Bernardino Ghetti

  • 30504 Citations
  • 85 h-Index
1967 …2021
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Publications 1967 2019

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2009
3 Citations (Scopus)

Regional differences in the vulnerability of substantia nigra dopaminergic neurons in weaver mice

Martí, J., Santa-Cruz, M. C., Molina, V., Serra, R., Bayer, S. A., Ghetti, B. & Hervás, J. P., 2009, In : Acta Neurobiologiae Experimentalis. 69, 2, p. 198-206 9 p.

Research output: Contribution to journalArticle

Neurologic Mutant Mice
Dopaminergic Neurons
Substantia Nigra
Cell Death
Tyrosine 3-Monooxygenase
127 Citations (Scopus)

TARDBP variation associated with frontotemporal dementia, supranuclear gaze palsy, and chorea

Kovacs, G. G., Murrell, J. R., Horvath, S., Haraszti, L., Majtenyi, K., Molnar, M. J., Budka, H., Ghetti, B. & Spina, S., Sep 15 2009, In : Movement Disorders. 24, 12, p. 1843-1847 5 p.

Research output: Contribution to journalArticle

Frontotemporal Dementia
Chorea
Amyotrophic Lateral Sclerosis
Paralysis
Frontotemporal Lobar Degeneration
2008
51 Citations (Scopus)

Aggregated, wild-type prion protein causes neurological dysfunction and synaptic abnormalities

Chiesa, R., Piccardo, P., Biasini, E., Ghetti, B. & Harris, D. A., Dec 3 2008, In : Journal of Neuroscience. 28, 49, p. 13258-13267 10 p.

Research output: Contribution to journalArticle

Prion Diseases
Presynaptic Terminals
Tremor
Paresis
Transgenes
79 Citations (Scopus)

Analysis of tau phosphorylation and truncation in a mouse model of human tauopathy

Delobel, P., Lavenir, I., Fraser, G., Ingram, E., Holzer, M., Ghetti, B., Spillantini, M. G., Crowther, R. A. & Goedert, M., Jan 2008, In : American Journal of Pathology. 172, 1, p. 123-131 9 p.

Research output: Contribution to journalArticle

Tauopathies
Phosphorylation
Transgenic Mice
Spinal Cord
Alzheimer Disease
62 Citations (Scopus)

Characterization of truncated forms of abnormal prion protein in Creutzfeldt-Jakob disease

Notari, S., Strammiello, R., Capellari, S., Giese, A., Cescatti, M., Grassi, J., Ghetti, B., Langeveld, J. P. M., Zou, W. Q., Gambetti, P., Kretzschmar, H. A. & Parchi, P., Nov 7 2008, In : Journal of Biological Chemistry. 283, 45, p. 30557-30565 9 p.

Research output: Contribution to journalArticle

Creutzfeldt-Jakob Syndrome
Prion Diseases
Digestion
Peptide Hydrolases
Epitope Mapping
28 Citations (Scopus)

Detection of filamentous tau inclusions by the fluorescent Congo red derivative FSB [(trans,trans)-1-fluoro-2,5-bis(3-hydroxycarbonyl-4-hydroxy)styrylbenzene]

Velasco, A., Fraser, G., Delobel, P., Ghetti, B., Lavenir, I. & Goedert, M., Mar 19 2008, In : FEBS Letters. 582, 6, p. 901-906 6 p.

Research output: Contribution to journalArticle

Congo Red
Derivatives
Transgenic Mice
Pick Disease of the Brain
Neurodegenerative diseases
78 Citations (Scopus)

Expression of a mutant form of the ferritin light chain gene induces neurodegeneration and iron overload in transgenic mice

Vidal, R., Miravalle, L., Gao, X., Barbeito, A. G., Baraibar, M. A., Hekmatyar, S. K., Widel, M., Bansal, N., Delisle, M. B. & Ghetti, B., Jan 2 2008, In : Journal of Neuroscience. 28, 1, p. 60-67 8 p.

Research output: Contribution to journalArticle

Apoferritins
Iron Overload
Transgenic Mice
Inclusion Bodies
Ferritins
31 Citations (Scopus)

Histopathological and molecular heterogeneity among individuals with dementia associated with Presenilin mutations

Maarouf, C. L., Daugs, I. D., Spina, S., Vidal, R., Kokjohn, T. A., Patton, R. L., Kalback, W. M., Luehrs, D. C., Walker, D. G., Castaño, E. M., Beach, T. G., Ghetti, B. & Roher, A. E., 2008, In : Molecular Neurodegeneration. 3, 1, 20.

