, L., Jun 17 2011, In : BMC bioinformatics. 12, 245.

Research output: Contribution to journalArticle

30 Scopus citations

Phosphorylation of human calsequestrin: Implications for calcium regulation

Sanchez, E. J., Munske, G. R., Criswell, A., Milting, H., Dunker, A. K. & Kang, C., Jul 2011, In : Molecular and Cellular Biochemistry. 353, 1-2, p. 195-204 10 p.

Research output: Contribution to journalArticle

12 Scopus citations

Predictive power estimation algorithm (PPEA) - a new algorithm to reduce overfitting for genomic biomarker discovery

Liu, J., Jolly, R. A., Smith, A. T., Searfoss, G. H., Goldstein, K. M., Uversky, V. N., Dunker, K., Li, S., Thomas, C. E. & Wei, T., Sep 15 2011, In : PloS one. 6, 9, e24233.

Research output: Contribution to journalArticle

7 Scopus citations

Regions of intrinsic disorder help identify a novel nuclear localization signal in Toxoplasma gondii histone acetyltransferase TgGCN5-B

Dixon, S. E., Bhatti, M. M., Uversky, V. N., Dunker, A. K. & Sullivan, W. J., Feb 1 2011, In : Molecular and Biochemical Parasitology. 175, 2, p. 192-195 4 p.

Research output: Contribution to journalArticle

14 Scopus citations

Sequences and topology: Intrinsic disorder in the evolving universe of protein structure

Dunker, A. K. & Gough, J., Jun 1 2011, In : Current Opinion in Structural Biology. 21, 3, p. 379-381 3 p.

Research output: Contribution to journalEditorial

16 Scopus citations

Structural Disorder in Matrix Proteins of HIV-Related Viruses

Goh, G. K. M., Xue, B., Dunker, A. K. & Uversky, V. N., Oct 24 2011, Flexible Viruses: Structural Disorder in Viral Proteins. John Wiley and Sons, p. 143-167 25 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

Structural Disorder in Proteins from Influenza Virus

Goh, G. M., Xue, B., Dunker, A. K. & Uversky, V. N., Oct 24 2011, Flexible Viruses: Structural Disorder in Viral Proteins. John Wiley and Sons, p. 169-200 32 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

The orderly chaos of proteins

Keith Dunker, A. & Kriwacki, R. W., Apr 1 2011, In : Scientific American. 304, 4, p. 48-53 6 p.

Research output: Contribution to journalArticle

7 Scopus citations

The orderly chaos of proteins.

Dunker, A. K. & Kriwacki, R. W., Apr 1 2011, In : Scientific American. 304, 4, p. 68-73 6 p.

Research output: Contribution to journalArticle

5 Scopus citations
2010

2K09 and thereafter: The coming era of integrative bioinformatics, systems biology and intelligent computing for functional genomics and personalized medicine research

Yang, J. Y., Niemierko, A., Bajcsy, R., Xu, D., Athey, B. D., Zhang, A., Ersoy, O. K., Li, G. Z., Borodovsky, M., Zhang, J. C., Arabnia, H. R., Deng, Y., Dunker, A. K., Liu, Y. & Ghafoor, A., Nov 29 2010, In : BMC genomics. 11, SUPPL. 3, I1.

Research output: Contribution to journalArticle

5 Scopus citations

Archaic chaos: Intrinsically disordered proteins in Archaea

Xue, B., Williams, R. W., Oldfield, C. J., Dunker, A. K. & Uversky, V. N., May 28 2010, In : BMC Systems Biology. 4, SUPPL. 1, S1.

Research output: Contribution to journalArticle

80 Scopus citations

Drugs for 'protein clouds': Targeting intrinsically disordered transcription factors

Dunker, A. K. & Uversky, V. N., Dec 1 2010, In : Current Opinion in Pharmacology. 10, 6, p. 782-788 7 p.

Research output: Contribution to journalReview article

111 Scopus citations