Anna De Paoli-Roach

  • 7591 Citations
  • 50 h-Index
1974 …2020
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Publications 1974 2020

  • 7591 Citations
  • 50 h-Index
  • 148 Article
  • 3 Chapter
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Article
2020

Accurate and sensitive quantitation of glucose and glucose phosphates derived from storage carbohydrates by mass spectrometry

Young, L. E. A., Brizzee, C. O., Macedo, J. K. A., Murphy, R. D., Contreras, C. J., DePaoli-Roach, A. A., Roach, P. J., Gentry, M. S. & Sun, R. C., Feb 15 2020, In : Carbohydrate Polymers. 230, 115651.

Research output: Contribution to journalArticle

Carbohydrates
Mass spectrometry
Glucose
Glycogen
Phosphates
2019

Pathologic gene network rewiring implicates PPP1R3A as a central regulator in pressure overload heart failure

Cordero, P., Parikh, V. N., Chin, E. T., Erbilgin, A., Gloudemans, M. J., Shang, C., Huang, Y., Chang, A. C., Smith, K. S., Dewey, F., Zaleta, K., Morley, M., Brandimarto, J., Glazer, N., Waggott, D., Pavlovic, A., Zhao, M., Moravec, C. S., Tang, W. H. W., Skreen, J. & 15 others, Malloy, C., Hannenhalli, S., Li, H., Ritter, S., Li, M., Bernstein, D., Connolly, A., Hakonarson, H., Lusis, A. J., Margulies, K. B., Depaoli-Roach, A. A., Montgomery, S. B., Wheeler, M. T., Cappola, T. & Ashley, E. A., Dec 1 2019, In : Nature communications. 10, 1, 2760.

Research output: Contribution to journalArticle

Open Access
Gene Regulatory Networks
regulators
genes
Heart Failure
Genes
2 Citations (Scopus)

Targeting Pathogenic Lafora Bodies in Lafora Disease Using an Antibody-Enzyme Fusion

Brewer, M. K., Uittenbogaard, A., Austin, G. L., Segvich, D. M., DePaoli-Roach, A., Roach, P. J., McCarthy, J. J., Simmons, Z. R., Brandon, J. A., Zhou, Z., Zeller, J., Young, L. E. A., Sun, R. C., Pauly, J. R., Aziz, N. M., Hodges, B. L., McKnight, T. R., Armstrong, D. D. & Gentry, M. S., Oct 1 2019, In : Cell Metabolism. 30, 4, p. 689-705.e6

Research output: Contribution to journalArticle

Lafora Disease
Antibodies
Immunoglobulin Isotypes
Enzymes
Glycogen
2017
10 Citations (Scopus)

Lack of liver glycogen causes hepatic insulin resistance and steatosis in mice

Irimia, J. M., Meyer, C. M., Segvich, D. M., Surendran, S., De Paoli-Roach, A., Morral, N. & Roach, P., 2017, In : Journal of Biological Chemistry. 292, 25, p. 10455-10464 10 p.

Research output: Contribution to journalArticle

Liver Glycogen
Insulin Resistance
Insulin
Liver
Phosphorylation
5 Citations (Scopus)

Novel method for detection of glycogen in cells

Skurat, A., Segvich, D. M., De Paoli-Roach, A. & Roach, P., May 1 2017, In : Glycobiology. 27, 5, p. 416-424 9 p.

Research output: Contribution to journalArticle

Glycogen
Glycogen Storage Disease Type II
Glycogen Storage Disease
Glucans
Metabolism
2 Citations (Scopus)

Redox Switch for the Inhibited State of Yeast Glycogen Synthase Mimics Regulation by Phosphorylation

Mahalingan, K. K., Baskaran, S., De Paoli-Roach, A., Roach, P. & Hurley, T., Jan 10 2017, In : Biochemistry. 56, 1, p. 179-188 10 p.

