Anna De Paoli-Roach

  • 7733 Citations
  • 50 h-Index
1974 …2020

Research output per year

If you made any changes in Pure these will be visible here soon.

Publications

  • 7733 Citations
  • 50 h-Index
  • 144 Article
  • 3 Chapter
  • 3 Comment/debate
  • 2 Review article
2003

Protein Phosphatase 1 Binding Proteins

DePaoli-Roach, A. A., Nov 7 2003, Handbook of Cell Signaling. Elsevier Inc., Vol. 1-3. p. 613-619 7 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

8 Scopus citations
2002

Cyclin G2 associates with protein phosphatase 2A catalytic and regulatory B′ subunits in active complexes and induces nuclear aberrations and a G1/S phase cell cycle arrest

Bennin, D. A., Arachchige Don, A. S., Brake, T., McKenzie, J. L., Rosenbaum, H., Ortiz, L., Depaoli-Roach, A. A. & Horne, M. C., Jul 26 2002, In : Journal of Biological Chemistry. 277, 30, p. 27449-27467 19 p.

Research output: Contribution to journalArticle

159 Scopus citations
1 Scopus citations

Reversal of diet-induced glucose intolerance by hepatic expression of a variant glycogen-targeting subunit of protein phosphatase-1

Gasa, R., Clark, C., Yang, R., Depaoli-Roach, A. A. & Newgard, C. B., Jan 11 2002, In : Journal of Biological Chemistry. 277, 2, p. 1524-1530 7 p.

Research output: Contribution to journalArticle

20 Scopus citations

Type 1 phosphatase, a negative regulator of cardiac function

Carr, A. N., Schmidt, A. G., Suzuki, Y., Del Monte, F., Sato, Y., Lanner, C., Breeden, K., Jing, S. L., Allen, P. B., Greengard, P., Yatani, A., Hoit, B. D., Grupp, I. L., Hajjar, R. J., DePaoli-Roach, A. A. & Kranias, E. G., Jun 5 2002, In : Molecular and cellular biology. 22, 12, p. 4124-4135 12 p.

Research output: Contribution to journalArticle

208 Scopus citations
2001

Gene structure and expression of the targeting subunit, RGL, of the muscle-specific glycogen-associated type 1 protein phosphatase, PP1G

Lannér, C., Suzuki, Y., Bi, C. B., Zhang, H., Cooper, L. D., Bowker-Kinley, M. M., DePaoli-Roach, A. A. & Suzuki, Y., Apr 1 2001, In : Archives of Biochemistry and Biophysics. 388, 1, p. 135-145 11 p.

Research output: Contribution to journalArticle

15 Scopus citations

Insulin control of glycogen metabolism in knockout mice lacking the muscle-specific protein phosphatase pp1g/rgl

Suzuki, Y., Lanner, C., Kim, J. H., Giuseppe Vilardo, P., Zhang, H., Yang, J., Cooper, L. D., Steele, M., Kennedy, A., Bock, C. B., Scrimgeour, A., Lawrence, J. & Depaoli-Roach, A. A., Apr 10 2001, In : Molecular and cellular biology. 21, 8, p. 2683-2694 12 p.

Research output: Contribution to journalArticle

121 Scopus citations

The Muscle-specific Protein Phosphatase PP1G/RGL(GM) Is Essential for Activation of Glycogen Synthase by Exercise

Aschenbach, W. G., Suzuki, Y., Breeden, K., Prats, C., Hirshman, M. F., Dufresne, S. D., Sakamoto, K., Vilardo, P. G., Steele, M., Kim, J. H., Jing, S. L., Goodyear, L. J. & DePaoli-Roach, A. A., Oct 26 2001, In : Journal of Biological Chemistry. 276, 43, p. 39959-39967 9 p.

