Ann Hake

  • Associate Professor of Clinical Neurology, Neurology
  • 5709 Citations
  • 27 h-Index
19982020

Research output per year

If you made any changes in Pure these will be visible here soon.

Publications

α2 Macroglobulin and the risk of Alzheimer's disease

Dodel, R. C., Du, Y., Bales, K. R., Gao, F., Eastwood, B., Glazier, B., Zimmer, R., Cordell, B., Hake, A., Evans, R., Gallagher-Thompson, D., Thompson, L. W., Tinklenberg, J. R., Pfefferbaum, A., Sullivan, E. V., Yesavage, J., Altstiel, L., Gasser, T., Farlow, M. R., Murphy, G. M. & 1 others, Paul, S. M., Jan 25 2000, In : Neurology. 54, 2, p. 438-442 5 p.

Research output: Contribution to journalArticle

65 Scopus citations

Weight loss and incident dementia in elderly Yoruba Nigerians: A 10-year follow-up study

Ogunniyi, A., Gao, S., Unverzagt, F. W., Baiyewu, O., Gureje, O., Nguyen, J. T., Smith-Gamble, V., Murrell, J. R., Hake, A. M., Hall, K. S. & Hendrie, H. C., Apr 1 2011, In : International Psychogeriatrics. 23, 3, p. 387-394 8 p.

Research output: Contribution to journalArticle

17 Scopus citations

Visual function in Hungtington's disease patients and presymptomatic gene carriers

O'Donnell, B. F., Wilt, M. A., Hake, A. M., Stout, J. C., Kirkwood, S. C. & Foroud, T., Sep 1 2003, In : Movement Disorders. 18, 9, p. 1027-1034 8 p.

Research output: Contribution to journalArticle

9 Scopus citations

Use of cholinesterase inhibitors for treatment of Alzheimer disease

Hake, A. M., Jul 1 2001, In : Cleveland Clinic Journal of Medicine. 68, 7, p. 608-616 9 p.

Research output: Contribution to journalArticle

18 Scopus citations

Use of anticholinergics and the risk of cognitive impairment in an African American population

Campbell, N. L., Boustani, M. A., Lane, K. A., Gao, S., Hendrie, H., Khan, B. A., Murrell, J. R., Unverzagt, F. W., Hake, A., Smith-Gamble, V. & Hall, K., Jul 13 2010, In : Neurology. 75, 2, p. 152-159 8 p.

Research output: Contribution to journalArticle

95 Scopus citations

Uncovering the heterogeneity and temporal complexity of neurodegenerative diseases with Subtype and Stage Inference

The Genetic FTD Initiative (GENFI) & The Alzheimer’s Disease Neuroimaging Initiative (ADNI), Dec 1 2018, In : Nature communications. 9, 1, 4273.