Research output: Contribution to journalArticle

Glycogen Synthase
Phosphorylation
Yeast
Oxidation-Reduction
Yeasts
2016
8 Citations (Scopus)

Incorporation of phosphate into glycogen by glycogen synthase

Contreras, C. J., Segvich, D. M., Mahalingan, K., Chikwana, V. M., Kirley, T. L., Hurley, T., De Paoli-Roach, A. & Roach, P., May 1 2016, In : Archives of Biochemistry and Biophysics. 597, p. 21-29 9 p.

Research output: Contribution to journalArticle

Glycogen Synthase
Glycogen
Phosphates
Phosphorylation
Uridine Diphosphate
4 Citations (Scopus)

Protein targeting to glycogen is a master regulator of glycogen synthesis in astrocytes

Ruchti, E., Roach, P., De Paoli-Roach, A., Magistretti, P. J. & Allaman, I., Dec 1 2016, In : IBRO Reports. 1, p. 46-53 8 p.

Research output: Contribution to journalArticle

Protein Transport
Glycogen
Astrocytes
Down-Regulation
Adenoviridae
19 Citations (Scopus)

Glycogen phosphomonoester distribution in mouse models of the progressive myoclonic epilepsy, Lafora disease

De Paoli-Roach, A., Contreras, C. J., Segvich, D. M., Heiss, C., Ishihara, M., Azadi, P. & Roach, P., Jan 1 2015, In : Journal of Biological Chemistry. 290, 2, p. 841-850 10 p.

Research output: Contribution to journalArticle

Lafora Disease
Progressive Myoclonic Epilepsy
Glycogen
Phosphorylation
Phosphates
10 Citations (Scopus)

Muscle glycogen remodeling and glycogen phosphate metabolism following exhaustive exercise of wild type and laforin knockout mice

Irimia, J. M., Tagliabracci, V. S., Meyer, C. M., Segvich, D. M., De Paoli-Roach, A. & Roach, P., Sep 11 2015, In : Journal of Biological Chemistry. 290, 37, p. 22686-22698 13 p.

Research output: Contribution to journalArticle

Glycogen
Metabolism
Knockout Mice
Muscle
Phosphates
2014
20 Citations (Scopus)

Protein degradation and quality control in cells from laforin and malin knockout mice

Garyali, P., Segvich, D. M., De Paoli-Roach, A. & Roach, P., Jul 25 2014, In : Journal of Biological Chemistry. 289, 30, p. 20606-20614 9 p.

Research output: Contribution to journalArticle

Glycogen
Knockout Mice
Quality Control
Proteolysis
Quality control
43 Citations (Scopus)

Sterol regulatory element-binding protein-1 (SREBP-1) is required to regulate glycogen synthesis and gluconeogenic gene expression in mouse liver

Ruiz, R., Jideonwo, V., Ahn, M., Surendran, S., Tagliabracci, V. S., Hou, Y., Gamble, A., Kerner, J., Irimia-Dominguez, J. M., Puchowicz, M. A., De Paoli-Roach, A., Hoppel, C., Roach, P. & Morral, N., Feb 28 2014, In : Journal of Biological Chemistry. 289, 9, p. 5510-5517 8 p.

Research output: Contribution to journalArticle

Sterol Regulatory Element Binding Protein 1
Glycogen
Gene expression
Liver
Gene Expression
2013
13 Citations (Scopus)

Structural basis for 2'-phosphate incorporation into glycogen by glycogen synthase

Chikwana, V. M., Khanna, M., Baskaran, S., Tagliabracci, V. S., Contreras, C. J., De Paoli-Roach, A., Roach, P. & Hurley, T., Dec 24 2013, In : Proceedings of the National Academy of Sciences of the United States of America. 110, 52, p. 20976-20981 6 p.

Research output: Contribution to journalArticle

Glycogen Synthase
Glycogen
Phosphates
Uridine Diphosphate
Glucose
2012
267 Citations (Scopus)

Glycogen and its metabolism: Some new developments and old themes

Roach, P., De Paoli-Roach, A., Hurley, T. & Tagliabracci, V. S., Feb 1 2012, In : Biochemical Journal. 441, 3, p. 763-787 25 p.

