Bernardino Ghetti

  • 32255 Citations
  • 88 h-Index
1967 …2020

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1993

Embryonic cerebellar graft development during acute phase of gliosis in the cerebellum of pcd mutant mice.

Chang, A. C. & Ghetti, B., 1993, In : The Chinese journal of physiology. 36, 3, p. 141-149 9 p.

Research output: Contribution to journalArticle

4 Scopus citations

Hypospermatogenesis is the cause of infertility in the Male weaver mutant mouse

Vogelweid, C. M., Verina, T., Norton, J., Harruff, R. & Ghetti, B., Jan 1 1993, In : Journal of Neurogenetics. 9, 2, p. 89-104 16 p.

Research output: Contribution to journalArticle

23 Scopus citations

Is there a significant somatodendritic uptake of dopamine in the substantia nigra? Evidence from the weaver mutant mouse

Simon, J. R. & Ghetti, B., May 1993, In : Neurochemistry International. 22, 5, p. 471-477 7 p.

Research output: Contribution to journalArticle

11 Scopus citations
7 Scopus citations
8 Scopus citations

RFLP analysis for APP 717 mutations associated with Alzheimer's disease

Zeldenrust, S. R., Murrell, J., Farlow, M., Ghetti, B., Roses, A. D. & Benson, M. D., Jan 1 1993, In : Journal of Medical Genetics. 30, 6, p. 476-478 3 p.

Research output: Contribution to journalArticle

7 Scopus citations

Serotonin content is elevated in the dopamine deficient striatum of the weaver mutant mouse

Stotz, E. H., Triarhou, L. C., Ghetti, B. & Simon, J. R., Mar 26 1993, In : Brain research. 606, 2, p. 267-272 6 p.

Research output: Contribution to journalArticle

17 Scopus citations

Synthetic peptides homologous to prion protein residues 106-147 form amyloid-like fibrils in vitro

Tagliavini, F., Prelli, F., Verga, L., Giaccone, G., Sarma, R., Gorevic, P., Ghetti, B., Passerini, F., Ghibaudi, E., Forloni, G., Salmona, M., Bugiani, O. & Frangione, B., Oct 15 1993, In : Proceedings of the National Academy of Sciences of the United States of America. 90, 20, p. 9678-9682 5 p.

Research output: Contribution to journalArticle

Open Access
226 Scopus citations

βPP participates in PrP-amyloid plaques of gerstmann-sträussler-scheinker disease, Indiana kindred

Bugiani, O., Giaccone, G., Verga, L., Pollo, B., Frangione, B., Farlow, M. R., Tagliavini, F. & Ghetti, B., Jan 1993, In : Journal of Neuropathology and Experimental Neurology. 52, 1, p. 64-70 7 p.

Research output: Contribution to journalArticle

51 Scopus citations
1994

Age-dependent alterations in dopamine content, tyrosine hydroxylase activity, and dopamine uptake in the striatum of the weaver mutant mouse

Simon, J. R., Richter, J. A. & Ghetti, B., Feb 1 1994, In : Journal of Neurochemistry. 62, 2, p. 543-548 6 p.

Research output: Contribution to journalArticle

19 Scopus citations

Alterations in dopamine and serotonin uptake systems in the striatum of the weaver mutant mouse

Stotz, E. H., Palacios, J. M., Landwehrmeyer, B., Norton, J., Ghetti, B., Simon, J. R. & Triarhou, L. C., Feb 1 1994, In : Journal of Neural Transmission. 97, 1, p. 51-64 14 p.

Research output: Contribution to journalArticle

16 Scopus citations

Amyloid fibrils in Gerstmann-Sträussler-Scheinker disease (Indiana and Swedish Kindreds) express only PrP peptides encoded by the mutant allele

Tagliavini, F., Prelli, F., Porro, M., Rossi, G., Giaccone, G., Farlow, M. R., Dlouhy, S. R., Ghetti, B., Bugiani, O. & Frangione, B., Nov 18 1994, In : Cell. 79, 4, p. 695-703 9 p.

