Bernardino Ghetti

  • 32339 Citations
  • 88 h-Index
1967 …2020

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Publications

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1995

Neurofibrillary tangles in Niemann-Pick disease type C

Suzuki, K., Parker, C. C., Pentchev, P. G., Katz, D., Ghetti, B., D'Agostino, A. N. & Carstea, E. D., Mar 1995, In : Acta Neuropathologica. 89, 3, p. 227-238 12 p.

Research output: Contribution to journalArticle

151 Scopus citations

Selective vulnerability of late-generated dopaminergic neurons of the substantia nigra in weaver mutant mice

Bayer, S. A., Wills, K. V., Triarhou, L. C., Verina, T., Thomas, J. D. & Ghetti, B., Sep 26 1995, In : Proceedings of the National Academy of Sciences of the United States of America. 92, 20, p. 9137-9140 4 p.

Research output: Contribution to journalArticle

38 Scopus citations

Systematic differences in time of dopaminergic neuron origin between normal mice and homozygous weaver mutants

Bayer, S. A., Wills, K. V., Triarhou, L. C., Thomas, J. D. & Ghetti, B., Aug 1 1995, In : Experimental Brain Research. 105, 2, p. 200-208 9 p.

Research output: Contribution to journalArticle

22 Scopus citations

The Tyrosine Kinase Inhibitor Genistein Increases Endogenous Dopamine Release from Normal and Weaver Mutant Mouse Striatal Slices

Bare, D. J., Ghetti, B. & Richter, J. A., Nov 1995, In : Journal of Neurochemistry. 65, 5, p. 2096-2104 9 p.

Research output: Contribution to journalArticle

6 Scopus citations

Time of neuron origin and gradients of neurogenesis in midbrain dopaminergic neurons in the mouse

Bayer, S. A., Wills, K. V., Triarhou, L. C. & Ghetti, B., Aug 1 1995, In : Experimental Brain Research. 105, 2, p. 191-199 9 p.

Research output: Contribution to journalArticle

131 Scopus citations

Ventral mesencephalic grafts in the neostriatum of the weaver mutant mouse: Structural molecule and receptor studies

Triarhou, L. C., Solà, C., Mengod, G., Garcia-Ladona, F. J., Landwehrmeyer, B., Ghetti, B. & Palacios, J. M., Jan 1 1995, In : Cell Transplantation. 4, 1, p. 39-48 10 p.

Research output: Contribution to journalArticle

4 Scopus citations
1994

Age-dependent alterations in dopamine content, tyrosine hydroxylase activity, and dopamine uptake in the striatum of the weaver mutant mouse

Simon, J. R., Richter, J. A. & Ghetti, B., Feb 1 1994, In : Journal of Neurochemistry. 62, 2, p. 543-548 6 p.

Research output: Contribution to journalArticle

19 Scopus citations

Alterations in dopamine and serotonin uptake systems in the striatum of the weaver mutant mouse

Stotz, E. H., Palacios, J. M., Landwehrmeyer, B., Norton, J., Ghetti, B., Simon, J. R. & Triarhou, L. C., Feb 1 1994, In : Journal of Neural Transmission. 97, 1, p. 51-64 14 p.

Research output: Contribution to journalArticle

16 Scopus citations

Amyloid fibrils in Gerstmann-Sträussler-Scheinker disease (Indiana and Swedish Kindreds) express only PrP peptides encoded by the mutant allele

Tagliavini, F., Prelli, F., Porro, M., Rossi, G., Giaccone, G., Farlow, M. R., Dlouhy, S. R., Ghetti, B., Bugiani, O. & Frangione, B., Nov 18 1994, In : Cell. 79, 4, p. 695-703 9 p.

Research output: Contribution to journalArticle

130 Scopus citations
8 Scopus citations

cDNA approaches to isolation of the mouse mutant weaver gene

Hodes, M. E., Dlouhy, S. R., Wei, J. J., Wang, Y., Sangameswaran, L., Lazar, V., Triarhou, L. C. & Ghetti, B., Nov 1 1994, In : Neurochemical Research. 19, 11, p. 1359-1362 4 p.