Research output: Contribution to journalArticle

33 Scopus citations

Type 2 diabetes mellitus, brain atrophy, and cognitive decline

Moran, C., Beare, R., Wang, W., Callisaya, M., Srikanth, V., Weiner, M., Aisen, P., Petersen, R., Jack, C. R., Jagust, W., Trojanowki, J. Q., Toga, A. W., Beckett, L., Green, R. C., Saykin, A. J., Morris, J., Liu, E., Montine, T., Gamst, A., Thomas, R. G. & 234 others, Donohue, M., Walter, S., Gessert, D., Sather, T., Harvey, D., Kornak, J., Dale, A., Bernstein, M., Felmlee, J., Fox, N., Thompson, P., Schuff, N., Alexander, G., Decarli, C., Bandy, D., Koeppe, R. A., Foster, N., Reiman, E. M., Chen, K., Mathis, C., Cairns, N. J., Taylor-Reinwald, L., Trojanowki, J. Q., Shaw, L., Lee, V. M. Y., Korecka, M., Crawford, K., Neu, S., Foroud, T. M., Potkin, S., Shen, L., Kachaturian, Z., Frank, R., Snyder, P. J., Molchan, S., Kaye, J., Quinn, J., Lind, B., Dolen, S., Schneider, L. S., Pawluczyk, S., Spann, B. M., Brewer, J., Vanderswag, H., Heidebrink, J. L., Lord, J. L., Johnson, K., Doody, R. S., Villanueva-Meyer, J., Chowdhury, M., Stern, Y., Honig, L. S., Bell, K. L., Morris, J. C., Ances, B., Carroll, M., Leon, S., Mintun, M. A., Schneider, S., Marson, D., Griffith, R., Clark, D., Grossman, H., Mitsis, E., Romirowsky, A., Detoledo-Morrell, L., Shah, R. C., Duara, R., Varon, D., Roberts, P., Albert, M., Onyike, C., Kielb, S., Rusinek, H., De Leon, M. J., Glodzik, L., De Santi, S., Doraiswamy, P. M., Petrella, J. R., Coleman, R. E., Arnold, S. E., Karlawish, J. H., Wolk, D., Smith, C. D., Jicha, G., Hardy, P., Lopez, O. L., Oakley, M., Simpson, D. M., Porsteinsson, A. P., Goldstein, B. S., Martin, K., Makino, K. M., Ismail, M. S., Brand, C., Mulnard, R. A., Thai, G., McAdams-Ortiz, C., Womack, K., Mathews, D., Quiceno, M., Diaz-Arrastia, R., King, R., Weiner, M., Martin-Cook, K., Devous, M., Levey, A. I., Lah, J. J., Cellar, J. S., Burns, J. M., Anderson, H. S., Swerdlow, R. H., Apostolova, L., Lu, P. H., Bartzokis, G., Silverman, D. H. S., Graff-Radford, N. R., Parfitt, F., Johnson, H., Farlow, M. R., Hake, A. M., Matthews, B. R., Herring, S., Van Dyck, C. H., Carson, R. E., Macavoy, M. G., Chertkow, H., Bergman, H., Hosein, C., Black, S., Stefanovic, B., Caldwell, C., Robin Hsiung, G. Y., Feldman, H., Mudge, B., Assaly, M., Kertesz, A., Rogers, J., Trost, D., Bernick, C., Munic, D., Kerwin, D., Mesulam, M. M., Lipowski, K., Wu, C. K., Johnson, N., Sadowsky, C., Martinez, W., Villena, T., Turner, R. S., Johnson, K., Reynolds, B., Sperling, R. A., Johnson, K. A., Marshall, G., Frey, M., Yesavage, J., Taylor, J. L., Lane, B., Rosen, A., Tinklenberg, J., Sabbagh, M., Belden, C., Jacobson, S., Kowall, N., Killiany, R., Budson, A. E., Norbash, A., Johnson, P. L., Obisesan, T. O., Wolday, S., Bwayo, S. K., Lerner, A., Hudson, L., Ogrocki, P., Fletcher, E., Carmichael, O., Olichney, J., Kittur, S., Borrie, M., Bartha, D. R., Johnson, S., Asthana, S., Carlsson, C. M., Potkin, S. G., Preda, A., Nguyen, D., Tariot, P., Fleisher, A., Reeder, S., Bates, V., Capote, H., Rainka, M., Scharre, D. W., Kataki, M., Zimmerman, E. A., Celmins, D., Brown, A. D., Pearlson, G. D., Blank, K., Anderson, K., Santulli, R. B., Schwartz, E. S., Sink, K. M., Williamson, J. D., Garg, P., Watkins, F., Ott, B. R., Querfurth, H., Tremont, G., Salloway, S., Malloy, P., Correia, S., Rosen, H. J., Miller, B. L., Mintzer, J., Longmire, C. F., Spicer, K., Finger, E., Rachinsky, I., Drost, D., Pomara, N., Hernando, R., Sarrael, A., Schultz, S. K., Boles Ponto, L. L., Shim, H., Smith, K. E., Relkin, N., Chaing, G., Raudin, L., Smith, A., Fargher, K. & Raj, B. A., Feb 19 2019, In : Neurology. 92, 8, p. E823-E830

Research output: Contribution to journalArticle

11 Scopus citations

Trial of solanezumab for mild dementia due to Alzheimer's disease

Honig, L. S., Vellas, B., Woodward, M., Boada, M., Bullock, R., Borrie, M., Hager, K., Andreasen, N., Scarpini, E., Liu-Seifert, H., Case, M., Dean, R. A., Hake, A., Sundell, K., Hoffmann, V. P., Carlson, C., Khanna, R., Mintun, M., DeMattos, R., Selzler, K. J. & 1 others, Siemers, E., Jan 25 2018, In : New England Journal of Medicine. 378, 4, p. 321-330 10 p.

