Alan Breier

  • 24150 Citations
  • 84 h-Index
1981 …2020

Research output per year

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Publications

2020

Effects of fingolimod, a sphingosine-1-phosphate (S1P) receptor agonist, on white matter microstructure, cognition and symptoms in schizophrenia

Francis, M. M., Hummer, T. A., Liffick, E., Vohs, J. L., Mehdiyoun, N. F., Visco, A. C., Yang, Z., Kovacs, R. J., Zhang, Y. & Breier, A., 2020, (Accepted/In press) In : Brain Imaging and Behavior.

Research output: Contribution to journalArticle

Functional network connectivity in early-stage schizophrenia

Hummer, T. A., Yung, M. G., Goñi, J., Conroy, S. K., Francis, M. M., Mehdiyoun, N. F. & Breier, A., Apr 2020, In : Schizophrenia Research. 218, p. 107-115 9 p.

Research output: Contribution to journalArticle

Relationship of Metacognition and Insight to Neural Synchronization and Cognitive Function in Early Phase Psychosis

Leonhardt, B. L., Vohs, J. L., Bartolomeo, L. A., Visco, A., Hetrick, W. P., Bolbecker, A. R., Breier, A., Lysaker, P. H. & O’Donnell, B. F., Jul 1 2020, In : Clinical EEG and Neuroscience. 51, 4, p. 259-266 8 p.

Research output: Contribution to journalArticle

1 Scopus citations
2019

Cognitive effects of bilateral high frequency repetitive transcranial magnetic stimulation in early phase psychosis: a pilot study

Francis, M. M., Hummer, T. A., Vohs, J. L., Yung, M. G., Visco, A. C., Mehdiyoun, N. F., Kulig, T. C., Um, M., Yang, Z., Motamed, M., Liffick, E., Zhang, Y. & Breier, A., Jun 15 2019, In : Brain Imaging and Behavior. 13, 3, p. 852-861 10 p.

Research output: Contribution to journalArticle

7 Scopus citations

Herpes simplex virus 1 infection and valacyclovir treatment in schizophrenia: Results from the VISTA study

Breier, A., Buchanan, R. W., D'Souza, D., Nuechterlein, K., Marder, S., Dunn, W., Preskorn, S., Macaluso, M., Wurfel, B., Maguire, G., Kakar, R., Highum, D., Hoffmeyer, D., Coskinas, E., Litman, R., Vohs, J. L., Radnovich, A., Francis, M. M., Metzler, E., Visco, A. & 5 others, Mehdiyoun, N., Yang, Z., Zhang, Y., Yolken, R. H. & Dickerson, F. B., Apr 2019, In : Schizophrenia Research. 206, p. 291-299 9 p.

Research output: Contribution to journalArticle

5 Scopus citations

Internalized stigma in adults with early phase versus prolonged psychosis

Firmin, R. L., Lysaker, P. H., Luther, L., Yanos, P. T., Leonhardt, B., Breier, A. & Vohs, J. L., Aug 2019, In : Early Intervention in Psychiatry. 13, 4, p. 745-751 7 p.

Research output: Contribution to journalArticle

7 Scopus citations

Relationship of auditory electrophysiological responses to magnetic resonance spectroscopy metabolites in Early Phase Psychosis

Bartolomeo, L. A., Wright, A. M., Ma, R. E., Hummer, T. A., Francis, M. M., Visco, A. C., Mehdiyoun, N. F., Bolbecker, A. R., Hetrick, W. P., Dydak, U., Barnard, J., O'Donnell, B. F. & Breier, A., Nov 2019, In : International Journal of Psychophysiology. 145, p. 15-22 8 p.

Research output: Contribution to journalArticle

2 Scopus citations
2018

Auditory feature perception and auditory hallucinatory experiences in schizophrenia spectrum disorder

Schnakenberg Martin, A. M., Bartolomeo, L., Howell, J., Hetrick, W. P., Bolbecker, A. R., Breier, A., Kidd, G. & O’Donnell, B. F., Oct 1 2018, In : European Archives of Psychiatry and Clinical Neuroscience. 268, 7, p. 653-661 9 p.

Research output: Contribution to journalArticle

4 Scopus citations

Characterization of white matter abnormalities in early-stage schizophrenia

Hummer, T. A., Francis, M. M., Vohs, J. L., Liffick, E., Mehdiyoun, N. F. & Breier, A., Aug 2018, In : Early Intervention in Psychiatry. 12, 4, p. 660-668 9 p.

