Bernardino Ghetti &ndash; Publications

Article

Gerstmann-sträussler-scheinker disease and anchorless prion protein mice share prion conformational properties diverging from sporadic creutzfeldt-jakob disease

Zanusso, G., Fiorini, M., Ferrari, S., Meade-White, K., Barbieri, I., Brocchi, E., Ghetti, B. & Monaco, S., Feb 21 2014, In : Journal of Biological Chemistry. 289, 8, p. 4870-4881 12 p.

Research output: Contribution to journal › Article

Prion Diseases

Prions

Glycosylphosphatidylinositols

Inborn Genetic Diseases

Medical Genetics

141 Citations (Scopus)

Gerstmann-Sträussler-Scheinker disease and the Indiana kindred

Ghetti, B., Dlouhy, S., Giaccone, G., Bugiani, O., Frangione, B., Farlow, M. & Tagliavini, F., 1995, In : Brain Pathology. 5, 1, p. 61-75 15 p.

Research output: Contribution to journal › Article

Codon

Mutation

Amyloidosis

Spastic Paraparesis

Prion Diseases

2 Citations (Scopus)

Gerstmann-Sträussler-Scheinker disease revisited: accumulation of covalently-linked multimers of internal prion protein fragments

Cracco, L., Xiao, X., Nemani, S. K., Lavrich, J., Cali, I., Ghetti, B., Notari, S., Surewicz, W. K. & Gambetti, P., May 29 2019, In : Acta neuropathologica communications. 7, 1, 1 p.

Research output: Contribution to journal › Article

Open Access

Creutzfeldt-Jakob Syndrome

Prion Diseases

Molecular Weight

Epitope Mapping

Endopeptidase K

29 Citations (Scopus)

Gerstmann-Sträussler-Scheinker disease subtypes efficiently transmit in bank voles as genuine prion diseases

Pirisinu, L., Di Bari, M. A., D'Agostino, C., Marcon, S., Riccardi, G., Poleggi, A., Cohen, M. L., Appleby, B. S., Gambetti, P., Ghetti, B., Agrimi, U. & Nonno, R., Feb 4 2016, In : Scientific Reports. 6, 20443.

Research output: Contribution to journal › Article

Arvicolinae

Prion Diseases

Peptide Hydrolases

Rodent Diseases

Mutation

44 Citations (Scopus)

Gerstmann-sträussler-scheinker disease with mutation at codon 102 and methionine at codon 129 of PRNP in previously unreported patients

Young, K., Jones, C. K., Piccardo, P., Lazzarini, A., Golbe, L. I., Zimmerman, T. R., Dickson, D. W., McLachlan, D. C., St. George-Hyslop, P., Lennox, A., Perlman, S., Vinters, H. V., Hodes, M. E., Dlouhy, S. & Ghetti, B., Jun 1995, In : Neurology. 45, 6, p. 1127-1134 8 p.

Research output: Contribution to journal › Article

Codon

Methionine

Mutation

Genes

Thymine

47 Citations (Scopus)

Gerstmann-Straussler-Scheinker disease with the PRNP P102L mutation and valine at codon 129

Young, K., Clark, H. B., Piccardo, P., Dlouhy, S. & Ghetti, B., Feb 1997, In : Molecular Brain Research. 44, 1, p. 147-150 4 p.

Research output: Contribution to journal › Article

Gerstmann-Straussler-Scheinker Disease

Valine

Codon

Mutation

Methionine

47 Citations (Scopus)

GFP-tagged prion protein is correctly localized and functionally active in the brains of transgenic mice

Barmada, S., Piccardo, P., Yamaguchi, K., Ghetti, B. & Harris, D. A., Aug 2004, In : Neurobiology of Disease. 16, 3, p. 527-537 11 p.

Research output: Contribution to journal › Article

Transgenic Mice

Glycolipids

Brain

Prion Diseases

Prions

15 Citations (Scopus)

Glial cell line-derived neurotrophic factor protects midbrain dopamine neurons from the lethal action of the weaver gene: A quantitative immunocytochemical study

Broome, J. D., Wills, K. V., Lapchak, P. A., Ghetti, B., Camp, L. L. & Bayer, S. A., Aug 5 1999, In : Developmental Brain Research. 116, 1, p. 1-7 7 p.