Research output: Contribution to journalArticle

268 Scopus citations

The use of memantine in dementia with Lewy bodies

Sabbagh, M. N., Hake, A. M., Ahmed, S. & Farlow, M. R., Jan 1 2005, In : Journal of Alzheimer's Disease. 7, 4, p. 285-289 5 p.

Research output: Contribution to journalReview article

50 Scopus citations

The treatment of Alzheimer's disease: The approach from a clinical specialist in the Trenches

Hake, A. M., Aug 1 2002, In : Seminars in Neurology. 22, 1, p. 71-74 4 p.

Research output: Contribution to journalReview article

7 Scopus citations

The relationship between cholesterol and cognitive function is homocysteine-dependent

Cheng, Y., Jin, Y., Unverzagt, F. W., Su, L., Yang, L., Ma, F., Hake, A. M., Kettler, C., Chen, C., Liu, J., Bian, J., Li, P., Murrell, J. R., Hendrie, H. C. & Gao, S., 2014, In : Clinical interventions in aging. 9, p. 1823-1829 7 p.

Research output: Contribution to journalArticle

17 Scopus citations

The current state of acute treatment for migraine in adults in the United States

Cooper, W., Doty, E. G., Hochstetler, H., Hake, A. & Martin, V., 2020, (Accepted/In press) In : Postgraduate Medicine.

Research output: Contribution to journalReview article

Open Access

The BIN1 rs744373 SNP is associated with increased tau-PET levels and impaired memory

The Alzheimer’s Disease Neuroimaging Initiative (ADNI), Dec 1 2019, In : Nature communications. 10, 1, 1766.

Research output: Contribution to journalArticle

Open Access
8 Scopus citations

The association between selenium and lipid levels: A longitudinal study in rural elderly Chinese

Chen, C., Jin, Y., Unverzagt, F. W., Cheng, Y., Hake, A. M., Liang, C., Ma, F., Su, L., Liu, J., Bian, J., Li, P. & Gao, S., Jan 1 2015, In : Archives of Gerontology and Geriatrics. 60, 1, p. 147-152 6 p.

Research output: Contribution to journalArticle

10 Scopus citations

Targeting Alzheimer's Disease in the Preclinical Stage

McDade, E., Hake, A. M., Bain, L. J. & Carrillo, M., 2019, (Accepted/In press) In : Alzheimer's and Dementia.

Research output: Contribution to journalComment/debate

Statin use, incident dementia and Alzheimer disease in elderly African Americans

Hendrie, H. C., Hake, A., Lane, K., Purnell, C., Unverzagt, F., Smith-Gamble, V., Murrell, J., Ogunniyi, A., Baiyewu, O., Callahan, C., Saykin, A., Taylor, S., Hall, K. & Gao, S., Jun 1 2015, In : Ethnicity and Disease. 25, 3, p. 345-354 10 p.

Research output: Contribution to journalArticle

Open Access
24 Scopus citations

Selenium level and Dyslipidemia in rural elderly Chinese

Su, L., Gao, S., Unverzagt, F., Cheng, Y., Hake, A., Xin, P., Chen, C., Liu, J., Ma, F., Bian, J., Li, P. & Jin, Y., Sep 18 2015, In : PLoS One. 10, 9, e0136706.

Research output: Contribution to journalArticle

12 Scopus citations

Response of patients with Alzheimer disease to rivastigmine treatment is predicted by the rate of disease progression

Farlow, M. R., Hake, A., Messina, J., Hartman, R., Veach, J. & Anand, R., 2001, In : Archives of Neurology. 58, 3, p. 417-422 6 p.

Research output: Contribution to journalArticle

Open Access
84 Scopus citations

Representativeness of European clinical trial populations in mild Alzheimer's disease dementia: A comparison of 18-month outcomes with real-world data from the GERAS observational study

Reed, C., Belger, M., Dell'Agnello, G., Kahle-Wrobleski, K., Sethuraman, G., Hake, A., Raskin, J. & Henley, D., Apr 3 2018, In : Alzheimer's Research and Therapy. 10, 1, 36.