Research output: Contribution to journalArticle

Presenilins
Dementia
Mutation
Amyloid Precursor Protein Secretases
Alzheimer Disease
24 Citations (Scopus)

In vivo and postmortem clinicoanatomical correlations in frontotemporal dementia and parkinsonism linked to chromosome 17

Ghetti, B., Spina, S., Murrell, J. R., Huey, E. D., Pietrini, P., Sweeney, B., Wassermann, E. M., Keohane, C., Farlow, M. & Grafman, J., Mar 2008, In : Neurodegenerative Diseases. 5, 3-4, p. 215-217 3 p.

Research output: Contribution to journalArticle

Frontotemporal Dementia
Chromosomes, Human, Pair 17
Parkinsonian Disorders
Microtubule-Associated Proteins
Mutation
21 Citations (Scopus)

Presenilin-1 280Glu→ala mutation alters C-terminal APP processing yielding longer Aβ peptides: Implications for Alzheimer's disease

Van Vickle, G. D., Esh, C. L., Kokjohn, T. A., Patton, R. L., Kalback, W. M., Luehrs, D. C., Beach, T. G., Newel, A. J., Lopera, F., Ghetti, B., Vidal, R., Castaño, E. M. & Roher, A. E., Mar 2008, In : Molecular Medicine. 14, 3-4, p. 184-194 11 p.

Research output: Contribution to journalArticle

Presenilins
Presenilin-1
Amyloid beta-Protein Precursor
Alzheimer Disease
Amyloid
53 Citations (Scopus)

The tauopathy associated with mutation +3 in intron 10 of Tau: Characterization of the MSTD family

Spina, S., Farlow, M., Unverzagt, F., Kareken, D., Murrell, J. R., Fraser, G., Epperson, F., Crowther, R. A., Spillantini, M. G., Goedert, M. & Ghetti, B., Jan 2008, In : Brain. 131, 1, p. 72-89 18 p.

Research output: Contribution to journalArticle

Tauopathies
Frontotemporal Dementia
Introns
Neuroimaging
Cerebral Cortex
87 Citations (Scopus)

White matter tauopathy with globular glial inclusions: A distinct sporadic frontotemporal lobar segeneration

Kovacs, G. G., Majtenyi, K., Spina, S., Murrell, J. R., Gelpi, E., Hoftberger, R., Fraser, G., Crowther, R. A., Goedert, M., Budka, H. & Ghetti, B., Oct 2008, In : Journal of Neuropathology and Experimental Neurology. 67, 10, p. 963-975 13 p.

Research output: Contribution to journalArticle

Tauopathies
Neuroglia
Frontotemporal Dementia
Frontal Lobe
Temporal Lobe
2007
142 Citations (Scopus)

Accumulation of prion protein in the brain that is not associated with transmissible disease

Piccardo, P., Manson, J. C., King, D., Ghetti, B. & Barron, R. M., Mar 13 2007, In : Proceedings of the National Academy of Sciences of the United States of America. 104, 11, p. 4712-4717 6 p.

Research output: Contribution to journalArticle

Prion Diseases
Brain
Amyloid
Amyloid Plaques
Brain Diseases
31 Citations (Scopus)

Alois Alzheimer: His life and times

Goedert, M. & Ghetti, B., Jan 2007, In : Brain Pathology. 17, 1, p. 57-62 6 p.

Research output: Contribution to journalArticle

Dementia
World War I
Anniversaries and Special Events
Names
Germany
39 Citations (Scopus)

Association of a presenilin 1 S170F mutation with a novel Alzheimer disease molecular phenotype

Piccini, A., Zanusso, G., Borghi, R., Noviello, C., Monaco, S., Russo, R., Damonte, G., Armirotti, A., Gelati, M., Giordano, R., Zambenedetti, P., Russo, C., Ghetti, B. & Tabaton, M., May 2007, In : Archives of Neurology. 64, 5, p. 738-745 8 p.