Research output: Contribution to journalArticle

Glycogen
Metabolism
Glycogen Synthase
Epinephrine
Lafora Disease
15 Citations (Scopus)

Laforin and malin knockout mice have normal glucose disposal and insulin sensitivity

De Paoli-Roach, A., Segvich, D. M., Meyer, C. M., Rahimi, Y., Worby, C. A., Gentry, M. S. & Roach, P., Apr 2012, In : Human Molecular Genetics. 21, 7, p. 1604-1610 7 p., ddr598.

Research output: Contribution to journalArticle

Knockout Mice
Insulin Resistance
Lafora Disease
Glucose
Insulin
2011
19 Citations (Scopus)

Multiple glycogen-binding sites in eukaryotic glycogen synthase are required for high catalytic efficiency toward glycogen

Baskaran, S., Chikwana, V. M., Contreras, C. J., Davis, K. D., Wilson, W. A., De Paoli-Roach, A., Roach, P. & Hurley, T., Oct 30 2011, In : Journal of Biological Chemistry. 286, 39, p. 33999-34006 8 p.

Research output: Contribution to journalArticle

Glycogen Synthase
Glycogen
Binding Sites
Yeast
Mutation
73 Citations (Scopus)

Phosphate incorporation during glycogen synthesis and Lafora disease

Tagliabracci, V. S., Heiss, C., Karthik, C., Contreras, C. J., Glushka, J., Ishihara, M., Azadi, P., Hurley, T., De Paoli-Roach, A. & Roach, P., Mar 2 2011, In : Cell Metabolism. 13, 3, p. 274-282 9 p.

Research output: Contribution to journalArticle

Lafora Disease
Glycogen
Phosphates
Progressive Myoclonic Epilepsy
Uridine Diphosphate Glucose
63 Citations (Scopus)

PTG depletion removes lafora bodies and rescues the fatal epilepsy of lafora disease

Turnbull, J., De Paoli-Roach, A., Zhao, X., Cortez, M. A., Pencea, N., Tiberia, E., Piliguian, M., Roach, P., Wang, P., Ackerley, C. A. & Minassian, B. A., Apr 2011, In : PLoS Genetics. 7, 4, e1002037.

Research output: Contribution to journalArticle

Lafora Disease
epilepsy
Protein Phosphatase 1
Epilepsy
glycogen
1 Citation (Scopus)

Starch binding domain-containing protein 1/genethonin 1 is a novel participant in glycogen metabolism (Journal of Biological Chemistry (2010) 285, (34960-34971))

Jiang, S., Heller, B., Tagliabracci, V. S., Zhai, L., Irimia, J. M., De Paoli-Roach, A., Wells, C., Skurat, A. & Roach, P., Nov 11 2011, In : Journal of Biological Chemistry. 286, 45, p. 39673 1 p.

Research output: Contribution to journalArticle

Glycogen
Starch
Protein Domains
2010
19 Citations (Scopus)

Basis for MAP4 dephosphorylation-related microtubule network densification in pressure overload cardiac hypertrophy

Cheng, G., Takahashi, M., Shunmugavel, A., Wallenborn, J. G., De Paoli-Roach, A., Gergs, U., Neumann, J., Kuppuswamy, D., Menick, D. R. & Cooper IV, G., Dec 3 2010, In : Journal of Biological Chemistry. 285, 49, p. 38125-38140 16 p.

Research output: Contribution to journalArticle

Cardiomegaly
Densification
Microtubules
Protein Phosphatase 1
Pressure
76 Citations (Scopus)

Genetic depletion of the malin e3 ubiquitin ligase in mice leads to Lafora bodies and the accumulation of insoluble laforin

De Paoli-Roach, A., Tagliabracci, V. S., Segvich, D. M., Meyer, C. M., Irimia, J. M. & Roach, P., Aug 13 2010, In : Journal of Biological Chemistry. 285, 33, p. 25372-25381 10 p.