Research output: Contribution to journalArticle

7 Scopus citations

Effects of 12-month, double-blind N-acetyl cysteine on symptoms, cognition and brain morphology in early phase schizophrenia spectrum disorders

Breier, A., Liffick, E., Hummer, T. A., Vohs, J. L., Yang, Z., Mehdiyoun, N. F., Visco, A. C., Metzler, E., Zhang, Y. & Francis, M. M., Sep 2018, In : Schizophrenia Research. 199, p. 395-402 8 p.

Research output: Contribution to journalArticle

23 Scopus citations

Metacognitive Reflection and Insight Therapy for Early Psychosis: A preliminary study of a novel integrative psychotherapy

Vohs, J. L., Leonhardt, B. L., James, A. V., Francis, M. M., Breier, A., Mehdiyoun, N., Visco, A. C. & Lysaker, P. H., May 2018, In : Schizophrenia Research. 195, p. 428-433 6 p.

Research output: Contribution to journalArticle

40 Scopus citations
2017

Association of medial prefrontal resting state functional connectivity and metacognitive capacity in early phase psychosis

Francis, M. M., Hummer, T. A., Leonhardt, B. L., Vohs, J. L., Yung, M. G., Mehdiyoun, N. F., Lysaker, P. H. & Breier, A., Apr 30 2017, In : Psychiatry Research - Neuroimaging. 262, p. 8-14 7 p.

Research output: Contribution to journalArticle

7 Scopus citations

Utilization and cost of health care services during the first episode of psychosis

Liffick, E., Mehdiyoun, N. F., Vohs, J. L., Francis, M. M. & Breier, A., Feb 1 2017, In : Psychiatric Services. 68, 2, p. 131-136 6 p.

Research output: Contribution to journalArticle

5 Scopus citations

“Evaluating acquisition time of rfmri in the human connectome project for early psychosis. How much is enough?”

Bouix, S., Swago, S., West, J. D., Pasternak, O., Breier, A. & Shenton, M. E., Jan 1 2017, Connectomics in NeuroImaging - 1st International Workshop, CNI 2017 Held in Conjunction with MICCAI 2017, Proceedings. Bonilha, L., Wu, G., Laurienti, P. & Munsell, B. C. (eds.). Springer Verlag, p. 108-115 8 p. (Lecture Notes in Computer Science (including subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics); vol. 10511 LNCS).

Research output: Chapter in Book/Report/Conference proceedingConference contribution

2 Scopus citations
2016

Affective systems induce formal thought disorder in early-stage psychosis

Minor, K. S., Marggraf, M. P., Davis, B. J., Mehdiyoun, N. F. & Breier, A., May 1 2016, In : Journal of Abnormal Psychology. 125, 4, p. 537-542 6 p.

Research output: Contribution to journalArticle

13 Scopus citations

Functional neuroanatomical correlates of episodic memory impairment in early phase psychosis

Francis, M. M., Hummer, T. A., Vohs, J. L., Yung, M. G., Liffick, E., Mehdiyoun, N. F., Radnovich, A. J., McDonald, B. C., Saykin, A. J. & Breier, A., Mar 1 2016, In : Brain Imaging and Behavior. 10, 1, p. 1-11 11 p.

Research output: Contribution to journalArticle

9 Scopus citations
7 Scopus citations
2015

A Phase II study of a histamine H3 receptor antagonist GSK239512 for cognitive impairment in stable schizophrenia subjects on antipsychotic therapy

Jarskog, L. F., Lowy, M. T., Grove, R. A., Keefe, R. S. E., Horrigan, J. P., Ball, M. P., Breier, A., Buchanan, R. W., Carter, C. S., Csernansky, J. G., Goff, D. C., Green, M. F., Kantrowitz, J. T., Keshavan, M. S., Laurelle, M., Lieberman, J. A., Marder, S. R., Maruff, P., McMahon, R. P., Seidman, L. J. & 1 others, Peykamian, M. A., May 1 2015, In : Schizophrenia Research. 164, 1-3, p. 136-142 7 p.

Research output: Contribution to journalArticle

25 Scopus citations

Intrinsic motivation and amotivation in first episode and prolonged psychosis

Luther, L., Lysaker, P. H., Firmin, R. L., Breier, A. & Vohs, J. L., Dec 1 2015, In : Schizophrenia Research. 169, 1-3, p. 418-422 5 p.

