Bernardino Ghetti

  • 32255 Citations
  • 88 h-Index
1967 …2020

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1987

Dopamine D2 receptors increase in the dorsolateral striatum of weaver mutant mice

Kaseda, Y., Ghetti, B., Low, W. C., Richter, J. A. & Simon, J. R., Sep 29 1987, In : Brain research. 422, 1, p. 178-181 4 p.

Research output: Contribution to journalArticle

24 Scopus citations

Functional innervation of the striatum by ventral mesencephalic grafts in mice with inherited nigrostriatal dopamine deficiency

Low, W. C., Triarhou, L. C., Kaseda, Y., Norton, J. & Ghetti, B., Dec 1 1987, In : Brain research. 435, 1-2, p. 315-321 7 p.

Research output: Contribution to journalArticle

22 Scopus citations

Nerve cell atrophy and loss in the inferior olivary complex of “Purkinje cell degeneration” mutant mice

Ghetti, B., Norton, J. & Triarhou, L. C., Jun 15 1987, In : Journal of Comparative Neurology. 260, 3, p. 409-422 14 p.

Research output: Contribution to journalArticle

66 Scopus citations

Norepinephrine metabolism in the cerebellum of the purkinje cell degeneration (pcd) mutant mouse

Ghetti, B., Perry, K. W. & Fuller, R. W., 1987, In : Neurochemistry International. 10, 1, p. 39-47 9 p.

Research output: Contribution to journalArticle

11 Scopus citations

Selective loss of monoaminergic neurons in weaver mutant mice- an immunocytochemical study

Gupta, M., Felten, D. L. & Ghetti, B., Feb 3 1987, In : Brain research. 402, 2, p. 379-382 4 p.

Research output: Contribution to journalArticle

62 Scopus citations

Synaptic investment of striatal cellular domains by grafted dopamine neurons in weaver mutant mice

Triarhou, L. C., Low, W. C. & Ghetti, B., Dec 1 1987, In : Naturwissenschaften. 74, 12, p. 591-593 3 p.

Research output: Contribution to journalArticle

10 Scopus citations

Transplantation of cerebellar anlagen to hosts with genetic cerebellocortical atrophy

Triarhou, L. C., Low, W. C. & Ghetti, B., Jun 1 1987, In : Anatomy and Embryology. 176, 2, p. 145-154 10 p.

Research output: Contribution to journalArticle

19 Scopus citations
1988

Autoradiographic localization of insulin-like growth factor II receptors in cerebellar cortex of weaver and Purkinje cell degeneration mutant mice

Mendelsohn, L. G., Smith, M. C., Lucaites, V. L., Kerchner, G. A. & Ghetti, B., Aug 23 1988, In : Brain research. 458, 2, p. 361-366 6 p.

Research output: Contribution to journalArticle

6 Scopus citations

Changes in the content of glutamate and GABA in the cerebellar vermis and hemispheres of the Purkinje cell degeneration (pcd) mutant

McBride, W. J. & Ghetti, B., Feb 1 1988, In : Neurochemical Research. 13, 2, p. 121-125 5 p.

Research output: Contribution to journalArticle

10 Scopus citations

Layer-specific innervation of the dopamine-deficient frontal cortex in weaver mutant mice by grafted mesencephalic dopaminergic neurones

Triarhou, L. C., Low, W. C. & Ghetti, B., Oct 1 1988, In : Cell And Tissue Research. 254, 1, p. 11-15 5 p.

Research output: Contribution to journalArticle

6 Scopus citations

Mesencephalic dopamine cell deficit involves areas A8, A9 and A10 in weaver mutant mice

Triarhou, L. C., Norton, J. & Ghetti, B., Apr 1 1988, In : Experimental Brain Research. 70, 2, p. 256-265 10 p.

Research output: Contribution to journalArticle

152 Scopus citations

Progressive supranuclear palsy with hypertrophy of the olives - An immunocytochemical study of the cytoskeleton of argyrophilic neurons

Giaccone, G., Tagliavini, F., Street, J. S., Ghetti, B. & Bugiani, O., Jan 1 1988, In : Acta Neuropathologica. 77, 1, p. 14-20 7 p.