Research output: Contribution to journalArticle

130 Scopus citations
8 Scopus citations

cDNA approaches to isolation of the mouse mutant weaver gene

Hodes, M. E., Dlouhy, S. R., Wei, J. J., Wang, Y., Sangameswaran, L., Lazar, V., Triarhou, L. C. & Ghetti, B., Nov 1 1994, In : Neurochemical Research. 19, 11, p. 1359-1362 4 p.

Research output: Contribution to journalArticle

1 Scopus citations

Cerebrospinal fluid levels of amyloid β-protein precursor are low in gerstmann-sträussler-scheinker disease, Indiana kindred

Farlow, M. R., Ghetti, B., Dlouhy, S., Giaccone, G., Bugiani, O., Tagliavini, F. & Wagner, S., Aug 1994, In : Neurology. 44, 8, p. 1508-1510 3 p.

Research output: Contribution to journalArticle

3 Scopus citations
26 Scopus citations

Correlated quantitative studies of the neostriatum, nucleus accumbens, substantia nigra, and ventral tegmental area in normal and weaver mutant mice

Bayer, S. A., Triarhou, L. C., Thomas, J. D. & Ghetti, B., Jan 1 1994, In : Journal of Neuroscience. 14, 11 II, p. 6901-6910 10 p.

Research output: Contribution to journalArticle

Open Access
18 Scopus citations

Familial Gerstmann-Sträussler-Scheinker disease with neurofibrillary tangles

Ghetti, B., Tagliavini, F., Giaccone, G., Bugiani, O., Frangione, B., Farlow, M. R. & Dlouhy, S. R., Feb 1 1994, In : Molecular Neurobiology. 8, 1, p. 41-48 8 p.

Research output: Contribution to journalArticle

63 Scopus citations

Fatal familial insomnia and familial Creutzfeldt-Jakob disease: Different prion proteins determined by a DNA polymorphism

Monari, L., Chen, S. G., Brown, P., Parchi, P., Petersen, R. B., Mikol, J., Gray, F., Cortelli, P., Montagna, P., Ghetti, B., Goldfarb, L. G., Gajdusek, D. C., Lugaresi, E., Gambetti, P. & Autilio-Gambetti, L., Mar 29 1994, In : Proceedings of the National Academy of Sciences of the United States of America. 91, 7, p. 2839-2842 4 p.

Research output: Contribution to journalArticle

Open Access
250 Scopus citations

Molecular characterization of a novel cDNA from murine cerebellum, developmental expression, and distribution in brain

Kambouris, M., Sangameswaran, L., Triarhou, L. C., Kozak, C. A., Dlouhy, S. R., Ghetti, B. & Hodes, M. E., Sep 1994, In : Molecular Brain Research. 25, 3-4, p. 192-199 8 p.

Research output: Contribution to journalArticle

2 Scopus citations

Novel cDNA clones obtained by antibody screening of a mouse cerebellar cDNA expression library

Kambouris, M., Triarhou, L. C., Dlouhy, S. R., Sangameswaran, L., Luo, F., Ghetti, B. & Hodes, M. E., Sep 1994, In : Molecular Brain Research. 25, 3-4, p. 183-191 9 p.

Research output: Contribution to journalArticle

6 Scopus citations

Studies on the striatal dopamine uptake system of weaver mutant mice and effects of ventral mesencephalic grafts

Triarhou, L. C., Stotz, E. H., Low, W. C., Norton, J., Ghetti, B., Landwehrmeyer, B., Palacios, J. M. & Simon, J. R., Nov 1 1994, In : Neurochemical Research. 19, 11, p. 1349-1358 10 p.

Research output: Contribution to journalArticle

3 Scopus citations

The weaver mutant mouse as a model of nigrostriatal dysfunction

Simon, J. R. & Ghetti, B., Aug 1 1994, In : Molecular Neurobiology. 9, 1-3, p. 183-189 7 p.