Research output: Contribution to journalArticle

12 Scopus citations

Metacognitive capacity as a predictor of insight in first-episode psychosis

Vohs, J. L., Lysaker, P. H., Liffick, E., Francis, M. M., Leonhardt, B. L., James, A., Buck, K. D., Hamm, J. A., Minor, K. S., Mehdiyoun, N. & Breier, A., May 15 2015, In : Journal of Nervous and Mental Disease. 203, 5, p. 372-378 7 p.

Research output: Contribution to journalArticle

26 Scopus citations
2014

Metacognition, social cognition, and symptoms in patients with first episode and prolonged psychoses

Vohs, J. L., Lysaker, P. H., Francis, M. M., Hamm, J., Buck, K. D., Olesek, K., Outcalt, J., Dimaggio, G., Leonhardt, B., Liffick, E., Mehdiyoun, N. & Breier, A., Mar 2014, In : Schizophrenia Research. 153, 1-3, p. 54-59 6 p.

Research output: Contribution to journalArticle

78 Scopus citations
2013

Disturbed resting state EEG synchronization in bipolar disorder: A graph-theoretic analysis

Kim, D. J., Bolbecker, A. R., Howell, J., Rass, O., Sporns, O., Hetrick, W. P., Breier, A. & O'Donnell, B. F., 2013, In : NeuroImage: Clinical. 2, 1, p. 414-423 10 p.

Research output: Contribution to journalArticle

70 Scopus citations
2012

Auditory steady state response in the schizophrenia, first-degree relatives, and schizotypal personality disorder

Rass, O., Forsyth, J. K., Krishnan, G. P., Hetrick, W. P., Klaunig, M. J., Breier, A., O'Donnell, B. F. & Brenner, C. A., Apr 2012, In : Schizophrenia Research. 136, 1-3, p. 143-149 7 p.

Research output: Contribution to journalArticle

47 Scopus citations

Computer-assisted cognitive remediation for schizophrenia: A randomized single-blind pilot study

Rass, O., Forsyth, J. K., Bolbecker, A. R., Hetrick, W. P., Breier, A., Lysaker, P. H. & O'Donnell, B. F., Aug 1 2012, In : Schizophrenia Research. 139, 1-3, p. 92-98 7 p.

Research output: Contribution to journalArticle

39 Scopus citations

Convergent functional genomics of schizophrenia: From comprehensive understanding to genetic risk prediction

Ayalew, M., Le-Niculescu, H., Levey, D. F., Jain, N., Changala, B., Patel, S. D., Winiger, E., Breier, A., Shekhar, A., Amdur, R., Koller, D., Nurnberger, J. I., Corvin, A., Geyer, M., Tsuang, M. T., Salomon, D., Schork, N. J., Fanous, A. H., O'Donovan, M. C. & Niculescu, A. B., Sep 1 2012, In : Molecular Psychiatry. 17, 9, p. 887-905 19 p.

Research output: Contribution to journalArticle

261 Scopus citations
2011

Anxiety disorders and antipsychotic drugs: A pressing need for more research

Breier, A., Oct 2011, In : American Journal of Psychiatry. 168, 10, p. 1012-1014 3 p.

Research output: Contribution to journalEditorial

4 Scopus citations

Temporal discounting of rewards in patients with bipolar disorder and schizophrenia

Ahn, W. Y., Rass, O., Fridberg, D. J., Bishara, A. J., Forsyth, J. K., Breier, A., Busemeyer, J. R., Hetrick, W. P., Bolbecker, A. R. & O'Donnell, B. F., Nov 2011, In : Journal of Abnormal Psychology. 120, 4, p. 911-921 11 p.

Research output: Contribution to journalArticle

80 Scopus citations
2010

Genetic association study of treatment response with olanzapine/fluoxetine combination or lamotrigine in bipolar I depression

Perlis, R. H., Adams, D. H., Fijal, B., Sutton, V. K., Farmen, M., Breier, A. & Houston, J. P., May 1 2010, In : Journal of Clinical Psychiatry. 71, 5, p. 599-605 7 p.

Research output: Contribution to journalArticle

33 Scopus citations

Pharmacotherapy of first-episode schizophrenia

Liffick, E. & Breier, A., Jun 2010, In : Psychopharm Review. 45, 6, p. 41-48 8 p.

Research output: Contribution to journalArticle

1 Scopus citations
2009

A 28-week, randomized, double-blind study of olanzapine versus aripiprazole in the treatment of schizophrenia

Kane, J. M., Osuntokun, O., Kryzhanovskaya, L. A., Xu, W., Stauffer, V. L., Watson, S. B. & Breier, A., Apr 1 2009, In : Journal of Clinical Psychiatry. 70, 4, p. 572-581 10 p.