Research output: Contribution to journal › Article

Glial Cell Line-Derived Neurotrophic Factor

Dopaminergic Neurons

Mesencephalon

Genes

Tyrosine

77 Citations (Scopus)

Globular glial tauopathies (GGT): Consensus recommendations

Ahmed, Z., Bigio, E. H., Budka, H., Dickson, D. W., Ferrer, I., Ghetti, B., Giaccone, G., Hatanpaa, K. J., Holton, J. L., Josephs, K. A., Powers, J., Spina, S., Takahashi, H., White, C. L., Revesz, T. & Kovacs, G. G., 2013, In : Acta Neuropathologica. 126, 4, p. 537-544 8 p.

Research output: Contribution to journal › Article

Tauopathies

Neuroglia

Consensus

Pyramidal Tracts

Motor Cortex

50 Citations (Scopus)

Guidelines for the diagnosis of dementia and Alzheimer's disease

Sorbi, S., Alberoni, M., Alfieri, P., Amici, S., Antana, D., Appollonio, I., Avanzi, S., Bartoli, A., Bergamasco, B., Bracco, L., Bruni, A., Bugiani, O., Caffarra, P., Caltagirone, C., Carolei, A., Rosa, A., Ciannella, L., Citterio, A., Daniele, A., D'Achille, G. & 59 others, Del Curatolo, G., Dell'Agnello, G., Durante, D., Farina, E., Ferrero, P., Forleo, P., Gainotti, G., Gabriele, P., Galante, E., Gallai, V., Gallassi, R., Gasparini, M., Ghetti, B., Giaccone, G., Girotti, F., Grimaldi, L., Grioli, S., Guarnieri, B. M., Grottoli, S., Iemolo, F., Latorraca, S., Le Pira, F., Lenzi, G. L., Lorusso, S., Mariani, C., Marcon, G., Mascia, V., Mearelli, S., Morante, M., Morbin, M., Musicco, M., Nardelli, E., Nichelli, P., Padovani, A., Paganini, M., Pantieri, R., Parisen, P., Parnetti, L., Passerella, B., Pettenati, C., Piacentini, S., Piccoli, F., Piccolini, C., Pizzolato, G., Provinciali, L., Pugliese, N., Redi, F., Ruggieri, R. M., Ruggiero, U., Saetta, M., Schoenuber, R., Silveri, M. C., Sorrentino, G., Sucapane, P., Stracciari, A., Tabaton, M., Tagliavini, F., Toso, V. & Valluzzi, F., Aug 2000, In : Neurological Sciences. 21, 4, p. 187-194 8 p.

Research output: Contribution to journal › Article

2 Citations (Scopus)

Haplotype-phenotype correlations in kindreds with the N279K mutation in the tau gene [1] (multiple letters)

Woodruff, B. K., Baba, Y., Hutton, M. L., Wszolek, Z. K., Tsuboi, Y., Kobayashi, T., Ghetti, B., Arima, K., Yasuda, M., Rascol, O. & Girotti, F., Aug 2004, In : Archives of Neurology. 61, 8, p. 1327 1 p.

Research output: Contribution to journal › Article

tau Proteins

Asparagine

Haplotypes

Lysine

Phenotype

69 Citations (Scopus)

Hereditary diffuse leukoencephalopathy with spheroids: Clinical, pathologic and genetic studies of a new kindred

Baba, Y., Ghetti, B., Baker, M. C., Uitti, R. J., Hutton, M. L., Yamaguchi, K., Bird, T., Lin, W., DeLucia, M. W., Dickson, D. W. & Wszolek, Z. K., Apr 2006, In : Acta Neuropathologica. 111, 4, p. 300-311 12 p.

Research output: Contribution to journal › Article

Crystallins

Neurofilament Proteins

Amyloidogenic Proteins

Pyramidal Tracts

Protein Precursors

32 Citations (Scopus)

Hereditary ferritinopathy

Vidal, R., Delisle, M. B., Rascol, O. & Ghetti, B., Mar 15 2003, In : Journal of the Neurological Sciences. 207, 1-2, p. 110-111 2 p.