Research output: Contribution to journalArticle

Ubiquitin-Protein Ligases
Glycogen
Brain
Lafora Disease
Muscle
43 Citations (Scopus)

Impaired glucose tolerance and predisposition to the fasted state in liver glycogen synthase knock-out mice

Irimia, J. M., Meyer, C. M., Peper, C. L., Zhai, L., Bock, C. B., Previs, S. F., McGuinness, O. P., De Paoli-Roach, A. & Roach, P., Apr 23 2010, In : Journal of Biological Chemistry. 285, 17, p. 12851-12861 11 p.

Research output: Contribution to journalArticle

Glycogen Synthase
Liver Glycogen
Glucose Intolerance
Knockout Mice
Glucose
70 Citations (Scopus)

Starch binding domain-containing protein 1/genethonin 1 is a novel participant in glycogen metabolism

Jiang, S., Heller, B., Tagliabracci, V. S., Zhai, L., Irimia, J. M., De Paoli-Roach, A., Wells, C., Skurat, A. & Roach, P., Nov 5 2010, In : Journal of Biological Chemistry. 285, 45, p. 34960-34971 12 p.

Research output: Contribution to journalArticle

Glycogen
Metabolism
Starch
Proteins
Lysosomal-Associated Membrane Protein 1
48 Citations (Scopus)
Glycogen Synthase
Glucose-6-Phosphate
Phosphorylation
Enzymes
Inteins
2009
30 Citations (Scopus)

Phosphorylation of TPX2 by Plx1 enhances activation of Aurora A

Eckerdt, F., Pascreau, G., Phistry, M., Lewellyn, A. L., De Paoli-Roach, A. & Maller, J. L., Aug 1 2009, In : Cell Cycle. 8, 15, p. 2413-2419 7 p.

Research output: Contribution to journalArticle

Phosphorylation
Aurora Kinase A
Mitosis
Alanine
Oocytes
2008
114 Citations (Scopus)

Abnormal metabolism of glycogen phosphate as a cause for Lafora disease

Tagliabracci, V. S., Girard, J. M., Segvich, D., Meyer, C., Turnbull, J., Zhao, X., Minassian, B. A., De Paoli-Roach, A. & Roach, P., Dec 5 2008, In : Journal of Biological Chemistry. 283, 49, p. 33816-33825 10 p.

Research output: Contribution to journalArticle

Lafora Disease
Glycogen
Metabolism
Phosphates
Phosphorylation
23 Citations (Scopus)

A prevalent variant in PPP1R3A impairs glycogen synthesis and reduces muscle glycogen content in humans and mice

Savage, D. B., Zhai, L., Ravikumar, B., Cheol, S. C., Snaar, J. E., McGuire, A. C., Wou, S. E., Medina-Gomez, G., Kim, S., Bock, C. B., Segvich, D. M., Vidal-Puig, A., Wareham, N. J., Shulman, G. I., Karpe, F., Taylor, R., Pederson, B. A., Roach, P., O'Rahilly, S. & De Paoli-Roach, A., Jan 2008, In : PLoS Medicine. 5, 1, p. 113-122 10 p.

Research output: Contribution to journalArticle

Glycogen
Muscles
Glycogen Synthase
Mutation
Skeletal Muscle

Correction: A prevalent variant in PPP1R3A impairs glycogen synthesis and reduces muscle glycogen content in humans and mice

David, B. S., Zhai, L., Ravikumar, B., Choi, C. S., Snaar, J. E., McGuire, A. C., Wou, S. E., Medina-Gomez, G., Kim, S., Bock, C. B., Segvich, D. M., Solanky, B., Deelchand, D., Vidal-Puig, A., Wareham, N. J., Shulman, G. I., Karpe, F., Taylor, R., Pederson, B. A., Roach, P. & 2 others, O'Rahilly, S. & De Paoli-Roach, A., Dec 2008, In : PLoS Medicine. 5, 12, p. 1776 1 p.