Research output: Contribution to journalArticle

50 Scopus citations

Bayesian adaptive non-inferiority with safety assessment: Retrospective case study to highlight potential benefits and limitations of the approach

Spann, M., Lindborg, S., Seaman, J., Baker, R., Dunayevich, E. & Breier, A., Feb 1 2009, In : Journal of Psychiatric Research. 43, 5, p. 561-567 7 p.

Research output: Contribution to journalArticle

3 Scopus citations

Innovative therapeutics for schizophrenia

Breier, A. & Shekhar, A., Mar 2009, In : Psychopharm Review. 44, 3, p. 17-24 8 p.

Research output: Contribution to journalArticle

2008

Dopamine receptor D3 genotype association with greater acute positive symptom remission with olanzapine therapy in predominately caucasian patients with chronic schizophrenia or schizoaffective disorder

Adams, D. H., Close, S., Farmen, M., Downing, A. C. M., Breier, A. & Houston, J. P., Jun 1 2008, In : Human Psychopharmacology. 23, 4, p. 267-274 8 p.

Research output: Contribution to journalArticle

33 Scopus citations

Neuropsychological course in the prodrome and first episode of psychosis: Findings from the PRIME North America Double Blind Treatment Study

Hawkins, K. A., Keefe, R. S. E., Christensen, B. K., Addington, J., Woods, S. W., Callahan, J., Zipursky, R. B., Perkins, D. O., Tohen, M., Breier, A. & McGlashan, T. H., Oct 2008, In : Schizophrenia Research. 105, 1-3, p. 1-9 9 p.

Research output: Contribution to journalArticle

64 Scopus citations

Schizophrenia and Other Psychoses

Patel, J. K., Pinals, D. A., Breier, A. & First, M. B., Aug 8 2008, Psychiatry: Third Edition. John Wiley & Sons, Ltd, Vol. 1. p. 1201-1282 82 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

2 Scopus citations

Commentary: Wayne Fenton's impact on industry

Breier, A., Alphs, L. & Binneman, B., Sep 1 2007, In : Schizophrenia bulletin. 33, 5, p. 1154-1155 2 p.

Research output: Contribution to journalComment/debate

1 Scopus citations

Extracting spurious messages from noise and risk of schizophrenia-spectrum disorders in a prodromal population

Hoffman, R. E., Woods, S. W., Hawkins, K. A., Pittman, B., Tohen, M., Preda, A., Breier, A., Glist, J., Addington, J., Perkins, D. O. & McGlashan, T. H., Oct 1 2007, In : British Journal of Psychiatry. 191, OCT., p. 355-356 2 p.

Research output: Contribution to journalArticle

43 Scopus citations

Metacognition in early phase psychosis: Toward understanding neural substrates

Vohs, J. L., Hummer, T. A., Yung, M. G., Francis, M. M., Lysaker, P. H. & Breier, A., Jun 29 2007, In : International journal of molecular sciences. 16, 7, p. 14640-14654 15 p.

Research output: Contribution to journalArticle

8 Scopus citations

Neuroreceptor gene polymorphisms and olanzapine depressive symptom response in schizophrenia [6]

Houston, J. P., Adams, D. H., Kirkwood, S. C., Farmen, M., Downing, A. M. & Breier, A., Oct 1 2007, In : Journal of Clinical Psychopharmacology. 27, 5, p. 520-523 4 p.

Research output: Contribution to journalLetter

6 Scopus citations

Psychiatric safety of ketamine in psychopharmacology research

Perry, E. B., Cramer, J. A., Cho, H. S., Petrakis, I. L., Karper, L. P., Genovese, A., O'Donnell, E., Krystal, J. H., D'Souza, D. C., Abi-Dargham, A., Abi-Saab, D., Abi-Saab, W., Ammerman, Y. W., Anand, A., Belger, A., Bennett, A., Berman, R. M., Boutros, N., Bowers, M. B., Breier, A. & 43 others, Bremner, J. D., Brush, L., Cappiello, A., Cassello, K., Charney, D. S., Cho, H., Cooney, N. L., Cooper, T. B., Cramer, J., Damon, D., Delaney, R., D'Souza, D. C., Freeman, G. K., Gelernter, J., Gil, R., Grillon, C., Gueorguieva, R., Heninger, G. R., Hu, X. S., Hunsberger, T., Jatlow, P., Karper, L. P., Krystal, J. H., Levine, L., Limoncelli, D., Lipschitz, D. S., Liu, N., MacDougall, L., Madonick, S. H., Morrissey, K., Namenworth, S., Oren, D. A., Perry, E. B., Petrakis, I. L., Seibyl, J. P., Stetson, P., Suckow, R. F., Trevisan, L. A., Vegso, S., Webb, E., White, J. A., Zimmerman, L. & Zuzarte, E., Jun 2007, In : Psychopharmacology. 192, 2, p. 253-260 8 p.

