A. Dunker

  • 31362 Citations
  • 84 h-Index
1969 …2020

Research output per year

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Publications

2007

Functional anthology of intrinsic disorder. 2. cellular components, domains, technical terms, developmental processes, and coding sequence diversities correlated with long disordered regions

Vucetic, S., Xie, H., Iakoucheva, L. M., Oldfield, C. J., Dunker, A. K., Obradovic, Z. & Uversky, V. N., May 1 2007, In : Journal of Proteome Research. 6, 5, p. 1899-1916 18 p.

Research output: Contribution to journalArticle

189 Scopus citations

Functional anthology of intrinsic disorder. 3. Ligands, post-translational modifications, and diseases associated with intrinsically disordered proteins

Xie, H., Vucetic, S., Iakoucheva, L. M., Oldfield, C. J., Dunker, A. K., Obradovic, Z. & Uversky, V. N., May 1 2007, In : Journal of Proteome Research. 6, 5, p. 1917-1932 16 p.

Research output: Contribution to journalArticle

276 Scopus citations

Intrinsically disordered proteins: An update

Dunker, A. K., Oldfield, C. J., Meng, J., Romero, P., Yang, J. Y., Obradovic, Z. & Uversky, V. N., Dec 1 2007, Proceedings of the 7th IEEE International Conference on Bioinformatics and Bioengineering, BIBE. p. 49-58 10 p. 4375544. (Proceedings of the 7th IEEE International Conference on Bioinformatics and Bioengineering, BIBE).

Research output: Chapter in Book/Report/Conference proceedingConference contribution

1 Scopus citations

Intrinsic disorder and functional proteomics

Radivojac, P., Iakoucheva, L. M., Oldfield, C. J., Obradovic, Z., Uversky, V. N. & Dunker, A. K., Mar 2007, In : Biophysical journal. 92, 5, p. 1439-1456 18 p.

Research output: Contribution to journalArticle

509 Scopus citations

Intrinsic disorder in the protein data bank

Gall, T. L., Romero, P. R., Cortese, M. S., Uversky, V. N. & Dunker, A. K., Feb 2007, In : Journal of Biomolecular Structure and Dynamics. 24, 4, p. 325-341 17 p.

Research output: Contribution to journalArticle

97 Scopus citations

Mining α-helix-forming molecular recognition features with cross species sequence alignments

Cheng, Y., Oldfield, C. J., Meng, J., Romero, P., Uversky, V. N. & Dunker, A. K., Nov 27 2007, In : Biochemistry. 46, 47, p. 13468-13477 10 p.

Research output: Contribution to journalArticle

217 Scopus citations

Pacific symposium on biocomputing 2007

Altman, R. B., Keith Dunker, A., Hunter, L. & Klein, T. E., Dec 1 2007, In : Pacific Symposium on Biocomputing 2007, PSB 2007. p. v-vii

Research output: Contribution to journalEditorial

Prediction of intrinsic disorder and its use in functional proteomics.

Uversky, V. N., Radivojac, P., Iakoucheva, L. M., Obradovic, Z. & Dunker, A. K., 2007, In : Methods in molecular biology (Clifton, N.J.). 408, p. 69-92 24 p.

Research output: Contribution to journalArticle

30 Scopus citations

Structural basis for regulation of protein phosphatase 1 by inhibitor-2

Hurley, T. D., Yang, J., Zhang, L., Goodwin, K. D., Zou, Q., Cortese, M., Dunker, A. K. & DePaoli-Roach, A. A., Sep 28 2007, In : Journal of Biological Chemistry. 282, 39, p. 28874-28883 10 p.

Research output: Contribution to journalArticle

128 Scopus citations
2006

Abundance of intrinsic disorder in protein associated with cardiovascular disease

Cheng, Y., LeGall, T., Oldfield, C. J., Dunker, A. K. & Uversky, V. N., Sep 5 2006, In : Biochemistry. 45, 35, p. 10448-10460 13 p.

Research output: Contribution to journalArticle

128 Scopus citations

Alternative splicing in concert with protein intrinsic disorder enables increased functional diversity in multicellular organisms

Romero, P. R., Zaidi, S., Fang, Y. Y., Uversky, V. N., Radivojac, P., Oldfield, C. J., Cortese, M. S., Sickmeier, M., LeGall, T., Obradovic, Z. & Dunker, A. K., May 30 2006, In : Proceedings of the National Academy of Sciences of the United States of America. 103, 22, p. 8390-8395 6 p.

Research output: Contribution to journalArticle

291 Scopus citations

Analysis of Molecular Recognition Features (MoRFs)

Mohan, A., Oldfield, C. J., Radivojac, P., Vacic, V., Cortese, M. S., Dunker, A. K. & Uversky, V. N., Oct 6 2006, In : Journal of molecular biology. 362, 5, p. 1043-1059 17 p.

