A. Dunker

  • 29187 Citations
  • 82 h-Index
1969 …2019
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Publications 1969 2019

2002
1282 Citations (Scopus)

Intrinsic disorder and protein function

Dunker, A., Brown, C. J., Lawson, J. D., Iakoucheva, L. M. & Obradović, Z., May 28 2002, In : Biochemistry. 41, 21, p. 6573-6582 10 p.

Research output: Contribution to journalArticle

Cytochrome c Group
Clusterin
DNA Helicases
Apoproteins
Molecular Chaperones
813 Citations (Scopus)

Intrinsic disorder in cell-signaling and cancer-associated proteins

Iakoucheva, L. M., Brown, C. J., Lawson, J. D., Obradović, Z. & Dunker, A., 2002, In : Journal of Molecular Biology. 323, 3, p. 573-584 12 p.

Research output: Contribution to journalArticle

Neoplasms
Proteins
Intrinsically Disordered Proteins
Protein Databases
Cytoskeletal Proteins
1 Citation (Scopus)

The benefit of intrinsic disorder information in neural network prediction of calmodulin binding targets

O'Connor, T. R., Lawson, J. D. & Dunker, A., 2002, Proceedings of the International Joint Conference on Neural Networks. Vol. 1. p. 296-299 4 p.

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Calmodulin
Neural networks
Order disorder transitions
Calcium
Proteins
3 Citations (Scopus)

The protein trinity: Importance of intrinsic disorder for protein function

Dunker, A., 2002, In : Human Genome News. 12, 1, p. 13-14 2 p.

Research output: Contribution to journalArticle

Proteins
2001
91 Citations (Scopus)

Aberrant mobility phenomena of the DNA repair protein XPA

Iakoucheva, L. M., Kimzey, A. L., Masselon, C. D., Smith, R. D., Dunker, A. & Ackerman, E. J., 2001, In : Protein Science. 10, 7, p. 1353-1362 10 p.

Research output: Contribution to journalArticle

Xenopus
DNA Repair
Repair
DNA
Molecular weight
78 Citations (Scopus)

Clusterin, a binding protein with a molten globule-like region

Bailey, R. W., Dunker, A., Brown, C. J., Garner, E. C. & Griswold, M. D., Oct 2 2001, In : Biochemistry. 40, 39, p. 11828-11840 13 p.

Research output: Contribution to journalArticle

Clusterin
Molten materials
Carrier Proteins
Proteins
Trypsin
82 Citations (Scopus)

Identification of intrinsic order and disorder in the DNA repair protein XPA

Iakoucheva, L. M., Kimzey, A. L., Masselon, C. D., Bruce, J. E., Garner, E. C., Brown, C. J., Dunker, A., Smith, R. D. & Ackerman, E. J., 2001, In : Protein Science. 10, 3, p. 560-571 12 p.

Research output: Contribution to journalArticle

Proteolysis
Xenopus
DNA Repair
Repair
Trypsin
1473 Citations (Scopus)

Intrinsically disordered protein

Dunker, A., Lawson, J. D., Brown, C. J., Williams, R. M., Romero, P., Oh, J. S., Oldfield, C. J., Campen, A. M., Ratliff, C. M., Hipps, K. W., Ausio, J., Nissen, M. S., Reeves, R., Kang, C., Kissinger, C. R., Bailey, R. W., Griswold, M. D., Chiu, W., Garner, E. C. & Obradovic, Z., 2001, In : Journal of Molecular Graphics and Modelling. 19, 1, p. 26-59 34 p.

Research output: Contribution to journalArticle

Intrinsically Disordered Proteins
proteins
Proteins
disorders
Molten materials
14 Citations (Scopus)

Methods for improving protein disorder prediction

Vucetic, S., Radivojac, P., Obradovic, Z., Brown, C. J. & Dunker, A., 2001, Proceedings of the International Joint Conference on Neural Networks. Vol. 4. p. 2718-2723 6 p.

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Proteins
Classifiers
Neural networks
Logistics
1045 Citations (Scopus)

Sequence complexity of disordered protein

Romero, P., Obradovic, Z., Li, X., Garner, E. C., Brown, C. J. & Dunker, A., 2001, In : Proteins: Structure, Function and Genetics. 42, 1, p. 38-48 11 p.