Research output: Contribution to journalArticle

1 Scopus citations

Regional Amyloid-β Load and White Matter Abnormalities Contribute to Hypometabolism in Alzheimer’s Dementia

for the Alzheimer’s Disease Neuroimaging Initiative, Jul 1 2019, In : Molecular Neurobiology. 56, 7, p. 4916-4924 9 p.

Research output: Contribution to journalArticle

4 Scopus citations

Presymptomatic genetic testing with an APP mutation in Early-onset Alzheimer disease: A descriptive study of sibship dynamics

Quaid, K. A., Murrell, J. R., Hake, A. M., Farlow, M. R. & Ghetti, B., 2000, In : Journal of Genetic Counseling. 9, 4, p. 327-341 15 p.

Research output: Contribution to journalReview article

7 Scopus citations

Predicting Short-term MCI-to-AD Progression Using Imaging, CSF, Genetic Factors, Cognitive Resilience, and Demographics

for the Alzheimer’s Disease Neuroimaging Initiative, Dec 1 2019, In : Scientific reports. 9, 1, 2235.

Research output: Contribution to journalArticle

Open Access
6 Scopus citations

Predicting Alzheimer’s disease progression using multi-modal deep learning approach

for Alzheimer’s Disease Neuroimaging Initiative, Dec 1 2019, In : Scientific reports. 9, 1, 1952.

Research output: Contribution to journalArticle

Open Access
30 Scopus citations

Pharmacokinetics and Pharmacodynamics of LY2599666, a PEG-Linked Antigen Binding Fragment that Targets Soluble Monomer Amyloid-β

Li, L., Zhen, E. Y., Decker, R. L., Willis, B. A., Waters, D., Liu, P., Hake, A. M., Demattos, R. B. & Ayan-Oshodi, M., Jan 1 2019, In : Journal of Alzheimer's Disease. 68, 1, p. 137-144 8 p.

Research output: Contribution to journalArticle

1 Scopus citations

Pattern Discovery in Brain Imaging Genetics via SCCA Modeling with a Generic Non-convex Penalty