Research output: Contribution to journalArticle

19 Scopus citations

Reinstatement of synaptic connectivity in the striatum of weaver mutant mice following transplantation of ventral mesencephalic anlagen

Triarhou, L. C., Low, W. C., Norton, J. & Ghetti, B., Apr 1 1988, In : Journal of Neurocytology. 17, 2, p. 233-243 11 p.

Research output: Contribution to journalArticle

15 Scopus citations

Serotonin concentration and turnover in cerebelum and other brain regions of pcd mutant mice

Ghetti, B., Perry, K. W. & Fuller, R. W., Aug 23 1988, In : Brain research. 458, 2, p. 367-371 5 p.

Research output: Contribution to journalArticle

15 Scopus citations

Synaptic connectivity of tyrosine hydroxylase immunoreactive nerve terminals in the striatum of normal, heterozygous and homozygous weaver mutant mice

Triarhou, L. C., Norton, J. & Ghetti, B., Apr 1 1988, In : Journal of Neurocytology. 17, 2, p. 221-232 12 p.

Research output: Contribution to journalArticle

26 Scopus citations
1989

Alzheimer patients: preamyloid deposits are more widely distributed than senile plaques throughout the central nervous system

Bugiani, O., Giaccone, G., Frangione, B., Ghetti, B. & Tagliavini, F., Sep 11 1989, In : Neuroscience Letters. 103, 3, p. 263-268 6 p.

Research output: Contribution to journalArticle

49 Scopus citations

Degeneration and graft-induced restoration of dopamine innervation in the weaver mouse neostriatum: a quantitative radioautographic study of [3H]dopamine uptake

Doucet, G., Brundin, P., Seth, S., Murata, Y., Strecker, R. E., Triarhou, L. C., Ghetti, B. & Björklund, A., Oct 1 1989, In : Experimental Brain Research. 77, 3, p. 552-568 17 p.

Research output: Contribution to journalArticle

44 Scopus citations

Developmental expression of polypeptide PEP-19 in cerebellar cell suspensions transplanted into the cerebellum of pcd mutant mice

Chang, A. C., Triarhou, L. C., Alyea, C. J., Low, W. C. & Ghetti, B., Aug 1 1989, In : Experimental Brain Research. 76, 3, p. 639-645 7 p.

Research output: Contribution to journalArticle

17 Scopus citations

Gerstmann-straussler-scheinker disease. I. extending the clinical spectrum

Farlow, M. R., Yee, R. D., Dlouhy, S. R., Conneally, P. M., Azzarelli, B. & Ghetti, B., Nov 1989, In : Neurology. 39, 11, p. 1446-1452 7 p.

Research output: Contribution to journalArticle

79 Scopus citations

Gerstmann-sträussler-scheinker disease. II. Neurofibrillary tangles and plaques with PrP-amyloid coexist in an affected family

Ghetti, B., Tagliavini, F., Masters, C. L., Beyreuther, K., Ciaccone, G., Verga, L., Farlow, M. R., Conneally, P. M., Dlouhy, S. R., Azzarelli, B. & Bugiani, O., Nov 1989, In : Neurology. 39, 11, p. 1453-1461 9 p.

Research output: Contribution to journalArticle

155 Scopus citations

The dendritic dopamine projection of the substantia nigra: phenotypic denominator of weaver gene action in hetero- and homozygosity

Triarhou, L. C. & Ghetti, B., Nov 6 1989, In : Brain research. 501, 2, p. 373-381 9 p.

Research output: Contribution to journalArticle

33 Scopus citations
1990

Age-related changes in striatal dopamine D2 receptor binding in weaver mice and effects of ventral mesencephalic grafts

Kaseda, Y., Ghetti, B., Low, W. C., Norton, J., Brittain, H., Triarhou, L. C., Richter, J. A. & Simon, J. R., Dec 1 1990, In : Experimental Brain Research. 83, 1, p. 1-8 8 p.

Research output: Contribution to journalArticle

17 Scopus citations

Alzheimer patients and Down patients: Abnormal presynaptic terminals are related to cerebral preamyloid deposits

Bugiani, O., Giaccone, G., Verga, L., Pollo, B., Ghetti, B., Frangione, B. & Tagliavini, F., Oct 30 1990, In : Neuroscience Letters. 119, 1, p. 56-59 4 p.