Research output: Contribution to journalArticle

483 Scopus citations

Calmodulin signaling: Analysis and prediction of a disorder-dependent molecular recognition

Radivojac, P., Vucetic, S., O'Connor, T. R., Uversky, V. N., Obradovic, Z. & Dunker, A. K., May 1 2006, In : Proteins: Structure, Function and Genetics. 63, 2, p. 398-410 13 p.

Research output: Contribution to journalArticle

84 Scopus citations

Conservation of intrinsic disorder in protein domains and families: I. A database of conserved predicted disordered regions

Chen, J. W., Romero, P., Uversky, V. N. & Dunker, A. K., Apr 1 2006, In : Journal of Proteome Research. 5, 4, p. 879-887 9 p.

Research output: Contribution to journalArticle

91 Scopus citations

Conservation of intrinsic disorder in protein domains and families: II. Functions of conserved disorder

Chen, J. W., Romero, P., Uversky, V. N. & Dunker, A. K., Apr 1 2006, In : Journal of Proteome Research. 5, 4, p. 888-898 11 p.

Research output: Contribution to journalArticle

95 Scopus citations

Disorder and sequence repeats in hub proteins and their implications for network evolution

Dosztányi, Z., Chen, J., Dunker, A. K., Simon, I. & Tompa, P., Nov 1 2006, In : Journal of Proteome Research. 5, 11, p. 2985-2995 11 p.

Research output: Contribution to journalArticle

241 Scopus citations

Intrinsic disorder in transcription factors

Liu, J., Perumal, N. B., Oldfield, C. J., Su, E. W., Uversky, V. N. & Dunker, A. K., Jun 6 2006, In : Biochemistry. 45, 22, p. 6873-6888 16 p.

Research output: Contribution to journalArticle

382 Scopus citations

Length-dependent prediction of protein in intrinsic disorder

Peng, K., Radivojac, P., Vucetic, S., Dunker, A. K. & Obradovic, Z., Apr 17 2006, In : BMC bioinformatics. 7, 208.

Research output: Contribution to journalArticle

525 Scopus citations

Pacific symposium on biocomputing 2006

Altman, R. B., Keith Dunker, A., Hunter, L. & Klein, T. E., Dec 1 2006, In : Proceedings of the Pacific Symposium on Biocomputing 2006, PSB 2006. p. v-vii

Research output: Contribution to journalEditorial

Protein intrinsic disorder and human papillomaviruses: Increased amount of disorder in E6 and E7 oncoproteins from high risk HPVs

Uversky, V. N., Roman, A., Oldfield, C. J. & Dunker, A. K., Aug 1 2006, In : Journal of Proteome Research. 5, 8, p. 1829-1842 14 p.

Research output: Contribution to journalArticle

106 Scopus citations

Rational drug design via intrinsically disordered protein

Cheng, Y., LeGall, T., Oldfield, C. J., Mueller, J. P., Van, Y. Y. J., Romero, P., Cortese, M. S., Uversky, V. N. & Dunker, A. K., Oct 1 2006, In : Trends in Biotechnology. 24, 10, p. 435-442 8 p.

Research output: Contribution to journalArticle

176 Scopus citations
2005

Addressing the intrinsic disorder bottleneck in structural proteomics

Oldfield, C. J., Ulrich, E. L., Cheng, Y., Dunker, A. K. & Markley, J. L., May 15 2005, In : Proteins: Structure, Function and Genetics. 59, 3, p. 444-453 10 p.

Research output: Contribution to journalArticle

69 Scopus citations

Coupled folding and binding with α-helix-forming molecular recognition elements

Oldfield, C. J., Cheng, Y., Cortese, M. S., Romero, P., Uversky, V. N. & Dunker, A. K., Sep 20 2005, In : Biochemistry. 44, 37, p. 12454-12470 17 p.

Research output: Contribution to journalArticle

451 Scopus citations

DisProt: A database of protein disorder

Vucetic, S., Obradovic, Z., Vacic, V., Radivojac, P., Peng, K., Iakoucheva, L. M., Cortese, M. S., Lawson, J. D., Brown, C. J., Sikes, J. G., Newton, C. D. & Dunker, A. K., Jan 1 2005, In : Bioinformatics. 21, 1, p. 137-140 4 p.

Research output: Contribution to journalArticle

171 Scopus citations

Exploiting heterogeneous sequence properties improves prediction of protein disorder

Obradovic, Z., Peng, K., Vucetic, S., Radivojac, P. & Dunker, A. K., Dec 1 2005, In : Proteins: Structure, Function and Genetics. 61, SUPPL. 7, p. 176-182 7 p.