Du, L., Liu, K., Yao, X., Yan, J., Risacher, S. L., Han, J., Guo, L., Saykin, A. J., Shen, L., Weiner, M. W., Aisen, P., Petersen, R., Jack, C. R., Jagust, W., Trojanowki, J. Q., Toga, A. W., Beckett, L., Green, R. C., Morris, J., Shaw, L. M. & 293 others, Khachaturian, Z., Sorensen, G., Carrillo, M., Kuller, L., Raichle, M., Paul, S., Davies, P., Fillit, H., Hefti, F., Holtzman, D., Mesulam, M. M., Potter, W., Snyder, P., Schwartz, A., Montine, T., Thomas, R. G., Donohue, M., Walter, S., Gessert, D., Sather, T., Jiminez, G., Balasubramanian, A. B., Mason, J., Sim, I., Harvey, D., Bernstein, M., Fox, N., Thompson, P., Schuff, N., Decarli, C., Borowski, B., Gunter, J., Senjem, M., Vemuri, P., Jones, D., Kantarci, K., Ward, C., Koeppe, R. A., Foster, N., Reiman, E. M., Chen, K., Mathis, C., Landau, S., Cairns, N. J., Franklin, E., Taylor-Reinwald, L., Lee, V., Korecka, M., Figurski, M., Crawford, K., Neu, S., Foroud, T. M., Potkin, S., Faber, K., Kim, S., Nho, K., Thal, L., Buckholtz, N., Albert, M., Frank, R., Hsiao, J., Kaye, J., Quinn, J., Silbert, L., Lind, B., Carter, R., Dolen, S., Schneider, L. S., Pawluczyk, S., Beccera, M., Teodoro, L., Spann, B. M., Brewer, J., Vanderswag, H., Fleisher, A., Heidebrink, J. L., Lord, J. L., Mason, S. S., Albers, C. S., Knopman, D., Johnson, K., Doody, R. S., Villanueva-Meyer, J., Pavlik, V., Shibley, V., Chowdhury, M., Rountree, S., Dang, M., Stern, Y., Honig, L. S., Bell, K. L., Ances, B., Carroll, M., Creech, M. L., Franklin, E., Mintun, M. A., Schneider, S., Oliver, A., Marson, D., Geldmacher, D., Love, M. N., Griffith, R., Clark, D., Brockington, J., Roberson, E., Grossman, H., Mitsis, E., Shah, R. C., Detoledo-Morrell, L., Duara, R., Greig-Custo, M. T., Barker, W., Onyike, C., D'Agostino, D., Kielb, S., Sadowski, M., Sheikh, M. O., Ulysse, A., Gaikwad, M., Murali Doraiswamy, P., Petrella, J. R., Borges-Neto, S., Wong, T. Z., Coleman, E., Arnold, S. E., Karlawish, J. H., Wolk, D. A., Clark, C. M., Smith, C. D., Jicha, G., Hardy, P., Sinha, P., Oates, E., Conrad, G., Lopez, O. L., Oakley, M. A., Simpson, D. M., Porsteinsson, A. P., Goldstein, B. S., Martin, K., Makino, K. M., Ismail, M. S., Brand, C., Preda, A., Nguyen, D., Womack, K., Mathews, D., Quiceno, M., Levey, A. I., Lah, J. J., Cellar, J. S., Burns, J. M., Swerdlow, R. H., Brooks, W. M., Apostolova, L., Tingus, K., Woo, E., Silverman, D. H. S., Lu, P. H., Bartzokis, G., Graff-Radford, N. R., Parfitt, F., Poki-Walker, K., Farlow, M. R., Marie Hake, A., Matthews, B., Brosch, J. R., Herring, S., Van Dyck, C. H., Carson, R. E., MacAvoy, M. G., Varma, P., Chertkow, H., Bergman, H., Hosein, C., Black, S., Stefanovic, B., Caldwell, C., Robin Hsiung, G. Y., Mudge, B., Sossi, V., Feldman, H., Assaly, M., Finger, E., Pasternack, S., Rachisky, I., Rogers, J., Trost, D., Kertesz, A., Bernick, C., Munic, D., Rogalski, E., Lipowski, K., Weintraub, S., Bonakdarpour, B., Kerwin, D., Wu, C. K., Johnson, N., Sadowsky, C., Villena, T., Scott Turner, R., Johnson, K., Reynolds, B., Sperling, R. A., Johnson, K. A., Marshall, G., Yesavage, J., Taylor, J. L., Lane, B., Rosen, A., Tinklenberg, J., Sabbagh, M. N., Belden, C. M., Jacobson, S. A., Sirrel, S. A., Kowall, N., Killiany, R., Budson, A. E., Norbash, A., Lynn Johnson, P., Obisesan, T. O., Wolday, S., Allard, J., Lerner, A., Ogrocki, P., Tatsuoka, C., Fatica, P., Fletcher, E., Maillard, P., Olichney, J., Decarli, C., Carmichael, O., Kittur, S., Borrie, M., Lee, T. Y., Bartha, R., Johnson, S., Asthana, S., Carlsson, C. M., Tariot, P., Burke, A., Milliken, A. M., Trncic, N., Fleisher, A., Reeder, S., Bates, V., Capote, H., Rainka, M., Scharre, D. W., Kataki, M., Kelly, B., Zimmerman, E. A., Celmins, D., Brown, A. D., Pearlson, G. D., Blank, K., Anderson, K., Flashman, L. A., Seltzer, M., Hynes, M. L., Santulli, R. B., Sink, K. M., Gordineer, L., Williamson, J. D., Garg, P., Watkins, F., Ott, B. R., Tremont, G., Daiello, L. A., Salloway, S., Malloy, P., Correia, S., Rosen, H. J., Miller, B. L., Perry, D., Mintzer, J., Spicer, K., Bachman, D., Pomara, N., Hernando, R., Sarrael, A., Schultz, S. K., Ekstam Smith, K., Koleva, H., Nam, K. W., Shim, H., Relkin, N., Chaing, G., Lin, M., Ravdin, L., Smith, A., Ashok Raj, B. & Fargher, K., Dec 1 2017, In : Scientific reports. 7, 1, 14052.

Research output: Contribution to journalArticle

4 Scopus citations

On the horizon: Pathways for drug development in Alzheimer's disease

Hake, A. M. & Farlow, M. R., Feb 2004, In : Clinics in Geriatric Medicine. 20, 1, p. 141-152 12 p.