Research output: Contribution to journalArticle

1 Scopus citations

Cerebrospinal fluid levels of amyloid β-protein precursor are low in gerstmann-sträussler-scheinker disease, Indiana kindred

Farlow, M. R., Ghetti, B., Dlouhy, S., Giaccone, G., Bugiani, O., Tagliavini, F. & Wagner, S., Aug 1994, In : Neurology. 44, 8, p. 1508-1510 3 p.

Research output: Contribution to journalArticle

3 Scopus citations
26 Scopus citations

Correlated quantitative studies of the neostriatum, nucleus accumbens, substantia nigra, and ventral tegmental area in normal and weaver mutant mice

Bayer, S. A., Triarhou, L. C., Thomas, J. D. & Ghetti, B., Jan 1 1994, In : Journal of Neuroscience. 14, 11 II, p. 6901-6910 10 p.

Research output: Contribution to journalArticle

Open Access
18 Scopus citations

Familial Gerstmann-Sträussler-Scheinker disease with neurofibrillary tangles

Ghetti, B., Tagliavini, F., Giaccone, G., Bugiani, O., Frangione, B., Farlow, M. R. & Dlouhy, S. R., Feb 1 1994, In : Molecular Neurobiology. 8, 1, p. 41-48 8 p.

Research output: Contribution to journalArticle

63 Scopus citations

Fatal familial insomnia and familial Creutzfeldt-Jakob disease: Different prion proteins determined by a DNA polymorphism

Monari, L., Chen, S. G., Brown, P., Parchi, P., Petersen, R. B., Mikol, J., Gray, F., Cortelli, P., Montagna, P., Ghetti, B., Goldfarb, L. G., Gajdusek, D. C., Lugaresi, E., Gambetti, P. & Autilio-Gambetti, L., Mar 29 1994, In : Proceedings of the National Academy of Sciences of the United States of America. 91, 7, p. 2839-2842 4 p.

Research output: Contribution to journalArticle

Open Access
250 Scopus citations

Molecular characterization of a novel cDNA from murine cerebellum, developmental expression, and distribution in brain

Kambouris, M., Sangameswaran, L., Triarhou, L. C., Kozak, C. A., Dlouhy, S. R., Ghetti, B. & Hodes, M. E., Sep 1994, In : Molecular Brain Research. 25, 3-4, p. 192-199 8 p.

Research output: Contribution to journalArticle

2 Scopus citations

Novel cDNA clones obtained by antibody screening of a mouse cerebellar cDNA expression library

Kambouris, M., Triarhou, L. C., Dlouhy, S. R., Sangameswaran, L., Luo, F., Ghetti, B. & Hodes, M. E., Sep 1994, In : Molecular Brain Research. 25, 3-4, p. 183-191 9 p.

Research output: Contribution to journalArticle

6 Scopus citations

Studies on the striatal dopamine uptake system of weaver mutant mice and effects of ventral mesencephalic grafts

Triarhou, L. C., Stotz, E. H., Low, W. C., Norton, J., Ghetti, B., Landwehrmeyer, B., Palacios, J. M. & Simon, J. R., Nov 1 1994, In : Neurochemical Research. 19, 11, p. 1349-1358 10 p.

Research output: Contribution to journalArticle

3 Scopus citations

The weaver mutant mouse as a model of nigrostriatal dysfunction

Simon, J. R. & Ghetti, B., Aug 1 1994, In : Molecular Neurobiology. 9, 1-3, p. 183-189 7 p.

Research output: Contribution to journalArticle

21 Scopus citations
1993

A68 is a component of paired helical filaments of Gerstmann-Sträussler-Scheinker disease, Indiana kindred

Tagliavini, F., Giaccone, G., Prelli, F., Verga, L., Porro, M., Trojanowski, J. Q., Farlow, M. R., Frangione, B., Ghetti, B. & Bugiani, O., Jul 9 1993, In : Brain research. 616, 1-2, p. 325-329 5 p.

Research output: Contribution to journalArticle

40 Scopus citations
4 Scopus citations

Characterization of amyloid familial β-peptide in familial alzheimer′s disease with APP717 mutations

Liepnieks, J. J., Ghetti, B., Farlow, M., Roses, A. D. & Benson, M. D., Dec 15 1993, In : Biochemical and Biophysical Research Communications. 197, 2, p. 386-392 7 p.