Research output: Contribution to journalArticle

359 Scopus citations

Flexible nets: The roles of intrinsic disorder in protein interaction networks

Dunker, A. K., Cortese, M. S., Romero, P., Iakoucheva, L. M. & Uversky, V. N., Oct 1 2005, In : FEBS Journal. 272, 20, p. 5129-5148 20 p.

Research output: Contribution to journalShort survey

796 Scopus citations

Improving protein secondary-structure prediction by predicting ends of secondary-structure segments

Midic, U., Dunker, A. K. & Obradovic, Z., Dec 1 2005, Proceedings of the 2005 IEEE Symposium on Computational Intelligence in Bioinformatics and Computational Biology, CIBCB '05. 1594959. (Proceedings of the 2005 IEEE Symposium on Computational Intelligence in Bioinformatics and Computational Biology, CIBCB '05; vol. 2005).

Research output: Chapter in Book/Report/Conference proceedingConference contribution

4 Scopus citations

Interaction between cardiac calsequestrin and drugs with known cardiotoxicity

Park, I. Y., Kim, E. J., Park, H. J., Fields, K., Dunker, A. K. & Kang, C. H., Jan 1 2005, In : Molecular Pharmacology. 67, 1, p. 97-104 8 p.

Research output: Contribution to journalArticle

38 Scopus citations

Intrinsic disorder and prote in modifications: Building an SVM predictor for methylation

Daily, K. M., Radivojac, P. & Dunker, A. K., Dec 1 2005, Proceedings of the 2005 IEEE Symposium on Computational Intelligence in Bioinformatics and Computational Biology, CIBCB '05. 1594957. (Proceedings of the 2005 IEEE Symposium on Computational Intelligence in Bioinformatics and Computational Biology, CIBCB '05; vol. 2005).

Research output: Chapter in Book/Report/Conference proceedingConference contribution

39 Scopus citations

Optimizing long intrinsic disorder predictors with protein evolutionary information

Peng, K., Vucetic, S., Radivojac, P., Brown, C. J., Dunker, A. K. & Obradovic, Z., Feb 1 2005, In : Journal of bioinformatics and computational biology. 3, 1, p. 35-60 26 p.

Research output: Contribution to journalArticle

280 Scopus citations

Pacific symposium on biocomputing 2005

Altman, R. B., Dunker, A. K., Hunter, L. & Klein, T. E., Dec 1 2005, In : Proceedings of the Pacific Symposium on Biocomputing 2005, PSB 2005. p. v-vii

Research output: Contribution to journalEditorial

Showing your ID: Intrinsic disorder as an ID for recognition, regulation and cell signaling

Uversky, V. N., Oldfield, C. J. & Dunker, A. K., Sep 1 2005, In : Journal of Molecular Recognition. 18, 5, p. 343-384 42 p.

Research output: Contribution to journalReview article

607 Scopus citations

Uncovering the unfoldome: Enriching cell extracts for unstructured proteins by acid treatment

Cortese, M. S., Baird, J. P., Uversky, V. N. & Dunker, A. K., Sep 1 2005, In : Journal of Proteome Research. 4, 5, p. 1610-1618 9 p.

Research output: Contribution to journalArticle

51 Scopus citations
2004

Classification and knowledge discovery in protein databases

Radivojac, P., Chawla, N. V., Dunker, A. K. & Obradovic, Z., Aug 1 2004, In : Journal of biomedical informatics. 37, 4, p. 224-239 16 p.

Research output: Contribution to journalArticle

63 Scopus citations

Combining prediction, computation and experiment for the characterization of protein disorder

Bracken, C., Iakoucheva, L. M., Romero, P. R. & Dunker, A. K., Oct 1 2004, In : Current Opinion in Structural Biology. 14, 5, p. 570-576 7 p.

Research output: Contribution to journalReview article

104 Scopus citations

Comparing skeletal and cardiac calsequestrin structures and their calcium binding: A proposed mechanism for coupled calcium binding and protein polymerization

Park, H. J., Park, Y. I., Kim, E. J., Youn, B., Fields, K., Dunker, A. K. & Kang, C. H., Apr 23 2004, In : Journal of Biological Chemistry. 279, 17, p. 18026-18033 8 p.

Research output: Contribution to journalArticle

109 Scopus citations

Feature selection filters based on the permutation test

Radivojac, P., Obradovic, Z., Dunker, A. & Vucetic, S., 2004, Lecture Notes in Artificial Intelligence (Subseries of Lecture Notes in Computer Science). Boulicaut, J-F., Esposito, F., Pedreschi, D. & Giannotti, F. (eds.). Vol. 3201. p. 334-346 13 p.