Research output: Contribution to journalArticle

Glycogen
Muscle
Muscles
15 Citations (Scopus)

Inhibitor-2 prevents protein phosphatase 1-induced cardiac hypertrophy and mortality

Brüchert, N., Mavila, N., Boknik, P., Baba, H. A., Fabritz, L., Gergs, U., Kirchhefer, U., Kirchhof, P., Matus, M., Schmitz, W., De Paoli-Roach, A. & Neumann, J., Oct 2008, In : American Journal of Physiology - Heart and Circulatory Physiology. 295, 4

Research output: Contribution to journalArticle

Protein Phosphatase 1
Cardiomegaly
Mortality
Transgenic Mice
Heart Failure
2007
30 Citations (Scopus)

Glycogen metabolism in tissues from a mouse model of Lafora disease

Wang, W., Lohi, H., Skurat, A., De Paoli-Roach, A., Minassian, B. A. & Roach, P., Jan 15 2007, In : Archives of Biochemistry and Biophysics. 457, 2, p. 264-269 6 p.

Research output: Contribution to journalArticle

Lafora Disease
Glycogen
Metabolism
Glycogen Synthase
Enzyme activity
135 Citations (Scopus)

Laforin is a glycogen phosphatase, deficiency of which leads to elevated phosphorylation of glycogen in vivo

Tagliabracci, V. S., Turnbull, J., Wang, W., Girard, J. M., Zhao, X., Skurat, A., Delgado-Escueta, A. V., Minassian, B. A., De Paoli-Roach, A. & Roach, P., Dec 4 2007, In : Proceedings of the National Academy of Sciences of the United States of America. 104, 49, p. 19262-19266 5 p.

Research output: Contribution to journalArticle

Glycogen
Phosphoric Monoester Hydrolases
Phosphorylation
Lafora Disease
Phosphates
126 Citations (Scopus)

Structural basis for regulation of protein phosphatase 1 by inhibitor-2

Hurley, T., Yang, J., Zhang, L., Goodwin, K. D., Zou, Q., Cortese, M., Dunker, A. & De Paoli-Roach, A., Sep 28 2007, In : Journal of Biological Chemistry. 282, 39, p. 28874-28883 10 p.

Research output: Contribution to journalArticle

Protein Phosphatase 1
Phosphoprotein Phosphatases
Metal ions
Crystal structure
Amino Acids
2006
16 Citations (Scopus)

Relationship between glycogen accumulation and the laforin dual specificity phosphatase

Wang, W., Parker, G. E., Skurat, A., Raben, N., De Paoli-Roach, A. & Roach, P., Nov 24 2006, In : Biochemical and Biophysical Research Communications. 350, 3, p. 588-592 5 p.

Research output: Contribution to journalArticle

Dual-Specificity Phosphatases
Glycogen
Muscle
Muscles
Lafora Disease
85 Citations (Scopus)

Role of pyruvate dehydrogenase kinase isoenzyme 4 (PDHK4) in glucose homoeostasis during starvation

Jeoung, N. H., Wu, P., Joshi, M. A., Jaskiewicz, J., Bock, C. B., De Paoli-Roach, A. & Harris, R., Aug 1 2006, In : Biochemical Journal. 397, 3, p. 417-425 9 p.

Research output: Contribution to journalArticle

Starvation
Isoenzymes
Pyruvate Dehydrogenase Complex
Homeostasis
Glucose
2005
35 Citations (Scopus)

Control of mammalian glycogen synthase by PAS kinase

Wilson, W. A., Skurat, A., Probst, B., De Paoli-Roach, A., Roach, P. & Rutter, J., Nov 15 2005, In : Proceedings of the National Academy of Sciences of the United States of America. 102, 46, p. 16596-16601 6 p.