Research output: Contribution to journalArticle

92 Scopus citations
2000

Cellular mechanisms regulating protein phosphatase-1. A key functional interaction between inhibitor-2 and the type 1 protein phosphatase catalytic subunit

Connor, J. H., Frederick, D., Huang, H. B., Yang, J., Helps, N. R., Cohen, P. T. W., Nairn, A. C., DePaoli-Roach, A., Tatchell, K. & Shenolikar, S., Jun 23 2000, In : Journal of Biological Chemistry. 275, 25, p. 18670-18675 6 p.

Research output: Contribution to journalArticle

50 Scopus citations

Decreased protein phosphatase 2A activity in hippocampal long-term potentiation

Fukunaga, K., Muller, D., Ohmitsu, M., Bakó, E., DePaoli-Roach, A. A. & Miyamoto, E., Jan 29 2000, In : Journal of Neurochemistry. 74, 2, p. 807-817 11 p.

Research output: Contribution to journalArticle

71 Scopus citations

Distinctive regulatory and metabolic properties of glycogen-targeting subunits of protein phosphatase-1 (PTG, G(L), G(M)/R(G1)) expressed in hepatocytes

Gasa, R., Jensen, P. B., Berman, H. K., Brady, M. J., Depaoli-Roach, A. A. & Newgard, C. B., Aug 25 2000, In : Journal of Biological Chemistry. 275, 34, p. 26396-26403 8 p.

Research output: Contribution to journalArticle

59 Scopus citations
52 Scopus citations

Structure and chromosomal localization of the human glycogenin-2 gene GYG2

Zhai, L., Mu, J., Zong, H., DePaoli-Roach, A. A. & Roach, P. J., Jan 25 2000, In : Gene. 242, 1-2, p. 229-235 7 p.

Research output: Contribution to journalArticle

10 Scopus citations
1999

Phosphorylation-dependent inhibition of protein phosphatase-1 by G- substrate: A purkinje cell substrate of the cyclic GMP-dependent protein kinase

Hall, K. U., Collins, S. P., Gamm, D. M., Massa, E., DePaoli-Roach, A. A. & Uhler, M. D., Feb 5 1999, In : Journal of Biological Chemistry. 274, 6, p. 3485-3495 11 p.

Research output: Contribution to journalArticle

62 Scopus citations
1998

Targeted overexpression of phospholamban to mouse atrium depresses Ca2+ transport and contractility

Neumann, J., Boknik, P., DePaoli-Roach, A. A., Field, L. J., Rockman, H. A., Kobayashi, Y. M., Kelley, J. S. & Jones, L. R., Oct 1998, In : Journal of Molecular and Cellular Cardiology. 30, 10, p. 1991-2002 12 p.

Research output: Contribution to journalArticle

29 Scopus citations
1997
54 Scopus citations

Saccharomyces cerevisiae homologs of mammalian B and B' subunits of protein phosphatase 2A direct the enzyme to distinct cellular functions

Zhao, Y., Boguslawski, G., Zitomer, R. S. & DePaoli-Roach, A. A., Mar 28 1997, In : Journal of Biological Chemistry. 272, 13, p. 8256-8262 7 p.

Research output: Contribution to journalArticle

89 Scopus citations

The B' γ subunit of protein phosphatase 2A is phosphorylated by cGMP-dependent protein kinase

Komalavilas, P., DePaoli-Roach, A. A. & Lincoln, T. M., Dec 1 1997, In : FASEB Journal. 11, 3, p. A326

Research output: Contribution to journalArticle

1996

Dephosphorylation of Sp1 by protein phosphatase 1 is involved in the glucose-mediated activation of the acetyl-CoA carboxylase gene

Daniel, S., Zhang, S., DePaoli-Roach, A. A. & Kim, K. H., Jul 2 1996, In : Journal of Biological Chemistry. 271, 25, p. 14692-14697 6 p.

Research output: Contribution to journalArticle

130 Scopus citations

High complexity in the expression of the B′ subunit of protein phosphatase 2A0: Evidence for the existence of at least seven novel isoforms

Csortos, C., Zolnierowicz, S., Bakó, E., Durbin, S. D. & DePaoli-Roach, A. A., Feb 2 1996, In : Journal of Biological Chemistry. 271, 5, p. 2578-2588 11 p.