Research output: Contribution to journalArticle

Presenilin-1
Alzheimer Disease
Phenotype
Mutation
Protein Precursors
18 Citations (Scopus)

Clinical and genetic features of families with frontotemporal dementia and parkinsonism linked to chromosome 17 with a P301S tau mutation

Baba, Y., Baker, M. C., Le Ber, I., Brice, A., Maeck, L., Kohlhase, J., Yasuda, M., Stoppe, G., Bugiani, O., Sperfeld, A. D., Tsuboi, Y., Uitti, R. J., Farrer, M. J., Ghetti, B., Hutton, M. L. & Wszolek, Z. K., Jul 2007, In : Journal of Neural Transmission. 114, 7, p. 947-950 4 p.

Research output: Contribution to journalArticle

Frontotemporal Dementia
Chromosomes, Human, Pair 17
Parkinsonian Disorders
Haplotypes
Mutation
62 Citations (Scopus)

Clinicopathologic features of frontotemporal dementia with Progranulin sequence variation

Spina, S., Murrell, J. R., Huey, E. D., Wassermann, E. M., Pietrini, P., Baraibar, M. A., Barbeito, A. G., Troncoso, J. C., Vidal, R., Ghetti, B. & Grafman, J., Mar 2007, In : Neurology. 68, 11, p. 820-827 8 p.

Research output: Contribution to journalArticle

Frontotemporal Dementia
Frontotemporal Lobar Degeneration
Intranuclear Inclusion Bodies
Ubiquitin
Atrophy
70 Citations (Scopus)

Corticobasal syndrome associated with the A9D Progranulin mutation

Spina, S., Murrell, J. R., Huey, E. D., Wassermann, E. M., Pietrini, P., Grafman, J. & Ghetti, B., Oct 2007, In : Journal of Neuropathology and Experimental Neurology. 66, 10, p. 892-900 9 p.

Research output: Contribution to journalArticle

Ubiquitin
Frontotemporal Lobar Degeneration
Parietal Lobe
Parkinsonian Disorders
Mutation
9 Citations (Scopus)

Generation and survival of midbrain dopaminergic neurons in weaver mice

Martí, J., Santa-Cruz, M. C., Bayer, S. A., Ghetti, B. & Hervás, J. P., Aug 2007, In : International Journal of Developmental Neuroscience. 25, 5, p. 299-307 9 p.

Research output: Contribution to journalArticle

Neurologic Mutant Mice
Dopaminergic Neurons
Mesencephalon
Neurons
Ventral Tegmental Area
24 Citations (Scopus)

Increase in the relative expression of tau with four microtubule binding repeat regions in frontotemporal lobar degeneration and progressive supranuclear palsy brains

Ingelsson, M., Ramasamy, K., Russ, C., Freeman, S. H., Orne, J., Raju, S., Matsui, T., Growdon, J. H., Frosch, M. P., Ghetti, B., Brown, R. H., Irizarry, M. C. & Hyman, B. T., Nov 2007, In : Acta Neuropathologica. 114, 5, p. 471-479 9 p.

Research output: Contribution to journalArticle

Frontotemporal Lobar Degeneration
Progressive Supranuclear Palsy
Microtubules
Brain
Frontotemporal Dementia
3 Citations (Scopus)

Performance on MMSE sub-items and education level in presenilin-1 mutation carriers without dementia

Ringman, J. M., Rodriguez, Y., Diaz-Olavarrieta, C., Chavez, M., Thompson, M., Fairbanks, L., Paz, F., Varpetian, A., Chaparro, H., Macias-Islas, M. A., Murrell, J., Ghetti, B. & Kawas, C., Apr 2007, In : International Psychogeriatrics. 19, 2, p. 323-332 10 p.

Research output: Contribution to journalArticle

Presenilin-1
Dementia
Education
Mutation
Alzheimer Disease
164 Citations (Scopus)

Phenotypic variability associated with progranulin haploinsufficiency in patients with the common 1477C→T (Arg493X) mutation: an international initiative