Research output: Contribution to journal › Article

Nervous System Heredodegenerative Disorders

Ferritins

Neuroferritinopathy

49 Citations (Scopus)

Hereditary prion protein amyloidoses

Ghetti, B., Tagliavini, F., Takao, M., Bugiani, O. & Piccardo, P., Mar 1 2003, In : Clinics in Laboratory Medicine. 23, 1, p. 65-85 21 p.

Research output: Contribution to journal › Article

Amyloidosis

Neurofibrillary Tangles

Prion Diseases

Amyloid

Cerebral Amyloid Angiopathy

31 Citations (Scopus)

Histopathological and molecular heterogeneity among individuals with dementia associated with Presenilin mutations

Maarouf, C. L., Daugs, I. D., Spina, S., Vidal, R., Kokjohn, T. A., Patton, R. L., Kalback, W. M., Luehrs, D. C., Walker, D. G., Castaño, E. M., Beach, T. G., Ghetti, B. & Roher, A. E., 2008, In : Molecular Neurodegeneration. 3, 1, 20.

Research output: Contribution to journal › Article

Presenilins

Dementia

Mutation

Amyloid Precursor Protein Secretases

Alzheimer Disease

7 Citations (Scopus)

Human brain protein phosphorylation in vitro: Cyclic AMP stimulation of electrophoretically-separated substrates

Routtenberg, A., Morgan, D. G., Conway, R. G., Schmidt, M. J. & Ghetti, B., Oct 19 1981, In : Brain Research. 222, 2, p. 323-333 11 p.

Research output: Contribution to journal › Article

Cyclic AMP

Phosphorylation

Brain

Frontal Lobe

Proteins

2 Citations (Scopus)

Human fibroblast and stem cell resource from the Dominantly Inherited Alzheimer Network

Karch, C. M., Hernández, D., Wang, J. C., Marsh, J., Hewitt, A. W., Hsu, S., Norton, J., Levitch, D., Donahue, T., Sigurdson, W., Ghetti, B., Farlow, M., Chhatwal, J., Berman, S., Cruchaga, C., Morris, J. C., Bateman, R. J., Pébay, A. & Goate, A. M., Jul 25 2018, In : Alzheimer's Research and Therapy. 10, 1, 69.

Research output: Contribution to journal › Article

Presenilin-2

Presenilin-1

Amyloid beta-Protein Precursor

Stem Cells

Fibroblasts

23 Citations (Scopus)

Hypospermatogenesis is the cause of infertility in the Male weaver mutant mouse

Vogelweid, C. M., Verina, T., Norton, J., Harruff, R. & Ghetti, B., 1993, In : Journal of Neurogenetics. 9, 2, p. 89-104 16 p.

Research output: Contribution to journal › Article

Neurologic Mutant Mice

Oligospermia

Male Infertility

Seminiferous Tubules

Spermatids

13 Citations (Scopus)

Hypothalamic-pituitary-gonadal axis in the mutant weaver mouse

Schwartz, N. B., Szabo, M., Verina, T., Wei, J., Dlouhy, S., Won, L., Heller, A., Hodes, M. E. & Ghetti, B., 1998, In : Neuroendocrinology. 68, 6, p. 374-385 12 p.

Research output: Contribution to journal › Article

Neurologic Mutant Mice

Homozygote

Seminiferous Epithelium

Follicle Stimulating Hormone

Luteinizing Hormone

276 Citations (Scopus)

Identification of common variants influencing risk of the tauopathy progressive supranuclear palsy

