Anna De Paoli-Roach

  • 7531 Citations
  • 50 h-Index
1974 …2019
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  • 4 Similar Profiles
Glycogen Synthase Medicine & Life Sciences
Phosphorylation Chemical Compounds
Glycogen Medicine & Life Sciences
Muscle Chemical Compounds
Protein Phosphatase 1 Medicine & Life Sciences
Rabbits Medicine & Life Sciences
Phosphoprotein Phosphatases Medicine & Life Sciences
Protein Kinases Medicine & Life Sciences

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Publications 1974 2019

  • 7531 Citations
  • 50 h-Index
  • 147 Article
  • 3 Chapter

Pathologic gene network rewiring implicates PPP1R3A as a central regulator in pressure overload heart failure

Cordero, P., Parikh, V. N., Chin, E. T., Erbilgin, A., Gloudemans, M. J., Shang, C., Huang, Y., Chang, A. C., Smith, K. S., Dewey, F., Zaleta, K., Morley, M., Brandimarto, J., Glazer, N., Waggott, D., Pavlovic, A., Zhao, M., Moravec, C. S., Tang, W. H. W., Skreen, J. & 15 others, Malloy, C., Hannenhalli, S., Li, H., Ritter, S., Li, M., Bernstein, D., Connolly, A., Hakonarson, H., Lusis, A. J., Margulies, K. B., De Paoli-Roach, A., Montgomery, S. B., Wheeler, M. T., Cappola, T. & Ashley, E. A., Dec 1 2019, In : Nature communications. 10, 1, 2760.

Research output: Contribution to journalArticle

Open Access
Gene Regulatory Networks
regulators
genes
Heart Failure
Genes
2 Citations (Scopus)

Targeting Pathogenic Lafora Bodies in Lafora Disease Using an Antibody-Enzyme Fusion

Brewer, M. K., Uittenbogaard, A., Austin, G. L., Segvich, D. M., DePaoli-Roach, A., Roach, P. J., McCarthy, J. J., Simmons, Z. R., Brandon, J. A., Zhou, Z., Zeller, J., Young, L. E. A., Sun, R. C., Pauly, J. R., Aziz, N. M., Hodges, B. L., McKnight, T. R., Armstrong, D. D. & Gentry, M. S., Oct 1 2019, In : Cell Metabolism. 30, 4, p. 689-705.e6

Research output: Contribution to journalArticle

Lafora Disease
Antibodies
Immunoglobulin Isotypes
Enzymes
Glycogen
10 Citations (Scopus)

Lack of liver glycogen causes hepatic insulin resistance and steatosis in mice

Irimia, J. M., Meyer, C. M., Segvich, D. M., Surendran, S., De Paoli-Roach, A., Morral, N. & Roach, P., 2017, In : Journal of Biological Chemistry. 292, 25, p. 10455-10464 10 p.

Research output: Contribution to journalArticle

Liver Glycogen
Insulin Resistance
Insulin
Liver
Phosphorylation
5 Citations (Scopus)

Novel method for detection of glycogen in cells

Skurat, A., Segvich, D. M., De Paoli-Roach, A. & Roach, P., May 1 2017, In : Glycobiology. 27, 5, p. 416-424 9 p.

Research output: Contribution to journalArticle

Glycogen
Glycogen Storage Disease Type II
Glycogen Storage Disease
Glucans
Metabolism
2 Citations (Scopus)

Redox Switch for the Inhibited State of Yeast Glycogen Synthase Mimics Regulation by Phosphorylation

Mahalingan, K. K., Baskaran, S., De Paoli-Roach, A., Roach, P. & Hurley, T., Jan 10 2017, In : Biochemistry. 56, 1, p. 179-188 10 p.

Research output: Contribution to journalArticle

Glycogen Synthase
Phosphorylation
Yeast
Oxidation-Reduction
Yeasts