Rademakers, R., Baker, M., Gass, J., Adamson, J., Huey, E. D., Momeni, P., Spina, S., Coppola, G., Karydas, A. M., Stewart, H., Johnson, N., Hsiung, G. Y., Kelley, B., Kuntz, K., Steinbart, E., Wood, E. M., Yu, C. E., Josephs, K., Sorenson, E., Womack, K. B. & 30 others, Weintraub, S., Pickering-Brown, S. M., Schofield, P. R., Brooks, W. S., Van Deerlin, V. M., Snowden, J., Clark, C. M., Kertesz, A., Boylan, K., Ghetti, B., Neary, D., Schellenberg, G. D., Beach, T. G., Mesulam, M., Mann, D., Grafman, J., Mackenzie, I. R., Feldman, H., Bird, T., Petersen, R., Knopman, D., Boeve, B., Geschwind, D. H., Miller, B., Wszolek, Z., Lippa, C., Bigio, E. H., Dickson, D., Graff-Radford, N. & Hutton, M., Oct 2007, In : The Lancet Neurology. 6, 10, p. 857-868 12 p.

Research output: Contribution to journalArticle

Frontotemporal Lobar Degeneration
Haploinsufficiency
Mutation
Haplotypes
Age of Onset
28 Citations (Scopus)

Prion protein with an octapeptide insertion has impaired neuroprotective activity in transgenic mice

Li, A., Piccardo, P., Barmada, S. J., Ghetti, B. & Harris, D. A., Jun 6 2007, In : EMBO Journal. 26, 11, p. 2777-2785 9 p.

Research output: Contribution to journalArticle

Transgenic Mice
Prions
Mutation
Prion Proteins
Prion Diseases
9 Citations (Scopus)

Purkinje cell age-distribution in fissures and in foliar crowns: A comparative study in the weaver cerebellum

Martí, J., Santa-Cruz, M. C., Bayer, S. A., Ghetti, B. & Hervás, J. P., Dec 2007, In : Brain Structure and Function. 212, 3-4, p. 347-357 11 p.

Research output: Contribution to journalArticle

Purkinje Cells
Age Distribution
Crowns
Cerebellum
Neurologic Mutant Mice

Symposium: Tau protein and neurodegeneration

Ghetti, B. & Goedert, M., Jan 2007, In : Brain Pathology. 17, 1, p. 56 1 p.

Research output: Contribution to journalArticle

tau Proteins
32 Citations (Scopus)

The genetics of very early onset Alzheimer disease

Filley, C. M., Rollins, Y. D., Alan Anderson, C., Arciniegas, D. B., Howard, K. L., Murrell, J. R., Boyer, P. J., Kleinschmidt-DeMasters, B. K. & Ghetti, B., Sep 2007, In : Cognitive and Behavioral Neurology. 20, 3, p. 149-156 8 p.

Research output: Contribution to journalArticle

Presenilin-1
Alzheimer Disease
Mutation
Dementia
Frontotemporal Dementia
247 Citations (Scopus)

The National Alzheimer's Coordinating Center (NACC) database: The uniform data set

Beekly, D. L., Ramos, E. M., Lee, W. W., Deitrich, W. D., Jacka, M. E., Wu, J., Hubbard, J. L., Koepsell, T. D., Morris, J. C., Kukull, W. A., Reiman, E. M., Kowall, N., Landreth, G., Shelanski, M., Welsh-Bohmer, K., Levey, A. I., Potter, H., Ghetti, B., Price, D., Hyman, B. & 20 others, Petersen, R. C., Sano, M., Ferris, S. H., Mesulam, M. M., Kaye, J., Bennett, D. A., Yesavage, J., Marson, D., Beck, C., DeCarli, C., Cotman, C., Cummings, J. L., Thal, L. J., Markesbery, W., Gilman, S., Trojanowski, J. Q., DeKosky, S. T., Chui, H., Rosenberg, R. & Raskind, M., Jul 2007, In : Alzheimer Disease and Associated Disorders. 21, 3, p. 249-258 10 p.

Research output: Contribution to journalArticle

Alzheimer Disease
Databases
National Institute on Aging (U.S.)
Advisory Committees
Information Storage and Retrieval
23 Citations (Scopus)

The novel Tau mutation G335S: Clinical, neuropathological and molecular characterization

Spina, S., Murrell, J. R., Yoshida, H., Ghetti, B., Bermingham, N., Sweeney, B., Dlouhy, S., Crowther, R. A., Goedert, M. & Keohane, C., Apr 2007, In : Acta Neuropathologica. 113, 4, p. 461-470 10 p.