Research output: Contribution to journalReview article

1 Scopus citations

Oculomotor control in asymptomatic and recently diagnosed individuals with the genetic marker for Huntington's disease

Blekher, T. M., Yee, R. D., Kirkwood, S. C., Hake, A. M., Stout, J. C., Weaver, M. R. & Foroud, T. M., Oct 1 2004, In : Vision Research. 44, 23, p. 2729-2736 8 p.

Research output: Contribution to journalArticle

62 Scopus citations

Non-coding variability at the APOE locus contributes to the Alzheimer’s risk

Alzheimer’s Disease Neuroimaging Initiative, Dec 1 2019, In : Nature communications. 10, 1, 3310.

Research output: Contribution to journalArticle

Open Access
5 Scopus citations

New concepts in the drug therapy of Alzheimer's disease

Hake, A. M. & Farlow, M. R., Dec 17 2001, In : Expert opinion on pharmacotherapy. 2, 12, p. 1975-1983 9 p.

Research output: Contribution to journalReview article

5 Scopus citations

Nail Selenium Level and Diabetes in Older People in Rural China

SU, L. Q., JIN, Y. L., Unverzagt, F., CHENG, Y. B., Hake, A., RAN, L., MA, F., LIU, J. Y., CHEN, C., BIAN, J. C., WU, X. P. & Gao, S., Nov 1 2016, In : Biomedical and Environmental Sciences. 29, 11, p. 818-824 7 p.

Research output: Contribution to journalLetter

7 Scopus citations

Multimodal Hippocampal Subfield Grading For Alzheimer’s Disease Classification

Alzheimer’s Disease Neuroimaging Initiative, Dec 1 2019, In : Scientific reports. 9, 1, 13845.

Research output: Contribution to journalArticle

Open Access
10 Scopus citations

Multimodal and Multiscale Deep Neural Networks for the Early Diagnosis of Alzheimer’s Disease using structural MR and FDG-PET images

Alzheimer’s Disease Neuroimaging Initiative, Dec 1 2018, In : Scientific reports. 8, 1, 5697.

Research output: Contribution to journalArticle

Open Access
54 Scopus citations
39 Scopus citations
8 Scopus citations

Longitudinal measurement and hierarchical classification framework for the prediction of Alzheimer's disease