Höglinger, G. U., Melhem, N. M., Dickson, D. W., Sleiman, P. M. A., Wang, L. S., Klei, L., Rademakers, R., De Silva, R., Litvan, I., Riley, D. E., Van Swieten, J. C., Heutink, P., Wszolek, Z. K., Uitti, R. J., Vandrovcova, J., Hurtig, H. I., Gross, R. G., Maetzler, W., Goldwurm, S., Tolosa, E. & 116 others, Borroni, B., Pastor, P., Cantwell, L. B., Han, M. R., Dillman, A., Van Der Brug, M. P., Gibbs, J. R., Cookson, M. R., Hernandez, D. G., Singleton, A. B., Farrer, M. J., Yu, C. E., Golbe, L. I., Revesz, T., Hardy, J., Lees, A. J., Devlin, B., Hakonarson, H., Müller, U., Schellenberg, G. D., Albin, R. L., Alonso, E., Antonini, A., Apfelbacher, M., Arnold, S. E., Avila, J., Beach, T. G., Beecher, S., Berg, D., Bird, T. D., Bogdanovic, N., Boon, A. J. W., Bordelon, Y., Brice, A., Budka, H., Canesi, M., Chiu, W. Z., Cilia, R., Colosimo, C., De Deyn, P. P., De Yebenes, J. G., Kaat, L. D., Duara, R., Durr, A., Engelborghs, S., Fabbrini, G., Finch, N. A., Flook, R., Frosch, M. P., Gaig, C., Galasko, D. R., Gasser, T., Gearing, M., Geller, E. T., Ghetti, B., Graff-Radford, N. R., Grossman, M., Hall, D. A., Hazrati, L. N., Höllerhage, M., Jankovic, J., Juncos, J. L., Karydas, A., Kretzschmar, H. A., Leber, I., Lee, V. M., Lieberman, A. P., Lyons, K. E., Mariani, C., Masliah, E., Massey, L. A., McLean, C. A., Meucci, N., Miller, B. L., Mollenhauer, B., Möller, J. C., Morris, H. R., Morris, C., O'Sullivan, S. S., Oertel, W. H., Ottaviani, D., Padovani, A., Pahwa, R., Pezzoli, G., Pickering-Brown, S., Poewe, W., Rabano, A., Rajput, A., Reich, S. G., Respondek, G., Roeber, S., Rohrer, J. D., Ross, O. A., Rossor, M. N., Sacilotto, G., Seeley, W. W., Seppi, K., Silveira-Moriyama, L., Spina, S., Srulijes, K., St. George-Hyslop, P., Stamelou, M., Standaert, D. G., Tesei, S., Tourtellotte, W. W., Trenkwalder, C., Troakes, C., Trojanowski, J. Q., Troncoso, J. C., Van Deerlin, V. M., Vonsattel, J. P. G., Wenning, G. K., White, C. L., Winter, P., Zarow, C. & Zecchinelli, A. L., Jul 2011, In : Nature Genetics. 43, 7, p. 699-705 7 p.

Research output: Contribution to journal › Article

Tauopathies

Progressive Supranuclear Palsy

Membrane Fusion Proteins

Unfolded Protein Response

Genome-Wide Association Study

6 Citations (Scopus)

Identification of functional variants from whole-exome sequencing, combined with neuroimaging genetics

Nho, K., Corneveaux, J. J., Kim, S., Lin, H., Risacher, S. L., Shen, L., Swaminathan, S., Ramanan, V. K., Liu, Y., Foroud, T., Inlow, M. H., Siniard, A. L., Reiman, R. A., Aisen, P. S., Petersen, R. C., Green, R. C., Jack, C. R., Weiner, M. W., Baldwin, C. T., Lunetta, K. & 14 others, Farrer, L. A., Furney, S. J., Lovestone, S., Simmons, A., Mecocci, P., Vellas, B., Tsolaki, M., Kloszewska, I., Soininen, H., McDonald, B., Farlow, M., Ghetti, B., Huentelman, M. J. & Saykin, A., Jul 2013, In : Molecular Psychiatry. 18, 7, p. 739 1 p.

Research output: Contribution to journal › Article

Exome

Genome-Wide Association Study

Neuroimaging

Atrophy

Hippocampus

86 Citations (Scopus)

Identification of TMEM230 mutations in familial Parkinson's disease

Deng, H. X., Shi, Y., Yang, Y., Ahmeti, K. B., Miller, N., Huang, C., Cheng, L., Zhai, H., Deng, S., Nuytemans, K., Corbett, N. J., Kim, M. J., Deng, H., Tang, B., Yang, Z., Xu, Y., Chan, P., Huang, B., Gao, X. P., Song, Z. & 14 others, Liu, Z., Fecto, F., Siddique, N., Foroud, T., Jankovic, J., Ghetti, B., Nicholson, D. A., Krainc, D., Melen, O., Vance, J. M., Pericak-Vance, M. A., Ma, Y. C., Rajput, A. H. & Siddique, T., Jul 1 2016, In : Nature Genetics. 48, 7, p. 733-739 7 p.