Research output: Contribution to journalArticle

Microtubules
Mutation
Aptitude
Ideomotor Apraxia
Frontotemporal Dementia
13 Citations (Scopus)

The ε isoform of 14-3-3 protein is a component of the prion protein amyloid deposits of Gerstmann-Sträussler-Scheinker disease

Di Fede, G., Giaccone, G., Limido, L., Mangieri, M., Suardi, S., Puoti, G., Morbin, M., Mazzoleni, G., Ghetti, B. & Tagliavini, F., Feb 2007, In : Journal of Neuropathology and Experimental Neurology. 66, 2, p. 124-130 7 p.

Research output: Contribution to journalArticle

14-3-3 Proteins
Amyloid Plaques
Protein Isoforms
Creutzfeldt-Jakob Syndrome
Prion Proteins
2006
11 Citations (Scopus)

Aberrantly regulated proteins in frontotemporal dementia

Schweitzer, K., Decker, E., Zhu, L., Miller, R. E., Mirra, S. S., Spina, S., Ghetti, B., Wang, M. & Murrell, J., Sep 22 2006, In : Biochemical and Biophysical Research Communications. 348, 2, p. 465-472 8 p.

Research output: Contribution to journalArticle

Frontotemporal Dementia
Ubiquitin Thiolesterase
Chromosomes, Human, Pair 17
Oxidative stress
Pathology
406 Citations (Scopus)

Aβ42-driven cerebral amyloidosis in transgenic mice reveals early and robust pathology

Radde, R., Bolmont, T., Kaeser, S. A., Coomaraswamy, J., Lindau, D., Stoltze, L., Calhoun, M. E., Jäggi, F., Wolburg, H., Gengler, S., Haass, C., Ghetti, B., Czech, C., Hölscher, C., Mathews, P. M. & Jucker, M., Sep 2006, In : EMBO Reports. 7, 9, p. 940-946 7 p.

Research output: Contribution to journalArticle

Pathology
Amyloid
Transgenic Mice
Neurons
Breeding
28 Citations (Scopus)

Cell-cycle markers in a transgenic mouse model of human tauopathy: Increased levels of cyclin-dependent kinase inhibitors p21Cip1 and p27Kip1

Delobel, P., Lavenir, I., Ghetti, B., Holzer, M. & Goedert, M., Mar 2006, In : American Journal of Pathology. 168, 3, p. 878-887 10 p.

Research output: Contribution to journalArticle

Tauopathies
Cyclin-Dependent Kinases
tau Proteins
Transgenic Mice
Cell Cycle
66 Citations (Scopus)

Characteristics of frontotemporal dementia patients with a Progranulin mutation

Huey, E. D., Grafman, J., Wassermann, E. M., Pietrini, P., Tierney, M. C., Ghetti, B., Spina, S., Baker, M., Hutton, M., Elder, J. W., Berger, S. L., Heflin, K. A., Hardy, J. & Momeni, P., Sep 2006, In : Annals of Neurology. 60, 3, p. 374-380 7 p.

Research output: Contribution to journalArticle

Frontotemporal Dementia
Mutation
Genes
Deoxyglucose
Positron-Emission Tomography
21 Citations (Scopus)

Comparison of extent of tau pathology in patients with frontotemporal dementia with Parkinsonism linked to chromosome 17 (FTDP-17), frontotemporal lobar degeneration with Pick bodies and early onset Alzheimer's disease

Shiarli, A. M., Jennings, R., Shi, J., Bailey, K., Davidson, Y., Tian, J., Bigio, E. H., Ghetti, B., Murrell, J. R., Delisle, M. B., Mirra, S., Crain, B., Zolo, P., Arima, K., Iseki, E., Murayama, S., Kretzschmar, H., Neumann, M., Lippa, C., Halliday, G. & 8 others, MacKenzie, J., Khan, N., Ravid, R., Dickson, D., Wszolek, Z., Iwatsubo, T., Pickering-Brown, S. M. & Mann, D. M. A., Aug 2006, In : Neuropathology and Applied Neurobiology. 32, 4, p. 374-387 14 p.

Research output: Contribution to journalArticle

Frontotemporal Lobar Degeneration
Frontotemporal Dementia
Chromosomes, Human, Pair 17
Alzheimer Disease
Pathology
1 Citation (Scopus)

Frontotemporal dementia: The post-tau era

Ghetti, B. & Goebel, H. H., Aug 2006, In : Neurology. 67, 4, p. 560-561 2 p.