Research output: Contribution to journalArticle

Glycogen Synthase Kinases
Glycogen Synthase
Phosphorylation
Glycogen
Mammals
41 Citations (Scopus)

Enhanced cardiac function in mice overexpressing protein phosphatase Inhibitor-2

Kirchhefer, U., Baba, H. A., Bokník, P., Breeden, K. M., Mavila, N., Brüchert, N., Justus, I., Matus, M., Schmitz, W., De Paoli-Roach, A. & Neumann, J., Oct 1 2005, In : Cardiovascular Research. 68, 1, p. 98-108 11 p.

Research output: Contribution to journalArticle

Transgenic Mice
Protein Phosphatase 1
Cardiac Myocytes
Proteins
protein phosphatase inhibitor-2
172 Citations (Scopus)

Enhancement of cardiac function and suppression of heart failure progression by inhibition of protein phosphatase

Pathak, A., Del Monte, F., Zhao, W., Schultz, J. E., Lorenz, J. N., Bodi, I., Weiser, D., Hahn, H., Carr, A. N., Syed, F., Mavila, N., Jha, L., Qian, J., Marreez, Y., Chen, G., McGraw, D. W., Heist, E. K., Guerrero, J. L., De Paoli-Roach, A., Hajjar, R. J. & 1 others, Kranias, E. G., Apr 15 2005, In : Circulation Research. 96, 7, p. 756-766 11 p.

Research output: Contribution to journalArticle

Phosphoprotein Phosphatases
Heart Failure
Sarcoplasmic Reticulum
Calcium
Phosphoric Monoester Hydrolases
72 Citations (Scopus)

Exercise capacity of mice genetically lacking muscle glycogen synthase: In mice, muscle glycogen is not essential for exercise

Pederson, B. A., Cope, C. M., Schroeder, J. M., Smith, M. W., Irimia, J. M., Thurberg, B. L., De Paoli-Roach, A. & Roach, P., Apr 29 2005, In : Journal of Biological Chemistry. 280, 17, p. 17260-17265 6 p.

Research output: Contribution to journalArticle

Glycogen Synthase
Glycogen
Muscle
Muscles
Durability
75 Citations (Scopus)

Glucose metabolism in mice lacking muscle glycogen synthase

Pederson, B. A., Schroeder, J. M., Parker, G. E., Smith, M. W., De Paoli-Roach, A. & Roach, P., Dec 2005, In : Diabetes. 54, 12, p. 3466-3473 8 p.

Research output: Contribution to journalArticle

Glycogen Synthase
Glucose
Muscles
Glycogen
Serum
24 Citations (Scopus)

Mice with elevated muscle glycogen stores do not have improved exercise performance

Pederson, B. A., Cope, C. R., Irimia, J. M., Schroeder, J. M., Thurberg, B. L., De Paoli-Roach, A. & Roach, P., Jun 3 2005, In : Biochemical and Biophysical Research Communications. 331, 2, p. 491-496 6 p.

Research output: Contribution to journalArticle

Glycogen
Muscle
Muscles
Skeletal Muscle
Glycogen Synthase
2004
70 Citations (Scopus)

Abnormal cardiac development in the absence of heart glycogen

Pederson, B. A., Chen, H., Schroeder, J. M., Shou, W., De Paoli-Roach, A. & Roach, P., Aug 2004, In : Molecular and Cellular Biology. 24, 16, p. 7179-7187 9 p.

Research output: Contribution to journalArticle

Glycogen
Glycogen Synthase
Myocardium
Cardiac Edema
Glucose
34 Citations (Scopus)

A protein phosphatase-1γ1 isoform selectivity determinant in dendritic spine-associated neurabin

Carmody, L. C., Bauman, P. A., Bass, M. A., Mavila, N., De Paoli-Roach, A. & Colbran, R. J., May 21 2004, In : Journal of Biological Chemistry. 279, 21, p. 21714-21723 10 p.