Research output: Contribution to journal › Article

Parkinson Disease

Mutation

Synaptic Vesicles

Chromosomes, Human, Pair 20

Neurons

30 Citations (Scopus)

Impact of training method on the robustness of the visual assessment of ¹⁸F-florbetaben PET scans: Results from a phase-3 study

Seibyl, J., Catafau, A. M., Barthel, H., Ishii, K., Rowe, C. C., Leverenz, J. B., Ghetti, B., Ironside, J. W., Takao, M., Akatsu, H., Murayama, S., Bullich, S., Mueller, A., Koglin, N., Schulz-Schaeffer, W. J., Hoffmann, A., Sabbagh, M. N., Stephens, A. W. & Sabri, O., Jun 1 2016, In : Journal of Nuclear Medicine. 57, 6, p. 900-906 7 p.

Research output: Contribution to journal › Article

Silver Staining

Positron-Emission Tomography

Immunohistochemistry

Amyloid Plaques

Amyloid

137 Citations (Scopus)

Incidence and spectrum of sporadic Creutzfeldt-Jakob disease variants with mixed phenotype and co-occurrence of PrPSc types: An updated classification

Parchi, P., Strammiello, R., Notari, S., Giese, A., Langeveld, J. P. M., Ladogana, A., Zerr, I., Roncaroli, F., Cras, P., Ghetti, B., Pocchiari, M., Kretzschmar, H. & Capellari, S., Nov 2009, In : Acta Neuropathologica. 118, 5, p. 659-671 13 p.

Research output: Contribution to journal › Article

Kuru

Phenotype

Molecular Typing

Incidence

Valine

14 Citations (Scopus)

Increased Tau Phosphorylation and Tau Truncation, and Decreased Synaptophysin Levels in Mutant BRI2/Tau Transgenic Mice

Garringer, H., Murrell, J., Sammeta, N., Gnezda, A., Ghetti, B. & Vidal, R., Feb 13 2013, In : PLoS One. 8, 2, e56426.

Research output: Contribution to journal › Article

Synaptophysin

Phosphorylation

dementia

Transgenic Mice

phosphorylation

24 Citations (Scopus)

Increase in the relative expression of tau with four microtubule binding repeat regions in frontotemporal lobar degeneration and progressive supranuclear palsy brains

Ingelsson, M., Ramasamy, K., Russ, C., Freeman, S. H., Orne, J., Raju, S., Matsui, T., Growdon, J. H., Frosch, M. P., Ghetti, B., Brown, R. H., Irizarry, M. C. & Hyman, B. T., Nov 2007, In : Acta Neuropathologica. 114, 5, p. 471-479 9 p.

Research output: Contribution to journal › Article

Frontotemporal Lobar Degeneration

Progressive Supranuclear Palsy

Microtubules

Brain

Frontotemporal Dementia

9 Citations (Scopus)

Increase of a nerve growth factor-like protein in the cerebellum of pcd mutant mice

Schwartz, J. P., Ghetti, B., Truex, L. & Schmidt, M. J., 1982, In : Journal of Neuroscience Research. 8, 2-3, p. 205-211 7 p.

Research output: Contribution to journal › Article

Nerve Growth Factor

Cerebellum

Neuroglia

Proteins

Sensory Ganglia

24 Citations (Scopus)

Induction of neurofibrillary degeneration following treatment with maytansine in vivo

Ghetti, B., Mar 9 1979, In : Brain Research. 163, 1, p. 9-19 11 p.

Research output: Contribution to journal › Article

Maytansine

Tubulin

Microtubules

Spinal Injections

Intermediate Filaments

10 Citations (Scopus)

Induction of neurofibrillary tangles in cultured mouse neurons by maytanprine

Sato, Y., Kim, S. U. & Ghetti, B., 1985, In : Journal of the Neurological Sciences. 68, 2-3, p. 191-203 13 p.