Research output: Contribution to journalArticle

11 Scopus citations

Dopamine-depleting effects of MPTP and reserpine in weaver mutant mice

Richter, J. A., Ghetti, B. & Simon, J. R., Dec 1 1993, In : Molecular and Chemical Neuropathology. 20, 3, p. 219-228 10 p.

Research output: Contribution to journalArticle

2 Scopus citations

Embryonic cerebellar graft development during acute phase of gliosis in the cerebellum of pcd mutant mice.

Chang, A. C. & Ghetti, B., 1993, In : The Chinese journal of physiology. 36, 3, p. 141-149 9 p.

Research output: Contribution to journalArticle

4 Scopus citations

Hypospermatogenesis is the cause of infertility in the Male weaver mutant mouse

Vogelweid, C. M., Verina, T., Norton, J., Harruff, R. & Ghetti, B., Jan 1 1993, In : Journal of Neurogenetics. 9, 2, p. 89-104 16 p.

Research output: Contribution to journalArticle

23 Scopus citations

Is there a significant somatodendritic uptake of dopamine in the substantia nigra? Evidence from the weaver mutant mouse

Simon, J. R. & Ghetti, B., May 1993, In : Neurochemistry International. 22, 5, p. 471-477 7 p.

Research output: Contribution to journalArticle

11 Scopus citations
7 Scopus citations
8 Scopus citations

RFLP analysis for APP 717 mutations associated with Alzheimer's disease

Zeldenrust, S. R., Murrell, J., Farlow, M., Ghetti, B., Roses, A. D. & Benson, M. D., 1993, In : Journal of Medical Genetics. 30, 6, p. 476-478 3 p.

Research output: Contribution to journalArticle

Open Access
7 Scopus citations

Serotonin content is elevated in the dopamine deficient striatum of the weaver mutant mouse

Stotz, E. H., Triarhou, L. C., Ghetti, B. & Simon, J. R., Mar 26 1993, In : Brain research. 606, 2, p. 267-272 6 p.

Research output: Contribution to journalArticle

17 Scopus citations

Synthetic peptides homologous to prion protein residues 106-147 form amyloid-like fibrils in vitro

Tagliavini, F., Prelli, F., Verga, L., Giaccone, G., Sarma, R., Gorevic, P., Ghetti, B., Passerini, F., Ghibaudi, E., Forloni, G., Salmona, M., Bugiani, O. & Frangione, B., Oct 15 1993, In : Proceedings of the National Academy of Sciences of the United States of America. 90, 20, p. 9678-9682 5 p.

Research output: Contribution to journalArticle

Open Access
226 Scopus citations

βPP participates in PrP-amyloid plaques of gerstmann-sträussler-scheinker disease, Indiana kindred

Bugiani, O., Giaccone, G., Verga, L., Pollo, B., Frangione, B., Farlow, M. R., Tagliavini, F. & Ghetti, B., Jan 1993, In : Journal of Neuropathology and Experimental Neurology. 52, 1, p. 64-70 7 p.

Research output: Contribution to journalArticle

51 Scopus citations
1992

Abnormal Eye Movements in Gerstmann-Sträussler-Scheinker Disease

Yee, R. D., Farlow, M. R., Suzuki, D. A., Betelak, K. F. & Ghetti, B., Jan 1992, In : Archives of Ophthalmology. 110, 1, p. 68-74 7 p.

Research output: Contribution to journalArticle

15 Scopus citations

Comparison of alterations in tyrosine hydroxylase, dopamine levels, and dopamine uptake in the striatum of the weaver mutant mouse

Richter, J. A., Stotz, E. H., Ghetti, B. & Simon, J. R., May 1 1992, In : Neurochemical Research. 17, 5, p. 437-441 5 p.

Research output: Contribution to journalArticle

26 Scopus citations

Degeneration of mesencephalic dopamine neurons in weaver mutant mice

Ghetti, B. & Triarhou, L. C., Mar 1992, In : Neurochemistry International. 20, SUPPL., p. 305-307 3 p.