Research output: Contribution to journalArticle

Open Access
154 Scopus citations
Open Access
152 Scopus citations
1995

Casein kinase Iγ subfamily: Molecular cloning, expression, and characterization of three mammalian isoforms and complementation of defects in the Saccharomyces cerevisiae YCK genes

Zhai, L., Graves, P. R., Robinson, L. C., Italiano, M., Culbertson, M. R., Rowles, J., Cobb, M. H., DePaoli-Roach, A. A. & Roach, P. J., May 26 1995, In : Journal of Biological Chemistry. 270, 21, p. 12717-12724 8 p.

Research output: Contribution to journalArticle

Open Access
88 Scopus citations

Phosphorylation and activation of the ATP-Mg-dependent protein phosphatase by the mitogen-activated protein kinase

Wang, Q. M., Guan, K. L., Roach, P. J. & DePaoli-Roach, A. A., Jan 1 1995, In : Journal of Biological Chemistry. 270, 31, p. 18352-18358 7 p.

Research output: Contribution to journalArticle

41 Scopus citations

The G-protein-coupled receptor phosphatase: A protein phosphatase type 2A with a distinct subcellular distribution and substrate specificity

Pitcher, J. A., Payne, E. S., Csortos, C., Depaoli-Roach, A. A. & Lefkowitz, R. J., Aug 29 1995, In : Proceedings of the National Academy of Sciences of the United States of America. 92, 18, p. 8343-8347 5 p.

Research output: Contribution to journalArticle

150 Scopus citations
1994

Characterization of the PP2Aα gene mutation in okadaic acid-resistant variants of CHO-K1 cells

Shima, H., Tohda, H., Aonuma, S., Nakayasu, M., Depaoli-Roach, A. A., Sugimura, T. & Nagao, M., Sep 27 1994, In : Proceedings of the National Academy of Sciences of the United States of America. 91, 20, p. 9267-9271 5 p.

Research output: Contribution to journalArticle

Open Access
44 Scopus citations

Diversity in the Regulatory B-Subunits of Protein Phosphatase 2A: Identification of a Novel Isoform Highly Expressed in Brain

Zolnierowicz, S., Csortos, C., Bondor, J., Verin, A., Mumby, M. C. & DePaoli-Roach, A. A., Oct 1 1994, In : Biochemistry. 33, 39, p. 11858-11867 10 p.

Research output: Contribution to journalArticle

92 Scopus citations

Domains of phosphatase inhibitor-2 involved in the control of the ATP-Mg- dependent protein phosphatase

Park, I. K. & DePaoli-Roach, A. A., Jan 1 1994, In : Journal of Biological Chemistry. 269, 46, p. 28919-28928 10 p.

Research output: Contribution to journalArticle

60 Scopus citations

Glycogen synthase kinase-3β is a dual specificity kinase differentially regulated by tyrosine and serine/threonine phosphorylation

Wang, Q. M., Fiol, C. J., DePaoli-Roach, A. A. & Roach, P. J., May 20 1994, In : Journal of Biological Chemistry. 269, 20, p. 14566-14574 9 p.

Research output: Contribution to journalArticle

238 Scopus citations

In vivo regulation of protein kinase C by trans-phosphorylation followed by autophosphorylation

Dutil, E. M., Keranen, L. M., DePaoli-Roach, A. A. & Newton, A. C., Nov 25 1994, In : Journal of Biological Chemistry. 269, 47, p. 29359-29362 4 p.

Research output: Contribution to journalArticle

137 Scopus citations

Isoform Differences in Substrate Recognition by Glycogen Synthase Kinases 3α and 3β in the Phosphorylation of Phosphatase Inhibitor 2

Wang, Q. M., Park, I. K., Fiol, C. J., Roach, P. J. & DePaoli-Roach, A. A., Jan 1 1994, In : Biochemistry. 33, 1, p. 143-147 5 p.