Research output: Contribution to journal › Article

Neurofibrillary Tangles

Intermediate Filaments

Neurons

Microtubules

Spinal Ganglia

1 Citation (Scopus)

Influence of genetic strain background on the magnitude of behavioral recovery observed in weaver mutant mice following bilateral intrastriatal grafting of mesencephalic cell suspensions

Triarhou, L. C., Norton, J., Ghetti, B. & Hingtgen, J. N., 1992, In : Journal of Neural Transplantation and Plasticity. 3, 4, p. 253-254 2 p.

Research output: Contribution to journal › Article

Neurologic Mutant Mice

Suspensions

Genetic Background

42 Citations (Scopus)

Influence of Genetic Variation on Plasma Protein Levels in Older Adults Using a Multi-Analyte Panel

Kim, S., Swaminathan, S., Inlow, M., Risacher, S. L., Nho, K., Shen, L., Foroud, T., Petersen, R. C., Aisen, P. S., Soares, H., Toledo, J. B., Shaw, L. M., Trojanowski, J. Q., Weiner, M. W., McDonald, B., Farlow, M., Ghetti, B. & Saykin, A., Jul 23 2013, In : PLoS One. 8, 7, e70269.

Research output: Contribution to journal › Article

blood proteins

Blood Proteins

Polymorphism

Single Nucleotide Polymorphism

genetic variation

2 Citations (Scopus)

Inge Grundke-Iqbal, Ph.D. (1937-2012): the discoverer of the abnormal hyperphosphorylation of tau in Alzheimer's disease.

Alonso, A. D. C., ElAkkad, E., Gong, C., Liu, F., Tanaka, T., Kudo, T., Tatebayashi, Y., Pei, J., Wang, J., Khatoon, S., Flory, M., Ghetti, B., Gozes, I., Novak, M., Novak, M., Robakis, N. K., de Leon, M. & Iqbal, M., 2013, In : Journal of Molecular Neuroscience. 49, 2, p. 430-435 6 p.

Research output: Contribution to journal › Article

21st Century History

20th Century History

tau Proteins

Neurosciences

Glycosylation

22 Citations (Scopus)

Inhibition of insulin-like growth factor I activity contributes to the premature apoptosis of cerebellar granule neuron in weaver mutant mice: In vitro analysis

Zhong, J., Deng, J., Ghetti, B. & Lee, W. H., Oct 1 2002, In : Journal of Neuroscience Research. 70, 1, p. 36-45 10 p.

Research output: Contribution to journal › Article

Neurologic Mutant Mice

Insulin-Like Growth Factor I

Apoptosis

Neurons

IGF Type 1 Receptor

25 Citations (Scopus)

In situ hybridization analysis of Girk2 expression in the developing central nervous system in normal and weaver mice

Wei, J., Dlouhy, S., Bayer, S., Piva, R., Verina, T., Wang, Y., Feng, Y., Dupree, B., Hodes, M. E. & Ghetti, B., Jul 1997, In : Journal of Neuropathology and Experimental Neurology. 56, 7, p. 762-771 10 p.

Research output: Contribution to journal › Article

Neurologic Mutant Mice

Mesencephalon

Cerebellum

In Situ Hybridization

Central Nervous System

46 Citations (Scopus)

Insomnia associated with thalamic involvement in E200K Creutzfeldt-Jakob disease

Taratuto, A. L., Piccardo, P., Reich, E. G., Chen, S. G., Sevlever, G., Schultz, M., Luzzi, A. A., Rugiero, M., Abecasis, G., Endelman, M., Garcia, A. M., Capellari, S., Xie, Z., Lugaresi, E., Gambetti, P., Dlouhy, S. & Ghetti, B., Feb 12 2002, In : Neurology. 58, 3, p. 362-367 6 p.

