Amelia Linnemann

  • 759 Citations
  • 14 h-Index
20072019
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Publications 2007 2019

  • 759 Citations
  • 14 h-Index
  • 17 Article
  • 5 Review article
2007
18 Citations (Scopus)

Genomewide identification of nuclear matrix attachment regions: An analysis of methods

Linnemann, A. K., Platts, A. E., Doggett, N., Gluch, A., Bode, J. & Krawetz, S. A., Jun 1 2007, In : Biochemical Society transactions. 35, 3, p. 612-617 6 p.

Research output: Contribution to journalArticle

Matrix Attachment Regions
Nuclear Matrix
Technology
Chromosomes, Human, Pair 16
Cosmids
2008
16 Citations (Scopus)

Real-time PCR quantification using a variable reaction efficiency model

Platts, A. E., Johnson, G. D., Linnemann, A. K. & Krawetz, S. A., Sep 15 2008, In : Analytical biochemistry. 380, 2, p. 315-322 8 p.

Research output: Contribution to journalArticle

Polymerase chain reaction
Noise
Real-Time Polymerase Chain Reaction
Sequence Analysis
Gene Expression
2009
47 Citations (Scopus)

Differential nuclear scaffold/matrix attachment marks expressed genes

Linnemann, A. K., Platts, A. E. & Krawetz, S. A., Feb 4 2009, In : Human molecular genetics. 18, 4, p. 645-654 10 p.

Research output: Contribution to journalArticle

Matrix Attachment Regions
Nuclear Matrix
Genes
Genome
Chromosomes, Human, Pair 18
253 Citations (Scopus)

Discovering Hematopoietic Mechanisms through Genome-wide Analysis of GATA Factor Chromatin Occupancy

Fujiwara, T., O'Geen, H., Keles, S., Blahnik, K., Linnemann, A. K., Kang, Y. A., Choi, K., Farnham, P. J. & Bresnick, E. H., Nov 25 2009, In : Molecular Cell. 36, 4, p. 667-681 15 p.

Research output: Contribution to journalArticle

GATA Transcription Factors
Chromatin
Hematopoiesis
Genome
Co-Repressor Proteins
20 Citations (Scopus)

Maintenance of a functional higher order chromatin structure: The role of the nuclear matrix in normal and disease states

Linnemann, A. K. & Krawetz, S. A., Dec 1 2009, In : Gene Therapy and Molecular Biology. 13, 1, p. 231-243 13 p.

Research output: Contribution to journalReview article

Matrix Attachment Regions
Nuclear Matrix
Chromatin
DNA Packaging
Cell Nucleus
17 Citations (Scopus)

Silencing by nuclear matrix attachment distinguishes cell-type specificity: Association with increased proliferation capacity

Linnemann, A. K. & Krawetz, S. A., Jun 8 2009, In : Nucleic acids research. 37, 9, p. 2779-2788 10 p.

Research output: Contribution to journalArticle

Nuclear Matrix
Matrix Attachment Regions
Adventitia
HeLa Cells
Fibroblasts
2010
5 Citations (Scopus)

Nuclear Matrix Association: Switching to the Invasive Cytotrophoblast

Drennan, K. J., Linnemann, A. K., Platts, A. E., Heng, H. H., Armant, D. R. & Krawetz, S. A., May 1 2010, In : Placenta. 31, 5, p. 365-372 8 p.

Research output: Contribution to journalArticle

Nuclear Matrix
Trophoblasts
Transcriptome
Phenotype
Chromosomes, Human, Pair 18
2011
55 Citations (Scopus)

Genetic framework for GATA factor function in vascular biology

Linnemann, A. K., O'Geen, H., Keles, S., Farnham, P. J. & Bresnick, E. H., Aug 16 2011, In : Proceedings of the National Academy of Sciences of the United States of America. 108, 33, p. 13641-13646 6 p.

Research output: Contribution to journalArticle

GATA Transcription Factors
Transcription Factor AP-1
Blood Vessels
Chromatin
Endothelial Cells
107 Citations (Scopus)

The sperm nucleus: Chromatin, RNA, and the nuclear matrix

Johnson, G. D., Lalancette, C., Linnemann, A. K., Leduc, F., Boissonneault, G. & Krawetz, S. A., Jan 2011, In : Reproduction. 141, 1, p. 21-36 16 p.

Research output: Contribution to journalReview article

Nuclear Matrix
Chromatin
Spermatozoa
Genome
RNA
2012
75 Citations (Scopus)

Autophagy driven by a master regulator of hematopoiesis

Kang, Y. A., Sanalkumar, R., O'geen, H., Linnemann, A. K., Chang, C. J., Bouhassira, E. E., Farnham, P. J., Keles, S. & Bresnick, E. H., Jan 1 2012, In : Molecular and cellular biology. 32, 1, p. 226-239 14 p.

Research output: Contribution to journalArticle

Autophagy
Hematopoiesis
Light
Forkhead Transcription Factors
Microtubule-Associated Proteins
2013
15 Citations (Scopus)

Tcf19 is a novel islet factor necessary for proliferation and survival in the INS-1 β-cell line

Krautkramer, K. A., Linnemann, A. K., Fontaine, D. A., Whillock, A. L., Harris, T. W., Schleis, G. J., Truchan, N. A., Marty-Santos, L., Lavine, J. A., Cleaver, O., Kimple, M. E. & Davis, D. B., Sep 17 2013, In : American Journal of Physiology - Endocrinology and Metabolism. 305, 5, p. E600-E610

Research output: Contribution to journalArticle

Cell Line
Survival
Insulinoma
Apoptosis
Calreticulin
2014
20 Citations (Scopus)

Inhibitory G proteins and their receptors: Emerging therapeutic targets for obesity and diabetes

Kimple, M. E., Neuman, J. C., Linnemann, A. K. & Casey, P. J., Jun 2014, In : Experimental and Molecular Medicine. 46, 6, e102.