Research output: Contribution to journalArticle

46 Scopus citations

Chapter 21 Dopamine neurone grafting to the weaver mouse neostriatum

Triarhou, L. C., Low, W. C. & Ghetti, B., Jan 1 1990, In : Progress in Brain Research. 82, C, p. 187-195 9 p.

Research output: Contribution to journalArticle

5 Scopus citations

Chapter 22 Timing of neuronal replacement in cerebellar degenerative ataxia of Purkinje cell type

Ghetti, B., Triarhou, L. C., Alyea, C. J., Low, W. C. & Chang, A. C., Jan 1 1990, In : Progress in Brain Research. 82, C, p. 197-202 6 p.

Research output: Contribution to journalArticle

6 Scopus citations

Intrastriatal implants of mesencephalic cell suspensions in weaver mutant mice: ultrastructural relationships of dopaminergic dendrites and axons issued from the graft

Triarhou, L. C., Brundin, P., Doucet, G., Norton, J., Björklund, A. & Ghetti, B., Jan 1 1990, In : Experimental Brain Research. 79, 1, p. 3-17 15 p.

Research output: Contribution to journalArticle

18 Scopus citations

Neurofibrillary tangles of the Indiana kindred of Gerstmann-Sträussler-Scheinker disease share antigenic determinants with those of Alzheimer disease

Giaccone, G., Tagliavini, F., Verga, L., Frangione, B., Farlow, M. R., Bugiani, O. & Ghetti, B., Oct 22 1990, In : Brain research. 530, 2, p. 325-329 5 p.

Research output: Contribution to journalArticle

51 Scopus citations
1991

A mutation in the amyloid precursor protein associated with hereditary Alzheimer's disease

Murrell, J., Farlow, M., Ghetti, B. & Benson, M. D., Jan 1 1991, In : Science. 254, 5028, p. 97-99 3 p.

Research output: Contribution to journalArticle

883 Scopus citations

Amyloid protein of Gerstmann-Straussler-Scheinker disease (Indiana kindred) is an 11 kd fragment of prion protein with an N-terminal glycine at codon 58

Tagliavini, F., Prelli, F., Ghiso, J., Bugiani, O., Serban, D., Prusiner, S. B., Farlow, M. R., Ghetti, B. & Frangione, B., Mar 18 1991, In : EMBO Journal. 10, 3, p. 513-519 7 p.

Research output: Contribution to journalArticle

164 Scopus citations

Asymmetrical cerebral atrophy in Alzheimer's disease

Bugiani, O., Constantinidis, J., Ghetti, B., Bouras, C. & Tagliavini, F., Jan 1 1991, In : Clinical Neuropathology. 10, 2, p. 55-60 6 p.

Research output: Contribution to journalArticle

18 Scopus citations

In Vitro Release of Endogenous Dopamine from the Striatum of the Weaver Mutant Mouse

Simon, J. R., Yu, H., Richter, J. A., Vasko, M. R. & Ghetti, B., Nov 1991, In : Journal of Neurochemistry. 57, 5, p. 1478-1482 5 p.

Research output: Contribution to journalArticle

12 Scopus citations

Serotonin-immunoreactivity in the cerebellum of two neurological mutant mice and the corresponding wild-type genetic stocks

Triarhou, L. C. & Ghetti, B., Jan 1 1991, In : Journal of chemical neuroanatomy. 4, 6, p. 421-428 8 p.

Research output: Contribution to journalArticle

18 Scopus citations

Stabilisation of neurone number in the inferior olivary complex of aged 'Purkinje cell degeneration' mutant mice

Triarhou, L. C. & Ghetti, B., May 1 1991, In : Acta Neuropathologica. 81, 6, p. 597-602 6 p.

Research output: Contribution to journalArticle

26 Scopus citations

Unique cerebellar phenotype combining granule and Purkinje cell loss: Morphological evidence for weaver*pcd double mutant mice

Ghetti, B., Triarhou, L. C., Alyea, C. J., Dlouhy, S. R. & Karn, R. C., Jan 1 1991, In : Journal of Neurocytology. 20, 1, p. 27-38 12 p.

Research output: Contribution to journalArticle

6 Scopus citations
1992

Abnormal Eye Movements in Gerstmann-Sträussler-Scheinker Disease

Yee, R. D., Farlow, M. R., Suzuki, D. A., Betelak, K. F. & Ghetti, B., Jan 1992, In : Archives of Ophthalmology. 110, 1, p. 68-74 7 p.