Research output: Chapter in Book/Report/Conference proceedingConference contribution

27 Scopus citations

Natively disordered proteins: Functions and predictions

Romero, P., Obradovic, Z. & Dunker, A. K., Dec 1 2004, In : Applied Bioinformatics. 3, 2-3, p. 105-113 9 p.

Research output: Contribution to journalArticle

114 Scopus citations

Protein flexibility and intrinsic disorder

Radivojac, P., Obradovic, Z., Smith, D. K., Zhu, G., Vucetic, S., Brown, C. J., Lawson, J. D. & Dunker, A. K., Jan 1 2004, In : Protein Science. 13, 1, p. 71-80 10 p.

Research output: Contribution to journalArticle

225 Scopus citations

The C-terminal domain of measles virus nucleoprotein belongs to the class of intrinsically disordered proteins that fold upon binding to their physiological partner

Bourhis, J. M., Johansson, K., Receveur-Bréchot, V., Oldfield, C. J., Dunker, K. A., Canard, B. & Longhi, S., Feb 2004, In : Virus Research. 99, 2, p. 157-167 11 p.

Research output: Contribution to journalArticle

136 Scopus citations

The importance of intrinsic disorder for protein phosphorylation

Iakoucheva, L. M., Radivojac, P., Brown, C. J., O'Connor, T. R., Sikes, J. G., Obradovic, Z. & Dunker, A. K., Jul 14 2004, In : Nucleic acids research. 32, 3, p. 1037-1049 13 p.

Research output: Contribution to journalArticle

971 Scopus citations
2003

Erratum: Isolation of chloroform-resistant mutants of filamentous phage: Localization in models of phage structure (Journal of Molecular Biology (1999) 287 (449-457))

Oh, J. S., Davies, D. R., Lawson, J. D., Arnold, G. E. & Dunker, A. K., Nov 14 2003, In : Journal of molecular biology. 334, 1, p. 173-174 2 p.

Research output: Contribution to journalComment/debate

Erratum: Polymerization of calsequestrin. Implications for Ca2+ regulation (The Journal of Biological Chemistry (2003) 278 (16176-16182))

Park, H. J., Wu, S., Dunker, A. K. & Kang, C. H., Oct 24 2003, In : Journal of Biological Chemistry. 278, 43, 1 p.

Research output: Contribution to journalComment/debate

Flavors of protein disorder

Vucetic, S., Brown, C. J., Dunker, A. K. & Obradovic, Z., Sep 1 2003, In : Proteins: Structure, Function and Genetics. 52, 4, p. 573-584 12 p.

Research output: Contribution to journalArticle

298 Scopus citations

Improved amino acid flexibility parameters

Smith, D. K., Radivojac, P., Obradovic, Z., Dunker, A. K. & Zhu, G., May 1 2003, In : Protein Science. 12, 5, p. 1060-1072 13 p.

Research output: Contribution to journalArticle

114 Scopus citations

Ligand and flavor binding functional properties of β-lactoglobulin in the molten globule state induced by high pressure

Yang, J., Powers, J. R., Clark, S., Dunker, A. K. & Swanson, B. G., Mar 2003, In : Journal of Food Science. 68, 2, p. 444-452 9 p.

Research output: Contribution to journalArticle

26 Scopus citations

Order, disorder, and flexibility: Prediction from protein sequence

Iakoucheva, L. M. & Dunker, A. K., Nov 2003, In : Structure. 11, 11, p. 1316-1317 2 p.

Research output: Contribution to journalReview article

38 Scopus citations

Polymerization of calsequestrin: Implications for Ca2+ regulation

Park, H. J., Wu, S., Dunker, A. K. & Kang, C. H., May 2 2003, In : Journal of Biological Chemistry. 278, 18, p. 16176-16182 7 p.

Research output: Contribution to journalArticle

88 Scopus citations

Predicting Intrinsic Disorder From Amino Acid Sequence

Obradovic, Z., Peng, K., Vucetic, S., Radivojac, P., Brown, C. J. & Dunker, A. K., Nov 12 2003, In : Proteins: Structure, Function and Genetics. 53, SUPPL. 6, p. 566-572 7 p.

Research output: Contribution to journalArticle

311 Scopus citations

Prediction of boundaries between intrinsically ordered and disordered protein regions.

Radivojac, P., Obradović, Z., Brown, C. J. & Dunker, A. K., 2003, In : Pacific Symposium on Biocomputing. Pacific Symposium on Biocomputing. p. 216-227 12 p.

Research output: Contribution to journalArticle

53 Scopus citations