Research output: Contribution to journalArticle

61 Scopus citations
71 Scopus citations

Native cytosolic protein phosphatase-1 (PP-1S) containing modulator (inhibitor-2) is an active enzyme

Bollen, M., DePaoli-Roach, A. A. & Stalmans, W., May 16 1994, In : FEBS Letters. 344, 2-3, p. 196-200 5 p.

Research output: Contribution to journalArticle

16 Scopus citations

Serine/threonine protein phosphatases in the control of cell function

Depaoli-Roach, A. A., Park, I. K., Cerovsky, V., Csortos, C., Durbin, S. D., Kuntz, M. J., Sitikov, A., Tang, P. M., Verin, A. & Zolnierowicz, S., 1994, In : Advances in Enzyme Regulation. 34, C, p. 199-224 26 p.

Research output: Contribution to journalArticle

121 Scopus citations
1993

Characterization of rabbit skeletal muscle glycogenin. Tyrosine 194 is essential for function

Cao, Y., Mahrenholz, A. M., DePaoli-Roach, A. A. & Roach, P. J., Jan 1 1993, In : Journal of Biological Chemistry. 268, 20, p. 14687-14693 7 p.

Research output: Contribution to journalArticle

61 Scopus citations

Initiation of glycogen synthesis. Control of glycogenin by glycogen phosphorylase

Cao, Y., Skurat, A. V., DePaoli-Roach, A. A. & Roach, P. J., Jan 1 1993, In : Journal of Biological Chemistry. 268, 29, p. 21717-21721 5 p.

Research output: Contribution to journalArticle

20 Scopus citations

Mechanisms of multisite phosphorylation and inactivation of rabbit muscle glycogen synthase

Zhang, W. M., DePaoli-Roach, A. A. & Roach, P. J., Jan 1 1993, In : Archives of Biochemistry and Biophysics. 304, 1, p. 219-225 7 p.

Research output: Contribution to journalArticle

64 Scopus citations

Molecular cloning, expression, and characterization of a 49-kilodalton casein kinase I isoform from rat testis

Graves, P. R., Haas, D. W., Hagedorn, C. H., DePaoli-Roach, A. A. & Roach, P. J., Jan 1 1993, In : Journal of Biological Chemistry. 268, 9, p. 6394-6401 8 p.

Research output: Contribution to journalArticle

114 Scopus citations

Protein kinase A modulates an endogenous calcium channel, but not the calcium-activated chloride channel, in Xenopus oocytes

Chen, Y., Pollock, J. D., Wang, Y., DePaoli-Roach, A. A. & Yu, L., Dec 27 1993, In : FEBS Letters. 336, 2, p. 191-196 6 p.

Research output: Contribution to journalArticle

6 Scopus citations
1992

Metabolic effects of proglycosyn

Yamanouchi, K., Stephens, T. W., Chikada, K., Dominianni, S. J., Behforouz, H., Scislowski, P., DePaoli-Roach, A., Allmann, D. W. & Harris, R. A., May 1 1992, In : Archives of Biochemistry and Biophysics. 294, 2, p. 609-615 7 p.

Research output: Contribution to journalArticle

8 Scopus citations

Multiple roles for protein phosphatase 1 in regulating the Xenopus early embryonic cell cycle

Walker, D. H., DePaoli-Roach, A. A. & Maller, J. L., Jan 1 1992, In : Molecular Biology of the Cell. 3, 6, p. 687-698 12 p.

Research output: Contribution to journalArticle

38 Scopus citations

Rabbit skeletal muscle glycogenin. Molecular cloning and production of fully functional protein in Escherichia coli

Viskupic, E., Cao, Y., Zhang, W., Cheng, C., DePaoli-Roach, A. A. & Roach, P. J., Dec 1 1992, In : Journal of Biological Chemistry. 267, 36, p. 25759-25763 5 p.