Huang, M., Yang, W., Feng, Q., Chen, W., Weiner, M. W., Aisen, P., Petersen, R., Jack, C. R., Jagust, W., Trojanowki, J. Q., Toga, A. W., Beckett, L., Green, R. C., Saykin, A. J., Morris, J. C., Shaw, L. M., Kaye, J., Quinn, J., Silbert, L., Lind, B. & 219 others, Carter, R., Dolen, S., Schneider, L. S., Pawluczyk, S., Beccera, M., Teodoro, L., Spann, B. M., Brewer, J., Vanderswag, H., Fleisher, A., Heidebrink, J. L., Lord, J. L., Mason, S. S., Albers, C. S., Knopman, D., Johnson, K., Doody, R. S., Villanueva-Meyer, J., Chowdhury, M., Rountree, S., Dang, M., Stern, Y., Honig, L. S., Bell, K. L., Ances, B., Carroll, M., Creech, M. L., Franklin, E., Mintun, M. A., Schneider, S., Oliver, A., Marson, D., Griffith, R., Clark, D., Geldmacher, D., Brockington, J., Roberson, E., Love, M. N., Grossman, H., Mitsis, E., Shah, R. C., DeToledo-Morrell, L., Duara, R., Varon, D., Greig, M. T., Roberts, P., Albert, M., Onyike, C., D'Agostino, D., Kielb, S., Galvin, J. E., Cerbone, B., Michel, C. A., Pogorelec, D. M., Rusinek, H., De Leon, M. J., Glodzik, L., De Santi, S., Murali Doraiswamy, P., Petrella, J. R., Borges-Neto, S., Wong, T. Z., Coleman, E., Smith, C. D., Jicha, G., Hardy, P., Sinha, P., Oates, E., Conrad, G., Porsteinsson, A. P., Goldstein, B. S., Martin, K., Makino, K. M., Saleem Ismail, M., Brand, C., Mulnard, R. A., Thai, G., Mc-Adams-Ortiz, C., Womack, K., Mathews, D., Quiceno, M., Levey, A. I., Lah, J. J., Cellar, J. S., Burns, J. M., Swerdlow, R. H., Brooks, W. M., Apostolova, L., Tingus, K., Woo, E., Silverman, D. H. S., Lu, P. H., Bartzokis, G., Graff-Radford, N. R., Parfitt, F., Kendall, T., Johnson, H., Farlow, M. R., Hake, A. M., Brosch, J. R., Herring, S., Hunt, C., Van Dyck, C. H., Carson, R. E., MacAvoy, M. G., Varma, P., Chertkow, H., Bergman, H., Hosein, C., Black, S., Stefanovic, B., Caldwell, C., Hsiung, G. Y. R., Feldman, H., Mudge, B., Assaly, M., Finger, E., Pasternack, S., Rachisky, I., Trost, D., Kertesz, A., Bernick, C., Munic, D., Mesulam, M. M., Lipowski, K., Weintraub, S., Bonakdarpour, B., Kerwin, D., Wu, C. K., Johnson, N., Sadowsky, C., Villena, T., Turner, R. S., Reynolds, B., Sperling, R. A., Johnson, K. A., Marshall, G., Yesavage, J., Taylor, J. L., Lane, B., Rosen, A., Tinklenberg, J., Sabbagh, M. N., Belden, C. M., Jacobson, S. A., Sirrel, S. A., Kowall, N., Killiany, R., Budson, A. E., Norbash, A., Lynn Johnson, P., Obisesan, T. O., Wolday, S., Allard, J., Lerner, A., Ogrocki, P., Tatsuoka, C., Fatica, P., Maillard, P., Olichney, J., DeCarli, C., Carmichael, O., Kittur, S., Borrie, M., Lee, T. Y., Bartha, R., Johnson, S., Asthana, S., Carlsson, C. M., Potkin, S. G., Preda, A., Nguyen, D., Tariot, P., Burke, A., Trncic, N., Reeder, S., Bates, V., Capote, H., Rainka, M., Scharre, D. W., Kataki, M., Adeli, A., Zimmerman, E. A., Celmins, D., Brown, A. D., Pearlson, G. D., Blank, K., Anderson, K., Flashman, L. A., Seltzer, M., Hynes, M. L., Santulli, R. B., Sink, K. M., Gordineer, L., Williamson, J. D., Garg, P., Watkins, F., Ott, B. R., Querfurth, H., Tremont, G., Salloway, S., Malloy, P., Correia, S., Rosen, H. J., Miller, B. L., Perry, D., Mintzer, J., Spicer, K., Bachman, D., Pomara, N., Hernando, R., Sarrael, A., Relkin, N., Chaing, G., Lin, M., Ravdin, L., Smith, A., Raj, B. A. & Fargher, K., Jan 12 2017, In : Scientific reports. 7, 39880.

Research output: Contribution to journalArticle

27 Scopus citations

Longitudinal association between selenium levels and hypertension in a rural elderly Chinese cohort

Su, L., Jin, Y., Unverzagt, F. W., Liang, C., Cheng, Y., Hake, A. M., Kuruppu, D., Ma, F., Liu, J., Chen, C., Bian, J., Li, P. & Gao, S., Dec 1 2016, In : Journal of Nutrition, Health and Aging. 20, 10, p. 983-988 6 p.

Research output: Contribution to journalArticle

11 Scopus citations

Lasmiditan mechanism of action - Review of a selective 5-HT1Fagonist

Clemow, D. B., Johnson, K. W., Hochstetler, H. M., Ossipov, M. H., Hake, A. M., Hake, A. M. & Blumenfeld, A. M., Jun 10 2020, In : Journal of Headache and Pain. 21, 1, 71.

Research output: Contribution to journalReview article

Open Access

Incidence and risk factors for cognitive impairment no dementia and mild cognitive impairment in African Americans

Unverzagt, F. W., Ogunniyi, A., Taler, V., Gao, S., Lane, K. A., Baiyewu, O., Gureje, O., Smith-Gamble, V., Hake, A., Hendrie, H. C. & Hall, K. S., Jan 2011, In : Alzheimer disease and associated disorders. 25, 1, p. 4-10 7 p.

Research output: Contribution to journalArticle

27 Scopus citations

Improvement in Function after Lasmiditan Treatment: Post Hoc Analysis of Data from Phase 3 Studies

Smith, T., Krege, J. H., Rathmann, S. S., Dowsett, S. A., Hake, A., Nery, E. S. M., Matthews, B. R. & Doty, E. G., 2020, (Accepted/In press) In : Neurology and Therapy.