Research output: Contribution to journalArticle

21 Scopus citations
1995

Altered IGFBP5 gene expression in the cerebellar external germinal layer of weaver mutant mice

Lee, W. H., Wang, G. M., Lo, T., Triarhou, L. C. & Ghetti, B., Jun 1995, In : Molecular Brain Research. 30, 2, p. 259-268 10 p.

Research output: Contribution to journalArticle

20 Scopus citations

Degeneration of sertoli and spermatogenic cells in homozygous and heterozygous weaver mice

Verina, T., Tang, X., Fitzpatrick, L., Norton, J., Vogelweid, C. & Ghetti, B., Jan 1 1995, In : Journal of Neurogenetics. 9, 4, p. 251-265 15 p.

Research output: Contribution to journalArticle

17 Scopus citations

Detection of apoptosis in weaver cerebellum by electron microscopic in situ end-labeling of fragmented DNA

Migheli, A., Attanasio, A., Lee, W. H., Bayer, S. A. & Ghetti, B., Oct 13 1995, In : Neuroscience Letters. 199, 1, p. 53-56 4 p.

Research output: Contribution to journalArticle

51 Scopus citations

Dopaminergic parameters in the striatum and substantia nigra of seven strains of mice: Higher density in striatum of CAST compared to BALB mice

Richter, J. A., Brenneman, M. G., Dlouhy, S. R. & Ghetti, B., Apr 1 1995, In : Neurochemical Research. 20, 4, p. 395-400 6 p.

Research output: Contribution to journalArticle

1 Scopus citations

Dopamine Transporter‐Dependent and ‐Independent Endogenous Dopamine Release from Weaver Mouse Striatum In Vitro

Richter, J. A., Bare, D. J., Yu, H., Ghetti, B. & Simon, J. R., Jan 1995, In : Journal of Neurochemistry. 64, 1, p. 191-198 8 p.

Research output: Contribution to journalArticle

11 Scopus citations

Endogenous serotonin release from the dopamine-deficient striatum of the weaver mutant mouse

Stotz-Potter, E. H., Ghetti, B. & Simon, J. R., Jul 1 1995, In : Neurochemical Research. 20, 7, p. 821-826 6 p.

Research output: Contribution to journalArticle

1 Scopus citations

Gerstmann-straussler-scheinker disease (Prnp p102l): Amyloid deposits are best recognized by antibodies directed to epitopes in prp region 90-165

Piccardo, P., Ghetti, B., Dickson, D. W., Vinters, H. V., Giaccone, G., Bugiani, O., Tagliavini, F., Young, K., Dlouhy, S. R., Seiler, C., Jones, C. K., Lazzarini, A., Golbe, L. I., Zimmerman, T. R., Perlman, S. L., McLachlan, D. C., George-Hyslop, P. H. S. & Lennox, A., Nov 1995, In : Journal of Neuropathology and Experimental Neurology. 54, 6, p. 790-801 12 p.

Research output: Contribution to journalArticle

36 Scopus citations

Gerstmann‐Sträussler‐Scheinker Disease and the Indiana Kindred

Ghetti, B., Dlouhy, S. R., Giaccone, G., Bugiani, O., Frangione, B., Farlow, M. R. & Tagliavini, F., Jan 1995, In : Brain Pathology. 5, 1, p. 61-75 15 p.

Research output: Contribution to journalArticle

142 Scopus citations

Gerstmann-straussler-scheinker disease with mutation at codon 102 and methionine at codon 129 of prnp in previously unreported patients

Young, K., Jones, C. K., Piccardo, P., Lazzarini, A., Golbe, L. I., Zimmerman, T. R., Dickson, D. W., McLachlan, D. W., St George-Hyslop, P., Lennox, A., Perlman, S., Vinters, H. V., Hodes, M. E., Dlouhy, S. & Ghetti, B., Jun 1995, In : Neurology. 45, 6, p. 1127-1134 8 p.