Research output: Contribution to journalArticle

52 Scopus citations

Recombinant rabbit muscle casein kinase I α is inhibited by heparin and activated by polylysine

Zhai, L., Graves, P. R., Longenecker, K. L., DePaoli-Roach, A. A. & Roach, P. J., Dec 15 1992, In : Biochemical and Biophysical Research Communications. 189, 2, p. 944-949 6 p.

Research output: Contribution to journalArticle

25 Scopus citations

Yeast casein kinase I homologues: An essential gene pair

Robinson, L. C., Hubbard, E. J. A., Graves, P. R., DePaoli-Roach, A. A., Roach, P. J., Kung, C., Haas, D. W., Hagedorn, C. H., Goebl, M., Culbertson, M. R. & Carlson, M., Jan 1 1992, In : Proceedings of the National Academy of Sciences of the United States of America. 89, 1, p. 28-32 5 p.

Research output: Contribution to journalArticle

Open Access
102 Scopus citations
1991

CDC55, a Saccharomyces cerevisiae gene involved in cellular morphogenesis: Identification, characterization, and homology to the B subunit of mammalian type 2A protein phosphatase

Healy, A. M., Zolnierowicz, S., Stapleton, A. E., Goebl, M., Depaoli-Roach, A. A. & Pringle, J. R., Nov 1991, In : Molecular and cellular biology. 11, 11, p. 5767-5780 14 p.

Research output: Contribution to journalArticle

Open Access
221 Scopus citations

Fluorescence Studies on the Interaction of Inhibitor 2 and Okadaic Acid with the Catalytic Subunit of Type 1 Phosphoprotein Phosphatases

Picking, W. D., Kudlicki, W., Kramer, G., Hardesty, B., Vandenheede, J. R., Merlevede, W., Park, I. K. & DePaoli-Roach, A., Oct 1 1991, In : Biochemistry. 30, 42, p. 10280-10287 8 p.

Research output: Contribution to journalArticle

31 Scopus citations

Glycogen metabolism and signal transduction in mammals and yeast

Roach, P. J., Cao, Y., Corbett, C. A., DePaoli-Roach, A. A., Farkas, I., Fiol, C. J., Flotow, H., Graves, P. R., Hardy, T. A., Hrubey, T. W., Viskupic, E. & Zhang, W., 1991, In : Advances in Enzyme Regulation. 31, C, p. 101-120 20 p.

Research output: Contribution to journalArticle

15 Scopus citations

Molecular cloning and expression of the regulatory (R(Gl)) subunit of the glycogen-associated protein phosphatase

Tang, P. M., Bondor, J. A., Swiderek, K. M. & DePaoli-Roach, A. A., Oct 29 1991, In : Journal of Biological Chemistry. 266, 24, p. 15782-15789 8 p.

Research output: Contribution to journalArticle

144 Scopus citations
1990

Isolation of the GSY1 gene encoding yeast glycogen synthase and evidence for the existence of a second gene

Farkas, I., Hardy, T. A., DePaoli-Roach, A. A. & Roach, P. J., Dec 1 1990, In : Journal of Biological Chemistry. 265, 34, p. 20879-20886 8 p.

Research output: Contribution to journalArticle

50 Scopus citations
1989

Primary structure of rabbit skeletal muscle glycogen synthase deduced from cDNA clones

Zhang, W., Browner, M. F., Fletterick, R. J., DePaoli-Roach, A. A. & Roach, P. J., 1989, In : FASEB Journal. 3, 13, p. 2532-2536 5 p.

Research output: Contribution to journalArticle

28 Scopus citations
1988

Identification of phosphorylation sites in peptides using a gas-phase sequencer

Wang, Y., Fiol, C. J., DePaoli-Roach, A. A., Bell, A. W., Hermodson, M. A. & Roach, P. J., Nov 1 1988, In : Analytical biochemistry. 174, 2, p. 537-547 11 p.

Research output: Contribution to journalArticle

40 Scopus citations