Research output: Contribution to journalArticle

15 Scopus citations

Comparison of alterations in tyrosine hydroxylase, dopamine levels, and dopamine uptake in the striatum of the weaver mutant mouse

Richter, J. A., Stotz, E. H., Ghetti, B. & Simon, J. R., May 1 1992, In : Neurochemical Research. 17, 5, p. 437-441 5 p.

Research output: Contribution to journalArticle

26 Scopus citations

Degeneration of mesencephalic dopamine neurons in weaver mutant mice

Ghetti, B. & Triarhou, L. C., Mar 1992, In : Neurochemistry International. 20, SUPPL., p. 305-307 3 p.

Research output: Contribution to journalArticle

23 Scopus citations
1 Scopus citations
23 Scopus citations

Linkage of the Indiana kindred of gerstmann-sträussler-scheinker disease to the prion protein gene

Dlouhy, S. R., Hsiao, K., Farlow, M. R., Foroud, T., Conneally, P. M., Johnson, P., Prusiner, S. B., Hodes, M. E. & Ghetti, B., Apr 1992, In : Nature genetics. 1, 1, p. 64-67 4 p.

Research output: Contribution to journalArticle

176 Scopus citations

Low cerebrospinal-fluid concentrations of soluble amyloid β-protein precursor in hereditary Alzheimer's disease

Farlow, M., Ghetti, B., Benson, M. D., van Nostrand, W. E., Farrow, J. S. & Wagner, S. L., Aug 22 1992, In : The Lancet. 340, 8817, p. 453-454 2 p.

Research output: Contribution to journalArticle

54 Scopus citations

Mutant prion proteins in gerstmann-sträussler-scheinker disease with neurofibrillary tangles

Hsiao, K., Dlouhy, S. R., Farlow, M. R., Cass, C., Da Costa, M., Conneally, P. M., Hodes, M. E., Ghetti, B. & Prusiner, S. B., Apr 1992, In : Nature genetics. 1, 1, p. 68-71 4 p.

Research output: Contribution to journalArticle

204 Scopus citations

Prion protein preamyloid and amyloid deposits in Gerstmann-Sträussler-Scheinker disease, Indiana kindred

Giaccone, G., Verga, L., Bugiani, O., Frangione, B., Serban, D., Prusiner, S. B., Farlow, M. R., Ghetti, B. & Tagliavini, F., Oct 1 1992, In : Proceedings of the National Academy of Sciences of the United States of America. 89, 19, p. 9349-9353 5 p.

Research output: Contribution to journalArticle

Open Access
79 Scopus citations

Serotonin fiber innervation of cerebellar cell suspensions intraparenchymally grafted to the cerebellum of pcd mutant mice

Triarhou, L. C., Low, W. C. & Ghetti, B., May 1 1992, In : Neurochemical Research. 17, 5, p. 475-482 8 p.

Research output: Contribution to journalArticle

9 Scopus citations
23 Scopus citations
13 Scopus citations
1993

A68 is a component of paired helical filaments of Gerstmann-Sträussler-Scheinker disease, Indiana kindred

Tagliavini, F., Giaccone, G., Prelli, F., Verga, L., Porro, M., Trojanowski, J. Q., Farlow, M. R., Frangione, B., Ghetti, B. & Bugiani, O., Jul 9 1993, In : Brain research. 616, 1-2, p. 325-329 5 p.

Research output: Contribution to journalArticle

40 Scopus citations
4 Scopus citations

Characterization of amyloid familial β-peptide in familial alzheimer′s disease with APP717 mutations

Liepnieks, J. J., Ghetti, B., Farlow, M., Roses, A. D. & Benson, M. D., Dec 15 1993, In : Biochemical and Biophysical Research Communications. 197, 2, p. 386-392 7 p.

Research output: Contribution to journalArticle

11 Scopus citations

Dopamine-depleting effects of MPTP and reserpine in weaver mutant mice

Richter, J. A., Ghetti, B. & Simon, J. R., Dec 1 1993, In : Molecular and Chemical Neuropathology. 20, 3, p. 219-228 10 p.

Research output: Contribution to journalArticle

2 Scopus citations