Research output: Contribution to journalArticle

46 Scopus citations

Neurofibrillary tangles in Niemann-Pick disease type C

Suzuki, K., Parker, C. C., Pentchev, P. G., Katz, D., Ghetti, B., D'Agostino, A. N. & Carstea, E. D., Mar 1 1995, In : Acta Neuropathologica. 89, 3, p. 227-238 12 p.

Research output: Contribution to journalArticle

151 Scopus citations

Selective vulnerability of late-generated dopaminergic neurons of the substantia nigra in weaver mutant mice

Bayer, S. A., Wills, K. V., Triarhou, L. C., Verina, T., Thomas, J. D. & Ghetti, B., Sep 26 1995, In : Proceedings of the National Academy of Sciences of the United States of America. 92, 20, p. 9137-9140 4 p.

Research output: Contribution to journalArticle

38 Scopus citations

Systematic differences in time of dopaminergic neuron origin between normal mice and homozygous weaver mutants

Bayer, S. A., Wills, K. V., Triarhou, L. C., Thomas, J. D. & Ghetti, B., Aug 1 1995, In : Experimental Brain Research. 105, 2, p. 200-208 9 p.

Research output: Contribution to journalArticle

22 Scopus citations

The Tyrosine Kinase Inhibitor Genistein Increases Endogenous Dopamine Release from Normal and Weaver Mutant Mouse Striatal Slices

Bare, D. J., Ghetti, B. & Richter, J. A., Nov 1995, In : Journal of Neurochemistry. 65, 5, p. 2096-2104 9 p.

Research output: Contribution to journalArticle

6 Scopus citations

Time of neuron origin and gradients of neurogenesis in midbrain dopaminergic neurons in the mouse

Bayer, S. A., Wills, K. V., Triarhou, L. C. & Ghetti, B., Aug 1 1995, In : Experimental Brain Research. 105, 2, p. 191-199 9 p.

Research output: Contribution to journalArticle

131 Scopus citations

Ventral mesencephalic grafts in the neostriatum of the weaver mutant mouse: Structural molecule and receptor studies

Triarhou, L. C., Solà, C., Mengod, G., Garcia-Ladona, F. J., Landwehrmeyer, B., Ghetti, B. & Palacios, J. M., Jan 1 1995, In : Cell Transplantation. 4, 1, p. 39-48 10 p.

Research output: Contribution to journalArticle

4 Scopus citations
1996

Cloning a cDNA for carbonyl reductase (Cbr) from mouse cerebellum: Murine genes that express Cbr map to chromosomes 16 and 11

Jianjun, W., Dlouhy, S. R., Hara, A., Ghetti, B. & Hodes, M. E., May 15 1996, In : Genomics. 34, 1, p. 147-148 2 p.

Research output: Contribution to journalArticle

18 Scopus citations

Direct cDNA selection with DNA microdissected from mouse chromosome 16: Isolation of novel clones and construction of a partial transcription map of the C3-C4 region

Wei, J., Hodes, M. E., Wang, Y., Feng, Y., Ghetti, B. & Dlouhy, S. R., Aug 1996, In : Genome research. 6, 8, p. 678-687 10 p.

Research output: Contribution to journalArticle

Open Access
8 Scopus citations

Familial and sporadic Alzheimer's disease: Neuropathology cannot exclude a final common pathway

Lippa, C. F., Saunders, A. M., Smith, T. W., Swearer, J. M., Drachman, D. A., Ghetti, B., Nee, L., Pulaski-Salo, D., Dickson, D., Robitaille, Y., Bergeron, C., Crain, B., Benson, M. D., Farlow, M., Hyman, B. T., St. George-Hyslop, P., Roses, A. D. & Pollen, D. A., Feb 1996, In : Neurology. 46, 2, p. 406-412 7 p.