Research output: Contribution to journalArticle

23 Scopus citations
1 Scopus citations
23 Scopus citations

Linkage of the Indiana kindred of gerstmann-sträussler-scheinker disease to the prion protein gene

Dlouhy, S. R., Hsiao, K., Farlow, M. R., Foroud, T., Conneally, P. M., Johnson, P., Prusiner, S. B., Hodes, M. E. & Ghetti, B., Apr 1992, In : Nature genetics. 1, 1, p. 64-67 4 p.

Research output: Contribution to journalArticle

176 Scopus citations

Low cerebrospinal-fluid concentrations of soluble amyloid β-protein precursor in hereditary Alzheimer's disease

Farlow, M., Ghetti, B., Benson, M. D., van Nostrand, W. E., Farrow, J. S. & Wagner, S. L., Aug 22 1992, In : The Lancet. 340, 8817, p. 453-454 2 p.

Research output: Contribution to journalArticle

54 Scopus citations

Mutant prion proteins in gerstmann-sträussler-scheinker disease with neurofibrillary tangles

Hsiao, K., Dlouhy, S. R., Farlow, M. R., Cass, C., Da Costa, M., Conneally, P. M., Hodes, M. E., Ghetti, B. & Prusiner, S. B., Apr 1992, In : Nature genetics. 1, 1, p. 68-71 4 p.

Research output: Contribution to journalArticle

204 Scopus citations

Prion protein preamyloid and amyloid deposits in Gerstmann-Sträussler-Scheinker disease, Indiana kindred

Giaccone, G., Verga, L., Bugiani, O., Frangione, B., Serban, D., Prusiner, S. B., Farlow, M. R., Ghetti, B. & Tagliavini, F., Oct 1 1992, In : Proceedings of the National Academy of Sciences of the United States of America. 89, 19, p. 9349-9353 5 p.

Research output: Contribution to journalArticle

Open Access
79 Scopus citations

Serotonin fiber innervation of cerebellar cell suspensions intraparenchymally grafted to the cerebellum of pcd mutant mice

Triarhou, L. C., Low, W. C. & Ghetti, B., May 1 1992, In : Neurochemical Research. 17, 5, p. 475-482 8 p.

Research output: Contribution to journalArticle

9 Scopus citations
23 Scopus citations
13 Scopus citations
1991

A mutation in the amyloid precursor protein associated with hereditary Alzheimer's disease

Murrell, J., Farlow, M., Ghetti, B. & Benson, M. D., Jan 1 1991, In : Science. 254, 5028, p. 97-99 3 p.

Research output: Contribution to journalArticle

883 Scopus citations

Amyloid protein of Gerstmann-Straussler-Scheinker disease (Indiana kindred) is an 11 kd fragment of prion protein with an N-terminal glycine at codon 58

Tagliavini, F., Prelli, F., Ghiso, J., Bugiani, O., Serban, D., Prusiner, S. B., Farlow, M. R., Ghetti, B. & Frangione, B., Mar 18 1991, In : EMBO Journal. 10, 3, p. 513-519 7 p.

Research output: Contribution to journalArticle

164 Scopus citations

Asymmetrical cerebral atrophy in Alzheimer's disease

Bugiani, O., Constantinidis, J., Ghetti, B., Bouras, C. & Tagliavini, F., Jan 1 1991, In : Clinical Neuropathology. 10, 2, p. 55-60 6 p.

Research output: Contribution to journalArticle

18 Scopus citations

In Vitro Release of Endogenous Dopamine from the Striatum of the Weaver Mutant Mouse

Simon, J. R., Yu, H., Richter, J. A., Vasko, M. R. & Ghetti, B., Nov 1991, In : Journal of Neurochemistry. 57, 5, p. 1478-1482 5 p.

Research output: Contribution to journalArticle

12 Scopus citations

Serotonin-immunoreactivity in the cerebellum of two neurological mutant mice and the corresponding wild-type genetic stocks

Triarhou, L. C. & Ghetti, B., Jan 1 1991, In : Journal of chemical neuroanatomy. 4, 6, p. 421-428 8 p.

Research output: Contribution to journalArticle

18 Scopus citations