Research output: Contribution to journalReview article

Medical problems
GTP-Binding Proteins
Type 2 Diabetes Mellitus
Obesity
Insulin
39 Citations (Scopus)

Pancreatic β-cell proliferation in obesity

Linnemann, A. K., Baan, M. & Davis, D. B., Jan 1 2014, In : Advances in Nutrition. 5, 3, p. 278-288 11 p.

Research output: Contribution to journalReview article

cell proliferation
obesity
Obesity
Cell Proliferation
insulin
2015
21 Citations (Scopus)

Glucagon-like peptide-1 regulates cholecystokinin production in β-cells to protect from apoptosis

Linnemann, A. K., Neuman, J. C., Battiola, T. J., Wisinski, J. A., Kimple, M. E. & Davis, D. B., Jul 1 2015, In : Molecular Endocrinology. 29, 7, p. 978-987 10 p.

Research output: Contribution to journalArticle

Glucagon-Like Peptide 1
Cholecystokinin
Apoptosis
Cyclic AMP Response Element-Binding Protein
Obesity
2016
4 Citations (Scopus)
Glucagon-Like Peptide 1
Cholecystokinin
Islets of Langerhans
Incretins
Obesity
2017
10 Citations (Scopus)

Inhibition of 12/15-Lipoxygenase Protects Against β-Cell Oxidative Stress and Glycemic Deterioration in Mouse Models of Type 1 Diabetes

Hernandez-Perez, M., Chopra, G., Fine, J., Conteh, A. M., Anderson, R. M., Linnemann, A., Benjamin, C., Nelson, J. B., Benninger, K. S., Nadler, J. L., Maloney, D. J., Tersey, S. A. & Mirmira, R., Nov 1 2017, In : Diabetes. 66, 11, p. 2875-2887 13 p.

Research output: Contribution to journalArticle

Type 1 Diabetes Mellitus
Oxidative Stress
Macrophages
Islets of Langerhans
Inbred NOD Mouse
19 Citations (Scopus)

Interleukin 6 protects pancreatic b cells from apoptosis by stimulation of autophagy

Linnemann, A., Blumer, J., Marasco, M. R., Battiola, T. J., Umhoefer, H. M., Han, J. Y., Lamming, D. W. & Davis, D. B., Sep 1 2017, In : FASEB Journal. 31, 9, p. 4140-4152 13 p.

Research output: Contribution to journalArticle

Autophagy
Interleukin-6
Apoptosis
STAT3 Transcription Factor
Glucagon-Like Peptide 1
2018
1 Citation (Scopus)

An In Vivo Zebrafish Model for Interrogating ROS-Mediated Pancreatic β-Cell Injury, Response, and Prevention

Kulkarni, A. A., Conteh, A. M., Sorrell, C. A., Mirmira, A., Tersey, S. A., Mirmira, R., Linnemann, A. & Anderson, R. M., Jan 1 2018, In : Oxidative Medicine and Cellular Longevity. 2018, 1 p.

Research output: Contribution to journalArticle

Zebrafish
Reactive Oxygen Species
Wounds and Injuries
Metronidazole
Pathology
7 Citations (Scopus)

B-Cell autophagy in diabetes pathogenesis

Marasco, M. R. & Linnemann, A., May 1 2018, In : Endocrinology. 159, 5, p. 2127-2141 15 p.

Research output: Contribution to journalReview article

Autophagy
B-Lymphocytes
Type 1 Diabetes Mellitus
Type 2 Diabetes Mellitus
Insulin
8 Citations (Scopus)

Interleukin-6 Reduces β-Cell Oxidative Stress by Linking Autophagy With the Antioxidant Response

Mirmira, R., Linnemann, A., Reissaus, C. A., Cupit, J. E., Appleman, E. M., Mirmira, R. G. & Linnemann, A. K., Aug 1 2018, In : Diabetes. 67, 8, p. 1576-1588 13 p.

Research output: Contribution to journalArticle

Autophagy
Interleukin-6
Oxidative Stress
Antioxidants
Reactive Oxygen Species
2019
1 Citation (Scopus)

A Versatile, Portable Intravital Microscopy Platform for Studying Beta-cell Biology In Vivo

Reissaus, C. A., Piñeros, A. R., Twigg, A. N., Orr, K. S., Conteh, A. M., Martinez, M. M., Kamocka, M., Day, R., Tersey, S. A., Mirmira, R., Dunn, K. & Linnemann, A., Dec 1 2019, In : Scientific Reports. 9, 1, 8449.

Research output: Contribution to journalArticle

Open Access
Biosensing Techniques
Cell Biology
Cell Physiological Phenomena
Aptitude
Calcium Signaling
1 Citation (Scopus)

Platelet-type 12-lipoxygenase deletion provokes a compensatory 12/15-lipoxygenase increase that exacerbates oxidative stress in mouse islet β cells

Conteh, A. M., Reissaus, C. A., Hernandez-Perez, M., Nakshatri, S., Anderson, R. M., Mirmira, R., Tersey, S. A. & Linnemann, A., Jan 1 2019, In : Journal of Biological Chemistry. 294, 16, p. 6612-6620 9 p.

Research output: Contribution to journalArticle

Arachidonate 12-Lipoxygenase
Oxidative stress
Platelets
Islets of Langerhans
Oxidative Stress