Research output: Contribution to journalArticle

85 Scopus citations
2006

Diabetes mellitus and antipsychotic treatment in the United Kingdom

Carlson, C., Hornbuckle, K., DeLisle, F., Kryzhanovskaya, L., Breier, A. & Cavazzoni, P., Jul 1 2006, In : European Neuropsychopharmacology. 16, 5, p. 366-375 10 p.

Research output: Contribution to journalArticle

32 Scopus citations

One-year double-blind study of the neurocognitive efficacy of olanzapine, risperidone, and haloperidol in schizophrenia

Keefe, R. S. E., Young, C. A., Rock, S. L., Purdon, S. E., Gold, J. M. & Breier, A., Jan 1 2006, In : Schizophrenia Research. 81, 1, p. 1-15 15 p.

Research output: Contribution to journalArticle

126 Scopus citations

Randomized, double-blind trial of olanzapine versus placebo in patients prodromally symptomatic for psychosis

McGlashan, T. H., Zipursky, R. B., Perkins, D., Addington, J., Miller, T., Woods, S. W., Hawkins, K. A., Hoffman, R. E., Preda, A., Epstein, I., Addington, D., Lindborg, S., Trzaskoma, Q., Tohen, M. & Breier, A., May 2006, In : American Journal of Psychiatry. 163, 5, p. 790-799 10 p.

Research output: Contribution to journalArticle

439 Scopus citations
2005

Amantadine for weight gain associated with olanzapine treatment

Deberdt, W., Winokur, A., Cavazzoni, P. A., Trzaskoma, Q. N., Carlson, C. D., Bymaster, F. P., Wiener, K., Floris, M. & Breier, A., Jan 1 2005, In : European Neuropsychopharmacology. 15, 1, p. 13-21 9 p.

Research output: Contribution to journalArticle

62 Scopus citations

Comparison of olanzapine and risperidone in the treatment of psychosis and associated behavioral disturbances in patients with dementia

Deberdt, W. G., Dysken, M. W., Rappaport, S. A., Feldman, P. D., Young, C. A., Hay, D. P., Lehman, D. L., Dossenbach, M., Degenhardt, E. K. & Breier, A., Aug 2005, In : American Journal of Geriatric Psychiatry. 13, 8, p. 722-730 9 p.

Research output: Contribution to journalArticle

97 Scopus citations

Developing drugs for cognitive impairment in schizophrenia

Breier, A., Oct 1 2005, In : Schizophrenia bulletin. 31, 4, p. 816-822 7 p.

Research output: Contribution to journalArticle

24 Scopus citations

Drug-induced psychosis in Parkinson disease: Phenomenology and correlations among psychosis rating instruments

Chou, K. L., Messing, S., Oakes, D., Feldman, P. D., Breier, A. & Friedman, J. H., Sep 1 2005, In : Clinical neuropharmacology. 28, 5, p. 215-219 5 p.

Research output: Contribution to journalArticle

64 Scopus citations

Effectiveness of antipsychotic treatment for schizophrenia: 6-Month results of the Pan-European Schizophrenia Outpatient Health Outcomes (SOHO) study

Haro, J. M., Edgell, E. T., Novick, D., Alonso, J., Kennedy, L., Jones, P. B., Ratcliffe, M. & Breier, A., Mar 2005, In : Acta Psychiatrica Scandinavica. 111, 3, p. 220-231 12 p.

Research output: Contribution to journalArticle

84 Scopus citations

Olanzapine versus ziprasidone: Results of a 23-week double-blind study in patients with schizophrenia

Breier, A., Berg, P. H., Thakore, J. H., Naber, D., Gattaz, W. F., Cavazzoni, P., Walker, D. J., Roychowdhury, S. M. & Kane, J. M., Oct 1 2005, In : American Journal of Psychiatry. 162, 10, p. 1879-1887 9 p.

Research output: Contribution to journalArticle

115 Scopus citations