Research output: Contribution to journal › Article

Creutzfeldt-Jakob Syndrome

Sleep Initiation and Maintenance Disorders

Haplotypes

Endopeptidase K

Gliosis

123 Citations (Scopus)

Intracellular Ferritin Accumulation in Neural and Extraneural Tissue Characterizes A Neurodegenerative Disease Associated with A Mutation in the Ferritin Light Polypeptide Gene

Vidal, R., Ghetti, B., Takao, M., Brefel-Courbon, C., Uro-Coste, E., Glazier, B. S., Siani, V., Benson, M., Calvas, P., Miravalle, L., Rascol, O. & Delisle, M. B., Apr 2004, In : Journal of Neuropathology and Experimental Neurology. 63, 4, p. 363-380 18 p.

Research output: Contribution to journal › Article

Ferritins

Neurodegenerative Diseases

Light

Peptides

Mutation

21 Citations (Scopus)

Intraparenchymal grafting of cerebellar cell suspensions to the deep cerebellar nuclei of pcd mutant mice, with particular emphasis on re-establishment of a Purkinje cell cortico-nuclear projection

Triarhou, L. C., Low, W. C. & Ghetti, B., Apr 1992, In : Anatomy and Embryology. 185, 5, p. 409-420 12 p.

Research output: Contribution to journal › Article

Cerebellar Nuclei

Purkinje Cells

Suspensions

Cerebellar Cortex

Transplants

18 Citations (Scopus)

Intrastriatal implants of mesencephalic cell suspensions in weaver mutant mice: ultrastructural relationships of dopaminergic dendrites and axons issued from the graft

Triarhou, L. C., Brundin, P., Doucet, G., Norton, J., Björklund, A. & Ghetti, B., Jan 1990, In : Experimental Brain Research. 79, 1, p. 3-17 15 p.

Research output: Contribution to journal › Article

Neurologic Mutant Mice

Dendrites

Axons

Suspensions

Transplants

1 Citation (Scopus)

Introduction: From the desk of the guest editor

Ghetti, B., Nov 2011, In : Journal of Molecular Neuroscience. 45, 3, p. 321-322 2 p.

Research output: Contribution to journal › Article

148 Citations (Scopus)

Invited review: Frontotemporal dementia caused by microtubule-associated protein tau gene (MAPT) mutations: A chameleon for neuropathology and neuroimaging

Ghetti, B., Oblak, A. L., Boeve, B. F., Johnson, K. A., Dickerson, B. C. & Goedert, M., Feb 1 2015, In : Neuropathology and Applied Neurobiology. 41, 1, p. 24-46 23 p.

Research output: Contribution to journal › Article

Frontotemporal Dementia

Microtubule-Associated Proteins

Lizards

Neuroimaging

Positron-Emission Tomography

7 Citations (Scopus)

In vitro evidence that the reduction in mesencepalic dopaminergic neurons in the weaver heterozygote is not due to a failure in target cell interaction

Won, L., Ghetti, B., Heller, B. & Heller, A., 1997, In : Experimental Brain Research. 115, 1, p. 174-179 6 p.

Research output: Contribution to journal › Article

Dopaminergic Neurons

Heterozygote

Cell Communication

Corpus Striatum

Mesencephalon

12 Citations (Scopus)

In vitro release of endogenous dopamine from the striatum of the weaver mutant mouse

Simon, J. R., Yu, H., Richter, J. A., Vasko, M. & Ghetti, B., Nov 1991, In : Journal of Neurochemistry. 57, 5, p. 1478-1482 5 p.

Research output: Contribution to journal › Article

Neurologic Mutant Mice

Dopamine

Corpus Striatum

Amphetamine

Potassium

24 Citations (Scopus)

In vivo and postmortem clinicoanatomical correlations in frontotemporal dementia and parkinsonism linked to chromosome 17

Ghetti, B., Spina, S., Murrell, J. R., Huey, E. D., Pietrini, P., Sweeney, B., Wassermann, E. M., Keohane, C., Farlow, M. & Grafman, J., Mar 2008, In : Neurodegenerative Diseases. 5, 3-4, p. 215-217 3 p.