Research output: Contribution to journalArticle

Dendritic Spines
Protein Phosphatase 1
Phosphoprotein Phosphatases
Protein Isoforms
Glutathione Transferase
440 Citations (Scopus)

PKC-α regulates cardiac contractility and propensity toward heart failure

Braz, J. C., Gregory, K., Pathak, A., Zhao, W., Sahin, B., Klevitsky, R., Kimball, T. F., Lorenz, J. N., Nairn, A. C., Liggett, S. B., Bodi, I., Wang, S., Schwartz, A., Lakatta, E. G., De Paoli-Roach, A., Robbins, J., Hewett, T. E., Bibb, J. A., Westfall, M. V., Kranias, E. G. & 1 others, Molkentin, J. D., Mar 2004, In : Nature Medicine. 10, 3, p. 248-254 7 p.

Research output: Contribution to journalArticle

Protein Kinase C
Heart Failure
Protein Phosphatase 1
Signal transduction
Sarcoplasmic Reticulum
2003
5 Citations (Scopus)

[2] Determination of Mammalian Glycogen Synthase Phosphatase Activity

De Paoli-Roach, A., Vilardo, P. G., Kim, J. H., Mavila, N., Vemuri, B. & Roach, P., 2003, In : Methods in Enzymology. 366, p. 17-34 18 p.

Research output: Contribution to journalArticle

Glycogen Synthase
Phosphoric Monoester Hydrolases
16 Citations (Scopus)

Insulin signaling inhibits the 5-HT2C receptor in choroid plexus via MAP kinase

Hurley, J., Zhang, S., Bye, L. S., Marshall, M. S., De Paoli-Roach, A., Guan, K., Fox, A. P. & Yu, L., Jun 9 2003, In : BMC Neuroscience. 4, 10.

Research output: Contribution to journalArticle

Receptor, Serotonin, 5-HT2C
Choroid Plexus
Mitogen-Activated Protein Kinases
G-Protein-Coupled Receptors
Insulin
17 Citations (Scopus)

Novel regulation of cardiac force-frequency relation by CREM (cAMP response element modulator)

Isoda, T., Paolocci, N., Haghighi, K., Wang, C., Wang, Y., Georgakopoulos, D., Servillo, G., Della Fazia, M. A., Kranias, E. G., De Paoli-Roach, A., Sassone-Corsi, P. & Kass, D. A., Feb 1 2003, In : FASEB Journal. 17, 2, p. 144-151 8 p.

Research output: Contribution to journalArticle

response elements
Response Elements
Modulators
Protein Phosphatase 1
phosphoprotein phosphatase
2002
158 Citations (Scopus)

Cyclin G2 associates with protein phosphatase 2A catalytic and regulatory B′ subunits in active complexes and induces nuclear aberrations and a G1/S phase cell cycle arrest

Bennin, D. A., Arachchige Don, A. S., Brake, T., McKenzie, J. L., Rosenbaum, H., Ortiz, L., De Paoli-Roach, A. & Horne, M. C., Jul 26 2002, In : Journal of Biological Chemistry. 277, 30, p. 27449-27467 19 p.

Research output: Contribution to journalArticle

Cyclin G2
Protein Phosphatase 2
G1 Phase
Cell Cycle Checkpoints
Aberrations
1 Citation (Scopus)
Phosphoprotein Phosphatases
Glycogen
Metabolism
Knockout Mice
Epinephrine
20 Citations (Scopus)

Reversal of diet-induced glucose intolerance by hepatic expression of a variant glycogen-targeting subunit of protein phosphatase-1

Gasa, R., Clark, C., Yang, R., De Paoli-Roach, A. & Newgard, C. B., Jan 11 2002, In : Journal of Biological Chemistry. 277, 2, p. 1524-1530 7 p.

Research output: Contribution to journalArticle

Protein Phosphatase 1
Glucose Intolerance
Nutrition
Glycogen
High Fat Diet