Research output: Contribution to journalArticle

Open Access

Implementing innovative models of dementia care: The Healthy Aging Brain Center

Boustani, M. A., Sachs, G. A., Alder, C. A., Munger, S., Schubert, C. C., Guerriero Austrom, M., Hake, A. M., Unverzagt, F. W., Farlow, M., Matthews, B. R., Perkins, A. J., Beck, R. A. & Callahan, C. M., Jan 2011, In : Aging and Mental Health. 15, 1, p. 13-22 10 p.

Research output: Contribution to journalArticle

76 Scopus citations

Homocysteine levels and dementia risk in Yoruba and African Americans

Hendrie, H. C., Baiyewu, O., Lane, K. A., Purnell, C., Gao, S., Hake, A., Ogunniyi, A., Gureje, O., Unverzagt, F. W., Murrell, J., Deeg, M. A. & Hall, K., Nov 1 2013, In : International Psychogeriatrics. 25, 11, p. 1859-1866 8 p.

Research output: Contribution to journalArticle

7 Scopus citations

Genome-wide association analysis of hippocampal volume identifies enrichment of neurogenesis-related pathways

Alzheimer’s Disease Neuroimaging Initiative (ADNI), Dec 1 2019, In : Scientific reports. 9, 1, 14498.

Research output: Contribution to journalArticle

Open Access
4 Scopus citations

Functional brain architecture is associated with the rate of tau accumulation in Alzheimer’s disease

Alzheimer’s Disease Neuroimaging Initiative (ADNI), Dec 1 2020, In : Nature communications. 11, 1, 347.

Research output: Contribution to journalArticle

Open Access
5 Scopus citations

Florbetapir positron emission tomography and cerebrospinal fluid biomarkers

Alzheimer's Disease Neuroimaging Initiative, Aug 1 2015, In : Alzheimer's and Dementia. 11, 8, p. 986-993 8 p., 1970.

Research output: Contribution to journalArticle

12 Scopus citations

Ferritin levels in the cerebrospinal fluid predict Alzheimer's disease outcomes and are regulated by APOE

Alzheimer's Disease Neuroimaging Initiative, May 19 2015, In : Nature communications. 6, 6760.

Research output: Contribution to journalArticle

118 Scopus citations

FAM222A encodes a protein which accumulates in plaques in Alzheimer’s disease

The Alzheimer Disease Neuroimaging Initiative, Dec 1 2020, In : Nature communications. 11, 1, 411.

Research output: Contribution to journalArticle

Open Access
2 Scopus citations

Estrogen for Alzheimer's disease in women: Randomized, double-blind, placebo-controlled trial

Henderson, V. W., Paganini-Hill, A., Miller, B. L., Elble, R. J., Reyes, P. F., Shoupe, D., McCleary, C. A., Klein, R. A., Hake, A. M. & Farlow, M. R., Jan 25 2000, In : Neurology. 54, 2, p. 295-301 7 p.

Research output: Contribution to journalArticle

495 Scopus citations

Efficacy and safety of galantamine in patients with dementia with Lewy bodies: A 24-week open-label study

Edwards, K., Royall, D., Hershey, L., Lichter, D., Hake, A., Farlow, M., Pasquier, F. & Johnson, S., May 1 2007, In : Dementia and Geriatric Cognitive Disorders. 23, 6, p. 401-405 5 p.

Research output: Contribution to journalArticle

62 Scopus citations

Effect of diabetes on caregiver burden in an observational study of individuals with Alzheimer's disease

Lebrec, J., Ascher-Svanum, H., Chen, Y. F., Reed, C., Kahle-Wrobleski, K., Hake, A. M., Raskin, J., Naderali, E., Schuster, D., Heine, R. J. & Kendall, D. M., May 3 2016, In : BMC Geriatrics. 16, 1, 93.

Research output: Contribution to journalArticle

8 Scopus citations

Early role of vascular dysregulation on late-onset Alzheimer's disease based on multifactorial data-driven analysis

The Alzheimer's Disease Neuroimaging Initiative, Jun 21 2016, In : Nature communications. 7, 11934.

Research output: Contribution to journalArticle

301 Scopus citations