Research output: Contribution to journalArticle

DNA Mutational Analysis
Inclusion Body Myositis
Chromosome Disorders
Osteitis Deformans
tau Proteins
61 Citations (Scopus)

Frontotemporal dementia and parkinsonism linked to chromosome 17 (FTDP-17)

Wszolek, Z. K., Tsuboi, Y., Ghetti, B., Pickering-Brown, S., Baba, Y. & Cheshire, W. P., 2006, In : Orphanet Journal of Rare Diseases. 1, 1, 30.

Research output: Contribution to journalArticle

Frontotemporal Dementia
Chromosomes, Human, Pair 17
Parkinsonian Disorders
Mutation
Microtubules
29 Citations (Scopus)

Gerstmann-Sträussler-Scheinker: A new phenotype with 'curly' PrP deposits

Colucci, M., Moleres, F. J., Xie, Z. L., Ray-Chaudhury, A., Gutti, S., Butefisch, C. M., Cervenakova, L., Wang, W., Goldfarb, L. G., Kong, Q., Ghetti, B., Chen, S. G. & Gambetti, P., Jul 2006, In : Journal of Neuropathology and Experimental Neurology. 65, 7, p. 642-651 10 p.

Research output: Contribution to journalArticle

Phenotype
Prion Diseases
Peptide Hydrolases
Prion Proteins
Staining and Labeling
69 Citations (Scopus)

Hereditary diffuse leukoencephalopathy with spheroids: Clinical, pathologic and genetic studies of a new kindred

Baba, Y., Ghetti, B., Baker, M. C., Uitti, R. J., Hutton, M. L., Yamaguchi, K., Bird, T., Lin, W., DeLucia, M. W., Dickson, D. W. & Wszolek, Z. K., Apr 2006, In : Acta Neuropathologica. 111, 4, p. 300-311 12 p.

Research output: Contribution to journalArticle

Crystallins
Neurofilament Proteins
Amyloidogenic Proteins
Pyramidal Tracts
Protein Precursors

Mutations in the tau gene (MAPT) in FTDP-17: The family with Multiple System Tauopathy with Presenile Dementia (MSTD)

Spillantini, M. G., Murrell, J. R., Goedert, M., Farlow, M., Klug, A. & Ghetti, B., 2006, In : Journal of Alzheimer's Disease. 9, SUPPL. 3, p. 373-380 8 p.

Research output: Contribution to journalArticle

Frontotemporal Dementia
Mutation
Genes
Introns
Exons

Neurodegeneration and hereditary dementias: 40 Years of learning

Ghetti, B., 2006, In : Journal of Alzheimer's Disease. 9, SUPPL. 3, p. 45-52 8 p.

Research output: Contribution to journalArticle

Dementia
Learning
Exploratory Behavior
Anniversaries and Special Events
Nervous System Diseases
214 Citations (Scopus)

Pathological changes in dopaminergic nerve cells of the substantia nigra and olfactory bulb in mice transgenic for truncated human α-synuclein(1- 120): Implications for lewy body disorders

Tofaris, G. K., Reitböck, P. G., Humby, T., Lambourne, S. L., O'Connell, M., Ghetti, B., Gossage, H., Emson, P. C., Wilkinson, L. S., Goedert, M. & Spillantini, M. G., 2006, In : Journal of Neuroscience. 26, 15, p. 3942-3950 9 p.

Research output: Contribution to journalArticle

Synucleins
Lewy Bodies
Olfactory Bulb
Substantia Nigra
Transgenic Mice
22 Citations (Scopus)

Pathologic prion protein is specifically recognized in situ by a novel PrP conformational antibody

Moroncini, G., Mangieri, M., Morbin, M., Mazzoleni, G., Ghetti, B., Gabrielli, A., Williamson, R. A., Giaccone, G. & Tagliavini, F., Sep 2006, In : Neurobiology of Disease. 23, 3, p. 717-724 8 p.

Research output: Contribution to journalArticle

Prion Diseases
Antibodies
Immunoglobulin G
Brain
Prions
34 Citations (Scopus)

The A431E mutation in PSEN1 causing Familial Alzheimer's Disease originating in Jalisco State, Mexico: An additional fifteen families

Murrell, J., Ghetti, B., Cochran, E., Macias-Islas, M. A., Medina, L., Varpetian, A., Cummings, J. L., Mendez, M. F., Kawas, C., Chui, H. & Ringman, J. M., Nov 2006, In : Neurogenetics. 7, 4, p. 277-279 3 p.