Research output: Contribution to journal › Article

Frontotemporal Dementia

Chromosomes, Human, Pair 17

Parkinsonian Disorders

Microtubule-Associated Proteins

Mutation

10 Citations (Scopus)

Is there a significant somatodendritic uptake of dopamine in the substantia nigra? Evidence from the weaver mutant mouse

Simon, J. R. & Ghetti, B., 1993, In : Neurochemistry International. 22, 5, p. 471-477 7 p.

Research output: Contribution to journal › Article

Neurologic Mutant Mice

Substantia Nigra

Dopamine

Desipramine

Fluoxetine

635 Citations (Scopus)

Lack of apolipoprotein E dramatically reduces amyloid beta-peptide deposition.

Bales, K. R., Verina, T., Dodel, R. C., Du, Y., Altstiel, L., Bender, M., Hyslop, P., Johnstone, E. M., Little, S. P., Cummins, D. J., Piccardo, P., Ghetti, B. & Paul, S. M., Nov 1997, In : Nature Genetics. 17, 3, p. 263-264 2 p.

Research output: Contribution to journal › Article

1 Citation (Scopus)

La teleangectasia universale, congenita, eritematosa di Bloom associata ad are-flessia osteo-tendinea ed oligofrenia: studio del primo caso italiano.

Translated title of the contribution: Congenital generalized erythematous telangiectasis of Bloom associated with osteo-tendineous areflexia and oligophrenia: the 1st case in ItalyBertolino, A., Fiore, C., Morcaldi, L., Pinto, L., Ghetti, B. & Guazzi, G. C., Nov 15 1969, In : Rassegna Internazionale di Clinica e Terapia. 49, 21, p. 1331-1347 17 p.

Research output: Contribution to journal › Article

Facial Dermatoses

Multiple Abnormalities

Photosensitivity Disorders

Dwarfism

Stretch Reflex

2 Citations (Scopus)

LATE to the PART-y

Josephs, K. A., Mackenzie, I., Frosch, M. P., Bigio, E. H., Neumann, M., Arai, T., Dugger, B. N., Ghetti, B., Grossman, M., Hasegawa, M., Herrup, K., Holton, J., Jellinger, K., Lashley, T., McAleese, K. E., Parisi, J. E., Revesz, T., Saito, Y., Vonsattel, J. P., Whitwell, J. L. & 2 others, Wisniewski, T. & Hu, W., Sep 1 2019, In : Brain : a journal of neurology. 142, 9, p. e47

Research output: Contribution to journal › Article

Open Access

6 Citations (Scopus)

Layer-specific innervation of the dopamine-deficient frontal cortex in weaver mutant mice by grafted mesencephalic dopaminergic neurones

Triarhou, L. C., Low, W. C. & Ghetti, B., Oct 1988, In : Cell and Tissue Research. 254, 1, p. 11-15 5 p.

Research output: Contribution to journal › Article

Neurologic Mutant Mice

Dopaminergic Neurons

Frontal Lobe

Neurons

Dopamine

385 Citations (Scopus)

Lewy bodies contain altered α-synuclein in brains of many familial Alzheimer's disease patients with mutations in presenilin and amyloid precursor protein genes

Lippa, C. F., Fujiwara, H., Mann, D. M. A., Giasson, B., Baba, M., Schmidt, M. L., Nee, L. E., O'Connell, B., Pollen, D. A., St. George-Hyslop, P., Ghetti, B., Nochlin, D., Bird, T. D., Cairns, N. J., Lee, V. M. Y., Iwatsubo, T. & Trojanowski, J. Q., Nov 1998, In : American Journal of Pathology. 153, 5, p. 1365-1370 6 p.

Research output: Contribution to journal › Article

Synucleins

Presenilins

Lewy Bodies

Amyloid beta-Protein Precursor

Alzheimer Disease

3 Citations (Scopus)

Linkage mapping of microdissected clones from distal mouse chromosome 16

Wei, J., Dlouhy, S., Wang, Y., Zhu, J., Fitzpatrick, L., Ghetti, B. & Hodes, M. E., May 1996, In : Somatic Cell and Molecular Genetics. 22, 3, p. 227-232 6 p.

Research output: Contribution to journal › Article

Chromosomes, Human, Pair 16

Chromosome Mapping

Clone Cells

Microdissection

Organism Cloning