Research output: Contribution to journalArticle

Proteins
Amino Acids
Intrinsically Disordered Proteins
Protein Databases
Entropy
23 Citations (Scopus)

The power to detect recombination using the coalescent [3]

Brown, C. J., Garner, E. C., Dunker, A. & Joyce, P., 2001, In : Molecular Biology and Evolution. 18, 7, p. 1421-1424 4 p.

Research output: Contribution to journalArticle

Gene Conversion
141 Citations (Scopus)

The protein non-folding problem: amino acid determinants of intrinsic order and disorder.

Williams, R. M., Obradovi, Z., Mathura, V., Braun, W., Garner, E. C., Young, J., Takayama, S., Brown, C. J. & Dunker, A., 2001, Pacific Symposium on Biocomputing. Pacific Symposium on Biocomputing. p. 89-100 12 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

Protein Folding
Databases
Amino Acids
Circular Dichroism
Intrinsically Disordered Proteins
435 Citations (Scopus)

The protein trinity - Linking function and disorder

Dunker, A. & Obradovic, Z., 2001, In : Nature Biotechnology. 19, 9, p. 805-806 2 p.

Research output: Contribution to journalArticle

Biological Models
Protein Conformation
Structure-Activity Relationship
Biotechnology
Transcription Factors
73 Citations (Scopus)

β-Lactoglobulin molten globule induced by high pressure

Yang, J., Dunker, A., Powers, J. R., Clark, S. & Swanson, B. G., 2001, In : Journal of Agricultural and Food Chemistry. 49, 7, p. 3236-3243 8 p.

Research output: Contribution to journalArticle

lactoglobulins
Lactoglobulins
Hydrostatic Pressure
high pressure treatment
Hydrostatic pressure
2000
34 Citations (Scopus)

Comparing predictors of disordered protein.

Li, X., Obradovic, Z., Brown, C. J., Garner, E. C. & Dunker, A., 2000, In : Genome informatics. Workshop on Genome Informatics. 11, p. 172-184 13 p.

Research output: Contribution to journalArticle

Amino Acids
Amino Acid Sequence
Proteins
Logistic Models
29 Citations (Scopus)

Intelligent data analysis for protein disorder prediction

Romero, P., Obradovic, Z. & Dunker, A., Dec 2000, In : Artificial Intelligence Review. 14, 6, p. 447-484 38 p.

Research output: Contribution to journalArticle

data analysis
data bank
Proteins
Swiss
biotechnology
514 Citations (Scopus)

Intrinsic protein disorder in complete genomes.

Dunker, A., Obradovic, Z., Romero, P., Garner, E. C. & Brown, C. J., 2000, In : Genome informatics. Workshop on Genome Informatics. 11, p. 161-171 11 p.

Research output: Contribution to journalArticle

Archaea
Genome
Bacteria
Proteins
Plasmodium
63 Citations (Scopus)

Isolation and characterization of cDNAs expressed in the early stages of flavonol-induced pollen germination in petunia

Guyon, V. N., Astwood, J. D., Garner, E. C., Dunker, A. & Taylor, L. P., 2000, In : Plant Physiology. 123, 2, p. 699-710 12 p.

Research output: Contribution to journalArticle

Petunia
pollen germination
Germination
Pollen
flavonols
1999
64 Citations (Scopus)

Folding minimal sequences: The lower bound for sequence complexity of globular proteins

Romero, P., Obradovic, Z. & Dunker, A., Dec 3 1999, In : FEBS Letters. 462, 3, p. 363-367 5 p.

Research output: Contribution to journalArticle

Protein Folding
Entropy
Proteins
Dimers
11 Citations (Scopus)

Isolation of chloroform-resistant mutants of filamentous phage: Localization in models of phage structure

Oh, J. S., Davies, D. R., Lawson, J. D., Arnold, G. E. & Dunker, A., Apr 2 1999, In : Journal of Molecular Biology. 287, 3, p. 449-457 9 p.

Research output: Contribution to journalArticle

Chloroform
Bacteriophages
Bacteriophage M13
Structural Models
Site-Directed Mutagenesis
1998
183 Citations (Scopus)

Crystal structure of calsequestrin from rabbit skeletal muscle sarcoplasmic reticulum

Wang, S., Trumble, W. R., Liao, H., Wesson, C. R., Dunker, A. & Kang, C., Jun 1998, In : Nature Structural Biology. 5, 6, p. 476-483 8 p.