Research output: Contribution to journalArticle

Mexico
Alzheimer Disease
Mutation
Genes
Alleles
2005
42 Citations (Scopus)

Abundant neuritic inclusions and microvacuolar changes in a case of diffuse Lewy body disease with the A53T mutation in the α-synuclein gene

Yamaguchi, K., Cochran, E. J., Murrell, J. R., Polymeropoulos, M. H., Shannon, K. M., Crowther, R. A., Goedert, M. & Ghetti, B., Sep 2005, In : Acta Neuropathologica. 110, 3, p. 298-305 8 p.

Research output: Contribution to journalArticle

Synucleins
Lewy Body Disease
Neurites
Mutation
Brain
27 Citations (Scopus)

Altered APP processing in PDAPP (Val717 → Phe) transgenic mice yields extended-length Aβ peptides

Esh, C., Patton, L., Kalback, W., Kokjohn, T. A., Lopez, J., Brune, D., Newell, A. J., Beach, T., Schenk, D., Games, D., Paul, S., Bales, K., Ghetti, B., Castaño, E. M. & Roher, A. E., Oct 25 2005, In : Biochemistry. 44, 42, p. 13807-13819 13 p.

Research output: Contribution to journalArticle

Amyloid beta-Protein Precursor
Transgenic Mice
Alzheimer Disease
Peptides
Serum Amyloid A Protein
112 Citations (Scopus)

Amino-terminally truncated Aβ peptide species are the main component of cotton wool plaques

Miravalle, L., Calero, M., Takao, M., Roher, A. E., Ghetti, B. & Vidal, R., Aug 16 2005, In : Biochemistry. 44, 32, p. 10810-10821 12 p.

Research output: Contribution to journalArticle

Wool
Cotton
Peptides
Presenilin-1
Microdissection
77 Citations (Scopus)

Bax deletion prevents neuronal loss but not neurological symptoms in a transgenic model of inherited prion disease

Chiesa, R., Piccardo, P., Dossena, S., Nowoslawski, L., Roth, K. A., Ghetti, B. & Harris, D. A., Jan 4 2005, In : Proceedings of the National Academy of Sciences of the United States of America. 102, 1, p. 238-243 6 p.

Research output: Contribution to journalArticle

Prion Diseases
Phenotype
bcl-2 Genes
Nerve Degeneration
Cerebellar Ataxia
17 Citations (Scopus)

Characterization of the F198S prion protein mutation: Enhanced glycosylation and defective refolding

Zaidi, S. I. A., Richardson, S. L., Capellari, S., Song, L., Smith, M. A., Ghetti, B., Sy, M. S., Gambetti, P. & Petersen, R. B., 2005, In : Journal of Alzheimer's Disease. 7, 2, p. 159-171 13 p.

Research output: Contribution to journalArticle

Prion Diseases
Gerstmann-Straussler-Scheinker Disease
Glycosylation
Mutant Proteins
Mutation
30 Citations (Scopus)

Chitin-like polysaccharides in Alzheimer's disease brains

Castellani, R. J., Siedlak, S. L., Fortino, A. E., Perry, G., Ghetti, B. & Smith, M. A., Oct 2005, In : Current Alzheimer Research. 2, 4, p. 419-423 5 p.

Research output: Contribution to journalArticle

Chitin
Polysaccharides
Alzheimer Disease
Glucosamine
Brain
47 Citations (Scopus)

Longitudinal characterization of two siblings with frontotemporal dementia and parkinsonism linked to chromosome 17 associated with the S305N tau mutation

Boeve, B. F., Tremont-Lukats, I. W., Waclawik, A. J., Murrell, J. R., Hermann, B., Jack, C. R., Shiung, M. M., Smith, G. E., Nair, A. R., Lindor, N., Koppikar, V. & Ghetti, B., Apr 2005, In : Brain. 128, 4, p. 752-772 21 p.

Research output: Contribution to journalArticle

Frontotemporal Dementia
Chromosomes, Human, Pair 17
Siblings
Mutation
Parkinsonian Disorders