Research output: Contribution to journalArticle

90 Scopus citations

Linkage mapping of microdissected clones from distal mouse chromosome 16

Wei, J., Dlouhy, S. R., Wang, Y., Zhu, J., Fitzpatrick, L., Ghetti, B. & Hodes, M. E., May 1 1996, In : Somatic Cell and Molecular Genetics. 22, 3, p. 227-232 6 p.

Research output: Contribution to journalArticle

3 Scopus citations

Molecular basis of phenotypic variability in sporadic Creutzfeldt-Jakob disease

Parchi, P., Castellani, R., Capellari, S., Ghetti, B., Young, K., Chen, S. G., Farlow, M., Dickson, D. W., Sima, A. A. F., Trojanowski, J. Q., Petersen, R. B. & Gambetti, P., Jun 1 1996, In : Annals of neurology. 39, 6, p. 767-778 12 p.

Research output: Contribution to journalArticle

660 Scopus citations

Phenotypic effects of the weaver gene are evident in the embryonic cerebellum but not in the ventral midbrain

Bayer, S. A., Wills, K. V., Wei, J., Feng, Y., Dlouhy, S. R., Hodes, M. E., Verina, T. & Ghetti, B., Oct 23 1996, In : Developmental Brain Research. 96, 1-2, p. 130-137 8 p.

Research output: Contribution to journalArticle

23 Scopus citations

Proteinase-K-resistant prion protein isoforms in Gerstmann-Straussler- Scheinker disease (Indiana kindred)

Piccardo, P., Seiler, C., Dlouhy, S. R., Young, K., Farlow, M. R., Prelli, F., Frangione, B., Bugiani, O., Tagliavini, F. & Ghetti, B., Nov 1996, In : Journal of Neuropathology and Experimental Neurology. 55, 11, p. 1157-1163 7 p.

Research output: Contribution to journalArticle

Open Access
45 Scopus citations

PRP27-30 is a normal soluble prion protein fragment released by human platelets

Perini, F., Vidal, R., Ghetti, B., Tagliavini, F., Frangione, B. & Prelli, F., Jun 25 1996, In : Biochemical and Biophysical Research Communications. 223, 3, p. 572-577 6 p.

Research output: Contribution to journalArticle

69 Scopus citations

The weaver mutation changes the ion selectivity of the affected inwardly rectifying potassium channel GIRK2

Tong, Y., Wei, J., Zhang, S., Strong, J. A., Dlouhy, S. R., Hodes, M. E., Ghetti, B. & Yu, L., Jul 15 1996, In : FEBS Letters. 390, 1, p. 63-68 6 p.

Research output: Contribution to journalArticle

47 Scopus citations

Vascular variant of prion protein cerebral amyloidosis with τ-positive neurofibrillary tangles: The phenotype of the stop codon 145 mutation in PRNP

Ghetti, B., Piccardo, P., Spillantini, M. G., Ichimiya, Y., Porro, M., Perini, F., Kitamoto, T., Tateishi, J., Seiler, C., Frangione, B., Bugiani, O., Giaccone, G., Prelli, F., Goedert, M., Dlouhy, S. R. & Tagliavini, F., Jan 23 1996, In : Proceedings of the National Academy of Sciences of the United States of America. 93, 2, p. 744-748 5 p.

Research output: Contribution to journalArticle

232 Scopus citations
1997

A possible role for tyrosine kinases in the regulation of the neuronal dopamine transporter in mouse striatum

Simon, J. R., Bare, D. J., Ghetti, B. & Richter, J. A., Apr 10 1997, In : Neuroscience Letters. 224, 3, p. 201-205 5 p.

Research output: Contribution to journalArticle

33 Scopus citations

Atrophy and loss of dopaminergic mesencephalic neurons in heterozygous weaver mice

Verina, T., Norton, J. A., Sorbel, J. J., Triarhou, L. C., Laferty, D., Richter, J. A., Simon, J. R. & Ghetti, B., Jan 30 1997, In : Experimental Brain Research. 113, 1, p. 5-12 8 p.

Research output: Contribution to journalArticle

14 Scopus citations