Research output: Contribution to journalArticle

Calsequestrin
Sarcoplasmic Reticulum
Muscle
Skeletal Muscle
Crystal structure
21 Citations (Scopus)

Effects of relative humidity and applied force on atomic force microscopy images of the filamentous phage fd

Ji, X., Oh, J., Dunker, A. & Hipps, K. W., May 1 1998, In : Ultramicroscopy. 72, 3-4, p. 165-176 12 p.

Research output: Contribution to journalArticle

Bacteriophages
humidity
Atomic force microscopy
Atmospheric humidity
atomic force microscopy
302 Citations (Scopus)

Protein disorder and the evolution of molecular recognition: theory, predictions and observations.

Dunker, A., Garner, E., Guilliot, S., Romero, P., Albrecht, K., Hart, J., Obradovic, Z., Kissinger, C. & Villafranca, J. E., 1998, Pacific Symposium on Biocomputing. Pacific Symposium on Biocomputing. p. 473-484 12 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

Molecular Evolution
Genetic Selection
Sequence Analysis
Proteins
Amino Acids
202 Citations (Scopus)

Thousands of proteins likely to have long disordered regions.

Romero, P., Obradovic, Z., Kissinger, C. R., Villafranca, J. E., Garner, E., Guilliot, S. & Dunker, A., 1998, Pacific Symposium on Biocomputing. Pacific Symposium on Biocomputing. p. 437-448 12 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

Proteins
Protein Databases
Structure-Activity Relationship
Amino Acids
1997
199 Citations (Scopus)

Identifying disordered regions in proteins from amino acid sequence

Romero, P., Obradovi, Z., Kissinger, C., Villafranca, J. E. & Dunker, A., 1997, IEEE International Conference on Neural Networks - Conference Proceedings. IEEE, Vol. 1. p. 90-95 6 p.

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Amino acids
Neural networks
Proteins
Molecular recognition
Carboxylic acids
1996

An introductory course in computation molecular biology: rationale, history, observations, and course description.

Johns, S. J., Thompson, S. M. & Dunker, A., 1996, Pacific Symposium on Biocomputing. Pacific Symposium on Biocomputing. p. 396-407 12 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

Molecular Biology
History
Students
Posters
Computational Biology
4 Citations (Scopus)

Quaternion contact ribbons: a new tool for visualizing intra- and intermolecular interactions in proteins.

Albrecht, K., Hart, J., Shaw, A. & Dunker, A., 1996, Pacific Symposium on Biocomputing. Pacific Symposium on Biocomputing. p. 41-52 12 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

Amino Acid Sequence
Proteins
6 Citations (Scopus)

Relation of β-lactoglobulin - Sodium polypectate aggregation to bulk macromolecular concentration

Ndi, E. E., Swanson, B. G., Dunker, A. & Luedecke, L. O., Jan 1996, In : Journal of Food Science. 61, 1, p. 69-73 5 p.

Research output: Contribution to journalArticle

lactoglobulins
Lactoglobulins
Sodium
sodium
Heating
1995
1 Citation (Scopus)

Identifying repeated structural elements in folded proteins

Miller, R. T., Douthart, R. J. & Dunker, A., 1995, Proceedings of the Hawaii International Conference on System Sciences. Nunamaker, J. F. & Sprague, R. H. J. (eds.). Publ by IEEE, Vol. 5. p. 235-244 10 p.

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Proteins
Amino acids
Polypeptides
Dihedral angle
Specifications

Protein structure prediction. Introduction to session

Dunker, A. & Lathrop, R. H., 1995, Proceedings of the Hawaii International Conference on System Sciences. Nunamaker, J. F. & Sprague, R. H. J. (eds.). Publ by IEEE, Vol. 5. p. 295 1 p.

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Proteins
Protein folding
Molecular biology
DNA sequences
Combinatorial optimization
1994
16 Citations (Scopus)

Evidence that the A2 fragment of Shiga-like toxin type I is required for holotoxin integrity

Austin, P. R., Jablonski, P. E., Bohach, G. A., Dunker, A. & Hovde, C. J., 1994, In : Infection and Immunity. 62, 5, p. 1768-1775 8 p.

Research output: Contribution to journalArticle

Shiga Toxin 1
varespladib methyl
Amino Acids
Vero Cells
Cytotoxins
1 Citation (Scopus)

P22 phage capsids under pressure.

Dunker, A., May 1994, In : Biophysical Journal. 66, 5, p. 1269-1271 3 p.

Research output: Contribution to journalArticle

Bacteriophage P22
Biophysics
Protein Conformation
Capsid
Protein Folding
1993
1 Citation (Scopus)

An alphabet of amino acid conformations in protein

Miller, R. T., Douthart, R. J. & Dunker, A., Jan 1 1993, Proceedings of the 26th Hawaii International Conference on System Sciences, HICSS 1993. IEEE Computer Society, p. 689-698 10 p. 270672. (Proceedings of the Annual Hawaii International Conference on System Sciences; vol. 1).

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Conformations
Amino acids
Proteins
Dihedral angle
Angle measurement
149 Citations (Scopus)

Atomic force microscopy of DNA and bacteriophage in air, water and propanol: The role of adhesion forces

Lyubchenko, Y. L., Oden, P. I., Lampner, D., Lindsay, S. M. & Dunker, A., 1993, In : Nucleic Acids Research. 21, 5, p. 1117-1123 7 p.

Research output: Contribution to journalArticle

1-Propanol
Bacteriophages
Atomic Force Microscopy
Propanol
Adhesion
55 Citations (Scopus)

Ca2+-induced folding and aggregation of skeletal muscle sarcoplasmic reticulum calsequestrin: The involvement of the trifluoperazine-binding site

He, Z., Dunker, A., Wesson, C. R. & Trumble, W. R., Nov 25 1993, In : Journal of Biological Chemistry. 268, 33, p. 24635-24641 7 p.

Research output: Contribution to journalArticle

Calsequestrin
Trifluoperazine
Sarcoplasmic Reticulum
Muscle
Skeletal Muscle
27 Citations (Scopus)

Structural changes accompanying chloroform-induced contraction of the filamentous phage fd

Roberts, L. M. & Dunker, A., 1993, In : Biochemistry. 32, 39, p. 10479-10488 10 p.

Research output: Contribution to journalArticle

Bacteriophage M13
Bacteriophages
Capsid Proteins
Chloroform
Circular Dichroism
1992
75 Citations (Scopus)

Tryptophan contributions to the unusual circular dichroism of fd bacteriophage

Arnold, G. E., Day, L. A. & Dunker, A., 1992, In : Biochemistry. 31, 34, p. 7948-7956 9 p.

Research output: Contribution to journalArticle

Bacteriophage M13
Bacteriophages
Bromosuccinimide
Circular Dichroism
Tryptophan
15 Citations (Scopus)

Use of conditional probabilities for determining relationships between amino acid sequence and protein secondary structure

Arnold, G. E., Dunker, A., Johns, S. J. & Douthart, R. J., 1992, In : Proteins: Structure, Function and Genetics. 12, 4, p. 382-399 18 p.

Research output: Contribution to journalArticle

Secondary Protein Structure
Amino Acid Sequence
Amino Acids
Proteins
1991
25 Citations (Scopus)

A model for fd phage penetration and assembly

Dunker, A., Ensign, L. D., Arnold, G. E. & Roberts, L. M., Nov 4 1991, In : FEBS Letters. 292, 1-2, p. 271-274 4 p.

Research output: Contribution to journalArticle

Bacteriophage M13
Bacteriophages
Chloroform
Proteins
Capsid Proteins
28 Citations (Scopus)

Proposed molten globule intermediates in fd phage penetration and assembly

Dunker, A., Ensign, L. D., Arnold, G. E. & Roberts, L. M., Nov 4 1991, In : FEBS Letters. 292, 1-2, p. 275-278 4 p.

Research output: Contribution to journalArticle

Bacteriophage M13
Bacteriophages
Molten materials
1990
10 Citations (Scopus)

The effect of donor-acceptor interactions on the mechanical properties of wood

Ma, D., Johns, W. E., Dunker, A. K. & Dunker, A., Jan 1 1990, In : Journal of Adhesion Science and Technology. 4, 1, p. 411-429 19 p.

Research output: Contribution to journalArticle

Wood
mechanical properties
Mechanical properties
acoustic emission
Acoustic emissions
1987
6 Citations (Scopus)

Characterization of hepatic carnitine palmitoyltransferase. Use of bromoacyl derivatives and antibodies

Brady, P. S., Dunker, A. & Brady, L. J., 1987, In : Biochemical Journal. 241, 3, p. 751-757 7 p.

Research output: Contribution to journalArticle

Carnitine O-Palmitoyltransferase
Coenzyme A
Derivatives
Antibodies
Liver
18 Citations (Scopus)

Comparison of lipid/gramicidin dispersions and cocrystals by Raman scattering

Short, K. W., Wallace, B. A., Myers, R. A., Fodor, S. P. A. & Dunker, A., 1987, In : Biochemistry. 26, 2, p. 557-562 6 p.

Research output: Contribution to journalArticle

Gramicidin
Raman Spectrum Analysis
Dispersions
Raman scattering
Lipids
66 Citations (Scopus)

Interaction of synthetic proanthocyanidin dimer and trimer with bovine serum albumin and purified bean globulin fraction G-1

Artz, W. E., Bishop, P. D., Dunker, A., Schanus, E. G. & Swanson, B. G., 1987, In : Journal of Agricultural and Food Chemistry. 35, 3, p. 417-421 5 p.

Research output: Contribution to journalArticle

Globulins
bovine serum albumin
Bovine Serum Albumin
proanthocyanidins
globulins
6 Citations (Scopus)

Limited nucleosome migration can completely randomize DNA repair patches in intact human cells

Arnold, G. E., Dunker, A. & Smerdon, M. J., Jul 20 1987, In : Journal of Molecular Biology. 196, 2, p. 433-436 4 p.

Research output: Contribution to journalArticle

Nucleosomes
DNA Repair
DNA
Ultraviolet Rays
Random Allocation
1 Citation (Scopus)

Trypsin-induced calcium efflux from sarcoplasmic reticulum: Evidence for the involvement of the (Ca2++Mg2+)-ATPase

Huang, J. L., Topping, T. B., He, Z., Folsom, B. & Dunker, A., Dec 1987, In : Journal of Membrane Biology. 100, 1, p. 193-205 13 p.

Research output: Contribution to journalArticle

Ca(2+) Mg(2+)-ATPase
Sarcoplasmic Reticulum
Trypsin
Digestion
Adenosine Triphosphatases
1986
26 Citations (Scopus)

Slightly Bizarre Protein Chemistry: Urea-Formaldehyde Resin from a Biochemical Perspective

Dunker, A., John, W. E., Rammon, R., Farmer, B. & Johns, S. J., 1986, In : The Journal of Adhesion. 19, 2, p. 153-176 24 p.

Research output: Contribution to journalArticle

Urea formaldehyde resins
formaldehyde
ureas
Formaldehyde
Urea
51 Citations (Scopus)

The Chemical Structure of UF Resins

Rammon, R. M., Johns, W. E., Magnuson, J. & Dunker, A., 1986, In : The Journal of Adhesion. 19, 2, p. 115-135 21 p.

Research output: Contribution to journalArticle

Urea formaldehyde resins
formaldehyde
ureas
resins
Resins
1984
21 Citations (Scopus)

Raman spectroscopy and deuterium exchange of the filamentous phage fd

Williams, R. W., Dunker, A. & Peticolas, W. L., Dec 7 1984, In : Biochimica et Biophysica Acta (BBA)/Protein Structure and Molecular. 791, 2, p. 131-144 14 p.

Research output: Contribution to journalArticle

Bacteriophage M13
Bacteriophages
Raman Spectrum Analysis
Deuterium
Raman spectroscopy
1983
2 Citations (Scopus)

Evidence that trypsin digestion exposes a channel in the sarcoplasmic reticulum membrane

Toogood, K. C., Folsom, B., Topping, T., McCutchan, H., Dolejsi, M. J., Johns, S., Stuart, G. & Dunker, A., 1983, In : Molecular Membrane Biology. 5, 1, p. 49-75 27 p.

Research output: Contribution to journalArticle

Sarcoplasmic Reticulum
Trypsin
Digestion
Membranes
Ions